首页 > 最新文献

Explore-The Journal of Science and Healing最新文献

英文 中文
Effect assessment of traditional Chinese medicine, Guilu Erxian Jiao, in patients with osteoporosis: A case-control study of the Chang gung memorial hospital 中药桂枝二仙胶对骨质疏松症患者的疗效评估:长庚纪念医院病例对照研究
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-14 DOI: 10.1016/j.explore.2024.01.004
Yuan-Xin Lai , Chu-Yao Tseng , Huang-Yu Yang , Sien-Hung Yang , Pai-Wei Lee , Tsung-Hsien Yang

Background

Osteoporosis is a chronic skeletal disease characterized by low bone mass and increased risk of fracture. In Taiwan, Guilu Erxian Jiao (GEJ) is the commonly used formula of Chinese herbal medicines for patients with osteoporosis. However, the effect of GEJ on subsequent fractures in the long term is unclear. This is the first long-term case-control study of the effects of GEJ on the rates of fracture in patients with osteoporosis.

Methods

We collected data from January 1, 2000 to December 31, 2019 from the Chang Gung Research Database. We interpreted from the reports of DXA to confirm whether the patients met the criteria for osteoporosis (T score ≤ -2.5). Eighty-five patients were enrolled in the GEJ group. After two propensity score matchings, 425 patients were identified as the non-GEJ group. We assessed four outcomes to confirm the effects of GEJ in patients with osteoporosis, including the change in the T-score, new occurrences of fractures, cumulative rate of fracture, and how many doses of GEJ need to be administered to effectively reduce fractures

Results

There was no significant difference in either the improvement in the T score or the 5-year overall fracture (p = 0.335) between these two groups. At the fracture-prone sites, the fracture in lumbar vertebrae was less in the GEJ group (p = 0.034). A total of 600 GEJ pills are required to effectively reduce the incidence of fractures (p value= 0.0039).

Conclusions

Patients who take at least 600 GEJ pills would have a decreased fracture risk at fracture-prone sites.

背景骨质疏松症是一种慢性骨骼疾病,其特点是骨量低、骨折风险增加。在台湾,桂枝二仙胶(GEJ)是骨质疏松症患者常用的中药配方。然而,长期服用桂枝二仙胶对后续骨折的影响尚不明确。这是第一项关于葛仙椒对骨质疏松症患者骨折发生率影响的长期病例对照研究。我们从 DXA 报告中解读患者是否符合骨质疏松症的标准(T 评分≤-2.5)。85名患者被纳入GEJ组。经过两次倾向评分匹配后,425 名患者被确定为非 GEJ 组。我们评估了四项结果,以确认 GEJ 对骨质疏松症患者的疗效,包括 T 评分的变化、新发骨折、骨折累积率以及需要服用多少剂量的 GEJ 才能有效减少骨折的发生结果两组患者的 T 评分改善程度和 5 年总骨折率均无显著差异(P = 0.335)。在骨折易发部位,GEJ 组的腰椎骨折较少(p = 0.034)。结论服用至少 600 片 GEJ 药片的患者可降低骨折易发部位的骨折风险。
{"title":"Effect assessment of traditional Chinese medicine, Guilu Erxian Jiao, in patients with osteoporosis: A case-control study of the Chang gung memorial hospital","authors":"Yuan-Xin Lai ,&nbsp;Chu-Yao Tseng ,&nbsp;Huang-Yu Yang ,&nbsp;Sien-Hung Yang ,&nbsp;Pai-Wei Lee ,&nbsp;Tsung-Hsien Yang","doi":"10.1016/j.explore.2024.01.004","DOIUrl":"10.1016/j.explore.2024.01.004","url":null,"abstract":"<div><h3>Background</h3><p>Osteoporosis is a chronic skeletal disease characterized by low bone mass and increased risk of fracture. In Taiwan, Guilu Erxian Jiao (GEJ) is the commonly used formula of Chinese herbal medicines for patients with osteoporosis. However, the effect of GEJ on subsequent fractures in the long term is unclear. This is the first long-term case-control study of the effects of GEJ on the rates of fracture in patients with osteoporosis.</p></div><div><h3>Methods</h3><p>We collected data from January 1, 2000 to December 31, 2019 from the Chang Gung Research Database. We interpreted from the reports of DXA to confirm whether the patients met the criteria for osteoporosis (T score ≤ -2.5). Eighty-five patients were enrolled in the GEJ group. After two propensity score matchings, 425 patients were identified as the non-GEJ group. We assessed four outcomes to confirm the effects of GEJ in patients with osteoporosis, including the change in the T-score, new occurrences of fractures, cumulative rate of fracture, and how many doses of GEJ need to be administered to effectively reduce fractures</p></div><div><h3>Results</h3><p>There was no significant difference in either the improvement in the T score or the 5-year overall fracture (<em>p</em> = 0.335) between these two groups. At the fracture-prone sites, the fracture in lumbar vertebrae was less in the GEJ group (<em>p</em> = 0.034). A total of 600 GEJ pills are required to effectively reduce the incidence of fractures (p value= 0.0039).</p></div><div><h3>Conclusions</h3><p>Patients who take at least 600 GEJ pills would have a decreased fracture risk at fracture-prone sites.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alternative therapy for acute appendicitis with appendicolith using traditional Chinese medicine: A case report 急性阑尾炎伴阑尾结石的中医替代疗法:病例报告
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-13 DOI: 10.1016/j.explore.2024.01.003
Shih-Han Wang , Shi-Chen Ou , Ting-Yen Lin , Tung-Ti Chang

Introduction

Treating older patients with acute appendicitis with multiple underlying diseases is a challenging situation in the clinical setting. Throughout the history of East Asian medicine, many texts have noted the use of herbal decoctions to successfully treat symptoms associated with appendicitis, thereby providing an alternative management strategy for treating frail patients with acute appendicitis.

