Pub Date : 2026-06-01Epub Date: 2026-02-03DOI: 10.1016/j.optlaseng.2026.109665
Aswathi K Sivarajan, Harsh Vardhan, Sakshi Choudhary, Salla Gangi Reddy, Ravi Kumar
Perfect Optical Vortex (POV) beams have gained significant attention due to their ability to maintain a constant ring size with increasing topological charge (TC). This property of the POV beam helps to attain a vortex beam with large TC and controllable ring size simultaneously. In this paper, we propose a new simple way to generate twin ring POV (TR-POV) beam by introducing a conical phase into the Bessel phase function. In TR-POV, we can precisely control the transverse cross-section profile, where the ring radius, ring width, and TC of both rings can be assigned arbitrarily, depending on the application. We have experimentally generated these beams and studied their detailed propagation characteristics in free space. Through the interferometric analysis, we have also determined the TCs correspond to both the rings. We believe that the proposed beams can have profound application in various optical domains, such as microscopy, imaging through turbid media, communication, security etc.
{"title":"Tunable twin-ring perfect optical vortex beams and their propagation characteristics","authors":"Aswathi K Sivarajan, Harsh Vardhan, Sakshi Choudhary, Salla Gangi Reddy, Ravi Kumar","doi":"10.1016/j.optlaseng.2026.109665","DOIUrl":"10.1016/j.optlaseng.2026.109665","url":null,"abstract":"<div><div>Perfect Optical Vortex (POV) beams have gained significant attention due to their ability to maintain a constant ring size with increasing topological charge (TC). This property of the POV beam helps to attain a vortex beam with large TC and controllable ring size simultaneously. In this paper, we propose a new simple way to generate twin ring POV (TR-POV) beam by introducing a conical phase into the Bessel phase function. In TR-POV, we can precisely control the transverse cross-section profile, where the ring radius, ring width, and TC of both rings can be assigned arbitrarily, depending on the application. We have experimentally generated these beams and studied their detailed propagation characteristics in free space. Through the interferometric analysis, we have also determined the TCs correspond to both the rings. We believe that the proposed beams can have profound application in various optical domains, such as microscopy, imaging through turbid media, communication, security etc.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109665"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-02-06DOI: 10.1016/j.optlaseng.2026.109675
Yurong Li , Yi Zhou , Shikai Wu , Zhen Li , Jinsheng Zhang , Zhongquan Wen , Zhihai Zhang , Jing Xiang , Zhengguo Shang , GaoFeng Liang , Yin She , Gang Chen
Phase-contrast optical microscopy technology converts phase variations in transparent specimens into visible intensity variations and has played a pivotal role in the advancement of modern biomedicine. However, most research on phase-contrast microscopes is predominantly based on the Zernike phase-contrast microscope configuration, which employs conventional optics for sample illumination. Therefore, their resolution is fundamentally limited. To further improves the resolution, we propose a super-resolution phase-contrast technique that integrates a super-oscillation illuminating metalens with a phase-plate in a confocal microscope configuration. Experiments demonstrated the proposed super-resolution phase-contrast can resolve a phase-type grating with a linewidth of 120 nm, a pitch of 240 nm, and a phase difference of 0.5π, demonstrating a novel super-resolution phase-contrast microscopy modality. Our method holds great potential in probing nanoscale structures in transparent samples, such as cells and biomedical tissues.
