Pub Date : 2025-09-09DOI: 10.1053/j.sult.2025.09.004
Antonio Eustáquio D. Silva Júnior MD , Pedro Augusto Froldi Vieira MD , Andrei S. Albuquerque MD , Marina S. Fong MD , Lorena Luryann Cartaxo da Silva MD , Igor Rother César de Oliveira MD , Augusto César de Macedo Neto MD , Aley Talans MD , Eduardo O. Pacheco MD , Ulysses S. Torres MD, PhD , Giuseppe D‘Ippolito MD, PhD
Abdominal aortic aneurysm (AAA) is a potentially life-threatening dilation of the aorta, with rupture posing the greatest risk. Surgical management includes both open repair and endovascular aneurysm repair (EVAR), with computed tomography angiography (CTA) serving as the gold standard for preoperative planning, postoperative follow-up, and complication detection. This pictorial review illustrates key imaging features and common complications after AAA repair, including endoleak, graft thrombosis, device migration, and aortoenteric fistulas. It also outlines the imaging appearances of different graft systems (Anaconda™, Ovation™, and snorkel stents) used in EVAR, as well as the classic features of open surgical repair. Given the complexity of graft designs and the spectrum of potential complications, radiologists play a central role in identifying adverse outcomes and ensuring timely clinical intervention. Familiarity with post-treatment imaging findings is essential for accurate interpretation, complication recognition, and improved patient outcomes.
{"title":"Computed Tomographic Angiography in Postoperative Evaluation of Abdominal Aortic Aneurysms: Pearls, Pitfalls, and Complications","authors":"Antonio Eustáquio D. Silva Júnior MD , Pedro Augusto Froldi Vieira MD , Andrei S. Albuquerque MD , Marina S. Fong MD , Lorena Luryann Cartaxo da Silva MD , Igor Rother César de Oliveira MD , Augusto César de Macedo Neto MD , Aley Talans MD , Eduardo O. Pacheco MD , Ulysses S. Torres MD, PhD , Giuseppe D‘Ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.004","DOIUrl":"10.1053/j.sult.2025.09.004","url":null,"abstract":"<div><div>Abdominal aortic aneurysm (AAA) is a potentially life-threatening dilation of the aorta, with rupture posing the greatest risk. Surgical management includes both open repair and endovascular aneurysm repair (EVAR), with computed tomography angiography (CTA) serving as the gold standard for preoperative planning, postoperative follow-up, and complication detection. This pictorial review illustrates key imaging features and common complications after AAA repair, including endoleak, graft thrombosis, device migration, and aortoenteric fistulas. It also outlines the imaging appearances of different graft systems (Anaconda™, Ovation™, and snorkel stents) used in EVAR, as well as the classic features of open surgical repair. Given the complexity of graft designs and the spectrum of potential complications, radiologists play a central role in identifying adverse outcomes and ensuring timely clinical intervention. Familiarity with post-treatment imaging findings is essential for accurate interpretation, complication recognition, and improved patient outcomes.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 450-459"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare tumor, considered a pre-invasive lesion derived from the biliary epithelium. Although it shares similarities with intraductal papillary mucinous neoplasm (IPMN) of the pancreas, only one-third of patients present with mucin hypersecretion. The World Health Organization (WHO) formalized the description of IPNB in 2010 as a "non-invasive biliary papillary or villous neoplasm covering delicate fibrovascular stalks in dilated bile ducts." Despite advancements, literature still lacks multicenter studies on its progression and prognosis. This article reviews the clinical, epidemiological, and radiological features of IPNB, highlighting its recent classifications and key findings, contributing to appropriate management based on a literature review and case examples.
