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The Economical and Geographical Importance of Lapis Route 青金石之路的经济和地理重要性
Pub Date : 2024-05-08 DOI: 10.55544/jrasb.3.2.28
Mohammad Zaman Samoon, Noor Ahmad Ahmadi
This research explores the intricate web of the Lapis Route, an ancient trade route that formerly linked Afghanistan with the Mediterranean Sea. This study examines the geographical and historical relevance of this ancient road using a qualitative research approach, building on insights from numerous books, journals, and other sources. It focuses on the valuable lapis lazuli gemstone that contributed to the route's notoriety.  The research delves into the various segments of the Lapis Route and its convergence with the Silk Road, unveiling the complex web of commerce that thrived amongst various societies. It reveals the significance of the Silk Road historically and emphasizes how it shaped both economic development and cross-cultural exchange.  In addition, the study looks into the economic importance of silk, a highly prized item that traveled the Silk Road and supported the region's economy. The study concludes by examining the historical, cultural, and economic significance of the Silk Road and the Lapis Route in Afghanistan. The report addresses the opportunities and problems related to transit and commercial development, emphasizing the possible advantages of reviving the Silk Road. It highlights the possibilities that the revival of this historic trade route holds for fostering regional collaboration and economic progress.  This study provides important insights into the historical, geographical, and economic relevance of the Silk Road and the Lapis Route by analyzing them. It draws attention to the routes' lasting impact and their potential to support Afghanistan's and the region's future economic growth.
这项研究探索了拉普斯之路错综复杂的网络,这条古商路曾连接阿富汗和地中海。本研究采用定性研究方法,从大量书籍、期刊和其他资料中汲取灵感,探讨了这条古道的地理和历史意义。研究的重点是促成这条古道声名远播的珍贵青金石宝石。 研究深入青金石之路的各个环节及其与丝绸之路的交汇点,揭示了不同社会之间繁荣发展的复杂商业网络。研究揭示了丝绸之路的历史意义,强调了丝绸之路是如何影响经济发展和跨文化交流的。 此外,研究还探讨了丝绸在经济上的重要性,丝绸是丝绸之路上的珍贵物品,支撑着该地区的经济。研究报告最后探讨了丝绸之路和阿富汗青金石之路的历史、文化和经济意义。报告探讨了与过境和商业发展相关的机遇和问题,强调了复兴丝绸之路的可能优势。报告强调了复兴这条历史悠久的贸易路线对于促进地区合作和经济进步的可能性。 本研究通过分析丝绸之路和拉普斯之路,对其历史、地理和经济意义提供了重要见解。它提请人们注意这两条路线的持久影响及其支持阿富汗和该地区未来经济增长的潜力。
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引用次数: 0
Effect of Different Levels of Nitrogen on Growth, Yield and Productivity of Wheat (Triticum estivum L.) Cv. Koshan-02 不同氮素水平对小麦(Triticum estivum L.)Cv. 生长、产量和生产力的影响Koshan-02
Pub Date : 2024-05-06 DOI: 10.55544/jrasb.3.2.26
Mohammad Hasham Popal, Mohammad Yar Malakzai, Soorgul Sandakhil
The field experiment was conducted to study the effect of different levels (0, 50, 70, 90 & 110 kg N ha-1) of Nitrogen (N) on growth, yield and yield related parameters of wheat (cv. Koshan-02) in Kabul agro-climate condition at the Agricultural Research Farm of Kabul University, during spring 2020-21. The experiment was laid out in Randomized Complete Block Design (RCBD) with three replications, each replication consisted of five treatments. Total treatments were (15). The size of each plot was (2mx3m=6m2). The result of our study revealed that the plots treated with highest level (110 kg N ha-1) of N fertilizers produced the highest plant height (85.97cm). maximum number of grains spike-1 (35.74), the highest dry matter (3.937t ha-1), The highest number of tillers m-2 (152.76 m-2), 1000-grain weight (48.94g), grain yield (2891.1kg/ha) large spike length (10.52), number of grains spikelet-1 (2.98), Spikelet number spike-1 (11.54), followed by T4, T3 and T2. It was concluded that all treatments have ranked regarding their efficient effects as ((T5 (110 kg N ha-1> T4 (90 kg N ha-1> T3 (70 kg N ha-1> T2 (50 kg N ha_1> TControl) for all growth, yield and yield helping attributes such as plant height, number of grains spike-1, dry matter (kg ha-1), number of tillers plant-1, 1000-grain weight(g), grain yield (kg ha-1), spike length (cm), number of grains spikelet-1, number of spikelet spike-1, spike number m-2 and number of leaves plant_1. So, for obtaining aimed and desirable yield the application of (110 kg N ha-1) is recommended under research area conditions (Agro-Climatic Condition).