{"title":"Phase-contrast super-resolution microscopy based on super-oscillation illumination","authors":"Yurong Li , Yi Zhou , Shikai Wu , Zhen Li , Jinsheng Zhang , Zhongquan Wen , Zhihai Zhang , Jing Xiang , Zhengguo Shang , GaoFeng Liang , Yin She , Gang Chen","doi":"10.1016/j.optlaseng.2026.109675","DOIUrl":"10.1016/j.optlaseng.2026.109675","url":null,"abstract":"<div><div>Phase-contrast optical microscopy technology converts phase variations in transparent specimens into visible intensity variations and has played a pivotal role in the advancement of modern biomedicine. However, most research on phase-contrast microscopes is predominantly based on the Zernike phase-contrast microscope configuration, which employs conventional optics for sample illumination. Therefore, their resolution is fundamentally limited. To further improves the resolution, we propose a super-resolution phase-contrast technique that integrates a super-oscillation illuminating metalens with a phase-plate in a confocal microscope configuration. Experiments demonstrated the proposed super-resolution phase-contrast can resolve a phase-type grating with a linewidth of 120 nm, a pitch of 240 nm, and a phase difference of 0.5π, demonstrating a novel super-resolution phase-contrast microscopy modality. Our method holds great potential in probing nanoscale structures in transparent samples, such as cells and biomedical tissues.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109675"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-01-16DOI: 10.1016/j.optlaseng.2026.109604
Jianchao Guo , Mingguang Shan , Zhi Zhong , Bin Liu , Lei Yu , Lijing Wang , Lei Liu
The point diffraction interferometer (PDI) is a promising quantitative phase imaging (QPI) method, which has the advantages of compactness and stability. However, the field-of-view (FOV) of PDI is always compromised between the size of the sensor and the magnification. To solve this problem, a PDI with doubled FOV is set up by a grating placed outside the Fourier plane in a 4f system, which has a simple optical setup and larger FOV without decreasing the magnification. First, a 4f system is built up by two Lens. Then, a grating is placed outside the Fourier plane of the 4f system, while a hole array is placed exactly at the Fourier plane. The grating diffracts the object beam into several duplicates with relative offsets along its periodicity, each of which carries a different region of the object. The hole array comprises one pinhole and two large holes. One of ±1 diffraction orders is low-pass filtering by the pinhole to form the reference beam, while the other one of ±1 diffraction orders and 0th diffraction order pass through the large holes and act as the object beams with different FOV. The image sensor is placed at an overlapping area of two FOVs, which enables two distinct regions of the object to be captured simultaneously in a single shot. Moreover, induced by the different angles between the reference beam and the object beams, object beams with different FOVs have different spatial carrier frequencies in the multiplexed interferogram. To avoid crosstalk between the object beams, two object beams are modulated into orthogonal polarization states to avoid interference. The validity and feasibility of this PDI are verified by conducting experiments on a 1951USAF resolution plate, a bee wing, and onion epidermal cells. The experimental results show that this proposed PDI can double FOV without sacrificing image quality, which demonstrates various future applications in microscopic imaging and optical metrology.
{"title":"Doubled field-of-view of point diffraction interferometer with a grating outside the Fourier plane","authors":"Jianchao Guo , Mingguang Shan , Zhi Zhong , Bin Liu , Lei Yu , Lijing Wang , Lei Liu","doi":"10.1016/j.optlaseng.2026.109604","DOIUrl":"10.1016/j.optlaseng.2026.109604","url":null,"abstract":"<div><div>The point diffraction interferometer (PDI) is a promising quantitative phase imaging (QPI) method, which has the advantages of compactness and stability. However, the field-of-view (FOV) of PDI is always compromised between the size of the sensor and the magnification. To solve this problem, a PDI with doubled FOV is set up by a grating placed outside the Fourier plane in a 4<em>f</em> system, which has a simple optical setup and larger FOV without decreasing the magnification. First, a 4<em>f</em> system is built up by two Lens. Then, a grating is placed outside the Fourier plane of the 4<em>f</em> system, while a hole array is placed exactly at the Fourier plane. The grating diffracts the object beam into several duplicates with relative offsets along its periodicity, each of which carries a different region of the object. The hole array comprises one pinhole and two large holes. One of ±1 diffraction orders is low-pass filtering by the pinhole to form the reference beam, while the other one of ±1 diffraction orders and 0th diffraction order pass through the large holes and act as the object beams with different FOV. The image sensor is placed at an overlapping area of two FOVs, which enables two distinct regions of the object to be captured simultaneously in a single shot. Moreover, induced by the different angles between the reference beam and the object beams, object beams with different FOVs have different spatial carrier frequencies in the multiplexed interferogram. To avoid crosstalk between the object beams, two object beams are modulated into orthogonal polarization states to avoid interference. The validity and feasibility of this PDI are verified by conducting experiments on a 1951USAF resolution plate, a bee wing, and onion epidermal cells. The experimental results show that this proposed PDI can double FOV without sacrificing image quality, which demonstrates various future applications in microscopic imaging and optical metrology.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109604"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145981842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-01-19DOI: 10.1016/j.optlaseng.2026.109628
Junzhuo Zhou , Jun Zou , Ye Qiu , Zhihe Liu , Jia Hao , Wenli Li , Yiting Yu
Polarization imaging shows great potential for defect detection on highly reflective and low-contrast industrial surfaces. However, existing image fusion algorithms struggle to address the challenges of feature conflicts and polarization noise interference during the polarization fusion process. This paper proposes a polarization image fusion method based on analytical attention heads, aiming to integrate complementary information from different sources while enhancing the prominent features of the main source and suppressing polarization noise. The innovations of this paper are: 1) designing analytical attention heads based on mathematical principles to extract low-level image features such as gradients, textures, information, semantics, and noise; 2) detecting and enhancing prominent features in the main source image to solve the problem of feature loss caused by conflicting feature fusion from different sources; 3) detecting noisy regions in polarization image and reducing their fusion weights to avoid interference from polarization noise. We evaluated our method on both a self-built polarization image dataset and public datasets, and the results demonstrate the advanced nature of our approach. The source code and datasets are publicly available at: https://github.com/FiredTable/DeepFusion.
