首页 > 最新文献

Journal of Clinical Densitometry最新文献

英文 中文
Proceedings of the 2024 Santa Fe Bone Symposium: Update on the Management of Osteoporosis and Rare Bone Diseases 2024年圣达菲骨研讨会论文集:骨质疏松症和罕见骨疾病管理的最新进展。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101559
E. Michael Lewiecki , John P. Bilezikian , Amanda Clark , Michael T. Collins , Deborah M. Kado , Joseph Lane , Bente Langdahl , Michael R. McClung , Peter J. Snyder , Emily M. Stein
The 24th Annual Santa Fe Bone Symposium (SFBS) was held in Santa Fe, New Mexico, USA, on August 2-3, 2024. This was a “hybrid” meeting, with in-person and real-time remote participants representing a broad range of geographical locations and medical disciplines. The focus was on new developments in the care of patients with osteoporosis, other metabolic bone diseases, and inherited skeletal disorders. The most current medical evidence was presented and discussed with consideration of implications for patient management. Topics included an update on clinical uses of osteoanabolic agents, management of patients discontinuing denosumab, bone health optimization for orthopedic surgery, estrogen and testosterone in the management of osteoporosis, osteoporosis treatment in the very old, overview of rare bone diseases, treat-to-target for osteoporosis, and a progress report on global activities of Bone Health ECHO. There were two highly interactive faculty panel discussions – one with case presentations by attendees and another with open microphone for all topics of interest. Endocrinology fellows, selected from attendees of the Santa Fe Fellows Workshop on Metabolic Bone Diseases, held the two days preceding the SFBS, participated with presentations of oral abstracts. Ancillary events addressed modern approaches to menopause and bone health, case studies of management of patients at very high fracture risk, and management of patients with rare bone diseases, such as hypophosphatasia, fibrodysplasia ossificans progressiva, X-linked hypophosphatemia, and hypoparathyroidism. These proceedings of the SFBS present the clinical highlights of the plenary sessions and the discussions that followed.
2024年8月2日至3日,第24届圣达菲年度骨骼研讨会(SFBS)在美国新墨西哥州圣达菲举行。这是一次“混合型”会议,现场和实时远程与会者代表了广泛的地理位置和医学学科。会议的重点是骨质疏松症、其他代谢性骨病和遗传性骨骼疾病患者护理的新进展。提出并讨论了最新的医学证据,并考虑了对患者管理的影响。主题包括骨合成代谢药物的临床应用、停用denosumab患者的管理、骨科手术的骨健康优化、骨质疏松症的雌激素和睾酮治疗、老年人骨质疏松症的治疗、罕见骨病的概述、骨质疏松症的治疗目标,以及骨健康ECHO全球活动的进展报告。有两个高度互动的教师小组讨论-一个是与会者的案例演示,另一个是开放的麦克风,所有感兴趣的话题。在SFBS前两天举行的圣达菲代谢性骨病研讨会上,内分泌学研究员从与会者中选出,并进行了口头摘要的介绍。辅助活动涉及更年期和骨骼健康的现代方法,非常高骨折风险患者的管理案例研究,以及罕见骨病患者的管理,如低磷血症、进行性骨化纤维发育不良、x连锁低磷血症和甲状旁腺功能低下。SFBS的这些会议记录展示了全体会议和随后的讨论的临床亮点。
{"title":"Proceedings of the 2024 Santa Fe Bone Symposium: Update on the Management of Osteoporosis and Rare Bone Diseases","authors":"E. Michael Lewiecki ,&nbsp;John P. Bilezikian ,&nbsp;Amanda Clark ,&nbsp;Michael T. Collins ,&nbsp;Deborah M. Kado ,&nbsp;Joseph Lane ,&nbsp;Bente Langdahl ,&nbsp;Michael R. McClung ,&nbsp;Peter J. Snyder ,&nbsp;Emily M. Stein","doi":"10.1016/j.jocd.2024.101559","DOIUrl":"10.1016/j.jocd.2024.101559","url":null,"abstract":"<div><div>The 24<sup>th</sup> Annual Santa Fe Bone Symposium (SFBS) was held in Santa Fe, New Mexico, USA, on August 2-3, 2024. This was a “hybrid” meeting, with in-person and real-time remote participants representing a broad range of geographical locations and medical disciplines. The focus was on new developments in the care of patients with osteoporosis, other metabolic bone diseases, and inherited skeletal disorders. The most current medical evidence was presented and discussed with consideration of implications for patient management. Topics included an update on clinical uses of osteoanabolic agents, management of patients discontinuing denosumab, bone health optimization for orthopedic surgery, estrogen and testosterone in the management of osteoporosis, osteoporosis treatment in the very old, overview of rare bone diseases, treat-to-target for osteoporosis, and a progress report on global activities of Bone Health ECHO. There were two highly interactive faculty panel discussions – one with case presentations by attendees and another with open microphone for all topics of interest. Endocrinology fellows, selected from attendees of the Santa Fe Fellows Workshop on Metabolic Bone Diseases, held the two days preceding the SFBS, participated with presentations of oral abstracts. Ancillary events addressed modern approaches to menopause and bone health, case studies of management of patients at very high fracture risk, and management of patients with rare bone diseases, such as hypophosphatasia, fibrodysplasia ossificans progressiva, X-linked hypophosphatemia, and hypoparathyroidism. These proceedings of the SFBS present the clinical highlights of the plenary sessions and the discussions that followed.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101559"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship of Skeletal Muscle Mass, Length of Sports Experience, and Sexual Maturity with Bone Density and Geometry in Adolescent Athletes 青少年运动员骨骼肌质量、运动经验长度和性成熟程度与骨密度和几何形状的关系。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2025.101562
Mateus Augusto Bim , Tiago Rodrigues de Lima , Rafael Martins , Clair Costa Miranda , Rômulo Araújo Fernandes , Andreia Pelegrini
Objective: To identify the relationship between length of sports experience, muscle mass, and sexual maturity with bone mineral density (BMD) and geometry in adolescent basketball and track and field athletes.
