Nutrition Metabolism and Cardiovascular Diseases最新文献

英文中文

Response to Letter to the Editor: Associations of disordered eating with the intestinal microbiota and short-chain fatty acids among young adults with type 1 diabetes 回应致编辑的信：1型糖尿病年轻成人中饮食紊乱与肠道微生物群和短链脂肪酸的关系

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-30 DOI: 10.1016/j.numecd.2024.08.017

Daria Igudesman

引用次数: 0

The serum uric acid to serum creatinine ratio is an independent risk factor for type 2 diabetes in community-dwelling elderly: A longitudinal analysis 血清尿酸与血清肌酐的比值是社区老年人罹患 2 型糖尿病的独立风险因素：纵向分析

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-30 DOI: 10.1016/j.numecd.2024.08.018

Qianqian Wang , Zhaoxiang Wang , Yuyan Sun , Fengyan Tang , Bing Lu , Kaixin Zhou , Ying Pan , Shao Zhong

Background and aim

Elevated serum uric acid (SUA) levels are an important marker of metabolic disorders. However, SUA levels largely depend on renal clearance function. This study aims to investigate the relationship between renal function-normalized SUA [SUA to serum creatinine (SCr) ratio] and the risk of developing type 2 diabetes in a community-dwelling elderly population.

Methods and results

A retrospective cohort study was conducted on elderly, non-diabetic individuals from the Kunshan community in China, who participated in annual health check-ups between January 2018 and December 2023. The relationship between the baseline SUA/SCr ratio and the risk of type 2 diabetes was examined using Cox regression models, restricted cubic splines (RCS), and subgroup analyses. After a median follow-up of 3.88 years, 778 cases of type 2 diabetes were identified among 7671 elderly non-diabetic individuals. Adjusting for confounding variables, the baseline SUA/SCr ratio was significantly linked to type 2 diabetes risk (P < 0.001). Individuals in the highest SUA/SCr ratio quartile had a 1.323 times higher risk of developing type 2 diabetes compared to those in the lowest quartile (HR = 1.323, 95% CI 1.053–1.661, P = 0.016). RCS analysis further confirmed this positive association. Additionally, subgroup analyses suggested that this relationship was particularly pronounced in female individuals.

Conclusions

In Chinese elderly community residents, the baseline SUA/SCr ratio is linked to the risk of type 2 diabetes. Monitoring this ratio could aid in predicting and assessing the risk of type 2 diabetes.

血清尿酸（SUA）水平升高是代谢紊乱的一个重要标志。然而，SUA 水平在很大程度上取决于肾脏清除功能。本研究旨在调查社区老年人群中肾功能正常化 SUA [SUA 与血清肌酐 (SCr) 比值] 与 2 型糖尿病发病风险之间的关系。我们对中国昆山社区的非糖尿病老年人进行了一项回顾性队列研究，这些人在2018年1月至2023年12月期间参加了年度健康体检。研究采用 Cox 回归模型、限制性立方样条（RCS）和亚组分析，考察了基线 SUA/SCr 比值与 2 型糖尿病风险之间的关系。经过中位 3.88 年的随访，在 7671 名非糖尿病老人中发现了 778 例 2 型糖尿病病例。对混杂变量进行调整后，基线 SUA/SCr 比值与 2 型糖尿病风险有显著联系（< 0.001）。与最低四分位数的人相比，SUA/SCr比率最高四分位数的人患2型糖尿病的风险高出1.323倍（HR = 1.323, 95% CI 1.053-1.661, = 0.016）。RCS 分析进一步证实了这种正相关性。此外，亚组分析表明，这种关系在女性中尤为明显。在中国老年社区居民中，基线 SUA/SCr 比值与罹患 2 型糖尿病的风险有关。监测这一比率有助于预测和评估罹患 2 型糖尿病的风险。

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引用次数: 0

Comment on: Association between liver fibrosis and stroke recurrence in young patients with ischemic stroke 评论年轻缺血性中风患者肝纤维化与中风复发之间的关系

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-29 DOI: 10.1016/j.numecd.2024.07.024