{"title":"Polarization image fusion via analytical attention heads: A multi-scale feature integration framework","authors":"Junzhuo Zhou , Jun Zou , Ye Qiu , Zhihe Liu , Jia Hao , Wenli Li , Yiting Yu","doi":"10.1016/j.optlaseng.2026.109628","DOIUrl":"10.1016/j.optlaseng.2026.109628","url":null,"abstract":"<div><div>Polarization imaging shows great potential for defect detection on highly reflective and low-contrast industrial surfaces. However, existing image fusion algorithms struggle to address the challenges of feature conflicts and polarization noise interference during the polarization fusion process. This paper proposes a polarization image fusion method based on analytical attention heads, aiming to integrate complementary information from different sources while enhancing the prominent features of the main source and suppressing polarization noise. The innovations of this paper are: 1) designing analytical attention heads based on mathematical principles to extract low-level image features such as gradients, textures, information, semantics, and noise; 2) detecting and enhancing prominent features in the main source image to solve the problem of feature loss caused by conflicting feature fusion from different sources; 3) detecting noisy regions in polarization image and reducing their fusion weights to avoid interference from polarization noise. We evaluated our method on both a self-built polarization image dataset and public datasets, and the results demonstrate the advanced nature of our approach. The source code and datasets are publicly available at: <span><span>https://github.com/FiredTable/DeepFusion</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109628"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Measuring the topological charge (TC) of optical vortices is crucial for advancing applications in areas such as optical communication and quantum information processing. Although various interferometric and non-interferometric techniques have been developed for coherent and partially coherent beams, most of these methods are ineffective for fractional-vortex beams, especially when the beam gets perturbed. In this work, we propose and experimentally demonstrate a simple, non-interferometric technique based on autocorrelation for assessing and quantitatively measuring the TC of fractional vortex beams. We generated fractional optical vortex beams using computer-generated fork-shaped holograms and then obtained the corresponding random optical patterns after scattering through a rough surface. The autocorrelation rings of random patterns provide the TC of fractional vortex beams, and the asymmetry gradually becomes symmetric as the TC approaches an integer value. Additionally, by examining the divergence of the first dark ring with respect to propagation distance, we can quantitatively estimate the fractional TC. The measured divergence closely matches theoretical results, achieving an accuracy of over 98 %. The proposed method eliminates the need for phase retrieval, coherence modulation, or interferometry, providing a practical and robust solution for measuring fractional TCs, even in the presence of perturbations such as scattering and mild atmospheric turbulence, which are common in free-space optical communication systems.
