Pub Date : 2025-01-01Epub Date: 2025-01-15DOI: 10.1177/08953996241289267
Yinghui Zhang, Xing Zhao, Ke Chen, Hongwei Li
Background: Nonuniform sampling is a useful technique to optimize the acquisition of projections with a limited budget. Existing methods for selecting important projection views have limitations, such as relying on blueprint images or excessive computing resources.
Methods: We aim to develop a simple nonuniform sampling method for selecting informative projection views suitable for practical CT applications. The proposed algorithm is inspired by two key observations: projection errors contain angle-specific information, and adding views around error peaks effectively reduces errors and improves reconstruction. Given a budget and an initial view set, the proposed method involves: estimating projection errors based on current set of projection views, adding more projection views based on error equidistribution to smooth out errors, and final image reconstruction based on the new set of projection views. This process can be recursive, and the initial view can be obtained uniformly or from a prior for greater efficiency.
Results: Comparison with popular view selection algorithms using simulated and real data demonstrates consistently superior performance in identifying optimal views and generating high-quality reconstructions. Notably, the new algorithm performs well in both PSNR and SSIM metrics while being computationally efficient, enhancing its practicality for CT optimization.
Conclusions: A projection view selection algorithm based on error equidistribution is proposed, offering superior reconstruction quality and efficiency over existing methods. It is ready for real CT applications to optimize dose utilization.
{"title":"Selecting projection views based on error equidistribution for computed tomography.","authors":"Yinghui Zhang, Xing Zhao, Ke Chen, Hongwei Li","doi":"10.1177/08953996241289267","DOIUrl":"10.1177/08953996241289267","url":null,"abstract":"<p><strong>Background: </strong>Nonuniform sampling is a useful technique to optimize the acquisition of projections with a limited budget. Existing methods for selecting important projection views have limitations, such as relying on blueprint images or excessive computing resources.</p><p><strong>Methods: </strong>We aim to develop a simple nonuniform sampling method for selecting informative projection views suitable for practical CT applications. The proposed algorithm is inspired by two key observations: projection errors contain angle-specific information, and adding views around error peaks effectively reduces errors and improves reconstruction. Given a budget and an initial view set, the proposed method involves: estimating projection errors based on current set of projection views, adding more projection views based on error equidistribution to smooth out errors, and final image reconstruction based on the new set of projection views. This process can be recursive, and the initial view can be obtained uniformly or from a prior for greater efficiency.</p><p><strong>Results: </strong>Comparison with popular view selection algorithms using simulated and real data demonstrates consistently superior performance in identifying optimal views and generating high-quality reconstructions. Notably, the new algorithm performs well in both PSNR and SSIM metrics while being computationally efficient, enhancing its practicality for CT optimization.</p><p><strong>Conclusions: </strong>A projection view selection algorithm based on error equidistribution is proposed, offering superior reconstruction quality and efficiency over existing methods. It is ready for real CT applications to optimize dose utilization.</p>","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"249-269"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Ramesh Babu Durai,R Sathesh Raaj,Sindhu Chandra Sekharan,V S Nishok
BACKGROUNDContent-based image retrieval (CBIR) systems are vital for managing the large volumes of data produced by medical imaging technologies. They enable efficient retrieval of relevant medical images from extensive databases, supporting clinical diagnosis, treatment planning, and medical research.OBJECTIVEThis study aims to enhance CBIR systems' effectiveness in medical image analysis by introducing the VisualSift Ensembling Integration with Attention Mechanisms (VEIAM). VEIAM seeks to improve diagnostic accuracy and retrieval efficiency by integrating robust feature extraction with dynamic attention mechanisms.METHODSVEIAM combines Scale-Invariant Feature Transform (SIFT) with selective attention mechanisms to emphasize crucial regions within medical images dynamically. Implemented in Python, the model integrates seamlessly into existing medical image analysis workflows, providing a robust and accessible tool for clinicians and researchers.RESULTSThe proposed VEIAM model demonstrated an impressive accuracy of 97.34% in classifying and retrieving medical images. This performance indicates VEIAM's capability to discern subtle patterns and textures critical for accurate diagnostics.CONCLUSIONSBy merging SIFT-based feature extraction with attention processes, VEIAM offers a discriminatively powerful approach to medical image analysis. Its high accuracy and efficiency in retrieving relevant medical images make it a promising tool for enhancing diagnostic processes and supporting medical research in CBIR systems.