Aleeza Khowaja, Mahima Khatri, Satesh Kumar

引用次数: 0

Evaluating the impact of shift work on the risk of cardiometabolic disease: A Mendelian randomization study 评估轮班工作对心脏代谢疾病风险的影响：孟德尔随机研究

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-29 DOI: 10.1016/j.numecd.2024.08.010

Ye Cao , Yi Feng , Nan Xia , Jian-Cheng Zhang

Background and aims

Evidence is increasingly suggesting that shift work is a risk factor for cardiometabolic disease. However, the causal relationship between shift work and cardiometabolic disease is not yet fully understood. In this study, we employed two-sample Mendelian randomization (MR) to investigate the causal relationship between shift work and the risk of cardiometabolic outcomes.

Methods and results

Genome-wide association study (GWAS) statistics for shift work were obtained from the UK Biobank. Mendelian randomization analyses were conducted to explore the causal effects of shift work on cardiometabolic outcomes, using single-nucleotide polymorphisms (SNPs) as instrumental variables. The results suggested a causal effect between shift work and body mass index, body fat percentage, triglycerides, high-density lipoprotein, type 2 diabetes, hypertension, and cardiorespiratory fitness. After correcting for multiple tests, only body mass index and high-density lipoprotein showed significant associations. No causal effects were found between shift work and overweight, obesity, total cholesterol, low-density lipoprotein, fasting glucose, 2-h glucose, fasting insulin, coronary artery disease, myocardial infarction, heart failure, atrial fibrillation, or ischemic stroke.

Conclusion

This MR study provides genetic evidence for a suggestive causal link between shift work and certain cardiometabolic outcomes. Our research may have the significance of providing insight into public hygiene to improve the understanding of shift work and cardiometabolic disease risk. Further experimental studies are needed to confirm our findings.

越来越多的证据表明，轮班工作是心血管代谢疾病的一个风险因素。然而，轮班工作与心脏代谢疾病之间的因果关系尚未完全明了。在本研究中，我们采用了双样本孟德尔随机法（MR）来研究轮班工作与心脏代谢疾病风险之间的因果关系。轮班工作的全基因组关联研究（GWAS）统计数据来自英国生物库。利用单核苷酸多态性（SNPs）作为工具变量，进行了孟德尔随机分析，以探讨轮班工作对心脏代谢结果的因果效应。结果表明，轮班工作与体重指数、体脂百分比、甘油三酯、高密度脂蛋白、2 型糖尿病、高血压和心肺功能之间存在因果效应。经多重检验校正后，只有体重指数和高密度脂蛋白显示出显著的相关性。没有发现轮班工作与超重、肥胖、总胆固醇、低密度脂蛋白、空腹血糖、2 小时血糖、空腹胰岛素、冠心病、心肌梗塞、心力衰竭、心房颤动或缺血性中风之间存在因果关系。这项磁共振研究为轮班工作与某些心脏代谢结果之间的暗示性因果关系提供了遗传学证据。我们的研究可能具有公共卫生方面的意义，可以提高人们对轮班工作和心脏代谢疾病风险的认识。还需要进一步的实验研究来证实我们的发现。

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引用次数: 0

Virgin coconut oil mitigates ageing-associated oxidative stress and dyslipidaemia in male Wistar rats 初榨椰子油减轻雄性 Wistar 大鼠与衰老相关的氧化应激和血脂异常症状

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-27 DOI: 10.1016/j.numecd.2024.08.012

Sruthi Panniyan Kandiyil , Anit Jose , Chanjana Mohanan , Soorya Parathodi Illam , Achuthan C. Raghavamenon

Background and aim

Ageing often leads to the deterioration of physiological functions, including a decline in antioxidant defences, which can result in various health complications. Exogenous antioxidants have been recognised for their potential to alleviate these age-related health complications. Virgin coconut oil (VCO), known for its antioxidant, anti-inflammatory and anti-lipidemic efficacies, has gained recognition as a functional food with promising benefits. However, the safety of VCO consumption among individuals of the aged and diseased population remains to be fully established.

