Legal Medicine最新文献

Accurate estimation of shooting distance is one of the main aspects in forensic gunshot case reconstruction. Reliable methods to estimate shooting distance are thus important for forensic practitioners. In this pilot study we test how computed tomography (CT) based evaluation of bullet cavitation could potentially be utilized to differentiate shooting distance. To conduct our study, we utilized ballistic gelatine blocks as a soft tissue simulant. Test shooting was performed from two distances, 20 and 100 m. Four expanding monolithic bullets were used all in 0.30 caliber (Barnes TTSX, Sako Blade, Norma Ecostrike, Lapua Naturalis). The gelatine blocks were CT-scanned after the experiment. The scans were processed and segmented using an open-source 3D Slicer software to provide a 3D reconstruction of the cavitation and obtain numerical cavitation parameters (total volume and surface area of cavitation; maximum crack diameter; location of maximum cavitation). Our results indicated that all four bullets had distinct terminal ballistic performance. This could be detected from the bullet parameters such as maximum diameter and also from the pattern of cavitation. Shooting distance had a consistent, measurable association with bullet diameter and surface area of the gelatine cavity in all four bullets. Our preliminary pilot study underscores the potential of CT in the comprehensive analysis of gelatine cavitation in terminal ballistics. Our results suggest that it would be essential to know exact bullet type when shooting distance is estimated from terminal ballistic findings.

Falls are major causes of trauma in older people, often resulting in cervical spine/cord injury, and may even be fatal. We aimed to identify factors associated with cervical spine/cord injury and severe injury caused by falls to aid forensic evaluation. We retrospectively analyzed data for 83 individuals who fell between 2011 and 2023 at Shiga University of Medical Science. The characteristics of the victim, cause of death, presence of cervical spine/cord injury, injury severity, part of the body making contact with the impact surface, properties of the impact surface, and fall height were evaluated. Injury severity was assessed using the Abbreviated Injury Severity score and Injury Severity Score (ISS). Severe injury with ISS ≥ 16 occurred in 39.8% of victims and cervical spine/cord injury in 21.7%. Logistic regression analyses revealed that body mass (odds ratio [OR] 1.063, 95% confidence interval [CI] 1.003-1.126) and the part of the body making contact with the impact surface (chest/abdomen vs. head/face, OR 0.074, CI 0.007-0.723) significantly influenced the incidence of cervical spine/cord injury, and fall height >3 m was significantly associated with severe injury (OR 11.473, CI 2.163-60.868). These findings demonstrate that the severity of injury depends on the fall height, whereas cervical spine/cord injury is influenced by body mass and the part of the body making contact with the impact surface. Therefore, the collection of scene information, including the fall height, and body mass and posture are critical for postmortem examinations. Autopsy should be considered when cervical spine/cord injury is suspected.

Thoracic aortic dissection (TAD) is a life-threatening emergency frequently linked to underlying genetic variants, particularly in familial cases. Molecular autopsy has become increasingly valuable in forensic practice for identifying occult heritable disorders when routine autopsy alone cannot fully clarify the cause of death. Here, we report a 17-year-old male who died suddenly due to pericardial tamponade caused by ruptured TAD. Gene testing identified a novel ACTA2 variant, c.155_162delinsGCACA. This indel leads to two amino acid substitutions (p.K52_D53delinsST) and a deletion (p.S54del), involving evolutionarily conserved residues. Histological examination showed aortic medial degeneration, characterized by elastic fiber rupture and disorganized arrangement of smooth muscle cells. Family screening confirmed the variant was inherited from his mother, with his elder sister also carrying it; both the mother and sister exhibited abnormal aortic calcification and congenital heart disease. Our systematic review revealed that pathogenic ACTA2 variants frequently involve multiple organ systems. This multisystem pattern enhances the forensic value of genetic testing by providing additional phenotypic clues that help determine the underlying cause of sudden death when routine autopsy findings are insufficient. By identifying this novel variant, our study expands the ACTA2 variants spectrum relevant to forensic molecular autopsy and reinforces the importance of incorporating postmortem genetic testing into death investigations, particularly in unexplained fatal aortic events.