Case presentation

This report presents the case of a 93-year-old male diagnosed with acute appendicitis with appendicolith who was unsuitable for surgical intervention due to poor lung condition and prolonged prothrombin time caused by Apixaban. By receiving complementary therapy consisting of traditional Chinese medicine (TCM) and antibiotics, he recovered successfully.

Discussion

In the early stage of acute appendicitis, infection control and gastrointestinal mobility are the most important factors to consider. Scientific research has demonstrated that many herbs used in TCM formulas possess anti-inflammatory, anti-oxidative and immune attenuation effects. For many patients who are unsuitable for surgical intervention due to unfavorable conditions, such as the prolonged prothrombin time presented in this case, complementary treatment with TCM offers adjuvant therapeutical effects associated with infection control, and improvement of the gastrointestinal environment and function of elderly patients.

导言治疗患有急性阑尾炎并伴有多种基础疾病的老年患者在临床环境中是一种具有挑战性的情况。在东亚医学史上,许多典籍都记载了使用中药煎剂成功治疗阑尾炎相关症状的方法,从而为治疗体弱的急性阑尾炎患者提供了另一种治疗策略。本病例报告了一例被诊断为急性阑尾炎伴阑尾结石的 93 岁男性患者,由于肺部状况不佳以及阿哌沙班导致凝血酶原时间延长,他不适合手术治疗。讨论 在急性阑尾炎的早期阶段,控制感染和肠胃蠕动是最重要的考虑因素。科学研究表明,中药配方中使用的许多中草药都具有抗炎、抗氧化和免疫衰减作用。对于许多因不利条件(如本病例中凝血酶原时间延长)而不适合手术治疗的患者,中医药的辅助治疗具有控制感染、改善老年患者胃肠道环境和功能的辅助治疗作用。
{"title":"Alternative therapy for acute appendicitis with appendicolith using traditional Chinese medicine: A case report","authors":"Shih-Han Wang ,&nbsp;Shi-Chen Ou ,&nbsp;Ting-Yen Lin ,&nbsp;Tung-Ti Chang","doi":"10.1016/j.explore.2024.01.003","DOIUrl":"10.1016/j.explore.2024.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Treating older patients with acute appendicitis with multiple underlying diseases is a challenging situation in the clinical setting. Throughout the history of East Asian medicine, many texts have noted the use of herbal decoctions to successfully treat symptoms associated with appendicitis, thereby providing an alternative management strategy for treating frail patients with acute appendicitis.</p></div><div><h3>Case presentation</h3><p>This report presents the case of a 93-year-old male diagnosed with acute appendicitis with appendicolith who was unsuitable for surgical intervention due to poor lung condition and prolonged prothrombin time caused by Apixaban. By receiving complementary therapy consisting of traditional Chinese medicine (TCM) and antibiotics, he recovered successfully.</p></div><div><h3>Discussion</h3><p>In the early stage of acute appendicitis, infection control and gastrointestinal mobility are the most important factors to consider. Scientific research has demonstrated that many herbs used in TCM formulas possess anti-inflammatory, anti-oxidative and immune attenuation effects. For many patients who are unsuitable for surgical intervention due to unfavorable conditions, such as the prolonged prothrombin time presented in this case, complementary treatment with TCM offers adjuvant therapeutical effects associated with infection control, and improvement of the gastrointestinal environment and function of elderly patients.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139462262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring client's experiences of a new energy healing modality: Magdalena energy session(s) 探索客户对新能量疗法的体验:玛格达莱纳能量疗程
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-10 DOI: 10.1016/j.explore.2024.01.001
Angela U. Ekwonye, Alvina Brueggemann

Context

Anecdotal experience of Magdalena energy session(s) offers some indication of its health benefits, yet the literature on this new energy healing modality is scarce.

Objective

To explore the personal experience of recipients of the Magdalena energy session(s).

Method

In-depth interviews were conducted with 25 generally healthy volunteer adults from around the world who had received at least one Magdalena energy healing session with a certified Magdalena practitioner. Thematic analysis was used to discern patterns in the experience.

Results

Participants had different motives for attending the Magdalena energy session(s). Clients reported experiencing movement and release of energy, changes in sensation and feeling, and transcendental experience during the Magdalena energy session(s). After the session(s), there were reports of a sustained feeling of lightness, increased positive emotions, increased self-awareness, and deeper spiritual connection. Participants noted the uniqueness of the Magdalena energy session(s) compared to other energy healing practices.

Conclusion

The findings from this qualitative study suggest that Magdalena energy session(s) can elicit a relaxation response, alter emotions, and increase spiritual connections to facilitate a subjective healing experience. Therefore, the present study recommends further investigations to elucidate variables for a larger-scale intervention study of the effects of Magdalena energy session(s) on health outcomes and the underlying mechanisms of action.

