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A decoupling method based on phase-shift calculation by encoding color fringe pattern 基于相移计算的彩色条纹编码解耦方法
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108658
Although the RGB channel requires fewer images for performing 3D measurement than the sinusoidal fringe phase-shift method, the coupling between the channels affect the measurement accuracy. Along these lines, a novel decoupling method was proposed, which was based on phase-shift calculation by encoding sinusoidal color fringe patterns. In our approach, every six sinusoidal fringes in the sinusoidal fringe phase-shift method are encoded into four sinusoidal color fringe patterns. These sinusoidal color fringes can replace six sinusoidal fringes without the effect of crosstalk. Compared with the traditional sinusoidal color fringe phase-shift method, a higher measurement accuracy was demonstrated. Moreover, there was no need for preprocessing and post-processing, and the calculation speed was faster.
虽然与正弦波条纹相移法相比,RGB 通道进行三维测量所需的图像更少,但通道之间的耦合会影响测量精度。因此,我们提出了一种新颖的去耦方法,该方法是通过编码正弦彩色条纹图案进行相移计算。在我们的方法中,正弦条纹相移法中的每六个正弦条纹被编码成四个正弦彩色条纹图案。这些正弦彩色条纹可以取代六个正弦条纹,而不会产生串扰。与传统的正弦彩色条纹相移法相比,该方法的测量精度更高。此外,无需预处理和后处理,计算速度也更快。
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引用次数: 0
A blood pressure measurement system using fiber optic-based Fabry-Perot interferometer 使用基于光纤的法布里-珀罗干涉仪的血压测量系统
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108667
In this work, the development of a blood pressure (BP) system based on a fiber optic Fabry-Perot interferometer (FFPI) has been investigated. The developed system is consisted of 2 main parts: FFPI structure, and sensing probe, respectively. An aluminum-coated mirror and latex thin film have been used as a reflector and elastic material of the sensing probe. Moreover, the peak detection and also fringe counting techniques have been applied to convert the number of fringes to blood pressure and heart rate values. In addition, a standard digital sphygmomanometer has been utilized as a reference instrument for comparing the performance of FFPI sensor. Eighty-six volunteers aged 21 - 50 years old have been chosen to collect the experimental data. However, the sensing probe has been placed on right side of the neck, and a standard digital sphygmomanometer on the upper left arm of the volunteers. The results indicated that the developed system has ability to measure systolic blood pressure (SBP), and diastolic blood pressure (DBP) in the range of 91 to 128 mmHg, and 62 to 85 mmHg, respectively. Moreover, the heart rate (HR) has also been exploited in the range of 48 to 102 beats/min. By comparing the experimental results with the reference instrument, it found that the average percentage error from the blood pressure measurements is 2.84 %. Furthermore, the developed sensor has a sensitivity of 56.88 nm/mmHg. This implies that the developed system has the efficiency to measure vital signs and blood pressure with cuffless, low-cost, and non-invasive.
在这项工作中,对基于光纤法布里-珀罗干涉仪(FFPI)的血压(BP)系统的开发进行了研究。开发的系统由两个主要部分组成:FFPI 结构和传感探头。感测探头的反射镜和弹性材料分别是镀铝镜和乳胶薄膜。此外,还采用了峰值检测和条纹计数技术,将条纹数转换为血压和心率值。此外,还使用标准数字血压计作为参照仪器,以比较 FFPI 传感器的性能。我们选择了 86 名年龄在 21-50 岁之间的志愿者来收集实验数据。不过,传感探头被放置在志愿者的颈部右侧,而标准数字血压计被放置在志愿者的左上臂。结果表明,所开发的系统能够测量收缩压(SBP)和舒张压(DBP),范围分别为 91 至 128 毫米汞柱和 62 至 85 毫米汞柱。此外,还测量了心率(HR),范围为 48 至 102 次/分钟。通过将实验结果与参考仪器进行比较,发现血压测量的平均百分比误差为 2.84%。此外,所开发传感器的灵敏度为 56.88 nm/mmHg。这意味着所开发的系统具有测量生命体征和血压的效率,且无需袖带、成本低廉、无创。
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引用次数: 0
Wavefront sensing and optical surface measurement method based on reference light modulation 基于参考光调制的波前传感和光学表面测量方法
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108659
This paper proposes a reflection-type surface coherent interferometric modulation imaging (R-CIMI) method based on reference light modulation, leveraging the interference light path generated by the reflected beam of the modulator and the target surface. Furthermore, we present a mask optimization strategy to enhance the similarity of diffraction pattern structures, as well as an automatic positioning approach based on optical field estimation. Owing to the anti-disturbance properties of coherent diffraction imaging, R-CIMI is less susceptible to environmental disturbances than conventional interference techniques. Simulations and experiments demonstrate that the proposed method is comparable to conventional interference methods in terms of measurement accuracy.
