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Biological Benchmarks for Adult Bone Mass Proportions in Young Females: A Prospective Longitudinal Analysis 年轻女性成年骨量比例的生物学基准:一项前瞻性纵向分析
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-13 DOI: 10.1002/ajhb.70118
Jodi N. Dowthwaite, Stephanie A. Kliethermes, Tamara A. Scerpella

Objectives

In growing humans, densitometric scans of whole-body bone mass “less head” are recommended to circumvent the excessive contribution of youths' proportionally larger heads but potentially inflate inter-scan variation and least significant change due to measurement error. We aimed to determine biological benchmarks for achievement of adult head-body proportions in a sample of US females.

Methods

Annual whole-body dual energy x-ray absorptiometry (DXA) scans tracked growth, maturation, and bone mass accrual in a prospective longitudinal cohort of girls for up to 19 years (baseline age 7–15 years). We used cubic smoothing spline mixed effects models to generate chronological and gynecological age-based curves for head versus whole-body bone mass proportions (ratios). Females with ≥ 3 annual scans were included (n = 148, age 7–30 years).

Results

Models yielded trajectories extending beyond observed age at peak bone mass for our sample. From age 18 years, “adult” mean of means for head vs. whole-body bone mass proportions was 0.204 (n = 66: 95% confidence interval = 0.198–0.210). Individual proportions stabilized to “adult” mean levels circum-menarche (n = 124: mean = 0.198; 95% confidence interval = 0.194–0.202). The minimum age for 95% confidence intervals overlapping with adult values was 12 years, circum-peak height velocity (n = 120: mean = 0.211; 95% confidence interval = 0.207–0.216).

Conclusion

In US girls with diverse activity exposures, head vs. whole-body bone mass proportions are “adult” from menarche onward; an “adult” age threshold of 12 years, or age at peak height velocity, may be used in the absence of extreme maturational delay to evaluate whole-body bone mass including the head.