背景马格达莱纳能量疗程的轶事经验在一定程度上说明了其对健康的益处,但有关这种新型能量疗程的文献却很少。方法对来自世界各地的 25 名身体健康的成年人志愿者进行了深入访谈,他们至少接受过一次马格达莱纳能量疗程,并获得了马格达莱纳从业者的认证。结果参与者参加马格达莱纳能量疗程的动机各不相同。客户报告说,在马格达莱纳能量疗程中,他们体验到了能量的运动和释放、感觉和感受的变化以及超凡体验。疗程结束后,有报告称他们持续感受到轻盈、积极情绪增加、自我意识增强以及心灵联系加深。结论:本定性研究的结果表明,马格达莱纳能量疗程可以引起放松反应、改变情绪、增强心灵联系,从而促进主观疗愈体验。因此,本研究建议开展进一步调查,以阐明各种变量,从而就马格达莱纳能量疗程对健康结果的影响及其作用机制开展更大规模的干预研究。
{"title":"Exploring client's experiences of a new energy healing modality: Magdalena energy session(s)","authors":"Angela U. Ekwonye,&nbsp;Alvina Brueggemann","doi":"10.1016/j.explore.2024.01.001","DOIUrl":"10.1016/j.explore.2024.01.001","url":null,"abstract":"<div><h3>Context</h3><p>Anecdotal experience of Magdalena energy session(s) offers some indication of its health benefits, yet the literature on this new energy healing modality is scarce.</p></div><div><h3>Objective</h3><p>To explore the personal experience of recipients of the Magdalena energy session(s).</p></div><div><h3>Method</h3><p>In-depth interviews were conducted with 25 generally healthy volunteer adults from around the world who had received at least one Magdalena energy healing session with a certified Magdalena practitioner. Thematic analysis was used to discern patterns in the experience.</p></div><div><h3>Results</h3><p>Participants had different motives for attending the Magdalena energy session(s). Clients reported experiencing movement and release of energy, changes in sensation and feeling, and transcendental experience during the Magdalena energy session(s). After the session(s), there were reports of a sustained feeling of lightness, increased positive emotions, increased self-awareness, and deeper spiritual connection. Participants noted the uniqueness of the Magdalena energy session(s) compared to other energy healing practices.</p></div><div><h3>Conclusion</h3><p>The findings from this qualitative study suggest that Magdalena energy session(s) can elicit a relaxation response, alter emotions, and increase spiritual connections to facilitate a subjective healing experience. Therefore, the present study recommends further investigations to elucidate variables for a larger-scale intervention study of the effects of Magdalena energy session(s) on health outcomes and the underlying mechanisms of action.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000016/pdfft?md5=2b6505c1c6385d22a5828006ced75f89&pid=1-s2.0-S1550830724000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139421146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing the effects of rosemary aromatherapy and music therapy on anxiety levels in patients undergoing general surgery: A randomized controlled clinical trial 比较迷迭香芳香疗法和音乐疗法对普外科手术患者焦虑水平的影响:随机对照临床试验
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-09 DOI: 10.1016/j.explore.2024.01.002
Mandana Sayadi Mank-halati , Mansour Rezaei , Mohammad Hussein Farzaei , Alireza Khatony

Background

Preoperative anxiety is a prevalent concern among patients undergoing surgery, potentially elevating the risk of postoperative complications. This study aimed to compare the effectiveness of inhalation aromatherapy using rosemary essential oil and music therapy in reducing anxiety levels among general surgery patients.

Methods

This study employed a randomized controlled clinical trial design involving 236 patients scheduled for general surgery. The participants were randomly assigned to one of four groups: aromatherapy with Rosmarinus officinalis L. essential oil (n = 59), music therapy (n = 59), combined aromatherapy and music therapy (n = 59), and a control group (n = 59). Data collection instruments consisted of the Spielberger State Anxiety Inventory, a personal information form, a music player, and wireless headphones. In the aromatherapy group, patients were instructed to inhale three drops of 25% rosemary essential oil. The music therapy group listened to instrumental music through headphones, while the combined group received both inhalation aromatherapy with rosemary essential oil and music therapy. The control group received three drops of an aromatic placebo. The interventions were administered for a duration of 30 min, starting one hour before surgery. Inferential statistics, including the Kolmogorov-Smirnov test, chi-square test, paired t-test, one-way analysis of variance, and LSD post-hoc test, were employed for data analysis.

Results

The study findings demonstrated significant effectiveness in reducing anxiety among surgical patients for aromatherapy (P = 0.001), music therapy (P < 0.001), and combined aromatherapy and music therapy (P = 0.001). Aromatherapy showed the highest anxiety-reducing effect, whereas combined therapy exhibited the lowest effect.

Conclusion

The results indicate that inhalation aromatherapy, music therapy, and combined aromatherapy and music therapy are all effective approaches for anxiety reduction in surgical patients. Hence, the implementation of these cost-effective and non-invasive interventions is recommended to alleviate anxiety among surgical patients.

