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Development of a method for measuring active outdoor play in preschool-aged children: Integrating accelerometer, GPS, and time-use diary data. 开发一种测量学龄前儿童户外活动的方法:整合加速度计、GPS和时间使用日记数据。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-23 DOI: 10.1016/j.amepre.2025.108242
Yeongho Hwang, John C Spence, Louise C Mâsse, Valerie Carson

Introduction: Current physical activity (PA) measurement methods often fail to capture domain-specific contexts. This limitation hinders the understanding of active outdoor play (AOP) in preschool-aged children (3-5 years), a critical PA domain for healthy development. The primary objective of this study was to develop a method for measuring AOP by integrating accelerometer, Global Positioning System (GPS), and time-use diary data. The secondary objective was to apply this method to quantify AOP by movement intensity and examine its contribution to total PA.

Methods: This cross-sectional study included 92 preschool-aged children and their parents from Alberta, Canada. Data were collected in August/2023-February/2024 and analyzed in May/2024-February/2025. Children wore an accelerometer and a GPS monitor for 7 days, while parents completed a time-use diary documenting their child's daily activities. Data from these 3 sources were processed and integrated to derive AOP variables. AOP was operationally defined as non-trip and non-organized PA taking place outdoors. Accelerometer data classified PA versus stationary time. GPS data classified trip versus non-trip and indoor versus outdoor location. Time-use diary data classified organized versus non-organized PA. AOP engagement was further classified into light-intensity and moderate- to vigorous-intensity using accelerometer data.

Results: Applying this method to the present sample, children spent an average of 192.9 minutes/day in AOP, with 143.1 minutes/day in light-intensity and 49.8 minutes/day in moderate- to vigorous-intensity AOP. On average, AOP accounted for 60.6% of total PA.

Conclusions: This study introduced a multi-source method for measuring AOP in preschool-aged children, addressing key limitations of traditional single-source methods. Future research could explore this method's applicability to enhance domain-specific PA knowledge, beyond overall PA, across contexts.

当前的物理活动(PA)测量方法常常不能捕获特定领域的上下文。这一限制阻碍了对学龄前儿童(3-5岁)积极户外游戏(AOP)的理解,这是健康发展的关键PA域。本研究的主要目标是开发一种通过集成加速度计、全球定位系统(GPS)和时间使用日记数据来测量AOP的方法。第二个目标是应用该方法通过运动强度来量化AOP,并检查其对总PA的贡献。方法:本横断面研究包括来自加拿大阿尔伯塔省的92名学龄前儿童及其父母。数据收集于2023年8月至2024年2月,分析于2024年5月至2025年2月。孩子们戴着加速度计和GPS监视器7天,而父母则完成一份记录孩子日常活动的时间使用日记。对来自这3个源的数据进行处理和集成,以派生AOP变量。AOP在操作上被定义为发生在户外的非旅行和非组织的PA。加速度计数据分类PA与静止时间。GPS数据分类旅行与非旅行和室内与室外的位置。分类有组织与无组织PA的时间使用日记数据。使用加速度计数据进一步将AOP参与分为轻度强度和中度到剧烈强度。结果:将该方法应用于本样本,儿童在AOP上的平均花费为192.9分钟/天,其中低强度AOP为143.1分钟/天,中高强度AOP为49.8分钟/天。平均而言,AOP占总PA的60.6%。结论:本研究介绍了一种多来源的方法来测量学龄前儿童的AOP,解决了传统单一来源方法的主要局限性。未来的研究可以探索这种方法的适用性,以增强特定领域的PA知识,超越整体PA,跨上下文。
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引用次数: 0
Primary Care–Based Alcohol Screening and Alcohol Use Among Transgender and Cisgender Adults in an Integrated Health System 综合卫生系统中跨性别和顺性别成人中基于初级保健的酒精筛查和酒精使用
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-23 DOI: 10.1016/j.amepre.2025.108240
Shannon He MD , Riley Darby-McClure MD , Matthew E. Hirschtritt MD, MPH , Stacy A. Sterling DrPH, MSW, MPH , Michael J. Silverberg PhD, MPH , Wendy A. Leyden MPH , Alan H. Shu MD , Toren S. Andrewson MS , Vanessa A. Palzes MPH

Introduction

Alcohol screenings and excessive alcohol use among transgender adults remain understudied. Prior research is limited by small samples, poor generalizability, and lack of validated gender identity data. This study examined alcohol screening rates and excessive use among transgender and cisgender adult members of a large, integrated health system.

Methods

Electronic health record data from Kaiser Permanente Northern California (2013–2021) were analyzed. Gender identity was previously verified. Primary outcomes included completion of a standardized alcohol screening over a 2-year follow-up and alcohol use exceeding national sex- and age-based limits. Concordance between screening parameters and sex assigned at birth versus gender identity was explored.

Results

Of the 7,933 transgender and 128,577 cisgender adults studied, 76% and 66% received alcohol screening, respectively. Transgender individuals had higher alcohol screening rates (adjusted hazard ratio=1.08; 95% CI=1.05, 1.11), and 68.3% were screened using drinking limits based on sex assigned at birth. Among those screened, excessive alcohol use was lower among transgender individuals (8.2% vs 10.6%; adjusted prevalence ratio=0.85; 95% CI=0.78, 0.93). Prevalence of excessive alcohol use was similar regardless of whether screening parameters aligned with sex assigned at birth or gender identity.

