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Clinical Observation of Electro acupuncture Combined with Early Rehabilitation Training to Treat Hypertensive Cerebral Hemorrhage in Basal Ganglia 电针结合早期康复训练治疗基底节区高血压脑出血的临床观察
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16304136917582
Wei Wei, T. Qin, Wang Yafen, Zeng Lang, Man-feng Liao
In this study, we investigated the clinical efficacy and poor prognosis of patients with limb disorders after the operation of hypertensive cerebral hemorrhage, using the treatment of removing blood stasis and Shengxin acupuncture combined with early rehabilitation training using a randomized trial. A total of 100 patients with hypertensive intracerebral hemorrhage who underwent surgery in our hospital from May 2019 to May 2021 were selected and divided into control group were treated with early rehabilitation training, and the intervention group was treated with acupuncture for removing blood stasis and promoting new acupuncture based on the control group. We observed that there was no significant difference in the evaluation of limb function recovery between the two groups of patients (P>0.05). After the intervention, the modified Ashworth score, FMA score, and B1 index of the two groups were significantly different in the ADL scores and the scores of families and friends support were remarkably improved. The clinical treatment efficiency of the intervention group was 94.00%,significantly higher than that of the control groupof80.00%, and the difference was statistically significant (P<0.05). The study demonstrated that the rehabilitation training combined with removing blood stasis and Shengxin acupuncture is significantly better than rehabilitation training alone to improve postoperative limb dysfunction, daily life and quality of life and is a clinical treatment for hypertension.
本研究采用随机试验的方法,对高血压脑出血术后肢体障碍患者采用化瘀生心针联合早期康复训练治疗的临床疗效及预后进行研究。选择2019年5月至2021年5月在我院行手术治疗的高血压脑出血患者100例,分为对照组进行早期康复训练治疗,干预组在对照组的基础上采用针刺化瘀、推广新针刺治疗。我们观察到两组患者对肢体功能恢复的评价无显著差异(P < 0.05)。干预后,两组患者的改良Ashworth评分、FMA评分和B1指数在ADL评分上均有显著差异,家庭和朋友支持评分均有显著改善。干预组临床治疗有效率为94.00%,显著高于对照组80.00%,差异有统计学意义(P<0.05)。本研究表明,康复训练结合祛瘀生心针刺在改善术后肢体功能障碍、日常生活和生活质量方面明显优于单纯康复训练,是高血压的一种临床治疗方法。
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引用次数: 0
Analysis Of Factors Influencing Acupuncture Clinical Effects: A Systematic Review 影响针灸临床疗效的因素分析:一项系统综述
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16321477053935
Yali Liu, Hong-cheng Jiang, Xiaotong Li, Xingyue Yang
Background: Acupuncture therapy has been widely applied all around the world. But there still lacks high-quality evidence to evaluate its clinical effects, safety and cost-effectiveness, which seriously restricts its further promotion and development. Acupuncture, as an operational intervention, is more complex than drug therapy. Factors involved in the acupuncture operation process, such as individual and interventional factors, may affect clinical effects. Purpose:s Through this systematic review, we attempt to analyze the current status of studies about the key factors influencing clinical effects, so as to provide evidence for the design of acupuncture studies. Methods: A literature research was conducted in six databases until May, 2020. Studies were screened and assessed by two authors independently. Data extraction was made after screening. We extracted the basic information of these studies, including publishing years and countries, population and factors influencing clinical effects.Results: Through the initial search in these six database, 6404 records were retrieved. After duplication and screening, a total of 355 studies were finally included in the qualitative analysis. About 88.5% of these studies were conducted in China with increasing number in the past decades, covering neurological disorders, orthopedic disorders, obstetrical and gynecological diseases, digestive diseases and so on; 239 studies focused on stimulus parameters which may influence effects, accounting for 67.3%, and 128, 44, 39, 32, 15, 11 studies discussed acupoints, patients’ pathological states, individual difference, psychological states, deqi, and other factors separately. Conclusion: There are more and more studies focusing on factors influencing acupuncture clinical effects, including stimulus parameters, acupoints, individual difference, patient pathological and psychological states. Based on this systematic review, several ignored factors should be considered for future researches, and more scientifically and objectively high quality evidence should also be proved.