背景术前焦虑是接受手术的患者普遍关心的问题,可能会增加术后并发症的风险。本研究旨在比较使用迷迭香精油的吸入式芳香疗法和音乐疗法在降低普外科患者焦虑水平方面的效果。方法本研究采用随机对照临床试验设计,涉及 236 名计划接受普外科手术的患者。参与者被随机分配到四组中的一组:迷迭香精油芳香疗法组(59 人)、音乐疗法组(59 人)、芳香疗法和音乐疗法联合组(59 人)以及对照组(59 人)。数据收集工具包括斯皮尔伯格状态焦虑量表、个人信息表、音乐播放器和无线耳机。芳香疗法组指导患者吸入三滴 25% 的迷迭香精油。音乐治疗组通过耳机聆听器乐,而综合组则同时接受迷迭香精油吸入芳香疗法和音乐治疗。对照组则滴入三滴芳香安慰剂。干预时间为 30 分钟,从手术前一小时开始。研究结果表明,芳香疗法(P=0.001)、音乐疗法(P<0.001)以及联合芳香疗法和音乐疗法(P=0.001)均能显著降低手术患者的焦虑。结果表明,吸入式芳香疗法、音乐疗法以及芳香疗法和音乐疗法联合疗法都是减轻手术患者焦虑的有效方法。因此,建议采用这些具有成本效益的非侵入性干预措施来减轻手术患者的焦虑。
{"title":"Comparing the effects of rosemary aromatherapy and music therapy on anxiety levels in patients undergoing general surgery: A randomized controlled clinical trial","authors":"Mandana Sayadi Mank-halati ,&nbsp;Mansour Rezaei ,&nbsp;Mohammad Hussein Farzaei ,&nbsp;Alireza Khatony","doi":"10.1016/j.explore.2024.01.002","DOIUrl":"10.1016/j.explore.2024.01.002","url":null,"abstract":"<div><h3>Background</h3><p>Preoperative anxiety is a prevalent concern among patients undergoing surgery, potentially elevating the risk of postoperative complications. This study aimed to compare the effectiveness of inhalation aromatherapy using rosemary essential oil and music therapy in reducing anxiety levels among general surgery patients.</p></div><div><h3>Methods</h3><p>This study employed a randomized controlled clinical trial design involving 236 patients scheduled for general surgery. The participants were randomly assigned to one of four groups: aromatherapy with Rosmarinus officinalis L. essential oil (<em>n</em> = 59), music therapy (<em>n</em> = 59), combined aromatherapy and music therapy (<em>n</em> = 59), and a control group (<em>n</em> = 59). Data collection instruments consisted of the Spielberger State Anxiety Inventory, a personal information form, a music player, and wireless headphones. In the aromatherapy group, patients were instructed to inhale three drops of 25% rosemary essential oil. The music therapy group listened to instrumental music through headphones, while the combined group received both inhalation aromatherapy with rosemary essential oil and music therapy. The control group received three drops of an aromatic placebo. The interventions were administered for a duration of 30 min, starting one hour before surgery. Inferential statistics, including the Kolmogorov-Smirnov test, chi-square test, paired <em>t</em>-test, one-way analysis of variance, and LSD post-hoc test, were employed for data analysis.</p></div><div><h3>Results</h3><p>The study findings demonstrated significant effectiveness in reducing anxiety among surgical patients for aromatherapy (<em>P</em> = 0.001), music therapy (<em>P</em> &lt; 0.001), and combined aromatherapy and music therapy (<em>P</em> = 0.001). Aromatherapy showed the highest anxiety-reducing effect, whereas combined therapy exhibited the lowest effect.</p></div><div><h3>Conclusion</h3><p>The results indicate that inhalation aromatherapy, music therapy, and combined aromatherapy and music therapy are all effective approaches for anxiety reduction in surgical patients. Hence, the implementation of these cost-effective and non-invasive interventions is recommended to alleviate anxiety among surgical patients.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139421013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Melatonin, vitamins and minerals supplements for the treatment of Covid-19 and Covid-like illness: A prospective, randomized, double-blind multicenter study 褪黑素、维生素和矿物质补充剂用于治疗 Covid-19 和 Covid 类疾病:一项前瞻性、随机、双盲多中心研究。
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2023.06.009
Lobna Mahjoub , Rym Youssef , Hajer Yaakoubi , Houda Ben Salah , Rahma Jaballah , Moez Mejri , Adel Sekma , Imen Trabelsi , Semir Nouira , Mariem Khrouf , Houda Ben Soltane , Zied Mezgar , Lotfi Boukadida , Asma Zorgati , Riadh Boukef

Background

Melatonin, zinc, and multivitamins are among most recommended supplements in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy and safety of this association in the treatment of COVID-19 and COVID-like illnesses.

Methods

We conducted a multicenter prospective, randomized, double-blind, controlled trial. Patients with no medical history consulting the emergency department for covid and covid-like illness and who were not hospitalized were included. Patients were assigned in a 1:1 ratio to the treatment or the placebo group. The primary outcome was studying the effectiveness of zinc multivitamin supplement and melatonin in the treatment of COVID and -like illnesses symptoms’ according to the time from randomization to clinical improvement. The pre-specified secondary outcomes were date of disappearance of symptoms present on admission, appearance of an adverse effect due to the administration of the treatment, number of patients developing complications, requiring hospitalization, requiring respiratory support.

Results

One hundred sixty four patients were eligible for the study and were randomized to either the treatment group or the placebo group. Overall, 128 of the 164 patients had a PCR for SARS-CoV-2, yielding a positive PCR result in 49.1% of them. Regarding the disappearance of all initial presenting symptoms: on the 5th day of the follow-up, there was a significant difference between the two groups with a p value 0.04;On the 10th day, there was a significant difference too with p value of 0.038. There were no significant differences between the two groups in recovery during the 15th day of follow-up p>0.5. Finally, 100% of patients fully recovered in the treatment group vs 98.8% in the placebo group. No severe adverse events were reported throughout the trial.

Conclusions

Our results showed that daily doses of Melatonin, zinc and vitamins did significantly reduce the duration of symptoms accelerating its disappearance among patients consulting with COVID-19 or COVID-19 like illness.

