Pub Date : 2007-09-01DOI: 10.1097/01.hjr.0000277985.25720.16
Poncelet Porisms
K CVD is the major cause of premature death in most European populations. It is also a major cause of disability and contributes substantially to the escalating costs of healthcare. K The underlying atherosclerosis develops insidiously over many years and is usually advanced and difficult to reverse by the time that symptoms occur. K Death, myocardial infarction and stroke frequently occur suddenly and before medical help is available. It follows that many therapeutic interventions are either inapplicable (if death occurs suddenly) or palliative. K The mass occurrence of CVD relates strongly to modifiable lifestyle and pathophysiological factors. K CVD is rare in countries where population risk factor levels remain low through adult life. K Risk factor modifications have been unequivocally shown to reduce mortality and morbidity, particularly in high risk patients.
{"title":"Chapter 1: Introduction","authors":"Poncelet Porisms","doi":"10.1097/01.hjr.0000277985.25720.16","DOIUrl":"https://doi.org/10.1097/01.hjr.0000277985.25720.16","url":null,"abstract":"K CVD is the major cause of premature death in most European populations. It is also a major cause of disability and contributes substantially to the escalating costs of healthcare. K The underlying atherosclerosis develops insidiously over many years and is usually advanced and difficult to reverse by the time that symptoms occur. K Death, myocardial infarction and stroke frequently occur suddenly and before medical help is available. It follows that many therapeutic interventions are either inapplicable (if death occurs suddenly) or palliative. K The mass occurrence of CVD relates strongly to modifiable lifestyle and pathophysiological factors. K CVD is rare in countries where population risk factor levels remain low through adult life. K Risk factor modifications have been unequivocally shown to reduce mortality and morbidity, particularly in high risk patients.","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S113 - S2"},"PeriodicalIF":0.0,"publicationDate":"2007-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000277985.25720.16","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61597474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-01DOI: 10.1097/01.hjr.0000244578.40723.de
A. Pelle, S. Pedersen, R. Erdman, Marquita, Spiering, M. Kazemier, J. Denollet, E. Skobel, P. Redanz, S. Schenk, O. Henssen, A. Jendralski, E. Marco, A. Robles, V. Arias, P. Cabero, M. Batlló, F. Escalada, J. Bruguera
Topic category: Rehabilitation European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S78–S104 019 RCT of a cognitive-behavioural programme for people awaiting CABGS G. Furze, K. Irvine, J.C. Dumville, J.N.V. Miles, D.R. Thompson, R.J.P. Lewin University of York, York, United Kingdom Cardiothoracic Centre, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom University of Leicester, Leicester, United Kingdom Objectives The aim of this study was to develop and assess through a randomised controlled trial the ‘‘HeartOp Programme’’, a brief, cognitive-behavioural home-based rehabilitation programme for people waiting for coronary artery bypass graft surgery (CABGS). It was designed to help patients maintain or improve their activity levels and quality of life. Nurse counselling and contact by phone calls during the wait period had already been shown to be effective in improving quality of life so we randomised patients to either the HeartOp Programme or to nurse counselling with written educational materials and regular phone contact. Methods A randomised controlled trial (RCT) of 204 people recruited at entry to the waiting list for first time CABGS. All received a 4560 minute interview with a nurse and phone follow-up at weeks 1, 3 and 6. In addition the 104 control patients received British Heart Foundation booklets about their condition. The 100 intervention patients received the HeartOp Programme. Questionnaire measures (including economic data) were collected prior to randomisation (T1) and after 8 weeks (T2). Primary endpoints were: anxiety (State Trait Anxiety Inventory) and length of hospital stay. Secondary endpoints were: depression (Cardiac Depression Scale), physical functioning (Cardiac Limitations and Symptoms Profile (CLASP) Mobility Scale), misconceptions (Cardiac Beliefs Questionnaire) and cost utility (EQ5D). Data were analysed using intention to treat by analysis of covariance controlling for T1 medical and risk factor variables and the T1 measure of the T2 outcome variable. Results Post-intervention there were no differences between groups in the primary endpoints of anxiety or length of hospital stay. There were significant differences in the secondary endpoints of scores for: depression (difference = 7.79, p = 0.008, 95% CI = 2.04-13.54), physical functioning (difference = 0.82, p = 0.001, 95% CI = 0.34-1.3) and cardiac beliefs (difference = 2.56, p < 0.001, 95% CI = 1.64-3.48) in favour of the HeartOp Programme. The economic analysis suggests that the intervention is likely to be cost effective if implemented. Conclusions The HeartOp home-based cardiac rehabilitation programme appears to add worthwhile and cost effective benefits to a regime of nurse counselling and phone calls. It therefore can be recommended as an additional tool for nurses working with CABG patients in the pre-surgery period. 044 Women participating in phase 3 cardiac cehabilitation: a comparison between mixed and