Method: The study included adolescent (11–18 years) athletes, of both sexes, who practiced basketball (n = 26) or track and field (n = 24). Skeletal muscle mass was measured by bioelectrical impedance analysis. Data on sports training and sexual maturity were collected through a questionnaire. Total body, lumbar, femoral, and forearm BMD were determined by dual-energy X-ray absorptiometry. Femoral scans were used to generate bone geometry measurements (femur strength index, cross-sectional area, cross-sectional moment of inertia, section modulus, and buckling ratio). Bone outcomes were compared between modalities by the Mann–Whitney U-test or Student's t-test and by analysis of covariance with adjustment for sports experience, sexual maturity, and skeletal muscle mass.
Results: In the crude analysis, the basketball group had higher mean values for height, body weight, muscle mass, femoral neck BMD, cross-sectional area, and cross-sectional moment of inertia. In the covariate-adjusted analysis, the track and field group had higher total-body-less-head (0.995 vs. 1.035, p = 0.043), lumbar (1.012 vs. 1.107, p = 0.005), and radial (0.734 vs. 0.800, p = 0.005) BMD. Muscle mass was the main covariate influencing bone parameters, followed by sexual maturity.
Conclusion: Skeletal muscle mass was the main determinant of bone outcomes in adolescent athletes, followed by sexual maturity, underscoring the importance of considering these variables when assessing bone health in this population.
目的:探讨青少年篮球、田径运动员运动经历长度、肌肉量、性成熟程度与骨密度和几何形状的关系。方法:研究对象为青少年(11-18岁)篮球运动员(n = 26)和田径运动员(n = 24),男女不限。采用生物电阻抗法测定骨骼肌质量。通过问卷调查收集运动训练和性成熟的数据。采用双能x线骨密度仪测定全身、腰椎、股骨和前臂骨密度。股骨扫描用于生成骨几何测量(股骨强度指数、横截面面积、横截面惯性矩、截面模量和屈曲比)。通过Mann-Whitney u检验或Student’st检验,通过协方差分析,调整运动经验、性成熟和骨骼肌质量,比较不同模式的骨骼结果。结果:在粗分析中,篮球组的身高、体重、肌肉质量、股骨颈骨密度、横截面积和横截惯性矩的平均值较高。在协变量调整分析中,田径组有更高的全身-头部(0.995比1.035,p = 0.043)、腰椎(1.012比1.107,p = 0.005)和桡骨(0.734比0.800,p = 0.005)骨密度。肌肉质量是影响骨骼参数的主要协变量,其次是性成熟。结论:骨骼肌质量是青少年运动员骨骼结果的主要决定因素,其次是性成熟,强调了在评估这一人群的骨骼健康时考虑这些变量的重要性。
{"title":"Relationship of Skeletal Muscle Mass, Length of Sports Experience, and Sexual Maturity with Bone Density and Geometry in Adolescent Athletes","authors":"Mateus Augusto Bim ,&nbsp;Tiago Rodrigues de Lima ,&nbsp;Rafael Martins ,&nbsp;Clair Costa Miranda ,&nbsp;Rômulo Araújo Fernandes ,&nbsp;Andreia Pelegrini","doi":"10.1016/j.jocd.2025.101562","DOIUrl":"10.1016/j.jocd.2025.101562","url":null,"abstract":"<div><div><em>Objective:</em> To identify the relationship between length of sports experience, muscle mass, and sexual maturity with bone mineral density (BMD) and geometry in adolescent basketball and track and field athletes.</div><div><em>Method:</em> The study included adolescent (11–18 years) athletes, of both sexes, who practiced basketball (<em>n</em> = 26) or track and field (<em>n</em> = 24). Skeletal muscle mass was measured by bioelectrical impedance analysis. Data on sports training and sexual maturity were collected through a questionnaire. Total body, lumbar, femoral, and forearm BMD were determined by dual-energy X-ray absorptiometry. Femoral scans were used to generate bone geometry measurements (femur strength index, cross-sectional area, cross-sectional moment of inertia, section modulus, and buckling ratio). Bone outcomes were compared between modalities by the Mann–Whitney <em>U</em>-test or Student's <em>t</em>-test and by analysis of covariance with adjustment for sports experience, sexual maturity, and skeletal muscle mass.</div><div><em>Results:</em> In the crude analysis, the basketball group had higher mean values for height, body weight, muscle mass, femoral neck BMD, cross-sectional area, and cross-sectional moment of inertia. In the covariate-adjusted analysis, the track and field group had higher total-body-less-head (0.995 <em>vs.</em> 1.035, <em>p</em> = 0.043), lumbar (1.012 <em>vs.</em> 1.107, <em>p</em> = 0.005), and radial (0.734 <em>vs.</em> 0.800, <em>p</em> = 0.005) BMD. Muscle mass was the main covariate influencing bone parameters, followed by sexual maturity.</div><div><em>Conclusion:</em> Skeletal muscle mass was the main determinant of bone outcomes in adolescent athletes, followed by sexual maturity, underscoring the importance of considering these variables when assessing bone health in this population.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101562"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-Calibration of Areal Bone Mineral Densities and Body Composition between DMS Stratos and Hologic Horizon A Dual-Energy X-ray Absorptiometers: The Effect of Body Mass Index DMS Stratos和Hologic Horizon A双能x射线吸收仪间骨矿物质密度和身体成分的交叉校准:体质指数的影响。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101553
Laurent Maïmoun , Sandrine Alonso , Krishna Kunal Mahadea , Julien Dubois , Tom Paunet , Florentin Kucharczak , Lisa Maïmoun Nande , Vincent Boudousq , Thibault Mura , Denis Mariano-Goulart
Purpose: The aim of this study was to investigate the correlations between areal bone mineral density (aBMD) and body composition measured by two dual-energy X-ray absorptiometers (DXA), the DMS Stratos® (STR) and the Hologic Horizon A® (HRZ), and then generate cross-calibration equations between the two scanners.