Conclusions

Transgender individuals were more likely to receive alcohol screening, and those screened had lower prevalence of excessive alcohol use than cisgender comparators. This study adds to the limited literature on how transgender populations are screened in a real-world clinical setting and may inform future alcohol screening practices and guideline development.
酒精筛查与跨性别成人过度饮酒的关系仍未得到充分研究。先前的研究受限于样本小、普遍性差和缺乏有效的性别认同数据。本研究调查了大型综合卫生系统中跨性别和顺性别成年成员的酒精筛查率和过度使用。方法:分析北加州凯撒医疗机构2013-2021年的电子健康记录数据。性别身份先前已得到核实。主要结果包括在2年随访期间完成标准化酒精筛查和酒精使用超过国家基于性别和年龄的限制。筛选参数和出生性别与性别认同之间的一致性进行了探讨。结果:在7933名变性人和128577名顺性成年人中,分别有76%和66%的人接受了酒精筛查。跨性别者的酒精筛查率更高(aHR, 1.08; 95% CI, 1.05-1.11), 68.3%的人根据出生时指定的性别进行了酒精筛查。在接受筛查的人群中,跨性别者过度饮酒的比例较低(8.2% vs 10.6%; aPR, 0.85; 95% CI, 0.78-0.93)。无论筛查参数是否与出生时的生理性别或性别认同相符,过度饮酒的流行程度都是相似的。结论:变性人更有可能接受酒精筛查,而接受筛查的人过度饮酒的患病率低于顺性别比较者。这项研究补充了关于如何在现实世界的临床环境中对跨性别人群进行筛查的有限文献,并可能为未来的酒精筛查实践和指南的制定提供信息。
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引用次数: 0
Colorectal cancer screening among non-colorectal cancer survivors: a systematic review and meta-analysis. 非结直肠癌幸存者的结直肠癌筛查:系统回顾和荟萃分析。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-23 DOI: 10.1016/j.amepre.2025.108239
Sanjeev Bista, Momtafin Khan, Rey Nambayan, Marcus Vaska, Yibing Ruan, Robert J Hilsden, Darren R Brenner, Dylan E O'Sullivan

Introduction: This study aimed to determine the prevalence of colorectal cancer (CRC) screening among cancer survivors and compare the likelihood of CRC screening among cancer survivors to that of the cancer-free general population.

Methods: A systematic search of MEDLINE (Ovid), EMBASE, PubMed, and CINAHL databases from inception through September 16, 2024 was conducted. Studies reporting CRC screening among cancer survivors or in both cancer survivors and cancer-free controls were included. Random effects meta-analyses were conducted to pool estimates. Analyses were performed across primary cancer sites where at least three studies were identified.

Results: Of the 2497 articles identified, 59 fulfilled the inclusion criteria. The overall pooled prevalence of CRC screening (up-to-date for screening or had been screened during a specific time period after non-CRC diagnosis) was 0.53 (95% CI: 0.46, 0.61), with estimates ranging from 0.72 (prostate) to 0.51 (breast) across primary cancer sites. Cancer survivors were more likely to participate in CRC screening than cancer-free controls (Odds Ratio: 1.39, 95%CI: 1.26, 1.52), but there was some evidence of publication bias (Egger's test p-value = 0.092). Study design, method of CRC screening ascertainment (self-report vs. medical records), and first primary cancer site were significant sources of heterogeneity.

Discussion: Cancer survivors were more likely to undergo CRC screening compared to cancer-free controls, but overall rates were well below generally recommended levels for population-based screening. Future studies should evaluate the predictors of non-adherence to CRC screening among cancer survivors to inform policymakers in targeting populations with lower screening rates.

本研究旨在确定结直肠癌(CRC)筛查在癌症幸存者中的流行程度,并比较癌症幸存者与无癌症普通人群中CRC筛查的可能性。方法:系统检索MEDLINE (Ovid)、EMBASE、PubMed、CINAHL数据库自成立至2024年9月16日。报告在癌症幸存者或癌症幸存者和无癌症对照中进行结直肠癌筛查的研究被纳入。随机效应荟萃分析用于汇总估计。在原发癌症部位进行了分析,其中至少有三个研究被确定。结果:共纳入2497篇文献,59篇符合纳入标准。CRC筛查(最新筛查或在非CRC诊断后的特定时间段内进行筛查)的总体合并患病率为0.53 (95% CI: 0.46, 0.61),原发癌部位的估计值从0.72(前列腺)到0.51(乳腺癌)不等。癌症幸存者比无癌症对照者更有可能参加结直肠癌筛查(优势比:1.39,95%CI: 1.26, 1.52),但有一些证据表明存在发表偏倚(Egger检验p值 = 0.092)。研究设计、CRC筛查确定方法(自我报告与医疗记录)和第一原发癌部位是异质性的重要来源。讨论:与无癌对照相比,癌症幸存者更有可能接受结直肠癌筛查,但总体比率远低于一般推荐的基于人群的筛查水平。未来的研究应该评估癌症幸存者不坚持CRC筛查的预测因素,以告知决策者针对筛查率较低的人群。
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引用次数: 0
Did Increases in SNAP Benefits from the Emergency Allotments and Thrifty Food Plan Modernization Shift Grocery Purchase Quality in North Carolina? 来自紧急拨款和节俭食品计划现代化的SNAP福利的增加是否改变了北卡罗来纳州的杂货采购质量?
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-23 DOI: 10.1016/j.amepre.2025.108247
Alexandra Ross, Shu Wen Ng