{"title":"A comprehensive guide to content-based image retrieval algorithms with visualsift ensembling.","authors":"C Ramesh Babu Durai,R Sathesh Raaj,Sindhu Chandra Sekharan,V S Nishok","doi":"10.3233/xst-240189","DOIUrl":"https://doi.org/10.3233/xst-240189","url":null,"abstract":"BACKGROUNDContent-based image retrieval (CBIR) systems are vital for managing the large volumes of data produced by medical imaging technologies. They enable efficient retrieval of relevant medical images from extensive databases, supporting clinical diagnosis, treatment planning, and medical research.OBJECTIVEThis study aims to enhance CBIR systems' effectiveness in medical image analysis by introducing the VisualSift Ensembling Integration with Attention Mechanisms (VEIAM). VEIAM seeks to improve diagnostic accuracy and retrieval efficiency by integrating robust feature extraction with dynamic attention mechanisms.METHODSVEIAM combines Scale-Invariant Feature Transform (SIFT) with selective attention mechanisms to emphasize crucial regions within medical images dynamically. Implemented in Python, the model integrates seamlessly into existing medical image analysis workflows, providing a robust and accessible tool for clinicians and researchers.RESULTSThe proposed VEIAM model demonstrated an impressive accuracy of 97.34% in classifying and retrieving medical images. This performance indicates VEIAM's capability to discern subtle patterns and textures critical for accurate diagnostics.CONCLUSIONSBy merging SIFT-based feature extraction with attention processes, VEIAM offers a discriminatively powerful approach to medical image analysis. Its high accuracy and efficiency in retrieving relevant medical images make it a promising tool for enhancing diagnostic processes and supporting medical research in CBIR systems.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"79 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142258308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Moock, Darien E. Arce Chávez, Crescencio García-Segundo, L. Ruiz-Huerta
BACKGROUND: The environmental impact on industrial X-ray tomography systems has gained its attention in terms of image precision and metrology over recent years, yet is still complex due to the variety of applications. OBJECTIVE: The current study explores the photothermal repercussions of the overall radiation exposure time. It shows the emerging dimensional uncertainty when measuring a stainless steel sphere by means of circular tomography scans. METHODS: The authors develop a novel frame difference method for X-ray radiographies to evaluate the spatial changes induced in the projected absorption maps on the X-ray panel. The object of interest has a simple geometry for the purpose of proof of concept. The dominant source of the observed radial uncertainty is the photothermal effect due to high-energy X-ray scattering at the metal workpiece. Thermal variations are monitored by an infrared camera within the industrial tomography system, which confines that heat in the industrial grade X-ray system. RESULTS: The authors demonstrate that dense industrial computed tomography programs with major X-ray power notably affect the uncertainty of digital dimensional measurements. The registered temperature variations are consistent with dimensional changes in radiographies and hence form a source of error that might result in visible artifacts within the 3D image reconstruction. CONCLUSIONS: This contribution is of fundamental value to reach the balance between the number of projections and radial uncertainty tolerance when performing analysis with X-ray dimensional exploration in precision measurements with industrial tomography.
背景:近年来,工业 X 射线层析成像系统对环境的影响在图像精度和计量方面越来越受到关注,但由于应用的多样性,这种影响仍然很复杂。目的:本研究探讨了整体辐射照射时间的光热影响。它显示了通过圆形断层扫描测量不锈钢球时出现的尺寸不确定性。方法:作者为 X 射线放射成像开发了一种新颖的帧差法,用于评估 X 射线面板上的投射吸收图引起的空间变化。为了验证概念,研究对象的几何形状非常简单。观察到的径向不确定性的主要来源是金属工件上高能 X 射线散射引起的光热效应。热变化由工业层析成像系统中的红外摄像机监测,红外摄像机将热量限制在工业级 X 射线系统中。结果:作者证明,具有强大 X 射线能量的密集型工业计算机断层扫描程序会明显影响数字尺寸测量的不确定性。记录的温度变化与射线照片中的尺寸变化一致,因此形成了一个误差源,可能导致三维图像重建中出现可见的伪影。结论:在使用工业断层扫描技术进行精密测量时,利用 X 射线尺寸探测进行分析时,要在投影次数和径向不确定性容差之间取得平衡,本研究成果具有重要价值。