本文提出了一种基于参考光调制的反射型表面相干干涉调制成像(R-CIMI)方法,利用了调制器反射光束与目标表面产生的干涉光路。此外,我们还提出了增强衍射图样结构相似性的掩模优化策略,以及基于光场估计的自动定位方法。由于相干衍射成像的抗干扰特性,R-CIMI 比传统干扰技术更不易受环境干扰的影响。模拟和实验证明,所提出的方法在测量精度方面可与传统干涉方法相媲美。
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引用次数: 0
Tailoring freeform off-axis reflective beam shaping systems 定制自由形态离轴反射光束整形系统
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108665
Freeform optics have been extensively utilized in optical systems during the last few decades. Compared to their refractive counterparts, freeform reflective optics can yield larger angle of deflection, and more flexible geometry in three-dimensional space. Moreover, they are dispersion-free, and superior in thermal management. However, designing freeform reflective optics in highly tilted geometry is still not well addressed. In this paper, we propose a general formulation to design freeform off-axis reflective optics for precise illumination/intensity tailoring in highly tilted geometry. The superiority and effectiveness of the proposed method are verified by both numerical simulation and experimental results.
在过去的几十年里,自由曲面光学技术已被广泛应用于光学系统中。与折射光学器件相比,自由曲面反射光学器件的偏转角度更大,在三维空间中的几何形状更灵活。此外,它们不存在色散,在热管理方面也更胜一筹。然而,在高倾斜几何形状中设计自由曲面反射光学器件的问题仍然没有得到很好的解决。在本文中,我们提出了设计自由形态离轴反射光学器件的一般方法,以在高度倾斜的几何形状中实现精确的照明/强度定制。数值模拟和实验结果验证了所提方法的优越性和有效性。
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引用次数: 0
Measurement of lens parameters based on Shack-Hartmann wavefront sensor 基于夏克-哈特曼波前传感器的透镜参数测量
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108666
The focal length, radius of curvature, and refractive index are key parameters of a spherical lens. Here, an approach for measuring lens parameters based on the Shack-Hartmann wavefront sensor (SHS) is proposed. Firstly, the position of the reference point for measuring focal length is determined by the figure-of-merit function, called the least square sum of centroids shifts (LSSCS), from the spot array formed by the microlens array of SHS. The focal length is estimated by measuring radii of curvatures of two spherical waves. Each spherical wave is caused by the distance between the focal point of the lens and the determined reference. Secondly, the radius of curvature is the difference between two coordinate locations of the lens. Each location, corresponding to a collimated beam reflected from the lens, is determined by the figure-of-merit function LSSCS. Thirdly, the refractive index can be further estimated by lens maker's equation through the measured focal length and radius of curvature. A positive and a negative lens are both tested by the proposed method. Experimental results show that the lens parameters measured by the proposed method are in good agreement with the nominal values. The proposed method does not require wavefront reconstruction, and is simple, accurate and noise-resistant.
焦距、曲率半径和折射率是球面透镜的关键参数。本文提出了一种基于 Shack-Hartmann 波前传感器(SHS)的透镜参数测量方法。首先,测量焦距的参考点位置是由 SHS 微透镜阵列形成的光斑阵列的优点函数确定的,该函数被称为中心点移动的最小平方和(LSSCS)。焦距是通过测量两个球面波的曲率半径来估算的。每个球面波都是由透镜焦点与确定的参照物之间的距离引起的。其次,曲率半径是透镜两个坐标位置之间的差值。每个位置与透镜反射的准直光束相对应,由函数 LSSCS 确定。第三,通过测量焦距和曲率半径,可根据透镜制造商方程进一步估算折射率。利用所提出的方法测试了正透镜和负透镜。实验结果表明,用拟议方法测量的透镜参数与标称值非常吻合。所提出的方法无需波前重建,简单、准确且抗噪。
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引用次数: 0
Uncertainty-assisted virtual immunohistochemical detection on morphological staining via semi-supervised learning 通过半监督学习对形态染色进行不确定性辅助虚拟免疫组化检测
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108657
Tumor suppressor gene TP53 plays a crucial role in cancer diagnosis and prognosis. The gene encodes the tumor suppressor protein p53, which can be identified through immunohistochemical (IHC) staining in various cancers, including gastric carcinoma. However, IHC staining is more costly and therefore not as prevalent as routine hematoxylin-eosin (H&E) staining. In this study, we present a semi-supervised learning-based approach for immunological detection (SSID) of TP53 mutation directly on H&E-stained gastric tissue sections, intending to improve gastric cancer diagnosis. SSID is trained on a small set of annotated image pairs and a larger unannotated dataset of H&E-stained images. It can detect the regions showing strong p53 expression, indicating TP53 mutation, and we validate the accuracy of our approach through both qualitative assessment (pathologists' average score of 2.22/3) and quantitative evaluation (e.g., averaged mean Intersection-over-Union of 0.73). Moreover, we introduce Bayesian uncertainty to assess the credibility of the detected masks, aiming to prevent misdiagnosis and inappropriate treatment. Our results demonstrate that SSID can circumvent the expensive and laborious IHC staining procedures and enable the diagnosis and prognosis of gastric cancer through immunological detection of TP53 mutation.