{"title":"Intraductal Papillary Neoplasm of the Bile Duct: Simplifying Findings","authors":"Nathália Gonçalves Dias MD , Julia de Toledo Mendes MD , Bruna Andreucci Kozlowski MD , Daniella Braz Parente MD, PhD , Daniel Lahan Martins MD, PhD , Thiago Franchi Nunes MD, PhD , Matheus Menezes Gomes MD , Aley Talans MD , Eduardo Oliveira Pacheco MD , Ulysses S. Torres MD, PhD , Guiseppe D'ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.005","DOIUrl":"10.1053/j.sult.2025.09.005","url":null,"abstract":"<div><div>Intraductal papillary neoplasm of the bile duct (IPNB) is a rare tumor, considered a pre-invasive lesion derived from the biliary epithelium. Although it shares similarities with intraductal papillary mucinous neoplasm (IPMN) of the pancreas, only one-third of patients present with mucin hypersecretion. The World Health Organization (WHO) formalized the description of IPNB in 2010 as a \"non-invasive biliary papillary or villous neoplasm covering delicate fibrovascular stalks in dilated bile ducts.\" Despite advancements, literature still lacks multicenter studies on its progression and prognosis. This article reviews the clinical, epidemiological, and radiological features of IPNB, highlighting its recent classifications and key findings, contributing to appropriate management based on a literature review and case examples.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 415-427"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-09DOI: 10.1053/j.sult.2025.09.007
Ana Paula Bavaresco MD , Ulysses S. Torres MD, PhD , Mayara S. Cruz MD , Vitor V.C. Machado MD , Cynthia L.P. Borborema MD , Giovanna S. Torre MD , Jhonata Soares Da Silva MD , Tulio A. Kawai MD , Gustavo R.A. Focchi MD , Eduardo O. Pacheco MD , Aley Talans MD , Daniel Bekhor MD , Ana Paula C. Moura MD , Lucas R. Torres MD , Giuseppe D'Ippolito MD, PhD
Gynecologic neuroendocrine tumors (NETs) are rare, highly aggressive malignancies that can arise in any part of the female reproductive tract, most often in the cervix. Their clinical course is marked by rapid progression, early spread, and limited treatment options, making prompt recognition essential. Diagnosis depends on histopathologic evaluation, supported by immunohistochemistry, while imaging (particularly magnetic resonance) plays a central role in staging, treatment planning, and follow-up, despite often nonspecific appearances. This narrative pictorial review integrates current understanding of histopathologic classification, clinical presentation, and imaging characteristics across modalities, highlighting features that may raise suspicion for these tumors and common diagnostic pitfalls. Representative cases illustrate the spectrum of disease, from localized lesions to widely metastatic presentations. Management typically involves multimodal strategies, with growing interest in targeted and immune-based therapies. By combining clinical, pathologic, and radiologic perspectives, this review aims to enhance awareness and support more timely, accurate diagnosis of these challenging neoplasms.
{"title":"Imaging of Gynecologic Neuroendocrine Tumors: A Case-Based Pictorial Essay","authors":"Ana Paula Bavaresco MD , Ulysses S. Torres MD, PhD , Mayara S. Cruz MD , Vitor V.C. Machado MD , Cynthia L.P. Borborema MD , Giovanna S. Torre MD , Jhonata Soares Da Silva MD , Tulio A. Kawai MD , Gustavo R.A. Focchi MD , Eduardo O. Pacheco MD , Aley Talans MD , Daniel Bekhor MD , Ana Paula C. Moura MD , Lucas R. Torres MD , Giuseppe D'Ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.007","DOIUrl":"10.1053/j.sult.2025.09.007","url":null,"abstract":"<div><div>Gynecologic neuroendocrine tumors (NETs) are rare, highly aggressive malignancies that can arise in any part of the female reproductive tract, most often in the cervix. Their clinical course is marked by rapid progression, early spread, and limited treatment options, making prompt recognition essential. Diagnosis depends on histopathologic evaluation, supported by immunohistochemistry, while imaging (particularly magnetic resonance) plays a central role in staging, treatment planning, and follow-up, despite often nonspecific appearances. This narrative pictorial review integrates current understanding of histopathologic classification, clinical presentation, and imaging characteristics across modalities, highlighting features that may raise suspicion for these tumors and common diagnostic pitfalls. Representative cases illustrate the spectrum of disease, from localized lesions to widely metastatic presentations. Management typically involves multimodal strategies, with growing interest in targeted and immune-based therapies. By combining clinical, pathologic, and radiologic perspectives, this review aims to enhance awareness and support more timely, accurate diagnosis of these challenging neoplasms.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 440-449"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-08DOI: 10.1053/j.sult.2025.09.002
Suryansh Bajaj MD , Frank Chen MD , Jordan LeGout MD , Joseph Cernigliaro MD , Gitanjali Bajaj MD (Associate Professor) , Shweta Bhatt MBBS, MD
Classic radiological signs in imaging serve as visual clues that aid in narrowing the differential diagnosis and enhancing diagnostic confidence. This review article highlights key imaging signs encountered in hepatic pathology across multiple modalities including ultrasound, CT, and MRI. We explore some of the characteristic signs associated with hepatic neoplastic, infectious, vascular lesions, anatomicvariations and miscellaneous conditions, discussing their pathophysiology, diagnosticutility and clinical relevance. By revisiting these classic signs, radiologists can reinforce pattern recognition skills essential for accurate interpretation. This article aims to serve as a practicalreference and educational resource for radiologists, trainees and clinicians involved in hepatic imaging.
