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IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-10-16 DOI: 10.1016/j.soard.2024.10.002
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SOARD Category 1 CME Credit Featured Articles, Volume 20, November 2024 SOARD 第 1 类 CME 学分精选文章,第 20 卷,2024 年 11 月
IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-10-16 DOI: 10.1016/j.soard.2024.10.001
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SOARD Category 1 CME Credit Featured Articles, Volume 20, October 2024 SOARD 第 1 类 CME 学分精选文章,第 20 卷,2024 年 10 月
IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-09-09 DOI: 10.1016/j.soard.2024.08.027
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IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-09-09 DOI: 10.1016/j.soard.2024.08.028
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引用次数: 0
Who gains the most quality-of-life benefits from metabolic and bariatric surgery: findings from the prospective REBORN cohort study 谁能从代谢和减肥手术中获得最多生活质量方面的益处:前瞻性 REBORN 队列研究的结果
IF 3.1 3区 医学 Q1 SURGERY Pub Date : 2024-08-30 DOI: 10.1016/j.soard.2024.08.029
Reyhaneh Yousefi M.Sc., Tair Ben-Porat Ph.D., Ariany Marques Vieira M.Sc., Kim L. Lavoie Ph.D., Simon L. Bacon Ph.D., REBORN Study Team, S.L. Bacon, K.L. Lavoie, A. Gautier, P. Marion, A. Alberga, R. Denis, P. Garneau, G. Lavigne, R. Pescarus, S. Raymond-Carrier, S. Santosa, A.S. Studer, T. Ben-Porat, K. Delaney, A. Fortin, C. Julien, L. Mercier, R. Woods, R. Yousef
Prioritizing patients for metabolic and bariatric surgery (MBS) based on their potential postoperative benefits is essential. To examine changes in quality of life (QoL) during the initial postoperative year among patients with diverse eligibility statuses and determine which group experiences greater benefits. Center intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de- Montréal (CIUSSS-NIM), Canada. We categorized patients into 3 groups based on obesity class and the presence of comorbidities: Group 1 (obesity class II without comorbidities, n = 28); Group 2 (obesity class II with comorbidities, n = 36); and Group 3 (obesity class III, n = 460). QoL (Short-Form QoL questionnaire [SF-12]) and anthropometrics were measured at 6 months before, and 6 and 12 months after surgery. Repeated measures mixed models revealed a significant main effect of time ( < .001) and an interaction between time and group for the physical component of QoL ( = .007). These indicated consistent improvements across time in all groups, with the greatest benefits seen in Group 3 relative to Group 1. There were no interactions between time and group for the mental components of QoL ( = .402). There were significant interaction effects for weight and BMI (p’s < .001), with Group 3 losing more weight than Groups 1 or 2. All groups that underwent MBS had improvements in the physical aspects of QoL and weight over time, even those who have traditionally not be considered eligible for MBS (i.e., Group 1). This provides a starting point to explore the importance of not excluding patients due to their weight and comorbidity status and setting comprehensive eligibility criteria encompassing all patients who might benefit from MBS, beyond just weight loss.
根据代谢和减肥手术(MBS)患者术后可能获得的益处确定其优先顺序至关重要。目的:研究不同资格的患者在术后最初一年中生活质量(QoL)的变化,并确定哪一组患者能获得更大的益处。加拿大蒙特利尔北岛健康与社会服务综合大学中心(CIUSSS-NIM)。我们根据肥胖程度和是否存在合并症将患者分为三组:第 1 组(无合并症的 II 类肥胖,n = 28);第 2 组(有合并症的 II 类肥胖,n = 36);第 3 组(III 类肥胖,n = 460)。在手术前 6 个月、手术后 6 个月和 12 个月测量了 QoL(短式 QoL 问卷 [SF-12])和人体测量学指标。重复测量混合模型显示,对于 QoL 的身体部分,时间具有显著的主效应(< .001),时间与组别之间存在交互作用(= .007)。在 QoL 的心理因素方面,时间与组别之间没有交互作用 ( = .402)。体重和体重指数之间存在明显的交互作用(P<0.001),第三组比第一组或第二组减重更多。随着时间的推移,接受心理健康教育的所有组别在身体方面的 QoL 和体重都有所改善,即使是那些传统上被认为不符合心理健康教育条件的组别(即第 1 组)也是如此。这为我们提供了一个起点,以探讨不因体重和并发症状况而将患者排除在外的重要性,以及制定全面的资格标准的重要性,这些标准包括所有可能受益于 MBS 的患者,而不仅仅是体重减轻的患者。
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引用次数: 0
SOARD Category 1 CME Credit Featured Articles, Volume 20, September 2024 SOARD 第 1 类 CME 学分精选文章,第 20 卷,2024 年 9 月
IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-08-27 DOI: 10.1016/j.soard.2024.08.023
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引用次数: 0
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IF 3.5 3区 医学 Q1 SURGERY Pub Date : 2024-08-27 DOI: 10.1016/j.soard.2024.08.024
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Pediatric metabolic and bariatric surgery: indications and preoperative multidisciplinary evaluation 小儿代谢和减肥手术:适应症和术前多学科评估
IF 3.1 3区 医学 Q1 SURGERY Pub Date : 2024-08-27 DOI: 10.1016/j.soard.2024.08.025
Caren Mangarelli M.D. M.S., Gillian Fell M.D., Emily Hobbs M.S. R.D.N. L.D.N., Kelly Walker Lowry Ph.D., Elissa Williams M.S. A.P.R.N.-F.P.A. C.P.N.P.-P.C., Janey S.A. Pratt M.D. F.A.C.S. F.A.S.M.B.S.