{"title":"Evolution of fractional vortices through intensity autocorrelation of scattered speckle patterns","authors":"MD. Haider Ansari , Velagala Ganesh , Sakshi Choudhary , Ravi Kumar , Shashi Prabhakar , Salla Gangi Reddy","doi":"10.1016/j.optlaseng.2026.109637","DOIUrl":"10.1016/j.optlaseng.2026.109637","url":null,"abstract":"<div><div>Measuring the topological charge (TC) of optical vortices is crucial for advancing applications in areas such as optical communication and quantum information processing. Although various interferometric and non-interferometric techniques have been developed for coherent and partially coherent beams, most of these methods are ineffective for fractional-vortex beams, especially when the beam gets perturbed. In this work, we propose and experimentally demonstrate a simple, non-interferometric technique based on autocorrelation for assessing and quantitatively measuring the TC of fractional vortex beams. We generated fractional optical vortex beams using computer-generated fork-shaped holograms and then obtained the corresponding random optical patterns after scattering through a rough surface. The autocorrelation rings of random patterns provide the TC of fractional vortex beams, and the asymmetry gradually becomes symmetric as the TC approaches an integer value. Additionally, by examining the divergence of the first dark ring with respect to propagation distance, we can quantitatively estimate the fractional TC. The measured divergence closely matches theoretical results, achieving an accuracy of over 98 %. The proposed method eliminates the need for phase retrieval, coherence modulation, or interferometry, providing a practical and robust solution for measuring fractional TCs, even in the presence of perturbations such as scattering and mild atmospheric turbulence, which are common in free-space optical communication systems.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109637"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-01-16DOI: 10.1016/j.optlaseng.2026.109620
Yingdong He , Wei Liu , Jiahe Ouyang , Jianhui Zhong , Chengbin Li , Yi Li , Yun Lin , Hao Dai , Zhijun Wu , Xining Zhang
A PDMS-encapsulated microfiber loop cavity (MLC) temperature sensor combined with a random forest (RF) model is proposed to achieve precise multipoint temperature prediction within millimeter-scale micro-regions. By constructing anisotropic thermal fields using orthogonal heating wires, the MLC’s optical responses were analyzed to infer temperatures at multiple discrete locations, including on- and off-microfiber positions. The RF model, trained with structural parameters and integrated optical intensity, achieved high prediction accuracy (RMSE≈2.5°C, R2≈0.97 for the horizontal heating) across multiple sensing points. Temperature gradients and their vector characteristics were subsequently derived from the predicted temperatures, revealing distinct spatial characteristics under horizontal and vertical heating that are strongly correlated with device geometry. This study demonstrates that integrating optical microcavity sensing with machine learning enables stable thermal analysis without requiring multi-sensor arrays, offering a promising route for microelectronic thermal management, structural health monitoring, and high-temperature warning in micro-nano devices.
{"title":"Machine-learning-enabled loop microcavity for multipoint sensing of microscale nonlinear thermal fields","authors":"Yingdong He , Wei Liu , Jiahe Ouyang , Jianhui Zhong , Chengbin Li , Yi Li , Yun Lin , Hao Dai , Zhijun Wu , Xining Zhang","doi":"10.1016/j.optlaseng.2026.109620","DOIUrl":"10.1016/j.optlaseng.2026.109620","url":null,"abstract":"<div><div>A PDMS-encapsulated microfiber loop cavity (MLC) temperature sensor combined with a random forest (RF) model is proposed to achieve precise multipoint temperature prediction within millimeter-scale micro-regions. By constructing anisotropic thermal fields using orthogonal heating wires, the MLC’s optical responses were analyzed to infer temperatures at multiple discrete locations, including on- and off-microfiber positions. The RF model, trained with structural parameters and integrated optical intensity, achieved high prediction accuracy (RMSE≈2.5°C, R<sup>2</sup>≈0.97 for the horizontal heating) across multiple sensing points. Temperature gradients and their vector characteristics were subsequently derived from the predicted temperatures, revealing distinct spatial characteristics under horizontal and vertical heating that are strongly correlated with device geometry. This study demonstrates that integrating optical microcavity sensing with machine learning enables stable thermal analysis without requiring multi-sensor arrays, offering a promising route for microelectronic thermal management, structural health monitoring, and high-temperature warning in micro-nano devices.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109620"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145969393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-02-11DOI: 10.1016/j.optlaseng.2026.109679
Conghao Wang , Huilan Liu , Biao Yan , Yijing Zhang , Yanhui Hu , Yuqian Gao , Li Huang , Qiang Fu , Qiangxian Qi , Zhe Zhao , Junjie Wang , Huikai Xie , Aimin Wang , Lishuang Feng , Dawei Li
Two-photon endomicroscopy (2PEM) is an advanced optical biopsy technique that provides high-resolution, label-free, depth-resolved imaging. Developing a 2PEM with low driving voltage is essential for clinical applicability. This study presents a raster-scanning 2PEM that employs an ultra-compact, low-voltage electrothermal microelectromechanical system (MEMS) scanning mirror. The probe features separate designs for excitation and collection optical paths, integrating an electrothermal MEMS scanner for high-uniformity raster scanning. The system achieves an imaging resolution of ∼1.69 μm, a field of view of 103 μm × 103 μm at driving voltages below 4 V, and a frame rate of ∼0.5 frames per second (256 × 256 pixels). Imaging results of unstained skin tissue sections and ex vivo mouse rectum tissues demonstrate the system’s capability for label-free two-photon fluorescence and second-harmonic generation endomicroscopic imaging.