2020-21 年春季,在喀布尔大学农业研究农场进行了一项田间试验,研究不同氮素水平(0、50、70、90 和 110 kg N ha-1)对喀布尔农业气候条件下小麦(品种 Koshan-02)的生长、产量和产量相关参数的影响。试验采用随机完全区组设计(RCBD),设三个重复,每个重复由五个处理组成。处理总数为 15 个。每个小区的面积为(2mx3m=6m2)。研究结果表明,施用最高水平氮肥(110 千克/公顷-1)的地块株高最高(85.97 厘米),穗粒数最多(35.74 粒),干物质最高(3.937 吨/公顷-1)。937t ha-1)、最高分蘖数 m-2 (152.76 m-2)、千粒重 (48.94g)、谷物产量 (2891.1kg/ha)、大穗长 (10.52)、穗粒数-1 (2.98)、小穗数-1 (11.54),其次是 T4、T3 和 T2。株高、穗粒数-1、干物质(kg ha-1)、分蘖数-1、千粒重(g)、谷物产量(kg ha-1)、穗长(cm)、穗粒数-1、小穗数-1、穗粒数 m-2 和叶片数_1。因此,在研究地区的条件下(农业气候条件),建议施用(110 千克/公顷-1)氮肥,以获得目标产量和理想产量。
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引用次数: 0
Polymorphisms of IL-1B And IL-10 Genes in Abortion Due to Toxoplasmosis 弓形虫病所致流产中 IL-1B 和 IL-10 基因的多态性
Pub Date : 2024-04-23 DOI: 10.55544/jrasb.3.2.21
Basheer. Abd. Nasralla, Nazar Sh. Mohammed, Salwa S. Muhsen Muhsen
Ninety whole blood samples were collected from women attended Ibn-abalady Hospital/Baghdad city. 60 samples were taken from aborted women and 30 samples were taken from healthy women as a control group, from period 1st October 2022 to 2nd may 2023. According the results, the mean age of aborted women who attacked with toxoplasmois groups were 31.50 ±1.05 versus 34.53±2.09 of control groups with non-statistical differences (P-value=0.2). The results also observed the most cases of 3 (30.0%) among  aborted women were at the (27-36) years with 27/60 (73.0%) , while the less cases of  toxoplasmosis among  aborted women were at the age  > 46 years with 3/60 (30.0%),These differences statistically were non-significant (P-value=0.07). The results also observed there were equal cases of toxoplasmosis of women who habited urban and rural regions 30 /60 (66.7%),30 (66.7%) respectively. the levels of IgM (2.01±0.15, 0.13±0.03) and IgG (14.24±0.91, 0.09±0.02)  were higher in levels among pregnant women than control groups respectively, these differences in the levels was highly significant (p ≤0.001,≤ 0.001) respectively. the levels of  IL-IB (24.32±1.04, 4.64±0.36) and IL-10 (60.67±3.46, 5.61±0.36)  were higher in levels among aborted women than control groups respectively, these differences in the levels was highly significant. there were a significant differences in the levels of IgM () among aborted betwen the duration of pregnancy with P-value=0.03,Althogh the  the levels of IgG were  increased in levls among aborted women during the the first, second and third (14.40±1.41, 15.16±1.77, 12.86±1.62) above the normal range (≥1) respectively.  there were non  significant differences in the levels of both IL-1B  and IL-10   among aborted women during the the first, second and third simister although there were increased in the levels of both IL-1B  and IL-10.
