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Dialysis Vintage and Symptom Burden in Hemodialysis: A Comprehensive Analysis. 透析年代与血液透析症状负担的综合分析。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70226
Shanshan Yan, Ya Wang, Zhenzhen Li, Duo Wang, Dongfang Yao

End-stage renal disease (ESRD) requires lifelong maintenance hemodialysis (MHD), and patients commonly experience a high symptom burden that affects their quality of life. This study explores the impact of dialysis vintage on symptom burden and quality of life in ESRD patients undergoing MHD. Our cross-sectional study of 213 Chinese hemodialysis patients found that symptom burden tended to increase with longer dialysis duration (Dialysis Symptom Index score from < 1 to > 10 years, p = 0.084), while urine output (p = 0.032) and Kt/V (p = 0.004) significantly decreased. Interestingly, quality of life improved across multiple domains as dialysis duration increased, including Kidney Disease Targeted Areas (KDTA) (p = 0.005), Symptom/Problem List (SPL) (p < 0.001), Effects of Kidney Disease (EKD) (p = 0.004), and Burden of Kidney Disease (BKD) (p < 0.001). These findings suggest that longer dialysis is associated with greater symptoms but also notable improvements in certain quality of life aspects. Personalized care is essential to address the evolving needs of long-term MHD patients and enhance their well-being.

终末期肾病(ESRD)需要终身维持性血液透析(MHD),患者通常经历高症状负担,影响其生活质量。本研究探讨透析时间对接受MHD的ESRD患者的症状负担和生活质量的影响。我们对213例中国血液透析患者的横断面研究发现,随着透析时间的延长,症状负担有增加的趋势(透析症状指数评分从10年开始,p = 0.084),而尿量(p = 0.032)和Kt/V (p = 0.004)显著降低。有趣的是,随着透析时间的增加,生活质量在多个领域得到改善,包括肾脏疾病目标区域(KDTA) (p = 0.005),症状/问题清单(SPL) (p = 0.005)
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引用次数: 0
Understanding the Barriers to Self-Management of Hypertension: A Qualitative Exploration of Patients' Lived Experiences. 了解高血压自我管理的障碍:对患者生活经历的定性探索。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70174
Jiaxin Wen, Jiaxu Zou, Ying Liu

This study adopted a qualitative design to explore lived experiences related to barriers in self-management among hypertensive patients. The study site was a tertiary general hospital in northeast China. Purposive sampling was used to select 12 patients hospitalized in four cardiovascular departments in the hospital. Semi-structured interviews were conducted to obtain information from patients between January 2021 and March 2021, and the data were stored using a digital recorder. Data management was accomplished by NVivo 12, and thematic approach was performed for data analysis. Three themes emerged from this study: (1) effect of individual beliefs on blood pressure, (2) challenges in self-management of the disease, and (3) insufficient resources support. The findings offer guidance for healthcare professionals to develop more effective self-management interventions to lower blood pressure and enhance self-management level for hypertensive patients. The results also provide evidence that can inform administrators and departments' supervisors in implementing supportive measures for self-management of hypertension.

本研究采用质性设计探讨高血压患者自我管理障碍的相关生活经历。研究地点为东北某三级综合医院。采用目的抽样的方法,选取该院4个心血管科住院的12例患者。在2021年1月至2021年3月期间进行了半结构化访谈,以获取患者的信息,并使用数字记录器存储数据。数据管理由NVivo 12完成,数据分析采用专题方法。从这项研究中出现了三个主题:(1)个人信仰对血压的影响,(2)疾病自我管理的挑战,(3)资源支持不足。研究结果可指导医护人员制定更有效的自我管理干预措施,降低高血压患者的血压,提高患者的自我管理水平。研究结果也为管理人员和部门主管实施高血压自我管理的支持措施提供了依据。
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引用次数: 0
Bridging the Evidence-Practice Gap in Hyperglycemia Management During Enteral Nutrition: A Multidimensional Implementation Study in Critically Ill Patients. 弥合肠内营养期间高血糖管理的证据与实践差距:一项危重患者的多维实施研究。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70178
Wenjun Yan, Yanxia Han, Chenying Qian, Yaxin Li, Zhi Zhao

