Pub Date : 2024-01-15DOI: 10.22270/jddt.v14i1.6374
Hermien Nugraheni, Lanny Sunarjo, S. Sukini, A. N. Prayoga
Aim: To analyze the relationship between maternal characteristics and actions to maintain children's oral health with oral hygiene in primary school-aged children Method: This type of research is quantitative analytical with a cross-sectional approach. The population is students from SD Negeri Seberang Mesjid 1 Banjarmasin. The sample was taken using a purposive sampling technique of 5th-grade students and their mothers. Data collection on characteristics and perspectives of maternal actions used a questionnaire instrument. Meanwhile, data on oral hygiene uses the Oral Hygiene Index Simplified (OHI-S) examination sheet. Data analysis used an alternative relationship test, namely Fisher's Exact Test. Results: Most mothers (47.1%) had actions to maintain their children's oral health in the good category. Meanwhile, most children's oral hygiene (49.4%) was in the poor category. The results of the correlation test showed (p-value) that the child's oral hygiene with the mother’s education = 0.000, the mother’s occupation = 0.001, the mother’s exposure to information = 0.000, the family’s income = 0.014, and the mother's age = 0.596. In the correlation test between the mother's actions in maintaining her child's oral health and the children's oral hygiene, it was found that p-value = 0.000. Conclusion: There is a significant relationship between maternal characteristics which include: education, occupation, family income, and the mother's actions. Meanwhile, the mother's age is not significantly related to the mother's actions. There is a significant relationship between the mother's actions in maintaining her child's oral health and the oral hygiene of primary school-aged children. Keywords: characteristic, perspective actions, oral hygiene
目的：分析小学学龄儿童的母亲特征与维护儿童口腔健康的行动与口腔卫生之间的关系：本研究为横断面定量分析。研究对象是来自 Banjarmasin Negeri Seberang Mesjid 1 区的学生。样本采用目的性抽样技术，从五年级学生及其母亲中抽取。关于母亲行为的特点和观点的数据收集采用了问卷调查的方式。同时，口腔卫生数据采用口腔卫生指数简化（OHI-S）检查表。数据分析采用替代关系检验，即费雪精确检验。结果大多数母亲（47.1%）在保持孩子口腔健康方面采取了良好的行动。与此同时，大多数儿童（49.4%）的口腔卫生状况属于较差类别。相关性检验结果显示（P 值），儿童的口腔卫生与母亲的教育程度=0.000，母亲的职业=0.001，母亲的信息接触=0.000，家庭收入=0.014，母亲的年龄=0.596。在母亲维护儿童口腔健康的行为与儿童口腔卫生之间的相关性检验中，发现 p 值 = 0.000。结论母亲的特征（包括教育程度、职业、家庭收入）与母亲的行为之间存在明显的关系。同时，母亲的年龄与母亲的行为没有明显关系。母亲维护孩子口腔健康的行动与小学学龄儿童的口腔卫生之间存在明显的关系。关键词：特征；视角行动；口腔卫生
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Sodium alginate and poloxamer 407 were both studied in order to design a hydrogel-based delivery system as a platform for the formulation of vaginal medecines. Sodium alginate is a natural anionic mucoadhesive polymer while poloxamer 407 is a temperature-sensitive polymer. A commercial alginate was characterized. Then, its solutions (0.5-2 % w/w), poloxamer 407 solutions (16-21.5 % w/w) and their mixtures were prepared. Their rheological properties and the influence of vaginal simulated fluid were assessed. This commercial alginate had a mannuronate-to-guluronate ratio of 1.24, a weight-average molecular weight of 300 000 ± 2% g.mol-1, a polydispersity index of 1.8 ± 3%. Alginate solutions displayed a viscous behavior not suitable for a vaginal administration. Poloxamer solutions and their mixtures with alginate were temperature-sensitive, shear-thinning, non-thixotropic and had an elastic behavior suitable for a vaginal administration. Their resistance to dilution with vaginal fluid could prolonge vaginal residence. Keywords: Formulation, poloxamer 407, rheology, sodium alginate, temperature–sensitive, vaginal fluid, viscoelastic properties.
{"title":"Gels Containing Poloxamer 407 and Sodium Alginate as Vehicles for Vaginal Administration","authors":"Kakwokpo Clémence N’GUESSAN-GNAMAN, Awa Nakognon TUO-KOUASSI, Sandrine AKA-ANY-GRAH, Rosine Désirée CHOUGOUO KENGNE-NKUITCHOU, Apo Laurette Anin, A. Lia, Alain N’GUESSAN, Ismael Dally","doi":"10.22270/jddt.v14i1.6348","DOIUrl":"https://doi.org/10.22270/jddt.v14i1.6348","url":null,"abstract":"Sodium alginate and poloxamer 407 were both studied in order to design a hydrogel-based delivery system as a platform for the formulation of vaginal medecines. Sodium alginate is a natural anionic mucoadhesive polymer while poloxamer 407 is a temperature-sensitive polymer. A commercial alginate was characterized. Then, its solutions (0.5-2 % w/w), poloxamer 407 solutions (16-21.5 % w/w) and their mixtures were prepared. Their rheological properties and the influence of vaginal simulated fluid were assessed. This commercial alginate had a mannuronate-to-guluronate ratio of 1.24, a weight-average molecular weight of 300 000 ± 2% g.mol-1, a polydispersity index of 1.8 ± 3%. Alginate solutions displayed a viscous behavior not suitable for a vaginal administration. Poloxamer solutions and their mixtures with alginate were temperature-sensitive, shear-thinning, non-thixotropic and had an elastic behavior suitable for a vaginal administration. Their resistance to dilution with vaginal fluid could prolonge vaginal residence. \u0000Keywords: Formulation, poloxamer 407, rheology, sodium alginate, temperature–sensitive, vaginal fluid, viscoelastic properties.","PeriodicalId":506928,"journal":{"name":"Journal of Drug Delivery and Therapeutics","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139622252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-15DOI: 10.22270/jddt.v14i1.6250
Cicilien Quentin Nongni Piebeng, Bruno Dupon Ambamba Akamba, Fils Armand Ella, Agwe Nicoline Injoh, D. Ngoumen, D. Mandob, J. Ngondi
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{"title":"In silico anti-Alzheimer potential of bioactive compounds in fungi from the African Natural Products Database","authors":"Cicilien Quentin Nongni Piebeng, Bruno Dupon Ambamba Akamba, Fils Armand Ella, Agwe Nicoline Injoh, D. Ngoumen, D. Mandob, J. Ngondi","doi":"10.22270/jddt.v14i1.6250","DOIUrl":"https://doi.org/10.22270/jddt.v14i1.6250","url":null,"abstract":"Download and view PDF for abstract","PeriodicalId":506928,"journal":{"name":"Journal of Drug Delivery and Therapeutics","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139622352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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