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Morphologic and Morphometric Evaluation of the Carotid Artery Wall: A Cadaver-Based Light and Scanning Electron Microscopic Study 颈动脉壁的形态学和形态计量学评价:基于尸体的光学和扫描电镜研究
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_168_21
Hilal Nakkaş, F. Çelikkan, N. Apaydın, O. Evirgen
Introduction: A variety of changes occur on the elastic artery wall with age. Ultrastructural studies made in this area are mostly animal based. We aimed to evaluate wall changes and three-dimensional organization of the elastic lamellae with aging in humans. Material and Methods: Common carotid arteries were obtained from 17 human cadavers which were grouped as G1 (n = 6), 30–39 years; G2 (n = 5), 40–49 years; and G3 (n = 6), >50 years of age. Samples were evaluated under light and scanning electron microscopes. Results: Examination of G1 revealed intimal thickening and foamy cell infiltration. G2 and G3 had plaques bulging into the lumen and interlamellar space was widened. The lamellae were more straight. There was a positive correlation between intimal thickness and age. Elastic fiber content decreased with aging. Scanning electron microscopic analysis confirmed the findings. G1 and G2 had a smooth surfaced internal elastic lamina with uniform fenestrations whereas G3 contained numerous irregular fenestrae. Discussion and Conclusion: With this study, we showed some other wall structure changes beside plaque formation by aging. Which layer is affected the most was not clear at previous clinical studies because using ultrasonography (USG) cannot address the layer. Microscopic evaluation of this study revealed that when a wall thickening is detected by USG, it is due to intimal thickening. The specific vessel layer structural changes are important for proper treatment.
随着年龄的增长,弹性动脉壁发生多种变化。在这一领域进行的超微结构研究大多是基于动物的。我们的目的是评估随年龄增长的人弹性板壁的变化和三维组织。材料与方法:取17具人尸体的颈总动脉,分为G1组(n = 6), 30 ~ 39岁;G2 (n = 5), 40-49岁;G3 (n = 6), >50岁。在光镜和扫描电镜下对样品进行评价。结果:G1检查示内膜增厚,泡沫细胞浸润。G2和G3有斑块向管腔内膨出,层间间隙增宽。薄片更直。内膜厚度与年龄呈正相关。弹性纤维含量随老化而降低。扫描电镜分析证实了这一发现。G1和G2具有表面光滑的内部弹性层,具有均匀的开孔,而G3具有大量不规则的开孔。讨论与结论:在这项研究中,我们发现除了斑块形成外,还有一些其他的壁结构变化。在以往的临床研究中,由于超声(USG)不能确定哪一层受影响最大,因此不清楚哪一层受影响最大。本研究的显微评价显示,当超声心动图检测到壁增厚时,这是由于内膜增厚。特定的血管层结构变化对于适当的治疗是重要的。
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引用次数: 0
Effect of different doses of aluminum chloride on neurodegeneration in hippocampus region of the rat brain 不同剂量氯化铝对大鼠脑海马区神经退行性变的影响
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_39_22
Amit Massand, Mallika Basera, Sonal Grace, Reshma Kumarachandra, K. Sudha, R. Rai, B. Murlimanju, K. Sowndarya
Introduction: Aluminum (AL) compounds are widely used as food additives, cosmetics, antacids, and buffered aspirins. Chronic consumption of AL may lead to its accumulation in tissues causing AL toxicity. The study aims to investigate the toxic effect of AlCl3 on hippocampus region of rat brain by qualitative and quantitative analysis of neurons. Material and Methods: Adult male albino Wistar rats were divided into three groups with six rats in each group. Group 1 was the control, Group 2 rats received 100 mg/kg b. w, and Group 3 received 300 mg/kg b. w of AlCl3 orally for 30 days. The neuronal count was done at the CA1, CA2, CA3, and CA4 regions of hippocampus by staining with cresyl violet stain. Neuronal damage in the AlCl3 groups was compared with the control group. Results: A significant damage was observed in all the regions of hippocampus both in Groups 2 and 3 compared to the control group (P < 0.00001). Further higher dose of AL caused marked neuronal damage in CA1 (P < 0.03) and CA3 (P < 0.05) regions compared to the lower dose of AL. The neurons in the CA3 and CA1 regions were most vulnerable to AL toxicity and the CA2 region of the hippocampus had a maximum number of viable neurons indicative of resistance to AL toxicosis. Discussion and Conclusion: Consumption of higher dose of AL even for a short term could have variable degrees of deleterious effects on different regions of the rat brain. This study sets a background for an in-depth exploration on toxicology of AL compounds on human participants which could be of public health importance.