Long-term hyperglycemia poses an elevated risk of infection, organ dysfunction, and increased mortality. Despite the availability of strategies for managing hyperglycemia, implementation effectiveness remains suboptimal. Therefore, this study investigates the factors hindering successful implementation and identifies potential change strategies. This study established evidence-based questions and formulated quality indicators. A baseline survey assessed existing practices. Subsequently, obstacle factors were analyzed using the Ottawa Model of Research Use, considering three dimensions: innovation, potential adopters, and practice environment; change strategies were then developed. The study revealed a significant gap between evidence and practice in hyperglycemia management during enteral nutrition in critically ill patients; adherence to 20 of 25 quality indicators was below 60%. Key obstacle factors included inadequate medical staff knowledge, a lack of standardized management processes, and the complexity of the evidence base. To address these challenges, the research team proposed intervention strategies including strengthening standardized hyperglycemia management protocols, establishing multidisciplinary teams, and providing systematic training. This study offers a framework for improving the quality of hyperglycemia management during enteral nutrition in critically ill patients and promoting the translation of evidence-based practice. Trial Registration: Fudan University Center for Evidence-Based Nursing: ER20240865.

长期高血糖会增加感染、器官功能障碍和死亡率增加的风险。尽管有治疗高血糖的策略,但实施效果仍不理想。因此,本研究调查了阻碍成功实施的因素,并确定了潜在的变革策略。本研究建立循证问题,制定质量指标。基线调查评估了现有的实践。随后,采用渥太华研究使用模型分析障碍因素,考虑三个维度:创新、潜在采用者和实践环境;随后制定了变革战略。该研究揭示了危重患者肠内营养期间高血糖管理的证据与实践之间存在显著差距;在25项质量指标中,有20项的依从性低于60%。主要障碍因素包括医务人员知识不足、缺乏标准化的管理程序以及证据基础的复杂性。针对这些挑战,研究小组提出了加强标准化高血糖管理方案、建立多学科团队、提供系统培训等干预策略。本研究为提高危重患者肠内营养期间高血糖管理质量和促进循证实践的转化提供了一个框架。试验注册号:复旦大学循证护理中心:ER20240865。
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引用次数: 0
A Systematic Review and Meta-Analysis of Barriers Affecting Early Ambulation in Older Patients After Hip Fracture Surgery. 影响髋部骨折术后老年患者早期活动障碍的系统回顾和荟萃分析。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70177
Jingru Chen, Xueyang Gan, Jie Song, Ling Gao, Mengqi Shao, Youting Wang, Yuan Gao

Hip fracture is a catastrophic traumatic injury for the older adults, early ambulation is crucial for recovery. Prior researchers explored a number of influencing factors, but there is still a pressing need for synthesizing the evidence. A systematic literature review was conducted for original studies by searching electronic databases included PubMed, Embase, CINAHL, Scopus, web of science and Cochrane Library from inception till July 2023. The odds ratio and 95% confidence interval were calculated for the combined risk factors using Review Manager 5.4. Finally, 2665 articles were initially assessed, and 26 studies were ultimately deemed eligible for inclusion in this meta-analysis, contributing a collective total of 18 698 subjects to the analysis. The following factors were showed strong association with early ambulation: age (OR: 1.04, 95% CI: 1.03-1.05); low pre-fracture functional level (OR: 1.39, 95% CI: 1.25-1.54); anemia (OR: 2.81, 95% CI: 1.79-4.42); vitamin D deficiency (OR: 2.73, 95% CI:1.64-4.56); poor nutritional status (OR:2.08, 95% CI: 1.56-2.77); cognitive impairment (OR: 1.16, 95% CI: 1.09-1.22); Charlson Comorbidity Index (OR: 0.80, 95% CI: 0.72-0.90); intertrochanteric fracture (OR: 3.24, 95% CI: 1.99-5.28). For patients presenting with the aforementioned influencing factors, targeted preventive approaches and management strategies should be employed to facilitate rapid postoperative recovery.