从巴格达市伊本-阿巴拉迪医院(Ibn-abalady Hospital/Baghdad)就诊的妇女中采集了 90 份全血样本。从 2022 年 10 月 1 日至 2023 年 5 月 2 日,从流产妇女中采集了 60 份样本,从健康妇女中采集了 30 份样本作为对照组。结果显示,感染弓形体的流产妇女的平均年龄为(31.50±1.05)岁,而对照组的平均年龄为(34.53±2.09)岁,两者无统计学差异(P 值=0.2)。结果还发现,流产妇女中弓形虫病例数最多的年龄段为(27-36)岁,为 27/60(73.0%),而弓形虫病例数较少的年龄段为(46)岁以上,为 3/60(30.0%),这些差异无统计学意义(P 值=0.07)。IgM(2.01±0.15,0.13±0.03)和 IgG(14.24±0.91,0.09±0.02)水平孕妇组分别高于对照组,差异有显著性(P≤0.流产妇女 IL-IB(24.32±1.04,4.64±0.36)和 IL-10(60.67±3.46,5.61±0.36)水平分别高于对照组,差异有非常显著性(P≤0.001,≤0.001)。流产妇女的 IgM()水平在不同妊娠期有明显差异,P 值=0.03,但 IgG 水平在第一、第二和第三妊娠期(14.40±1.41、15.16±1.77、12.86±1.62)高于对照组。第一次、第二次和第三次流产妇女的 IL-1B 和 IL-10 水平均有所升高,但差异不显著。
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引用次数: 0
Effect of Enteric Fever on Hematological Cells Parameters 肠炎对血液细胞参数的影响
Pub Date : 2024-04-23 DOI: 10.55544/jrasb.3.2.22
Israrullah Rahimee, Mohammad Azim Azimee
Background: Salmonella typhoid and paratyphoid are the agents that cause Enteric fever (Typhoid fever). It is primarily a disease of developing countries because of poor sanitation standards. Fever is a prominent and well-known feature of the illness that increases steadily to a maximum degree. The hematological criteria of an affected individual are changed by this infectious disease. To ascertain the different hematological cells parameters in our sample population, we conducted the investigation. Patients and Methodology: The study, which involved 100 Afghans, was carried out at the Nangarhar University Teaching Hospital between June and November of 2022. A case-control study design was used. Fifty individuals (Cases) who had a confirmed diagnosis of Enteric fever (Typhoid fever) based on typhoid (IgG and IgM) were included in the study. As a control group, fifty healthy individuals with negative typhoid (IgG and IgM) results and no other complaints were included in the study. For both the case and control groups, a complete blood count was performed. Hemoglobin (Hb), White Blood Cell Count (WBC), and Platelet Count (PLT) are regarded as hematological markers. Every patient was also interviewed, and a questionnaire was employed. Numerous demographic factors were questioned, including sex, age, economic status, level of education, and clinical symptoms. SPSS version 16 was then used to analyze the collected data. Results. In the current research, over all 100 patients were enrolled (50 were case, and 50 were control group). The mean age± SD of the patients under the study were 38.74±15.22 years. The most common hematological changes observed were; anemia (32%), thrombocytopenia (24%), leukocytosis (8%) & leucopenia (22%). Fever was the most common presenting symptom (78%) and abdominal symptoms were about 38%. Most of the people were of lower socioeconomic state and were uneducated. Conclusion: This study shows that Enteric fever is bacterial infection and are acquired by enteral route. This disease commonly affects people of low socioeconomical states and those that are uneducated. Fever was the most commonly presenting symptom in these patients. Enteric fever causes changes in the hematological cells parameters which is probably due to bone marrow suppression, which is transient and shows response to therapy.