铝(AL)化合物广泛用于食品添加剂、化妆品、抗酸剂和缓冲阿司匹林。慢性消耗AL可导致其在组织中积累,引起AL毒性。本研究旨在通过神经元的定性和定量分析,探讨AlCl3对大鼠脑海马区的毒性作用。材料与方法:将成年雄性白化Wistar大鼠分为3组,每组6只。1组为对照组,2组给予AlCl3 100 mg/kg b. w, 3组给予AlCl3 300 mg/kg b. w,连续30 d。用甲酚紫染色法对海马CA1、CA2、CA3、CA4区进行神经元计数。比较AlCl3组与对照组的神经元损伤情况。结果:与对照组相比,2、3组海马各区域均出现明显损伤(P < 0.00001)。与低剂量AL相比,高剂量AL在CA1区和CA3区造成了明显的神经元损伤(P < 0.03), CA3和CA1区的神经元对AL毒性最敏感,海马CA2区存活神经元数量最多,表明对AL毒性有抗性。讨论与结论:即使短期服用高剂量的AL,也会对大鼠大脑的不同区域产生不同程度的有害影响。本研究为深入探索AL化合物对人类参与者的毒理学奠定了基础,这可能对公共卫生具有重要意义。
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引用次数: 0
Philately, world postage stamps, history of medicine, and anatomists 集邮、世界邮票、医学史和解剖学家
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_152_22
Vishram Singh, B. Murlimanju, R. Vadgaonkar
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引用次数: 0
Unusual Multiple Arterial Variations of the Upper Limb 上肢不寻常的多动脉变异
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_208_21
B. Çandir, Latif Sağlam, İ. Gürses, Ö. Gayretli
During routine dissection of a 64-year-old male cadaver, multiple variations were observed in the arteries of the upper extremities. The first part of the axillary artery did not give any branches. The second part, after giving superior thoracic and thoracoacromial arteries divided into deep and superficial brachial arteries. Superficial brachial artery gave lateral thoracic artery and continued into the arm. After giving anterior circumflex humeral artery, the deep brachial artery trifurcated into the subscapular artery, posterior circumflex humeral artery, and profunda brachii artery. Understanding upper limb arterial variations are important for performing safer clinical procedures.