Methods: Repeat scans were obtained from 251 adults (85 % female), 36 ± 14 years old with mean body mass index (BMI) of 28.7 ± 11.1 kg/m2, using HRZ (fan-beam technology) and STR (pencil-beam technology). aBMD was measured at whole body [WB], femoral neck [FN], total hip [TH], lumbar spine [LS] and radius, while fat mass [FM] and lean tissue mass [LTM] were determined at whole body and at android and gynoid subregions.
Results: Compared to HRZ, STR underestimated both aBMD at WB and radius and LTM at WB and android and gynoid regions. Conversely, STR overestimated aBMD at FN, TH, LS and FM at WB android and gynoid regions. Except for WB bone mineral content (r = 0.87) and WB aBMD (r = 0.84), there were strong correlations of aBMD and body composition between the two DXAs (r > 0.91; p < 0.0001). Several of the parameters that required the determination of specific cross-calibration equations because of the significant bias between the two DXAs were found to be influenced by BMI.
Conclusions: Although the data from the STR and the HRZ were highly correlated for aBMD and body composition parameters, a systematic measurement bias between two DXAs was observed. The development of cross-calibration equations fully corrected these differences and they may thus be useful for multicenter studies when scans are performed with STR and HRZ.
目的:研究DMS Stratos®(STR)和Hologic Horizon A®(HRZ)两种双能x射线吸收仪(DXA)测量的面骨矿物质密度(aBMD)与人体成分的相关性,并建立两种扫描仪之间的交叉校准方程。方法:采用扇形波束技术(HRZ)和铅笔波束技术(STR)对251名成人(85% %女性),36名 ± 14岁,平均体重指数(BMI) 28.7 ± 11.1 kg/m2进行重复扫描。测定全身[WB]、股骨颈[FN]、全髋[TH]、腰椎[LS]和桡骨的aBMD,测定全身、机器人和女性骨亚区脂肪量[FM]和瘦组织量[LTM]。结果:与HRZ相比,STR低估了WB和桡骨区的aBMD,低估了WB、android和gynyl区域的LTM。相反,STR高估了WB机器人和gynoid区域的FN、TH、LS和FM的aBMD。除了WB骨矿物质含量(r = 0.87)和WB aBMD (r = 0.84)外,两种DXAs之间的aBMD与体成分有很强的相关性(r > 0.91;p 结论:虽然STR和HRZ的数据与aBMD和体成分参数高度相关,但两种dxa之间存在系统性的测量偏差。交叉校准方程的发展完全纠正了这些差异,因此,当使用STR和HRZ进行扫描时,它们可能对多中心研究有用。
{"title":"Cross-Calibration of Areal Bone Mineral Densities and Body Composition between DMS Stratos and Hologic Horizon A Dual-Energy X-ray Absorptiometers: The Effect of Body Mass Index","authors":"Laurent Maïmoun ,&nbsp;Sandrine Alonso ,&nbsp;Krishna Kunal Mahadea ,&nbsp;Julien Dubois ,&nbsp;Tom Paunet ,&nbsp;Florentin Kucharczak ,&nbsp;Lisa Maïmoun Nande ,&nbsp;Vincent Boudousq ,&nbsp;Thibault Mura ,&nbsp;Denis Mariano-Goulart","doi":"10.1016/j.jocd.2024.101553","DOIUrl":"10.1016/j.jocd.2024.101553","url":null,"abstract":"<div><div><em>Purpose:</em> The aim of this study was to investigate the correlations between areal bone mineral density (aBMD) and body composition measured by two dual-energy X-ray absorptiometers (DXA), the DMS Stratos® (STR) and the Hologic Horizon A® (HRZ), and then generate cross-calibration equations between the two scanners.</div><div><em>Methods:</em> Repeat scans were obtained from 251 adults (85 % female), 36 ± 14 years old with mean body mass index (BMI) of 28.7 ± 11.1 kg/m2, using HRZ (fan-beam technology) and STR (pencil-beam technology). aBMD was measured at whole body [WB], femoral neck [FN], total hip [TH], lumbar spine [LS] and radius, while fat mass [FM] and lean tissue mass [LTM] were determined at whole body and at android and gynoid subregions.</div><div><em>Results:</em> Compared to HRZ, STR underestimated both aBMD at WB and radius and LTM at WB and android and gynoid regions. Conversely, STR overestimated aBMD at FN, TH, LS and FM at WB android and gynoid regions. Except for WB bone mineral content (r = 0.87) and WB aBMD (r = 0.84), there were strong correlations of aBMD and body composition between the two DXAs (r &gt; 0.91; p &lt; 0.0001). Several of the parameters that required the determination of specific cross-calibration equations because of the significant bias between the two DXAs were found to be influenced by BMI.</div><div><em>Conclusions:</em> Although the data from the STR and the HRZ were highly correlated for aBMD and body composition parameters, a systematic measurement bias between two DXAs was observed. The development of cross-calibration equations fully corrected these differences and they may thus be useful for multicenter studies when scans are performed with STR and HRZ.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101553"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to ‘Executive Summary of the 2023 Adult Position Development Conference of the International Society for Clinical Densitometry: DXA Reporting, Follow-up BMD Testing and Trabecular Bone Score Application and Reporting’ Journal of Clinical Densitometry Volume 27, Issue 1, January–March 2024, 101435 《临床密度测量学杂志》第27卷,第1期,2024年1月- 3月,101435,《2023年国际临床密度测量学会成人体位发展会议执行摘要:DXA报告,后续BMD测试和小梁骨评分应用和报告》的勘误表。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101548
Christopher Shuhart , Angela Cheung , Ranjodh Gill , Linsey Gani , Heenam Goel , Auryan Szalat
{"title":"Corrigendum to ‘Executive Summary of the 2023 Adult Position Development Conference of the International Society for Clinical Densitometry: DXA Reporting, Follow-up BMD Testing and Trabecular Bone Score Application and Reporting’ Journal of Clinical Densitometry Volume 27, Issue 1, January–March 2024, 101435","authors":"Christopher Shuhart ,&nbsp;Angela Cheung ,&nbsp;Ranjodh Gill ,&nbsp;Linsey Gani ,&nbsp;Heenam Goel ,&nbsp;Auryan Szalat","doi":"10.1016/j.jocd.2024.101548","DOIUrl":"10.1016/j.jocd.2024.101548","url":null,"abstract":"","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101548"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Health ECHO Case Report: Significant Elevation in Bone Turnover Markers and Progression of Vertebral Fractures After Denosumab Discontinuation Followed by a PTH-Analog 骨健康ECHO病例报告:Denosumab停药后pth类似物导致骨转换标志物显著升高和椎体骨折进展
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101551
Yevgeniya Kushchayeva , Sergiy Kushchayev , Kimberly Dunn , Iryna Pestun , Micol S. Rothman , E. Michael Lewiecki
Bone Health ECHO (Extension for Community Healthcare Outcomes) is a virtual community of practice, where healthcare professionals have met via videoconferencing weekly since 2015. This model of learning is focused on short didactics and the presentation of real but de-identified patient cases followed by highly interactive discussions. These are often clinical situations with diagnostic and therapeutic dilemmas that are not readily addressed by randomized placebo-controlled clinical trials and clinical practice guidelines. Here we present the case of a woman with postmenopausal osteoporosis with adverse consequences following discontinuation of denosumab and uncertainties on next steps for management. This case highlights the relevance of selection of the initial bone-targeted medication and the sequence of therapy in osteoporosis management.