背景:褪黑素、锌和多种维生素是抗击冠状病毒病2019(COVID-19)最推荐的补充剂之一。我们的目的是研究这种联合疗法在治疗 COVID-19 和 COVID 类疾病中的有效性和安全性:我们进行了一项多中心前瞻性、随机、双盲对照试验。研究对象包括因柯威德和柯威德样疾病到急诊科就诊的无病史且未住院的患者。患者按 1:1 的比例被分配到治疗组或安慰剂组。主要结果是研究多种维生素锌补充剂和褪黑素在治疗 "COVID和类COVID疾病症状 "中的有效性,根据从随机分配到临床改善的时间。预设的次要结果是入院时症状消失的日期、治疗过程中出现的不良反应、出现并发症、需要住院、需要呼吸支持的患者人数:164 名患者符合研究条件,并被随机分配到治疗组或安慰剂组。总体而言,164 名患者中有 128 人进行了 SARS-CoV-2 PCR 检测,其中 49.1%的患者 PCR 检测结果呈阳性。关于最初出现的所有症状的消失情况:在随访的第 5 天,两组之间有显著差异,P 值为 0.04;在第 10 天,两组之间也有显著差异,P 值为 0.038。两组患者在随访第 15 天的恢复情况无明显差异,P>0.5。最后,治疗组 100%的患者完全康复,而安慰剂组为 98.8%。整个试验期间未出现严重不良反应:我们的研究结果表明,每日服用褪黑素、锌和维生素可明显缩短 COVID-19 或类似 COVID-19 疾病患者的症状持续时间,加速症状消失。
{"title":"Melatonin, vitamins and minerals supplements for the treatment of Covid-19 and Covid-like illness: A prospective, randomized, double-blind multicenter study","authors":"Lobna Mahjoub ,&nbsp;Rym Youssef ,&nbsp;Hajer Yaakoubi ,&nbsp;Houda Ben Salah ,&nbsp;Rahma Jaballah ,&nbsp;Moez Mejri ,&nbsp;Adel Sekma ,&nbsp;Imen Trabelsi ,&nbsp;Semir Nouira ,&nbsp;Mariem Khrouf ,&nbsp;Houda Ben Soltane ,&nbsp;Zied Mezgar ,&nbsp;Lotfi Boukadida ,&nbsp;Asma Zorgati ,&nbsp;Riadh Boukef","doi":"10.1016/j.explore.2023.06.009","DOIUrl":"10.1016/j.explore.2023.06.009","url":null,"abstract":"<div><h3>Background</h3><p>Melatonin, zinc, and multivitamins are among most recommended supplements in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy and safety of this association in the treatment of COVID-19 and COVID-like illnesses.</p></div><div><h3>Methods</h3><p>We conducted a multicenter prospective, randomized, double-blind, controlled trial. Patients with no medical history consulting the emergency department for covid and covid-like illness and who were not hospitalized were included. Patients were assigned in a 1:1 ratio to the treatment or the placebo group. The primary outcome was studying the effectiveness of zinc multivitamin supplement and melatonin in the treatment of COVID and -like illnesses symptoms’ according to the time from randomization to clinical improvement. The pre-specified secondary outcomes were date of disappearance of symptoms present on admission, appearance of an adverse effect due to the administration of the treatment, number of patients developing complications, requiring hospitalization, requiring respiratory support.</p></div><div><h3>Results</h3><p>One hundred sixty four patients were eligible for the study and were randomized to either the treatment group or the placebo group. Overall, 128 of the 164 patients had a PCR for SARS-CoV-2, yielding a positive PCR result in 49.1% of them. Regarding the disappearance of all initial presenting symptoms: on the <sup>5th</sup> day of the follow-up, there was a significant difference between the two groups with a p value 0.04;On the 10th day, there was a significant difference too with p value of 0.038. There were no significant differences between the two groups in recovery during the 15th day of follow-up p&gt;0.5. Finally, 100% of patients fully recovered in the treatment group vs 98.8% in the placebo group. No severe adverse events were reported throughout the trial.</p></div><div><h3>Conclusions</h3><p>Our results showed that daily doses of Melatonin, zinc and vitamins did significantly reduce the duration of symptoms accelerating its disappearance among patients consulting with COVID-19 or COVID-19 like illness.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9763693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of a lavender essential oil and sleep hygiene protocol on insomnia in postmenopausal women: A pilot randomized clinical trial✰✰✰ 薰衣草精油和睡眠卫生方案对绝经后妇女失眠的影响:随机临床试验
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2023.07.004
Leandro Lucena , Jair Guilherme Santos-Junior , Sergio Tufik , Helena Hachul

Introduction

Insomnia and vasomotor symptoms are frequently experienced during the menopausal transition and in postmenopause, worsening sleep maintenance and quality of life. Our study evaluated the use of lavender essential oil and sleep hygiene guidance on quality of life, sleep patterns and self-reported hot flashes in postmenopausal women with insomnia diagnosis.

Methods

This study is part of a larger experimental, double-blind, randomized controlled trial. We included 35 postmenopausal women with a diagnosis of insomnia who were distributed in two groups: A Placebo group (sunflower oil) and an Aroma group (Lavandula angustifolia essential oil); both inhaled the oils before bedtime for 29 days. The groups received sleep hygiene guidelines and weekly follow-up. Validated questionnaires were used to assess the effect of the intervention, and a sleep diary was used to assess sleep onset latency (SOL), total sleep time (TST), and sleep efficiency (SE) daily. Participants who complained of vasomotor symptoms at baseline kept a daily record of their frequency and intensity.

Results

All participants benefited in almost all domains of quality of life and in the self-assessed TST and SE. The Aroma group achieved a significant improvement in their overall quality of life score over time. No differences were observed in respect of the hot flashes record and daytime sleepiness.

Conclusions

The aromatherapy intervention was effective in improving the overall quality of life in the Aroma group. Moreover, the sleep diary and sleep hygiene instructions helped all participants to, respectively, self-assess and improve their sleep patterns.

