Nutrition Metabolism and Cardiovascular Diseases最新文献_第2页

Sex- and metabolic-specific association between cumulative body mass index and incident chronic kidney disease: A prospective community-based cohort study 累积体重指数与慢性肾病发病之间的性别和代谢特异性关联：一项基于社区的前瞻性队列研究。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103790

Yingting Zuo , Zhang Xia , Shuohua Chen , Lulu Chu , Yijun Zhang , Yuhao Li , Manqi Zheng , Guozheng Xu , Yan He , Shouling Wu , Anxin Wang

Background and aim

Difference in metabolic status may cause inconsistent association between body mass index (BMI) and chronic kidney disease (CKD) in men and women. This study aimed to quantify sex-specific association between cumulative BMI (cumBMI) and incident CKD by different metabolic status.

Methods and results

Participants free of CKD from the Kailuan Study were followed biennially from baseline (June 2006 to October 2007) to December 2019. cumBMI was calculated by use of follow-up BMI and follow-up time and was divided into low weight (<18.5 kg/m²), normal weight (18.5–23.9 kg/m²), overweight (24–27.9 kg/m²), and obesity (≥28 kg/m²) according to Chinese criteria. Metabolic health was defined as the absence of hypertension, dyslipidemia, and diabetes at baseline. CKD was defined as having estimated glomerular filtration rate <60 mL/min/1.73 m². This study included 76984 participants, with a mean age of 50.0 ± 11.6 years and 80.0 % of men. Overweight (HR = 1.24, 95 % CI: 1.16–1.31) and obesity (HR = 1.94, 95 % CI: 1.77–2.12) were associated with higher risk of incident CKD in men regardless of metabolic status. Corresponding population attributable risk percentages for overweight and obesity were 10.3 % (95%CI: 7.1–12.9) and 12.7 % (95%CI: 10.6–14.7), respectively. However, low weight (HR = 1.56, 95 % CI: 1.05–2.30) and obesity (HR = 1.32, 95 % CI: 1.01–1.73) were associated with higher risk of incident CKD in metabolically healthy women but not in metabolically unhealthy women.

Conclusions

This study demonstrated sex- and metabolic-specific associations between BMI and CKD occurrence and advocates an individualized weight management strategy.

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引用次数: 0

Association between brachial-ankle pulse wave velocity, obesity-related indices, and the 10-year incident risk score of atherosclerotic cardiovascular disease: The rural Chinese cohort study 臂踝脉搏波速度、肥胖相关指标与动脉粥样硬化性心血管疾病10年事件风险评分之间的关系：中国农村队列研究

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103791

MinQi Gu , DongDong Zhang , YuYing Wu , Xi Li , JinLiang Liang , YaQin Su , Li Yang , TaiFeng Chen , BoTang Guo , Yang Zhao , XueRu Fu , LiuDing Wen , ChuXia Lu , YuKe Chen , WanHe Huang , Pei Qin , FuLan Hu , DongSheng Hu , Ming Zhang

Background and aims

Although existing evidence suggests that arterial stiffness and obesity impact cardiovascular health, limited studies have been conducted to explore the association between brachial-ankle pulse wave velocity (baPWV), obesity-related indices, and the risk of atherosclerotic cardiovascular disease (ASCVD).

Methods and results

The study participants were among those who completed the baPWV measurement at the second follow-up examination (during 2018–2020) of the Rural Chinese Cohort Study. Logistic regression models were employed to calculate odds ratios (ORs) and 95 % confidence intervals (CIs) of the 10-year incident risk score of ASCVD associated with baPWV and obesity-related indices. Mediation analysis was applied to investigate the role of baPWV in the obesity-induced 10-year incident risk score of ASCVD. A total of 1589 individuals, including 573 men and 1016 women, were included in the study. In logistic regression analyses, the highest quartile levels of baPWV and obesity-related indices all significantly increased the 10-year incident risk score of ASCVD compared to their corresponding lowest quartiles. The ORs (95%CIs) of ASCVD 10-year incident risk score risk were 4.21(2.55–6.94) for baPWV, 4.43(2.69–7.29) for METS-VF, 7.20(4.09–12.66) for CVAI, 3.38(2.12–5.38) for CI, and 2.40(1.54–3.75) for ABSI. The indirect effect of baPWV accounted for 5.85 %, 7.92 %, 14.56 %, and 5.08 % of the total effects for METS-VF, CVAI, CI, and ABSI, respectively.