背景:伤寒沙门氏菌和副伤寒沙门氏菌是引起肠炎(伤寒)的病原体。由于卫生条件差,伤寒主要是发展中国家的一种疾病。发热是该病众所周知的一个显著特征,发热会持续上升到最高程度。这种传染病会改变患者的血液学标准。为了确定样本人群的不同血液细胞参数,我们进行了调查。患者和方法:这项研究涉及 100 名阿富汗人,于 2022 年 6 月至 11 月期间在楠格哈尔大学教学医院进行。采用病例对照研究设计。研究纳入了 50 名根据伤寒(IgG 和 IgM)确诊为肠道热(伤寒)的患者(病例)。作为对照组,50 名伤寒(IgG 和 IgM)检测结果为阴性且无其他不适症状的健康人被纳入研究。病例组和对照组均进行了全血细胞计数。血红蛋白(Hb)、白细胞计数(WBC)和血小板计数(PLT)被视为血液学指标。此外,还对每位患者进行了访谈,并采用了调查问卷的形式。问卷调查了许多人口统计学因素,包括性别、年龄、经济状况、教育程度和临床症状。然后使用 SPSS 16 版对收集到的数据进行分析。结果本次研究共招募了 100 多名患者(其中 50 人为病例组,50 人为对照组)。研究对象的平均年龄(38.74±15.22)岁。最常见的血液学变化是贫血(32%)、血小板减少(24%)、白细胞增多(8%)和白细胞减少(22%)。发热是最常见的症状(78%),腹部症状约占 38%。大多数人社会经济地位较低,未受过教育。结论这项研究表明,肠热病是一种细菌感染,通过肠道途径感染。这种疾病通常影响社会经济地位较低和未受过教育的人群。发热是这些患者最常见的症状。肠热病会导致血液细胞参数发生变化,这可能是由于骨髓抑制所致,但这种抑制是短暂的,而且会对治疗产生反应。
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引用次数: 0
Susceptibility of Staphylococcus spp. to the Plant Crude Extract 葡萄球菌对植物粗萃取物的敏感性
Pub Date : 2024-04-19 DOI: 10.55544/jrasb.3.2.20
Sulaiman Dawod Daowd, Haider Hamid Khudiar, Tiba Ayad Ahmed Sezae
The study aimed to investigate whether the extract from the Thuja orientalis plant had any antibacterial properties against fifteen MRSA isolates in a group of thirty-seven Staphylococcus aureus isolates. To determine bacterial resistance, an antibiotic susceptibility test was conducted on five different drugs. Methicillin showed the highest level of bacterial resistance (100%), whereas Vancomycin had the lowest level of resistance (6.6%). The results of the examination of the Thuja orientalis plant extract clearly showed that it had a significant suppressive effect on all Staphylococcus aureus isolates.
该研究旨在调查从东方侧柏植物中提取的提取物是否对一组 37 个金黄色葡萄球菌分离物中的 15 个 MRSA 分离物具有抗菌特性。为了确定细菌的耐药性,对五种不同的药物进行了抗生素药敏试验。结果显示,甲氧西林的细菌耐药性最高(100%),而万古霉素的耐药性最低(6.6%)。东方侧柏植物提取物的检测结果清楚地表明,它对所有分离出的金黄色葡萄球菌都有显著的抑制作用。
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引用次数: 0
The Optimal LD50 Gamma Ray and Sodium Azide-Induced Mutagenesis in the PBNS-86 Variety Safflower 伽马射线和叠氮化钠诱导红花 PBNS-86 品种突变的最佳半数致死剂量
Pub Date : 2024-04-16 DOI: 10.55544/jrasb.3.2.19
Shafique Mirza, S. E. Mahamune, S. B. Thorat
Safflower has been grown for millennia all over the world, making it one of the most important and ancient oil-producing crops. In this work, we use gamma rays and sodium azide at LD50 levels to target high-yielding and desirable characters. The safflower variety PBNS-86 seeds were subjected to varying quantities of sodium azide (0.005%, 0.010%,0.015%,0.020% and 0.025%) and gamma-ray treatments at levels of 100Gy, 200Gy, 300Gy, 400Gy and 500Gy. The carcinogenic administrations of sodium azide and gamma rays had a detrimental dose-dependent association with the plant survival percentage in the PBNS-86 variety. The anticipated LD50 value was calculated using probit values and fatality percentages. For gamma rays and sodium azide, the LD50 value of PBNS-86 was set at 296.2 Gy and 0.1513%, respectively. The greatest reduction in the proportion of plants that survived was induced by gamma rays and sodium azide treatments. It is determined that both mutagens are capable of causing notable changes in safflower, which may be investigated further for the purpose of mutation mapping.