Methods and results

Five experimental groups were established, consisting of one control group and four groups administered either “2 mL” or “4 mL” per kg body weight of “HP-VCO” or “F-VCO” daily for six weeks. Body weight, water, and feed intake were monitored. After six weeks, animals were euthanized, blood and organs were collected for analysis. Oxidative stress and dyslipidemia markers were analysed, and liver tissues underwent histological examination.

HP-VCO-administered animals exhibited increased serum total cholesterol and triglycerides, whereas F-VCO-fed animals showed reduced triglyceride levels. LDL-cholesterol levels decreased in all VCO-fed groups, accompanied by increased HDL-cholesterol levels. Additionally, all treated groups showed a slight increase in the HMG Co. A/mevalonate ratio. Both VCO-fed animals displayed elevated reduced glutathione levels and reduced glutathione – S transferase activity. Consistent with these findings, decreased conjugated dienes and thiobarbituric acid reactive substances confirmed the improved redox status.

Conclusion

The study indicated that F-VCO is advantageous over VCO prepared by hot pressing as it offers protection against oxidative stress and related degenerative diseases.

衰老往往会导致生理机能退化，包括抗氧化防御能力下降，从而引发各种健康并发症。外源性抗氧化剂被认为具有缓解这些与年龄有关的健康并发症的潜力。初榨椰子油（VCO）以其抗氧化、抗炎和降血脂功效而闻名，已被公认为一种具有良好功效的功能性食品。然而，老年人和患病人群食用 VCO 的安全性仍有待全面证实。本研究设立了五个实验组，其中包括一个对照组和四个试验组，每公斤体重每天服用 "HP-VCO "或 "F-VCO""2 mL "或 "4 mL"，为期六周。对体重、水和饲料摄入量进行监测。六周后，动物被安乐死，并采集血液和器官进行分析。分析氧化应激和血脂异常指标，并对肝组织进行组织学检查。摄入 HP-VCO 的动物血清总胆固醇和甘油三酯水平升高，而摄入 F-VCO 的动物甘油三酯水平降低。所有喂食 VCO 的动物组的低密度脂蛋白胆固醇水平都有所下降，同时高密度脂蛋白胆固醇水平也有所上升。此外，所有治疗组的 HMG Co.A/mevalonate 比率略有上升。饲喂 VCO 的动物均显示还原型谷胱甘肽水平升高，谷胱甘肽 - S 转移酶活性降低。与这些发现一致的是，共轭二烯和硫代巴比妥酸活性物质的减少证实了氧化还原状态的改善。研究结果表明，与热加工制备的 VCO 相比，F-VCO 更具优势，因为它能防止氧化应激和相关的退行性疾病。

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引用次数: 0

Reply to comment on: Association between liver fibrosis and stroke recurrence in young patients with ischemic stroke by Aleeza Khowaja et al. 对 Aleeza Khowaja 等人的答复

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-26 DOI: 10.1016/j.numecd.2024.08.014

Xinyi Zhu , Jie Gao , Kang Yuan, Jinpeng Sun, Minmin Ma

引用次数: 0

Effect of cinnamon supplementation on blood pressure, oxidative stress, and inflammatory biomarkers in adults: An umbrella review of the meta-analyses of randomized controlled trials 补充肉桂对成人血压、氧化应激和炎症生物标志物的影响：随机对照试验荟萃分析综述

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-24 DOI: 10.1016/j.numecd.2024.08.009

Kaitian Zhang , Yang Li , Xuefeng Lin , Mazar Daneshar , Fatemeh Karamian , Mingzhu Li

Aims

Cinnamon has positive effects on markers of cardiometabolic health, including blood pressure (BP), oxidative stress, and inflammation. Despite the evidence accumulated from meta-analysis studies on the effects of cinnamon on these markers, the reported findings are still controversial. This umbrella review was conducted to evaluate the evidence and provide a definitive clarification.

