Pub Date : 2024-01-14DOI: 10.1016/j.explore.2024.01.004
Yuan-Xin Lai , Chu-Yao Tseng , Huang-Yu Yang , Sien-Hung Yang , Pai-Wei Lee , Tsung-Hsien Yang
Background
Osteoporosis is a chronic skeletal disease characterized by low bone mass and increased risk of fracture. In Taiwan, Guilu Erxian Jiao (GEJ) is the commonly used formula of Chinese herbal medicines for patients with osteoporosis. However, the effect of GEJ on subsequent fractures in the long term is unclear. This is the first long-term case-control study of the effects of GEJ on the rates of fracture in patients with osteoporosis.
Methods
We collected data from January 1, 2000 to December 31, 2019 from the Chang Gung Research Database. We interpreted from the reports of DXA to confirm whether the patients met the criteria for osteoporosis (T score ≤ -2.5). Eighty-five patients were enrolled in the GEJ group. After two propensity score matchings, 425 patients were identified as the non-GEJ group. We assessed four outcomes to confirm the effects of GEJ in patients with osteoporosis, including the change in the T-score, new occurrences of fractures, cumulative rate of fracture, and how many doses of GEJ need to be administered to effectively reduce fractures
Results
There was no significant difference in either the improvement in the T score or the 5-year overall fracture (p = 0.335) between these two groups. At the fracture-prone sites, the fracture in lumbar vertebrae was less in the GEJ group (p = 0.034). A total of 600 GEJ pills are required to effectively reduce the incidence of fractures (p value= 0.0039).
Conclusions
Patients who take at least 600 GEJ pills would have a decreased fracture risk at fracture-prone sites.
背景骨质疏松症是一种慢性骨骼疾病,其特点是骨量低、骨折风险增加。在台湾,桂枝二仙胶(GEJ)是骨质疏松症患者常用的中药配方。然而,长期服用桂枝二仙胶对后续骨折的影响尚不明确。这是第一项关于葛仙椒对骨质疏松症患者骨折发生率影响的长期病例对照研究。我们从 DXA 报告中解读患者是否符合骨质疏松症的标准(T 评分≤-2.5)。85名患者被纳入GEJ组。经过两次倾向评分匹配后,425 名患者被确定为非 GEJ 组。我们评估了四项结果,以确认 GEJ 对骨质疏松症患者的疗效,包括 T 评分的变化、新发骨折、骨折累积率以及需要服用多少剂量的 GEJ 才能有效减少骨折的发生结果两组患者的 T 评分改善程度和 5 年总骨折率均无显著差异(P = 0.335)。在骨折易发部位,GEJ 组的腰椎骨折较少(p = 0.034)。结论服用至少 600 片 GEJ 药片的患者可降低骨折易发部位的骨折风险。
{"title":"Effect assessment of traditional Chinese medicine, Guilu Erxian Jiao, in patients with osteoporosis: A case-control study of the Chang gung memorial hospital","authors":"Yuan-Xin Lai , Chu-Yao Tseng , Huang-Yu Yang , Sien-Hung Yang , Pai-Wei Lee , Tsung-Hsien Yang","doi":"10.1016/j.explore.2024.01.004","DOIUrl":"10.1016/j.explore.2024.01.004","url":null,"abstract":"<div><h3>Background</h3><p>Osteoporosis is a chronic skeletal disease characterized by low bone mass and increased risk of fracture. In Taiwan, Guilu Erxian Jiao (GEJ) is the commonly used formula of Chinese herbal medicines for patients with osteoporosis. However, the effect of GEJ on subsequent fractures in the long term is unclear. This is the first long-term case-control study of the effects of GEJ on the rates of fracture in patients with osteoporosis.</p></div><div><h3>Methods</h3><p>We collected data from January 1, 2000 to December 31, 2019 from the Chang Gung Research Database. We interpreted from the reports of DXA to confirm whether the patients met the criteria for osteoporosis (T score ≤ -2.5). Eighty-five patients were enrolled in the GEJ group. After two propensity score matchings, 425 patients were identified as the non-GEJ group. We assessed four outcomes to confirm the effects of GEJ in patients with osteoporosis, including the change in the T-score, new occurrences of fractures, cumulative rate of fracture, and how many doses of GEJ need to be administered to effectively reduce fractures</p></div><div><h3>Results</h3><p>There was no significant difference in either the improvement in the T score or the 5-year overall fracture (<em>p</em> = 0.335) between these two groups. At the fracture-prone sites, the fracture in lumbar vertebrae was less in the GEJ group (<em>p</em> = 0.034). A total of 600 GEJ pills are required to effectively reduce the incidence of fractures (p value= 0.0039).</p></div><div><h3>Conclusions</h3><p>Patients who take at least 600 GEJ pills would have a decreased fracture risk at fracture-prone sites.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139538233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-13DOI: 10.1016/j.explore.2024.01.003
Shih-Han Wang , Shi-Chen Ou , Ting-Yen Lin , Tung-Ti Chang
Introduction
Treating older patients with acute appendicitis with multiple underlying diseases is a challenging situation in the clinical setting. Throughout the history of East Asian medicine, many texts have noted the use of herbal decoctions to successfully treat symptoms associated with appendicitis, thereby providing an alternative management strategy for treating frail patients with acute appendicitis.