Introduction: The federal Supplemental Nutrition Assistance Program (SNAP) seeks to improve food and nutritional security, but pre-pandemic evidence suggests benefit amounts are insufficient. Pandemic-related Emergency Allotments (EA) and Thrifty Food Plan Modernization (TFPM) increased SNAP benefit amounts. This study uses transaction data from shoppers at a large supermarket chain in North Carolina to understand if these changes were associated with shifts in grocery food purchase composition.

Methods: Data was collected from October 2019-February 2022 and analyzed from October-November 2023. A difference-in-differences approach was applied to assess purchase changes among a matched panel of SNAP and non-SNAP shoppers before and after the EA and TFPM and compared to the pre-pandemic period.

Results: Higher increases in fruits, vegetables, nuts, legumes, and other non-processed foods and beverages purchases were observed among SNAP shoppers (vs. non-SNAP shoppers) after the implementation of both the EA and TFPM. Decreases in sugar-sweetened beverages purchased and sugar from purchases after the EA were also observed. Purchase improvements were more notable when both EA and TFPM benefits were applied.

Conclusions: Even modest SNAP benefit increases were associated with purchase changes, suggesting benefit amounts have a key role in improving purchase composition. With the expiration of emergency allotments in 2023 and upcoming debates around the SNAP program, understanding the implications of benefit adequacy on food purchasing remains critical for policy planning. These findings provide timely evidence on how SNAP enhancements may improve nutritional quality, underscoring the need to sustain or expand benefit levels to support healthy eating among low-income households.

简介:联邦补充营养援助计划(SNAP)旨在改善食品和营养安全,但大流行前的证据表明,福利金额不足。与流行病有关的紧急拨款(EA)和节俭食品计划现代化(TFPM)增加了SNAP的福利数额。这项研究使用了来自北卡罗来纳州一家大型连锁超市购物者的交易数据,以了解这些变化是否与杂货食品购买构成的变化有关。方法:采集时间为2019年10月- 2022年2月,分析时间为2023年10月- 11月。采用了差异中的差异方法来评估EA和TFPM前后匹配的SNAP和非SNAP购物者小组之间的购买变化,并与大流行前时期进行了比较。结果:在EA和TFPM实施后,在SNAP购物者中(与非SNAP购物者相比)观察到水果、蔬菜、坚果、豆类和其他非加工食品和饮料的购买量增加。在EA之后,购买的含糖饮料和购买的糖也有所减少。当EA和TFPM效益同时应用时,购买改进更为显著。结论:即使是适度的SNAP福利增加也与购买变化有关,这表明福利金额在改善购买构成方面起着关键作用。随着2023年紧急拨款到期,以及围绕SNAP计划即将展开的辩论,了解福利充足性对食品采购的影响对于政策规划仍然至关重要。这些发现及时提供了证据,说明强化SNAP如何改善营养质量,强调需要维持或扩大福利水平,以支持低收入家庭的健康饮食。
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引用次数: 0
Natural Transitions of Non–High-Density Lipoprotein Cholesterol Levels in Children Aged 9–11 Years 9-11岁儿童非高密度脂蛋白胆固醇水平的自然转变。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-23 DOI: 10.1016/j.amepre.2025.108243
Yaxing Meng PhD , Tetsuhiro Kidokoro PhD , Natsuko Imai PhD , Russell J. Thomson PhD , Grant R. Tomkinson PhD , Costan G. Magnussen PhD

Introduction

U.S. guidelines recommend universal lipid screening in children aged between 9 and 11 years, with follow-up screening at ages 17–21 years. Non–high-density lipoprotein cholesterol is the preferred marker. However, the stability of non–high-density lipoprotein cholesterol within the screening window remains unclear. This study aimed to estimate the probabilities of non–high-density lipoprotein cholesterol transitioning between its classifications (acceptable, borderline high, and high) during the 9–11-year age period and the average duration that it remains stable within each classification.

Methods

This study included 496 Japanese children with non–high-density lipoprotein cholesterol measured between ages 9 and 11 years. Data were collected from 2015 to 2019, and analyses were conducted in 2024. A time-homogeneous continuous-time Markov model was used to estimate the probabilities of transitioning among non–high-density lipoprotein cholesterol classifications—acceptable (<120 mg/dL), borderline high (120-144 mg/dL), and high (≥145 mg/dL)—and the average duration children remained in a given non–high-density lipoprotein cholesterol classification before transitioning.