在一具64岁男性尸体的常规解剖过程中,观察到上肢动脉的多种变异。腋动脉的第一部分没有任何分支。第二部分,将胸上动脉和胸肩峰上动脉分为深臂动脉和浅臂动脉。臂浅动脉形成胸外侧动脉,并继续进入手臂。给予旋肱前动脉后,臂深动脉分叉为肩胛下动脉、旋肱后动脉和臂深动脉。了解上肢动脉变异对于执行更安全的临床程序非常重要。
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引用次数: 0
Evaluation of the Brain Indexes of Subjects with and without Brain Atrophy Using Computed Tomography 计算机断层扫描评价脑萎缩和非萎缩受试者的脑指标
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_20_22
Mahmut Öksüzler, S. Polat, Mahmut Tunç, Duygu Vurallı, P. Göker
Introduction: This study was undertaken to determine the values of brain indexes using computed tomography (CT) in our population. Material and Methods: This study was carried out on the 520 senior subjects (196 subjects having brain atrophy and 324 subjects having no brain atrophy) aged 60–90 years. Measurements of the brain indexes were taken from subjects having axial brain CT image in the radiology department. Furthermore, the data were analyzed according to age and gender. Results: The means and standard deviations of the measurements were as follows: the maximum distance between anterior horns, 37.35 ± 3.76 mm; minimum bicaudate nuclei distance, 20.76 ± 3.78 mm; maximum internal skull diameter, 135.66 ± 6.51 mm; maximum internal diameter of the frontal bone, 103.23 ± 6.23; internal skull diameter measured along the same line, 116.28 ± 6.60 mm; maximum external diameter of the skull, 144.08 ± 5.93 mm; and cella media width, 35.88 ± 6.93 mm; and the indices were calculated and found as follows: Huckman number, 58.11 ± 6.99 mm; bifrontal index, 0.36 ± 0.03; bicaudate frontal index, 0.55 ± 0.07; bicaudate index, 0.18 ± 0.03; bicaudate temporal index, 0.15 ± 0.03; and Schiersmann's index (SI), 4.22 ± 1.16 in subjects having brain atrophy. The same values were measured as 32.28 ± 3.19 mm; 15.32 ± 3.05 mm; 133.67 ± 6.71 mm; 102.05 ± 6.13 mm; 113.12 ± 6.04 mm; 141.14 ± 6.12 mm; 28.92 ± 5.79 mm; 47.59 ± 5.63 mm; 0.32 ± 0.03; 0.47 ± 0.08; 0.14 ± 0.03; 0.11 ± 0.02; and 5.09 ± 1.13 in healthy elderly subjects, respectively. There was a significant difference in all measurements (except SI) (P < 0.05). Discussion and Conclusion: The brain index dimensions of Turkish population provide important and useful knowledge for the clinicians in terms of comparison of abnormalities and atrophy of the brain.
引言:这项研究是为了在我们的人群中使用计算机断层扫描(CT)来确定大脑指标的值。材料和方法:本研究对520名60-90岁的老年受试者(196名患有脑萎缩,324名没有脑萎缩)进行。脑指标的测量是从放射科有轴向脑CT图像的受试者身上进行的。此外,还根据年龄和性别对数据进行了分析。结果:测量的平均值和标准偏差如下:前角之间的最大距离为37.35±3.76mm;双核最小距离为20.76±3.78mm;颅骨最大内径135.66±6.51mm;额骨最大内径为103.23±6.23;沿同一直线测量的颅骨内径为116.28±6.60mm;颅骨最大外径144.08±5.93mm;中池宽度为35.88±6.93mm;计算得出:Huckman数为58.11±6.99mm;双额指数0.36±0.03;双侧额指数,0.55±0.07;bicaudate指数,0.18±0.03;双焦日期时间指数,0.15±0.03;脑萎缩患者的Schiersmann指数(SI)为4.22±1.16。测得的相同值为32.28±3.19mm;15.32±3.05毫米;133.67±6.71毫米;102.05±6.13毫米;113.12±6.04毫米;141.14±6.12毫米;28.92±5.79毫米;47.59±5.63毫米;0.32±0.03;0.47±0.08;0.14±0.03;0.11±0.02;健康老年人分别为5.09±1.13。讨论和结论:土耳其人群的大脑指数维度为临床医生比较大脑异常和萎缩提供了重要而有用的知识。
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引用次数: 0
Anatomical variations of the human ossicular chain in south indian population: morphometry and morphology 南印度人群中人类听骨链的解剖变异:形态计量学和形态学
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_192_21
Giridhar Dasegowda, Padmalatha Kadirappa, Hema Nanjundaraju, S. Raja, Rachana Suresh
Introduction: The middle ear consists of the malleus, incus, and stapes. The otologic surgeons need to have a thorough knowledge of anatomical details and variations to provide better operative results and for surgical maneuvers. The present study aimed to analyze the morphological variation and morphometry of the ear ossicles and compare the parameters with those reported in previous studies. Material and Methods: The study was conducted on 28 mallei, 26 incus, and 20 stapes obtained from the cadavers allotted for dissection. Measurements were documented, and the morphological variations were analyzed. Results: The average of the parameters showed that the malleus was 7.59 mm in total length with an angle of 130°; the manubrium was 4.65 mm, the total length of the head and neck was 5.01 mm, and the average weight was 21.50 mg. The incus had a total length and width of 6.37 and 4.89 mm, respectively; a maximal distance of 5.97 mm between the tips with an angle of 101° and weighed an average of 23.81 mg. The stapes had a total length of 3.36 mm, with the stapedial base being 2.83 mm in length and 1.41 mm in width, and weighed an average of 3.16 mg. Discussion and Conclusion: The ossicular chain shows great variations in measurements and morphology. Hence, a thorough anatomical knowledge of the human ossicular chain is required for clinicians for surgical maneuvers and for designing prosthetics to replace the adult middle ear ossicles.