背景:针灸疗法在世界范围内得到了广泛的应用。但目前仍缺乏高质量的临床疗效、安全性和成本效益评价证据,严重制约了其进一步推广和发展。针灸作为一种手术干预手段,比药物治疗更为复杂。针刺操作过程中涉及的因素,如个体因素和介入性因素,都可能影响临床效果。目的:通过本系统综述,分析影响临床疗效的关键因素的研究现状,为针灸研究的设计提供依据。方法:截至2020年5月,在6个数据库中进行文献研究。研究由两位作者独立筛选和评估。筛选后进行数据提取。我们提取了这些研究的基本信息,包括发表年份和国家、人群和影响临床效果的因素。结果:通过对这6个数据库的初始检索,检索到6404条记录。经过重复和筛选,最终共有355项研究纳入定性分析。其中约88.5%的研究是在中国进行的,并且在过去几十年里数量不断增加,涵盖神经系统疾病、骨科疾病、妇产科疾病、消化系统疾病等;239项研究关注可能影响疗效的刺激参数,占67.3%,128、44、39、32、15、11项研究分别探讨了穴位、患者病理状态、个体差异、心理状态、德气等因素。结论:对针刺临床疗效影响因素的研究越来越多,包括刺激参数、穴位、个体差异、患者病理和心理状态等。在此系统综述的基础上,今后的研究应考虑一些被忽视的因素,并提出更科学、客观、高质量的证据。
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引用次数: 0
A Randomized Clinical Trial of Proton Pump Inhibitors Combined with Traditional Chinese Medicine in the Treatment of Laryngopharyngeal Reflux Disease 质子泵抑制剂联合中药治疗咽喉反流病的随机临床试验
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16321477053845
F. Pei, Weijing Hu, Y. Mao, Y. Zhao
Background:To explore whether combined with TCM based on classical proton pumpinhibitors PPIs therapy can achieve better efficacy for patients withlaryngopharyngeal reflux disease. Methods: There were 150 laryngopharyngeal refluxpatients enrolled and divided into three groups randomly, with 50 cases in each group.Patients in group A were treated with the proton pump inhibitor (PPI) lansoprazole.Patients in group B were treated with lansoprazole combined with Banxia Houpudecoction, and patients in group C were treated with acupuncture treatments and acombination of Chinese and Western medicine. The reflux symptom index (RSI), refluxfinding score (RFS), and quality of life (36 item short form health survey questionnaire)were assessed before and 4 and 8 weeks after treatment. Results: The RSI and RFSscores of the three groups were significantly reduced after treatment (P < 0.001). Ingroup B and C, they were lower than in group A at 8 weeks (P < 0.01). The SF 36 scoreof 3 groups increased after treatment. At both 4 and 8 weeks (P < 0.001), and patientsin groups B and C scored higher than patients in group A (P < 0.001). The total effectiverate of group B and group C was higher than that of group A (P < 0.05). Conclusion:All three treatments have therapeutic effects on the disease, but the efficacy of a PPIalone is not as good as the combined treatments’ efficacies. Moreover, PPI combinedwith Banxia Houpu decoction and/or acupuncture treatment substantially affects lifeimprovement.
