Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique最新文献

{"title":"Validation of the French version of the Insomnia Severity Index in a population with psychiatric disorders and sleep complaints.","authors":"Emilie Stern, Marie Chamontin, Julia Maruani, Stephane Mouchabac, Jean-Arthur Micoulaud Franchi, Sibylle Mauries, Pierre A Geoffroy","doi":"10.1016/j.encep.2025.04.003","DOIUrl":"https://doi.org/10.1016/j.encep.2025.04.003","url":null,"abstract":"<p><p>Insomnia disorder is a major health concern, particularly among patients with mood disorders. This study validates the translated version of the Insomnia Severity Index (ISI) in a French population with psychiatric disorders, particularly mood disorders. The ISI was completed by 260 patients with sleep complaints comorbid with psychiatric disorders, including 209 patients with mood disorders. The majority of participants were women (n=168), and the most diagnosed condition in the population was unipolar mood disorder (n=170). Internal and external validity analyses validated the scale's reliability and its validity in relation to sleep quality and a diagnosis of insomnia made by a sleep psychiatrist. These results support the use of the French translation of the ISI in a French population with psychiatric disorders.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antinuclear antibodies profiling in Moroccan patients with schizophrenia: A single center study.","authors":"Yassmine Kassal, Aboubaker El Hessni, Abdelhalim Mesfioui, Khadija Fritah, Naila Nakidi, Wahid Boukouaci, Amine Rkhaila, Jihane Bouassida, Siham Belbachir, Fouad Laboudi, Abderrazak Ouanass, Marion Leboyer, Ryad Tamouza, Naima Arji","doi":"10.1016/j.encep.2025.05.001","DOIUrl":"https://doi.org/10.1016/j.encep.2025.05.001","url":null,"abstract":"<p><strong>Objectives: </strong>The present study investigates the prevalence of antinuclear autoantibodies among Moroccan patients with schizophrenia compared to healthy controls and examines the potential associations between the presence of antinuclear autoantibodies and selected sociodemographic and clinical characteristics of patients with schizophrenia.</p><p><strong>Methods: </strong>A cross-sectional assessment was conducted between May 2020 and December 2022. The study involved a total of 157 patients who were diagnosed with schizophrenia and admitted to the Ar-Razi Psychiatric Hospital of Ibn Sina University Hospital Center of Rabat, Morocco. A total of 115 healthy controls (blood donors) were recruited from the transfusion center of Kenitra, Morocco. Antinuclear autoantibodies screening was performed by an indirect immunofluorescence assay (IFA) using HEp-2 cells/liver (Monkey), and 16 specificities of nuclear antigens (ENA) were tested using immunodot assay on an automated platform.</p><p><strong>Results: </strong>The prevalence of antinuclear autoantibodies was significantly higher in patients as compared to healthy control (35 vs. 12.7% with P<0.05) suggesting strongly underlying autoimmune processes in the studied patients. Among the 55 samples tested positive for antinuclear autoantibodies in patients, a total of 29 samples had a positive immunodot result against the following antigens: Jo1, SSA, SSB, Ro 52, AMA-M2, PM-Scl, Sm and Sm/RNP. Logistic regression analysis identified tobacco consumption as the only significant predictor of positive antinuclear autoantibodies (B=2.179, P=0.018).</p><p><strong>Conclusion: </strong>This preliminary study provides original data on the prevalence of antinuclear autoantibodies in Moroccan patients with schizophrenia and reveals a strong association between tobacco consumption and antinuclear autoantibodies positivity. The present findings replicate the previously reported association between autoimmune processes and schizophrenia in other geographical areas and warrant extension to other circulating autoantibodies towards a full profiling of autoimmunity in Moroccan patients with schizophrenia.</p>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatrists’ beliefs, awareness, and attitudes toward gender variance: A French cross-sectional study","authors":"Ilona Lemaitre ,&nbsp;Lucie Jurek ,&nbsp;Ludovic Souiller","doi":"10.1016/j.encep.2024.05.007","DOIUrl":"10.1016/j.encep.2024.05.007","url":null,"abstract":"<div><h3>Objectives</h3><div>The evolution of knowledge and recommendations concerning transgender health has led to various representations, especially for health professionals, that can influence the medical management of transgender individuals. The main objective of this study was to explore the representation of psychiatrists in France regarding gender variance. The secondary objective was to compare these data based on their characteristics.</div></div><div><h3>Methods</h3><div>This is a cross-sectional observational study based on the distribution in April 2022 of a questionnaire to psychiatrists and psychiatric residents in France. The questionnaire was developed after exploring the results of qualitative studies in the scientific literature.