简介:中耳由锤骨、砧骨和镫骨组成。耳科外科医生需要对解剖细节和变异有全面的了解,以提供更好的手术效果和手术操作。本研究旨在分析耳小骨的形态学变化和形态计量学,并与以往的研究结果进行比较。材料与方法:选取待解剖尸体上的公跖骨28例,公跖骨26例,镫骨20例。测量结果被记录下来,形态变化被分析。结果:这些参数的平均值显示,锤骨总长度为7.59 mm,夹角为130°;柄柄4.65 mm,头颈总长5.01 mm,平均体重21.50 mg。砧木全长6.37 mm,宽4.89 mm;尖端之间的最大距离为5.97 mm,夹角为101°,平均重量为23.81 mg。雄蕊总长度3.36 mm,雄蕊基部长2.83 mm,宽1.41 mm,平均重3.16 mg。讨论与结论:听骨链在测量和形态上有很大的变化。因此,临床医生在手术操作和设计替代成人中耳小骨的假体时,需要对人类听骨链有全面的解剖学知识。
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引用次数: 0
Milder and Later Presentation of Trisomy 13: A Case Report and Literature Review Milder及其后对13三体的介绍:病例报告和文献综述
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_149_21
N. Rashmi, H. Kiran, H. Rajani
Patau syndrome or Trisomy 13 is the least common and most severe of the viable autosomal trisomies. The frequent clinical features include holoprosencephaly, polydactyly, flexion of the fingers, rocker-bottom feet, cleft lip and palate, neural tube defects, and heart defects, with neurological involvement being the most consistent one. It is usually recognized at birth by the typical birth defects with poor neurologic performance. About 85%‒90% of cases die during infancy, with only 5% to 10% of patients alive beyond 1 year. Patients surviving beyond 1 year have a severe developmental handicap. We present here an infant who came with a relatively milder form of Patau syndrome and was confirmed by karyotyping.