Case presentation
This report presents the case of a 93-year-old male diagnosed with acute appendicitis with appendicolith who was unsuitable for surgical intervention due to poor lung condition and prolonged prothrombin time caused by Apixaban. By receiving complementary therapy consisting of traditional Chinese medicine (TCM) and antibiotics, he recovered successfully.
Discussion
In the early stage of acute appendicitis, infection control and gastrointestinal mobility are the most important factors to consider. Scientific research has demonstrated that many herbs used in TCM formulas possess anti-inflammatory, anti-oxidative and immune attenuation effects. For many patients who are unsuitable for surgical intervention due to unfavorable conditions, such as the prolonged prothrombin time presented in this case, complementary treatment with TCM offers adjuvant therapeutical effects associated with infection control, and improvement of the gastrointestinal environment and function of elderly patients.
{"title":"Alternative therapy for acute appendicitis with appendicolith using traditional Chinese medicine: A case report","authors":"Shih-Han Wang , Shi-Chen Ou , Ting-Yen Lin , Tung-Ti Chang","doi":"10.1016/j.explore.2024.01.003","DOIUrl":"10.1016/j.explore.2024.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Treating older patients with acute appendicitis with multiple underlying diseases is a challenging situation in the clinical setting. Throughout the history of East Asian medicine, many texts have noted the use of herbal decoctions to successfully treat symptoms associated with appendicitis, thereby providing an alternative management strategy for treating frail patients with acute appendicitis.</p></div><div><h3>Case presentation</h3><p>This report presents the case of a 93-year-old male diagnosed with acute appendicitis with appendicolith who was unsuitable for surgical intervention due to poor lung condition and prolonged prothrombin time caused by Apixaban. By receiving complementary therapy consisting of traditional Chinese medicine (TCM) and antibiotics, he recovered successfully.</p></div><div><h3>Discussion</h3><p>In the early stage of acute appendicitis, infection control and gastrointestinal mobility are the most important factors to consider. Scientific research has demonstrated that many herbs used in TCM formulas possess anti-inflammatory, anti-oxidative and immune attenuation effects. For many patients who are unsuitable for surgical intervention due to unfavorable conditions, such as the prolonged prothrombin time presented in this case, complementary treatment with TCM offers adjuvant therapeutical effects associated with infection control, and improvement of the gastrointestinal environment and function of elderly patients.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139462262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-10DOI: 10.1016/j.explore.2024.01.001
Angela U. Ekwonye, Alvina Brueggemann
Context
Anecdotal experience of Magdalena energy session(s) offers some indication of its health benefits, yet the literature on this new energy healing modality is scarce.
Objective
To explore the personal experience of recipients of the Magdalena energy session(s).
Method
In-depth interviews were conducted with 25 generally healthy volunteer adults from around the world who had received at least one Magdalena energy healing session with a certified Magdalena practitioner. Thematic analysis was used to discern patterns in the experience.
Results
Participants had different motives for attending the Magdalena energy session(s). Clients reported experiencing movement and release of energy, changes in sensation and feeling, and transcendental experience during the Magdalena energy session(s). After the session(s), there were reports of a sustained feeling of lightness, increased positive emotions, increased self-awareness, and deeper spiritual connection. Participants noted the uniqueness of the Magdalena energy session(s) compared to other energy healing practices.