{"title":"Topic category: Rehabilitation","authors":"A. Pelle, S. Pedersen, R. Erdman, Marquita, Spiering, M. Kazemier, J. Denollet, E. Skobel, P. Redanz, S. Schenk, O. Henssen, A. Jendralski, E. Marco, A. Robles, V. Arias, P. Cabero, M. Batlló, F. Escalada, J. Bruguera","doi":"10.1097/01.hjr.0000244578.40723.de","DOIUrl":"https://doi.org/10.1097/01.hjr.0000244578.40723.de","url":null,"abstract":"Topic category: Rehabilitation European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S78–S104 019 RCT of a cognitive-behavioural programme for people awaiting CABGS G. Furze, K. Irvine, J.C. Dumville, J.N.V. Miles, D.R. Thompson, R.J.P. Lewin University of York, York, United Kingdom Cardiothoracic Centre, Hull and East Yorkshire Hospitals NHS Trust, Hull, United Kingdom University of Leicester, Leicester, United Kingdom Objectives The aim of this study was to develop and assess through a randomised controlled trial the ‘‘HeartOp Programme’’, a brief, cognitive-behavioural home-based rehabilitation programme for people waiting for coronary artery bypass graft surgery (CABGS). It was designed to help patients maintain or improve their activity levels and quality of life. Nurse counselling and contact by phone calls during the wait period had already been shown to be effective in improving quality of life so we randomised patients to either the HeartOp Programme or to nurse counselling with written educational materials and regular phone contact. Methods A randomised controlled trial (RCT) of 204 people recruited at entry to the waiting list for first time CABGS. All received a 4560 minute interview with a nurse and phone follow-up at weeks 1, 3 and 6. In addition the 104 control patients received British Heart Foundation booklets about their condition. The 100 intervention patients received the HeartOp Programme. Questionnaire measures (including economic data) were collected prior to randomisation (T1) and after 8 weeks (T2). Primary endpoints were: anxiety (State Trait Anxiety Inventory) and length of hospital stay. Secondary endpoints were: depression (Cardiac Depression Scale), physical functioning (Cardiac Limitations and Symptoms Profile (CLASP) Mobility Scale), misconceptions (Cardiac Beliefs Questionnaire) and cost utility (EQ5D). Data were analysed using intention to treat by analysis of covariance controlling for T1 medical and risk factor variables and the T1 measure of the T2 outcome variable. Results Post-intervention there were no differences between groups in the primary endpoints of anxiety or length of hospital stay. There were significant differences in the secondary endpoints of scores for: depression (difference = 7.79, p = 0.008, 95% CI = 2.04-13.54), physical functioning (difference = 0.82, p = 0.001, 95% CI = 0.34-1.3) and cardiac beliefs (difference = 2.56, p < 0.001, 95% CI = 1.64-3.48) in favour of the HeartOp Programme. The economic analysis suggests that the intervention is likely to be cost effective if implemented. Conclusions The HeartOp home-based cardiac rehabilitation programme appears to add worthwhile and cost effective benefits to a regime of nurse counselling and phone calls. It therefore can be recommended as an additional tool for nurses working with CABG patients in the pre-surgery period. 044 Women participating in phase 3 cardiac cehabilitation: a comparison between mixed and","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S104 - S78"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000244578.40723.de","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61597331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-01DOI: 10.1097/01.hjr.0000266927.91914.63
D. Sira, G. Zaid, Y. Biniamini, I. Maor, A. Tanchilevitch, M. Sagiv
Topic category: Basic Science European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S1–S12 017 Tissue velocity imaging with dobutamine stress echocardiography– a quantitative technique for identification of coronary artery disease in patients with left bundle branch block H. Badran Background Patients with left bundle branch block exhibit abnormal septal motion which may limit the interpretation of stress echocardiograms and persuade great number of false-positive tests using myocardial scintigraphy. Objectives To analyze whether the use of tissue velocity imaging (TVI) during graded dobutamine infusion is useful to identify and predict coronary artery disease (CAD) in patients with complete left bundlebranch block (LBBB). Methods Sixty-two left bundle branch block patients (mean age 62 years, 34 men) with suspected CAD underwent dobutamine stress – Tissue Doppler echocardiography (DS-TDE) within 6 weeks before coronary arteriography. Dobutamine infusion started at 5 m/k/min and increased up to 40m/k/min with additional atropine during submaximal heart rate responses. Beside wall motion analysis pulsed wave Doppler tissue sampling of mitral annulus at 5 corners were performed at rest in the apical four-chamber plus aorta and two-chamber apical views. The measurements were repeated at low dose (10–15m/k/min), and at peak stress. TDE measurements included peak early systolic (PSV), post systolic shortening (PSS), peak early diastolic (Ve), and peak late diastolic (Va) velocities. The results were compared to 20 healthy subjects as a control. Patients were classified into two groups according to angiographic results, LBBB with CAD (n = 32) and LBBB without CAD (n = 30). Results There was no significant difference between LBBB groups in global WMSI at rest, the D changes in each group was almost similar during peak stress test (P > 0.05). In LBBB with CAD group PSV increased during peak stress to a smaller extent (6.3 ± 1.1 to 7.2 ± 2.0 cm/s, B 24% P < 0.03) than in non CAD group (6.8 ± 1.0 to 9.6 ± 2.7 cm/s, B 46% P < 0.01). Similarly, Ve increased to less extent in CAD group (D Ve 0.2 ± 2.9 versus 2.8 ± 1.7 cm/s, B25% versus 42% P < 0.0001). No significant difference in D Va between LBBB groups and control or between each of them. PSS could be recorded at rest in 24/32 (75%) in CAD and 17/30 (57%) in non CAD group. In LBBB with CAD group PSS was developed and significantly augmented from 4.7 ± 3.1 to 6.3 ± 3.4 cm/s (P < 0.001) during stress. Increment of < 2.5 cm/s in PSV and Ve during peak stress identified CAD with 88% sensitivity and 90% versus 87% specificity, respectively. The cut-off values of PSS velocity > 4 cm/sec at peak stress have strong diagnostic power for prediction of obstructive CAD in LBBB patients (82% accuracy). Conclusion DTE with dobutamine stress allows a diagnostic benefit in the detection of CAD in patients with LBBB. The magnitude of change of peak systolic velocity and early diastolic veloci
主题分类:欧洲心血管疾病预防与康复杂志，2007，多巴酚丁胺应激超声心动图的组织速度成像——一种用于识别左束支阻滞患者冠状动脉疾病的定量技术H. Badran背景左束支阻滞患者表现出异常的间隔运动，这可能会限制应激超声心动图的解释，并导致大量使用心肌显像的假阳性试验。目的分析多巴酚丁胺分级输注时组织速度成像(TVI)对完全左束支传导阻滞(LBBB)患者冠状动脉疾病(CAD)的识别和预测是否有用。方法62例疑似冠心病患者(平均年龄62岁，男性34例)在冠状动脉造影前6周行多巴酚丁胺应激-组织多普勒超声心动图(DS-TDE)检查。多巴酚丁胺输注开始于5 m/k/min，在次最大心率反应期间增加阿托品至40m/k/min。静息时在尖顶四室加主动脉和两室尖顶面对5个角的二尖瓣环进行脉冲波多普勒组织采样。在低剂量(10-15m /k/min)和峰值应力下重复测量。TDE测量包括收缩早期峰值(PSV)、收缩后缩短(PSS)、舒张早期峰值(Ve)和舒张晚期峰值(Va)速度。结果与20名健康受试者作为对照。根据血管造影结果将患者分为合并冠心病的LBBB组(n = 32)和未合并冠心病的LBBB组(n = 30)。结果LBBB组大鼠静息时整体WMSI差异无统计学意义，峰值应激时各组D变化基本相似(P < 0.05)。与非冠心病组(6.8±1.0 ~ 9.6±2.7 cm/s, 46% P < 0.01)相比，冠心病组LBBB在峰值应激时PSV升高幅度(6.3±1.1 ~ 7.2±2.0 cm/s, 24% P < 0.03)较小。同样，CAD组Ve升高幅度较小(D Ve 0.2±2.9 vs 2.8±1.7 cm/s, B25% vs 42% P < 0.0001)。LBBB组与对照组之间或各组之间的dva无显著差异。PSS在CAD组为24/32(75%)，非CAD组为17/30(57%)。LBBB合并CAD组在应激状态下PSS明显增强，从4.7±3.1 cm/s增加到6.3±3.4 cm/s (P < 0.001)。峰值应力时PSV和Ve的增量< 2.5 cm/s，识别CAD的灵敏度分别为88%，特异性分别为90%和87%。峰值应力时PSS速度截断值> ~ 4cm /sec对预测LBBB患者阻塞性CAD具有较强的诊断能力(准确率82%)。结论DTE联合多巴酚丁胺应激对LBBB患者的CAD诊断有一定的价值。在主观壁壁运动分析失败的LBBB患者中，除PSS外，收缩期峰值速度和舒张早期速度的变化幅度是识别CAD的定量参数。
{"title":"Topic category: Basic Science","authors":"D. Sira, G. Zaid, Y. Biniamini, I. Maor, A. Tanchilevitch, M. Sagiv","doi":"10.1097/01.hjr.0000266927.91914.63","DOIUrl":"https://doi.org/10.1097/01.hjr.0000266927.91914.63","url":null,"abstract":"Topic category: Basic Science European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S1–S12 017 Tissue velocity imaging with dobutamine stress echocardiography– a quantitative technique for identification of coronary artery disease in patients with left bundle branch block H. Badran Background Patients with left bundle branch block exhibit abnormal septal motion which may limit the interpretation of stress echocardiograms and persuade great number of false-positive tests using myocardial scintigraphy. Objectives To analyze whether the use of tissue velocity imaging (TVI) during graded dobutamine infusion is useful to identify and predict coronary artery disease (CAD) in patients with complete left bundlebranch block (LBBB). Methods Sixty-two left bundle branch block patients (mean age 62 years, 34 men) with suspected CAD underwent dobutamine stress – Tissue Doppler echocardiography (DS-TDE) within 6 weeks before coronary arteriography. Dobutamine infusion started at 5 m/k/min and increased up to 40m/k/min with additional atropine during submaximal heart rate responses. Beside wall motion analysis pulsed wave Doppler tissue sampling of mitral annulus at 5 corners were performed at rest in the apical four-chamber plus aorta and two-chamber apical views. The measurements were repeated at low dose (10–15m/k/min), and at peak stress. TDE measurements included peak early systolic (PSV), post systolic shortening (PSS), peak early diastolic (Ve), and peak late diastolic (Va) velocities. The results were compared to 20 healthy subjects as a control. Patients were classified into two groups according to angiographic results, LBBB with CAD (n = 32) and LBBB without CAD (n = 30). Results There was no significant difference between LBBB groups in global WMSI at rest, the D changes in each group was almost similar during peak stress test (P > 0.05). In LBBB with CAD group PSV increased during peak stress to a smaller extent (6.3 ± 1.1 to 7.2 ± 2.0 cm/s, B 24% P < 0.03) than in non CAD group (6.8 ± 1.0 to 9.6 ± 2.7 cm/s, B 46% P < 0.01). Similarly, Ve increased to less extent in CAD group (D Ve 0.2 ± 2.9 versus 2.8 ± 1.7 cm/s, B25% versus 42% P < 0.0001). No significant difference in D Va between LBBB groups and control or between each of them. PSS could be recorded at rest in 24/32 (75%) in CAD and 17/30 (57%) in non CAD group. In LBBB with CAD group PSS was developed and significantly augmented from 4.7 ± 3.1 to 6.3 ± 3.4 cm/s (P < 0.001) during stress. Increment of < 2.5 cm/s in PSV and Ve during peak stress identified CAD with 88% sensitivity and 90% versus 87% specificity, respectively. The cut-off values of PSS velocity > 4 cm/sec at peak stress have strong diagnostic power for prediction of obstructive CAD in LBBB patients (82% accuracy). Conclusion DTE with dobutamine stress allows a diagnostic benefit in the detection of CAD in patients with LBBB. The magnitude of change of peak systolic velocity and early diastolic veloci","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S1 - S12"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000266927.91914.63","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61597395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-01DOI: 10.1097/01.hjr.0000244577.63594.e1