Conclusion

This study found that elevated levels of both baPWV and obesity-related indices were associated with a higher 10-year incident risk score of ASCVD. Additionally, baPWV partially mediated the obesity-related increase in 10-year incident risk score of ASCVD.

背景和目的：尽管现有证据表明动脉僵硬和肥胖会影响心血管健康，但关于肱-踝脉波速度（baPWV）、肥胖相关指标和动脉粥样硬化性心血管疾病（ASCVD）风险之间关系的研究有限。方法和结果：研究参与者是在中国农村队列研究的第二次随访检查（2018-2020年）中完成baPWV测量的参与者。采用Logistic回归模型计算与baPWV和肥胖相关指数相关的ASCVD 10年事件风险评分的比值比（ORs）和95%置信区间（ci）。采用中介分析探讨baPWV在肥胖诱导的ASCVD 10年事件风险评分中的作用。共有1589人参与了这项研究，其中包括573名男性和1016名女性。在logistic回归分析中，与相应的最低四分位数相比，baPWV和肥胖相关指数的最高四分位数水平均显著增加了ASCVD的10年事件风险评分。ASCVD 10年事件风险评分风险的ORs （95%CI）分别为baPWV组4.21(2.55 ~ 6.94)，met - vf组4.43(2.69 ~ 7.29)，CVAI组7.20(4.09 ~ 12.66)，CI组3.38(2.12 ~ 5.38)，ABSI组2.40（1.54 ~ 3.75）。baPWV的间接效应分别占met - vf、CVAI、CI和ABSI总效应的5.85%、7.92%、14.56%和5.08%。结论：本研究发现，baPWV和肥胖相关指数的升高与ASCVD 10年事件风险评分升高有关。此外，baPWV部分介导了肥胖相关的ASCVD 10年事件风险评分升高。

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引用次数: 0

Introduction to the debate

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2025.103910

Claudio Borghi (Prof)

引用次数: 0

Novel metabolic indicators and the risk of cardiovascular disease in patients with hypertension: A primary-care cohort study 新的代谢指标与高血压患者罹患心血管疾病的风险：一项初级保健队列研究。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.09.019

Deliang Lv , Zhen Liu , Xiaobing Wu , Fengzhu Xie , Qinggang Shang , Wei Xie , Ziyang Zhang , Zhiguang Zhao

Background and aims

Data are limited on whether several easily measured indices serve as effective tools for Cardiovascular disease (CVD) risk assessment in hypertensive patients. This study aimed to assess the associations of metabolic score for insulin resistance (METS-IR), lipid accumulation product (LAP), and visceral adiposity index (VAI) with CVD risk in hypertensive patients.

Methods and results

Our data were drawn from the medical records of primary-care institutions in China. The present study included 306,680 individuals with hypertension attending primary healthcare centers. Cox regression analyses were applied to assess the associations of novel metabolic indicators with the risk of CVD. During a median follow-up of 1.98 years, 5820 participants developed CVD. When comparing with the lowest quartile of the indices, the highest quartile of METS-IR, LAP, and VAI was associated with 1.25-fold (95 % CI: 1.16–1.35), 1.15-fold (95 % CI: 1.05–1.25), and 1.19-fold (95 % CI: 1.10–1.28) risk of CVD after adjusting for potential confounders.

Conclusion

This study provided additional evidence that novel metabolic indicators like METS-IR, LAP, and VAI were associated with the risk of CVD. These results suggest that proactive assessment of visceral adiposity and insulin resistance could be helpful for the effective clinical management of the hypertensive population.

背景和目的：关于几种易于测量的指数是否可作为高血压患者心血管疾病（CVD）风险评估的有效工具，相关数据十分有限。本研究旨在评估胰岛素抵抗代谢评分（METS-IR）、脂质累积乘积（LAP）和内脏脂肪指数（VAI）与高血压患者心血管疾病风险的关联：我们的数据来自中国基层医疗机构的医疗记录。本研究纳入了 306 680 名在基层医疗机构就诊的高血压患者。采用 Cox 回归分析评估了新的代谢指标与心血管疾病风险的相关性。在1.98年的中位随访期间，5820名参与者发生了心血管疾病。与指数最低四分位数相比，调整潜在混杂因素后，METS-IR、LAP和VAI的最高四分位数分别与1.25倍（95 % CI：1.16-1.35）、1.15倍（95 % CI：1.05-1.25）和1.19倍（95 % CI：1.10-1.28）的心血管疾病风险相关：本研究提供了更多证据，证明METS-IR、LAP和VAI等新型代谢指标与心血管疾病风险相关。这些结果表明，主动评估内脏脂肪和胰岛素抵抗有助于对高血压人群进行有效的临床管理。

