Pub Date : 2026-01-07DOI: 10.1016/j.puhe.2025.106107
Emerson Augusto Baptista , Claudio Alberto Dávila Cervantes
Objectives
Homicide remains one of the most pressing public health challenges in Mexico, with mortality rates rising dramatically since 2006 in the context of escalating organized crime and militarized security strategies. Understanding its spatial distribution and structural determinants is essential for designing prevention strategies that address inequality, urbanization, and marginalization.
Study design
We employed a Spatial Zero-Inflated Poisson (S-ZIP) model to analyze homicide mortality across Mexico's municipalities.
Methods
We analyzed homicide mortality across 2469 Mexican municipalities in 2020 using data from the National Institute of Statistics and Geography (ICD-10 codes X85-Y09, Y87.1) and census-derived socioeconomic indicators. To account for excess zeros, overdispersion, and spatial dependence, we applied a Spatial Zero-Inflated Poisson (S-ZIP) model. The explanatory variables included the municipal marginalization index, the proportion of the urban population, and the Gini coefficient of income inequality. Spatial dependence was modeled through Besag-York-Mollié random effects.
Results
Results from the Spatial Zero-Inflated Poisson model showed significant associations between the explanatory variables and homicide mortality, with urbanization and income inequality increasing the risk and reducing the probability of zero homicides. While all covariates were statistically significant, the effect of marginalization partly reflected unmodeled spatial patterns. The model further estimated that nearly one-quarter of Mexican municipalities had a structural zero probability of homicides. Overall, the findings highlight substantial territorial heterogeneity in homicide mortality across the country.
Conclusions
Homicide mortality in Mexico is shaped by structural inequalities and spatial clustering. By framing lethal violence as a public health issue, our findings support geographically targeted policies that reduce inequality, address risks linked to urbanization and strengthen institutional and community resilience.
目标谋杀仍然是墨西哥最紧迫的公共卫生挑战之一,自2006年以来,在有组织犯罪不断升级和军事化安全战略的背景下,死亡率急剧上升。了解其空间分布和结构决定因素对于设计解决不平等、城市化和边缘化问题的预防战略至关重要。研究设计我们采用空间零膨胀泊松(S-ZIP)模型来分析墨西哥各城市的他杀死亡率。方法:我们使用国家统计和地理研究所(ICD-10代码X85-Y09, Y87.1)的数据和人口普查得出的社会经济指标,分析了2020年墨西哥2469个城市的杀人死亡率。为了解释多余的零、过度分散和空间依赖性,我们应用了空间零膨胀泊松(S-ZIP)模型。解释变量包括城市边缘化指数、城市人口比例和收入不平等的基尼系数。空间依赖性通过besag - york - molli随机效应建模。结果空间零膨胀泊松模型的结果显示,解释变量与凶杀死亡率之间存在显著相关性,城市化和收入不平等增加了零凶杀的风险,降低了零凶杀的概率。虽然所有协变量都具有统计学意义,但边缘化的影响部分反映了未建模的空间格局。该模型进一步估计,近四分之一的墨西哥城市发生凶杀案的结构性概率为零。总的来说,研究结果强调了全国各地杀人死亡率的巨大地域差异。结论墨西哥的杀人死亡率受结构不平等和空间聚类的影响。通过将致命暴力视为一个公共卫生问题,我们的研究结果支持有地域针对性的政策,以减少不平等,解决与城市化相关的风险,并加强机构和社区的复原力。
{"title":"Spatial zero-inflated poisson analysis of homicide mortality in Mexican municipalities, 2020","authors":"Emerson Augusto Baptista , Claudio Alberto Dávila Cervantes","doi":"10.1016/j.puhe.2025.106107","DOIUrl":"10.1016/j.puhe.2025.106107","url":null,"abstract":"<div><h3>Objectives</h3><div>Homicide remains one of the most pressing public health challenges in Mexico, with mortality rates rising dramatically since 2006 in the context of escalating organized crime and militarized security strategies. Understanding its spatial distribution and structural determinants is essential for designing prevention strategies that address inequality, urbanization, and marginalization.</div></div><div><h3>Study design</h3><div>We employed a Spatial Zero-Inflated Poisson (S-ZIP) model to analyze homicide mortality across Mexico's municipalities.</div></div><div><h3>Methods</h3><div>We analyzed homicide mortality across 2469 Mexican municipalities in 2020 using data from the National Institute of Statistics and Geography (ICD-10 codes X85-Y09, Y87.1) and census-derived socioeconomic indicators. To account for excess zeros, overdispersion, and spatial dependence, we applied a Spatial Zero-Inflated Poisson (S-ZIP) model. The explanatory variables included the municipal marginalization index, the proportion of the urban population, and the Gini coefficient of income inequality. Spatial dependence was modeled through Besag-York-Mollié random effects.</div></div><div><h3>Results</h3><div>Results from the Spatial Zero-Inflated Poisson model showed significant associations between the explanatory variables and homicide mortality, with urbanization and income inequality increasing the risk and reducing the probability of zero homicides. While all covariates were statistically significant, the effect of marginalization partly reflected unmodeled spatial patterns. The model further estimated that nearly one-quarter of Mexican municipalities had a structural zero probability of homicides. Overall, the findings highlight substantial territorial heterogeneity in homicide mortality across the country.</div></div><div><h3>Conclusions</h3><div>Homicide mortality in Mexico is shaped by structural inequalities and spatial clustering. By framing lethal violence as a public health issue, our findings support geographically targeted policies that reduce inequality, address risks linked to urbanization and strengthen institutional and community resilience.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106107"},"PeriodicalIF":3.2,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-07DOI: 10.1016/j.puhe.2025.106114
