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Mathematical derivation and analysis of a mixture model of tumor growth 肿瘤生长混合模型的数学推导与分析
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-16 DOI: 10.1016/j.nonrwa.2025.104571
Giuseppe Cardone , Reine Gladys Noucheun , Carmen Perugia , Jean Louis Woukeng
We derive, through the periodic homogenization theory in thin heterogeneous domains, a 2D model consisting of Hele-Shaw equation coupled with the convective Cahn-Hilliard equation with non-constant mobility. The upscaled set of equations, which models in particular tumor growth, is then analyzed and we prove some regularity results. We heavily rely on the two-scale convergence concept in thin heterogeneous media associated to some Sobolev inequalities such as the Gagliardo-Nirenberg and Agmon inequalities to achieve our goal.
利用非恒定迁移率下的Hele-Shaw方程和对流Cahn-Hilliard方程,导出了一个由非恒定迁移率的Hele-Shaw方程和对流Cahn-Hilliard方程组成的二维模型。然后,我们对放大后的方程组进行了分析,并证明了一些规律性的结果。我们在很大程度上依赖于与Sobolev不等式(如Gagliardo-Nirenberg不等式和Agmon不等式)相关的薄异质介质中的双尺度收敛概念来实现我们的目标。
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引用次数: 0
Spatiotemporal patterns induced by nonlocal prey competition and prey-taxis in a diffusive Rosenzweig-MacArthur system 弥漫性Rosenzweig-MacArthur系统中非局部猎物竞争和猎物趋向性诱导的时空格局
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-15 DOI: 10.1016/j.nonrwa.2025.104561
Xinshan Dong , Ben Niu , Lin Wang
We investigate a diffusive Rosenzweig-MacArthur system that includes nonlocal prey competition and prey-taxis under Neumann boundary conditions. Initially, we establish the global existence and boundedness of solutions for arbitrary spatial dimensions and small prey-taxis sensitivity coefficient. Subsequently, we analyze the local stability of the constant steady-state solution. Using the Lyapunov-Schmidt reduction method, we explore several bifurcations near the positive constant steady-state: steady-state bifurcation, Hopf bifurcation, and their interaction. Finally, numerical simulations are performed to validate our theoretical findings and illustrate complex spatiotemporal patterns. By selecting appropriate parameters and initial conditions, our simulations reveal the coexistence of a pair of stable spatially nonhomogeneous steady-states and stable spatially homogeneous periodic solutions, which indicates the system exhibits tristability, that is, the coexistence of three distinct stable states. Moreover, our results demonstrate that transient patterns transition from spatially nonhomogeneous periodic solutions to spatially nonhomogeneous steady-state and spatially homogeneous periodic solutions.
在Neumann边界条件下,研究了一个包含非局部猎物竞争和猎物趋近性的扩散Rosenzweig-MacArthur系统。首先,我们建立了任意空间维度和小猎物趋向性灵敏度系数下解的整体存在性和有界性。随后,我们分析了常稳态解的局部稳定性。利用Lyapunov-Schmidt约简方法,探讨了正常稳态附近的几种分岔:稳态分岔、Hopf分岔及其相互作用。最后,进行了数值模拟来验证我们的理论发现,并说明了复杂的时空模式。通过选择合适的参数和初始条件,我们的模拟结果显示了一对稳定的空间非齐次稳态和稳定的空间齐次周期解共存,这表明系统具有三稳定性,即三种不同的稳定状态共存。此外,我们的结果证明了瞬态模式从空间非齐次周期解过渡到空间非齐次稳态和空间齐次周期解。
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引用次数: 0
Some qualitative properties of solution to a fractional thermo-viscoelastic system with nonlinear sources 非线性源分数阶热粘弹性系统溶液的一些定性性质
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-15 DOI: 10.1016/j.nonrwa.2025.104569
Nguyen Van Y , Le Cong Nhan , Le Xuan Truong
In the paper, we consider a fractional thermo-viscoelastic system with nonlinear sources and study some of its qualitative properties based on the interaction of the fractional viscoelastic and thermal damping with the external forces. By using the theory of linear Volterra differential-integral equations of convolution type and the Banach fixed point theorem, we first prove the local well-posedness and maximal regularity of the weak solution. Then by using the variational and potential well methods, we give a sufficient condition for the continuity in time of the local weak solution when it starts in the potential wells. Besides that the asymptotic behavior of global solution is also concerned, unlike the classical thermoelasticity where the total energy does not decays uniformly, since the effect of the fractional viscoelastic damping, we show that the total energy shall decay uniformly. In addition, its decay rate is given explicitly and optimally in the sense of Lasiecka et. al.[1]. Finally, since the presence of the nonlinear sources, we show that the blow-up phenomenon may occur in finite time provided that the solution starts outside the potential wells and the relaxation function is small in some sense. Also notice that the effect of the thermal damping is not enough to make the total energy decays to zero, but it could retards the blow-up phenomenon.