Results

At the population level, all non–high-density lipoprotein cholesterol classifications identified at age 9 years were estimated to remain stable for more than 2 years. Children with acceptable non–high-density lipoprotein cholesterol had a mean duration of 10.6 years (95% CI=7.8, 14.5) before transitioning to another classification, with an estimated 0.90 probability of maintaining in the acceptable classification during the 9–11-year window.

Conclusions

Non–high-density lipoprotein cholesterol classifications identified at age 9 years remained stable for over 2 years, supporting the appropriateness of screening at any point within the 9–11-year window. These findings offer insights into optimal lipid-screening practices, thereby enhancing early cardiovascular disease prevention.
美国指南建议对9-11岁的儿童进行普遍的脂质筛查,并对17-21岁的儿童进行随访筛查。非高密度脂蛋白-胆固醇(non-HDL-C)是首选的标志物。然而,非hdl - c在筛查窗口内的稳定性仍不清楚。本研究旨在估计9-11岁期间非hdl - c在其分类(可接受、高边缘和高)之间转换的概率,以及在每个分类中保持稳定的平均持续时间。方法:本研究包括496名日本9 - 11岁非hdl - c儿童。数据收集于2015年至2019年,并于2024年进行分析。使用时间齐次连续时间马尔可夫模型来估计非hdl - c可接受分类之间转换的概率(结果:在人群水平上,所有在9岁时确定的非hdl - c分类估计保持稳定超过两年。可接受的非hdl - c儿童在转变为另一种分类之前的平均持续时间为10.6年(95%可信区间:7.8-14.5),在9-11年的窗口期,维持在可接受分类的概率估计为0.90。结论:9岁时确定的非hdl - c分类在两年内保持稳定,支持在9-11年窗口内任何时间进行筛查的适宜性。这些发现为最佳脂质筛查实践提供了见解,从而加强了早期心血管疾病的预防。
{"title":"Natural Transitions of Non–High-Density Lipoprotein Cholesterol Levels in Children Aged 9–11 Years","authors":"Yaxing Meng PhD ,&nbsp;Tetsuhiro Kidokoro PhD ,&nbsp;Natsuko Imai PhD ,&nbsp;Russell J. Thomson PhD ,&nbsp;Grant R. Tomkinson PhD ,&nbsp;Costan G. Magnussen PhD","doi":"10.1016/j.amepre.2025.108243","DOIUrl":"10.1016/j.amepre.2025.108243","url":null,"abstract":"<div><h3>Introduction</h3><div>U.S. guidelines recommend universal lipid screening in children aged between 9 and 11 years, with follow-up screening at ages 17–21 years. Non–high-density lipoprotein cholesterol is the preferred marker. However, the stability of non–high-density lipoprotein cholesterol within the screening window remains unclear. This study aimed to estimate the probabilities of non–high-density lipoprotein cholesterol transitioning between its classifications (acceptable, borderline high, and high) during the 9–11-year age period and the average duration that it remains stable within each classification.</div></div><div><h3>Methods</h3><div>This study included 496 Japanese children with non–high-density lipoprotein cholesterol measured between ages 9 and 11 years. Data were collected from 2015 to 2019, and analyses were conducted in 2024. A time-homogeneous continuous-time Markov model was used to estimate the probabilities of transitioning among non–high-density lipoprotein cholesterol classifications—acceptable (&lt;120 mg/dL), borderline high (120-144 mg/dL), and high (≥145 mg/dL)—and the average duration children remained in a given non–high-density lipoprotein cholesterol classification before transitioning.</div></div><div><h3>Results</h3><div>At the population level, all non–high-density lipoprotein cholesterol classifications identified at age 9 years were estimated to remain stable for more than 2 years. Children with acceptable non–high-density lipoprotein cholesterol had a mean duration of 10.6 years (95% CI=7.8, 14.5) before transitioning to another classification, with an estimated 0.90 probability of maintaining in the acceptable classification during the 9–11-year window.</div></div><div><h3>Conclusions</h3><div>Non–high-density lipoprotein cholesterol classifications identified at age 9 years remained stable for over 2 years, supporting the appropriateness of screening at any point within the 9–11-year window. These findings offer insights into optimal lipid-screening practices, thereby enhancing early cardiovascular disease prevention.</div></div>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":"70 5","pages":"Article 108243"},"PeriodicalIF":4.5,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying the Dementia Burden Attributable to Excess Weight in the U.S. 量化美国超重引起的痴呆负担。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-22 DOI: 10.1016/j.amepre.2025.108231
Jordan Weiss, Meghan I Podolsky, Rafeya V Raquib, Phillip Hwang, Andrew C Stokes

Introduction: Studies assessing the risk of dementia associated with excess weight have found mixed results owing to methodologic challenges. This study sought to quantify this relationship while avoiding the confounding that is attributable to reverse causality.

Methods: This cohort study used data from the Health and Retirement Study (1992-2018) analyzed in 2024-2025. The exposure was maximum BMI over 10 years of weight history before the start of follow-up. Participants were followed for 16 years for incident dementia, death, or censoring. Population attributable fractions for dementia were calculated using hazard ratios from multivariable Cox proportional hazards models and prevalence of overweight and obesity.