髋部骨折对老年人来说是一种灾难性的创伤性损伤,早期活动对康复至关重要。先前的研究人员探索了许多影响因素,但仍然迫切需要综合证据。通过检索PubMed、Embase、CINAHL、Scopus、web of science、Cochrane Library等电子数据库,对自成立至2023年7月的原创研究进行系统文献综述。使用Review Manager 5.4计算组合危险因素的优势比和95%置信区间。最终,2665篇文章被初步评估,26项研究最终被认为符合纳入本荟萃分析的条件,总共有18698名受试者参与了分析。以下因素与早期下床活动密切相关:年龄(OR: 1.04, 95% CI: 1.03-1.05);骨折前功能水平低(OR: 1.39, 95% CI: 1.25-1.54);贫血(OR: 2.81, 95% CI: 1.79-4.42);维生素D缺乏(OR: 2.73, 95% CI:1.64-4.56);营养状况差(OR:2.08, 95% CI: 1.56-2.77);认知障碍(OR: 1.16, 95% CI: 1.09-1.22);Charlson共病指数(OR: 0.80, 95% CI: 0.72-0.90);粗隆间骨折(OR: 3.24, 95% CI: 1.99-5.28)。对于存在上述影响因素的患者,应采取针对性的预防措施和管理策略,促进术后快速恢复。
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引用次数: 0
"No One Knows I Exist": A Qualitative Study Exploring the Experiences of Young People and Staff in UK Mental Health Hospitals. “没有人知道我的存在”:一项探讨英国精神卫生医院年轻人和工作人员经历的定性研究。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70224
William Murcott, Scott Weich, Andrew Thompson, Deborah L Biggerstaff

Supporting youth mental health is a priority; currently, one in 10 young people experience a mental health disorder. Accordingly, integrated youth health services are a focus for service development both in the United Kingdom and internationally. Less attention is given to inpatient settings and the experiences of young people who use them. This in-depth qualitative study aimed to understand the experiences of people aged 16-25 years, admitted to inpatient mental health settings, and the experiences of staff caring for them. Individual interviews with seven inpatient young people and three focus groups with staff (N = 27) were conducted. An Interpretative Phenomenological Analysis (IPA) methodology with a polyvocal design was used. Young people reported how the impact of restriction, lack of inclusion, information, and transparency affected their experiences. Relationships with other young people and staff were important while shared experiences were especially salient. Staff identified difficulties of working within a system divided into separate services while attempting to work flexibly with young people. Future practice needs to enhance relational, inclusive, and flexible working practices to optimize care delivery.

支持青少年心理健康是一项优先事项;目前,十分之一的年轻人患有精神疾病。因此,综合青年保健服务是联合王国和国际服务发展的重点。对住院环境和使用这些环境的年轻人的经历给予的关注较少。这项深入的定性研究旨在了解16-25岁的人的经验,入院的精神卫生机构,以及工作人员照顾他们的经验。对7名住院青年患者和3个工作人员焦点小组(N = 27)进行了个人访谈。本研究采用多声音设计的解释性现象学分析方法。年轻人报告了限制、缺乏包容、信息和透明度如何影响了他们的经历。与其他年轻人和工作人员的关系很重要,而分享经验尤为突出。工作人员发现,在一个分为不同服务的系统内工作,同时又试图灵活地与年轻人一起工作的困难。未来的实践需要加强关系,包容性和灵活的工作实践,以优化护理服务。
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引用次数: 0
The Ripple Effect of COVID-19: How Lockdown Regulations Shaped Antiretroviral Therapy Initiation Among People Living With HIV in Johannesburg. 2019冠状病毒病的连锁反应:约翰内斯堡封锁条例如何影响艾滋病毒感染者开始抗逆转录病毒治疗。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70235
N Nkadimeng, L Makhado, O P Netshisaulu