Bing Wang , Prabha Andraweera , Gang Chen , Jason J. Ong , Zohra Lassi , Helen Marshall
Objectives
Respiratory Syncytial Virus (RSV) is the leading cause of bronchiolitis and pneumonia in infants and can lead to fatal respiratory distress, especially in very young infants. New maternal RSV vaccines and infant monoclonal antibodies are now available. This study aims to understand RSV vaccine attitudes in Australian pregnant women.
Study design
The cross-sectional online survey employed a discrete choice experiment (DCE) design to quantify trade-offs and investigate decision-making patterns among pregnant women regarding the maternal RSV vaccine. A mixed-methods approach was used, with results from focus group discussions informing the development of the DCE survey.
Methods
Any pregnant women aged ≥18 years in Australia were eligible to participate in the survey. During the survey, respondents were asked to choose between hypothetical scenarios, or optout option. Survey data were analysed using mixed logit and latent class models.
Results
In total, 440 pregnant women participated and demonstrated a strong preference for a free RSV maternal vaccine with a lower risk of serious side effects and higher vaccine effectiveness. Latent class analysis revealed two distinct preference groups: “accepters/deliberators” and “rejecters”. Compared to rejecters (31.7 %), accepters/deliberators (68.3 %) were more likely to be older, haver high household income and had received a pertussis vaccine, and were less likely to receive an influenza vaccine. Incentives to encourage vaccination were not supported by either group. Among rejecters, cost did not influence their vaccine preference, but text message reminders were more preferred. In contrast to accepters/deliberators, rejecters expressed a strong dislike for video advertisements. Participants showed a significantly higher preference for RSV maternal vaccination (54.8 %) versus infant monoclonal antibody injection (16.8 %) in a general preference question (p < 0.001).
Conclusions
Maternal RSV vaccination at no cost was generally well received and preferred by pregnant women in this study, though preferences for promotion strategies varied.
{"title":"Respiratory syncytial virus (RSV) vaccine choices during pregnancy","authors":"Bing Wang , Prabha Andraweera , Gang Chen , Jason J. Ong , Zohra Lassi , Helen Marshall","doi":"10.1016/j.puhe.2025.106114","DOIUrl":"10.1016/j.puhe.2025.106114","url":null,"abstract":"<div><h3>Objectives</h3><div>Respiratory Syncytial Virus (RSV) is the leading cause of bronchiolitis and pneumonia in infants and can lead to fatal respiratory distress, especially in very young infants. New maternal RSV vaccines and infant monoclonal antibodies are now available. This study aims to understand RSV vaccine attitudes in Australian pregnant women.</div></div><div><h3>Study design</h3><div>The cross-sectional online survey employed a discrete choice experiment (DCE) design to quantify trade-offs and investigate decision-making patterns among pregnant women regarding the maternal RSV vaccine. A mixed-methods approach was used, with results from focus group discussions informing the development of the DCE survey.</div></div><div><h3>Methods</h3><div>Any pregnant women aged ≥18 years in Australia were eligible to participate in the survey. During the survey, respondents were asked to choose between hypothetical scenarios, or optout option. Survey data were analysed using mixed logit and latent class models.</div></div><div><h3>Results</h3><div>In total, 440 pregnant women participated and demonstrated a strong preference for a free RSV maternal vaccine with a lower risk of serious side effects and higher vaccine effectiveness. Latent class analysis revealed two distinct preference groups: “accepters/deliberators” and “rejecters”. Compared to rejecters (31.7 %), accepters/deliberators (68.3 %) were more likely to be older, haver high household income and had received a pertussis vaccine, and were less likely to receive an influenza vaccine. Incentives to encourage vaccination were not supported by either group. Among rejecters, cost did not influence their vaccine preference, but text message reminders were more preferred. In contrast to accepters/deliberators, rejecters expressed a strong dislike for video advertisements. Participants showed a significantly higher preference for RSV maternal vaccination (54.8 %) versus infant monoclonal antibody injection (16.8 %) in a general preference question (p < 0.001).</div></div><div><h3>Conclusions</h3><div>Maternal RSV vaccination at no cost was generally well received and preferred by pregnant women in this study, though preferences for promotion strategies varied.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106114"},"PeriodicalIF":3.2,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.puhe.2025.106060
Muslim Abbas Syed , Mohamed Ahmed Syed , Andrew C.K. Lee