{"title":"Raster-scanning two-photon endomicroscopy with ultra-compact, low-voltage electrothermal MEMS scanning mirror","authors":"Conghao Wang , Huilan Liu , Biao Yan , Yijing Zhang , Yanhui Hu , Yuqian Gao , Li Huang , Qiang Fu , Qiangxian Qi , Zhe Zhao , Junjie Wang , Huikai Xie , Aimin Wang , Lishuang Feng , Dawei Li","doi":"10.1016/j.optlaseng.2026.109679","DOIUrl":"10.1016/j.optlaseng.2026.109679","url":null,"abstract":"<div><div>Two-photon endomicroscopy (2PEM) is an advanced optical biopsy technique that provides high-resolution, label-free, depth-resolved imaging. Developing a 2PEM with low driving voltage is essential for clinical applicability. This study presents a raster-scanning 2PEM that employs an ultra-compact, low-voltage electrothermal microelectromechanical system (MEMS) scanning mirror. The probe features separate designs for excitation and collection optical paths, integrating an electrothermal MEMS scanner for high-uniformity raster scanning. The system achieves an imaging resolution of ∼1.69 μm, a field of view of 103 μm × 103 μm at driving voltages below 4 V, and a frame rate of ∼0.5 frames per second (256 × 256 pixels). Imaging results of unstained skin tissue sections and ex vivo mouse rectum tissues demonstrate the system’s capability for label-free two-photon fluorescence and second-harmonic generation endomicroscopic imaging.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109679"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-02-11DOI: 10.1016/j.optlaseng.2026.109677
Anton E. Efimov , Daria O. Solovyeva , Oksana I. Sutyagina , Alexei V. Lyundup , Olga I. Agapova , Igor I. Agapov , Vladimir A. Oleinikov , Alexander V. Popov , Konstantin E. Mochalov
Advances in three-dimensional fluorescence microscopy are limited by poor axial resolution. We introduce Fluorescence Optical Nanotomography (FONT) system that bypasses this limitation by integrating widefield fluorescence imaging with serial ultramicrotomy. FONT achieves an axial resolution directly defined by the physical section thickness (40-200 nm), effectively decoupling it from optical diffraction. We demonstrate FONT's capability by reconstructing the 3D architecture of hepatocytes in rat liver and astrocytic networks in a mouse model of Alzheimer's disease, achieving a axial resolution of ∼100 nm/pixel. Furthermore, we present the design and theoretical validation of a dedicated platform that enables seamless correlation of FONT with in situ Scanning Probe Microscopy (SPM). This SPM-FONT platform is engineered to perform both modalities within a single cutting cycle, directly on the block-face, eliminating morphological artifacts. Our results establish FONT as a powerful standalone technique for nanoscale bioimaging and pave the way for a fully integrated correlative system to provide simultaneous topological, mechanical, and biochemical information from the same biological volume.
{"title":"In situ fluorescence optical nanotomography with ultra-high axial resolution","authors":"Anton E. Efimov , Daria O. Solovyeva , Oksana I. Sutyagina , Alexei V. Lyundup , Olga I. Agapova , Igor I. Agapov , Vladimir A. Oleinikov , Alexander V. Popov , Konstantin E. Mochalov","doi":"10.1016/j.optlaseng.2026.109677","DOIUrl":"10.1016/j.optlaseng.2026.109677","url":null,"abstract":"<div><div>Advances in three-dimensional fluorescence microscopy are limited by poor axial resolution. We introduce Fluorescence Optical Nanotomography (FONT) system that bypasses this limitation by integrating widefield fluorescence imaging with serial ultramicrotomy. FONT achieves an axial resolution directly defined by the physical section thickness (40-200 nm), effectively decoupling it from optical diffraction. We demonstrate FONT's capability by reconstructing the 3D architecture of hepatocytes in rat liver and astrocytic networks in a mouse model of Alzheimer's disease, achieving a axial resolution of ∼100 nm/pixel. Furthermore, we present the design and theoretical validation of a dedicated platform that enables seamless correlation of FONT with in situ Scanning Probe Microscopy (SPM). This SPM-FONT platform is engineered to perform both modalities within a single cutting cycle, directly on the block-face, eliminating morphological artifacts. Our results establish FONT as a powerful standalone technique for nanoscale bioimaging and pave the way for a fully integrated correlative system to provide simultaneous topological, mechanical, and biochemical information from the same biological volume.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109677"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-02-06DOI: 10.1016/j.optlaseng.2026.109676