The COVID-19 pandemic has severely impacted global healthcare systems and significantly affected individuals living with HIV. In South Africa, where the HIV epidemic is prevalent, strict lockdown measures were introduced to curb COVID-19 transmission. This study explores the effects of these lockdown regulations on the initiation of antiretroviral therapy (ART) among HIV-positive individuals in Johannesburg. Employing a quantitative retrospective chart review design, the research analyzed ART initiation trends in Soweto before, during, and after the lockdowns using medical records from selected clinics in Region D. Data were collected with a checklist, and descriptive analysis was performed. The findings revealed a 40% decrease in ART initiation at community health centers (CHCs) during the lockdowns, compared to a 20% decrease in clinics. Additionally, clinics maintained a patient retention rate of 75%, whereas CHCs saw only 55%. These results highlight significant disparities in healthcare access and outcomes during the pandemic, indicating that COVID-19 threatens to reverse progress in the global HIV response, emphasizing the need for targeted interventions to sustain advancements in fighting HIV.

COVID-19大流行严重影响了全球卫生保健系统,并严重影响了艾滋病毒感染者。在艾滋病毒流行的南非,采取了严格的封锁措施来遏制COVID-19的传播。本研究探讨了这些封锁条例对约翰内斯堡艾滋病毒阳性个体开始抗逆转录病毒治疗(ART)的影响。该研究采用定量回顾性图表审查设计,利用d区选定诊所的医疗记录,分析了索韦托在封锁之前、期间和之后的抗逆转录病毒治疗启动趋势。研究结果显示,在封锁期间,社区卫生中心(CHCs)的抗逆转录病毒治疗起始率下降了40%,而诊所的起始率下降了20%。此外,诊所保持了75%的病人保留率,而中心只有55%。这些结果凸显了大流行期间在获得医疗服务和取得成果方面存在的巨大差异,表明COVID-19有可能逆转全球艾滋病毒应对工作取得的进展,强调需要采取有针对性的干预措施,以维持在抗击艾滋病毒方面取得的进展。
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引用次数: 0
Frailty, Nutrition, and Quality of Life in Urban-Dwelling Older Adults Facing Vulnerability: Observational Study in Primary Heath Care Settings in Underpopulated Areas. 在人口稀少地区的初级卫生保健机构中,面对脆弱性的城市居住老年人的脆弱、营养和生活质量观察研究
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70234
Kalyne Patrícia de Macêdo Rocha, Larissa Amorim Almeida, Nathaly da Luz Andrade, Mayara Priscilla Dantas Araújo, Andreia Luíza de Oliveira, Maria Eduarda Oliveira de Albuquerque, Matheus Medeiros de Oliveira, Estefane Beatriz Leite de Morais, Rafaela Carolini de Oliveira Távora, Carola Rosas, Maria Antónia Fernandes Caeiro Chora, Maria Laurência Grou Parreirinha Gemito, Bruno Araújo da Silva Dantas, Gilson de Vasconcelos Torres

To investigate the predictive relationships between frailty, nutritional factors, and Quality of Life (QoL) on the vulnerability of older adults enrolled in Primary Health Care (PHC) in an urban area. This was a cross-sectional study conducted with community-dwelling older adults. Participants receiving care in PHC in two Brazilian municipalities located in a sparsely populated region were recruited. The instruments used were Vulnerable Elders Survey (VES-13), Mini Nutritional Assessment (MNA), Edmonton Frailty Scale (EFS), and Medical Outcomes Study Short Form-36 (SF-36). Association analyses, Spearman's correlation, and binary logistic regression were used. A total of 323 individuals were included. Binary logistic regression revealed frailty (EFS) as the main predictor of vulnerability (R2 = 0.20; p < 0.001; OR = 1.35 [95% CI: 1.24-1.48]), with functional independence (R2 = 0.25; p < 0.001; OR = 3.9 [95% CI: 2.74-5.73]) and functional performance (R2 = 0.17; p < 0.001; OR = 3.21 [95% CI: 2.21-4.67]) being the domains that most strongly increased the odds of vulnerability. Impaired nutrition showed a consistent predictive association (R2 = 0.11; p < 0.001; OR = 0.82 [95% CI: 0.76-0.89]). Frailty and poor nutritional status were predictors of vulnerability, with particular emphasis on physical-functional aspects. QoL showed a moderate to strong correlation with vulnerability, especially in the physical domains.