Balancing finite resources with rising demand remains a universal challenge for healthcare systems. Organizational decision making is increasingly shaped by cost-efficiency, yet efficiency is often mistakenly equated with effectiveness. Systems may reduce costs and waiting times but still fail to improve individual health outcomes, risking population health in pursuit of financial balance. In England, efforts to curb the ballooning health budget include the dissolution of NHS England and its merger with the Department of Health and Social Care. These reforms, while aimed at streamlining services, risk eroding organizational memory—knowledge embedded in people, processes, and practices. Organizational memory guides current decisions, prevents repetition of failed measures, and supports innovation. Its loss, especially through staff attrition and restructuring, may paradoxically undermine the very improvements these reforms seek to achieve. Singapore's healthcare system offers a counterfactual example, demonstrating how effective use of organizational memory—through electronic health records, regionalized clusters, and preventive care initiatives—can lead to adaptive, efficient, and high-quality care. Gulf Cooperation Council countries, including Qatar, are adopting similar strategies, using rich patient data to inform research and policy. Organizational memory is not an afterthought but a foundational asset. As healthcare systems evolve under financial, technological, and patient-centered pressures, preserving and leveraging organizational memory is essential. Reforms must be designed not only to improve efficiency but also to sustain effectiveness and ensure long-term improvements in patient outcomes.
{"title":"Avoiding corporate amnesia in health systems – the need for organizational memory","authors":"Muslim Abbas Syed , Mohamed Ahmed Syed , Andrew C.K. Lee","doi":"10.1016/j.puhe.2025.106060","DOIUrl":"10.1016/j.puhe.2025.106060","url":null,"abstract":"<div><div>Balancing finite resources with rising demand remains a universal challenge for healthcare systems. Organizational decision making is increasingly shaped by cost-efficiency, yet efficiency is often mistakenly equated with effectiveness. Systems may reduce costs and waiting times but still fail to improve individual health outcomes, risking population health in pursuit of financial balance. In England, efforts to curb the ballooning health budget include the dissolution of NHS England and its merger with the Department of Health and Social Care. These reforms, while aimed at streamlining services, risk eroding organizational memory—knowledge embedded in people, processes, and practices. Organizational memory guides current decisions, prevents repetition of failed measures, and supports innovation. Its loss, especially through staff attrition and restructuring, may paradoxically undermine the very improvements these reforms seek to achieve. Singapore's healthcare system offers a counterfactual example, demonstrating how effective use of organizational memory—through electronic health records, regionalized clusters, and preventive care initiatives—can lead to adaptive, efficient, and high-quality care. Gulf Cooperation Council countries, including Qatar, are adopting similar strategies, using rich patient data to inform research and policy. Organizational memory is not an afterthought but a foundational asset. As healthcare systems evolve under financial, technological, and patient-centered pressures, preserving and leveraging organizational memory is essential. Reforms must be designed not only to improve efficiency but also to sustain effectiveness and ensure long-term improvements in patient outcomes.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"250 ","pages":"Article 106060"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.puhe.2025.105988
Sebastien Chastin , Maïté Verloigne , Maria Giné-Garriga
{"title":"Establishing the ‘Science of Co-creation’ for public health","authors":"Sebastien Chastin , Maïté Verloigne , Maria Giné-Garriga","doi":"10.1016/j.puhe.2025.105988","DOIUrl":"10.1016/j.puhe.2025.105988","url":null,"abstract":"","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"250 ","pages":"Article 105988"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-31DOI: 10.1016/j.puhe.2025.106113
Emma Grundtvig Gram , Volkert Siersma , John Brandt Brodersen , Dagny Ros Nicolaisdottir , Jessica á Rogvi
Objectives
This study examines the association between participation in colorectal cancer screening and subsequent secondary healthcare use.
Study design
A prospective cohort study.
Methods
Exposure was based on a quasi-randomised screening implementation, with a 24-month follow-up. Outcomes included out-of-hospital specialist visits, hospitalisation, outpatient clinic visits, emergency room visits, colonoscopies and sigmoidoscopies, and prescription drugs. We employed a two-step model to estimate the relative risk and incidence-rate ratio of healthcare use, adjusted for baseline healthcare usage over the past decade and relevant socioeconomic factors. The results were stratified by screening results.