在成长中的人类中,推荐使用“少头”的全身骨量密度扫描,以避免青少年比例较大的头部对骨量的过度贡献,但可能会增加扫描间的变化,并且由于测量误差导致的变化不显著。我们的目的是确定在美国女性样本中实现成人头身比例的生物学基准。方法:在长达19年(基线年龄7-15岁)的前瞻性纵向队列中,每年进行一次全身双能x线吸收仪(DXA)扫描,跟踪女孩的生长、成熟和骨量积累。我们使用三次平滑样条混合效应模型来生成头部与全身骨量比例(比率)的时间和妇科年龄曲线。纳入每年扫描3次以上的女性(n = 148,年龄7-30岁)。结果在我们的样本中,模型产生的轨迹超出了观察到的骨量峰值年龄。从18岁开始,头部与全身骨量比例的“成人”平均值为0.204 (n = 66: 95%可信区间= 0.198-0.210)。个体比例稳定在月经初潮前后的“成人”平均水平(n = 124:平均值= 0.198;95%置信区间= 0.194-0.202)。与成人值重叠95%置信区间的最小年龄为12岁,环峰高度速度(n = 120,平均值= 0.211;95%置信区间= 0.207-0.216)。结论:在不同活动暴露的美国女孩中,从月经初潮开始,头部与全身骨量比例是“成人”的;“成人”年龄阈值为12岁,或峰值高度速度年龄,在没有极端成熟延迟的情况下可用于评估包括头部在内的全身骨量。
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引用次数: 0
Species-Specific Helminth Effects, Ecoimmunology, and Indigenous Health: Commentary on Cepon-Robins et al. (2025) 物种特异性蠕虫效应、生态免疫学和土著健康:对Cepon-Robins等人的评论(2025)
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-13 DOI: 10.1002/ajhb.70117
Nathkapach Kaewpitoon Rattanapitoon, Kornmaneethana Punnasirimangmee, Pattharasedthi Pholyiam, Schawanya Kaewpitoon Rattanapitoon
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引用次数: 0
Association Between Motor Competence, Executive Functions, and Self-Regulation: A Complex Systems Approach 运动能力、执行功能和自我调节之间的联系:一个复杂系统的方法
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-12 DOI: 10.1002/ajhb.70110
Morgana Alves Correia da Silva, Clarice Maria de Lucena Martins, Michelly Alencar Alencar, Paulo Renato Alves Firmino, Paulo Felipe Ribeiro Bandeira
<div> <section> <h3> Background</h3> <p>There are several associated factors that have an impact on a child's development, including the cognitive and motor domains. Motor competence is intrinsically linked to executive functioning, even though the causal links between the development of motor skills and the development of cognitive skills are not always obvious. Even in early childhood, with advances in cognitive processes in the child's development, processes emerge that make the child capable of regulating their own behavior.</p> </section> <section> <h3> Objectives</h3> <p>These variables are important for child development; however, there are no previous studies that examine the associations of motor competence, executive functions, and self-regulation together. There is also no study that takes a holistic view to better understand the interrelationships of these variables. This study aimed to investigate the association between motor competence, executive functions, and self-regulation in childhood and identify the variables with the highest network influence values.</p> </section> <section> <h3> Methods</h3> <p>The research adopted a cross-sectional design; it is a descriptive and associative study. Two hundred and eighty-three children aged 3–6 years of both sexes, from two of the most populous cities in the interior of northeastern Brazil participated. The instruments used were the TGMD-3 for motor competence, the Early Years Toolbox battery for executive functions, and HTKS-R for self-regulation. The data was analyzed using network analysis.</p> </section> <section> <h3> Results</h3> <p>It was observed that motor competence and executive functions were positively related, and self-regulation had an indirect association with motor competence. These findings corroborate previous studies on the relationship between motor competence and executive functions and highlight the importance of self-regulation in this association. The network showed clusters between motor competence skills, executive functions, and self-regulation, which are part of the same construct. The skills of running, receiving, kicking, and inhibitory control had the highest centrality rates, highlighting their importance for the interconnection of variables. The highest values of expected influence were from running, inhibitory control, and kicking, modifications of which can result in significant changes in the overall behavior of the network.</p> </section> <section> <h3> Conclusions</h3> <p>These findings reinforce the integrated nature of motor, cognitive, and self-regulat
有几个相关的因素影响儿童的发展,包括认知和运动领域。运动能力与执行功能有着内在的联系,尽管运动技能的发展与认知技能的发展之间的因果关系并不总是很明显。即使在儿童早期,随着儿童发展过程中认知过程的进步,也出现了使儿童能够调节自己行为的过程。这些变量对儿童发展很重要;然而,以前没有研究将运动能力、执行功能和自我调节联系在一起。也没有研究采取整体的观点来更好地理解这些变量之间的相互关系。本研究旨在探讨儿童运动能力、执行功能和自我调节之间的关系,并找出具有最高网络影响值的变量。方法采用横断面设计;这是一个描述性和联想性的研究。来自巴西东北部两个人口最多的内陆城市的283名年龄在3-6岁的男女儿童参加了这项研究。采用TGMD-3测试运动能力,早期工具箱测试执行功能,HTKS-R测试自我调节。采用网络分析法对数据进行分析。结果运动能力与执行功能呈正相关,自我调节与运动能力有间接关联。这些发现证实了先前关于运动能力和执行功能之间关系的研究,并强调了自我调节在这一关联中的重要性。该网络显示出运动能力技能、执行功能和自我调节之间的集群,它们是同一结构的一部分。跑步、接球、踢腿和抑制控制的技能具有最高的中心性率,突出了它们对变量互连的重要性。预期影响的最高值来自奔跑、抑制控制和踢脚,这些变化可能导致网络整体行为的显著变化。这些发现强化了儿童时期运动、认知和自我调节过程的整合性,表明特定技能(如跑步、抑制控制)在发展网络中起着核心作用。
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引用次数: 0
The Fertility Effects of the C677T Mutation in the Methylenetetrahydrofolate Reductase Gene: A Cross-Site Systematic Review and Meta-Analysis 亚甲基四氢叶酸还原酶基因C677T突变对育性的影响:一项跨位点系统评价和荟萃分析
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-11 DOI: 10.1002/ajhb.70119
Caroline A. MacLean, Miguel Dimanlig, David Godfrey, Lorena Madrigal

Introduction

In this research, we seek to understand the evolutionary forces which have resulted in the distribution of the MTHFR C677T single nucleotide polymorphism, which is associated with fertility-related, cardiovascular, cancerous, and neurological morbidities. Due to the negative effects of the gene, it is likely frequent due to genetic drift or natural selection.