目的:探讨老年人脆弱性、营养因素和生活质量(QoL)对城市初级卫生保健(PHC)老年人脆弱性的预测关系。这是一项对居住在社区的老年人进行的横断面研究。在位于人口稀少地区的两个巴西城市接受初级保健护理的参与者被招募。使用的工具有易受伤害长者调查(VES-13)、迷你营养评估(MNA)、埃德蒙顿虚弱量表(EFS)和医疗结果研究简表-36 (SF-36)。采用关联分析、Spearman相关和二元逻辑回归。共纳入323人。二元logistic回归分析显示,脆弱性(EFS)是易损性的主要预测因子(R2 = 0.20; p 2 = 0.25; p 2 = 0.17; p 2 = 0.11
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引用次数: 0
Development and Validation of the Women's Perceived Privacy in Infertility Treatment Scale. 不孕症治疗量表中女性感知隐私的开发与验证。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70221
İlknur Atasever, Çiğdem Yücel Özçırpan

This study aimed to develop and validate the Scale of Women's Privacy Perception in Infertility Treatment (SWPPIT) to assess privacy perceptions during infertility diagnosis and treatment. A methodological design was used in two phases. In phase one, scale items were developed through qualitative observations and interviews with women undergoing ART. In phase two, validity and reliability were tested on 370 women at a private IVF center. Construct validity was established via exploratory and confirmatory factor analyses, and reliability was assessed using Cronbach's alpha and test-retest methods. The SWPPIT revealed a single-factor structure, explaining 45.19% of the variance, with factor loadings between 0.30 and 0.87. It demonstrated high internal consistency (Cronbach's alpha = 0.949) and excellent test-retest reliability (r = 0.98, p < 0.001). The final scale comprises 37 items rated on a 5-point Likert scale. The SWPPIT is a reliable and valid tool for evaluating women's privacy perceptions in ART settings, enabling healthcare professionals to address privacy concerns and enhance patient-centered care.

本研究旨在开发并验证不孕不育治疗中女性隐私感知量表(SWPPIT),以评估不孕不育诊断和治疗过程中的隐私感知。方法设计分为两个阶段。在第一阶段,通过对接受抗逆转录病毒治疗的妇女进行定性观察和访谈,制定了量表项目。在第二阶段,对一家私人试管婴儿中心的370名妇女进行了有效性和可靠性测试。通过探索性和验证性因子分析建立结构效度,采用Cronbach's alpha和test-retest方法评估信度。SWPPIT表现为单因素结构,解释了45.19%的方差,因子负荷在0.30 ~ 0.87之间。它具有较高的内部一致性(Cronbach’s alpha = 0.949)和良好的重测信度(r = 0.98, p
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引用次数: 0
Treatment-Related Decision Fatigue in Patients With Recurrent Papillary Thyroid Cancer: A Qualitative Study. 复发性甲状腺乳头状癌患者治疗相关决策疲劳的定性研究
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70199
Yinwen Ding, Wen Wang, Qianqian Zhang, Xinyue Gu, Hui Zhang, Meiyan Qian, Guanghui Shi, Pingting Zhu

The purpose of this study was to explore the experience of treatment-related decision fatigue in patients with recurrent papillary thyroid cancer. Patients with recurrent papillary thyroid carcinoma who were followed up in thyroid surgery wards and outpatient clinics of three tertiary hospitals in Jiangsu Province were included in this study. Semi-structured interviews were conducted from January to April 2024. Inductive content analysis was used to identify themes. A total of 21 participants, aged 24-58 years, were interviewed. Two themes and six sub-themes were identified: manifestations of decision fatigue including impulsive decision making, hesitation, aggravation of negative emotions, and decision making is a burden; and consequences of decision fatigue including decision regret and delay in decision making. Our study identified the manifestations and adverse consequences of decision fatigue in patients with recurrent papillary thyroid cancer, and helped medical staff to identify and develop personalized interventions as early as possible to help patients make appropriate treatment decisions and improve the quality of decision-making and patient treatment outcomes.