Results: The final sample comprised 3,734 individuals (57.1% female, mean age = 64.7 [SD = 4.4]) years, and 395 incident dementia cases). Compared with those with a maximum BMI in the normal weight range (18.5-24.9 kg/m2), the Class II/III obesity group (≥35 kg/m2) had almost double the hazard of dementia over follow-up (adjusted hazard ratio=1.89, 95% CI=1.31, 2.73), the Class I obesity group (30-34.9 kg/m2) had 42% increased hazard (95% CI=1.01, 2.00), and the overweight group (25-29.9 kg/m2) had 22% increased hazard (95% CI=0.89, 1.67). If all individuals with a maximum BMI in the overweight or obesity range had been in the normal weight group, 22.1% (95% CI=1.8, 38.2) of dementia cases could have potentially been averted.

Conclusions: The contribution of obesity to the burden of dementia is larger than current evidence suggests. Investigating this association without accounting for the complexity of the temporal relationship between obesity and dementia can result in erroneous conclusions.

导言:由于方法上的挑战,评估与超重相关的痴呆风险的研究发现了不同的结果。本研究试图量化这种关系,同时避免可归因于反向因果关系的混淆。方法:本队列研究使用2024-2025年健康与退休研究(1992-2018)的数据进行分析。暴露量是随访开始前10年体重史上的最大BMI值。研究人员对参与者进行了16年的痴呆、死亡或审查。使用多变量Cox比例风险模型的风险比(hr)和超重和肥胖患病率计算痴呆症的人群归因分数。结果:最终样本包括3734人(57.1%为女性,平均年龄64.7岁[SD 4.4])和395例痴呆病例。与最大BMI在正常体重范围(18.5-24.9 kg/m2)的患者相比,II/III级肥胖组(35+ kg/m2)的痴呆风险在随访期间几乎增加了一倍(调整[a]HR 1.89, CI 1.31, 2.73), I级肥胖组(30-34.9 kg/m2)的风险增加了42% (CI 1.01, 2.00),超重组(25-29.9 kg/m2)的风险增加了22% (CI 0.89, 1.67)。如果所有体重指数在超重或肥胖范围内的个体都属于正常体重组,那么22.1% (CI 1.8, 38.2)的痴呆病例可能会被避免。结论:肥胖对痴呆负担的贡献比目前的证据显示的要大。研究这种关联而不考虑肥胖和痴呆之间时间关系的复杂性可能会导致错误的结论。
{"title":"Quantifying the Dementia Burden Attributable to Excess Weight in the U.S.","authors":"Jordan Weiss, Meghan I Podolsky, Rafeya V Raquib, Phillip Hwang, Andrew C Stokes","doi":"10.1016/j.amepre.2025.108231","DOIUrl":"10.1016/j.amepre.2025.108231","url":null,"abstract":"<p><strong>Introduction: </strong>Studies assessing the risk of dementia associated with excess weight have found mixed results owing to methodologic challenges. This study sought to quantify this relationship while avoiding the confounding that is attributable to reverse causality.</p><p><strong>Methods: </strong>This cohort study used data from the Health and Retirement Study (1992-2018) analyzed in 2024-2025. The exposure was maximum BMI over 10 years of weight history before the start of follow-up. Participants were followed for 16 years for incident dementia, death, or censoring. Population attributable fractions for dementia were calculated using hazard ratios from multivariable Cox proportional hazards models and prevalence of overweight and obesity.</p><p><strong>Results: </strong>The final sample comprised 3,734 individuals (57.1% female, mean age = 64.7 [SD = 4.4]) years, and 395 incident dementia cases). Compared with those with a maximum BMI in the normal weight range (18.5-24.9 kg/m<sup>2</sup>), the Class II/III obesity group (≥35 kg/m<sup>2</sup>) had almost double the hazard of dementia over follow-up (adjusted hazard ratio=1.89, 95% CI=1.31, 2.73), the Class I obesity group (30-34.9 kg/m<sup>2</sup>) had 42% increased hazard (95% CI=1.01, 2.00), and the overweight group (25-29.9 kg/m<sup>2</sup>) had 22% increased hazard (95% CI=0.89, 1.67). If all individuals with a maximum BMI in the overweight or obesity range had been in the normal weight group, 22.1% (95% CI=1.8, 38.2) of dementia cases could have potentially been averted.</p><p><strong>Conclusions: </strong>The contribution of obesity to the burden of dementia is larger than current evidence suggests. Investigating this association without accounting for the complexity of the temporal relationship between obesity and dementia can result in erroneous conclusions.</p>","PeriodicalId":50805,"journal":{"name":"American Journal of Preventive Medicine","volume":" ","pages":"108231"},"PeriodicalIF":4.5,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Social Media to Increase Participation in Universal Free School Meal Programs: An RCT With Parents of Elementary-Aged Children. 利用社会媒体提高全民免费校餐计划的参与度:一项针对小学学龄儿童家长的随机对照试验。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-22 DOI: 10.1016/j.amepre.2025.108232
Anna H Grummon, Amanda B Zeitlin, Cristina J Y Lee, Christina A Hecht, Anisha I Patel, Kenneth Hecht, Andrea Pedroza-Tobias

Introduction: As of 2025, 9 states have adopted Universal Free School Meal programs. The success of these programs depends in part on high participation. This study tested whether a social media campaign promoting school meal participation increases school lunch and breakfast participation in states with Universal Free School Meal programs.