Data synthesis

We conducted a systematic search in four scientific databases, including PubMed, Scopus, Web of Science, and Embase electronic databases, up to March 2024 to identify systematic reviews and meta-analyses of randomized clinical trials investigating the impact of cinnamon on blood pressure, oxidative stress, and inflammation. The findings revealed that cinnamon might exert favorable effects on systolic blood pressure (SBP) (ES = −2.36 mmHg; 95% CI: 3.86, −1.40), diastolic blood pressure (DBP) (ES = −1.65 mmHg; 95% CI: 2.41, −0.90), total antioxidant capacity (TAC) (WMD = 0.34; 95% CI: 0.04, 0.64), and interleukin-6 (IL-6) (WMD = −1.48; 95% CI: 2.96, −0.01). However, the results did not show any significant effect of cinnamon on malondialdehyde (MDA) (WMD = −0.47; 95% CI: 0.99, 0.05), C-reactive protein (CRP) (WMD = −1.33; 95% CI: 2.66, 0.00), and intercellular adhesion molecule 1 (ICAM-1) (WMD= 1.53, 95% CI: 12.03, 15.10).

Conclusions

The results of the studies included in this umbrella review support the usefulness of cinnamon consumption in modulating BP as well as improving TAC and IL-6 in metabolic disorders. Due to the limited number of studies, clinical diversity, and other limitations, more high-quality studies must be conducted to provide more precise and comprehensive recommendations.

Registration number

PROSPERO, CRD42023487350.

肉桂对包括血压（BP）、氧化应激和炎症在内的心脏代谢健康指标有积极影响。尽管有关肉桂对这些指标影响的荟萃分析研究积累了大量证据，但报告的结果仍存在争议。本综述旨在对证据进行评估并提供明确的解释。我们对截至 2024 年 3 月的四个科学数据库（包括 PubMed、Scopus、Web of Science 和 Embase 电子数据库）进行了系统检索，以确定研究肉桂对血压、氧化应激和炎症影响的随机临床试验的系统综述和荟萃分析。研究结果显示，肉桂可能对收缩压（SBP）（ES = -2.36 mmHg; 95% CI: 3.86, -1.40）、舒张压（DBP）（ES = -1.65 mmHg; 95% CI: 2.41, -0.90）、总抗氧化能力（TAC）（WMD = 0.34; 95% CI: 0.04, 0.64）和白细胞介素-6（IL-6）（WMD = -1.48; 95% CI: 2.96, -0.01）。然而，结果并未显示肉桂对丙二醛（MDA）（WMD = -0.47；95% CI：0.99，0.05）、C 反应蛋白（CRP）（WMD =-1.33；95% CI：2.66，0.00）和细胞间粘附分子 1（ICAM-1）（WMD：1.53，95% CI：12.03，15.10）有任何显著影响。纳入本综述的研究结果表明，食用肉桂有助于调节血压以及改善代谢紊乱患者的 TAC 和 IL-6。由于研究数量有限、临床多样性和其他局限性，必须开展更多高质量的研究，以提供更准确、更全面的建议。prospero，CRD42023487350。