Conclusion
The findings from this qualitative study suggest that Magdalena energy session(s) can elicit a relaxation response, alter emotions, and increase spiritual connections to facilitate a subjective healing experience. Therefore, the present study recommends further investigations to elucidate variables for a larger-scale intervention study of the effects of Magdalena energy session(s) on health outcomes and the underlying mechanisms of action.
{"title":"Exploring client's experiences of a new energy healing modality: Magdalena energy session(s)","authors":"Angela U. Ekwonye, Alvina Brueggemann","doi":"10.1016/j.explore.2024.01.001","DOIUrl":"10.1016/j.explore.2024.01.001","url":null,"abstract":"<div><h3>Context</h3><p>Anecdotal experience of Magdalena energy session(s) offers some indication of its health benefits, yet the literature on this new energy healing modality is scarce.</p></div><div><h3>Objective</h3><p>To explore the personal experience of recipients of the Magdalena energy session(s).</p></div><div><h3>Method</h3><p>In-depth interviews were conducted with 25 generally healthy volunteer adults from around the world who had received at least one Magdalena energy healing session with a certified Magdalena practitioner. Thematic analysis was used to discern patterns in the experience.</p></div><div><h3>Results</h3><p>Participants had different motives for attending the Magdalena energy session(s). Clients reported experiencing movement and release of energy, changes in sensation and feeling, and transcendental experience during the Magdalena energy session(s). After the session(s), there were reports of a sustained feeling of lightness, increased positive emotions, increased self-awareness, and deeper spiritual connection. Participants noted the uniqueness of the Magdalena energy session(s) compared to other energy healing practices.</p></div><div><h3>Conclusion</h3><p>The findings from this qualitative study suggest that Magdalena energy session(s) can elicit a relaxation response, alter emotions, and increase spiritual connections to facilitate a subjective healing experience. Therefore, the present study recommends further investigations to elucidate variables for a larger-scale intervention study of the effects of Magdalena energy session(s) on health outcomes and the underlying mechanisms of action.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1550830724000016/pdfft?md5=2b6505c1c6385d22a5828006ced75f89&pid=1-s2.0-S1550830724000016-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139421146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preoperative anxiety is a prevalent concern among patients undergoing surgery, potentially elevating the risk of postoperative complications. This study aimed to compare the effectiveness of inhalation aromatherapy using rosemary essential oil and music therapy in reducing anxiety levels among general surgery patients.
Methods
This study employed a randomized controlled clinical trial design involving 236 patients scheduled for general surgery. The participants were randomly assigned to one of four groups: aromatherapy with Rosmarinus officinalis L. essential oil (n = 59), music therapy (n = 59), combined aromatherapy and music therapy (n = 59), and a control group (n = 59). Data collection instruments consisted of the Spielberger State Anxiety Inventory, a personal information form, a music player, and wireless headphones. In the aromatherapy group, patients were instructed to inhale three drops of 25% rosemary essential oil. The music therapy group listened to instrumental music through headphones, while the combined group received both inhalation aromatherapy with rosemary essential oil and music therapy. The control group received three drops of an aromatic placebo. The interventions were administered for a duration of 30 min, starting one hour before surgery. Inferential statistics, including the Kolmogorov-Smirnov test, chi-square test, paired t-test, one-way analysis of variance, and LSD post-hoc test, were employed for data analysis.
Results
The study findings demonstrated significant effectiveness in reducing anxiety among surgical patients for aromatherapy (P = 0.001), music therapy (P < 0.001), and combined aromatherapy and music therapy (P = 0.001). Aromatherapy showed the highest anxiety-reducing effect, whereas combined therapy exhibited the lowest effect.
Conclusion
The results indicate that inhalation aromatherapy, music therapy, and combined aromatherapy and music therapy are all effective approaches for anxiety reduction in surgical patients. Hence, the implementation of these cost-effective and non-invasive interventions is recommended to alleviate anxiety among surgical patients.