Study design: This was an RCT.

Setting/participants: A total of 832 parents of elementary-aged children living in states with Universal Free School Meal programs were included.

Intervention: Parents were randomized to a school meal promotion campaign or a control campaign about reading. Campaigns were delivered through private Facebook groups for 6 weeks between October and December 2024.

Main outcome measures: The coprimary outcomes were children's school lunch and school breakfast participation as reported by parents in baseline and follow-up surveys. Secondary outcomes included engagement with the campaigns (e.g., noticing, reading, and talking about campaign messages) and perceived barriers to participation in school meals. Data were collected in September-December 2024 and analyzed in 2025.

Results: The school meal promotion campaign elicited more noticing of the campaign messages (difference versus control, 37 percentage points); reading the campaign messages (difference=0.16 on a 1-5 scale); and talking with others about the campaign messages, school meals, and the benefits of school meals (differences=0.14-0.21 on 1-5 scales) (all ps<0.05). The campaign did not increase participation either in school lunch (difference-in-differences=0.08 meals/week, 95% CI= -0.08, 0.25, p=0.30) or breakfast (difference-in-differences=0.02 meals/week, 95% CI= -0.16, 0.20, p=0.81). Parents reported several barriers to their child's participating in school lunch and breakfast, including that the child does not like the meals (38%-63% of parents reported), the meals appear to be low quality (17%-27%), and there is not enough time to eat (25%-30%).

Conclusions: Delivering school meal promotion campaigns to parents through Facebook is feasible and acceptable but may not be sufficient to increase children's school meal participation.

Trial registration: This study is registered at ClinicalTrials.gov (NCT#06419218).

导读:截至2025年,美国有9个州实施了全民免费校餐计划。这些项目的成功部分取决于高参与度。这项研究测试了在实施普遍免费学校膳食计划的州,促进学校膳食参与的社交媒体活动是否会增加学校午餐和早餐的参与。研究设计:随机对照试验。设置/参与:832名小学适龄儿童的父母,他们生活在实行全民免费校餐计划的州。干预:家长们被随机分配到学校膳食推广活动或关于阅读的对照活动中。2024年10月至12月期间,竞选活动通过私人Facebook群组进行,为期6周。主要结果测量:共同的主要结果是家长在基线和随访调查中报告的儿童学校午餐和学校早餐的参与情况。次要结果包括参与活动(例如,注意、阅读和谈论活动信息)和参与学校膳食的感知障碍。数据于2024年9月至12月收集,并于2025年进行分析。结果:学校供餐促销活动引起了更多的注意活动信息(差异与对照组,37个百分点),阅读活动信息(差异=0.16,1-5量表),并与他人谈论活动信息,学校供餐和学校供餐的好处(差异=0.14至0.21,1-5量表)(所有ps7)。通过Facebook向家长提供校餐促销活动是可行和可接受的,但可能不足以增加儿童的校餐参与。试验注册:ClinicalTrials.gov (nct# 06419218)。
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引用次数: 0
Neural Predictors of Vaping: Covert Emotional Engagement Versus Reactance to Overt Emotional Appeals in Vaping Prevention Message Processing. 电子烟的神经预测:在电子烟预防信息处理中,隐蔽情感投入与对公开情感诉求的抗拒。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-19 DOI: 10.1016/j.amepre.2025.108194
Jiaying Liu, Yidi Wang, Jessica L Fabbricatore, Emily Norton, Colleen E Markey, Joshua T McMains, Allison Worsdale, Tianlai Ye, Zhenhao Shi, Lawrence H Sweet

Introduction: Vaping products are the most widely used tobacco products among young adults in the U.S., driven partly by added flavors that are palatable and misperceived as safe. Vaping prevention public service announcements often use cognitive, emotional, and social appeals, yet little is known about the neurobehavioral mechanisms driving their effectiveness. This study employed functional magnetic resonance imaging to determine whether neural responses to vaping prevention public service announcements in the salience, emotional, cognitive control, and default mode networks predict subsequent vaping and whether these effects vary by message type.

Methods: Forty-six young adult nonsmokers who vaped ≥15 days during the past month viewed vaping prevention public service announcements during functional magnetic resonance imaging. Public service announcements were adapted from existing campaigns with cognitive, emotional, and social appeals. Subsequent vaping behavior was tracked weekly for 1 month. Data were collected between 2019 and 2022, with formal analyses conducted in 2024.

Results: Greater reactivity in the emotional network during public service announcement exposure predicted reduced vaping 1 month later, especially when viewing cognitive and social public service announcement. In contrast, heightened cognitive control network reactivity was linked to increased vaping, driven primarily by responses to emotional public service announcements.

Conclusions: Emotional network responses to cognitive and social public service announcements and cognitive control responses to emotional public service announcements may serve as useful and possibly differential neuromarkers of future vaping behavior. Specifically, public service announcements that elicit reflective emotional processing may be more effective than those relying on overt emotional intensity. These findings suggest the utility of functional magnetic resonance imaging in informing optimization of health message design in the evolving nicotine product landscape.