红花在世界各地已有数千年的种植历史,是最重要、最古老的产油作物之一。在这项研究中,我们利用伽马射线和叠氮化钠(LD50 水平)针对高产和理想的特征进行研究。对红花品种 PBNS-86 种子施加了不同剂量的叠氮化钠(0.005%、0.010%、0.015%、0.020% 和 0.025%)和伽马射线处理,处理水平分别为 100Gy、200Gy、300Gy、400Gy 和 500Gy。叠氮化钠和伽马射线的致癌作用与 PBNS-86 品种的植物存活率呈剂量依赖关系。预期半数致死剂量值是利用概率值和致死率计算得出的。伽马射线和叠氮化钠对 PBNS-86 的半数致死剂量分别设定为 296.2 Gy 和 0.1513%。在伽马射线和叠氮化钠处理中,存活植物比例的降低幅度最大。可以确定,这两种诱变剂都能使红花发生显著变化,可进一步研究,以绘制突变图谱。
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引用次数: 0
Effect of Precision Application of Nutrients on, Growth, Yield, Quality and Nutrient Use Efficiency in Tomato (Solanum lycopersicum L.) Cv. Pearson 精确施用养分对番茄(Solanum lycopersicum L.)Cv.生长、产量、品质和养分利用效率的影响皮尔逊
Pub Date : 2024-04-16 DOI: 10.55544/jrasb.3.2.18
Hekmatullah Zaland, Aimal Nahiz, Mohammad Yar Malakzai, Saifullah Mangal
The investigation was conducted to study the Effect of precision application of nutrients on yield, quality and nutrient use efficiency in tomato (cv. Pearson). The experiment was carried out at Bolan Research Farm, Helmand, Afghanistan during the year 2021.  The experiment was laid out in (RCBD) designed having three replications, each replication consisted of 10 treatments. The treatments comprised of T1: Fertilizers Urea + DAP + MOP (140:60:60 kg/ha), T2: Fertilizers Urea + DAP + MOP (70:30:30 kg/ha), T3: Fertilizers + Nutrient Solution Urea + DAP + MOP + NPK + Urea (70:30:30 + 70:30:30), T4: Fertilizers + Nutrient Solution Urea + DAP + MOP + MAP + Urea + MOP (70:30:30 + 70:30:30), T5: Fertilizers + Nutrient Solution Urea + DAP + MOP + NPK + Urea (70:30:30 + 55:24:24), T6: Fertilizers + Nutrient Solution Urea + DAP + MOP + VAM MAP + Urea + MOP (70:30:30 + 55:24:24), T7: Fertilizers + Nutrient Solution Urea + DAP + MOP + NPK + Urea (70:30:30 + 42:18:18), T8: Fertilizers + Nutrient Solution Urea + DAP + MOP + VAM MAP + Urea + MOP (70:30:30 + 42:18:18), T9: RDF Urea + DAP + MOP (137.5:62.5:60) and T10: Control (No fertilizer). The result confirmed that integrated application of nutrient significantly affected all growth, yield and yield traits of tomato hence, the tallest plant (133.33cm), maximum No. of branches plant-1 (31.67), No. of fruit plant-1 (67.33), large polar diameter (8.33cm), large equatorial diameter (8.33cm), average yield plant-1(6.13 kg), total yield (344.00 q/ha), total soluble content (4.61 %), dry matter content (5.02%) were recorded in the plots were treated with T8 (Urea + DAP + MOP + VAM MAP + Urea + MOP) (70:30:30 + 42:18:18) except the fruits weight(g) and average fruit weight (g) as compared to other treated plots,. Generally, all fertilized plots showed positive & better performance as compared to control plots (no treated plots). We concluded from the result that all treatments regarding their efficient effect and economical use were ranked as (T8> T9> T7> T6> T5> T4> T3> T2> T1> TControl) for all growth, yield and yield characters of tomato (cv. Pearson) in research area.