帕陶综合征或13三体是最不常见和最严重的常染色体三体。常见的临床特征包括前脑畸形、多指畸形、手指屈曲、脚摇底、唇腭裂、神经管缺损、心脏缺损等,其中以神经系统受累最为一致。通常在出生时通过典型的先天缺陷和较差的神经系统表现来识别。大约85%-90%的病例在婴儿期死亡,只有5% - 10%的患者存活超过1年。存活超过1年的患者有严重的发育障碍。我们在这里提出了一个婴儿谁来了一个相对温和的形式帕托综合征,并证实了核型。
{"title":"Milder and Later Presentation of Trisomy 13: A Case Report and Literature Review","authors":"N. Rashmi, H. Kiran, H. Rajani","doi":"10.4103/jasi.jasi_149_21","DOIUrl":"https://doi.org/10.4103/jasi.jasi_149_21","url":null,"abstract":"Patau syndrome or Trisomy 13 is the least common and most severe of the viable autosomal trisomies. The frequent clinical features include holoprosencephaly, polydactyly, flexion of the fingers, rocker-bottom feet, cleft lip and palate, neural tube defects, and heart defects, with neurological involvement being the most consistent one. It is usually recognized at birth by the typical birth defects with poor neurologic performance. About 85%‒90% of cases die during infancy, with only 5% to 10% of patients alive beyond 1 year. Patients surviving beyond 1 year have a severe developmental handicap. We present here an infant who came with a relatively milder form of Patau syndrome and was confirmed by karyotyping.","PeriodicalId":50010,"journal":{"name":"Journal of the Anatomical Society of India","volume":"71 1","pages":"321 - 323"},"PeriodicalIF":0.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48563516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship between Isolated Unilateral Concha Bullosa and Mastoid Air Cell Volumes 单侧离体大耳甲与乳突空气细胞体积的关系
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-10-01 DOI: 10.4103/jasi.jasi_164_21
F. Yuksel, M. Kahraman, Isa Deniz
Introduction: The purpose of this study was to investigate the relationship between the pneumatization of mastoid air cells (MACs) and isolated unilateral concha bullosa (CB) using computed tomography (CT) scans of the paranasal sinuses (PNS). Material and Methods: A retrospective review of PNS CT scans from 53 patients was performed. Cases with nasal septum angulation >5° were excluded from the study. CT evaluations were made with a 128-slice multislice CT scanner in two projections, axial and coronal. Slice thickness was taken as 1 mm for volumetric analysis. Volume measurements were calculated using the syngo.via software program by selecting the relevant anatomical region and using step-by-step addition and expansion processes. Volumes of the MACs (right and left) and isolated unilateral CB (right and left) were obtained and compared using statistical analysis. Results: The volume of MACs and isolated unilateral CB did not change with age; however, the volumes of male participants were larger than that of women. It was observed that the pneumatization of MACs on the side with isolated unilateral CB was significantly greater than for opposing MACs. Discussion and Conclusion: In our study, it was concluded that the isolated unilateral CB caused a significant increase in the MACs volume on the same side of CB.
前言:本研究的目的是利用鼻旁窦(PNS)的计算机断层扫描(CT)来研究乳突空气细胞(MACs)气化与孤立的单侧大耳甲(CB)之间的关系。材料和方法:对53例患者的PNS CT扫描进行回顾性分析。鼻中隔成角bbb50°的病例排除在研究之外。在128层多层螺旋CT上进行轴位和冠状两个投影。切片厚度取1mm进行体积分析。体积测量使用syngo计算。通过软件程序选择相关解剖区域,并采用一步一步的添加和扩展过程。取MACs(右侧和左侧)和离体单侧CB(右侧和左侧)的体积,并进行统计分析比较。结果:MACs和孤立的单侧CB体积不随年龄变化;然而,男性参与者的数量多于女性。我们观察到,孤立的单侧CB一侧的mac气化明显大于对侧mac。讨论与结论:在我们的研究中,我们得出结论,孤立的单侧脑脊灰引起脑脊灰同侧MACs体积的显著增加。
{"title":"The Relationship between Isolated Unilateral Concha Bullosa and Mastoid Air Cell Volumes","authors":"F. Yuksel, M. Kahraman, Isa Deniz","doi":"10.4103/jasi.jasi_164_21","DOIUrl":"https://doi.org/10.4103/jasi.jasi_164_21","url":null,"abstract":"Introduction: The purpose of this study was to investigate the relationship between the pneumatization of mastoid air cells (MACs) and isolated unilateral concha bullosa (CB) using computed tomography (CT) scans of the paranasal sinuses (PNS). Material and Methods: A retrospective review of PNS CT scans from 53 patients was performed. Cases with nasal septum angulation >5° were excluded from the study. CT evaluations were made with a 128-slice multislice CT scanner in two projections, axial and coronal. Slice thickness was taken as 1 mm for volumetric analysis. Volume measurements were calculated using the syngo.via software program by selecting the relevant anatomical region and using step-by-step addition and expansion processes. Volumes of the MACs (right and left) and isolated unilateral CB (right and left) were obtained and compared using statistical analysis. Results: The volume of MACs and isolated unilateral CB did not change with age; however, the volumes of male participants were larger than that of women. It was observed that the pneumatization of MACs on the side with isolated unilateral CB was significantly greater than for opposing MACs. Discussion and Conclusion: In our study, it was concluded that the isolated unilateral CB caused a significant increase in the MACs volume on the same side of CB.","PeriodicalId":50010,"journal":{"name":"Journal of the Anatomical Society of India","volume":"71 1","pages":"311 - 316"},"PeriodicalIF":0.