The standard of care for pediatric patients with severe obesity considering metabolic and bariatric surgery is a preoperative multidisciplinary evaluation. A multidisciplinary team allows for the efficient use of variable personnel expertise to evaluate, manage, and support a pediatric patient and family through metabolic and bariatric surgery. This review discusses the purpose, recommended team members, patient selection, content, and benefits of the multidisciplinary preoperative evaluation. This evaluation should reduce barriers to care and optimize patient safety and outcomes while taking into consideration the unique developmental needs of this age group.
对于考虑接受代谢和减肥手术的重度肥胖儿科患者,术前多学科评估是护理标准。多学科团队可以有效利用不同人员的专业知识,对儿科患者和家属进行评估、管理和支持,帮助他们完成代谢和减肥手术。本综述讨论了多学科术前评估的目的、推荐团队成员、患者选择、内容和益处。该评估应减少护理障碍,优化患者安全和治疗效果,同时考虑到该年龄组独特的发育需求。
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引用次数: 0
Preoperative nonalcoholic steatohepatitis and resolution of metabolic comorbidities after bariatric surgery 术前非酒精性脂肪性肝炎与减肥手术后代谢合并症的缓解
IF 3.1 3区 医学 Q1 SURGERY Pub Date : 2024-08-24 DOI: 10.1016/j.soard.2024.08.026
Sebastian Storms, Grace H. Oberhoff, Lena Schooren, Andreas Kroh, Alexander Koch, Karl-Peter Rheinwalt, Florian W.R. Vondran, Ulf P. Neumann, Patrick H. Alizai, Sophia M.-T. Schmitz
Most patients undergoing bariatric surgery demonstrate elements of the metabolic syndrome (MetS) and can therefore be diagnosed with metabolically unhealthy obesity (MUO). Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) as hepatic manifestations of the MetS occur in many patients with obesity, but their leverage on postoperative improvement to Metabolic Health (MH), defined as absence of any metabolic comorbidity, remains unclear. The aim of this study was to assess the influence of liver health status, operative procedure, and sex on postoperative switch from a MUO to an MH phenotype. Secondary objective was weight loss to MH. University Hospital, Germany. Patients who underwent either Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) at our obesity surgery center were included in this retrospective study. Liver biopsy was taken and evaluated for presence of NAFLD/NASH. For diagnosis of MH, blood pressure and laboratory values referring to the MetS were assessed preoperatively and at 3, 6, 12, and 24 months’ postoperatively. One hundred thirty-three patients (73% female) with a mean body mass index of 52.0 kg/m and mean age of 43 years were included in this study. A total of 55.6% underwent RYGB and 44.4% underwent SG. NAFLD was found in 51.1% of patients and NASH in 33.8%. All patients were diagnosed MUO at baseline. Postoperatively, 38.3% patients (n = 51) switched to a MH condition. Mean time to MH was 321 days and mean excess body mass index loss to MH was 63.8%. There were no differences regarding liver health status, operative procedure, or sex. Bariatric surgery can resolve MUO independent of liver health status, operative procedure, and sex. However, patients should be closely monitored to ensure sustainable long-term outcomes following the switch to the MH condition.