{"title":"Classic Imaging Signs in Hepatobiliary Radiology: A Multimodality Review","authors":"Suryansh Bajaj MD , Frank Chen MD , Jordan LeGout MD , Joseph Cernigliaro MD , Gitanjali Bajaj MD (Associate Professor) , Shweta Bhatt MBBS, MD","doi":"10.1053/j.sult.2025.09.002","DOIUrl":"10.1053/j.sult.2025.09.002","url":null,"abstract":"<div><div>Classic radiological signs in imaging serve as visual clues that aid in narrowing the differential diagnosis and enhancing diagnostic confidence. This review article highlights key imaging signs encountered in hepatic pathology across multiple modalities including ultrasound, CT, and MRI. We explore some of the characteristic signs associated with hepatic neoplastic, infectious, vascular lesions, anatomicvariations and miscellaneous conditions, discussing their pathophysiology, diagnosticutility and clinical relevance. By revisiting these classic signs, radiologists can reinforce pattern recognition skills essential for accurate interpretation. This article aims to serve as a practicalreference and educational resource for radiologists, trainees and clinicians involved in hepatic imaging.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 428-439"},"PeriodicalIF":1.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-08DOI: 10.1053/j.sult.2025.09.003
Matheus M. Gomes MD , Gabriel T. Lingiardi MD , Cynthia L.P. Borborema MD , Eduardo O. Pacheco MD , Daniella B. Parente MD, PhD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD
The periportal region is a complex anatomical area that includes important structures such as the hepatic artery, bile ducts, lymphatics, and nerves. Due to its rich architecture, diagnosing lesions in this space presents a significant challenge for radiologists. Various pathological conditions can affect this region, ranging from vascular and lymphatic diseases to infectious and malignant lesions. This article explores the main periportal conditions through various imaging methods, including ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance cholangiopancreatography (MRCP). Therefore, understanding specific radiological manifestations is essential for differentiating clinical conditions and guiding appropriate treatment.
{"title":"Periportal Space Lesions: Imaging Spectrum and Differential Diagnosis","authors":"Matheus M. Gomes MD , Gabriel T. Lingiardi MD , Cynthia L.P. Borborema MD , Eduardo O. Pacheco MD , Daniella B. Parente MD, PhD , Ulysses S. Torres MD, PhD , Giuseppe D’Ippolito MD, PhD","doi":"10.1053/j.sult.2025.09.003","DOIUrl":"10.1053/j.sult.2025.09.003","url":null,"abstract":"<div><div>The periportal region is a complex anatomical area that includes important structures such as the hepatic artery, bile ducts, lymphatics, and nerves. Due to its rich architecture, diagnosing lesions in this space presents a significant challenge for radiologists. Various pathological conditions can affect this region, ranging from vascular and lymphatic diseases to infectious and malignant lesions. This article explores the main periportal conditions through various imaging methods, including ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance cholangiopancreatography (MRCP). Therefore, understanding specific radiological manifestations is essential for differentiating clinical conditions and guiding appropriate treatment.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 6","pages":"Pages 399-414"},"PeriodicalIF":1.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-22DOI: 10.1053/j.sult.2025.07.002
Ryoko Egashira MD, PhD , Daisuke Yamada MD, PhD , Joseph Jacob MD, PhD
This review summarizes the 3 components of the pulmonary lymphatic system: lymphatic channels, bronchus-associated lymphoid tissue (BALT), and intrapulmonary lymph nodes. Lymphatic vessels are distributed within the bronchovascular bundles, in the interlobular septa and visceral pleura, and around small pulmonary arteries and veins within the secondary pulmonary lobules. Normally invisible on CT, they may appear with lymphatic dilation or disease spreading via lymphatic routes. BALT is usually absent histologically in healthy lungs but may be visible in smokers or autoimmune conditions. Intrapulmonary lymph nodes present as well-defined peripheral nodules in the lower lobes, often with linear opacities.