Results
Individuals with negative screenings were more likely to consult out-of-hospital specialists compared with a screening-naive control group. All screening groups had higher risk of hospitalisation, higher risk of using outpatient and emergency services, and higher risk of redeeming prescription drugs compared with the control group. Among those that used the respective services, it did not seem that screening groups had more visits or uses compared with the control group.
Conclusions
We observed an increase in healthcare use following colorectal cancer screening, suggesting that screening participants are referred more to secondary healthcare services.
{"title":"The impact of colorectal cancer screening on healthcare use: A prospective cohort study with quasi-randomised screening invitation","authors":"Emma Grundtvig Gram , Volkert Siersma , John Brandt Brodersen , Dagny Ros Nicolaisdottir , Jessica á Rogvi","doi":"10.1016/j.puhe.2025.106113","DOIUrl":"10.1016/j.puhe.2025.106113","url":null,"abstract":"<div><h3>Objectives</h3><div>This study examines the association between participation in colorectal cancer screening and subsequent secondary healthcare use.</div></div><div><h3>Study design</h3><div>A prospective cohort study.</div></div><div><h3>Methods</h3><div>Exposure was based on a quasi-randomised screening implementation, with a 24-month follow-up. Outcomes included out-of-hospital specialist visits, hospitalisation, outpatient clinic visits, emergency room visits, colonoscopies and sigmoidoscopies, and prescription drugs. We employed a two-step model to estimate the relative risk and incidence-rate ratio of healthcare use, adjusted for baseline healthcare usage over the past decade and relevant socioeconomic factors. The results were stratified by screening results.</div></div><div><h3>Results</h3><div>Individuals with negative screenings were more likely to consult out-of-hospital specialists compared with a screening-naive control group. All screening groups had higher risk of hospitalisation, higher risk of using outpatient and emergency services, and higher risk of redeeming prescription drugs compared with the control group. Among those that used the respective services, it did not seem that screening groups had more visits or uses compared with the control group.</div></div><div><h3>Conclusions</h3><div>We observed an increase in healthcare use following colorectal cancer screening, suggesting that screening participants are referred more to secondary healthcare services.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106113"},"PeriodicalIF":3.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-31DOI: 10.1016/j.puhe.2025.106115
Yuansen Ma , Xiaomei Wu , Yu Sun , Mouqian Wu , Qihui Tian , Jiahui Tian , Duo Xu , Meixi Gong , Xuanbing Li , Yefu Liu , Bo Zhu
Objectives
Prolonged sedentary behavior increases colorectal cancer (CRC) risk, while physical activity (PA) may reduce it. However, whether PA can mitigate the adverse effects of sedentary time remains unclear. This study examines whether PA modifies the association between sedentary time and CRC risk, and vice versa, and estimates the joint associations of PA and sedentary time with CRC risk using two surveys.
Study design
Cross-sectional study.
Methods
Data were drawn from NHANES and KNHANES. PA and sedentary time were assessed using the Global Physical Activity Questionnaire. Logistic regression with stratified analyses and restricted cubic splines was used to assess associations. Racial subgroup analyses were also performed.
Results
Among 338 CRC cases (NHANES: n = 103, weighted population: 1,282,253; KNHANES: n = 235, weighted population: 190,811), sedentary time greater than 8 h/day (reference 0-<4 h/day) was associated with CRC risk only among those with inactive PA (<600 MET-min/week) (NHANES: OR = 3.37, 95 % CI: 1.03–11.05; KNHANES: OR = 1.47, 95 % CI: 0.82–3.46). Black and Asian individuals with inactive PA showed a higher CRC risk associated with higher sedentary time. Among participants with >8 h sedentary time, higher PA levels (≥2000 MET-min/week) were associated with significantly reduced CRC risk in both datasets (NHANES: 2000–3999 MET-min/week, OR = 0.13, 95 % CI: 0.02–0.77; ≥4000 MET-min/week, OR = 0.08, 95 % CI: 0.01–0.75; KNHANES: 2000–3999 MET-min/week, OR = 0.36, 95 % CI: 0.11–0.98; ≥4000 MET-min/week, OR = 0.33, 95 % CI: 0.04–2.39). Joint analyses showed that individuals with active PA and low sedentary time were associated with reduced CRC risk.
Conclusions
Sedentary time was associated with higher CRC risk but only in individuals with inactive PA (<600 MET-min/week). Higher levels of PA showed greater benefit for CRC risk in those with sedentary time >8 h/day. The combination of active PA and low sedentary time was strongly associated with reduced CRC risk.