{"title":"Photothermal effect in X-ray images for computed tomography of metallic parts: Stainless steel spheres","authors":"V. Moock, Darien E. Arce Chávez, Crescencio García-Segundo, L. Ruiz-Huerta","doi":"10.3233/xst-230260","DOIUrl":"https://doi.org/10.3233/xst-230260","url":null,"abstract":"BACKGROUND: The environmental impact on industrial X-ray tomography systems has gained its attention in terms of image precision and metrology over recent years, yet is still complex due to the variety of applications. OBJECTIVE: The current study explores the photothermal repercussions of the overall radiation exposure time. It shows the emerging dimensional uncertainty when measuring a stainless steel sphere by means of circular tomography scans. METHODS: The authors develop a novel frame difference method for X-ray radiographies to evaluate the spatial changes induced in the projected absorption maps on the X-ray panel. The object of interest has a simple geometry for the purpose of proof of concept. The dominant source of the observed radial uncertainty is the photothermal effect due to high-energy X-ray scattering at the metal workpiece. Thermal variations are monitored by an infrared camera within the industrial tomography system, which confines that heat in the industrial grade X-ray system. RESULTS: The authors demonstrate that dense industrial computed tomography programs with major X-ray power notably affect the uncertainty of digital dimensional measurements. The registered temperature variations are consistent with dimensional changes in radiographies and hence form a source of error that might result in visible artifacts within the 3D image reconstruction. CONCLUSIONS: This contribution is of fundamental value to reach the balance between the number of projections and radial uncertainty tolerance when performing analysis with X-ray dimensional exploration in precision measurements with industrial tomography.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"43 36","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139442549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetic retinopathy (DR) is one of the leading causes of blindness. However, because the data distribution of classes is not always balanced, it is challenging for automated early DR detection using deep learning techniques. In this paper, we propose an adaptive weighted ensemble learning method for DR detection based on optical coherence tomography (OCT) images. Specifically, we develop an ensemble learning model based on three advanced deep learning models for higher performance. To better utilize the cues implied in these base models, a novel decision fusion scheme is proposed based on the Bayesian theory in terms of the key evaluation indicators, to dynamically adjust the weighting distribution of base models to alleviate the negative effects potentially caused by the problem of unbalanced data size. Extensive experiments are performed on two public datasets to verify the effectiveness of the proposed method. A quadratic weighted kappa of 0.8487 and an accuracy of 0.9343 on the DRAC2022 dataset, and a quadratic weighted kappa of 0.9007 and an accuracy of 0.8956 on the APTOS2019 dataset are obtained, respectively. The results demonstrate that our method has the ability to enhance the ovearall performance of DR detection on OCT images.
糖尿病视网膜病变(DR)是导致失明的主要原因之一。然而,由于类的数据分布并不总是平衡的,因此使用深度学习技术自动进行早期 DR 检测具有挑战性。在本文中,我们提出了一种基于光学相干断层扫描(OCT)图像的自适应加权集合学习方法,用于 DR 检测。具体来说,我们开发了一种基于三种高级深度学习模型的集合学习模型,以获得更高的性能。为了更好地利用这些基础模型中隐含的线索,我们提出了一种基于贝叶斯理论的关键评价指标的新型决策融合方案,以动态调整基础模型的权重分布,从而减轻数据量不平衡问题可能带来的负面影响。为了验证所提方法的有效性,我们在两个公共数据集上进行了大量实验。在 DRAC2022 数据集上得到的二次加权 kappa 分别为 0.8487 和 0.9343,在 APTOS2019 数据集上得到的二次加权 kappa 分别为 0.9007 和 0.8956。这些结果表明,我们的方法有能力提高 OCT 图像 DR 检测的总体性能。
{"title":"An adaptive weighted ensemble learning network for diabetic retinopathy classification","authors":"Panpan Wu, Yue Qu, Ziping Zhao, Yue Cui, Yurou Xu, Peng An, Hengyong Yu","doi":"10.3233/xst-230252","DOIUrl":"https://doi.org/10.3233/xst-230252","url":null,"abstract":"Diabetic retinopathy (DR) is one of the leading causes of blindness. However, because the data distribution of classes is not always balanced, it is challenging for automated early DR detection using deep learning techniques. In this paper, we propose an adaptive weighted ensemble learning method for DR detection based on optical coherence tomography (OCT) images. Specifically, we develop an ensemble learning model based on three advanced deep learning models for higher performance. To better utilize the cues implied in these base models, a novel decision fusion scheme is proposed based on the Bayesian theory in terms of the key evaluation indicators, to dynamically adjust the weighting distribution of base models to alleviate the negative effects potentially caused by the problem of unbalanced data size. Extensive experiments are performed on two public datasets to verify the effectiveness of the proposed method. A quadratic weighted kappa of 0.8487 and an accuracy of 0.9343 on the DRAC2022 dataset, and a quadratic weighted kappa of 0.9007 and an accuracy of 0.8956 on the APTOS2019 dataset are obtained, respectively. The results demonstrate that our method has the ability to enhance the ovearall performance of DR detection on OCT images.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"58 7","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bo Liu, Shaima Haithem Zaki, Eduardo García, Amanda Bonilla, D. Thabit, Aya Hussein Adab