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引用次数: 0

Sleep: The silent hero in cardiometabolic health 睡眠：心脏代谢健康中沉默的英雄。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.10.020

Jean-Philippe Chaput , Saverio Stranges

The essential role of sleep in overall health is increasingly recognized, yet it remains underemphasized in both clinical and public health contexts. Despite extensive research linking poor sleep health to chronic conditions such as cardiovascular disease, type 2 diabetes, and cognitive decline, sleep health is not routinely assessed or integrated into standard care practices. Sleep problems, including insomnia, sleep apnea, and poor sleep quality, are prevalent globally, affecting over 30 % of the population and contributing to significant public health burdens like cardiometabolic disease, mental health disorders and multimorbidity. The economic implications are substantial, with insufficient sleep imposing significant societal and financial costs worldwide. Recognizing this, recent initiatives like the American Heart Association's inclusion of sleep in the Life's Essential 8 framework highlight the importance of sleep in cardiometabolic health. Integrating sleep into clinical and public health strategies is crucial, due to the wide-ranging impact of sleep on cardiometabolic health. Social, environmental, and demographic factors also play significant roles in sleep health, with lower socioeconomic groups and women often experiencing poorer sleep, further exacerbating health disparities. Adopting a life course approach and promoting healthy sleep behaviors early in life are essential for mitigating long-term cardiometabolic risks. Effective evidence-based strategies for improving sleep behaviors and cardiometabolic health, beyond addressing sleep disorders, include prioritizing sleep hygiene, managing stress, promoting physical activity, maintaining a healthy diet, and reducing substance use, all of which contribute to overall well-being. In conclusion, incorporating sleep health into routine cardiometabolic risk stratification, prevention, and management is essential for improving overall health outcomes.

人们越来越认识到睡眠在整体健康中的重要作用，但在临床和公共卫生环境中仍未得到重视。尽管广泛的研究将睡眠健康状况不佳与心血管疾病、2型糖尿病和认知能力下降等慢性疾病联系起来，但睡眠健康状况并没有被常规评估或纳入标准护理实践。包括失眠、睡眠呼吸暂停和睡眠质量差在内的睡眠问题在全球普遍存在，影响了30%以上的人口，并造成了严重的公共卫生负担，如心脏代谢疾病、精神健康障碍和多种疾病。睡眠不足对经济的影响是巨大的，在世界范围内造成了巨大的社会和经济成本。认识到这一点，最近的一些倡议，比如美国心脏协会将睡眠纳入了生命的基本框架，强调了睡眠对心脏代谢健康的重要性。由于睡眠对心脏代谢健康的广泛影响，将睡眠纳入临床和公共卫生战略至关重要。社会、环境和人口因素也在睡眠健康中发挥重要作用，社会经济地位较低的群体和妇女往往睡眠较差，进一步加剧了健康差距。在生命早期采用生命历程方法和促进健康的睡眠行为对于减轻长期心脏代谢风险至关重要。除了解决睡眠障碍之外，改善睡眠行为和心脏代谢健康的有效循证策略还包括优先考虑睡眠卫生、管理压力、促进体育活动、保持健康饮食和减少物质使用，所有这些都有助于整体健康。总之，将睡眠健康纳入常规心脏代谢风险分层、预防和管理对改善整体健康结果至关重要。

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引用次数: 0

Predictive value of nutritional scores in non-valvular atrial fibrillation patients: Insights from the AFTER-2 study 营养评分在非瓣膜性房颤患者中的预测价值：来自AFTER-2研究的见解

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103794

Serdar Söner , Tuncay Güzel , Adem Aktan , Raif Kılıç , Bayram Arslan , Muhammed Demir , Hamdullah Güzel , Ercan Taştan , Metin Okşul , Adnan Duha Cömert , Faruk Ertaş

Background and aim

Many scoring systems are used to evaluate malnutrition, but there is no consensus on which scoring system would be more appropriate. We aimed to investigate the effect of malnutrition in patients with non-valvular atrial fibrillation (NVAF) and to compare three scoring systems.