骨健康ECHO(社区医疗保健结果扩展)是一个虚拟的实践社区,自2015年以来,医疗保健专业人员每周通过视频会议举行会议。这种学习模式侧重于简短的教学和真实但不确定的患者病例的呈现,然后是高度互动的讨论。这些通常是具有诊断和治疗困境的临床情况,随机安慰剂对照临床试验和临床实践指南不容易解决这些问题。在这里,我们提出了一例绝经后骨质疏松症的妇女,在停用denosumab后出现不良后果,并且不确定下一步的管理步骤。本病例强调了在骨质疏松症治疗中选择初始骨靶向药物和治疗顺序的相关性。
{"title":"Bone Health ECHO Case Report: Significant Elevation in Bone Turnover Markers and Progression of Vertebral Fractures After Denosumab Discontinuation Followed by a PTH-Analog","authors":"Yevgeniya Kushchayeva ,&nbsp;Sergiy Kushchayev ,&nbsp;Kimberly Dunn ,&nbsp;Iryna Pestun ,&nbsp;Micol S. Rothman ,&nbsp;E. Michael Lewiecki","doi":"10.1016/j.jocd.2024.101551","DOIUrl":"10.1016/j.jocd.2024.101551","url":null,"abstract":"<div><div>Bone Health ECHO (Extension for Community Healthcare Outcomes) is a virtual community of practice, where healthcare professionals have met via videoconferencing weekly since 2015. This model of learning is focused on short didactics and the presentation of real but de-identified patient cases followed by highly interactive discussions. These are often clinical situations with diagnostic and therapeutic dilemmas that are not readily addressed by randomized placebo-controlled clinical trials and clinical practice guidelines. Here we present the case of a woman with postmenopausal osteoporosis with adverse consequences following discontinuation of denosumab and uncertainties on next steps for management. This case highlights the relevance of selection of the initial bone-targeted medication and the sequence of therapy in osteoporosis management.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101551"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Health ECHO Case Report: High Bone Mass in a Patient with Chronic Kidney Disease 骨健康ECHO病例报告:1例慢性肾病患者骨量增高。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101554
Zhanna Belaya , Elena Przhiyalkovskaya , Elizaveta Mamedova , Sofia Gronskaia , Natalia Tarbaeva , Margarita Sharova , Sergey Popov , Michael Lewiecki
Bone Health ECHO (Extension of Community Healthcare Outcomes) is a growing family of online educational programs. Its mission is to enhance delivery of best practice skeletal healthcare worldwide. Each program typically consists of a didactic lecture and discussion of clinical cases with diagnostic and treatment dilemmas. Here we present a Bone Health ECHO case of a 39-year-old man who has received hemodialysis for 12 years. This case is characterized by the development of chronic kidney disease - mineral and bone disorder (CKD-MBD) which was managed using conservative treatment to maintain phosphate and calcium levels within the reference range in spite of severe secondary hyperparathyroidism, after the patient declined parathyroidectomy. Although this patient had multiple vertebral fractures with height loss, his bone mineral density was higher than expected for his age and gradually increased over the period of observation. Whole-exome sequencing showed a heterozygous, likely pathogenic variant in LEMD3 gene (13 exon HG38, chr12:65246271dup, с.2682dup in a heterozygous state), which may explain the high bone mass phenotype. As a result of the ECHO presentation, we decided that successful treatment of CKD-MBD would be the most effective approach to managing his bone fragility. His high bone mass phenotype was most likely associated with LEMD3 gene variant. This patient does not require any specific anti-osteoporotic treatment at this time; however, he is likely to benefit from parathyroid surgery.
骨健康ECHO(社区医疗保健结果扩展)是一个正在成长的在线教育项目。其使命是加强全球骨骼保健最佳实践的交付。每个项目通常包括教学讲座和临床病例的诊断和治疗困境的讨论。在这里,我们提出了一个39岁的男性接受血液透析12年的骨健康回声病例。该病例的特点是慢性肾脏疾病-矿物质和骨骼疾病(CKD-MBD)的发展,尽管患者拒绝甲状旁腺切除术后出现严重的继发性甲状旁腺功能亢进,但仍采用保守治疗将磷酸盐和钙水平维持在参考范围内。虽然该患者有多处椎体骨折并伴有高度下降,但其骨密度高于同龄患者的预期,并在观察期间逐渐升高。全外显子组测序结果显示LEMD3基因(13外显子HG38, chr12:65246271dup, p < 0.05)存在杂合子,可能具有致病性。2682dup处于杂合状态),这可能解释了高骨量表型。根据ECHO的报告,我们认为CKD-MBD的成功治疗将是控制他骨骼脆弱性的最有效方法。其高骨量表型极有可能与LEMD3基因变异有关。该患者此时不需要任何特定的抗骨质疏松治疗;然而,他可能会从甲状旁腺手术中获益。