这项调查旨在研究精准施用养分对番茄产量、品质和养分利用效率的影响。实验于 2021 年在阿富汗赫尔曼德省的博兰研究农场进行。 试验采用 (RCBD) 设计,有三个重复,每个重复由 10 个处理组成。处理包括 T1:肥料尿素 + DAP + MOP(140:60:60 千克/公顷),T2: 肥料尿素 + DAP + MOP(70:30:30 千克/公顷),T3:肥料 + 营养液尿素 + DAP + MOP + NPK + 尿素(70:30:30 + 70:30:30),T4:肥料+营养液尿素+磷酸二铵+澳门美高梅国际娱乐平台+澳门美高梅国际娱乐平台+尿素+澳门美高梅国际娱乐平台(70:30:30+70:30:30),T5:肥料+营养液尿素+磷酸二铵+澳门美高梅国际娱乐平台+氮磷钾+尿素(70:30:30+55:24:24),T6:肥料+营养液尿素+磷酸二铵+澳门美高梅国际娱乐平台+VAM澳门美高梅国际娱乐平台+尿素+澳门美高梅国际娱乐平台(70:30:30+55:24:24),T7:肥料+营养液尿素+磷酸二铵+澳门美高梅国际娱乐平台+NPK+尿素(70:30:30+42:18:18),T8:肥料+营养液尿素+磷酸二铵+澳门美高梅国际娱乐平台+VAM澳门美高梅国际娱乐平台+尿素+澳门美高梅国际娱乐平台(70:30:30+42:18:18),T9:RDF尿素+磷酸二铵+澳门美高梅国际娱乐平台(137.5:62.5:60),T10:对照(不施肥)。结果表明,综合施肥对番茄的所有生长、产量和性状都有显著影响,最高植株(133.33 厘米)、最大分枝数(31.67)、果实数(67.33)、大极径(8.33 厘米)、大赤道径(8.33 厘米)、平均单株产量(6.13 kg)、总产量(344.00 q/ha)、可溶性总含量(4.61 %)、干物质含量(5.02 %),与其他施肥地块相比,T8(尿素 + DAP + MOP + VAM MAP + 尿素 + MOP)(70:30:30 + 42:18:18)地块的果实重量(g)和平均果实重量(g)均有所提高。总体而言,与对照地块(未施肥地块)相比,所有施肥地块都表现出积极和更好的表现。研究结果表明,在番茄(变种皮尔逊)的所有生长、产量和收益特征方面,所有处理的有效效果和经济效益排名为(T8> T9> T7> T6> T5> T4> T3> T2> T1> TC 对照)。
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引用次数: 0
Review of Virulence Factors in Candida 念珠菌毒性因子综述
Pub Date : 2024-04-13 DOI: 10.55544/jrasb.3.2.15
Mohammed Sami Farhan, Bilal Ahmed Abdullah, Ali Esam Mamdwooh, Rand Salwan Numan
Candida albicans is a prevalent commensal fungus that inhabits various anatomical regions, including the oropharyngeal cavity, gastrointestinal and vaginal tract, as well as the skin of persons in good condition. C. albicans is present in the normal flora of the microbiota in around 50% of the population. The clinical presentations of Candida species encompass a spectrum of symptoms, spanning from localized. The spectrum of mucocutaneous issues ranges from superficial to invasive disorders that impact many organ systems and present a substantial threat to human life. Disruptions in the normal homeostasis of Candida can be attributed to a range of reasons, encompassing systemic and local factors as well as genetic and environmental influences. These disruptions ultimately lead to a shift from a state of normal flora to the development of Infections caused by pathogens and opportunistic agents. The initiation and advancement of infection are regulated by the virulence characteristics of Candida, which play a role in the emergence of candidiasis. Oral candidiasis presents with a wide range of symptoms, which can be classified into major and minor types. The gastrointestinal tract is the main reservoir for Candida albicans in the human body. Infection occurs due to an imbalance in the local microbiota, impaired immune function, and damage to the intestinal mucosal barrier. Candidaemia, a term used to describe invasive infections caused by candida, is associated with the presence of Candida albicans in the bloodstream. The mutual relationship remains intact by maintaining a balance between the host immune system and C. albicans virulence factors. This study investigates the virulence traits exhibited by Candida albicans. These components have a significant impact on the development of disorders.