Methods

Using secondary data gathered by systematic review, we test proposals stating that under conditions of ample folate, individuals who are heterozygous (CT) and homozygous (TT) for the MTHFR C677T polymorphism would suffer from fewer or no deleterious pregnancy or birth outcomes. Using descriptive and bivariate statistics, we determined if significant differences exist between pregnancy or birth outcomes based on genotype. We then modeled the effects of genotype, folate, cobalamin, and homocysteine (and their interactions) on the frequency of the pregnancy outcomes.

Results

Even with ample and high serum folate, CT and TT women sampled had worse pregnancy outcomes. Folate (sometimes interacting with insolation) mediates pregnancy outcomes in a genotype-dependent fashion. For this reason, we caution against the use of a “one size fits all” approach to clinical treatment for CT and TT individuals.

Conclusions

We conclude that natural selection is the primary force of evolution acting on this mutation despite its numerous negative effects. We reject the hypothesis that in conditions of ample folate supply, CT or TT pregnant people might have a fitness advantage. Genotype was a strong predictor of birth outcomes, indicating that for this polymorphism, there is a strong folate-genotypic and genotype-insolation interaction.

在这项研究中,我们试图了解导致MTHFR C677T单核苷酸多态性分布的进化力量,该多态性与生育相关、心血管、癌症和神经系统疾病有关。由于基因的负面影响,它很可能是由于遗传漂变或自然选择而频繁发生的。方法利用系统评价收集的次要数据,我们验证了在叶酸充足的条件下,MTHFR C677T多态性的杂合(CT)和纯合(TT)个体会遭受更少或没有有害的妊娠或分娩结局。使用描述性和双变量统计,我们确定了基于基因型的妊娠或分娩结局之间是否存在显著差异。然后,我们模拟了基因型、叶酸、钴胺素和同型半胱氨酸(及其相互作用)对妊娠结局频率的影响。结果即使血清叶酸充足且较高,CT和TT抽样的妇女妊娠结局较差。叶酸(有时与日照相互作用)以基因型依赖的方式介导妊娠结局。出于这个原因,我们警告不要使用“一刀切”的方法对CT和TT个体进行临床治疗。我们得出结论,自然选择是作用于这种突变的进化的主要力量,尽管它有许多负面影响。我们拒绝假设,在充足的叶酸供应条件下,CT或TT孕妇可能有健康优势。基因型是出生结果的一个强有力的预测因子,表明这种多态性存在强烈的叶酸-基因型和基因型-日照相互作用。
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引用次数: 0
Is There Any Possible Relationship Between Antenatal Hydronephrosis and Prenatal Androgen Exposure? An Analysis Using the 2D:4D Digit Ratio 产前肾积水与产前雄激素暴露有关系吗?使用2D:4D数字比的分析
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-05 DOI: 10.1002/ajhb.70114
Sinan Kılıç, Çiğdem Kılıç

Objectives

The ratio of the index finger to the ring finger length (2D:4D) differs between sexes; it is typically higher in females than in males. This difference is thought to be related to intrauterine androgen exposure. Antenatal hydronephrosis is the most frequently detected anomaly during prenatal ultrasonographic evaluation of fetal development. This study aims to investigate the relationship between the 2D:4D ratio in newborns and the presence of congenital hydronephrosis.

Methods

Between July 2023 and April 2024, the lengths of the second and fourth digits and medical birth records of newborns were documented. Infants who were followed antenatally for hydronephrosis and exhibited persistent findings on postnatal renal ultrasonography were included in the study group. The control group consisted of newborns without any antenatal or postnatal renal abnormalities.

Results

A total of 82 newborns were included in the analysis. Among them, 50 had no antenatal or postnatal renal anomalies and comprised the control group. In 32 newborns, both antenatal and postnatal hydronephrosis were diagnosed. The 2D:4D was significantly higher in the hydronephrosis group compared to the control group (p < 0.001). No significant differences were found between right and left hand 2D:4D measurements within either group (p > 0.05).