长期久坐行为会增加结直肠癌(CRC)的风险,而体育活动(PA)可能会降低这种风险。然而,PA是否能减轻久坐时间的不利影响尚不清楚。本研究考察了PA是否改变了久坐时间与结直肠癌风险之间的关系,反之亦然,并通过两项调查估计了PA和久坐时间与结直肠癌风险的联合关系。研究设计横断面研究。方法数据来源于NHANES和KNHANES。使用全球身体活动问卷评估PA和久坐时间。采用分层分析和限制三次样条的逻辑回归来评估相关性。还进行了种族亚组分析。结果在338例结直肠癌患者中(NHANES: n = 103,加权人群:1,282,253;KNHANES: n = 235,加权人群:190,811),久坐时间大于8小时/天(参考值0- 4小时/天)仅与不活动PA (600 MET-min/周)的结直肠癌风险相关(NHANES: OR = 3.37, 95% CI: 1.03-11.05; KNHANES: OR = 1.47, 95% CI: 0.82-3.46)。非活跃PA的黑人和亚洲人患结直肠癌的风险与久坐时间有关。在久坐8小时的参与者中,较高的PA水平(≥2000 MET-min/week)与两个数据集中CRC风险的显著降低相关(NHANES: 2000 - 3999 MET-min/week, OR = 0.13, 95% CI: 0.02-0.77;≥4000 MET-min/week, OR = 0.08, 95% CI: 0.01-0.75; KNHANES: 2000 - 3999 MET-min/week, OR = 0.36, 95% CI: 0.11-0.98;≥4000 MET-min/week, OR = 0.33, 95% CI: 0.04-2.39)。联合分析表明,PA活跃且久坐时间较短的个体与降低结直肠癌风险相关。结论:久坐时间与较高的结直肠癌风险相关,但仅适用于PA不活跃的个体(<;600 MET-min/周)。高水平的PA对每天久坐8小时的CRC风险有更大的益处。活跃PA和低久坐时间的结合与降低结直肠癌风险密切相关。
{"title":"Do the associations of sedentary time with colorectal cancer risk differ by physical activity level and vice versa? A cross-sectional study of two large population-based surveys","authors":"Yuansen Ma , Xiaomei Wu , Yu Sun , Mouqian Wu , Qihui Tian , Jiahui Tian , Duo Xu , Meixi Gong , Xuanbing Li , Yefu Liu , Bo Zhu","doi":"10.1016/j.puhe.2025.106115","DOIUrl":"10.1016/j.puhe.2025.106115","url":null,"abstract":"<div><h3>Objectives</h3><div>Prolonged sedentary behavior increases colorectal cancer (CRC) risk, while physical activity (PA) may reduce it. However, whether PA can mitigate the adverse effects of sedentary time remains unclear. This study examines whether PA modifies the association between sedentary time and CRC risk, and vice versa, and estimates the joint associations of PA and sedentary time with CRC risk using two surveys.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>Data were drawn from NHANES and KNHANES. PA and sedentary time were assessed using the Global Physical Activity Questionnaire. Logistic regression with stratified analyses and restricted cubic splines was used to assess associations. Racial subgroup analyses were also performed.</div></div><div><h3>Results</h3><div>Among 338 CRC cases (NHANES: n = 103, weighted population: 1,282,253; KNHANES: n = 235, weighted population: 190,811), sedentary time greater than 8 h/day (reference 0-<4 h/day) was associated with CRC risk only among those with inactive PA (<600 MET-min/week) (NHANES: OR = 3.37, 95 % CI: 1.03–11.05; KNHANES: OR = 1.47, 95 % CI: 0.82–3.46). Black and Asian individuals with inactive PA showed a higher CRC risk associated with higher sedentary time. Among participants with >8 h sedentary time, higher PA levels (≥2000 MET-min/week) were associated with significantly reduced CRC risk in both datasets (NHANES: 2000–3999 MET-min/week, OR = 0.13, 95 % CI: 0.02–0.77; ≥4000 MET-min/week, OR = 0.08, 95 % CI: 0.01–0.75; KNHANES: 2000–3999 MET-min/week, OR = 0.36, 95 % CI: 0.11–0.98; ≥4000 MET-min/week, OR = 0.33, 95 % CI: 0.04–2.39). Joint analyses showed that individuals with active PA and low sedentary time were associated with reduced CRC risk.</div></div><div><h3>Conclusions</h3><div>Sedentary time was associated with higher CRC risk but only in individuals with inactive PA (<600 MET-min/week). Higher levels of PA showed greater benefit for CRC risk in those with sedentary time >8 h/day. The combination of active PA and low sedentary time was strongly associated with reduced CRC risk.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106115"},"PeriodicalIF":3.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145885054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-29DOI: 10.1016/j.puhe.2025.106121
Xiang Li , Juntong Li , Sheng Ye , Hui Liu , Yue Yang , Xuelei Lu , Heyue Jin , Li Liu
Objectives
Adolescent mental health issues have become a growing public health concern. This study seeks to identify potential profiles of mental health among Chinese adolescents and to detect high-risk groups for the formulation of targeted intervention strategies based on associated health risk behaviors (HRBs).