{"title":"Comparing the effects of rosemary aromatherapy and music therapy on anxiety levels in patients undergoing general surgery: A randomized controlled clinical trial","authors":"Mandana Sayadi Mank-halati , Mansour Rezaei , Mohammad Hussein Farzaei , Alireza Khatony","doi":"10.1016/j.explore.2024.01.002","DOIUrl":"10.1016/j.explore.2024.01.002","url":null,"abstract":"<div><h3>Background</h3><p>Preoperative anxiety is a prevalent concern among patients undergoing surgery, potentially elevating the risk of postoperative complications. This study aimed to compare the effectiveness of inhalation aromatherapy using rosemary essential oil and music therapy in reducing anxiety levels among general surgery patients.</p></div><div><h3>Methods</h3><p>This study employed a randomized controlled clinical trial design involving 236 patients scheduled for general surgery. The participants were randomly assigned to one of four groups: aromatherapy with Rosmarinus officinalis L. essential oil (<em>n</em> = 59), music therapy (<em>n</em> = 59), combined aromatherapy and music therapy (<em>n</em> = 59), and a control group (<em>n</em> = 59). Data collection instruments consisted of the Spielberger State Anxiety Inventory, a personal information form, a music player, and wireless headphones. In the aromatherapy group, patients were instructed to inhale three drops of 25% rosemary essential oil. The music therapy group listened to instrumental music through headphones, while the combined group received both inhalation aromatherapy with rosemary essential oil and music therapy. The control group received three drops of an aromatic placebo. The interventions were administered for a duration of 30 min, starting one hour before surgery. Inferential statistics, including the Kolmogorov-Smirnov test, chi-square test, paired <em>t</em>-test, one-way analysis of variance, and LSD post-hoc test, were employed for data analysis.</p></div><div><h3>Results</h3><p>The study findings demonstrated significant effectiveness in reducing anxiety among surgical patients for aromatherapy (<em>P</em> = 0.001), music therapy (<em>P</em> < 0.001), and combined aromatherapy and music therapy (<em>P</em> = 0.001). Aromatherapy showed the highest anxiety-reducing effect, whereas combined therapy exhibited the lowest effect.</p></div><div><h3>Conclusion</h3><p>The results indicate that inhalation aromatherapy, music therapy, and combined aromatherapy and music therapy are all effective approaches for anxiety reduction in surgical patients. Hence, the implementation of these cost-effective and non-invasive interventions is recommended to alleviate anxiety among surgical patients.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139421013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melatonin, zinc, and multivitamins are among most recommended supplements in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy and safety of this association in the treatment of COVID-19 and COVID-like illnesses.
Methods
We conducted a multicenter prospective, randomized, double-blind, controlled trial. Patients with no medical history consulting the emergency department for covid and covid-like illness and who were not hospitalized were included. Patients were assigned in a 1:1 ratio to the treatment or the placebo group. The primary outcome was studying the effectiveness of zinc multivitamin supplement and melatonin in the treatment of COVID and -like illnesses symptoms’ according to the time from randomization to clinical improvement. The pre-specified secondary outcomes were date of disappearance of symptoms present on admission, appearance of an adverse effect due to the administration of the treatment, number of patients developing complications, requiring hospitalization, requiring respiratory support.
Results
One hundred sixty four patients were eligible for the study and were randomized to either the treatment group or the placebo group. Overall, 128 of the 164 patients had a PCR for SARS-CoV-2, yielding a positive PCR result in 49.1% of them. Regarding the disappearance of all initial presenting symptoms: on the 5th day of the follow-up, there was a significant difference between the two groups with a p value 0.04;On the 10th day, there was a significant difference too with p value of 0.038. There were no significant differences between the two groups in recovery during the 15th day of follow-up p>0.5. Finally, 100% of patients fully recovered in the treatment group vs 98.8% in the placebo group. No severe adverse events were reported throughout the trial.
Conclusions
Our results showed that daily doses of Melatonin, zinc and vitamins did significantly reduce the duration of symptoms accelerating its disappearance among patients consulting with COVID-19 or COVID-19 like illness.