大多数接受减肥手术的患者都有代谢综合征(MetS)的表现,因此可被诊断为代谢性不健康肥胖(MUO)。非酒精性脂肪性肝病(NAFLD)和非酒精性脂肪性肝炎(NASH)作为代谢综合征的肝脏表现,在许多肥胖症患者中都会出现,但它们对术后代谢健康(MH)(代谢健康的定义是没有任何代谢合并症)改善的影响尚不清楚。本研究旨在评估肝脏健康状况、手术方法和性别对术后从 MUO 转为 MH 表型的影响。次要目标是体重减轻至 MH。德国大学医院。这项回顾性研究的对象包括在本院肥胖症外科中心接受 Roux-en-Y 胃旁路术(RYGB)或袖状胃切除术(SG)的患者。对患者的肝脏进行活检,评估是否存在非酒精性脂肪肝/NASH。为了诊断 MH,在术前和术后 3、6、12 和 24 个月对血压和 MetS 实验室值进行了评估。本研究共纳入 133 名患者(73% 为女性),平均体重指数为 52.0 kg/m,平均年龄为 43 岁。55.6%的患者接受了 RYGB 术,44.4%的患者接受了 SG 术。51.1%的患者患有非酒精性脂肪肝,33.8%的患者患有NASH。所有患者在基线时均被诊断为 MUO。术后,38.3% 的患者(n = 51)转为 MH 状态。转为 MH 的平均时间为 321 天,转为 MH 后的平均体重超标率为 63.8%。肝脏健康状况、手术过程和性别方面没有差异。减肥手术可以解决MUO问题,与肝脏健康状况、手术方法和性别无关。不过,患者应接受密切监测,以确保转为MH状态后的长期疗效。
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引用次数: 0
Conversion of sleeve gastrectomy to Roux-en-Y laparoscopic gastric bypass: a comprehensive 14-year follow-up study on efficacy and outcomes 袖带胃切除术转为 Roux-en-Y 腹腔镜胃旁路术:关于疗效和结果的 14 年综合随访研究
IF 3.1 3区 医学 Q1 SURGERY Pub Date : 2024-08-19 DOI: 10.1016/j.soard.2024.08.021
Yulia Petriuk B.Sc., Shlomi Rayman M.D., Reut El-On M.D., Danit Dayan, Shai Eldar M.D., Adam Abu Abeid M.D., Andrei Keidar M.D.
Failed sleeve gastrectomy (SG), defined by inadequate weight loss or weight regain and by reflux and structural complications, can be treated by a laparoscopic conversion to Roux-en-Y gastric bypass (RYGB). To examine the efficacy and outcomes of conversion surgery over a 14-year follow-up period. Government and private medical centers in university settings. We conducted a cohort study of 58 patients who underwent conversion of SG to RYGB for 2 indications: invalidating reflux or weight recurrence during 2009–2023. Weight dynamics analysis was performed with 2 references of weight: before SG (with intention to treat) and before conversion. At conversion surgery, the mean weight, body mass index (BMI), percentage of excess weight loss (%EWL), and percentage of total weight loss (%TWL) (calculated with intention to treat, from the weight before SG) were 92.2 ± 25.2 kg, 34.3 ± 8.0 kg/m, 55.2% ± 39.9%, and 22.8% ± 15.2%, respectively. Mean nadir weight, BMI, %EWL, and %TWL after conversion (calculated from the weight before SG) were 71.1 ± 18.4 kg, 26.7 ± 5.5 kg/m, 96.5% ± 30.5%, and 40.2% ± 10.6%, respectively. At follow-up, the mean weight, BMI, %EWL, and %TWL (calculated from the weight before SG) were 80.4 ± 17.7 kg, 29.6 ± 5.4 kg/m, 78.9% ± 26.8%, and 33.3% ± 11.2%, respectively. The mean percentages of %EWLio and %TWLio (calculated from the weight before conversion = EWL from index operation) at nadir were 73.2% ± 92.7% and 20.1% ± 12.2% after conversion, respectively, and decreased to 41.9% ± 94.0% and 13.2% ± 15.2% at last follow-up (mean 6.6 yr), respectively. SG to RYGB conversion provides moderate to low complementary weight loss in the short term. By 3–4 years, there is a clear trend toward weight gain.
袖带胃切除术(SG)失败的定义是体重减轻不足或体重反弹以及反流和结构性并发症,可以通过腹腔镜转换为 Roux-en-Y 胃旁路术(RYGB)来治疗。在长达14年的随访期间,研究转换手术的疗效和结果。研究对象为大学环境中的公立和私立医疗中心。我们对 2009-2023 年间因反流失效或体重复发这两种适应症而接受 SG 转 RYGB 手术的 58 名患者进行了队列研究。体重动态分析以两种体重为参考:SG 前(意向治疗)和转换前。转换手术时,平均体重、体重指数(BMI)、超重百分比(%EWL)和总减重百分比(%TWL)(根据手术前的体重,按治疗意向计算)分别为 92.2 ± 25.2 千克、34.3 ± 8.0 千克/米、55.2% ± 39.9% 和 22.8% ± 15.2%。转换后的平均基准体重、BMI、%EWL 和 %TWL(根据 SG 前的体重计算)分别为 71.1 ± 18.4 千克、26.7 ± 5.5 千克/米、96.5% ± 30.5%和 40.2% ± 10.6%。随访时,平均体重、BMI、%EWL 和 %TWL(根据 SG 前的体重计算)分别为 80.4 ± 17.7 千克、29.6 ± 5.4 千克/米、78.9% ± 26.8%和 33.3% ± 11.2%。转换后,最低点时的平均百分比%EWLio和%TWLio(根据转换前体重=指数手术时的EWL计算)分别为73.2%±92.7%和20.1%±12.2%,最后一次随访(平均6.6年)时分别降至41.9%±94.0%和13.2%±15.2%。从 SG 到 RYGB 的转换在短期内可提供中度到低度的补充性体重减轻。3-4 年后,体重增加趋势明显。
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Surgery for Obesity and Related Diseases
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