{"title":"Bone Health ECHO Case Report: High Bone Mass in a Patient with Chronic Kidney Disease","authors":"Zhanna Belaya ,&nbsp;Elena Przhiyalkovskaya ,&nbsp;Elizaveta Mamedova ,&nbsp;Sofia Gronskaia ,&nbsp;Natalia Tarbaeva ,&nbsp;Margarita Sharova ,&nbsp;Sergey Popov ,&nbsp;Michael Lewiecki","doi":"10.1016/j.jocd.2024.101554","DOIUrl":"10.1016/j.jocd.2024.101554","url":null,"abstract":"<div><div>Bone Health ECHO (Extension of Community Healthcare Outcomes) is a growing family of online educational programs. Its mission is to enhance delivery of best practice skeletal healthcare worldwide. Each program typically consists of a didactic lecture and discussion of clinical cases with diagnostic and treatment dilemmas. Here we present a Bone Health ECHO case of a 39-year-old man who has received hemodialysis for 12 years. This case is characterized by the development of chronic kidney disease - mineral and bone disorder (CKD-MBD) which was managed using conservative treatment to maintain phosphate and calcium levels within the reference range in spite of severe secondary hyperparathyroidism, after the patient declined parathyroidectomy. Although this patient had multiple vertebral fractures with height loss, his bone mineral density was higher than expected for his age and gradually increased over the period of observation. Whole-exome sequencing showed a heterozygous, likely pathogenic variant in <em>LEMD3</em> gene (13 exon HG38, chr12:65246271dup, с.2682dup in a heterozygous state), which may explain the high bone mass phenotype. As a result of the ECHO presentation, we decided that successful treatment of CKD-MBD would be the most effective approach to managing his bone fragility. His high bone mass phenotype was most likely associated with <em>LEMD3</em> gene variant. This patient does not require any specific anti-osteoporotic treatment at this time; however, he is likely to benefit from parathyroid surgery.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101554"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcaneal Bone Mineral Assessment in Elite Female Trail Runners 优秀女性越野跑运动员跟骨矿物质评估。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101555
Javier Espasa-Labrador , John O. Osborne , Álex Cebrián-Ponce , Silvia Puigarnau , Toni Planas , Quim Rosales , Amigó, Alfredo Irurtia , Marta Carrasco-Marginet
This study aimed to assess the calcaneal bone mineral density (BMD) of elite female trail runners and evaluate its reliability using a novel DXA method. It also examined the relationship between calcaneal BMD and other regions of interest to better understand bone health in this specific population. A cross-sectional study was conducted with 35 elite female trail runners from the Spanish national team. BMD was measured at six anatomical regions using DXA, with particular focus on the calcaneus. Intra- and inter-rater reliability were evaluated using intraclass correlation coefficients (ICC). Descriptive statistics and correlations between calcaneal BMD and other anatomical sites, such as the lumbar spine and femoral neck, were analyzed. Calcaneal BMD showed excellent reliability (ICC = 0.95–0.98), confirming the robustness of the proposed measurement method. The mean calcaneal BMD (0.660 ± 0.105 g·cm²) was higher than that of non-athletes but lower than athletes from other endurance sports, such as road running. Significant correlations were found between calcaneal BMD and other regions, including the femoral neck (r = 0.58) and lumbar spine (r = 0.50), indicating that calcaneal BMD may provide complementary information for assessing bone health. The study confirms the reliability of calcaneal BMD measurement in elite female trail runners and highlights its potential as a useful complementary tool for monitoring bone health. Further longitudinal studies are needed to determine whether calcaneal BMD can serve as an indicator for stress fractures and other bone-related injuries in endurance athletes.