OBJECTIVE: It seems that dose rate (DR) and photon beam energy (PBE) may influence the sensitivity and response of polymer gel dosimeters. In the current project, the sensitivity and response dependence of optimized PASSAG gel dosimeter (OPGD) on DR and PBE were assessed. MATERIALS AND METHODS: We fabricated the OPGD and the gel samples were irradiated with various DRs and PBEs. Then, the sensitivity and response (R 2) of OPGD were obtained by MRI at various doses and post-irradiation times. RESULTS: Our analysis showed that the sensitivity and response of OPGD are not affected by the evaluated DRs and PBEs. It was also found that the dose resolution values of OPGD ranged from 9 to 33 cGy and 12 to 34 cGy for the evaluated DRs and PBEs, respectively. Additionally, the data demonstrated that the sensitivity and response dependence of OPGD on DR and PBE do not vary over various times after the irradiation. CONCLUSIONS: The findings of this research project revealed that the sensitivity and response dependence of OPGD are independent of DR and PBE.
目的:剂量率(DR)和光子束能量(PBE)似乎会影响聚合物凝胶剂量计的灵敏度和响应。在本项目中,我们评估了优化 PASSAG 凝胶剂量计(OPGD)的灵敏度和响应与剂量率和光子束能量的关系。材料与方法:我们制作了 OPGD,并用不同的 DR 和 PBE 对凝胶样品进行了辐照。然后,在不同剂量和辐照后时间内,通过核磁共振成像获得 OPGD 的灵敏度和响应(R 2)。结果:我们的分析表明,OPGD 的灵敏度和反应不受所评估的 DR 和 PBE 的影响。我们还发现,对于所评估的 DR 和 PBE,OPGD 的剂量分辨率值分别为 9 至 33 cGy 和 12 至 34 cGy。此外,数据还表明,OPGD 对 DR 和 PBE 的敏感性和反应依赖性在照射后的不同时间内没有变化。结论:本研究项目的结果表明,OPGD 的灵敏度和反应依赖性与 DR 和 PBE 无关。
{"title":"The investigation of dose rate and photon beam energy dependence of optimized PASSAG polymer gel dosimeter using magnetic resonance imaging","authors":"Bo Liu, Shaima Haithem Zaki, Eduardo García, Amanda Bonilla, D. Thabit, Aya Hussein Adab","doi":"10.3233/xst-230282","DOIUrl":"https://doi.org/10.3233/xst-230282","url":null,"abstract":"OBJECTIVE: It seems that dose rate (DR) and photon beam energy (PBE) may influence the sensitivity and response of polymer gel dosimeters. In the current project, the sensitivity and response dependence of optimized PASSAG gel dosimeter (OPGD) on DR and PBE were assessed. MATERIALS AND METHODS: We fabricated the OPGD and the gel samples were irradiated with various DRs and PBEs. Then, the sensitivity and response (R 2) of OPGD were obtained by MRI at various doses and post-irradiation times. RESULTS: Our analysis showed that the sensitivity and response of OPGD are not affected by the evaluated DRs and PBEs. It was also found that the dose resolution values of OPGD ranged from 9 to 33 cGy and 12 to 34 cGy for the evaluated DRs and PBEs, respectively. Additionally, the data demonstrated that the sensitivity and response dependence of OPGD on DR and PBE do not vary over various times after the irradiation. CONCLUSIONS: The findings of this research project revealed that the sensitivity and response dependence of OPGD are independent of DR and PBE.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"56 20","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shi Bo Jiang, Yue Wen Sun, Shuo Xu, Hua Xia Zhang, Zhi Fang Wu
Accurate segmentation of industrial CT images is of great significance in industrial fields such as quality inspection and defect analysis. However, reconstruction of industrial CT images often suffers from typical metal artifacts caused by factors like beam hardening, scattering, statistical noise, and partial volume effects. Traditional segmentation methods are difficult to achieve precise segmentation of CT images mainly due to the presence of these metal artifacts. Furthermore, acquiring paired CT image data required by fully supervised networks proves to be extremely challenging. To address these issues, this paper introduces an improved CycleGAN approach for achieving semi-supervised segmentation of industrial CT images. This method not only eliminates the need for removing metal artifacts and noise, but also enables the direct conversion of metal artifact-contaminated images into segmented images without the requirement of paired data. The average values of quantitative assessment of image segmentation performance can reach 0.96645 for Dice Similarity Coefficient(Dice) and 0.93718 for Intersection over Union(IoU). In comparison to traditional segmentation methods, it presents significant improvements in both quantitative metrics and visual quality, provides valuable insights for further research.