{"title":"Melatonin, vitamins and minerals supplements for the treatment of Covid-19 and Covid-like illness: A prospective, randomized, double-blind multicenter study","authors":"Lobna Mahjoub , Rym Youssef , Hajer Yaakoubi , Houda Ben Salah , Rahma Jaballah , Moez Mejri , Adel Sekma , Imen Trabelsi , Semir Nouira , Mariem Khrouf , Houda Ben Soltane , Zied Mezgar , Lotfi Boukadida , Asma Zorgati , Riadh Boukef","doi":"10.1016/j.explore.2023.06.009","DOIUrl":"10.1016/j.explore.2023.06.009","url":null,"abstract":"<div><h3>Background</h3><p>Melatonin, zinc, and multivitamins are among most recommended supplements in the fight against coronavirus disease 2019 (COVID-19). We aimed to examine the efficacy and safety of this association in the treatment of COVID-19 and COVID-like illnesses.</p></div><div><h3>Methods</h3><p>We conducted a multicenter prospective, randomized, double-blind, controlled trial. Patients with no medical history consulting the emergency department for covid and covid-like illness and who were not hospitalized were included. Patients were assigned in a 1:1 ratio to the treatment or the placebo group. The primary outcome was studying the effectiveness of zinc multivitamin supplement and melatonin in the treatment of COVID and -like illnesses symptoms’ according to the time from randomization to clinical improvement. The pre-specified secondary outcomes were date of disappearance of symptoms present on admission, appearance of an adverse effect due to the administration of the treatment, number of patients developing complications, requiring hospitalization, requiring respiratory support.</p></div><div><h3>Results</h3><p>One hundred sixty four patients were eligible for the study and were randomized to either the treatment group or the placebo group. Overall, 128 of the 164 patients had a PCR for SARS-CoV-2, yielding a positive PCR result in 49.1% of them. Regarding the disappearance of all initial presenting symptoms: on the <sup>5th</sup> day of the follow-up, there was a significant difference between the two groups with a p value 0.04;On the 10th day, there was a significant difference too with p value of 0.038. There were no significant differences between the two groups in recovery during the 15th day of follow-up p>0.5. Finally, 100% of patients fully recovered in the treatment group vs 98.8% in the placebo group. No severe adverse events were reported throughout the trial.</p></div><div><h3>Conclusions</h3><p>Our results showed that daily doses of Melatonin, zinc and vitamins did significantly reduce the duration of symptoms accelerating its disappearance among patients consulting with COVID-19 or COVID-19 like illness.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9763693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Insomnia and vasomotor symptoms are frequently experienced during the menopausal transition and in postmenopause, worsening sleep maintenance and quality of life. Our study evaluated the use of lavender essential oil and sleep hygiene guidance on quality of life, sleep patterns and self-reported hot flashes in postmenopausal women with insomnia diagnosis.
Methods
This study is part of a larger experimental, double-blind, randomized controlled trial. We included 35 postmenopausal women with a diagnosis of insomnia who were distributed in two groups: A Placebo group (sunflower oil) and an Aroma group (Lavandula angustifolia essential oil); both inhaled the oils before bedtime for 29 days. The groups received sleep hygiene guidelines and weekly follow-up. Validated questionnaires were used to assess the effect of the intervention, and a sleep diary was used to assess sleep onset latency (SOL), total sleep time (TST), and sleep efficiency (SE) daily. Participants who complained of vasomotor symptoms at baseline kept a daily record of their frequency and intensity.
Results
All participants benefited in almost all domains of quality of life and in the self-assessed TST and SE. The Aroma group achieved a significant improvement in their overall quality of life score over time. No differences were observed in respect of the hot flashes record and daytime sleepiness.
Conclusions
The aromatherapy intervention was effective in improving the overall quality of life in the Aroma group. Moreover, the sleep diary and sleep hygiene instructions helped all participants to, respectively, self-assess and improve their sleep patterns.