{"title":"Effect of cinnamon supplementation on blood pressure, oxidative stress, and inflammatory biomarkers in adults: An umbrella review of the meta-analyses of randomized controlled trials","authors":"Kaitian Zhang , Yang Li , Xuefeng Lin , Mazar Daneshar , Fatemeh Karamian , Mingzhu Li","doi":"10.1016/j.numecd.2024.08.009","DOIUrl":"10.1016/j.numecd.2024.08.009","url":null,"abstract":"<div><h3>Aims</h3><div>Cinnamon has positive effects on markers of cardiometabolic health, including blood pressure (BP), oxidative stress, and inflammation. Despite the evidence accumulated from meta-analysis studies on the effects of cinnamon on these markers, the reported findings are still controversial. This umbrella review was conducted to evaluate the evidence and provide a definitive clarification.</div></div><div><h3>Data synthesis</h3><div>We conducted a systematic search in four scientific databases, including PubMed, Scopus, Web of Science, and Embase electronic databases, up to March 2024 to identify systematic reviews and meta-analyses of randomized clinical trials investigating the impact of cinnamon on blood pressure, oxidative stress, and inflammation. The findings revealed that cinnamon might exert favorable effects on systolic blood pressure (SBP) (ES = −2.36 mmHg; 95% CI: 3.86, −1.40), diastolic blood pressure (DBP) (ES = −1.65 mmHg; 95% CI: 2.41, −0.90), total antioxidant capacity (TAC) (WMD = 0.34; 95% CI: 0.04, 0.64), and interleukin-6 (IL-6) (WMD = −1.48; 95% CI: 2.96, −0.01). However, the results did not show any significant effect of cinnamon on malondialdehyde (MDA) (WMD = −0.47; 95% CI: 0.99, 0.05), C-reactive protein (CRP) (WMD = −1.33; 95% CI: 2.66, 0.00), and intercellular adhesion molecule 1 (ICAM-1) (WMD= 1.53, 95% CI: 12.03, 15.10).</div></div><div><h3>Conclusions</h3><div>The results of the studies included in this umbrella review support the usefulness of cinnamon consumption in modulating BP as well as improving TAC and IL-6 in metabolic disorders. Due to the limited number of studies, clinical diversity, and other limitations, more high-quality studies must be conducted to provide more precise and comprehensive recommendations.</div></div><div><h3>Registration number</h3><div>PROSPERO, CRD42023487350.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142190853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The OMNIVEG STUDY: Health outcomes of shifting from a traditional to a vegan Mediterranean diet in healthy men. A controlled crossover trial OMNIVEG 研究：健康男性从传统地中海饮食转向素食的健康结果。对照交叉试验

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-23 DOI: 10.1016/j.numecd.2024.08.008

Miguel López-Moreno , Ujué Fresán , Juan Del Coso , Millán Aguilar-Navarro , María Teresa Iglesias López , Javier Pena-Fernández , Alejandro Muñoz , Jorge Gutiérrez-Hellín

Background and aim

The Mediterranean diet is a plant-based dietary pattern with well-established health benefits such as the reduced risk of cardiovascular disease. Additionally, incorporating more plant-based foods into a Mediterranean diet may provide further health benefits. The study aimed to assess the effect of shifting from a traditional Mediterranean diet to a vegan Mediterranean diet on cardiorespiratory fitness and lipid profile in physically active and healthy men.

Methods and Results

Participants underwent a baseline period with adhesion to the general patterns of the Mediterranean diet for three weeks and then they changed to an isocaloric vegan version of the Mediterranean diet for four weeks, with a 7-day washout period between diets. The shift from the traditional Mediterranean diet to the vegan Mediterranean diet required substituting animal-based foods with plant-based foods that contain comparable amounts of protein and fat. Fourteen participants with a mean age of 24.6 ± 7.0 years (range: 18–37 years), completed the study protocol. The change from the traditional to the vegan Mediterranean diet reduced blood concentration of total cholesterol (−22.6 mg/dl, p < 0.01, Effect size [ES] = 1.07) and low-density lipoprotein cholesterol (−12.8 mg/dl, p < 0.01, ES = 0.72). An inverse correlation was observed between the intake of dietary fibre and LDL-C (partial rho = −0.43, p = 0.040).

Conclusions

The adoption of a vegan Mediterranean diet with plant-based proteins and fats instead of the traditional Mediterranean diet improved several cardiometabolic health outcomes in physically active and healthy men.

Clinical Trial Registry

NCT06008886.

地中海饮食是一种以植物为基础的饮食模式，对健康的益处已得到证实，如降低心血管疾病的风险。此外，在地中海饮食中加入更多植物性食物可能会带来更多健康益处。这项研究旨在评估从传统地中海饮食转为素食地中海饮食对体力充沛的健康男性心肺功能和血脂状况的影响。参与者在基线期坚持地中海饮食的一般模式三周，然后改用等热量素食版地中海饮食四周，两种饮食之间有 7 天的缓冲期。从传统地中海饮食到素食地中海饮食的转变需要用蛋白质和脂肪含量相当的植物性食物代替动物性食物。14 名参与者完成了研究方案，他们的平均年龄为 24.6 ± 7.0 岁（18-37 岁）。从传统饮食到纯素地中海饮食的转变降低了血液中总胆固醇的浓度（-22.6 毫克/分升，< 0.01，效应大小 [ES] = 1.07）和低密度脂蛋白胆固醇的浓度（-12.8 毫克/分升，< 0.01，效应大小 [ES] = 0.72）。膳食纤维摄入量与低密度脂蛋白胆固醇之间呈负相关（partial rho = -0.43，p = 0.040）。采用以植物蛋白和脂肪为主的素食地中海饮食取代传统地中海饮食，可改善体力活动量大的健康男性的多项心脏代谢健康结果。NCT06008886。