{"title":"Anatomy of Pulmonary Lymphatics and Lymphoid Tissues","authors":"Ryoko Egashira MD, PhD , Daisuke Yamada MD, PhD , Joseph Jacob MD, PhD","doi":"10.1053/j.sult.2025.07.002","DOIUrl":"10.1053/j.sult.2025.07.002","url":null,"abstract":"<div><div>This review summarizes the 3 components of the pulmonary lymphatic system: lymphatic channels, bronchus-associated lymphoid tissue (BALT), and intrapulmonary lymph nodes. Lymphatic vessels are distributed within the bronchovascular bundles, in the interlobular septa and visceral pleura, and around small pulmonary arteries and veins within the secondary pulmonary lobules. Normally invisible on CT, they may appear with lymphatic dilation or disease spreading via lymphatic routes. BALT is usually absent histologically in healthy lungs but may be visible in smokers or autoimmune conditions. Intrapulmonary lymph nodes present as well-defined peripheral nodules in the lower lobes, often with linear opacities.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 4","pages":"Pages 266-271"},"PeriodicalIF":1.9,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-05DOI: 10.1053/j.sult.2025.07.001
Takeshi Johkoh MD, PhD
{"title":"Letter From the Guest Editor","authors":"Takeshi Johkoh MD, PhD","doi":"10.1053/j.sult.2025.07.001","DOIUrl":"10.1053/j.sult.2025.07.001","url":null,"abstract":"","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 4","pages":"Page 265"},"PeriodicalIF":1.9,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1053/j.sult.2025.06.005
Yoshiaki Zaizen , Junya Fukuoka MD, PhD
Pulmonary lymphoproliferative disorders (PLDs) are a diverse group of rare entities characterized by abnormal lymphoid proliferation within the lung. These include both benign and malignant processes and are classified into five categories in the 2021 WHO Classification of Thoracic Tumors: benign hyperplastic disorders, primary pulmonary neoplasms, secondary involvement of the lung, posttransplant lymphoproliferative disorders, and histiocytic neoplasms. Diagnosing PLDs is often challenging due to their histological similarity to other lymphocyte-rich interstitial lung diseases, including cellular nonspecific interstitial pneumonia (NSIP) and hypersensitivity pneumonitis. A multidisciplinary approach integrating clinical, radiologic, and pathological information is essential to reach an accurate diagnosis. This review focuses on the detailed pathological features of PLDs, particularly benign hyperplastic disorders and primary pulmonary neoplasms. It emphasizes the differential diagnosis and highlights distinguishing characteristics among key subtypes, including lymphoid interstitial pneumonia, follicular bronchiolitis, nodular lymphoid hyperplasia, Castleman disease, IgG4-related disease, and primary pulmonary lymphomas such as MALT lymphoma, diffuse large B-cell lymphoma, and lymphomatoid granulomatosis. Special attention is paid to morphological patterns, immunophenotypes, and diagnostic challenges encountered with small biopsies. Given the broad differential diagnosis and potential overlap with infectious, autoimmune, or immunodeficiency-related conditions, careful clinicopathological correlation remains the cornerstone of accurate classification and appropriate management. This review aims to enhance diagnostic clarity and support effective interdisciplinary evaluation of suspected PLD cases.