简介在绝经过渡期和绝经后,失眠和血管运动症状经常出现,导致睡眠质量和生活质量下降。我们的研究评估了使用薰衣草精油和睡眠卫生指导对确诊失眠的绝经后妇女的生活质量、睡眠模式和自我报告潮热的影响:本研究是一项大型双盲随机对照实验的一部分。我们将 35 名确诊失眠的绝经后妇女分为两组:安慰剂组(葵花籽油)和芳香组(薰衣草精油);两组均在睡前吸入精油,为期 29 天。两组均接受睡眠卫生指南和每周随访。采用经过验证的问卷来评估干预效果,并使用睡眠日记来评估每天的睡眠开始潜伏期(SOL)、总睡眠时间(TST)和睡眠效率(SE)。基线时抱怨有血管运动症状的参与者则每天记录症状的频率和强度:结果:所有参与者在几乎所有的生活质量领域以及自我评估的 TST 和 SE 方面都获益匪浅。随着时间的推移,芳香组的总体生活质量得分显著提高。在潮热记录和白天嗜睡方面没有观察到差异:结论:芳香疗法干预能有效改善芳香组的整体生活质量。此外,睡眠日记和睡眠卫生指导分别帮助所有参与者自我评估和改善了他们的睡眠模式。
{"title":"Effect of a lavender essential oil and sleep hygiene protocol on insomnia in postmenopausal women: A pilot randomized clinical trial✰✰✰","authors":"Leandro Lucena , Jair Guilherme Santos-Junior , Sergio Tufik , Helena Hachul","doi":"10.1016/j.explore.2023.07.004","DOIUrl":"10.1016/j.explore.2023.07.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Insomnia and vasomotor symptoms are frequently experienced during the menopausal transition and in postmenopause, worsening sleep maintenance and quality of life. Our study evaluated the use of lavender essential oil and sleep hygiene guidance on quality of life, sleep patterns and self-reported hot flashes in postmenopausal women with insomnia diagnosis.</p></div><div><h3>Methods</h3><p>This study is part of a larger experimental, double-blind, randomized controlled trial. We included 35 postmenopausal women with a diagnosis of insomnia who were distributed in two groups: A Placebo group (sunflower oil) and an Aroma group (<em>Lavandula angustifolia</em> essential oil); both inhaled the oils before bedtime for 29 days. The groups received sleep hygiene guidelines and weekly follow-up. Validated questionnaires were used to assess the effect of the intervention, and a sleep diary was used to assess sleep onset latency (SOL), total sleep time (TST), and sleep efficiency (SE) daily. Participants who complained of vasomotor symptoms at baseline kept a daily record of their frequency and intensity.</p></div><div><h3>Results</h3><p>All participants benefited in almost all domains of quality of life and in the self-assessed TST and SE. The Aroma group achieved a significant improvement in their overall quality of life score over time. No differences were observed in respect of the hot flashes record and daytime sleepiness.</p></div><div><h3>Conclusions</h3><p>The aromatherapy intervention was effective in improving the overall quality of life in the Aroma group. Moreover, the sleep diary and sleep hygiene instructions helped all participants to, respectively, self-assess and improve their sleep patterns.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.explore.2023.06.007
Senan Mutlu , Emel Yılmaz , Semra Tutcu Şahin
Context
Pain, abdominal distention, and anxiety are major risk factors encountered after colonoscopy. Complementary and alternative treatments, such as abdominal massage and position change, are used to reduce the associated risk factors.
Objective
To determine the effect of position change and abdominal massage on anxiety, pain, and distension after colonoscopy.
Design
A randomized three-group experimental trial.
Setting and Participants
This study was conducted with 123 patients who underwent colonoscopy at the endoscopy unit of a hospital located in western Turkey.
Methods
Three groups were formed: two interventional (abdominal massage and position change) and one control, each including 41 patients. Data were gathered using a personal information form, pre- and post-colonoscopy measurement form, the Visual Analog Scale (VAS), and the Spielberger State-Trait Anxiety Inventory. Pain and comfort levels, abdominal circumference values, and vital signs of the patients were measured at four evaluation times.
Results
In the abdominal massage group, the VAS pain scores and abdominal circumference measurements decreased the most and the VAS comfort scores increased the most 15 min after the patients were taken to the recovery room (p<0.05). Furthermore, bowel sounds were heard, and bloating was relieved in all patients in both intervention groups 15 min after they were taken to the recovery room.
Conclusions
Abdominal massage and position change can be considered effective interventions for relieving bloating and facilitating flatulence after colonoscopy. Moreover, abdominal massage can be a powerful method for reducing pain and abdominal circumference and increasing patient comfort.