D. Georgescu, M. Costa, A. Antunes, A. Coelho, P. Mota, -. A.Leitão, Marques, M. Sandrock, K. Winkler, L. Klatt, E. Bitzer, K. Böttcher
Topic category: Prevention European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S47–S77 011 Type-D personality but not ICD indication is associated with impaired health-related quality of life 3 months post implantation S.S. Pedersen, D.A.M.J. Theuns, A. Muskens-Heemskerk, R.A.M. Erdman, L. Jordaens CoRPS-Department of Medical Psychology, Tilburg University, Tilburg, The Netherlands Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands Department of Medical Psychology and Psychotherapy, Erasmus Medical Centre, Rotterdam, The Netherlands Objectives Indications for the implantation of an implantable cardioverter defibrillator (ICD) have expanded since the device was first introduced, with current guidelines recommending its use in both primary and secondary prevention. Although the superiority of device therapy compared to anti-arrhythmic drugs for the primary prevention of sudden cardiac death in high-risk patients is well established, little is known about the impact of ICD indication on health-related quality of life (HRQL). Indication may also interact with psychological factors, such as personality. Using a prospective design, we examined whether ICD indication and type-D personality (i.e. experiencing increased negative emotions paired with emotional non-expression) serve as modulators of HRQL at baseline and 3 months post-implantation. Methods Consecutively implanted ICD patients (n = 154) completed the Type-D Scale (DS14) at baseline and the Short-Form Health Survey 36 (SF-36) at baseline and 3 months. Results Of all patients, 82 (53%) received an ICD due to prophylactic reasons; the prevalence of type-D was 23%. ANOVA for repeated measures showed that indication had no influence on HRQL (p = 0.75). Further stratification by personality showed a main effect for type-D personality (p < 0.001), with type-D patients generally experiencing poorer HRQL; there was no main effect for indication (p = 0.45) nor was the interaction effect indication by type-D significant (p = 0.22). However, there was a significant improvement in HRQL over time (p = 0.001). Adjusting for clinical factors and shocks during follow-up, Type-D remained an independent predictor of impaired HRQL (p < 0.001), although there was no longer a significant change in HRQL over time (p = 0.099). Conclusions Type-D personality but not ICD indication was associated with impaired HRQL at the time of implantation and at 3 months, with type-D exerting an effect on HRQL independent of shocks and other risk factors. In the quest for enhancing risk stratification in clinical practice, personality factors, such as type-D, should not be ignored, as both type-D and poor HRQL have been associated with increased risk of mortality in cardiac patients. 014 Low density lipoprotein subclass distribution in children with renal diseases S. Alabakovska, D. Labudovic, K. Tosheska, M. Alabakovski, B. Todorova Medical Faculty, Departme
{"title":"Topic category: Prevention","authors":"D. Georgescu, M. Costa, A. Antunes, A. Coelho, P. Mota, -. A.Leitão, Marques, M. Sandrock, K. Winkler, L. Klatt, E. Bitzer, K. Böttcher","doi":"10.1097/01.hjr.0000244577.63594.e1","DOIUrl":"https://doi.org/10.1097/01.hjr.0000244577.63594.e1","url":null,"abstract":"Topic category: Prevention European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S47–S77 011 Type-D personality but not ICD indication is associated with impaired health-related quality of life 3 months post implantation S.S. Pedersen, D.A.M.J. Theuns, A. Muskens-Heemskerk, R.A.M. Erdman, L. Jordaens CoRPS-Department of Medical Psychology, Tilburg University, Tilburg, The Netherlands Department of Cardiology, Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands Department of Medical Psychology and Psychotherapy, Erasmus Medical Centre, Rotterdam, The Netherlands Objectives Indications for the implantation of an implantable cardioverter defibrillator (ICD) have expanded since the device was first introduced, with current guidelines recommending its use in both primary and secondary prevention. Although the superiority of device therapy compared to anti-arrhythmic drugs for the primary prevention of sudden cardiac death in high-risk patients is well established, little is known about the impact of ICD indication on health-related quality of life (HRQL). Indication may also interact with psychological factors, such as personality. Using a prospective design, we examined whether ICD indication and type-D personality (i.e. experiencing increased negative emotions paired with emotional non-expression) serve