Methods and results

A total of 2592 patients with non-valvular AF from 35 different centers in Turkey were included in this prospective study. All participants were divided into two groups: 761 patients who died and 1831 patients who were alive. The malnutrition status of all participants was evaluated with three scoring systems. The primary outcome was all-cause mortality. The mean age of the population was 68.7 ± 11.1 years, and 55.5 % were female. According to Cox regression analysis, the geriatric nutritional risk index (GNRI) (HR = 0.989, 95 % CI: 0.982–0.997, p = 0.007), controlling nutritional status (CONUT) score (HR = 1.121, 95 % CI: 1.060–1.185, p < 0.001), and prognostic nutritional index (PNI) (HR = 0.980, 95 % CI: 0.962–0.999, p = 0.036) were found to be significant mortality predictors. ROC curve analysis indicated GNRI (AUC = 0.568), CONUT (AUC = 0.572), and PNI (AUC = 0.547) had moderate predictive values. Kaplan-Meier analysis showed that increasing the risk class based on GNRI (p < 0.001) and CONUT (p < 0.001) was associated with decreased survival, while PNI staging had no statistically significant effect (p = 0.266).

Conclusions

Malnutrition, determined by three scoring systems, was found to be an independent predictor of all-cause mortality in NVAF patients. Nutritional examination may provide useful information for prognosis and risk stratification in patients with NVAF.

背景和目的：许多评分系统用于评估营养不良，但没有共识的评分系统将是更合适的。我们的目的是研究营养不良对非瓣膜性心房颤动（NVAF）患者的影响，并比较三种评分系统。方法和结果：来自土耳其35个不同中心的2592例非瓣膜性房颤患者被纳入这项前瞻性研究。所有参与者被分为两组：761名死亡患者和1831名活着的患者。所有参与者的营养不良状况用三种评分系统进行评估。主要结局为全因死亡率。平均年龄为68.7±11.1岁，女性占55.5%。根据Cox回归分析，老年营养风险指数（GNRI）（HR = 0.989, 95% CI: 0.982 ~ 0.997, p = 0.007）、控制营养状况（CONUT）评分（HR = 1.121, 95% CI: 1.060 ~ 1.185, p）是NVAF患者全因死亡率的独立预测因子。营养检查可以为非瓣膜性房颤患者的预后和风险分层提供有用的信息。

{"title":"Predictive value of nutritional scores in non-valvular atrial fibrillation patients: Insights from the AFTER-2 study","authors":"Serdar Söner , Tuncay Güzel , Adem Aktan , Raif Kılıç , Bayram Arslan , Muhammed Demir , Hamdullah Güzel , Ercan Taştan , Metin Okşul , Adnan Duha Cömert , Faruk Ertaş","doi":"10.1016/j.numecd.2024.103794","DOIUrl":"10.1016/j.numecd.2024.103794","url":null,"abstract":"<div><h3>Background and aim</h3><div>Many scoring systems are used to evaluate malnutrition, but there is no consensus on which scoring system would be more appropriate. We aimed to investigate the effect of malnutrition in patients with non-valvular atrial fibrillation (NVAF) and to compare three scoring systems.</div></div><div><h3>Methods and results</h3><div>A total of 2592 patients with non-valvular AF from 35 different centers in Turkey were included in this prospective study. All participants were divided into two groups: 761 patients who died and 1831 patients who were alive. The malnutrition status of all participants was evaluated with three scoring systems. The primary outcome was all-cause mortality. The mean age of the population was 68.7 ± 11.1 years, and 55.5 % were female. According to Cox regression analysis, the geriatric nutritional risk index (GNRI) (HR = 0.989, 95 % CI: 0.982–0.997, p = 0.007), controlling nutritional status (CONUT) score (HR = 1.121, 95 % CI: 1.060–1.185, p < 0.001), and prognostic nutritional index (PNI) (HR = 0.980, 95 % CI: 0.962–0.999, p = 0.036) were found to be significant mortality predictors. ROC curve analysis indicated GNRI (AUC = 0.568), CONUT (AUC = 0.572), and PNI (AUC = 0.547) had moderate predictive values. Kaplan-Meier analysis showed that increasing the risk class based on GNRI (p < 0.001) and CONUT (p < 0.001) was associated with decreased survival, while PNI staging had no statistically significant effect (p = 0.266).</div></div><div><h3>Conclusions</h3><div>Malnutrition, determined by three scoring systems, was found to be an independent predictor of all-cause mortality in NVAF patients. Nutritional examination may provide useful information for prognosis and risk stratification in patients with NVAF.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 3","pages":"Article 103794"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of novel inflammatory and metabolic markers with mortality in individuals with overweight and obesity

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2025.103859

Abdul-Quddus Mohammed , Lu Liu , Jiasuer Alifu , Guoqing Yin , Wen Zhang , Yawei Xu , Fuad A. Abdu , Wenliang Che

Background and aims

Stress hyperglycemia ratio (SHR) and pan-immune-inflammation value (PIV) are novel prognostic markers associated with metabolic changes and chronic inflammation, but their association with mortality risk in individuals with overweight and obesity remains unknown. We aimed to investigate impact of SHR and PIV on mortality risk in individuals with overweight and obesity.