电子烟产品是美国年轻人中使用最广泛的烟草产品,部分原因是添加了美味的香料,被误认为是安全的。预防电子烟的公益广告经常使用认知、情感和社会吸引力,但人们对推动其有效性的神经行为机制知之甚少。本研究采用功能性磁共振成像来确定在显著性、情绪、认知控制和默认模式网络中,预防电子烟公共服务广告的神经反应是否能预测随后的电子烟行为,以及这些影响是否因信息类型而异。方法:46名在过去一个月内吸电子烟≥15天的年轻非吸烟者在功能磁共振成像期间观看了电子烟预防公共服务广告。公益广告改编自已有的具有认知、情感和社会吸引力的活动。随后的电子烟行为每周被跟踪一个月。数据收集于2019年至2022年,并于2024年进行正式分析。结果:在观看认知和社会公益广告时,情绪网络的反应性增加预示着1个月后吸烟量的减少,尤其是在观看认知和社会公益广告时。相比之下,认知控制网络反应的增强与电子烟的增加有关,这主要是由对情绪化的公共服务广告的反应所驱动的。结论:对认知和社会公益广告的情绪网络反应和对情绪公益广告的认知控制反应可能是未来电子烟行为的有用和可能的差异神经标志物。具体来说,引发反思性情绪处理的公益广告可能比那些依赖于公开情绪强度的广告更有效。这些发现表明功能性磁共振成像在不断发展的尼古丁产品景观中为健康信息设计的优化提供了信息。
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引用次数: 0
Chronic Conditions as Risk Factors for COVID-19-Associated Hospitalization Among Adults, 2020-2023. 慢性疾病是2020-2023年成人covid -19相关住院的危险因素。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-19 DOI: 10.1016/j.amepre.2025.108227
Sarah Hamid, Gordana Derado, Huong Pham, Rebecca C Woodruff, Michael Melgar, Jeremy L Roland, Breanna Kawasaki, James Meek, Lucy S Witt, Maya L Monroe, Libby Reeg, Erica Martin, Jennifer E Akpo, Grant Barney, Christina B Felsen, Nancy Moran, Melissa Sutton, H Keipp Talbot, Ashley Swain, Fiona P Havers, Christopher A Taylor

Introduction: Chronic conditions associated with COVID-19 hospitalization were identified early in the pandemic when underlying population immunity was low. Updated information on risk factors for COVID-19 hospitalization is needed.

Methods: Surveillance and cross-sectional survey data were combined to compare COVID-19 hospitalization rates in adults aged ≥18 years with and without nine chronic conditions in 98 counties across 13 states. Hospitalization counts were obtained from the COVID-19-associated Hospitalization Surveillance Network. The adult population with and without chronic conditions was estimated from U.S. Census data and the Behavioral Risk Factor Surveillance System. Adjusted rate ratios (aRRs) were estimated using Poisson regression with Monte Carlo simulation, adjusting for age group, sex, and race and ethnicity.

Results: From October 2022 through September 2023 (2022-2023), compared to adults without a given condition, COVID-19 hospitalization rates were greater among adults with chronic kidney disease (aRR [95% uncertainty interval]: 4.5 [3.4-5.9]), diabetes (2.2 [1.7-2.8]), stroke (2.1 [1.5-2.9]), severe obesity (2.0 [1.5-2.8]), coronary artery disease (2.0 [1.5-2.5]), COPD (1.9 [1.5-2.5]), smoking (1.5 [1.2-2.0]) and asthma (1.5 [1.1-2.0]). Non-severe obesity was not associated with increased risk. Hospitalization rates were 18.0 times higher among adults aged ≥75 years vs 18-49 years. Compared to earlier seasons (2020-2022), more hospitalized adults in 2022-2023 had ≥3 chronic conditions and were aged ≥75 years.

Conclusions: Eight of nine chronic conditions assessed were associated with increased risk of COVID-19 hospitalization; risk varied by condition and age. Older age was the strongest risk factor. Findings can guide prevention and treatment by identifying populations at greatest risk of COVID-19 hospitalization.