背景:探讨以经典质子泵抑制剂PPIs治疗咽喉反流病患者是否能取得更好的疗效。方法:选取150例咽喉反流患者,随机分为3组,每组50例。A组患者给予质子泵抑制剂兰索拉唑治疗。B组采用兰索拉唑联合半夏厚朴汤治疗,C组采用针刺治疗和中西医结合治疗。分别于治疗前、治疗后4周和8周评估反流症状指数(RSI)、反流发现评分(RFS)和生活质量(36项简短健康调查问卷)。结果:三组患者治疗后RSI、rfs评分均显著降低(P < 0.001)。8周时,B、C组均低于A组(P < 0.01)。治疗后3组SF 36评分均升高。在4周和8周时(P < 0.001), B组和C组患者的评分高于A组患者(P < 0.001)。B、C组总有效率均高于A组(P < 0.05)。结论:三种治疗方法对该病均有治疗效果,但单用ppii的疗效不如联用。此外,PPI联合半夏厚朴汤和/或针灸治疗可显著改善生活。
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引用次数: 0
THE EFFECTIVENESS OF ELECTRO-ACUPUNCTURE IN OVARIAN ISCHEMIA REPERFUSION INJURY 电针治疗卵巢缺血再灌注损伤的疗效观察
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16264625521781
S. Keskin, D. Keskin, M. Değermenci, H. Hanci, Nuket Göçmen Karabekir, M. Atak, O. Baş
Electro-acupuncture is widely used in gynecology. Adnexal torsion is an important threat to ovarian reserves in women of reproductive age. This is the first study to investigate whether electro-acupuncture is beneficial in protecting ovarian reserves in case of adnexal torsion resulting in reperfusion injury. Thirty-two female Wistar Albino rats were randomized into four groups: the first group—sham operation, the second group—torsion/detorsion model, the third group—pre-acupuncture + torsion/detorsion + post-acupuncture, and the fourth group—torsion/detorsion + post-acupuncture. The acupoints used were CV4 and bilateral SP6, Ex-CA1, Kid3, and ST36. In the third group, the acupoints were needled for two weeks before torsion, continuing for a further two weeks after torsion. In the fourth group, needling began after torsion and was maintained for two weeks. Both histological and biochemical parameters indicating ovarian reserves showed that electro-acupuncture applied to the above points exhibited an ameliorating effect on ovaries injured during ischemia/reperfusion. Electro-acupuncture may be capable of protecting against and preventing ischemia/reperfusion injury in case of ovarian torsion.
电针广泛应用于妇科。附件扭转是育龄妇女卵巢储备的重要威胁。这是第一个研究电针是否有利于在附件扭转导致再灌注损伤的情况下保护卵巢储备的研究。将32只雌性Wistar Albino大鼠随机分为4组:第一组(假手术)、第二组(扭转/扭转模型)、第三组(针刺前+扭转/扭转+针刺后)、第四组(扭转/扭转+针刺后)。穴位为CV4及双侧SP6、Ex-CA1、Kid3、ST36。第三组在扭转前2周针刺穴位,扭转后继续针刺穴位2周。第四组在扭转后开始针刺,维持两周。卵巢储备的组织学和生化指标显示,电针对卵巢缺血再灌注损伤有改善作用。电针对卵巢扭转的缺血再灌注损伤有一定的保护和预防作用。
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引用次数: 0
Retesting Conjecture of Acupuncture in Traditional Chinese Medicine Theory 中医理论中针灸猜想的再检验
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16273277361777
Tian-Qi Wang, Ya-jie Wang, Si-Tong Xu
This study proposes the following hypothesis based on studies from various aspects and various historical periods in acupuncture: meridians and collaterals are a continuous, interwoven and ordered system of cells with the same active vibration frequency that guides human nerve activity and blood circulation, and acupuncture can temporarily open, unblock or shut such a system. Yin and Yang depend on the acidity and alkalinity of the internal and external liquid of cells caused by the human body after ingestion of food or influenced by the environment. Traditional Chinese medicine can help the human body adjust the acid-base balance, which is to say, adjust the imbalance state of Yin and Yang. The structure of functional active groups determines the efficacy of traditional Chinese medicine, and the structure can be predicted by using the principle of topology to play a role in the treatment of the corresponding target.