Methods and results

This cohort study included 16,703 U S adults with overweight and obesity. SHR and PIV were estimated, and Cox regression, ROC, and Kaplan-Meier curves analyzed their associations with all-cause and cause-specific mortality. Subgroup and interaction analyses tested SHR and PIV consistency. Over a median follow-up of 110 months, there were 2432 all-cause deaths (14.6 %), including 677 cardiovascular, 577 cancer, and 130 cerebrovascular deaths. Participants were categorized by optimal SHR (≥1.038 or <1.038) and PIV (≥301 or <301) cutoffs. High SHR was associated with higher overall and cause-specific mortality (log-rank p < 0.001). High PIV was linked to increased risks of overall, cardiovascular, and cancer mortality (log-rank p < 0.001). Multivariate Cox models showed elevated SHR was associated with increased all-cause, cardiovascular, and cancer mortality (HR:1.59; 95%CI: 1.34–1.89; HR:1.45; 95%CI: 1.03–2.04; HR:1.66; 95%CI: 1.15–2.38, respectively). Elevated PIV was linked to higher all-cause and cardiovascular mortality (HR: 1.18; 95%CI: 1.02–1.37; HR:1.35; 95%CI: 1.02–1.79, respectively). Poorer survival was noted in obesity + high SHR and overweight + high PIV subgroups (log-rank p < 0.001).

Conclusions

Elevated SHR and PIV are significant predictors of increased all-cause and cause-specific mortality in individuals with overweight and obesity.

{"title":"Association of novel inflammatory and metabolic markers with mortality in individuals with overweight and obesity","authors":"Abdul-Quddus Mohammed , Lu Liu , Jiasuer Alifu , Guoqing Yin , Wen Zhang , Yawei Xu , Fuad A. Abdu , Wenliang Che","doi":"10.1016/j.numecd.2025.103859","DOIUrl":"10.1016/j.numecd.2025.103859","url":null,"abstract":"<div><h3>Background and aims</h3><div>Stress hyperglycemia ratio (SHR) and pan-immune-inflammation value (PIV) are novel prognostic markers associated with metabolic changes and chronic inflammation, but their association with mortality risk in individuals with overweight and obesity remains unknown. We aimed to investigate impact of SHR and PIV on mortality risk in individuals with overweight and obesity.</div></div><div><h3>Methods and results</h3><div>This cohort study included 16,703 U S adults with overweight and obesity. SHR and PIV were estimated, and Cox regression, ROC, and Kaplan-Meier curves analyzed their associations with all-cause and cause-specific mortality. Subgroup and interaction analyses tested SHR and PIV consistency. Over a median follow-up of 110 months, there were 2432 all-cause deaths (14.6 %), including 677 cardiovascular, 577 cancer, and 130 cerebrovascular deaths. Participants were categorized by optimal SHR (≥1.038 or <1.038) and PIV (≥301 or <301) cutoffs. High SHR was associated with higher overall and cause-specific mortality (log-rank p < 0.001). High PIV was linked to increased risks of overall, cardiovascular, and cancer mortality (log-rank p < 0.001). Multivariate Cox models showed elevated SHR was associated with increased all-cause, cardiovascular, and cancer mortality (HR:1.59; 95%CI: 1.34–1.89; HR:1.45; 95%CI: 1.03–2.04; HR:1.66; 95%CI: 1.15–2.38, respectively). Elevated PIV was linked to higher all-cause and cardiovascular mortality (HR: 1.18; 95%CI: 1.02–1.37; HR:1.35; 95%CI: 1.02–1.79, respectively). Poorer survival was noted in obesity + high SHR and overweight + high PIV subgroups (log-rank p < 0.001).</div></div><div><h3>Conclusions</h3><div>Elevated SHR and PIV are significant predictors of increased all-cause and cause-specific mortality in individuals with overweight and obesity.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 3","pages":"Article 103859"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review of dietary assessment methods used for South Asian migrants in high-income host countries

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103795

Purva Gulyani , Sabrina Gupta , Ashley H. Ng , Gina Trakman

Aim

The increased risk of chronic diseases and migration to high-income countries in South Asians has been well established. Considering exposure to changing dietary intake and lifestyle upon migration, accurate nutrition assessment is crucial in this population. The present review aims to summarise dietary assessment methods and nutrient databases for South Asian (SA) migrants in high-income countries.