{"title":"Semi-supervised segmentation of metal-artifact contaminated industrial CT images using improved CycleGAN","authors":"Shi Bo Jiang, Yue Wen Sun, Shuo Xu, Hua Xia Zhang, Zhi Fang Wu","doi":"10.3233/xst-230233","DOIUrl":"https://doi.org/10.3233/xst-230233","url":null,"abstract":"Accurate segmentation of industrial CT images is of great significance in industrial fields such as quality inspection and defect analysis. However, reconstruction of industrial CT images often suffers from typical metal artifacts caused by factors like beam hardening, scattering, statistical noise, and partial volume effects. Traditional segmentation methods are difficult to achieve precise segmentation of CT images mainly due to the presence of these metal artifacts. Furthermore, acquiring paired CT image data required by fully supervised networks proves to be extremely challenging. To address these issues, this paper introduces an improved CycleGAN approach for achieving semi-supervised segmentation of industrial CT images. This method not only eliminates the need for removing metal artifacts and noise, but also enables the direct conversion of metal artifact-contaminated images into segmented images without the requirement of paired data. The average values of quantitative assessment of image segmentation performance can reach 0.96645 for Dice Similarity Coefficient(Dice) and 0.93718 for Intersection over Union(IoU). In comparison to traditional segmentation methods, it presents significant improvements in both quantitative metrics and visual quality, provides valuable insights for further research.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"53 12","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Sayed Tanveer, Christopher Wiedeman, Mengzhou Li, Yongyi Shi, Bruno De Man, Jonathan S. Maltz, Ge Wang
BACKGROUND: In recent years, deep reinforcement learning (RL) has been applied to various medical tasks and produced encouraging results. OBJECTIVE: In this paper, we demonstrate the feasibility of deep RL for denoising simulated deep-silicon photon-counting CT (PCCT) data in both full and interior scan modes. PCCT offers higher spatial and spectral resolution than conventional CT, requiring advanced denoising methods to suppress noise increase. METHODS: In this work, we apply a dueling double deep Q network (DDDQN) to denoise PCCT data for maximum contrast-to-noise ratio (CNR) and a multi-agent approach to handle data non-stationarity. RESULTS: Using our method, we obtained significant image quality improvement for single-channel scans and consistent improvement for all three channels of multichannel scans. For the single-channel interior scans, the PSNR (dB) and SSIM increased from 33.4078 and 0.9165 to 37.4167 and 0.9790 respectively. For the multichannel interior scans, the channel-wise PSNR (dB) increased from 31.2348, 30.7114, and 30.4667 to 31.6182, 30.9783, and 30.8427 respectively. Similarly, the SSIM improved from 0.9415, 0.9445, and 0.9336 to 0.9504, 0.9493, and 0.0326 respectively. CONCLUSIONS: Our results show that the RL approach improves image quality effectively, efficiently, and consistently across multiple spectral channels and has great potential in clinical applications.