{"title":"The effect of position change and abdominal massage on anxiety, pain and distension after colonoscopy: A randomized clinical trial","authors":"Senan Mutlu , Emel Yılmaz , Semra Tutcu Şahin","doi":"10.1016/j.explore.2023.06.007","DOIUrl":"10.1016/j.explore.2023.06.007","url":null,"abstract":"<div><h3>Context</h3><p>Pain, abdominal distention, and anxiety are major risk factors encountered after colonoscopy. Complementary and alternative treatments, such as abdominal massage and position change, are used to reduce the associated risk factors.</p></div><div><h3>Objective</h3><p>To determine the effect of position change and abdominal massage on anxiety, pain, and distension after colonoscopy.</p></div><div><h3>Design</h3><p>A randomized three-group experimental trial.</p></div><div><h3>Setting and Participants</h3><p>This study was conducted with 123 patients who underwent colonoscopy at the endoscopy unit of a hospital located in western Turkey.</p></div><div><h3>Methods</h3><p>Three groups were formed: two interventional (abdominal massage and position change) and one control, each including 41 patients. Data were gathered using a personal information form, pre- and post-colonoscopy measurement form, the Visual Analog Scale (VAS), and the Spielberger State-Trait Anxiety Inventory. Pain and comfort levels, abdominal circumference values, and vital signs of the patients were measured at four evaluation times.</p></div><div><h3>Results</h3><p>In the abdominal massage group, the VAS pain scores and abdominal circumference measurements decreased the most and the VAS comfort scores increased the most 15 min after the patients were taken to the recovery room (<em>p</em><0.05). Furthermore, bowel sounds were heard, and bloating was relieved in all patients in both intervention groups 15 min after they were taken to the recovery room.</p></div><div><h3>Conclusions</h3><p>Abdominal massage and position change can be considered effective interventions for relieving bloating and facilitating flatulence after colonoscopy. Moreover, abdominal massage can be a powerful method for reducing pain and abdominal circumference and increasing patient comfort.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9718665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.explore.2022.11.004
Tülay KILINÇ , Zeynep KARAMAN ÖZLÜ
Background and objectives
Nausea, vomiting, pain and insomnia in the postoperative period may cause discomfort, and this may adversely affect the patient's compliance with the treatment. This study was conducted to determine the effect of acupressure on nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy.
Methods
This was a randomized controlled experimental study with a placebo group. The sample comprised 188 patients who underwent laparoscopic cholecystectomy (control:64;experimental:64;and placebo:60). Acupressure was performed on the experimental and placebo groups with a wristband for 24 hours. The data were collected at the 0th, 2nd, 6th, 12th, and 24th postoperative hours. Data were collected using the patient introduction form, numeric nausea scale, visual analog scale(VAS), verbal category scale(VCS), and Richards-campbell sleep questionnaire(RCSQ).
Result
The difference between the mean scores of nausea severity and the presence of nausea at the postoperative 0–2, 2–6, and 12–24 hours was statistically significant between the groups and the presence and the severity of nausea was lower in the experimental group (p<0.05). Although not statistically significant, less vomiting was observed in the experimental group patients compared to the control group patients at postoperative 0–2, 2–6, and 12–24 hours. There was no significant difference between the mean VAS and VCS scores of the groups at postoperative 2nd, 6th, and 24th hours (p >0.05). The mean RCSQ total scores of the patients in the experimental group were significantly higher (p<0.001).
Conclusion
Acupressure applied to the PC6 point after laparoscopic cholecystectomy reduced postoperative nausea and vomiting and positively affected sleep quality.