本研究根据针灸各方面、各历史时期的研究,提出以下假设:经络是一个连续、交织、有序的细胞系统,具有相同的主动振动频率,引导人体神经活动和血液循环,针灸可以暂时打开、解除或关闭这个系统。阴阳取决于人体在摄入食物后或受环境影响而产生的细胞内外液的酸碱度。中医可以帮助人体调节酸碱平衡,也就是说,调节阴阳不平衡的状态。功能活性基团的结构决定了中药的疗效,利用拓扑学原理可以预测其结构对相应靶点的治疗作用。
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引用次数: 0
Improvement of Acupuncture Therapy on Relapse of P atients with G outy A rthritis: A Pairwise and Bayesian Network Meta analysis 针刺治疗改善P患者G型A型关节炎复发:两两及贝叶斯网络Meta分析
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16298112109457
Zhihui Li, Min Chen, Chun-lin Tang
Objective: The aim of this study is to investigate the impact of acupuncturetherapy on relapse of patients with gouty arthritis (GA). Methods: “gout ORgouty arthritis” AND “a cupuncture therapy OR acupuncture OR moxibustionOR electroacupuncture OR fire needle OR acupotomology OR blood lettingpuncture OR plum blossom needle” were used as search strategies forsearching related studies. Twenty two studies involving 2394 patient s wereenrolled in this research through the analysis of databases of CNKI, Wanfang,VIP, PubMed, Embase and Cochrane Library. Results: The results of pairwise metaanalysis and network meta analysis (NMA) indicated that patients withacupuncture therapy had a significantly lower relapse rate (RR) compared withthose without acupuncture therapy (OR = 0.21, 95% CI: 0.16 0.26, P <0.00001); the follow up time (TFU) and serum urate concentration (SUA)before treatment had no significant effect on the reductio n of RR caused byacupuncture therapy (P > 0.05); and patients treated with acupuncture plusWestern medicine (WM) had the lowest RR (surface under the cumulativeranking [SUCRA] = 85.0%), followed by acupuncture plus traditional Chinesemedicine (TCM, SUC RA = 73.5%), acupuncture only (SUCRA = 72.8%),fourthly acupuncture plus TCM and WM (SUCRA = 33.0%), then TCM(SUCRA = 28.7%), finally WM (SUCRA = 7.0%). Conclusion: Our findingmay facilitate the application of acupuncture therapy in patients with GA. Ourresearch also offered some information for the future research.
目的:探讨针刺治疗对痛风性关节炎(GA)复发的影响。方法:以“痛风性关节炎”和“针刺、针灸、电针、火针、针刀、放血、梅花针”为检索策略,检索相关研究。通过对中国知网、万方、维普、PubMed、Embase、Cochrane图书馆等数据库的分析,纳入22项研究,涉及患者2394例。结果:两两荟萃分析和网络荟萃分析(NMA)结果显示,针灸治疗组复发率(RR)明显低于未针灸治疗组(OR = 0.21, 95% CI: 0.16 0.26, P 0.05);针刺加西药(SUCRA)治疗的RR最低(累计排序表下[SUCRA] = 85.0%),其次为针刺加中药(中医,SUCRA = 73.5%)、单纯针灸(SUCRA = 72.8%)、针刺加中西医(SUCRA = 33.0%)、中医(SUCRA = 28.7%)、西医(SUCRA = 7.0%)。结论:本研究结果有助于针刺治疗GA的临床应用。我们的研究也为今后的研究提供了一些信息。
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引用次数: 0
Clinical E ffect of Pressing Needle on Nocturnal Enuresis in Children 按针治疗儿童夜间遗尿的临床疗效观察
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16321477053872
Jiao Rong, J Zhang, Jing Li, Junzhong Sun, Changying Yi, Meiling Fan
