Schematic orthogonal arrays are closely related to association schemes. And which orthogonal arrays are schematic orthogonal arrays and how to classify them is an open problem proposed by Hedayat et al. (1999). By using the Hamming distances, this paper presents some general methods for constructing schematic symmetric and mixed orthogonal arrays of high strength. As applications of these methods, we construct association schemes and many new schematic orthogonal arrays including several infinite classes of such arrays. Some examples are provided to illustrate the construction methods. The paper gives the partial solution of the problem by Hedayat et al. (1999) for symmetric and mixed orthogonal arrays of high strength.
A frequent challenge encountered in real-world applications is data having a high proportion of zeros. Focusing on ecological abundance data, much attention has been given to zero-inflated count data. Models for non-negative continuous abundance data with an excess of zeros are rarely discussed. Work presented here considers the creation of a point mass at zero through a left-censoring approach or through a hurdle approach. We incorporate both mechanisms to capture the analog of zero-inflation for count data. Additionally, primary attention has been given to univariate zero-inflated modeling (e.g., single species), whereas data often arise jointly (e.g., a collection of species). With multivariate abundance data, a key issue is to capture dependence among the species at a site, both in terms of positive abundance as well as absence. Therefore, our contribution is a model for multivariate zero-inflated continuous data that are non-negative. Working in a Bayesian framework, we discuss the issue of separating the two sources of zeros and offer model comparison metrics for multivariate zero-inflated data. In an application, we model the total biomass for five tree species obtained from plots established in the Forest Inventory Analysis database in the Northeast region of the United States.
The Cox model with unspecified baseline hazard is often used to model survival data. In the case of correlated event times, this model can be extended by introducing random effects, also called frailty terms, leading to the frailty model. Few methods have been put forward to estimate parameters of such frailty models, and they often consider only a particular distribution for the frailty terms and specific correlation structures. In this paper, a new efficient method is introduced to perform parameter estimation by maximizing the integrated partial likelihood. The proposed stochastic estimation procedure can deal with frailty models with a broad choice of distributions for the frailty terms and with any kind of correlation structure between the frailty components, also allowing random interaction terms between the covariates and the frailty components. The almost sure convergence of the stochastic estimation algorithm towards a critical point of the integrated partial likelihood is proved. Numerical convergence properties are evaluated through simulation studies and comparison with existing methods is performed. In particular, the robustness of the proposed method with respect to different parametric baseline hazards and misspecified frailty distributions is demonstrated through simulation. Finally, the method is applied to a mastitis and a bladder cancer dataset.