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70780960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Description of an atypical vascular arch in the renal parenchyma 肾实质非典型血管弓的描述
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-07-01 DOI: 10.4103/jasi.jasi_83_21
Alberto Barrios, A. C. Cisneros Gimeno, Jesus Nogue, J. Orozco
Introduction: Variability in renal vascularization occurs with a frequency of around 30%. During the routine dissection of one cadaver without renal pathology, we revealed the presence of one. Material and Methods: Dissection of a cadaver carried out in the practicing room of School of Medicine. Results: During the routine dissection of one cadaver without renal pathology, we revealed the presence of an early bifurcation of the renal artery on the left side, and the presence of two polar arteries – superior and inferior -, the latter presenting an anterior and posterior vascular arch to the renal pelvis in the parenchyma, which anastomoses the pre- and retro-pyelic branches of the renal artery with the pre- and retro-pyelic branches of the inferior accessory polar artery. In addition, the presence of an accessory polar artery was observed in the right kidney. Discussion and Conclusion: For vascular surgeons, knowledge of this anatomical variation is of real clinical relevance in cases such as fenestrated endografting in order to preserve the function of the entire kidney.
引言:肾血管形成的变异发生率约为30%。在对一具没有肾脏病理的尸体进行常规解剖时,我们发现了一具尸体。材料与方法:在医学院实习室对一具尸体进行解剖。结果:在对一具无肾脏病理的尸体进行常规解剖时,我们发现左侧肾动脉存在早期分叉,并存在两条极动脉——上动脉和下动脉,后者在实质中与肾盂形成前后血管弓,其将肾动脉的肾盂前支和肾盂后支与下副极动脉的肾盂后支和肾盂前支吻合。此外,在右肾中观察到一条副极动脉的存在。讨论和结论:对于血管外科医生来说,了解这种解剖变异在开窗内移植物等情况下具有真正的临床意义,以保护整个肾脏的功能。
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引用次数: 0
Variations of the circle of willis determined via magnetic resonance angiography: A single-center analysis of the serbian population 通过磁共振血管造影确定威利斯圈的变化:塞尔维亚人口的单中心分析
IF 0.4 4区 医学 Q4 ANATOMY & MORPHOLOGY Pub Date : 2022-07-01 DOI: 10.4103/jasi.jasi_78_20
Mimoza Ðevukaj, I. Nosek, Miloš Vuković, D. Kozic
Introduction: The circle of Willis (CoW) represents the collateral pathway between large brain-feeding arteries, the knowledge of which is important in interventional and neurosurgical procedures, in the diagnosis and planning of procedures in acute stroke and subarachnoid hemorrhage. Aim: The study aims to determine the prevalence of variations of the CoW in patients from Serbia via magnetic resonance angiography (MRA). Material and Methods: The study was conducted as a retrospective study at the Center for Imaging Diagnostics, Oncology Institute of Vojvodina. Magnetic resonance imaging was analyzed in 665 patients of both sexes (471 females and 194 males), who underwent MRA during 2018 and 2019. Results: Complete CoW was found in 48.42% of cases, mostly in females (68.01%). Partially complete CoW and incomplete CoW were encountered in 38.05% and 13.55% of patients, mostly in females (73.52% and 73.33%). Anterior circulation variations were seen in 27.41% of cases, higher in females (63.83%), most commonly A1 anterior cerebral artery hypoplasia (9.32%). Posterior circulation variations were seen in 46.36% of cases, higher in females (79.25%), most commonly posterior communicating (PCom) artery hypoplasia (25.56%). Combined variations were seen in 26.24% of patients, with higher prevalence in females (73.33%). The prevalence of variations of posterior circulation between male and female patients was statistically significant (P = 0.007) and was higher in females. Discussion and Conclusion: This study showed that the most common variations were that of the posterior circulation, most commonly PCom artery hypoplasia. Complete CoW was found in <50% of cases (48.42%).