Objective:With the fast dev elopment of economy and culture, medical professionalsand parents are paying more and more attention to nocturnal enuresis (NE) since it raisedthe negative impact on children’s health and imposes a long term burden on families.The present clinical investigation aims to evaluate the clinical effect of pressing needleon nocturnal enuresis in children through a randomized controlled clinical trial.Materials andMethods: A total of 120 children with nocturnal enuresis were randomlyassigned into pressing needle group, desmopressin group and pills Capsule group, 40cases in each group. The children in pressing needle group were treated with pressingneedles, and those in the desmopressin group and Suoquan pills were orallyadministrated with desmopressin and Suoquan pills, respectively. Combined behavioraltherapy was also given in all the three groups during the treatment. Enuresis frequency,degree of arousal, functional b ladder capacity (FBC) and postvoid residual urine volume(PRUV) were employed as the indicators to evaluate the clinical efficacy in the threegroups. After 6 months of follow up, the recurrence rate of the three groups was alsoanalyzed for efficacy assessment.Results:The total responsive rate in pressing needle group was 95.0%, which was higherthan 87.5% of Suoquan pills group (p < 0.05), and significantly higher than 77.5% of desmopressin group (p < 0.01)desmopressin group (p < 0.01).. The frequency of enuresis was significantly The frequency of enuresis was significantly lowered after lowered after treatment (p < 0.01), concurrently with an evident improvement in arousal levels in all treatment (p < 0.01), concurrently with an evident improvement in arousal levels in all of the three groups (p < 0.01), and the interof the three groups (p < 0.01), and the inter--group difference in postgroup difference in post--treatment enuresis treatment enuresis frequencyfrequency and arousal level between pressing needle group and thand arousal level between pressing needle group and the other two groups was e other two groups was also statialso statistically significant (p < 0.05).stically significant (p < 0.05). The recurrence rate of pressing needle group, The recurrence rate of pressing needle group, desmopressin group and Suoquan pills group was 7.89%, 48.39% and 22.86%, desmopressin group and Suoquan pills group was 7.89%, 48.39% and 22.86%, respectively, with a difference which was statistically significant betrespectively, with a difference which was statistically significant between pressing needle ween pressing needle group and desmopressin group (p < 0.01), but not between pressing needle group and group and desmopressin group (p < 0.01), but not between pressing needle group and Suoquan pills group (p > 0.05). Suoquan pills group (p > 0.05). Conclusion: Conclusion: Pressing needle treatment showed a Pressing needle treatment showed a substantial clinical effect on enuresis in children by improving the bladsubst
目的:随着经济文化的快速发展,夜遗尿症对儿童健康的不良影响和给家庭带来的长期负担越来越受到医学界和家长的重视。本临床研究旨在通过随机对照临床试验,评价按针夜间遗尿治疗儿童的临床效果。材料与方法:将120例夜间遗尿患儿随机分为压针组、去氨加压素组和药丸胶囊组,每组40例。按压针组患儿给予按压针治疗,去氨加压素组患儿口服去氨加压素,锁泉丸口服锁泉丸。三组患者在治疗期间均给予联合行为治疗。以遗尿次数、唤醒程度、功能b梯容量(FBC)、空后残尿量(PRUV)作为评价三组患者临床疗效的指标。随访6个月后,分析三组患者的复发率,评价疗效。结果:按压针组总有效率为95.0%,高于锁泉丸组87.5% (p < 0.05),显著高于去氨加压素组77.5% (p < 0.01)和去氨加压素组(p < 0.01)。遗尿频次经治疗后均显著降低(p < 0.01),同时各治疗组唤醒水平均显著改善(p < 0.01),三组均显著改善唤醒水平(p < 0.01),三组间差异有统计学意义(p < 0.01)。压针组与其他两组治疗后遗尿次数、尿频、唤醒水平、手唤醒水平组间组间差异均为,其他两组间差异均有统计学意义(p < 0.05)。差异有统计学意义(p < 0.05)。压针组复发率、压针组、去氨加压素组、锁泉丸组复发率分别为7.89%、48.39%、22.86%,去氨加压素组、锁泉丸组复发率分别为7.89%、48.39%、22.86%,差异均有统计学意义,压针组与去氨加压素组间压针组复发率差异均有统计学意义(p < 0.01);按压针组与去氨加压素组间无差异(p < 0.01),按压针组与锁泉丸组间无差异(p < 0.05)。锁泉丸组(p < 0.05)。结论:结论:按压针治疗通过改善膀胱功能、增强膀胱功能、增加膀胱FBC、降低膀胱PRUV、增强膀胱FBC增加、降低膀胱PRUV、提高唤醒程度、降低复发率,改善儿童遗尿的膀胱实质临床效果,按压针治疗儿童遗尿具有显著的临床效果。因此,建议提高唤起程度,降低复发率