as modulators of HRQL at baseline and 3 months post-implantation. Methods Consecutively implanted ICD patients (n = 154) completed the Type-D Scale (DS14) at baseline and the Short-Form Health Survey 36 (SF-36) at baseline and 3 months. Results Of all patients, 82 (53%) received an ICD due to prophylactic reasons; the prevalence of type-D was 23%. ANOVA for repeated measures showed that indication had no influence on HRQL (p = 0.75). Further stratification by personality showed a main effect for type-D personality (p < 0.001), with type-D patients generally experiencing poorer HRQL; there was no main effect for indication (p = 0.45) nor was the interaction effect indication by type-D significant (p = 0.22). However, there was a significant improvement in HRQL over time (p = 0.001). Adjusting for clinical factors and shocks during follow-up, Type-D remained an independent predictor of impaired HRQL (p < 0.001), although there was no longer a significant change in HRQL over time (p = 0.099). Conclusions Type-D personality but not ICD indication was associated with impaired HRQL at the time of implantation and at 3 months, with type-D exerting an effect on HRQL independent of shocks and other risk factors. In the quest for enhancing risk stratification in clinical practice, personality factors, such as type-D, should not be ignored, as both type-D and poor HRQL have been associated with increased risk of mortality in cardiac patients. 014 Low density lipoprotein subclass distribution in children with renal diseases S. Alabakovska, D. Labudovic, K. Tosheska, M. Alabakovski, B. Todorova Medical Faculty, Departme","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S47 - S77"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000244577.63594.e1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61597325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-04-01DOI: 10.1097/01.hjr.0000266929.37656.4c
T. Hara, H. Ishii, Y. Shiotani, T. Kawashima, S. Asakura, K. Nakao, Y. Fujioka, A. Fukuda, Y. Kimura, M. Yokoyama, K. Ishii, L. Naylor, C. Weisbrod, G. O'driscoll, K. Reiss, D. Warburton, N. Jendzjowsky, Y. Liang, B. Esch, R. Haennel, Y. Bhambhani, M. Haykowsky
Topic category: Exercise Physiology European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S36–S46 007 Statins in intermittent claudication: a meta-analysis A.S. De Guzman, M.P. Luque St Luke’s Medical Center, Heart Institute Quezon City, Philippines Background Intermittent claudication is always been bothersome to patients with peripheral arterial disease. These patients suffer lower limb pain limiting their activity and independence. The benefit of statins among claudicants still remains unclear. The objective of this meta-analysis is to determine the efficacy of statin treatment among patients with intermittent claudication. Methods Clinical trials were identified from Medline search, PUBMED, and Cochrane collaboration databases 1999 to 2006. A total of 12 articles were queried, 8 of which are RCTs and were subjected to data extraction and quality scale. Independent quality assessment scale and the inclusion criteria were strictly applied. A total of 3 trials were included in the study. All included studies were randomized controlled trials involving a total of 380 PAD patients with intermittent claudication (Fontaine class II) and an Ankle-Brachial index of less than 0.90. Patients with previous surgery/angioplasty for PAOD, any condition that limits their ability to perform exercise test like previous MI patients/CABG within 6 months, unstable angina, neurologic disease, arthritis, uncontrolled hypertension, DVT before 3 months of randomization. Patients who had previously been treated with statins or other cholesterol lowering drugs were also excluded. Main Results The analysis of the mean walking distance showed a significant improvement from baseline as compared with the placebo at 95% CI (2.31, df – 1) P: < 0.00001. The analysis in terms of pain-free walking distance also showed a significant improvement in the pain-free walking distance from baseline as compared with the placebo at 95% CI (0.04, df – 2) P: < 0.00001. Conclusion Statins are beneficial among claudicant patients with significant improvement of mean walking distance and increase in pain-free walking distance with treatment duration of 6 to 12 months. 010 Attitude towards physical activity and body mass index in fourth class Dublin schoolchildren M. Guidon, F. Crehan, C. Crowley School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland Objectives The objective was to assess the attitudes of fourth-class schoolchildren (9-11 years) to physical activity and to determine the relationship, if any, between attitudes and body mass index (BMI). An additional objective was to compare attitudes towards physical activity between boys and girls and between children in mixed and single sex schools. Methods Following ethical approval, the Grade 3 Children’s Attitude Toward Physical Activity Inventory (CAPTA) was administered to 124 schoolchildren in one single-sex boy’s school, one single–sex girl’s school and one mixed school. A survey