Conclusion

The observation of significantly higher 2D:4D ratios in newborns with antenatal hydronephrosis may suggest a possible association with decreased prenatal androgen exposure. While the 2D:4D ratio is generally expected to be higher in females and lower in males, the finding of higher ratios in newborns with hydronephrosis may indicate a reduced androgen effect during fetal development in these cases. Although this finding is consistent with the fact that hydronephrosis is more frequently observed in male fetuses, it should be interpreted with caution and supported by further studies.

目的两性食指与无名指长度之比(2D:4D)存在差异;通常情况下,女性的这一比例高于男性。这种差异被认为与宫内雄激素暴露有关。产前肾积水是胎儿发育超声检查中最常见的异常。本研究旨在探讨新生儿2D:4D比值与先天性肾积水的关系。方法对2023年7月~ 2024年4月出生的新生儿进行二、四指长度和出生病历的记录。在产前进行肾积水随访并在产后肾超声检查中表现出持续表现的婴儿被纳入研究组。对照组为未出现任何产前或产后肾脏异常的新生儿。结果共纳入82例新生儿。其中50例无产前或产后肾异常,作为对照组。在32例新生儿中,诊断为产前和产后肾积水。肾积水组的2D:4D明显高于对照组(p < 0.001)。两组的右手和左手2D:4D测量结果均无显著差异(p > 0.05)。结论产前肾积水新生儿2D:4D比值明显增高,可能与产前雄激素暴露减少有关。一般认为,2D:4D比值在女性中较高,而在男性中较低,但在新生儿肾积水中发现较高的比值可能表明,在这些情况下,胎儿发育过程中雄激素作用降低。尽管这一发现与在男性胎儿中更常观察到肾积水的事实相一致,但应谨慎解释,并得到进一步研究的支持。
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引用次数: 0
The Ecology and Human Biology of Pastoralists: Building on the Contributions of Michael A. Little 牧民的生态学和人类生物学:基于Michael A. Little的贡献
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-04 DOI: 10.1002/ajhb.70115
William R. Leonard

Human biologists have long studied the ecology, health, and adaptive patterns of pastoralist populations around the world. Over the last 20 years, research among pastoralists has increasingly focused on how ongoing climatic and socioeconomic changes are influencing these populations and threatening this lifeway. Additionally, with the development and broader use of “field friendly” methods for measuring energy expenditure, metabolism, and diverse biomarkers of physiological health, we are now able to gain a much more detailed and dynamic picture of the adaptive strategies of pastoralists. This Virtual Special Issue of the American Journal of Human Biology, “Human Biology of Pastoralists Populations” (Edited by Benjamin Campbell), showcases important advancements in this research domain and highlights the foundational contributions of Michael A. Little to our understanding of the biology and health of pastoralist societies.

人类生物学家长期以来一直在研究世界各地牧民的生态、健康和适应模式。在过去的20年里,对牧民的研究越来越关注持续的气候和社会经济变化如何影响这些人口并威胁到他们的生活方式。此外,随着“野外友好”方法的发展和广泛使用,用于测量能量消耗、新陈代谢和生理健康的各种生物标志物,我们现在能够获得更详细和动态的牧民适应策略图片。《美国人类生物学杂志》的虚拟特刊“牧民群体的人类生物学”(本杰明·坎贝尔编辑)展示了这一研究领域的重要进展,并强调了迈克尔·a·利特尔对我们理解牧民社会的生物学和健康的基础贡献。
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引用次数: 0
Systematic Review and Meta-Analysis of the Prevalence of Physical Activity in South American Children 南美儿童体育活动流行率的系统回顾和荟萃分析
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-01 DOI: 10.1002/ajhb.70112
Luciana Leite Silva Barboza, Raphael Henrique de Oliveira Araujo, Maria Luiza Felix Pessoa, Danilo Rodrigues Pereira da Silva, Clarice Maria de Lucena Martins, the South American Physical Activity and Sedentary Behavior Network (SAPASEN) Collaborators

Objectives

This study aimed to systematically review and apply meta-analytic procedures to investigate the prevalence and time spent in different physical activity (PA) intensities among South American children across the childhood spectrum, according to sex and protocol used.

Methods

We searched PubMed, Web of Science, Scopus, Latin American and Caribbean Health Sciences Literature (LILACS), and Scientific Electronic Library Online (SCiELO); only studies with children between 0 and 11 years were included. Random-effects meta-analysis models were used to calculate the pooled estimates with their respective 95% confidence intervals (CI). All analyses were conducted using Stata 18.0.