{"title":"Pathologic Findings of Pulmonary Lymphoproliferative Disorders","authors":"Yoshiaki Zaizen , Junya Fukuoka MD, PhD","doi":"10.1053/j.sult.2025.06.005","DOIUrl":"10.1053/j.sult.2025.06.005","url":null,"abstract":"<div><div>Pulmonary lymphoproliferative disorders (PLDs) are a diverse group of rare entities characterized by abnormal lymphoid proliferation within the lung. These include both benign and malignant processes and are classified into five categories in the 2021 WHO Classification of Thoracic Tumors: benign hyperplastic disorders, primary pulmonary neoplasms, secondary involvement of the lung, posttransplant lymphoproliferative disorders, and histiocytic neoplasms. Diagnosing PLDs is often challenging due to their histological similarity to other lymphocyte-rich interstitial lung diseases, including cellular nonspecific interstitial pneumonia (NSIP) and hypersensitivity pneumonitis. A multidisciplinary approach integrating clinical, radiologic, and pathological information is essential to reach an accurate diagnosis. This review focuses on the detailed pathological features of PLDs, particularly benign hyperplastic disorders and primary pulmonary neoplasms. It emphasizes the differential diagnosis and highlights distinguishing characteristics among key subtypes, including lymphoid interstitial pneumonia, follicular bronchiolitis, nodular lymphoid hyperplasia, Castleman disease, IgG4-related disease, and primary pulmonary lymphomas such as MALT lymphoma, diffuse large B-cell lymphoma, and lymphomatoid granulomatosis. Special attention is paid to morphological patterns, immunophenotypes, and diagnostic challenges encountered with small biopsies. Given the broad differential diagnosis and potential overlap with infectious, autoimmune, or immunodeficiency-related conditions, careful clinicopathological correlation remains the cornerstone of accurate classification and appropriate management. This review aims to enhance diagnostic clarity and support effective interdisciplinary evaluation of suspected PLD cases.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 4","pages":"Pages 272-282"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarcoidosis is a systemic granulomatous disorder of unknown cause, histopathologically characterized by the presence of non-caseating epithelioid-cell granulomas involving multiple organs, and most commonly involves the lungs and mediastinal and bilateral hilar lymph nodes (and the lymphatic systems). Although a definitive diagnosis relies on clinical and histopathological analysis, imaging plays a crucial role in early detection, lesion characterization, disease staging, and treatment response. This review focuses on imaging of pulmonary sarcoidosis, including histopathology, chest radiographic staging, and CT of mediastinal/hilar lymphadenopathy and parenchymal abnormalities (perilymphatic nodules, ground-glass opacity, coalescent or aggregate nodules, parenchymal fibrotic changes, and airway lesions), in addition to pulmonary hypertension and cardiac sarcoidosis. Differential diagnosis for imaging of diseases involving pulmonary lymphatics, particularly lymphangitic spread of carcinoma, is also demonstrated.
{"title":"Imaging of Diseases Involving Pulmonary Lymphatics: Focus on Pulmonary Sarcoidosis","authors":"Kiminori Fujimoto MD, PhD , Tomonori Chikasue MD , Yoshiaki Zaizen MD, PhD , Akiko Sumi MD, PhD , Saeko Tokisawa MD, PhD","doi":"10.1053/j.sult.2025.06.007","DOIUrl":"10.1053/j.sult.2025.06.007","url":null,"abstract":"<div><div>Sarcoidosis is a systemic granulomatous disorder of unknown cause, histopathologically characterized by the presence of non-caseating epithelioid-cell granulomas involving multiple organs, and most commonly involves the lungs and mediastinal and bilateral hilar lymph nodes (and the lymphatic systems). Although a definitive diagnosis relies on clinical and histopathological analysis, imaging plays a crucial role in early detection, lesion characterization, disease staging, and treatment response. This review focuses on imaging of pulmonary sarcoidosis, including histopathology, chest radiographic staging, and CT of mediastinal/hilar lymphadenopathy and parenchymal abnormalities (perilymphatic nodules, ground-glass opacity, coalescent or aggregate nodules, parenchymal fibrotic changes, and airway lesions), in addition to pulmonary hypertension and cardiac sarcoidosis. Differential diagnosis for imaging of diseases involving pulmonary lymphatics, particularly lymphangitic spread of carcinoma, is also demonstrated.</div></div>","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 4","pages":"Pages 325-342"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-26DOI: 10.1053/j.sult.2025.06.006
Vasilios Tzilas MD, PhD , Jay H. Ryu MD
{"title":"Clinical Features of Pulmonary Lymphoproliferative Disorders","authors":"Vasilios Tzilas MD, PhD , Jay H. Ryu MD","doi":"10.1053/j.sult.2025.06.006","DOIUrl":"10.1053/j.sult.2025.06.006","url":null,"abstract":"","PeriodicalId":49541,"journal":{"name":"Seminars in Ultrasound Ct and Mri","volume":"46 4","pages":"Pages 283-295"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}