Study design
A cross-sectional study.
Methods
This study was based on the Monitoring and Intervention Project for Common Diseases and Health Influencing Factors among Secondary School Students in Nanjing, involving 9,865 secondary school students as participants. Latent profile analysis (LPA) was employed to identify mental health (symptoms of depression, anxiety, and stress, as well as sleep quality); categorical variables were analyzed by the chi-square test or Fisher's exact test, whereas multinomial logistic regression was used to examine associations between HRBs and distinct mental health profiles.
Results
Three profiles of mental health were identified among the adolescents, including “Low-risk Mental Health” (68.03 %), “Moderate-risk Mental Health” (26.19 %), and “High-risk Mental Health” (5.78 %). Compared with the “Low-risk Mental Health” profile, the “Moderate-risk Mental Health” profile was associated with behaviors such as drinking, injury, school bullying, unhealthy diet, internet addiction, physical activity, and outdoor activity time; and the “High-risk Mental Health” profile was associated with smoking, drinking, injury, school bullying, unhealthy diet, internet addiction, and outdoor activity time.
Conclusions
Several HRBs are associated with mental health among Chinese adolescents. Healthcare professionals should target these HRBs and implement comprehensive measures to protect adolescent mental health.
{"title":"Mental health profiles and correlates among Chinese adolescents: A latent profile analysis","authors":"Xiang Li , Juntong Li , Sheng Ye , Hui Liu , Yue Yang , Xuelei Lu , Heyue Jin , Li Liu","doi":"10.1016/j.puhe.2025.106121","DOIUrl":"10.1016/j.puhe.2025.106121","url":null,"abstract":"<div><h3>Objectives</h3><div>Adolescent mental health issues have become a growing public health concern. This study seeks to identify potential profiles of mental health among Chinese adolescents and to detect high-risk groups for the formulation of targeted intervention strategies based on associated health risk behaviors (HRBs).</div></div><div><h3>Study design</h3><div>A cross-sectional study.</div></div><div><h3>Methods</h3><div>This study was based on the Monitoring and Intervention Project for Common Diseases and Health Influencing Factors among Secondary School Students in Nanjing, involving 9,865 secondary school students as participants. Latent profile analysis (LPA) was employed to identify mental health (symptoms of depression, anxiety, and stress, as well as sleep quality); categorical variables were analyzed by the chi-square test or Fisher's exact test, whereas multinomial logistic regression was used to examine associations between HRBs and distinct mental health profiles.</div></div><div><h3>Results</h3><div>Three profiles of mental health were identified among the adolescents, including “Low-risk Mental Health” (68.03 %), “Moderate-risk Mental Health” (26.19 %), and “High-risk Mental Health” (5.78 %). Compared with the “Low-risk Mental Health” profile, the “Moderate-risk Mental Health” profile was associated with behaviors such as drinking, injury, school bullying, unhealthy diet, internet addiction, physical activity, and outdoor activity time; and the “High-risk Mental Health” profile was associated with smoking, drinking, injury, school bullying, unhealthy diet, internet addiction, and outdoor activity time.</div></div><div><h3>Conclusions</h3><div>Several HRBs are associated with mental health among Chinese adolescents. Healthcare professionals should target these HRBs and implement comprehensive measures to protect adolescent mental health.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106121"},"PeriodicalIF":3.2,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-29DOI: 10.1016/j.puhe.2025.106116
S. Sana , T. Magnée , S. van Pelt , V. Premysl , P.J.E. Bindels , S. Denktaş , E.I.T. de Schepper , P.L. Kocken
Objectives
Stringent COVID-19 lockdown measures with limited access to GP practices raised concerns about the primary mental care access for patients from deprived neighbourhoods. This study investigated the number of mental health GP consultations among patients in deprived neighbourhoods before and during the COVID-19 pandemic.
Study design
Observational study from January 2018 to June 2022.
Methods
Medical records of 379,567 patients were analyzed. We applied segmented time-series Poisson regression analyses to compare monthly mental health consultations in the first lockdown phase (March–May 2020) and the period thereafter with the pre-pandemic period for the total sample and separately for patients in deprived and non-deprived neighbourhoods.