Results

The literature search yielded 12 217 articles, with 28 studies remaining relevant for this review. The main exclusion criteria for the manuscripts were lack of prevalence data and doubled data. Pooled estimates revealed that children spent 61.4 (95% CI, 54.4–68.5) min/day of moderate-vigorous PA (MVPA), with differences in the time spent between girls (mean: 49.8 [95% CI, 38.8–60.8]) and boys (mean: 63.4 [95% CI, 55.7–71.1]). We noticed a great variability in PA prevalence, which ranged from 1.7% to approximately 80%, and was consistently lower among girls. Studies using device-based measures tend to report lower levels of PA than those relying on self-reported data.

Conclusions

On average, South American children spend 61.4 min/day on MVPA, with high variability of both device-measured and self-reported PA. Regardless of the method used to measure PA, sex inequalities favorable to boys were noted.

本研究旨在系统回顾并应用荟萃分析程序,根据性别和使用的协议,调查南美儿童在整个儿童期中不同体育活动强度(PA)的患病率和花费的时间。方法检索PubMed、Web of Science、Scopus、Latin American and Caribbean Health Sciences Literature (LILACS)、Science Electronic Library Online (SCiELO);仅包括0至11岁儿童的研究。使用随机效应荟萃分析模型计算汇总估计值及其各自的95%置信区间(CI)。所有分析均使用Stata 18.0进行。结果文献检索得到12217篇文章,其中28篇与本综述相关。论文的主要排除标准是缺乏患病率数据和双重数据。汇总估计显示,儿童每天花61.4 (95% CI, 54.4-68.5)分钟进行中等强度PA (MVPA),女孩(平均值:49.8 [95% CI, 38.8-60.8])和男孩(平均值:63.4 [95% CI, 55.7-71.1])之间的时间存在差异。我们注意到PA患病率的差异很大,从1.7%到大约80%不等,女孩的患病率一直较低。使用基于设备的测量方法的研究报告的PA水平往往低于那些依赖于自我报告数据的研究。南美儿童平均每天在MVPA上花费61.4分钟,设备测量和自我报告的PA都具有很高的可变性。无论使用何种方法来测量PA,都注意到有利于男孩的性别不平等。
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引用次数: 0
The Effects of Meteorological Conditions on the Circadian Rhythm of Births. 气象条件对出生昼夜节律的影响。
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-08-01 DOI: 10.1002/ajhb.70120
Alessio Fornasin, Laura Rizzi, Giovanni Fonseca

Objective: The aim of this study is to evaluate the influences exerted by temperature on the circadian rhythm of births.

Methods: In the past births occurred mainly between midnight and dawn, while today births tend to be less frequent during the night hours. Today, almost all births are hospitalized and, therefore, they may adapt to the organizational requirements of the health care structures and staff. This piece of research regards births in Udine, a city in north-eastern Italy, recorded at the beginning of the 19th century. The data on births come from the French civil register. Weather data come from very detailed daily collection with three measurements per day. From the statistical point of view, we apply methods developed for circular data. In order to highlight relationships between time of birth and explanatory variables, we estimate MANOVA (multivariate analysis of variance) models and perform a statistical test for comparison between groups.

Results: The test against the homogeneity of the hour-of-birth distributions across the 4 seasons is significant (p < 0.01). One-to-one comparison of the distributions is performed via Watson's two-sample test on data for each couple of seasons: the Summer-Autumn comparison is the only non-significant test of homogeneity. Moreover, we consider daily temperatures in the bivariate model in several different ways and transformations. The daily temperature effect is more significant if considered as the difference between the evening temperature of the day before the birth and the mean daily temperature of the same day, over the nine-year period 1807-1815. Finally, based on this division of the births, Watson's two-sample homogeneity test for the distribution of the hour of birth is significant (p < 0.05).

Conclusions: We found that the circadian rhythm of births is influenced by temperature, with an anticipation of the time of birth on warmer days. To our knowledge, our results are the first evidence of the effects of daily temperature on the time of birth.