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引用次数: 0
THE PLANT CONSCIOUSNESS: UNDERSTANDING AND DEVELOPING PROTO-LANGUAGES BETWEEN PLANTS AND HUMANS 植物意识:理解和发展植物与人类之间的原始语言
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16341481788230
S. Turini, Momir Dunjic, B. Vitosevic, Tatjana Novakovic, M. Dunjic, D. Krstić, Katarina Dunjić
Plants are among the oldest and most complex organisms on our world. The complexity lies, first of all, from the cellular point of view, which has a greater compartmentalization than the animal cell. Also evolved as terrestrial organisms, plants have developed complex forms of electrochemical communication, developed to the point of suggesting that plants possessed a sort of nervous system, similar to that found in the animal world and in organisms with a high degree of evolution. Over the course of history, numerous researchers, especially in the last century, have alternated trying to penetrate the functional complexity of plants, obtaining results that allowed to tip the scales towards the presence not only of a nervous system, but a complex processing capacity, comparable to a consciousness. The experiment described here, using a polygraphic apparatus connected to an artificial intelligence computerized processing system, made it possible to evaluate the physiopathological responses of a plant subjected to external stimuli of an invasive and non-invasive nature. The technique involved addressing the vegetable “directly” during the experimentation. The results obtained have highlighted a logical succession of responses, which have allowed us to conclude that plants possess an advanced capacity for processing external stimuli and also of the human voice.
植物是地球上最古老、最复杂的生物之一。复杂性在于,首先,从细胞的角度来看,它比动物细胞具有更大的区隔性。同样是作为陆生生物进化而来的,植物已经发展出复杂的电化学交流形式,发展到某种程度,表明植物拥有一种神经系统,类似于动物世界和高度进化的生物体中发现的神经系统。在历史的进程中,许多研究者,特别是在上个世纪,交替地试图穿透植物功能的复杂性,获得的结果使天平向不仅存在神经系统,而且存在复杂的处理能力,可与意识相媲美。这里描述的实验,使用连接到人工智能计算机处理系统的多测仪,使得评估植物受到侵入性和非侵入性外部刺激的生理病理反应成为可能。这项技术涉及在实验过程中“直接”处理蔬菜。所获得的结果突出了反应的逻辑序列,这使我们得出结论,植物具有处理外部刺激和人类声音的先进能力。
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引用次数: 0
The Effectiveness and Safety of Chemical Drugs Combined with Acupuncture for Alzheimer’s Disease: A Systematic Review and Meta-Analysis 化学药物联合针灸治疗阿尔茨海默病的有效性和安全性:一项系统综述和meta分析
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16321477053881
Shenghua Yu, Hongjie Liu, Li Xu, Yan Zhang, Yan Ma, Hong Zheng, Caijun Tian, Zhe Zhang