Data Synthesis

A systematic search of Medline, Web of Sciences, Embase, CINHAL and Cochrane Central Library databases was conducted in August 2023. Eligible studies were critically appraised using Joanna Briggs Institute Critical Appraisal Tools. Data was extracted using a purpose-built spreadsheet. This systematic review has been registered with PROSPERO (Reg ID: CRD42021274929).

Conclusions

A total of 12991 studies were identified, of which 46 met the eligibility criteria. Dietary assessment methods were categorised as newly validated, previously validated, and not validated. Only ten studies used a validated culturally appropriate dietary assessment tool. This review shows that FFQ and 24-hour (24hr) dietary recall are the most utilised dietary assessment tools for SA migrants. The findings highlight the limited culturally appropriate dietary assessment tools available for SA migrants. Specific design and validation issues, such as cultural specificity, were identified that researchers should consider when developing new nutritional assessment tools for SA migrants.

{"title":"A systematic review of dietary assessment methods used for South Asian migrants in high-income host countries","authors":"Purva Gulyani , Sabrina Gupta , Ashley H. Ng , Gina Trakman","doi":"10.1016/j.numecd.2024.103795","DOIUrl":"10.1016/j.numecd.2024.103795","url":null,"abstract":"<div><h3>Aim</h3><div>The increased risk of chronic diseases and migration to high-income countries in South Asians has been well established. Considering exposure to changing dietary intake and lifestyle upon migration, accurate nutrition assessment is crucial in this population. The present review aims to summarise dietary assessment methods and nutrient databases for South Asian (SA) migrants in high-income countries.</div></div><div><h3>Data Synthesis</h3><div>A systematic search of Medline, Web of Sciences, Embase, CINHAL and Cochrane Central Library databases was conducted in August 2023. Eligible studies were critically appraised using Joanna Briggs Institute Critical Appraisal Tools. Data was extracted using a purpose-built spreadsheet. This systematic review has been registered with PROSPERO (Reg ID: CRD42021274929).</div></div><div><h3>Conclusions</h3><div>A total of 12991 studies were identified, of which 46 met the eligibility criteria. Dietary assessment methods were categorised as newly validated, previously validated, and not validated. Only ten studies used a validated culturally appropriate dietary assessment tool. This review shows that FFQ and 24-hour (24hr) dietary recall are the most utilised dietary assessment tools for SA migrants. The findings highlight the limited culturally appropriate dietary assessment tools available for SA migrants. Specific design and validation issues, such as cultural specificity, were identified that researchers should consider when developing new nutritional assessment tools for SA migrants.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 3","pages":"Article 103795"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is isocaloric intermittent fasting superior to calorie restriction? A systematic review and meta-analysis of RCTs 等热量间歇性禁食优于热量限制吗？随机对照试验的系统回顾和荟萃分析。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103805

Mohammed Hamsho , Wijdan Shkorfu , Yazan Ranneh , Abdulmannan Fadel

Background and aim

Intermittent fasting (IF) has been demonstrated to enhance human health through several mechanisms. However, it is still unclear whether those health benefits are independent of caloric restriction (CR)-induced weight loss. This systematic review and meta-analysis aimed to compare isocaloric IF and CR regarding anthropometric measurements, adherence, metabolic profile, inflammatory biomarkers, and adipokines in adults and elderlies.

Methods and results

Comprehensive research was conducted usin four major databases including Embase, PubMed, Scopus, and Google Scholar without date restriction. Mean differences of the change from baseline ± change SD were calculated as the differences between IF and CR groups. Subgroup analysis was performed according to intervention duration (short-, medium-, and long-term). To determine the reliability of our findings, GRADE assessment was performed. As a result, 20 RCTs were included in this systematic review and meta-analysis. IF groups had significant reductions in fat mass (kg) (P = 0.006) and Interleukin-6 (P < 0.00001) in the short term and fat mass (%) (P = 0.0002), waist circumference (P = 0.005), fasting blood insulin (P < 0.00001) and HOMA-IR (P = 0.04) in the long term. CR groups had significantly lower hunger (P = 0.003), fatigue (P = 0.04), and TG (P = 0.03).

Conclusions

IF may be an effective alternative to CR but is not superior to CR in enhancing human health. Due to the low number of long-term studies, future studies should focus on conducting longitudinal randomized trials comparing IF and CR in different populations, age groups, and IF patterns.