抑癌基因 TP53 在癌症诊断和预后中起着至关重要的作用。该基因编码肿瘤抑制蛋白 p53,在包括胃癌在内的各种癌症中,可以通过免疫组化(IHC)染色来识别 p53。然而,IHC 染色成本较高,因此不如常规苏木精-伊红(H&E)染色普遍。在本研究中,我们提出了一种基于半监督学习的方法,可直接在 H&E 染色的胃组织切片上进行 TP53 突变的免疫检测(SSID),旨在改进胃癌诊断。SSID 是在一小部分有注释的图像对和更大的未注释 H&E 染色图像数据集上进行训练的。我们通过定性评估(病理学家的平均评分为 2.22/3)和定量评估(例如,平均交叉联合平均值为 0.73)验证了我们方法的准确性。此外,我们还引入了贝叶斯不确定性来评估检测到的掩码的可信度,旨在防止误诊和不当治疗。我们的研究结果表明,SSID 可以避开昂贵而费力的 IHC 染色过程,通过免疫学检测 TP53 突变来诊断胃癌并作出预后。
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引用次数: 0
Edge enhancement and feature modulation based network for light field depth estimation 基于边缘增强和特征调制的光场深度估算网络
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-30 DOI: 10.1016/j.optlaseng.2024.108662
Estimating depth from light field images is a critical issue in light field applications. While learning-based methods have made significant strides in light field depth estimation, achieving high accuracy and speed simultaneously remains a major challenge. This paper proposes a light field depth estimation network based on edge enhancement and feature modulation, which significantly improves depth estimation results by emphasizing inter-view correlations while preserving image edge features. Specifically, to prioritize edge details, we introduce an Edge-Enhanced Cost Constructor (EECC) that integrates edge information with existing cost constructors to improve depth estimation performance in complex areas. Furthermore, most light field depth estimation networks utilize only sub-aperture images (SAIs) without considering the inherent angular information in macro-pixel image (MacPI). To address this limitation, we propose the MacPI-Guided Feature Modulation (MGFM) module, which leverages angular information between different views in MacPI to modulate features at each view. Experimental results show that our method not only performs excellently on synthetic datasets but also demonstrates outstanding generalization on real-world datasets, achieving a better balance between accuracy and computation speed.
从光场图像中估计深度是光场应用中的一个关键问题。虽然基于学习的方法在光场深度估计方面取得了长足进步,但同时实现高精度和高速度仍是一大挑战。本文提出了一种基于边缘增强和特征调制的光场深度估算网络,在保留图像边缘特征的同时,强调视图间的相关性,从而显著改善深度估算结果。具体来说,为了优先考虑边缘细节,我们引入了边缘增强成本构造器(EECC),将边缘信息与现有的成本构造器整合在一起,以提高复杂区域的深度估计性能。此外,大多数光场深度估计网络只利用子孔径图像(SAI),而不考虑宏像素图像(MacPI)中固有的角度信息。为了解决这一局限性,我们提出了 MacPI 引导的特征调制(MGFM)模块,该模块利用 MacPI 中不同视图之间的角度信息来调制每个视图的特征。实验结果表明,我们的方法不仅在合成数据集上表现出色,而且在真实世界数据集上也表现出突出的通用性,在准确性和计算速度之间实现了更好的平衡。
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引用次数: 0
Parallel multiplexing optical spatial differentiation based on a superposed complex amplitude filter 基于叠加复振幅滤波器的并行复用光学空间分辨技术
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-29 DOI: 10.1016/j.optlaseng.2024.108669
Optical differentiation has the advantages of ultrahigh speed and low power consumption over digital electronic computing. Various methods for single and switchable-order differential operations have been extensively studied and applied in fields such as image processing and optical analog computing. Here, we report a parallel multiplexing scheme of optical spatial differentiations via a superposition of multiple complex amplitude filters. The isotropic and anisotropic first- to fourth-order differentiation multiplexing, as well as various types of differentiation multiplexing are demonstrated both theoretically and experimentally. Multifunctional differential operations can be generated simultaneously, realizing the extraction of multiple feature information about amplitude and phase objects. This proof-of-principle work provides an approach for multiplexing optical spatial differentiation and a promising possibility for efficient information processing.