本文考虑具有非线性源的分数阶热粘弹性系统,并基于分数阶粘弹性和热阻尼与外力的相互作用,研究了它的一些定性性质。利用卷积型线性Volterra微分积分方程理论和Banach不动点定理,首次证明了弱解的局部适定性和极大正则性。然后利用变分方法和势井方法,给出了势井中局部弱解开始时在时间上连续的充分条件。此外,还考虑了整体解的渐近特性,与经典热弹性力学中总能量不均匀衰减不同,由于分数阶粘弹性阻尼的影响,我们证明了总能量均匀衰减。此外,它的衰减率在Lasiecka等人的意义上得到了明确和最优的给出。最后,由于非线性源的存在,我们证明了如果解从势阱外开始并且松弛函数在某种意义上较小,则爆破现象可能在有限时间内发生。同时注意到热阻尼的作用并不足以使总能量衰减到零,但它可以延缓爆炸现象。
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引用次数: 0
Traveling waves in a bacterial colony model 细菌菌落模型中的行波
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-15 DOI: 10.1016/j.nonrwa.2025.104577
Manjun Ma, Kaili Wang, Dan Li
This work is concerned with a nonlinear and non-monotonic reaction-diffusion system that models the dynamics of bacterial colonies with density-suppressed motility. We first establish the existence of global solutions and the attractivity of the uniform coexsitence state in a moving coordinate frame. Traveling waves are then transformed into fixed points of a mapping associated with an auxiliary system. By constructing upper and lower solutions, we next establish an invariant function space for this mapping. By using Schauder’s fixed point theorem, we derive implicit conditions for the existence of traveling waves. Through developing innovative analytical techniques, we further obtain explicit conditions that are corroborated by numerical computation and simulations of the considered bacterial colony model.
这项工作涉及一个非线性和非单调的反应扩散系统,该系统模拟了具有密度抑制运动的细菌菌落的动力学。首先在运动坐标系中建立了全局解的存在性和一致共存态的吸引性。然后将行波转换为与辅助系统相关联的映射的不动点。通过构造上解和下解,建立了该映射的不变函数空间。利用Schauder不动点定理,导出了行波存在的隐式条件。通过开发创新的分析技术,我们进一步获得了由数值计算和模拟所考虑的细菌菌落模型所证实的明确条件。
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引用次数: 0
Pattern dynamics in a reaction-diffusion predator-prey model with fear response delay 具有恐惧反应延迟的反应-扩散捕食者-猎物模型的模式动力学
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-13 DOI: 10.1016/j.nonrwa.2025.104574
Weidong Qin, Yunxian Dai, Doudou Lou
This paper investigates a delayed predator-prey model incorporating fear effects, prey refuge, Crowley-Martin type functional response, and cross-diffusion. First, we analyze the existence and stability of the positive equilibrium of the non-delay model. Then, we investigate the conditions for the occurrence of Turing instability in the delayed model. The amplitude equation is derived using the multiple-scale perturbation method, revealing the relationship between pattern selection and system parameters. Meanwhile, some numerical simulations are conducted to validate the accuracy of the theoretical analysis. The results demonstrate that varying control parameters can induce diverse patterns, including spots, stripes, and mixed patterns. Additionally, we find that the fear response delay affects the stabilization time of patterns, and as the delay increases, the patterns gradually become unstable. This study highlights the impact of the fear response delay on the stability and pattern formation in predator-prey systems, providing theoretical insights into the complexity of population dynamics.