本研究旨在评估精英女子越野跑运动员的小腿骨矿物质密度 (BMD),并使用新型 DXA 方法评估其可靠性。研究还探讨了小腿骨 BMD 与其他相关区域之间的关系,以更好地了解这一特殊人群的骨骼健康状况。这项横断面研究的对象是来自西班牙国家队的 35 名精英女子越野跑运动员。使用 DXA 测量了六个解剖区域的 BMD,重点是小腿骨。使用类内相关系数(ICC)评估了评分者内部和评分者之间的可靠性。还分析了描述性统计数字以及小腿骨 BMD 与腰椎和股骨颈等其他解剖部位之间的相关性。小腿骨 BMD 显示出极佳的可靠性(ICC = 0.95-0.98),证实了拟议测量方法的稳健性。小腿骨 BMD 平均值(0.660 ± 0.105 g-cm²)高于非运动员,但低于路跑等其他耐力运动的运动员。研究发现,小腿骨 BMD 与其他部位(包括股骨颈(r = 0.58)和腰椎(r = 0.50))之间存在显著相关性,这表明小腿骨 BMD 可为评估骨骼健康提供补充信息。该研究证实了在精英女子越野跑运动员中测量小腿骨 BMD 的可靠性,并强调了其作为监测骨骼健康的有用补充工具的潜力。要确定小腿骨 BMD 是否可作为耐力运动员应力性骨折和其他骨相关损伤的指标,还需要进一步的纵向研究。
{"title":"Calcaneal Bone Mineral Assessment in Elite Female Trail Runners","authors":"Javier Espasa-Labrador ,&nbsp;John O. Osborne ,&nbsp;Álex Cebrián-Ponce ,&nbsp;Silvia Puigarnau ,&nbsp;Toni Planas ,&nbsp;Quim Rosales ,&nbsp;Amigó, Alfredo Irurtia ,&nbsp;Marta Carrasco-Marginet","doi":"10.1016/j.jocd.2024.101555","DOIUrl":"10.1016/j.jocd.2024.101555","url":null,"abstract":"<div><div>This study aimed to assess the calcaneal bone mineral density (BMD) of elite female trail runners and evaluate its reliability using a novel DXA method. It also examined the relationship between calcaneal BMD and other regions of interest to better understand bone health in this specific population. A cross-sectional study was conducted with 35 elite female trail runners from the Spanish national team. BMD was measured at six anatomical regions using DXA, with particular focus on the calcaneus. Intra- and inter-rater reliability were evaluated using intraclass correlation coefficients (ICC). Descriptive statistics and correlations between calcaneal BMD and other anatomical sites, such as the lumbar spine and femoral neck, were analyzed. Calcaneal BMD showed excellent reliability (ICC = 0.95–0.98), confirming the robustness of the proposed measurement method. The mean calcaneal BMD (0.660 ± 0.105 g·cm²) was higher than that of non-athletes but lower than athletes from other endurance sports, such as road running. Significant correlations were found between calcaneal BMD and other regions, including the femoral neck (r = 0.58) and lumbar spine (r = 0.50), indicating that calcaneal BMD may provide complementary information for assessing bone health. The study confirms the reliability of calcaneal BMD measurement in elite female trail runners and highlights its potential as a useful complementary tool for monitoring bone health. Further longitudinal studies are needed to determine whether calcaneal BMD can serve as an indicator for stress fractures and other bone-related injuries in endurance athletes.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101555"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Approach to Identify Forearm “Slot Error” 一种前臂“槽位误差”识别方法。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101557
G. Gottinger, N. Binkley, D. Krueger
{"title":"An Approach to Identify Forearm “Slot Error”","authors":"G. Gottinger,&nbsp;N. Binkley,&nbsp;D. Krueger","doi":"10.1016/j.jocd.2024.101557","DOIUrl":"10.1016/j.jocd.2024.101557","url":null,"abstract":"","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101557"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Traditional Chinese Medicine Kidney-Tonifying Methods on Osteoporosis or Bone Loss in HR+ Breast Cancer Patients Following Endocrine Therapy 中药补肾法对内分泌治疗后HR+乳腺癌患者骨质疏松或骨质流失的影响。
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-01-01 DOI: 10.1016/j.jocd.2024.101558
Jie Luo , Peng Jiang , Liming Xu
Objective: This study aims to systematically assess the therapeutic effects of Traditional Chinese Medicine (TCM) kidney-tonifying methods on osteoporosis in HR+ breast cancer patients after endocrine therapy, and to explore their clinical application value.