简介在绝经过渡期和绝经后,失眠和血管运动症状经常出现,导致睡眠质量和生活质量下降。我们的研究评估了使用薰衣草精油和睡眠卫生指导对确诊失眠的绝经后妇女的生活质量、睡眠模式和自我报告潮热的影响:本研究是一项大型双盲随机对照实验的一部分。我们将 35 名确诊失眠的绝经后妇女分为两组:安慰剂组(葵花籽油)和芳香组(薰衣草精油);两组均在睡前吸入精油,为期 29 天。两组均接受睡眠卫生指南和每周随访。采用经过验证的问卷来评估干预效果,并使用睡眠日记来评估每天的睡眠开始潜伏期(SOL)、总睡眠时间(TST)和睡眠效率(SE)。基线时抱怨有血管运动症状的参与者则每天记录症状的频率和强度:结果:所有参与者在几乎所有的生活质量领域以及自我评估的 TST 和 SE 方面都获益匪浅。随着时间的推移,芳香组的总体生活质量得分显著提高。在潮热记录和白天嗜睡方面没有观察到差异:结论:芳香疗法干预能有效改善芳香组的整体生活质量。此外,睡眠日记和睡眠卫生指导分别帮助所有参与者自我评估和改善了他们的睡眠模式。
{"title":"Effect of a lavender essential oil and sleep hygiene protocol on insomnia in postmenopausal women: A pilot randomized clinical trial✰✰✰","authors":"Leandro Lucena ,&nbsp;Jair Guilherme Santos-Junior ,&nbsp;Sergio Tufik ,&nbsp;Helena Hachul","doi":"10.1016/j.explore.2023.07.004","DOIUrl":"10.1016/j.explore.2023.07.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Insomnia and vasomotor symptoms are frequently experienced during the menopausal transition and in postmenopause, worsening sleep maintenance and quality of life. Our study evaluated the use of lavender essential oil and sleep hygiene guidance on quality of life, sleep patterns and self-reported hot flashes in postmenopausal women with insomnia diagnosis.</p></div><div><h3>Methods</h3><p>This study is part of a larger experimental, double-blind, randomized controlled trial. We included 35 postmenopausal women with a diagnosis of insomnia who were distributed in two groups: A Placebo group (sunflower oil) and an Aroma group (<em>Lavandula angustifolia</em> essential oil); both inhaled the oils before bedtime for 29 days. The groups received sleep hygiene guidelines and weekly follow-up. Validated questionnaires were used to assess the effect of the intervention, and a sleep diary was used to assess sleep onset latency (SOL), total sleep time (TST), and sleep efficiency (SE) daily. Participants who complained of vasomotor symptoms at baseline kept a daily record of their frequency and intensity.</p></div><div><h3>Results</h3><p>All participants benefited in almost all domains of quality of life and in the self-assessed TST and SE. The Aroma group achieved a significant improvement in their overall quality of life score over time. No differences were observed in respect of the hot flashes record and daytime sleepiness.</p></div><div><h3>Conclusions</h3><p>The aromatherapy intervention was effective in improving the overall quality of life in the Aroma group. Moreover, the sleep diary and sleep hygiene instructions helped all participants to, respectively, self-assess and improve their sleep patterns.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of position change and abdominal massage on anxiety, pain and distension after colonoscopy: A randomized clinical trial 改变体位和腹部按摩对结肠镜检查后焦虑、疼痛和腹胀的影响:随机临床试验。
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2023.06.007
Senan Mutlu , Emel Yılmaz , Semra Tutcu Şahin

Context

Pain, abdominal distention, and anxiety are major risk factors encountered after colonoscopy. Complementary and alternative treatments, such as abdominal massage and position change, are used to reduce the associated risk factors.

Objective

To determine the effect of position change and abdominal massage on anxiety, pain, and distension after colonoscopy.

Design

A randomized three-group experimental trial.

Setting and Participants

This study was conducted with 123 patients who underwent colonoscopy at the endoscopy unit of a hospital located in western Turkey.

Methods

Three groups were formed: two interventional (abdominal massage and position change) and one control, each including 41 patients. Data were gathered using a personal information form, pre- and post-colonoscopy measurement form, the Visual Analog Scale (VAS), and the Spielberger State-Trait Anxiety Inventory. Pain and comfort levels, abdominal circumference values, and vital signs of the patients were measured at four evaluation times.

Results

In the abdominal massage group, the VAS pain scores and abdominal circumference measurements decreased the most and the VAS comfort scores increased the most 15 min after the patients were taken to the recovery room (p<0.05). Furthermore, bowel sounds were heard, and bloating was relieved in all patients in both intervention groups 15 min after they were taken to the recovery room.

Conclusions

Abdominal massage and position change can be considered effective interventions for relieving bloating and facilitating flatulence after colonoscopy. Moreover, abdominal massage can be a powerful method for reducing pain and abdominal circumference and increasing patient comfort.