本文研究了一个包含恐惧效应、猎物避难、Crowley-Martin型功能反应和交叉扩散的延迟捕食者-猎物模型。首先,我们分析了非时滞模型正平衡点的存在性和稳定性。然后,我们研究了延迟模型中出现图灵不稳定性的条件。利用多尺度摄动法推导了振幅方程,揭示了模式选择与系统参数之间的关系。同时,通过数值模拟验证了理论分析的准确性。结果表明,不同的控制参数可以诱导出不同的图案,包括斑点、条纹和混合图案。此外,我们发现恐惧反应延迟会影响模式的稳定时间,并且随着延迟的增加,模式逐渐变得不稳定。本研究强调了恐惧反应延迟对捕食者-猎物系统稳定性和模式形成的影响,为种群动态的复杂性提供了理论见解。
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引用次数: 0
A predator-prey model with poison dependent diffusion 具有毒素依赖扩散的捕食者-猎物模型
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-12 DOI: 10.1016/j.nonrwa.2025.104575
Xinyu Bo, Qi An, Wenjun Liu, Guangying Lv
Considering the increasing level of international environmental pollution, especially the discharge of nuclear effluents into the oceans, we consider in this paper, the dynamics of a predator-prey model in toxic environments. The concentration of toxins is no longer constant, but is influenced by time and location, and it will interact with predator-prey systems, thereby affecting the dynamic behavior of the entire ecosystem. The boundedness and positive definiteness of the model are obtained by using the comparison principle and the maximum principle. Afterwards, the threshold condition of toxicant concentration for the stability of the steady state solutions and the rate of convergence of the solutions are obtained by using the matrix positive definiteness, Schauder’s theorem and LaSalle’s invariance principle. Finally, numerical examples verify our results.
考虑到国际环境污染水平的不断增加,特别是向海洋排放核废料,本文考虑了有毒环境中捕食者-猎物模型的动力学。毒素的浓度不再是恒定的,而是受到时间和地点的影响,并会与捕食者-猎物系统相互作用,从而影响整个生态系统的动态行为。利用比较原理和极大值原理,得到了模型的有界性和正确定性。然后,利用矩阵正定性、Schauder定理和LaSalle不变性原理,得到了稳态解稳定的毒物浓度阈值条件和解的收敛速度。最后,通过数值算例验证了结果。
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引用次数: 0
Subsonic Euler flows with gravity in a two-dimensional finitely long curved nozzle 亚音速欧拉在二维有限长弯曲喷管中重力流动
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-11 DOI: 10.1016/j.nonrwa.2025.104566
Zihao Zhang
This paper concerns subsonic Euler flows in a two-dimensional finitely long slightly curved nozzle under the vertical gravity. Concerning the effect of the vertical gravity, we first establish the existence of subsonic shear flows in the flat nozzle. We then investigate the structural stability of these background subsonic flows under small perturbations of suitable boundary conditions on the entrance and exit and the upper and lower nozzle walls. It can be formulated as a nonlinear boundary value problem for a hyperbolic-elliptic mixed system. The main difficulty is that all the physical quantities are coupled with each other due to the existence of the vertical gravity. The approach is based on the Lagrangian transformation to straighten the streamline and the deformation-curl decomposition to deal with the hyperbolic and elliptic modes in the subsonic region. The key ingredient of the analysis is to solve the associated linearized elliptic boundary value problem with mixed boundary conditions in a weighted Hölder space.