目的:探讨温度对新生儿昼夜节律的影响。方法:过去的分娩主要发生在午夜至黎明之间,而今天在夜间分娩的次数较少。今天,几乎所有的分娩都住院,因此,它们可以适应保健机构和工作人员的组织要求。这项研究涉及19世纪初意大利东北部城市乌迪内的出生记录。出生数据来自法国的民事登记。天气数据来自非常详细的日常收集,每天有三次测量。从统计的角度来看,我们应用为循环数据开发的方法。为了突出出生时间和解释变量之间的关系,我们估计了MANOVA(多变量方差分析)模型,并对组间比较进行了统计检验。结论:我们发现,出生的昼夜节律受到温度的影响,在温暖的日子出生的时间是预期的。据我们所知,我们的结果是每日温度对出生时间影响的第一个证据。
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引用次数: 0
Correction to “Unlocking Adolescence: A Novel Approach to Approximate the Sociocultural Implications of Puberty in Medieval Spain” 对“解开青春期:一种接近中世纪西班牙青春期社会文化含义的新方法”的更正
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-07-29 DOI: 10.1002/ajhb.70113

Doe D. M., N. Candelas González, J. A. Gutiérrez González, O. Cambra-Moo, A. González Martín. 2025. “Unlocking Adolescence: A Novel Approach to Approximate the Sociocultural Implications of Puberty in Medieval Spain.” American Journal of Human Biology 37, no. 5: e70054. https://doi.org/10.1002/ajhb.70054.

In the second paragraph of the Discussion section (page 9), the first sentence which reads “Skeletons with age-at-death estimations of 810 years were determined…” is incorrect. It should read “Skeletons with age-at-death estimations of 8, 9 and 10 years were determined…”

We apologize for this error.

Doe D. M., N. Candelas González, J. A. gutisamurez González, O. Cambra-Moo, A. González Martín。2025. “解开青春期:一种接近中世纪西班牙青春期社会文化含义的新方法”。《美国人类生物学杂志》第37期。5: e70054。https://doi.org/10.1002/ajhb.70054.In讨论部分(第9页)第二段,第一句“估计死亡年龄为810岁的骷髅被确定……”是不正确的。它应该是“骷髅的死亡年龄估计为8岁、9岁和10岁……”我们为这个错误道歉。
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引用次数: 0
Celebrating Over 10 Years of Human Milk Research in the Human Biology Association 人类生物学协会庆祝母乳研究超过10年
IF 1.7 4区 医学 Q1 ANTHROPOLOGY Pub Date : 2025-07-29 DOI: 10.1002/ajhb.70111
Elizabeth M. Miller, Masako Fujita, Katie Hinde, Melanie A. Martin, Katherine Wander, Elizabeth A. Quinn

Since we published “Field and Laboratory Methods in Human Milk Research” in 2013, human milk research has increased dramatically in both number and diversity of studies. Anthropological human biologists and biological anthropologists have played key roles in the realization of this research, arguing that evolutionary, developmental, and biocultural perspectives as essential for understanding variation in human milk. The purpose of this review is to highlight human biologists' and biological anthropologists' contributions to our understanding of human milk, often made in broadly collaborative research, as part of the 50th anniversary of the Human Biology Association. In this review, we identify three areas where human biologists have made major contributions: (1) understanding milk as a phenotype, (2) sex-differentiated milk synthesis, and (3) the cultural ecology of milk. We end this review by discussing future research directions and the applied and translational potentials of milk research, calling on human biologists to continue our leadership in the field in the decades to come.

自从我们在2013年发表了“母乳研究中的现场和实验室方法”以来,母乳研究在数量和多样性方面都有了显著的增长。人类人类学生物学家和生物人类学家在这项研究的实现中发挥了关键作用,他们认为进化、发育和生物文化的观点对于理解母乳的变化至关重要。这篇综述的目的是强调人类生物学家和生物人类学家对我们理解母乳的贡献,这些贡献通常是在广泛的合作研究中做出的,作为人类生物学协会50周年纪念的一部分。在这篇综述中,我们确定了人类生物学家做出重大贡献的三个领域:(1)理解牛奶作为一种表型,(2)性别分化的牛奶合成,以及(3)牛奶的文化生态。最后,我们讨论了未来的研究方向以及牛奶研究的应用和转化潜力,呼吁人类生物学家在未来几十年继续在该领域发挥领导作用。
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American Journal of Human Biology
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