背景和目的：间歇性禁食（IF）已被证明通过几种机制增强人体健康。然而，目前尚不清楚这些健康益处是否独立于热量限制（CR）引起的体重减轻。本系统综述和荟萃分析旨在比较成人和老年人的等热量IF和CR在人体测量、依从性、代谢谱、炎症生物标志物和脂肪因子方面的差异。方法与结果：采用Embase、PubMed、Scopus、谷歌Scholar四大数据库进行综合研究，无资料限制。计算IF组与CR组之间的基线变化±变化SD的平均差异。根据干预持续时间（短期、中期和长期）进行亚组分析。为了确定研究结果的可靠性，我们进行了GRADE评估。因此，本系统综述和荟萃分析纳入了20项随机对照试验。IF组显著降低脂肪质量（kg）（P = 0.006）和白细胞介素-6 (P)。结论：IF可能是CR的有效替代品，但在促进人体健康方面并不优于CR。由于长期研究的数量较少，未来的研究应侧重于进行纵向随机试验，比较不同人群、年龄组和IF模式中的IF和CR。

{"title":"Is isocaloric intermittent fasting superior to calorie restriction? A systematic review and meta-analysis of RCTs","authors":"Mohammed Hamsho , Wijdan Shkorfu , Yazan Ranneh , Abdulmannan Fadel","doi":"10.1016/j.numecd.2024.103805","DOIUrl":"10.1016/j.numecd.2024.103805","url":null,"abstract":"<div><h3>Background and aim</h3><div>Intermittent fasting (IF) has been demonstrated to enhance human health through several mechanisms. However, it is still unclear whether those health benefits are independent of caloric restriction (CR)-induced weight loss. This systematic review and meta-analysis aimed to compare isocaloric IF and CR regarding anthropometric measurements, adherence, metabolic profile, inflammatory biomarkers, and adipokines in adults and elderlies.</div></div><div><h3>Methods and results</h3><div>Comprehensive research was conducted usin four major databases including Embase, PubMed, Scopus, and Google Scholar without date restriction. Mean differences of the change from baseline ± change SD were calculated as the differences between IF and CR groups. Subgroup analysis was performed according to intervention duration (short-, medium-, and long-term). To determine the reliability of our findings, GRADE assessment was performed. As a result, 20 RCTs were included in this systematic review and meta-analysis. IF groups had significant reductions in fat mass (kg) (P = 0.006) and Interleukin-6 (P < 0.00001) in the short term and fat mass (%) (P = 0.0002), waist circumference (P = 0.005), fasting blood insulin (P < 0.00001) and HOMA-IR (P = 0.04) in the long term. CR groups had significantly lower hunger (P = 0.003), fatigue (P = 0.04), and TG (P = 0.03).</div></div><div><h3>Conclusions</h3><div>IF may be an effective alternative to CR but is not superior to CR in enhancing human health. Due to the low number of long-term studies, future studies should focus on conducting longitudinal randomized trials comparing IF and CR in different populations, age groups, and IF patterns.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 3","pages":"Article 103805"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal obesity and cardiometabolic risk markers: A comparative analysis of waist circumference, dual-energy X-ray absorptiometry, and magnetic resonance imaging techniques 腹部肥胖和心脏代谢危险标志物：腰围、双能x线吸收仪和磁共振成像技术的比较分析。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Nutrition Metabolism and Cardiovascular Diseases

Pub Date : 2025-03-01 DOI: 10.1016/j.numecd.2024.103801

Giulianna Regeni Ruano , Guilherme Augusto Nogueira , Prince Dadson , Sandra R.G. Ferreira , Marcelo Tatit Sapienza , Licio A. Velloso , Milena Monfort-Pires

Background and aims

This study compares three methods to determine central adiposity (waist circumference –WC - and visceral adipose tissue – VAT - estimated by dual-energy x-ray absorptiometry – DXA, and by magnetic resonance imaging - MRI) in their ability to predict increases in cardiometabolic risk (CMR) markers in young individuals. We examined their associations with CMR in 47 men and women aged 25–40.