{"title":"Deep-silicon photon-counting x-ray projection denoising through reinforcement learning","authors":"Md Sayed Tanveer, Christopher Wiedeman, Mengzhou Li, Yongyi Shi, Bruno De Man, Jonathan S. Maltz, Ge Wang","doi":"10.3233/xst-230278","DOIUrl":"https://doi.org/10.3233/xst-230278","url":null,"abstract":"BACKGROUND: In recent years, deep reinforcement learning (RL) has been applied to various medical tasks and produced encouraging results. OBJECTIVE: In this paper, we demonstrate the feasibility of deep RL for denoising simulated deep-silicon photon-counting CT (PCCT) data in both full and interior scan modes. PCCT offers higher spatial and spectral resolution than conventional CT, requiring advanced denoising methods to suppress noise increase. METHODS: In this work, we apply a dueling double deep Q network (DDDQN) to denoise PCCT data for maximum contrast-to-noise ratio (CNR) and a multi-agent approach to handle data non-stationarity. RESULTS: Using our method, we obtained significant image quality improvement for single-channel scans and consistent improvement for all three channels of multichannel scans. For the single-channel interior scans, the PSNR (dB) and SSIM increased from 33.4078 and 0.9165 to 37.4167 and 0.9790 respectively. For the multichannel interior scans, the channel-wise PSNR (dB) increased from 31.2348, 30.7114, and 30.4667 to 31.6182, 30.9783, and 30.8427 respectively. Similarly, the SSIM improved from 0.9415, 0.9445, and 0.9336 to 0.9504, 0.9493, and 0.0326 respectively. CONCLUSIONS: Our results show that the RL approach improves image quality effectively, efficiently, and consistently across multiple spectral channels and has great potential in clinical applications.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"61 48","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dehua Wang, Hayder Jasim Taher, Murtadha Al-Fatlawi, Badr Ahmed Abdullah, Munojat Khayatovna Ismailova, R. Abedi-Firouzjah
AIM: This study assessed the myocardial infarction (MI) using a novel fusion approach (multi-flavored or tensor-based) of multi-parametric cardiac magnetic resonance imaging (CMRI) at four sequences; T1-weighted (T1W) in the axial plane, sense-balanced turbo field echo (sBTFE) in the axial plane, late gadolinium enhancement of heart short axis (LGE-SA) in the sagittal plane, and four-chamber views of LGE (LGE-4CH) in the axial plane. METHODS: After considering the inclusion and exclusion criteria, 115 patients (83 with MI diagnosis and 32 as healthy control patients), were included in the present study. Radiomic features were extracted from the whole left ventricular myocardium (LVM). Feature selection methods were Least Absolute Shrinkage and Selection Operator (Lasso), Minimum Redundancy Maximum Relevance (MRMR), Chi-Square (Chi2), Analysis of Variance (Anova), Recursive Feature Elimination (RFE), and SelectPersentile. The classification methods were Support Vector Machine (SVM), Logistic Regression (LR), and Random Forest (RF). Different metrics, including receiver operating characteristic curve (AUC), accuracy, F1- score, precision, sensitivity, and specificity were calculated for radiomic features extracted from CMR images using stratified five-fold cross-validation. RESULTS: For the MI detection, Lasso (as the feature selection) and RF/LR (as the classifiers) in sBTFE sequences had the best performance (AUC: 0.97). All features and classifiers of T1 + sBTFE sequences with the weighted method (as the fused image), had a good performance (AUC: 0.97). In addition, the results of the evaluated metrics, especially mean AUC and accuracy for all models, determined that the T1 + sBTFE-weighted fused method had strong predictive performance (AUC: 0.93±0.05; accuracy: 0.93±0.04), followed by T1 + sBTFE-PCA fused method (AUC: 0.85±0.06; accuracy: 0.84±0.06). CONCLUSION: Our selected CMRI sequences demonstrated that radiomics analysis enables to detection of MI accurately. Among the investigated sequences, the T1 + sBTFE-weighted fused method with the highest AUC and accuracy values was chosen as the best technique for MI detection.