Introduction: Acupuncture has been applied with chemical drugs to treat Alzheimer’s disease (AD) in the clinic. Whether such combination is effective and safe should be studied although it is recommended by some researchers.Methods: To explore the effectiveness and safety of acupuncture combined with the chemical drugs for AD, databases like PubMed, Web of Science were searched to retrieve randomized controlled trials (RCTs) on AD treated with acupuncture and chemical drugs to perform meta-analysis. The risk of bias in each study was assessed using the Cochrane Risk of Bias scale. Meta-analysis was performed using RevMan 5.3.Results: Five studies were included in which only donepezil combined with acupuncture was evaluated. Acupuncture combined with donepezil showed a significant difference in effectiveness rate [RR=1.45, 95% CI (1.19, 1.77), P=0.0002] compared with donepezil. On the comparison of mini-mental state examination (MMSE) score and Alzheimer's disease assessment scale cognitive subscale (ADAS-Cog) score there was no difference. However, after one trial with severe AD patients was removed, acupuncture combined with donepezil showed better effect than donepezil alone. Conclusion: Acupuncture combined with donepezil could work on AD at the early stage or with mild AD, implying that acupuncture could be a complementary therapy for AD at early stage or with mild condition. Besides, scalp acupuncture seems to be more effective on improving cognitive function. However, this conclusion must be considered cautiously, given the small sample size and lack of trials of high quality. Therefore, more high-quality, multicenter, prospective, RCTs with large sample sizes are needed to further clarify the effect of acupuncture combined with chemical drugs for AD.
针灸已被应用于临床治疗阿尔茨海默病(AD)的化学药物。尽管一些研究者建议这样做,但这种组合是否有效和安全还有待研究。方法:为探讨针刺联合化学药物治疗AD的有效性和安全性,检索PubMed、Web of Science等数据库,检索针刺联合化学药物治疗AD的随机对照试验(rct),进行meta分析。使用Cochrane偏倚风险量表评估每项研究的偏倚风险。采用RevMan 5.3进行meta分析。结果:纳入了5项仅评价多奈哌齐联合针灸的研究。针刺联合多奈哌齐与多奈哌齐相比,有效率有显著差异[RR=1.45, 95% CI (1.19, 1.77), P=0.0002]。最小精神状态检查(MMSE)评分与阿尔茨海默病评估量表认知亚量表(ADAS-Cog)评分比较无差异。然而,在一项针对重度AD患者的试验中,针刺联合多奈哌齐的效果优于单用多奈哌齐。结论:针刺联合多奈哌齐对早期或轻度AD均有疗效,提示针刺可作为早期或轻度AD的补充治疗。此外,头皮针灸似乎对改善认知功能更有效。然而,考虑到样本量小,缺乏高质量的试验,必须谨慎考虑这一结论。因此,需要更多高质量、多中心、前瞻性、大样本量的随机对照试验来进一步阐明针灸联合化学药物治疗AD的效果。
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引用次数: 1
Buccal Acupuncture Combined with Stellate Ganglion Block in the Treatment of Intractable Vertigo Syndrome: A Case Report 口针联合星状神经节阻滞治疗难治性眩晕综合征1例
IF 0.3 4区 医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2021-01-01 DOI: 10.3727/036012921x16264625521754
Wenguang Deng, Yuenong Zhang, Jian Xu, J. Ye
Intractable vertigo syndrome can be diagnosed after failure of routine treatments for benign paroxysmal positional vertigo (BPPV). Stellate ganglion block can be used in patients who do not respond to oral medication. However, buccal acupuncture combined with stellate ganglion block in the treatment of intractable vertigo syndrome has not been described yet. In this case report, we describe a patient who showed good response to combined treatment with buccal acupuncture and stellate ganglion block
顽固性眩晕综合征可在常规治疗失败后诊断为良性阵发性位置性眩晕(BPPV)。星状神经节阻滞可用于对口服药物无反应的患者。然而,口腔针刺联合星状神经节阻滞治疗顽固性眩晕综合征的研究尚未见报道。在这个病例报告中,我们描述了一个病人,他对口腔针灸和星状神经节阻滞联合治疗表现出良好的反应
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Acupuncture & Electro-Therapeutics Research
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