Methods and results

VAT mass was assessed using DXA and MRI. Blood samples were analyzed for CMR markers. Associations between central adiposity measurements and CMR factors were analyzed using Spearman's correlation coefficient, and the ability of these three central adiposity measurements to detect increased CMR was compared using receiver operating characteristic (ROC) curves. Similar to what was observed for the MRI-DXA and VAT-DXA, WC showed strong correlations with LDL-c and triglycerides (TG) and an inverse correlation with HDL-c (rho = −0.657 MRI, rho = −0.628 DXA, and rho = −0.604 WC, p < 0.01). On the other hand, only MRI-VAT and WC were associated with insulin and HOMA-IR (rho = 0.341 MRI and rho = 0.421 WC, p < 0.01). Central adiposity measurements were negatively associated with cold-induced ¹⁸F-FDG uptake in subcutaneous adipose tissue and positively associated with VAT TG content. No significant differences were observed when comparing the three central adiposity measurements in ROC curve analysis, and all measurements could predict increases in CMR markers and the combined CMR index.

Conclusions

This study reinforces the importance of using WC to assess increases in CMR markers among young adults. Given its practicality and efficacy, WC should be recommended in health centers to assess CMR risk.

背景和目的：本研究比较了三种确定中心性肥胖的方法（腰围- wc -和内脏脂肪组织- VAT -通过双能x线吸收仪- DXA和磁共振成像- MRI估计）预测年轻人心脏代谢风险（CMR）标志物增加的能力。我们在47名25-40岁的男性和女性中研究了它们与CMR的关系。方法和结果：采用DXA和MRI评估VAT质量。对血液样本进行CMR标记物分析。使用Spearman相关系数分析中心性肥胖测量与CMR因素之间的相关性，并使用受试者工作特征（ROC）曲线比较这三种中心性肥胖测量检测CMR增加的能力。与MRI-DXA和VAT-DXA的观察结果相似，WC与LDL-c和甘油三酯（TG）有很强的相关性，与HDL-c呈负相关(rho = -0.657 MRI, rho = -0.628 DXA和rho = -0.604 WC， p18f - fdg在皮下脂肪组织中的摄取，与VAT TG含量呈正相关。在ROC曲线分析中，比较三种中心肥胖测量值无显著差异，所有测量值均可预测CMR标记物和综合CMR指数的增加。结论：本研究强调了使用WC评估年轻人CMR标志物增加的重要性。鉴于其实用性和有效性，卫生中心应推荐使用WC来评估CMR风险。

{"title":"Abdominal obesity and cardiometabolic risk markers: A comparative analysis of waist circumference, dual-energy X-ray absorptiometry, and magnetic resonance imaging techniques","authors":"Giulianna Regeni Ruano , Guilherme Augusto Nogueira , Prince Dadson , Sandra R.G. Ferreira , Marcelo Tatit Sapienza , Licio A. Velloso , Milena Monfort-Pires","doi":"10.1016/j.numecd.2024.103801","DOIUrl":"10.1016/j.numecd.2024.103801","url":null,"abstract":"<div><h3>Background and aims</h3><div>This study compares three methods to determine central adiposity (waist circumference –WC - and visceral adipose tissue – VAT - estimated by dual-energy x-ray absorptiometry – DXA, and by magnetic resonance imaging - MRI) in their ability to predict increases in cardiometabolic risk (CMR) markers in young individuals. We examined their associations with CMR in 47 men and women aged 25–40.</div></div><div><h3>Methods and results</h3><div>VAT mass was assessed using DXA and MRI. Blood samples were analyzed for CMR markers. Associations between central adiposity measurements and CMR factors were analyzed using Spearman's correlation coefficient, and the ability of these three central adiposity measurements to detect increased CMR was compared using receiver operating characteristic (ROC) curves. Similar to what was observed for the MRI-DXA and VAT-DXA, WC showed strong correlations with LDL-c and triglycerides (TG) and an inverse correlation with HDL-c (rho = −0.657 MRI, rho = −0.628 DXA, and rho = −0.604 WC, p < 0.01). On the other hand, only MRI-VAT and WC were associated with insulin and HOMA-IR (rho = 0.341 MRI and rho = 0.421 WC, p < 0.01). Central adiposity measurements were negatively associated with cold-induced <sup>18</sup>F-FDG uptake in subcutaneous adipose tissue and positively associated with VAT TG content. No significant differences were observed when comparing the three central adiposity measurements in ROC curve analysis, and all measurements could predict increases in CMR markers and the combined CMR index.</div></div><div><h3>Conclusions</h3><div>This study reinforces the importance of using WC to assess increases in CMR markers among young adults. Given its practicality and efficacy, WC should be recommended in health centers to assess CMR risk.</div></div>","PeriodicalId":49722,"journal":{"name":"Nutrition Metabolism and Cardiovascular Diseases","volume":"35 3","pages":"Article 103801"},"PeriodicalIF":3.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0