背景:疼痛、腹胀和焦虑是结肠镜检查后遇到的主要风险因素。腹部按摩和体位改变等辅助和替代治疗可用于减少相关风险因素:确定体位改变和腹部按摩对结肠镜检查后焦虑、疼痛和腹胀的影响:设计:随机三组实验:本研究在土耳其西部一家医院的内窥镜室对 123 名接受结肠镜检查的患者进行了调查:分为三组:两组为干预组(腹部按摩和体位改变),一组为对照组,每组包括 41 名患者。使用个人信息表、结肠镜检查前后测量表、视觉模拟量表(VAS)和斯皮尔伯格状态-特质焦虑量表收集数据。在四个评估时间测量了患者的疼痛和舒适程度、腹围值和生命体征:结果:在腹部按摩组,患者被送往恢复室 15 分钟后,VAS 疼痛评分和腹围测量值下降幅度最大,VAS 舒适度评分上升幅度最大(p 结论:腹部按摩和体位改变可以减轻患者的疼痛,提高患者的舒适度:腹部按摩和体位改变可视为缓解结肠镜检查后腹胀和促进排气的有效干预措施。此外,腹部按摩也是减轻疼痛和腹围、提高患者舒适度的有效方法。
{"title":"The effect of position change and abdominal massage on anxiety, pain and distension after colonoscopy: A randomized clinical trial","authors":"Senan Mutlu ,&nbsp;Emel Yılmaz ,&nbsp;Semra Tutcu Şahin","doi":"10.1016/j.explore.2023.06.007","DOIUrl":"10.1016/j.explore.2023.06.007","url":null,"abstract":"<div><h3>Context</h3><p>Pain, abdominal distention, and anxiety are major risk factors encountered after colonoscopy. Complementary and alternative treatments, such as abdominal massage and position change, are used to reduce the associated risk factors.</p></div><div><h3>Objective</h3><p>To determine the effect of position change and abdominal massage on anxiety, pain, and distension after colonoscopy.</p></div><div><h3>Design</h3><p>A randomized three-group experimental trial.</p></div><div><h3>Setting and Participants</h3><p>This study was conducted with 123 patients who underwent colonoscopy at the endoscopy unit of a hospital located in western Turkey.</p></div><div><h3>Methods</h3><p>Three groups were formed: two interventional (abdominal massage and position change) and one control, each including 41 patients. Data were gathered using a personal information form, pre- and post-colonoscopy measurement form, the Visual Analog Scale (VAS), and the Spielberger State-Trait Anxiety Inventory. Pain and comfort levels, abdominal circumference values, and vital signs of the patients were measured at four evaluation times.</p></div><div><h3>Results</h3><p>In the abdominal massage group, the VAS pain scores and abdominal circumference measurements decreased the most and the VAS comfort scores increased the most 15 min after the patients were taken to the recovery room (<em>p</em>&lt;0.05). Furthermore, bowel sounds were heard, and bloating was relieved in all patients in both intervention groups 15 min after they were taken to the recovery room.</p></div><div><h3>Conclusions</h3><p>Abdominal massage and position change can be considered effective interventions for relieving bloating and facilitating flatulence after colonoscopy. Moreover, abdominal massage can be a powerful method for reducing pain and abdominal circumference and increasing patient comfort.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9718665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of acupressure application on patients’ nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy: A randomized placebo-controlled study 穴位按摩对腹腔镜胆囊切除术后患者恶心、呕吐、疼痛和睡眠质量的影响:随机安慰剂对照研究。
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2022.11.004
Tülay KILINÇ , Zeynep KARAMAN ÖZLÜ

Background and objectives

Nausea, vomiting, pain and insomnia in the postoperative period may cause discomfort, and this may adversely affect the patient's compliance with the treatment. This study was conducted to determine the effect of acupressure on nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy.

Methods

This was a randomized controlled experimental study with a placebo group. The sample comprised 188 patients who underwent laparoscopic cholecystectomy (control:64;experimental:64;and placebo:60). Acupressure was performed on the experimental and placebo groups with a wristband for 24 hours. The data were collected at the 0th, 2nd, 6th, 12th, and 24th postoperative hours. Data were collected using the patient introduction form, numeric nausea scale, visual analog scale(VAS), verbal category scale(VCS), and Richards-campbell sleep questionnaire(RCSQ).

Result

The difference between the mean scores of nausea severity and the presence of nausea at the postoperative 0–2, 2–6, and 12–24 hours was statistically significant between the groups and the presence and the severity of nausea was lower in the experimental group (p<0.05). Although not statistically significant, less vomiting was observed in the experimental group patients compared to the control group patients at postoperative 0–2, 2–6, and 12–24 hours. There was no significant difference between the mean VAS and VCS scores of the groups at postoperative 2nd, 6th, and 24th hours (p >0.05). The mean RCSQ total scores of the patients in the experimental group were significantly higher (p<0.001).

Conclusion

Acupressure applied to the PC6 point after laparoscopic cholecystectomy reduced postoperative nausea and vomiting and positively affected sleep quality.

背景和目的:术后恶心、呕吐、疼痛和失眠可能会引起不适,这可能会对患者的治疗依从性产生不利影响。本研究旨在确定穴位按摩对腹腔镜胆囊切除术后恶心、呕吐、疼痛和睡眠质量的影响:方法:这是一项随机对照实验研究,设有安慰剂组。样本包括188名接受腹腔镜胆囊切除术的患者(对照组:64人;实验组:64人;安慰剂组:60人)。实验组和安慰剂组均使用腕带进行 24 小时穴位按摩。在术后第 0、2、6、12 和 24 小时收集数据。数据收集采用了患者介绍表、恶心数字量表、视觉模拟量表(VAS)、言语类别量表(VCS)和理查兹-坎贝尔睡眠问卷(RCSQ):两组患者在术后 0-2、2-6 和 12-24 小时的恶心严重程度和出现恶心的平均得分差异有统计学意义,且实验组患者在术后 0-2、2-6 和 12-24 小时出现恶心的程度和严重程度较低(P>0.05)。实验组患者的平均 RCSQ 总分明显更高(P腹腔镜胆囊切除术后对PC6穴位进行穴位按摩可减轻术后恶心和呕吐,并对睡眠质量产生积极影响。
{"title":"Effect of acupressure application on patients’ nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy: A randomized placebo-controlled study","authors":"Tülay KILINÇ ,&nbsp;Zeynep KARAMAN ÖZLÜ","doi":"10.1016/j.explore.2022.11.004","DOIUrl":"10.1016/j.explore.2022.11.004","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Nausea, vomiting, pain and insomnia in the postoperative period may cause discomfort, and this may adversely affect the patient's compliance with the treatment. This study was conducted to determine the effect of acupressure on nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy.</p></div><div><h3>Methods</h3><p>This was a randomized controlled experimental study with a placebo group. The sample comprised 188 patients who underwent laparoscopic cholecystectomy (control:64;experimental:64;and placebo:60). Acupressure was performed on the experimental and placebo groups with a wristband for 24 hours. The data were collected at the 0th, 2nd, 6th, 12th, and 24th postoperative hours. Data were collected using the patient introduction form, numeric nausea scale, visual analog scale(VAS), verbal category scale(VCS), and Richards-campbell sleep questionnaire(RCSQ).</p></div><div><h3>Result</h3><p>The difference between the mean scores of nausea severity and the presence of nausea at the postoperative 0–2, 2–6, and 12–24 hours was statistically significant between the groups and the presence and the severity of nausea was lower in the experimental group (p&lt;0.05). Although not statistically significant, less vomiting was observed in the experimental group patients compared to the control group patients at postoperative 0–2, 2–6, and 12–24 hours. There was no significant difference between the mean VAS and VCS scores of the groups at postoperative 2<sup>nd</sup>, 6<sup>th</sup>, and 24<sup>th</sup> hours (p &gt;0.05). The mean RCSQ total scores of the patients in the experimental group were significantly higher (p&lt;0.001).</p></div><div><h3>Conclusion</h3><p>Acupressure applied to the PC6 point after laparoscopic cholecystectomy reduced postoperative nausea and vomiting and positively affected sleep quality.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10350256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of rose oil aromatherapy and hand-holding on pain due to peripheral intravenous catheter insertion 玫瑰精油芳香疗法和手部护理对外周静脉导管插入引起的疼痛的影响。
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2023.06.002
Tulay Basak, Ayla Demirtas, Senem Duman