{"title":"Multi-parametric assessment of cardiac magnetic resonance images to distinguish myocardial infarctions: A tensor-based radiomics feature","authors":"Dehua Wang, Hayder Jasim Taher, Murtadha Al-Fatlawi, Badr Ahmed Abdullah, Munojat Khayatovna Ismailova, R. Abedi-Firouzjah","doi":"10.3233/xst-230307","DOIUrl":"https://doi.org/10.3233/xst-230307","url":null,"abstract":"AIM: This study assessed the myocardial infarction (MI) using a novel fusion approach (multi-flavored or tensor-based) of multi-parametric cardiac magnetic resonance imaging (CMRI) at four sequences; T1-weighted (T1W) in the axial plane, sense-balanced turbo field echo (sBTFE) in the axial plane, late gadolinium enhancement of heart short axis (LGE-SA) in the sagittal plane, and four-chamber views of LGE (LGE-4CH) in the axial plane. METHODS: After considering the inclusion and exclusion criteria, 115 patients (83 with MI diagnosis and 32 as healthy control patients), were included in the present study. Radiomic features were extracted from the whole left ventricular myocardium (LVM). Feature selection methods were Least Absolute Shrinkage and Selection Operator (Lasso), Minimum Redundancy Maximum Relevance (MRMR), Chi-Square (Chi2), Analysis of Variance (Anova), Recursive Feature Elimination (RFE), and SelectPersentile. The classification methods were Support Vector Machine (SVM), Logistic Regression (LR), and Random Forest (RF). Different metrics, including receiver operating characteristic curve (AUC), accuracy, F1- score, precision, sensitivity, and specificity were calculated for radiomic features extracted from CMR images using stratified five-fold cross-validation. RESULTS: For the MI detection, Lasso (as the feature selection) and RF/LR (as the classifiers) in sBTFE sequences had the best performance (AUC: 0.97). All features and classifiers of T1 + sBTFE sequences with the weighted method (as the fused image), had a good performance (AUC: 0.97). In addition, the results of the evaluated metrics, especially mean AUC and accuracy for all models, determined that the T1 + sBTFE-weighted fused method had strong predictive performance (AUC: 0.93±0.05; accuracy: 0.93±0.04), followed by T1 + sBTFE-PCA fused method (AUC: 0.85±0.06; accuracy: 0.84±0.06). CONCLUSION: Our selected CMRI sequences demonstrated that radiomics analysis enables to detection of MI accurately. Among the investigated sequences, the T1 + sBTFE-weighted fused method with the highest AUC and accuracy values was chosen as the best technique for MI detection.","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":"56 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jarrod Cortez, Ignacio Romero, Jason Ngo, Md Sayed Tanveer Azam, Chuang Niu, Cássio Luiz Coutinho Almeida-da-Silva, Leticia Ferreira Cabido, David M Ojcius, Wei-Chun Chin, Ge Wang, Changqing Li
Background: Periodontal disease affects over 50% of the global population and is characterized by gingivitis as the initial sign. One dental health issue that may contribute to the development of periodontal disease is foreign body gingivitis (FBG), which can result from exposure to some kinds of foreign metal particles from dental products or food.
Objective: We design a novel, portable, affordable, multispectral X-ray and fluorescence optical microscopic imaging system dedicated to detecting and differentiating metal oxide particles in dental pathological tissues. A novel denoising algorithm is applied. We verify the feasibility and optimize the performance of the imaging system with numerical simulations.
Methods: The designed imaging system has a focused X-ray tube with tunable energy spectra and thin scintillator coupled with an optical microscope as detector. A simulated soft tissue phantom is embedded with 2-micron thick metal oxide discs as the imaged object. GATE software is used to optimize the systematic parameters such as energy bandwidth and X-ray photon number. We have also applied a novel denoising method, Noise2Sim with a two-layer UNet structure, to improve the simulated image quality.
Results: The use of an X-ray source operating with an energy bandwidth of 5 keV, X-ray photon number of 108, and an X-ray detector with a 0.5 micrometer pixel size in a 100 by 100-pixel array allowed for the detection of particles as small as 0.5 micrometer. With the Noise2Sim algorithm, the CNR has improved substantially. A typical example is that the Aluminum (Al) target's CNR is improved from 6.78 to 9.72 for the case of 108 X-ray photons with the Chromium (Cr) source of 5 keV bandwidth.
Conclusions: Different metal oxide particles were differentiated using Contrast-to-Noise ratio (CNR) by utilizing four different X-ray spectra.
{"title":"Multiple energy X-ray imaging of metal oxide particles inside gingival tissues.","authors":"Jarrod Cortez, Ignacio Romero, Jason Ngo, Md Sayed Tanveer Azam, Chuang Niu, Cássio Luiz Coutinho Almeida-da-Silva, Leticia Ferreira Cabido, David M Ojcius, Wei-Chun Chin, Ge Wang, Changqing Li","doi":"10.3233/XST-230175","DOIUrl":"10.3233/XST-230175","url":null,"abstract":"<p><strong>Background: </strong>Periodontal disease affects over 50% of the global population and is characterized by gingivitis as the initial sign. One dental health issue that may contribute to the development of periodontal disease is foreign body gingivitis (FBG), which can result from exposure to some kinds of foreign metal particles from dental products or food.</p><p><strong>Objective: </strong>We design a novel, portable, affordable, multispectral X-ray and fluorescence optical microscopic imaging system dedicated to detecting and differentiating metal oxide particles in dental pathological tissues. A novel denoising algorithm is applied. We verify the feasibility and optimize the performance of the imaging system with numerical simulations.</p><p><strong>Methods: </strong>The designed imaging system has a focused X-ray tube with tunable energy spectra and thin scintillator coupled with an optical microscope as detector. A simulated soft tissue phantom is embedded with 2-micron thick metal oxide discs as the imaged object. GATE software is used to optimize the systematic parameters such as energy bandwidth and X-ray photon number. We have also applied a novel denoising method, Noise2Sim with a two-layer UNet structure, to improve the simulated image quality.</p><p><strong>Results: </strong>The use of an X-ray source operating with an energy bandwidth of 5 keV, X-ray photon number of 108, and an X-ray detector with a 0.5 micrometer pixel size in a 100 by 100-pixel array allowed for the detection of particles as small as 0.5 micrometer. With the Noise2Sim algorithm, the CNR has improved substantially. A typical example is that the Aluminum (Al) target's CNR is improved from 6.78 to 9.72 for the case of 108 X-ray photons with the Chromium (Cr) source of 5 keV bandwidth.</p><p><strong>Conclusions: </strong>Different metal oxide particles were differentiated using Contrast-to-Noise ratio (CNR) by utilizing four different X-ray spectra.</p>","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"87-103"},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Thyroid tumor is considered to be a very rare form of cancer. But recent researches and surveys highlight the fact that it is becoming prevalent these days because of various factors.