导语:威利斯圈(CoW)代表脑供血大动脉之间的侧支通路,对其的认识在介入和神经外科手术、急性脑卒中和蛛网膜下腔出血的诊断和手术计划中具有重要意义。目的:该研究旨在通过磁共振血管造影(MRA)确定塞尔维亚患者中奶牛变异的患病率。材料和方法:本研究是在伏伊伏丁那肿瘤研究所影像诊断中心进行的回顾性研究。对2018年至2019年期间接受MRA治疗的665名男女患者(女性471名,男性194名)的磁共振成像进行了分析。结果:全母牛占48.42%,以女性居多(68.01%)。部分完全性奶牛和不完全性奶牛分别占38.05%和13.55%,以女性为主(分别为73.52%和73.33%)。前循环病变占27.41%,女性较高(63.83%),最常见的是A1型大脑前动脉发育不全(9.32%)。46.36%的病例出现后循环变化,女性较高(79.25%),最常见的是后交通(PCom)动脉发育不全(25.56%)。26.24%的患者出现联合变异,其中女性较高(73.33%)。男性和女性患者的后循环变异率有统计学意义(P = 0.007),女性患者更高。讨论与结论:本研究显示最常见的变异是后循环,最常见的是PCom动脉发育不全。完全CoW发生率<50%(48.42%)。
{"title":"Variations of the circle of willis determined via magnetic resonance angiography: A single-center analysis of the serbian population","authors":"Mimoza Ðevukaj, I. Nosek, Miloš Vuković, D. Kozic","doi":"10.4103/jasi.jasi_78_20","DOIUrl":"https://doi.org/10.4103/jasi.jasi_78_20","url":null,"abstract":"Introduction: The circle of Willis (CoW) represents the collateral pathway between large brain-feeding arteries, the knowledge of which is important in interventional and neurosurgical procedures, in the diagnosis and planning of procedures in acute stroke and subarachnoid hemorrhage. Aim: The study aims to determine the prevalence of variations of the CoW in patients from Serbia via magnetic resonance angiography (MRA). Material and Methods: The study was conducted as a retrospective study at the Center for Imaging Diagnostics, Oncology Institute of Vojvodina. Magnetic resonance imaging was analyzed in 665 patients of both sexes (471 females and 194 males), who underwent MRA during 2018 and 2019. Results: Complete CoW was found in 48.42% of cases, mostly in females (68.01%). Partially complete CoW and incomplete CoW were encountered in 38.05% and 13.55% of patients, mostly in females (73.52% and 73.33%). Anterior circulation variations were seen in 27.41% of cases, higher in females (63.83%), most commonly A1 anterior cerebral artery hypoplasia (9.32%). Posterior circulation variations were seen in 46.36% of cases, higher in females (79.25%), most commonly posterior communicating (PCom) artery hypoplasia (25.56%). Combined variations were seen in 26.24% of patients, with higher prevalence in females (73.33%). The prevalence of variations of posterior circulation between male and female patients was statistically significant (P = 0.007) and was higher in females. Discussion and Conclusion: This study showed that the most common variations were that of the posterior circulation, most commonly PCom artery hypoplasia. Complete CoW was found in <50% of cases (48.42%).","PeriodicalId":50010,"journal":{"name":"Journal of the Anatomical Society of India","volume":"71 1","pages":"220 - 224"},"PeriodicalIF":0.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46408903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of the Anatomical Society of India
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