Guanghui Jing , Tingting Wu , Jian Wen , Pengju Cao , Wei Liu , Yulin Wang , Mengying Lu , Su Sheng , Chao Jiang
In fiber-optic sensing technology, the escalating demand for high-sensitivity detection of ultraviolet (UV) and blue light has emerged as a critical driver. To address this urgent need, this paper proposes a fiber-optic sensing structure based on MZI principle. The sensor adopts a fundamental SMF-FMF-SMF configuration fabricated via fiber fusion splicing technology. A tapering process is applied to the FMF segment to optimize its sensing performance. For further enhancement of the interferometer’s sensing sensitivity, inorganic perovskite CsPbBr3 is selected as the sensitive material and uniformly deposited on the surface of the tapered FMF segment using the dip-coating method. Experimental results show that the detection sensitivities of the sensor for ultraviolet light and blue light reach 284.41 pm/(mW·cm⁻²) and 75.84 pm/(mW·cm⁻²), respectively. In addition, the sensor exhibits prominent advantages such as excellent stability, anti-electromagnetic interference capability, compact structure, and simple preparation process. It is expected to be a highly competitive candidate in the field of dual-band detection for ultraviolet and blue light.
{"title":"All-inorganic perovskite CsPbBr₃-assisted Mach-Zehnder Interferometer (MZI) optical fiber sensor for highly sensitive ultraviolet and blue light detection","authors":"Guanghui Jing , Tingting Wu , Jian Wen , Pengju Cao , Wei Liu , Yulin Wang , Mengying Lu , Su Sheng , Chao Jiang","doi":"10.1016/j.optlaseng.2026.109676","DOIUrl":"10.1016/j.optlaseng.2026.109676","url":null,"abstract":"<div><div>In fiber-optic sensing technology, the escalating demand for high-sensitivity detection of ultraviolet (UV) and blue light has emerged as a critical driver. To address this urgent need, this paper proposes a fiber-optic sensing structure based on MZI principle. The sensor adopts a fundamental SMF-FMF-SMF configuration fabricated via fiber fusion splicing technology. A tapering process is applied to the FMF segment to optimize its sensing performance. For further enhancement of the interferometer’s sensing sensitivity, inorganic perovskite CsPbBr<sub>3</sub> is selected as the sensitive material and uniformly deposited on the surface of the tapered FMF segment using the dip-coating method. Experimental results show that the detection sensitivities of the sensor for ultraviolet light and blue light reach 284.41 pm/(mW·cm⁻²) and 75.84 pm/(mW·cm⁻²), respectively. In addition, the sensor exhibits prominent advantages such as excellent stability, anti-electromagnetic interference capability, compact structure, and simple preparation process. It is expected to be a highly competitive candidate in the field of dual-band detection for ultraviolet and blue light.</div></div>","PeriodicalId":49719,"journal":{"name":"Optics and Lasers in Engineering","volume":"201 ","pages":"Article 109676"},"PeriodicalIF":3.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-06-01Epub Date: 2026-02-02DOI: 10.1016/j.optlaseng.2026.109670
Yujun Ma , Xueshi Zhang , Yesheng Wang , Fusheng Li , Qiuyi Han , Shanduan Zhang
Laser-generated plasma (LGP) light sources are critical for high-resolution bright field inspection of modern semiconductor wafer defects. This paper presents a 12 kW LGP system to enhance plasma radiance, employing reflective focusing with a low F-number to suppress plasma elongation. All optics are housed in a sealed chamber for operational safety. A novel alignment method is introduced to achieve precise optical alignment within the sealed chamber. This method uses a metal sphere to regularize the spot image and calculates component offset through image processing. The principle is analytically derived and verified via ray-tracing simulations, achieving a theoretical alignment accuracy of 0.01 mm. Experimental results demonstrate the robustness of the method: realignment consistently converged within 30 iterations across multiple disassembly-reassembly cycles. Moreover, a quantitative study reveals a clear decrease in output power as the offset of the optical axis increases. At a pump laser power of 6.0 kW, the system achieved an average output power of 315.8 W, with <0.4% variation over repeated cycles. This work provides a reliable, operator-independent alignment solution to ensure optimal performance of high-power LGP light sources.
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