Methods: This systematic review and meta-analysis adhered to the PRISMA guidelines and aimed to evaluate the impact of TCM kidney-tonifying methods on osteoporosis in HR+ breast cancer patients after endocrine therapy. Literature searches were conducted through October 2024 in databases including CBM, CNKI, Wanfang Data, PubMed, Web of Science, Cochrane Central, VIP, and renowned TCM databases such as TCM Online. Randomized controlled trials reporting lumbar spine bone density, femoral neck bone density, osteocalcin levels, pain VAS scores, and drug safety were included. The Cochrane tool was used for quality assessment, and meta-analysis was performed using RevMan 5.3 and Stata software.
Results: This meta-analysis included 25 studies, covering 1795 patients. The combined results showed significant improvements in lumbar spine bone density (SMD = 0.98, 95 % CI: 0.52–1.44, P < 0.0001), femoral neck bone density (SMD = 0.73, 95 % CI: 0.35–1.10, P = 0.0001), and osteocalcin levels (SMD = 1.23, 95 % CI: 0.52–1.93, P = 0.0007) in patients treated with TCM kidney-tonifying methods compared to those in the control group. There was also a significant reduction in pain VAS scores (SMD = −1.14, 95 % CI:1.55 to −0.72, P < 0.00001). The safety data indicated no significant adverse reactions associated with the treatment.
Conclusion: TCM kidney-tonifying methods can significantly improve osteoporosis symptoms post-endocrine therapy in HR+ breast cancer patients, enhance bone density, and effectively reduce pain, demonstrating good safety and potential clinical value. Future research should further validate these findings through large-scale, multi-center randomized controlled trials to optimize treatment strategies.
目的:本研究旨在系统评价中医补肾方法对内分泌治疗后HR+乳腺癌患者骨质疏松症的治疗效果,探讨其临床应用价值。方法:本系统综述和荟萃分析遵循PRISMA指南,旨在评价中医补肾方法对内分泌治疗后HR+乳腺癌患者骨质疏松的影响。文献检索截止到2024年10月,检索数据库包括CBM、CNKI、万方数据、PubMed、Web of Science、Cochrane Central、VIP和知名中医数据库如TCM Online。纳入报告腰椎骨密度、股骨颈骨密度、骨钙素水平、疼痛VAS评分和药物安全性的随机对照试验。采用Cochrane工具进行质量评价,采用RevMan 5.3和Stata软件进行meta分析。结果:本荟萃分析纳入25项研究,涵盖1795例患者。综合结果显示腰椎骨密度明显改善(SMD = 0.98,95 % CI: 0.52-1.44, P )结论:中药补肾法可显著改善HR+乳腺癌患者内分泌治疗后骨质疏松症状,增强骨密度,有效减轻疼痛,具有较好的安全性和潜在的临床价值。未来的研究应通过大规模、多中心随机对照试验进一步验证这些发现,以优化治疗策略。
{"title":"The Impact of Traditional Chinese Medicine Kidney-Tonifying Methods on Osteoporosis or Bone Loss in HR+ Breast Cancer Patients Following Endocrine Therapy","authors":"Jie Luo ,&nbsp;Peng Jiang ,&nbsp;Liming Xu","doi":"10.1016/j.jocd.2024.101558","DOIUrl":"10.1016/j.jocd.2024.101558","url":null,"abstract":"<div><div><em>Objective:</em> This study aims to systematically assess the therapeutic effects of Traditional Chinese Medicine (TCM) kidney-tonifying methods on osteoporosis in HR+ breast cancer patients after endocrine therapy, and to explore their clinical application value.</div><div><em>Methods:</em> This systematic review and meta-analysis adhered to the PRISMA guidelines and aimed to evaluate the impact of TCM kidney-tonifying methods on osteoporosis in HR+ breast cancer patients after endocrine therapy. Literature searches were conducted through October 2024 in databases including CBM, CNKI, Wanfang Data, PubMed, Web of Science, Cochrane Central, VIP, and renowned TCM databases such as TCM Online. Randomized controlled trials reporting lumbar spine bone density, femoral neck bone density, osteocalcin levels, pain VAS scores, and drug safety were included. The Cochrane tool was used for quality assessment, and meta-analysis was performed using RevMan 5.3 and Stata software.</div><div><em>Results:</em> This meta-analysis included 25 studies, covering 1795 patients. The combined results showed significant improvements in lumbar spine bone density (SMD = 0.98, 95 % CI: 0.52–1.44, <em>P</em> &lt; 0.0001), femoral neck bone density (SMD = 0.73, 95 % CI: 0.35–1.10, <em>P</em> = 0.0001), and osteocalcin levels (SMD = 1.23, 95 % CI: 0.52–1.93, <em>P</em> = 0.0007) in patients treated with TCM kidney-tonifying methods compared to those in the control group. There was also a significant reduction in pain VAS scores (SMD = −1.14, 95 % CI:1.55 to −0.72, <em>P</em> &lt; 0.00001). The safety data indicated no significant adverse reactions associated with the treatment.</div><div><em>Conclusion:</em> TCM kidney-tonifying methods can significantly improve osteoporosis symptoms post-endocrine therapy in HR+ breast cancer patients, enhance bone density, and effectively reduce pain, demonstrating good safety and potential clinical value. Future research should further validate these findings through large-scale, multi-center randomized controlled trials to optimize treatment strategies.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101558"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Moving towards an equitable future: Rethinking the use of race in pediatric densitometry 迈向公平的未来:重新思考种族在儿科骨密度测量中的应用