白色念珠菌是一种普遍存在的共生真菌,栖息于各种解剖区域,包括口咽腔、胃肠道和阴道,以及状况良好者的皮肤。白念珠菌存在于约 50%人群的正常微生物群中。白色念珠菌的临床表现包括一系列症状,从局部症状到全身症状。皮肤粘膜问题的范围从浅表性到侵袭性疾病不等,这些疾病会影响许多器官系统,对人类生命构成严重威胁。念珠菌正常平衡的破坏可归因于一系列原因,包括系统和局部因素以及遗传和环境影响。这些干扰最终导致正常菌群状态转变为由病原体和机会性病原体引起的感染。感染的发生和发展受念珠菌毒力特性的调节,而念珠菌毒力特性在念珠菌病的发生中起着重要作用。口腔念珠菌病的症状多种多样,可分为主要类型和次要类型。胃肠道是人体中白色念珠菌的主要贮藏地。感染发生的原因包括局部微生物群失衡、免疫功能受损以及肠粘膜屏障受损。念珠菌血症是指由念珠菌引起的侵袭性感染,与血液中存在的白色念珠菌有关。通过维持宿主免疫系统和白念珠菌毒力因子之间的平衡,这种相互关系保持不变。本研究调查了白色念珠菌表现出的毒力特征。这些成分对疾病的发展有重大影响。
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引用次数: 0
Analyzing the Time Evolution of a Particle by Decomposes the Initial State Confinement in 1D Well into the Lowest Eigenstates Energy 通过将一维井中的初始态禁锢分解为最低特征态能量来分析粒子的时间演化
Pub Date : 2024-04-13 DOI: 10.55544/jrasb.3.2.17
M. Oglah
In this work, we obtained the time evolution of the wave function of a limited quantum system (1D Box), hence getting a mathematical model to describe the system. By using programming computes, it performs a time evolution that decomposes the initial state into the 2,10, and 20 lowest energy eigenstates. Finally, by comparing numerical de-composition coefficients for the wave function to the analytical values, it found the number of knots increases directly versus the energy of the particle's quantum state. As a result, the mean bending given by the second derivative which is proportional to the kinetic energy operator should increase. We found there is a negligible mean and standard deviation of the energy in units of the ground state energy.