Results
Analysis of 759,863 mental health consultations showed fewer consultations during the first lockdown phase, than pre-pandemic levels (RR = 0·955; 95 % CI = 0·919–0·993). This decrease was only significant among patients in non-deprived neighbourhoods Conversely, a significant increase in consultations during the post-lockdown phase was observed among patients in deprived neighbourhoods (RR = 1·074; 95 % CI = 1·002–1·152), returning to pre-pandemic levels for patients in non-deprived neighbourhoods. For the whole study population, patients had more consultations per month during the first lockdown phase and post-lockdown phase (RR = 1·095; 95 % CI = 1·079–1·111 and RR = 1·064; 95 % CI = 1·051–1·078 respectively).
Conclusions
During the lockdown phase the GP seemed accessible for patients with mental health problems in deprived neighbourhoods. A general decline in consultations during first lockdown phase, only significant in non-deprived neighbourhoods, was followed by increase in deprived neighbourhoods only during post-lockdown. This can be explained by a higher frequency of mental health consultations per patient. Sufficient access to primary health care should be guaranteed to ensure mental health treatment.
目标:严格的COVID-19封锁措施以及对全科医生诊所的限制,引发了人们对贫困社区患者获得初级精神保健的担忧。本研究调查了在COVID-19大流行之前和期间贫困社区患者的心理健康全科医生咨询次数。研究设计:2018年1月至2022年6月的观察性研究。方法:对379,567例患者的病历资料进行分析。我们应用分段时间序列泊松回归分析,将第一个封锁阶段(2020年3月至5月)及其后的时期与大流行前时期的每月心理健康咨询进行比较,并分别对贫困和非贫困社区的患者进行比较。结果:对759,863份心理健康咨询的分析显示,在第一个封锁阶段,咨询人数少于大流行前(RR = 0.955; 95% CI = 0.919 - 0.993)。相反,在封锁后阶段,贫困社区患者的咨询人数显著增加(RR = 1.074; 95% CI = 1.002 - 1.152),非贫困社区患者的咨询人数恢复到大流行前的水平。在整个研究人群中,患者在封城第一阶段和封城后每月就诊次数较多(RR = 1.095; 95% CI = 1.079 - 1.0111; RR = 1.064; 95% CI = 1.051 - 1.078)。结论:在封锁阶段,家庭医生似乎可以为贫困社区的精神健康问题患者提供帮助。在第一个封锁阶段,咨询人数普遍下降,仅在非贫困社区显著下降,随后只有在封锁后,贫困社区的咨询人数才有所增加。这可以解释为每个病人接受心理健康咨询的频率较高。应保证充分获得初级卫生保健,以确保精神卫生治疗。
{"title":"Restricted access to GPs had limited effect on consultations for mental health problems in deprived areas during COVID-19: A cohort study","authors":"S. Sana , T. Magnée , S. van Pelt , V. Premysl , P.J.E. Bindels , S. Denktaş , E.I.T. de Schepper , P.L. Kocken","doi":"10.1016/j.puhe.2025.106116","DOIUrl":"10.1016/j.puhe.2025.106116","url":null,"abstract":"<div><h3>Objectives</h3><div>Stringent COVID-19 lockdown measures with limited access to GP practices raised concerns about the primary mental care access for patients from deprived neighbourhoods. This study investigated the number of mental health GP consultations among patients in deprived neighbourhoods before and during the COVID-19 pandemic.</div></div><div><h3>Study design</h3><div>Observational study from January 2018 to June 2022.</div></div><div><h3>Methods</h3><div>Medical records of 379,567 patients were analyzed. We applied segmented time-series Poisson regression analyses to compare monthly mental health consultations in the first lockdown phase (March–May 2020) and the period thereafter with the pre-pandemic period for the total sample and separately for patients in deprived and non-deprived neighbourhoods.</div></div><div><h3>Results</h3><div>Analysis of 759,863 mental health consultations showed fewer consultations during the first lockdown phase, than pre-pandemic levels (RR = 0·955; 95 % CI = 0·919–0·993). This decrease was only significant among patients in non-deprived neighbourhoods Conversely, a significant increase in consultations during the post-lockdown phase was observed among patients in deprived neighbourhoods (RR = 1·074; 95 % CI = 1·002–1·152), returning to pre-pandemic levels for patients in non-deprived neighbourhoods. For the whole study population, patients had more consultations per month during the first lockdown phase and post-lockdown phase (RR = 1·095; 95 % CI = 1·079–1·111 and RR = 1·064; 95 % CI = 1·051–1·078 respectively).</div></div><div><h3>Conclusions</h3><div>During the lockdown phase the GP seemed accessible for patients with mental health problems in deprived neighbourhoods. A general decline in consultations during first lockdown phase, only significant in non-deprived neighbourhoods, was followed by increase in deprived neighbourhoods only during post-lockdown. This can be explained by a higher frequency of mental health consultations per patient. Sufficient access to primary health care should be guaranteed to ensure mental health treatment.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106116"},"PeriodicalIF":3.2,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1016/j.puhe.2025.106111
Sarah Gray , Shuaijun Guo , Cindy Pham , Marnie Downes , Katherine Lange , Sue Woolfenden , Gerry Redmond , Naomi Priest , Meredith O'Connor , Hannah Badland , Francisco Azpitarte , Sharon Goldfeld
Objectives
Cross-sectoral linked administrative data provides a powerful tool for population-level evaluations of child disadvantage. We examined individual-and area-level indicators of disadvantage in early childhood in Australia and estimated their associations with children's developmental outcomes at school entry.