{"title":"Topic category: Exercise Physiology","authors":"T. Hara, H. Ishii, Y. Shiotani, T. Kawashima, S. Asakura, K. Nakao, Y. Fujioka, A. Fukuda, Y. Kimura, M. Yokoyama, K. Ishii, L. Naylor, C. Weisbrod, G. O'driscoll, K. Reiss, D. Warburton, N. Jendzjowsky, Y. Liang, B. Esch, R. Haennel, Y. Bhambhani, M. Haykowsky","doi":"10.1097/01.hjr.0000266929.37656.4c","DOIUrl":"https://doi.org/10.1097/01.hjr.0000266929.37656.4c","url":null,"abstract":"Topic category: Exercise Physiology European Journal of Cardiovascular Prevention and Rehabilitation, 2007, 14 (suppl 1):S36–S46 007 Statins in intermittent claudication: a meta-analysis A.S. De Guzman, M.P. Luque St Luke’s Medical Center, Heart Institute Quezon City, Philippines Background Intermittent claudication is always been bothersome to patients with peripheral arterial disease. These patients suffer lower limb pain limiting their activity and independence. The benefit of statins among claudicants still remains unclear. The objective of this meta-analysis is to determine the efficacy of statin treatment among patients with intermittent claudication. Methods Clinical trials were identified from Medline search, PUBMED, and Cochrane collaboration databases 1999 to 2006. A total of 12 articles were queried, 8 of which are RCTs and were subjected to data extraction and quality scale. Independent quality assessment scale and the inclusion criteria were strictly applied. A total of 3 trials were included in the study. All included studies were randomized controlled trials involving a total of 380 PAD patients with intermittent claudication (Fontaine class II) and an Ankle-Brachial index of less than 0.90. Patients with previous surgery/angioplasty for PAOD, any condition that limits their ability to perform exercise test like previous MI patients/CABG within 6 months, unstable angina, neurologic disease, arthritis, uncontrolled hypertension, DVT before 3 months of randomization. Patients who had previously been treated with statins or other cholesterol lowering drugs were also excluded. Main Results The analysis of the mean walking distance showed a significant improvement from baseline as compared with the placebo at 95% CI (2.31, df – 1) P: < 0.00001. The analysis in terms of pain-free walking distance also showed a significant improvement in the pain-free walking distance from baseline as compared with the placebo at 95% CI (0.04, df – 2) P: < 0.00001. Conclusion Statins are beneficial among claudicant patients with significant improvement of mean walking distance and increase in pain-free walking distance with treatment duration of 6 to 12 months. 010 Attitude towards physical activity and body mass index in fourth class Dublin schoolchildren M. Guidon, F. Crehan, C. Crowley School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland Objectives The objective was to assess the attitudes of fourth-class schoolchildren (9-11 years) to physical activity and to determine the relationship, if any, between attitudes and body mass index (BMI). An additional objective was to compare attitudes towards physical activity between boys and girls and between children in mixed and single sex schools. Methods Following ethical approval, the Grade 3 Children’s Attitude Toward Physical Activity Inventory (CAPTA) was administered to 124 schoolchildren in one single-sex boy’s school, one single–sex girl’s school and one mixed school. A survey ","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"S36 - S46"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000266929.37656.4c","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61597907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2007-02-01DOI: 10.1097/S1741-8267(07)14125-6
A. Rosengren, S. Maugeri
Professor Pantaleo Giannuzzi Professor Annika Rosengren Salvatore Maugeri Foundation The Cardiovascular Institute IRCCS, Cardiology Department Gr för kardiovascular forskn Medical Centre of Veruno Medicin, plan 2 CK Via Revislate 13 SU/Östra I-28010 Veruno, Italy 416 85 Göteborg, Austria Tel: + 39 0322 884711 Tel: + 46 31 343 4086 Fax: 32 0322 884816 Fax: + 46 31 259 254 E-mail: pgiannuzzi@fsm.it E-mail: annika.rosengren@hjl.gu.se
{"title":"News and Notices","authors":"A. Rosengren, S. Maugeri","doi":"10.1097/S1741-8267(07)14125-6","DOIUrl":"https://doi.org/10.1097/S1741-8267(07)14125-6","url":null,"abstract":"Professor Pantaleo Giannuzzi Professor Annika Rosengren Salvatore Maugeri Foundation The Cardiovascular Institute IRCCS, Cardiology Department Gr för kardiovascular forskn Medical Centre of Veruno Medicin, plan 2 CK Via Revislate 13 SU/Östra I-28010 Veruno, Italy 416 85 Göteborg, Austria Tel: + 39 0322 884711 Tel: + 46 31 343 4086 Fax: 32 0322 884816 Fax: + 46 31 259 254 E-mail: pgiannuzzi@fsm.it E-mail: annika.rosengren@hjl.gu.se","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":"14 1","pages":"155 - 158"},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61794711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2006-08-01DOI: 10.1097/01.hjr.0000219111.02544.ff
Apostolos I Karavidas, Kostadinos G Raisakis, John T Parissis, Dorothea K Tsekoura, Stamatis Adamopoulos, Dimitrios A Korres, Dimitrios Farmakis, Achilleas Zacharoulis, Ioannis Fotiadis, Evaggelos Matsakas, Apostolos Zacharoulis
Background: Previous studies have shown beneficial effects of functional electrical stimulation (FES) on muscle performance and exercise capacity of patients with chronic heart failure. This study evaluates the impact of FES on endothelial function and peripheral markers of immune activation in patients with moderate to severe heart failure.