{"title":"Effect of acupressure application on patients’ nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy: A randomized placebo-controlled study","authors":"Tülay KILINÇ , Zeynep KARAMAN ÖZLÜ","doi":"10.1016/j.explore.2022.11.004","DOIUrl":"10.1016/j.explore.2022.11.004","url":null,"abstract":"<div><h3>Background and objectives</h3><p>Nausea, vomiting, pain and insomnia in the postoperative period may cause discomfort, and this may adversely affect the patient's compliance with the treatment. This study was conducted to determine the effect of acupressure on nausea, vomiting, pain, and sleep quality after laparoscopic cholecystectomy.</p></div><div><h3>Methods</h3><p>This was a randomized controlled experimental study with a placebo group. The sample comprised 188 patients who underwent laparoscopic cholecystectomy (control:64;experimental:64;and placebo:60). Acupressure was performed on the experimental and placebo groups with a wristband for 24 hours. The data were collected at the 0th, 2nd, 6th, 12th, and 24th postoperative hours. Data were collected using the patient introduction form, numeric nausea scale, visual analog scale(VAS), verbal category scale(VCS), and Richards-campbell sleep questionnaire(RCSQ).</p></div><div><h3>Result</h3><p>The difference between the mean scores of nausea severity and the presence of nausea at the postoperative 0–2, 2–6, and 12–24 hours was statistically significant between the groups and the presence and the severity of nausea was lower in the experimental group (p<0.05). Although not statistically significant, less vomiting was observed in the experimental group patients compared to the control group patients at postoperative 0–2, 2–6, and 12–24 hours. There was no significant difference between the mean VAS and VCS scores of the groups at postoperative 2<sup>nd</sup>, 6<sup>th</sup>, and 24<sup>th</sup> hours (p >0.05). The mean RCSQ total scores of the patients in the experimental group were significantly higher (p<0.001).</p></div><div><h3>Conclusion</h3><p>Acupressure applied to the PC6 point after laparoscopic cholecystectomy reduced postoperative nausea and vomiting and positively affected sleep quality.</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10350256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.explore.2023.06.002
Tulay Basak, Ayla Demirtas, Senem Duman
Introduction
The study aimed to evaluate the effectiveness of rose oil (Rosa Damascene Mill.) aromatherapy and hand-holding in reducing pain associated with peripheral intravenous catheter insertion.
Methods
A comparative mixed-method design. A total of 126 patients were included in the study. For the study's quantitative data, sociodemographic characteristics of the patients and the Patient Interview Form for the qualitative data of the Numeric Rating Scale were used. In all patients included in the study, PIVC insertion was performed a single time by the same nurse using a standard procedure. Chi-square and Bonferroni tests were used for comparative statistics.
Results
No statistically significant difference between the groups regarding age, gender, marital status, BMI, and education level (p>0.05). Pain scores: it was 2.40±1.78 in the rose oil group, 3.53±1.98 in the hand-holding group, and 4.88±1.56 in the control group. The difference between the groups regarding pain scores is statistically significant (p=0.001).
Conclusions
The study determined that rose oil aromatherapy and hand-holding interventions reduce pain during PIVC. However, rose oil aromatherapy was more effective on pain than the hand-holding intervention.
{"title":"The effect of rose oil aromatherapy and hand-holding on pain due to peripheral intravenous catheter insertion","authors":"Tulay Basak, Ayla Demirtas, Senem Duman","doi":"10.1016/j.explore.2023.06.002","DOIUrl":"10.1016/j.explore.2023.06.002","url":null,"abstract":"<div><h3>Introduction</h3><p>The study aimed to evaluate the effectiveness of rose oil (Rosa Damascene Mill.) aromatherapy and hand-holding in reducing pain associated with peripheral intravenous catheter insertion.</p></div><div><h3>Methods</h3><p>A comparative mixed-method design. A total of 126 patients were included in the study. For the study's quantitative data, sociodemographic characteristics of the patients and the Patient Interview Form for the qualitative data of the Numeric Rating Scale were used. In all patients included in the study, PIVC insertion was performed a single time by the same nurse using a standard procedure. Chi-square and Bonferroni tests were used for comparative statistics.</p></div><div><h3>Results</h3><p>No statistically significant difference between the groups regarding age, gender, marital status, BMI, and education level (p>0.05). Pain scores: it was 2.40±1.78 in the rose oil group, 3.53±1.98 in the hand-holding group, and 4.88±1.56 in the control group. The difference between the groups regarding pain scores is statistically significant (p=0.001).</p></div><div><h3>Conclusions</h3><p>The study determined that rose oil aromatherapy and hand-holding interventions reduce pain during PIVC. However, rose oil aromatherapy was more effective on pain than the hand-holding intervention.</p><p>(Clinical Trial ID: NCT05425849)</p></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9957080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1016/j.explore.2023.12.012
Esra Mustafa
{"title":"Summary of a cochrane review: Dietary interventions for induction and maintenance of remission in inflammatory bowel disease","authors":"Esra Mustafa","doi":"10.1016/j.explore.2023.12.012","DOIUrl":"10.1016/j.explore.2023.12.012","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}