导论:与COVID-19住院相关的慢性疾病在大流行早期被发现,当时潜在的人群免疫力较低。需要关于COVID-19住院风险因素的最新信息。方法:将监测数据和横断面调查数据相结合,比较13个州98个县有和没有9种慢性病的≥18岁成人COVID-19住院率。住院次数来自与covid -19相关的住院监测网络。根据美国人口普查数据和行为风险因素监测系统估计有和没有慢性疾病的成年人口。使用泊松回归和蒙特卡罗模拟来估计调整后的发病率比(aRRs),调整了年龄组、性别、种族和民族。结果:从2022年10月至2023年9月(2022-2023),与没有特定疾病的成年人相比,慢性肾脏疾病(aRR[95%不确定区间]:4.5[3.4-5.9])、糖尿病(2.2[1.7-2.8])、中风(2.1[1.5-2.9])、严重肥胖(2.0[1.5-2.8])、冠状动脉疾病(2.0[1.5-2.5])、COPD(1.9[1.5-2.5])、吸烟(1.5[1.2-2.0])和哮喘(1.5[1.1-2.0])的成人COVID-19住院率更高。非重度肥胖与风险增加无关。≥75岁成人的住院率是18-49岁成人的18.0倍。与早期季节(2020-2022年)相比,2022-2023年住院的成年人中有更多患有≥3种慢性疾病且年龄≥75岁。结论:评估的9种慢性疾病中有8种与COVID-19住院风险增加相关;风险因病情和年龄而异。年龄较大是最大的危险因素。研究结果可以通过确定COVID-19住院风险最高的人群来指导预防和治疗。
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引用次数: 0
Severe Maternal Morbidity at the Intersection of Race and Disability: Evidence of Compounded Disparities in the U.S. Maternal Healthcare System 严重的产妇发病率在种族和残疾的交集:证据复合差距在美国产妇保健系统。
IF 4.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-12-18 DOI: 10.1016/j.amepre.2025.108229
Ilhom Akobirshoev PhD, MA, MSW , Willi Horner-Johnson PhD , Anne Valentine PhD , Ruby Siegel BA , Monika Mitra PhD

Introduction

The aim of this study was to examine severe maternal morbidity at the intersection of race and physical disability status using nationally representative data.

Methods

This study conducted a pooled cross-sectional analysis of delivery hospitalizations in 2025 using 2004–2022 Healthcare Cost and Utilization Project Nationwide Inpatient Sample data. Delivery hospitalizations and physical disabilities were identified using validated International Classification of Diseases, Ninth/ICD-10 Revisions–based algorithms. The primary outcome was severe maternal morbidity excluding blood transfusion–only cases. Secondary outcomes included severe maternal morbidity severity measured by the number of severe maternal morbidity indicators (≥2 or ≥3) and specific severe maternal morbidity categories. Risk ratios were calculated using modified Poisson regression and evaluated additive interaction using the Relative Excess Risk due to Interaction and Attributable Proportion.

Results

Among 8,584,800 delivery hospitalizations, 88,389 (1.0%) were to women with physical disabilities. Black disabled women with 528 per 10,000 deliveries (528.0; 95% CI=492.8, 565.5) had the highest rates of severe maternal morbidity, followed by White women with physical disabilities (213.9; 95% CI=203.6, 224.7) and Black women without physical disabilities (107.7; 95% CI=105.3, 110.1). White women without physical disabilities with 61 per 10,000 deliveries (60.7; 95% CI=59.4, 62.1) had the lowest rate of severe maternal morbidity. After adjustment, Black women with physical disabilities had 6.92 times the risk of severe maternal morbidity (95% CI=6.45, 7.44) compared with White women without disabilities. The adjusted Relative Excess Risk due to Interaction for severe maternal morbidity was 2.07 (95% CI=1.67, 2.47), and the Attributable Proportion due to interaction was 0.38 (95% CI=0.33, 0.43), suggesting that 38% of excess risk among Black women with physical disabilities was attributable to the interaction between race and physical disability.

Conclusions

Black women with physical disabilities experience compounded risks of severe maternal morbidity that exceed the sum of risks associated with race or physical disability alone. These findings underscore the need for intersectional approach to develop effective interventions to improve maternal care quality and outcomes in this high-risk population.
简介:检查严重产妇发病率(SMM)在种族和身体残疾状况的交叉点使用全国代表性的数据。方法:本研究利用2004-2022年医疗成本和利用项目全国住院患者样本(HCUP-NIS)数据,对2025年分娩住院进行汇总横断面分析。使用经过验证的基于icd -9/10的算法确定分娩住院和身体残疾。主要终点是SMM,不包括仅输血的病例。次要结局包括以SMM指标数量衡量的SMM严重程度(≥2或≥3);以及具体的SMM类别。使用修正泊松回归计算风险比,并使用相互作用的相对超额风险(rei)和归因比例(AP)评估加性相互作用。结果:在8,584,800例分娩住院患者中,88,389例(1.0%)为身体残疾妇女。黑人残疾妇女的SMM发生率最高,为528 / 10,000 (528.0;95%CI:492.8-565.5),其次是身体残疾的白人妇女(213.9;203.6-224.7)和没有身体残疾的黑人妇女(107.7;95%CI:105.3-110.1)。没有身体残疾的白人妇女的SMM率最低,每10,000个分娩中有61个(60.7;95%CI:59.4-62.1)。调整后,有身体残疾的黑人女性患SMM的风险是没有残疾的白人女性的6.92倍(95%CI:6.45-7.44)。SMM的调整后的rei为2.07 (95%CI:1.67-2.47),相互作用的AP为0.38 (95%CI:0.33-0.43),表明黑人身体残疾妇女中38%的额外风险可归因于种族和身体残疾之间的相互作用。结论:有身体残疾的黑人女性经历了SMM的复合风险,超过了与种族或身体残疾单独相关的风险总和。这些发现强调需要采取交叉方法来制定有效的干预措施,以改善这一高危人群的孕产妇护理质量和结果。
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引用次数: 0
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American Journal of Preventive Medicine
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