Objectives: This paper proposes a novel hybrid classification system that is able to identify and classify the above said four different types of thyroid tumors using high end artificial intelligence techniques. The input data set is obtained from Digital Database of Thyroid Ultrasound Images through Kaggle repository and augmented for achieving a better classification performance using data warping mechanisms like flipping, rotation, cropping, scaling, and shifting.
Methods: The input data after augmentation goes through preprocessing with the help of bilateral filter and is contrast enhanced using dynamic histogram equalization. The ultrasound images are then segmented using SegNet algorithm of convolutional neural network. The features needed for thyroid tumor classification are obtained from two different algorithms called CapsuleNet and EfficientNetB2 and both the features are fused together. This process of feature fusion is carried out to heighten the accuracy of classification.
Results: A Multilayer Perceptron Classifier is used for classification and Bonobo optimizer is employed for optimizing the results produced. The classification performance of the proposed model is weighted using metrics like accuracy, sensitivity, specificity, F1-score, and Matthew's correlation coefficient.
Conclusion: It can be observed from the results that the proposed multilayer perceptron based thyroid tumor type classification system works in an efficient manner than the existing classifiers like CANFES, Spatial Fuzzy C means, Deep Belief Networks, Thynet and Generative adversarial network and Long Short-Term memory.
{"title":"A hybrid thyroid tumor type classification system using feature fusion, multilayer perceptron and bonobo optimization.","authors":"B Shankarlal, S Dhivya, K Rajesh, S Ashok","doi":"10.3233/XST-230430","DOIUrl":"10.3233/XST-230430","url":null,"abstract":"<p><strong>Background: </strong>Thyroid tumor is considered to be a very rare form of cancer. But recent researches and surveys highlight the fact that it is becoming prevalent these days because of various factors.</p><p><strong>Objectives: </strong>This paper proposes a novel hybrid classification system that is able to identify and classify the above said four different types of thyroid tumors using high end artificial intelligence techniques. The input data set is obtained from Digital Database of Thyroid Ultrasound Images through Kaggle repository and augmented for achieving a better classification performance using data warping mechanisms like flipping, rotation, cropping, scaling, and shifting.</p><p><strong>Methods: </strong>The input data after augmentation goes through preprocessing with the help of bilateral filter and is contrast enhanced using dynamic histogram equalization. The ultrasound images are then segmented using SegNet algorithm of convolutional neural network. The features needed for thyroid tumor classification are obtained from two different algorithms called CapsuleNet and EfficientNetB2 and both the features are fused together. This process of feature fusion is carried out to heighten the accuracy of classification.</p><p><strong>Results: </strong>A Multilayer Perceptron Classifier is used for classification and Bonobo optimizer is employed for optimizing the results produced. The classification performance of the proposed model is weighted using metrics like accuracy, sensitivity, specificity, F1-score, and Matthew's correlation coefficient.</p><p><strong>Conclusion: </strong>It can be observed from the results that the proposed multilayer perceptron based thyroid tumor type classification system works in an efficient manner than the existing classifiers like CANFES, Spatial Fuzzy C means, Deep Belief Networks, Thynet and Generative adversarial network and Long Short-Term memory.</p>","PeriodicalId":49948,"journal":{"name":"Journal of X-Ray Science and Technology","volume":" ","pages":"651-675"},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139941063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}