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引用次数: 0

Comment on: Associations of disordered eating with the intestinal microbiota and short-chain fatty acids among young adults with type 1 diabetes 评论1型糖尿病青少年患者饮食紊乱与肠道微生物群和短链脂肪酸的关系

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-22 DOI: 10.1016/j.numecd.2024.08.013

Liqi Li, Yupeng Li

引用次数: 0

The role of Nutri-Score and NutrInform Battery in guiding the food choices of consumers with specific nutritional needs: A controlled study Nutri-Score 和 NutrInform 电池在指导有特殊营养需求的消费者选择食品方面的作用：对照研究

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2024-08-10 DOI: 10.1016/j.numecd.2024.08.007

Greta Castellini , Sara Bertorelli , Michele Carruba , Lorenzo M. Donini , Daniela Martini , Guendalina Graffigna

Background and aims

There is a significant knowledge gap regarding the effectiveness of front-of-pack labeling (FoPL) systems in helping food choices that meet specific nutritional requirements. This study sought to compare the effectiveness of the Nutri-Score (NS) and NutrInform Battery (NIB) labels in assisting consumers to select food products with low sodium or low saturated fat.

Methods and results

Utilizing a controlled experimental design, a sample of 1512 participants (aged 18–70, 50.8% females) was exposed to scenarios through computer-assisted web interviewing, where they selected food products suitable for people with suboptimal blood pressure or plasma cholesterol levels, labeled with either NS, NIB, or no label (blind). The NIB proved significantly more efficacious than NS in guiding participants towards making selections in better agreement with nutritional needs, for blood pressure or cholesterol control. Furthermore, the NIB was generally viewed more favorably, with participants rating it as more trustworthy, informative, and useful for the required task. Notably, younger participants, those with higher nutritional knowledge, and those less inclined towards intuitive or spontaneous decision-making demonstrated a greater propensity for making health-congruent food choices when using the NIB.

Conclusion

The findings suggest that the informative FoPL system, NIB, may offer greater advantages in addressing specific dietary requirements. This underscores the important role of FoPL systems in promoting public health and meeting diverse and specific consumer needs. Further research is needed to confirm these results in broader contexts and for additional health conditions.

关于包装前标签（FoPL）系统在帮助选择符合特定营养要求的食品方面的有效性，还存在很大的知识差距。本研究试图比较营养分数（NS）标签和营养信息电池（NIB）标签在帮助消费者选择低钠或低饱和脂肪食品方面的有效性。利用对照实验设计，1512 名参与者（年龄在 18-70 岁之间，50.8% 为女性）通过计算机辅助网络访谈进行了情景体验，在这些情景中，他们选择了适合血压或血浆胆固醇水平不达标者食用的食品，这些食品分别贴有 NS、NIB 或无标签（盲标）。事实证明，在指导参与者选择更符合营养需求的食品以控制血压或胆固醇方面，NIB 明显比 NS 更有效。此外，参与者普遍对 NIB 更有好感，认为它更值得信赖、信息量更大、对所需任务更有用。值得注意的是，年轻的参与者、营养知识水平较高的参与者以及不那么倾向于直觉或自发决策的参与者在使用 NIB 时更倾向于做出符合健康的食物选择。研究结果表明，信息丰富的 FoPL 系统 NIB 在满足特定饮食要求方面可能具有更大的优势。这强调了食品标签系统在促进公众健康、满足消费者多样化和特定需求方面的重要作用。要在更广泛的背景下和针对更多的健康状况确认这些结果，还需要进一步的研究。

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