Methods: Twenty-four patients with a left ventricular ejection fraction of less than 40% and New York Heart Association class II-III symptoms, undergoing optimized drug therapy, were randomly assigned (2 : 1) to a 6-week training programme of FES (n=16) or served as controls (n=8). Endothelial function was assessed by Doppler flow-mediated dilatation (FMD) of the brachial artery before and after the training programme. Peripheral pro-inflammatory/anti-inflammatory markers such as tumour necrosis factor (TNF)-alpha, interleukin (IL)-6, soluble intercellular adhesion molecule (sICAM)-1, soluble vascular cell adhesion molecule (sVCAM)-1 and IL-10 were also measured before and after training.
Results: A significant improvement on the 6-min walk test (7.5+/-3.3%), Minnesota Living Score (18.2+/-8.6%) and FMD (38.5+/-15.1%) was observed only in the FES-treated group. FES also causes a significant reduction of TNF-alpha (-11.5+/-8.9%), sICAM-1 (-13.1+/-9.8%), and sVCAM-1 (-10.6+/-6.6%), as well as a respective increase in the ratio IL-10/TNF-alpha (37.1+/-29.4%). In the FES group, the percentage improvement in the Minnesota Living Score was significantly correlated with respective changes in circulating TNF-alpha (r=0.624, P<0.01), sVCAM-1 (r=0.665, P<0.001) and the ratio IL-10/TNF-alpha (r=-0.641, P<0.01).
Conclusion: FES is an exercise training programme that improves endothelial function in patients with chronic heart failure, and also has anti-inflammatory effects.
{"title":"Functional electrical stimulation improves endothelial function and reduces peripheral immune responses in patients with chronic heart failure.","authors":"Apostolos I Karavidas, Kostadinos G Raisakis, John T Parissis, Dorothea K Tsekoura, Stamatis Adamopoulos, Dimitrios A Korres, Dimitrios Farmakis, Achilleas Zacharoulis, Ioannis Fotiadis, Evaggelos Matsakas, Apostolos Zacharoulis","doi":"10.1097/01.hjr.0000219111.02544.ff","DOIUrl":"https://doi.org/10.1097/01.hjr.0000219111.02544.ff","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have shown beneficial effects of functional electrical stimulation (FES) on muscle performance and exercise capacity of patients with chronic heart failure. This study evaluates the impact of FES on endothelial function and peripheral markers of immune activation in patients with moderate to severe heart failure.</p><p><strong>Methods: </strong>Twenty-four patients with a left ventricular ejection fraction of less than 40% and New York Heart Association class II-III symptoms, undergoing optimized drug therapy, were randomly assigned (2 : 1) to a 6-week training programme of FES (n=16) or served as controls (n=8). Endothelial function was assessed by Doppler flow-mediated dilatation (FMD) of the brachial artery before and after the training programme. Peripheral pro-inflammatory/anti-inflammatory markers such as tumour necrosis factor (TNF)-alpha, interleukin (IL)-6, soluble intercellular adhesion molecule (sICAM)-1, soluble vascular cell adhesion molecule (sVCAM)-1 and IL-10 were also measured before and after training.</p><p><strong>Results: </strong>A significant improvement on the 6-min walk test (7.5+/-3.3%), Minnesota Living Score (18.2+/-8.6%) and FMD (38.5+/-15.1%) was observed only in the FES-treated group. FES also causes a significant reduction of TNF-alpha (-11.5+/-8.9%), sICAM-1 (-13.1+/-9.8%), and sVCAM-1 (-10.6+/-6.6%), as well as a respective increase in the ratio IL-10/TNF-alpha (37.1+/-29.4%). In the FES group, the percentage improvement in the Minnesota Living Score was significantly correlated with respective changes in circulating TNF-alpha (r=0.624, P<0.01), sVCAM-1 (r=0.665, P<0.001) and the ratio IL-10/TNF-alpha (r=-0.641, P<0.01).</p><p><strong>Conclusion: </strong>FES is an exercise training programme that improves endothelial function in patients with chronic heart failure, and also has anti-inflammatory effects.</p>","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":" ","pages":"592-7"},"PeriodicalIF":0.0,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000219111.02544.ff","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26168066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The objective of this study was to perform a population-based screening programme to determine the prevalence of the metabolic syndrome (MetS) and the relationship between metabolic risk factors and prevalent cardiovascular complications in Taiwan.