与数字电子计算相比,光学微分具有超高速和低功耗的优点。各种单阶和可切换阶微分操作方法已被广泛研究并应用于图像处理和光学模拟计算等领域。在此,我们报告了一种通过多个复振幅滤波器的叠加实现光学空间微分的并行复用方案。我们从理论和实验两方面展示了各向同性和各向异性的一阶至四阶微分复用,以及各种类型的微分复用。多功能微分操作可同时产生,实现了对振幅和相位对象的多种特征信息提取。这项原理验证工作为光学空间微分多路复用提供了一种方法,也为高效信息处理提供了可能。
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引用次数: 0
3D geometric attenuation factor for discrete Gaussian microsurfaces 离散高斯微表面的三维几何衰减系数
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-29 DOI: 10.1016/j.optlaseng.2024.108656
The geometric attenuation factor plays an important role in the construction of polarized bidirectional reflection distribution function (pBRDF) model, but the traditional geometric attenuation factor theory neglects the influence of microsurface height on the shadowing and masking effects of light. Therefore, we present a geometric attenuation factor related to the height of the discrete Gaussian microsurface based on microfacet theory. We correspond each sampled point on the microsurface to an element in the attenuation matrix, and assign values to the elements of the attenuation matrix by determining whether the sampling points are illuminated or observable. Finally, we can get the numerical solution of the geometric attenuation factor of the 3D discrete Gaussian microsurface by calculating the attenuation matrix. The results show that the presented geometric attenuation factor is reasonable and effective, and can be better applied to pBRDF model to improve the accuracy of pBRDF model.
几何衰减系数在偏振双向反射分布函数(pBRDF)模型的构建中起着重要作用,但传统的几何衰减系数理论忽略了微表面高度对光的阴影和掩蔽效应的影响。因此,我们根据微面理论提出了与离散高斯微面高度相关的几何衰减系数。我们将微表面上的每个采样点与衰减矩阵中的一个元素对应起来,并通过确定采样点是否被照亮或可观测,为衰减矩阵的元素赋值。最后,我们可以通过计算衰减矩阵得到三维离散高斯微表面几何衰减系数的数值解。结果表明,所提出的几何衰减系数合理有效,可以更好地应用于 pBRDF 模型,提高 pBRDF 模型的精度。
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引用次数: 0
Selective manipulation of particles for multifunctional optical fiber tweezers with wavelength division multiplexing technology 利用波分复用技术实现多功能光纤镊子对颗粒的选择性操纵
IF 3.5 2区 工程技术 Q2 OPTICS Pub Date : 2024-10-29 DOI: 10.1016/j.optlaseng.2024.108661
We propose and demonstrate a multifunctional tapered optical fiber tweezers (MTOFT) for capturing and manipulating micro particles. By employing the wavelength division multiplexing technology, two wavelengths, 980 nm and 650 nm, are coupled into optical fiber tweezers to achieve the flexibility of capture, transport and release of particles with different refractive indexes using fabricated tapered optical fiber probe (TOFP). Wherein, the 980 nm light wave excites LP01 and LP11 modes beams, and the 650 nm light wave excites LP01, LP11, LP21 and LP02 modes beams. Simulations and experiments demonstrated that the capture of yeast and the ejection of silica are achieved with the laser beam at 980nm wavelength. At 650 nm laser beam, the capture of silica and the ejection of yeast are achieved. This structure enables flexible manipulation of different particles by combining multiple wavelengths, expanding the direction of combining particle transport and particle emission functions.
我们提出并演示了一种用于捕捉和操纵微粒的多功能锥形光纤镊子(MTOFT)。通过采用波分复用技术,将 980 nm 和 650 nm 两种波长耦合到光纤镊子中,利用制作的锥形光纤探针(TOFP)实现对不同折射率颗粒的灵活捕获、传输和释放。其中,980 nm 光波激发 LP01 和 LP11 模式光束,650 nm 光波激发 LP01、LP11、LP21 和 LP02 模式光束。模拟和实验证明,波长为 980nm 的激光束可实现酵母的捕获和二氧化硅的喷射。在波长为 650nm 的激光束下,实现了二氧化硅的捕获和酵母的喷射。这种结构可以通过组合多种波长灵活操纵不同的粒子,扩大了粒子传输和粒子发射功能的组合方向。
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引用次数: 0
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Optics and Lasers in Engineering
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