IF 1.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-10-24 DOI: 10.1016/j.jocd.2024.101536
Amira Ramadan, Nessa Tantivit, Alicia Pendleton, Catherine M. Gordon, Robert H. Rosen, Nora E. Renthal
Current guidelines from the International Society for Clinical Densitometry (ISCD) recommend considering race, sex, and age in calculating pediatric bone density z-scores by Dual-Energy X-ray Absorptiometry (DXA). However, as patient populations become increasingly diverse, the application of these guidelines presents significant challenges, potentially leading to racial bias and systemic inequities in care. In response to growing calls for a reevaluation of race's role in clinical decision-making, we aimed to assess the readiness of front-line providers of DXA services to address these challenges. We conducted a professional, anonymized clinical practice survey targeting DXA technologists from various centers as part of a workshop for Reevaluation of the Role of Race, Ethnicity, and Ancestry in Clinical Decision-Making at the 2024 Annual Meeting of the Pediatric Academic Society. The survey focused on their experiences with the recording and use of race demographics. Our findings revealed inconsistencies in race data collection practices, varying levels of perceived patient comfort, and concerns about the potential perpetuation of racial bias. These results highlight the need for standardized guidelines to facilitate the sensitive and unbiased collection of race-related data during DXA exams, ultimately promoting equitable care for all patients.
国际临床骨密度测量学会(ISCD)的现行指南建议,在通过双能量 X 射线吸收测定法(DXA)计算儿科骨密度 z 值时,应考虑种族、性别和年龄因素。然而,随着患者群体的日益多样化,这些指南的应用面临着巨大的挑战,有可能导致护理中的种族偏见和系统性不公平。为了响应越来越多的呼吁,重新评估种族在临床决策中的作用,我们旨在评估一线 DXA 服务提供者应对这些挑战的准备情况。作为儿科学术学会 2024 年年会 "重新评估种族、民族和祖先在临床决策中的作用 "研讨会的一部分,我们针对来自不同中心的 DXA 技术人员进行了一项专业的匿名临床实践调查。调查的重点是他们在记录和使用种族人口统计数据方面的经验。我们的调查结果揭示了种族数据收集实践中的不一致性、患者感受到的舒适程度不同以及对种族偏见可能长期存在的担忧。这些结果突出表明,有必要制定标准化指南,以便在 DXA 检查过程中敏感、公正地收集种族相关数据,最终促进对所有患者的公平护理。
{"title":"Moving towards an equitable future: Rethinking the use of race in pediatric densitometry","authors":"Amira Ramadan,&nbsp;Nessa Tantivit,&nbsp;Alicia Pendleton,&nbsp;Catherine M. Gordon,&nbsp;Robert H. Rosen,&nbsp;Nora E. Renthal","doi":"10.1016/j.jocd.2024.101536","DOIUrl":"10.1016/j.jocd.2024.101536","url":null,"abstract":"<div><div>Current guidelines from the International Society for Clinical Densitometry (ISCD) recommend considering race, sex, and age in calculating pediatric bone density z-scores by Dual-Energy X-ray Absorptiometry (DXA). However, as patient populations become increasingly diverse, the application of these guidelines presents significant challenges, potentially leading to racial bias and systemic inequities in care. In response to growing calls for a reevaluation of race's role in clinical decision-making, we aimed to assess the readiness of front-line providers of DXA services to address these challenges. We conducted a professional, anonymized clinical practice survey targeting DXA technologists from various centers as part of a workshop for Reevaluation of the Role of Race, Ethnicity, and Ancestry in Clinical Decision-Making at the 2024 Annual Meeting of the Pediatric Academic Society. The survey focused on their experiences with the recording and use of race demographics. Our findings revealed inconsistencies in race data collection practices, varying levels of perceived patient comfort, and concerns about the potential perpetuation of racial bias. These results highlight the need for standardized guidelines to facilitate the sensitive and unbiased collection of race-related data during DXA exams, ultimately promoting equitable care for all patients.</div></div>","PeriodicalId":50240,"journal":{"name":"Journal of Clinical Densitometry","volume":"28 1","pages":"Article 101536"},"PeriodicalIF":1.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Clinical Densitometry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1