Design: A screening programme recruited residents aged 40 years and older in Sanchih, Taipei County, Taiwan, and collected demographic data, blood and urine samples. Fasting plasma glucose level, serum total cholesterol, high-density lipoprotein cholesterol, and triglyceride were measured. Atherosclerotic complications, including myocardial infarction, stress-positive angina, ischaemic stroke, and proteinuria were confirmed.
Methods: A structural equation model (SEM) was constructed to identify the association between metabolic abnormality and atherosclerosis.
Results: A total of 1494 subjects, 776 male and 718 female, were recruited in this study. The crude prevalence of the MetS was 19.3% for men [95% confidence interval (CI) 16.3-22.2%] and 18.7% for women (95% CI 15.6-22.0%). The presence of the MetS posed a substantial risk to microvascular complications in both sexes [odds ratio (OR) 3.29, P<0.001] and to macrovascular complications in men (OR 1.95, P=0.04) and also a trend in women (OR 2.24, P=0.089). There was a positive association between metabolic abnormality and atherosclerosis (B=0.55, P<0.001).
Conclusions: This study has found the prevalence of the MetS and the association with atherosclerotic complications in Taiwan. The SEM approach has demonstrated a positive correlation between metabolic abnormality and atherosclerosis and can be used to explore new risk factors for cardiovascular diseases.
背景:本研究的目的是进行一项以人群为基础的筛查计划，以确定台湾代谢综合征(MetS)的患病率，以及代谢危险因素与心血管并发症患病率之间的关系。设计:筛选台湾台北县三池市40岁及以上的居民，收集人口统计资料、血液和尿液样本。测定空腹血糖水平、血清总胆固醇、高密度脂蛋白胆固醇和甘油三酯。动脉粥样硬化并发症，包括心肌梗死，应激性心绞痛，缺血性脑卒中和蛋白尿被证实。方法:建立结构方程模型，探讨代谢异常与动脉粥样硬化的关系。结果:共纳入受试者1494人，其中男性776人，女性718人。met的粗患病率男性为19.3%[95%可信区间(CI) 16.3-22.2%]，女性为18.7% (95% CI 15.6-22.0%)。MetS的存在对两性微血管并发症都有很大的风险[优势比(OR) 3.29, p]。结论:本研究发现台湾地区MetS的患病率及其与动脉粥样硬化并发症的关系。扫描电镜方法已证明代谢异常与动脉粥样硬化之间存在正相关，可用于探索心血管疾病的新危险因素。
{"title":"Using structural equation model to illustrate the relationship between metabolic risk factors and cardiovascular complications in Taiwan.","authors":"Jou-Wei Lin, Juey-Jen Hwang, Dao-Fu Dai, Yung-Zu Tseng","doi":"10.1097/01.hjr.0000230095.65062.a9","DOIUrl":"https://doi.org/10.1097/01.hjr.0000230095.65062.a9","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to perform a population-based screening programme to determine the prevalence of the metabolic syndrome (MetS) and the relationship between metabolic risk factors and prevalent cardiovascular complications in Taiwan.</p><p><strong>Design: </strong>A screening programme recruited residents aged 40 years and older in Sanchih, Taipei County, Taiwan, and collected demographic data, blood and urine samples. Fasting plasma glucose level, serum total cholesterol, high-density lipoprotein cholesterol, and triglyceride were measured. Atherosclerotic complications, including myocardial infarction, stress-positive angina, ischaemic stroke, and proteinuria were confirmed.</p><p><strong>Methods: </strong>A structural equation model (SEM) was constructed to identify the association between metabolic abnormality and atherosclerosis.</p><p><strong>Results: </strong>A total of 1494 subjects, 776 male and 718 female, were recruited in this study. The crude prevalence of the MetS was 19.3% for men [95% confidence interval (CI) 16.3-22.2%] and 18.7% for women (95% CI 15.6-22.0%). The presence of the MetS posed a substantial risk to microvascular complications in both sexes [odds ratio (OR) 3.29, P<0.001] and to macrovascular complications in men (OR 1.95, P=0.04) and also a trend in women (OR 2.24, P=0.089). There was a positive association between metabolic abnormality and atherosclerosis (B=0.55, P<0.001).</p><p><strong>Conclusions: </strong>This study has found the prevalence of the MetS and the association with atherosclerotic complications in Taiwan. The SEM approach has demonstrated a positive correlation between metabolic abnormality and atherosclerosis and can be used to explore new risk factors for cardiovascular diseases.</p>","PeriodicalId":50492,"journal":{"name":"European Journal of Cardiovascular Prevention & Rehabilitation","volume":" ","pages":"633-9"},"PeriodicalIF":0.0,"publicationDate":"2006-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/01.hjr.0000230095.65062.a9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26168072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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