本研究的目的是探讨复发性甲状腺乳头状癌患者治疗相关决策疲劳的经验。在江苏省三所三级医院甲状腺外科病房和门诊随访的复发性甲状腺乳头状癌患者为研究对象。半结构化访谈于2024年1月至4月进行。采用归纳性内容分析来确定主题。共有21名参与者接受了采访,年龄在24-58岁之间。结果表明:决策疲劳表现为冲动决策、犹豫决策、负性情绪加重决策、决策是负担决策;决策疲劳的后果包括决策后悔和决策延迟。本研究明确了复发性甲状腺乳头状癌患者决策疲劳的表现及不良后果,帮助医护人员及早发现并制定个性化干预措施,帮助患者做出合适的治疗决策,提高决策质量和患者治疗效果。
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引用次数: 0
Complementary Interventions Using Technology for Individuals With Infertility Using Assisted Reproductive Technology: A Scoping Review. 辅助生殖技术对不孕症患者的辅助干预:范围综述。
IF 1.6 3区 医学 Q2 NURSING Pub Date : 2025-09-01 DOI: 10.1111/nhs.70227
Jiwon Lee, Jaejin Kang, Jo Woon Seok

The global rise in infertility highlights the need for personalized informational and psychological support. Digital health technology offers a promising avenue; however, knowledge gaps remain regarding optimal delivery methods, outcomes, and limitations. This scoping review synthesizes recent evidence on complementary interventions using technology for individuals with infertility undergoing reproductive technology-assisted interventions and evaluates their effectiveness and limitations. Seven databases were systematically searched to identify studies published in English or Korean between 2000 and December 2023. The risk of bias was assessed using the Joanna Briggs Institute checklist, and data were synthesized using a standardized template. Of 1353 screened studies, 16 were selected, featuring interventions such as web-based programs, mobile applications, and online meetings. Positive outcomes were observed in knowledge, stress reduction, self-efficacy, coping, and dietary behaviors. However, mixed results were found for fertility-related stress, depression, and anxiety, with no significant improvements in fertility-related quality of life, health behaviors, and pregnancy rates. While digital interventions show promise, further research is needed to validate their effectiveness through large-scale randomized controlled trials and to develop standardized assessment tools for better implementation and evaluation.

全球不孕症的增加突出了对个性化信息和心理支持的需求。数字卫生技术提供了一条很有前途的途径;然而,关于最佳交付方法、结果和局限性的知识差距仍然存在。这篇范围综述综合了利用技术对接受生殖技术辅助干预的不孕症患者进行辅助干预的最新证据,并评估了其有效性和局限性。系统检索了7个数据库,以确定2000年至2023年12月期间用英语或韩语发表的研究。使用Joanna Briggs研究所的检查表评估偏倚风险,并使用标准化模板综合数据。在1353项筛选研究中,选择了16项,其干预措施包括基于网络的程序、移动应用程序和在线会议。在知识、压力减轻、自我效能、应对和饮食行为方面观察到积极的结果。然而,在与生育有关的压力、抑郁和焦虑方面,结果却喜忧参半,在与生育有关的生活质量、健康行为和怀孕率方面没有显著改善。虽然数字干预显示出希望,但需要进一步研究,通过大规模随机对照试验验证其有效性,并开发标准化评估工具,以便更好地实施和评估。
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引用次数: 0
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Nursing & Health Sciences
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