本文研究了垂直重力作用下二维有限长微弯曲喷管中的亚音速欧拉流动。针对垂直重力的影响,首先建立了平面喷管内存在亚音速剪切流。然后,我们研究了这些背景亚音速流动在入口和出口以及上下喷嘴壁上适当边界条件的小扰动下的结构稳定性。它可以表述为一个双曲-椭圆混合系统的非线性边值问题。主要的困难是由于垂直重力的存在,所有的物理量都是相互耦合的。该方法基于拉格朗日变换对流线进行拉直,基于变形旋度分解对亚音速区域的双曲型和椭圆型进行处理。该分析的关键是在加权Hölder空间中求解具有混合边界条件的线性化椭圆边值问题。
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引用次数: 0
Local boundedness for minimizers of some non-uniformly polyconvex integrals 一些非一致多凸积分的极小值的局部有界性
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-11 DOI: 10.1016/j.nonrwa.2025.104564
Aiping Zhang, Zesheng Feng, Hongya Gao
This paper deals with a class of non-uniformly polyconvex integral functionals with splitting form in 3-dimensional Euclidean space. Under some structural conditions on the energy density, we prove that each component uα of local minimizer u is locally bounded. Our approach is based on a suitable adaptation of the celebrated De Giorgi’s iterative method, and it relies on an appropriate Caccioppoli-type inequality. Our result can be applied to the polyconvex integralΩ{α=13[λ(x)|Duα|p+|(adj2Du)α|q]+|detDu|r+α=13b(x)|uα|s}dxwith suitable functions λ(x) > 0, b(x) ≥ 0 and exponents p, q > 1, r, s ≥ 1.
研究了三维欧几里德空间中一类具有分裂形式的非一致多凸积分泛函。在能量密度的某些结构条件下,证明了局部极小器u的各分量uα是局部有界的。我们的方法是基于著名的De Giorgi的迭代方法的适当改编,它依赖于一个适当的caccioppolii型不等式。我们的结果可以应用于polyconvex积分∫Ω{∑α= 13(λ(x) | Duα| p + | (adj2Du)α| q] + | detDu | r +∑α= 13 b (x) | uα|年代}dxwith合适功能λ(x) 祝辞 0 b (x) ≥ 0和指数p, q 祝辞 1,r, s ≥ 1。
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引用次数: 0
Stability of force-free fields in weak ideal limits of Leray–Hopf solutions I: Linear force-free fields Leray-Hopf解弱理想极限下无力场的稳定性I:线性无力场
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-10 DOI: 10.1016/j.nonrwa.2025.104576
Ken Abe
We consider the stability of magnetohydrostatic (MHS) equilibria in the ideal MHD equations in a bounded and simply connected domain ΩR3. We show that the set of magnetic energy minimizers with constant helicity (i.e., linear force-free fields) is Lyapunov stable among the weak ideal limits of Leray–Hopf solutions to the viscous and resistive MHD equations.
我们考虑理想磁流体静力平衡(MHS)在有界单连通域Ω∧R3中的稳定性。我们证明了具有恒定螺旋度(即线性无力场)的磁能极小集在粘性和阻力MHD方程的Leray-Hopf解的弱理想极限内是Lyapunov稳定的。
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引用次数: 0
Adaptive Cucker-Smale networks: Limiting Laplacian time-varying dynamics 自适应cucker - small网络:限制拉普拉斯时变动力学
IF 1.8 3区 数学 Q1 MATHEMATICS, APPLIED Pub Date : 2025-12-10 DOI: 10.1016/j.nonrwa.2025.104563
Christian Kuehn , Jaeyoung Yoon
Differences in opinion can be seen as distances between individuals, and such differences do not always vanish over time. In this paper, we propose a modeling framework that captures the formation of opinion clusters, based on extensions of the Cucker-Smale and Hegselmann-Krause models to a combined adaptive (or co-evolutionary) network. Reducing our model to a singular limit of fast adaptation, we mathematically analyze the asymptotic behavior of the resulting Laplacian dynamics over various classes of temporal graphs and use these results to explain the behavior of the original proposed adaptive model for fast adaptation. In particular, our approach provides a general methodology for analyzing linear consensus models over time-varying networks that naturally arise as singular limits in many adaptive network models.
意见的差异可以被看作是个体之间的距离,而这种差异并不总是随着时间的推移而消失。在本文中,我们提出了一个基于Cucker-Smale和Hegselmann-Krause模型扩展到一个组合自适应(或共同进化)网络的建模框架,该框架可以捕获意见聚类的形成。将我们的模型简化为快速适应的奇异极限,我们从数学上分析了在各种类型的时间图上得到的拉普拉斯动力学的渐近行为,并使用这些结果来解释最初提出的快速适应模型的行为。特别是,我们的方法提供了一种通用的方法来分析时变网络上的线性共识模型,这些模型在许多自适应网络模型中自然出现为奇异极限。
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引用次数: 0
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Nonlinear Analysis-Real World Applications
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