Study design
Cross-sectional study.
Methods
We drew on data from the Person Level Integrated Data Asset (PLIDA) involving children born in Australia from 01/01/2012 to 31/07/2013, who commenced full-time schooling in 2018 and participated in the Australian Early Development Census (AEDC) (N = 274,123). Individual-level disadvantage was measured using 22 early childhood indicators across four pre-determined social determinant lenses (sociodemographic, geographic, health conditions, and risk factors). Area-level disadvantage was assessed using the Socio-Economic Indexes for Areas (SEIFA), based on each child's residential address. Teacher-reported poor developmental outcomes were assessed at school entry (4–6 years) in the AEDC.
Results
The percentage of children exposed to different aspects of individual-level disadvantage ranged from 0.2 % (parental death) to 58.8 % (parental mental health issues). There was substantial variation in children's experiences of individual-level disadvantage by geography. The associations between individual-and area-level disadvantage and poor developmental outcomes varied, with the individual-level indicator ‘child not regularly read to at home’ having the strongest association (risk ratio = 4.06, 95 % CI: 4.00 to 4.11). A dose-response relationship was observed, with exposure to an increasing number of child disadvantage indicators associated with poorer developmental outcomes.
Conclusion
Addressing children's experiences of multidimensional disadvantage requires cross-sectoral strategies that combine universal and proportionately targeted supports responsive to both individual-and area-level needs.
{"title":"Epidemiology of child disadvantage and developmental vulnerability in Australia: Insights from linked administrative data","authors":"Sarah Gray , Shuaijun Guo , Cindy Pham , Marnie Downes , Katherine Lange , Sue Woolfenden , Gerry Redmond , Naomi Priest , Meredith O'Connor , Hannah Badland , Francisco Azpitarte , Sharon Goldfeld","doi":"10.1016/j.puhe.2025.106111","DOIUrl":"10.1016/j.puhe.2025.106111","url":null,"abstract":"<div><h3>Objectives</h3><div>Cross-sectoral linked administrative data provides a powerful tool for population-level evaluations of child disadvantage. We examined individual-and area-level indicators of disadvantage in early childhood in Australia and estimated their associations with children's developmental outcomes at school entry.</div></div><div><h3>Study design</h3><div>Cross-sectional study.</div></div><div><h3>Methods</h3><div>We drew on data from the Person Level Integrated Data Asset (PLIDA) involving children born in Australia from 01/01/2012 to 31/07/2013, who commenced full-time schooling in 2018 and participated in the Australian Early Development Census (AEDC) (N = 274,123). Individual-level disadvantage was measured using 22 early childhood indicators across four pre-determined social determinant lenses (sociodemographic, geographic, health conditions, and risk factors). Area-level disadvantage was assessed using the Socio-Economic Indexes for Areas (SEIFA), based on each child's residential address. Teacher-reported poor developmental outcomes were assessed at school entry (4–6 years) in the AEDC.</div></div><div><h3>Results</h3><div>The percentage of children exposed to different aspects of individual-level disadvantage ranged from 0.2 % (parental death) to 58.8 % (parental mental health issues). There was substantial variation in children's experiences of individual-level disadvantage by geography. The associations between individual-and area-level disadvantage and poor developmental outcomes varied, with the individual-level indicator ‘child not regularly read to at home’ having the strongest association (risk ratio = 4.06, 95 % CI: 4.00 to 4.11). A dose-response relationship was observed, with exposure to an increasing number of child disadvantage indicators associated with poorer developmental outcomes.</div></div><div><h3>Conclusion</h3><div>Addressing children's experiences of multidimensional disadvantage requires cross-sectoral strategies that combine universal and proportionately targeted supports responsive to both individual-and area-level needs.</div></div>","PeriodicalId":49651,"journal":{"name":"Public Health","volume":"251 ","pages":"Article 106111"},"PeriodicalIF":3.2,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145841366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}