Introduction

The study aimed to evaluate the effectiveness of rose oil (Rosa Damascene Mill.) aromatherapy and hand-holding in reducing pain associated with peripheral intravenous catheter insertion.

Methods

A comparative mixed-method design. A total of 126 patients were included in the study. For the study's quantitative data, sociodemographic characteristics of the patients and the Patient Interview Form for the qualitative data of the Numeric Rating Scale were used. In all patients included in the study, PIVC insertion was performed a single time by the same nurse using a standard procedure. Chi-square and Bonferroni tests were used for comparative statistics.

Results

No statistically significant difference between the groups regarding age, gender, marital status, BMI, and education level (p>0.05). Pain scores: it was 2.40±1.78 in the rose oil group, 3.53±1.98 in the hand-holding group, and 4.88±1.56 in the control group. The difference between the groups regarding pain scores is statistically significant (p=0.001).

Conclusions

The study determined that rose oil aromatherapy and hand-holding interventions reduce pain during PIVC. However, rose oil aromatherapy was more effective on pain than the hand-holding intervention.

(Clinical Trial ID: NCT05425849)

简介:该研究旨在评估玫瑰精油(Rosa Damascene Mill:本研究旨在评估玫瑰精油(Rosa Damascene Mill.)芳香疗法和手部护理对减轻外周静脉导管插入时疼痛的效果:方法:混合方法比较设计。研究共纳入了 126 名患者。在研究的定量数据中,使用了患者的社会人口学特征,在定性数据中,使用了《患者访谈表》中的数字评分量表。所有纳入研究的患者均由同一名护士按照标准程序一次性插入 PIVC。比较统计采用了卡方检验和Bonferroni检验:两组患者在年龄、性别、婚姻状况、体重指数和受教育程度方面差异无统计学意义(P>0.05)。疼痛评分:玫瑰精油组为(2.40±1.78)分,手握组为(3.53±1.98)分,对照组为(4.88±1.56)分。组间疼痛评分差异有统计学意义(P=0.001):研究结果表明,玫瑰精油芳香疗法和手拉手干预可以减轻 PIVC 期间的疼痛。然而,玫瑰精油芳香疗法比手握干预对疼痛更有效。(临床试验编号:NCT05425849)。
{"title":"The effect of rose oil aromatherapy and hand-holding on pain due to peripheral intravenous catheter insertion","authors":"Tulay Basak,&nbsp;Ayla Demirtas,&nbsp;Senem Duman","doi":"10.1016/j.explore.2023.06.002","DOIUrl":"10.1016/j.explore.2023.06.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The study aimed to evaluate the effectiveness of rose oil (Rosa Damascene Mill.) aromatherapy and hand-holding in reducing pain associated with peripheral intravenous catheter insertion.</p></div><div><h3>Methods</h3><p>A comparative mixed-method design. A total of 126 patients were included in the study. For the study's quantitative data, sociodemographic characteristics of the patients and the Patient Interview Form for the qualitative data of the Numeric Rating Scale were used. In all patients included in the study, PIVC insertion was performed a single time by the same nurse using a standard procedure. Chi-square and Bonferroni tests were used for comparative statistics.</p></div><div><h3>Results</h3><p>No statistically significant difference between the groups regarding age, gender, marital status, BMI, and education level (p&gt;0.05). Pain scores: it was 2.40±1.78 in the rose oil group, 3.53±1.98 in the hand-holding group, and 4.88±1.56 in the control group. The difference between the groups regarding pain scores is statistically significant (p=0.001).</p></div><div><h3>Conclusions</h3><p>The study determined that rose oil aromatherapy and hand-holding interventions reduce pain during PIVC. However, rose oil aromatherapy was more effective on pain than the hand-holding intervention.</p><p>(Clinical Trial ID: NCT05425849)</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9957080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Summary of a cochrane review: Dietary interventions for induction and maintenance of remission in inflammatory bowel disease 科克伦综述摘要:诱导和维持炎症性肠病缓解的饮食干预措施
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-01-01 DOI: 10.1016/j.explore.2023.12.012
Esra Mustafa
{"title":"Summary of a cochrane review: Dietary interventions for induction and maintenance of remission in inflammatory bowel disease","authors":"Esra Mustafa","doi":"10.1016/j.explore.2023.12.012","DOIUrl":"10.1016/j.explore.2023.12.012","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Explore-The Journal of Science and Healing
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1