在这项工作中,我们获得了有限量子系统(1D Box)波函数的时间演化,从而得到了描述该系统的数学模型。通过编程计算,它执行了时间演化,将初始状态分解为 2、10 和 20 个能量最低的特征状态。最后,通过比较波函数的数值分解系数和分析值,它发现结的数量会随着粒子量子态能量的增加而直接增加。因此,与动能算子成正比的二阶导数给出的平均弯曲度应该增加。我们发现,以基态能量为单位的能量平均值和标准偏差可以忽略不计。
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引用次数: 0
Role of Herbal Active Compound in Cardiac Failure Treatment 草药活性成分在心力衰竭治疗中的作用
Pub Date : 2024-04-13 DOI: 10.55544/jrasb.3.2.16
Jyotsna Upadhyay, Amle Vandana Sonaji, Khonde Shital Trimbak, Chapke Seema Ganesh, Kisan Vivek Pawar, Anamika, Roshan Kumar
The prevalence of cardiovascular diseases (CVDs) is constantly rising, making them a major health burden. In terms of global mortality and morbidity, they are still at the top. An alternate method of treating many illnesses, including CVDs, is the use of medicinal herbs. There is a current, unprecedented push to include herbal remedies into contemporary healthcare systems. The widespread conviction in their safety and the fact that they offer more effective treatment at a lower cost than conventional modern medicines are two of the main factors propelling this movement. However, there has not been enough testing of the purported safety of herbal remedies. As a result, people need to know that medical herbs can be toxic, have possibly fatal side effects, and can interact negatively with other drugs. Experimental evidence suggests that medicinal herbs may be useful in the treatment of cardiovascular diseases (CVDs) due to their ability to inhibit multiple risk factors for these conditions. So, in order to successfully use herbs in CVD therapy, there have been numerous initiatives to transition medicinal herb research from the lab to the clinic. Presented below are cardiovascular diseases (CVDs) and the variables that put people at risk for developing them. Next, we provide a synopsis of herbal medicine's role in the treatment of disease, with a focus on cardiovascular diseases. In addition, information is compiled and examined about the ethnopharmacological therapeutic possibilities and medicinal qualities against cardiovascular diseases of four commonly used plants: ginseng, gingko biloba, ganoderma lucidum, and gymnostemma pentaphyllum. The use of these four plants in the treatment of cardiovascular diseases (CVDs) including myocardial infarction, hypertension, peripheral vascular disorders, coronary heart disease, cardiomyopathies, and dyslipidemias has been well examined. We are also making an effort to describe the current in vitro and in vivo investigations that have attempted to examine the cellular and molecular underpinnings of the four plants' cardio-protective effects. Lastly, we highlighted the effectiveness, safety, and toxicity of these four medicinal herbs by reviewing and reporting the results of current clinical trials. GRAPHICAL ABSTRACT  
心血管疾病(CVDs)的发病率持续上升,成为主要的健康负担。就全球死亡率和发病率而言,心血管疾病仍居首位。治疗包括心血管疾病在内的许多疾病的另一种方法是使用药草。目前,人们正前所未有地推动将草药疗法纳入当代医疗保健系统。人们普遍相信草药的安全性,而且与传统现代药物相比,草药能以更低的成本提供更有效的治疗,这是推动这一运动的两个主要因素。然而,对草药所谓的安全性还没有进行足够的测试。因此,人们需要知道,草药可能有毒,可能有致命的副作用,还可能与其他药物产生不良反应。实验证据表明,由于草药能够抑制心血管疾病(CVDs)的多种危险因素,因此可能有助于治疗这些疾病。因此,为了成功地将草药用于心血管疾病的治疗,已经有许多倡议将药草研究从实验室转向临床。下面介绍心血管疾病(CVD)以及导致人们面临患病风险的各种变量。接下来,我们将简要介绍草药在治疗疾病方面的作用,重点是心血管疾病。此外,我们还汇编并研究了四种常用植物(人参、银杏叶、灵芝和五味子)的民族药理学治疗可能性和对心血管疾病的药用价值。这四种植物在治疗心血管疾病(CVDs)(包括心肌梗塞、高血压、外周血管疾病、冠心病、心肌病和血脂异常)方面的应用已得到充分研究。我们还努力描述了目前试图研究这四种植物心血管保护作用的细胞和分子基础的体外和体内研究。最后,我们通过回顾和报告目前的临床试验结果,强调了这四种药材的有效性、安全性和毒性。图表摘要
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Journal for Research in Applied Sciences and Biotechnology
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