</div></div><div><h3>Results</h3><div>Among 359 respondents, 181 were psychiatric residents and 178 were senior psychiatrists. Ninety percent had already met a transgender person in their professional practice. The representations observed among the respondents were heterogeneous. Most respondents did not consider “transgenderism” a symptom of a psychiatric disorder, and nearly all respondents used the gender and name their patients ask for. About 60% reported insufficient knowledge about “transgenderism”, with 86% considering that they had not been trained to adequately support transgender people.</div></div><div><h3>Conclusions</h3><div>The study reveals that representations, although weakened by a lack of knowledge recognized by psychiatrists, favor a non-pathologizing apprehension of gender variance and recognition of the importance of respecting gender diversity and self-determination. The heterogeneity of representations, as well as the high prevalence of professionals who describe a lack of knowledge, skills, and training, support the need for guidelines and the integration of evidence-based knowledge about gender variance into the psychiatric curriculum.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 293-299"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning to observe art to better understand the patients: A pilot study","authors":"Ismaël Conejero ,&nbsp;Hélène Lorblanchet ,&nbsp;Émilie Olié ,&nbsp;Philippe Courtet","doi":"10.1016/j.encep.2024.04.002","DOIUrl":"10.1016/j.encep.2024.04.002","url":null,"abstract":"<div><h3>Objectives</h3><div>We describe an artwork observation training program proposed to the first-year psychiatry residents in the school of medicine of Montpellier-Nîmes (Université de Montpellier). This course aimed at improving the ability to observe, tolerate ambiguity in healthcare, work as a team, communicate, and develop empathy. We also evaluated the impact of this program on the enhancement of emotional and communication skills in a pilot study.</div></div><div><h3>Materials and methods</h3><div>The artwork observation program based on Visual Thinking Strategies consisted of three sessions of ninety minutes involving two groups of eight medical students. First-year volunteer psychiatry residents were recruited. Before the sessions participants completed the Groningen Reflection ability Scale to evaluate reflection skills. Then, all the participants examined paintings and drawings of the Atger collection, were encouraged to observe carefully, and to engage in active group discussion by means of a structured questioning. Following the session, participants responded to a short survey to assess potential improvement of socio-emotional and communication skills.</div></div><div><h3>Results</h3><div>Fifteen psychiatry residents participated in the pilot study, eight were males. The median age was twenty-five years. The artwork observation program was well accepted by the participants. All the respondents reported improvement of emotional and communication skills, except regarding three empathy items, including the ability to feel the suffering of others which was increased only for 62% of respondents.</div></div><div><h3>Discussion</h3><div>Our program relying on Visual Thinking Strategies may improve the ability to observe carefully, to perceive the mental states of others, and to tolerate uncertainty. Training of such skills may encourage the adoption of self-reflective attitudes.</div></div><div><h3>Conclusions</h3><div>Such an artistic innovative program should be extended to undergraduate students in medical curriculum.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 255-260"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological first aid in operation for military healthcare providers : a study on pre-deployment training","authors":"Frédérique Gignoux-Froment ,&nbsp;Emeric Saguin ,&nbsp;Cécile Gorin ,&nbsp;Marianne Daudin ,&nbsp;Sophie Annette ,&nbsp;Julia Salomé ,&nbsp;Mathieu Boutonnet ,&nbsp;Luc Aigle ,&nbsp;Pierre-Éric Schwartzbrod ,&nbsp;Stéphane Travers ,&nbsp;Bertrand Lahutte ,&nbsp;Marie-Dominique Colas","doi":"10.1016/j.encep.2024.05.005","DOIUrl":"10.1016/j.encep.2024.05.005","url":null,"abstract":"<div><h3>Introduction</h3><div>During operational missions, while the management of physical injuries in the field remains the priority, the identification of operational incapacity of psychological origin is necessary as it is equally crucial for the safety of the individual, the group and the mission. The French Military Health Service has developed a Psychological First Aid Training in Operation (PFATO) course based on relational simulations, for military service members. The aim is to identify the early signs of psychological distress in a comrade and to adopt an adapted and protective attitude. PFATO training is also offered to healthcare providers.</div></div><div><h3>Methods</h3><div>We conducted a descriptive cross-sectional study using a self-administered online questionnaire which was sent after deployment to all physicians or nurses trained in PFATO between July 2019 and July 2021 (<em>n</em> <!-->=<!--> <!-->80). The main objective of our work was to evaluate the relevance of this awareness training among physicians and nurses and to identify specific complementary expectations in operational psychiatry for this population.</div></div><div><h3>Results</h3><div>We obtained a response rate of 55%. Significantly, 21.62% of participants used PFATO during their last deployment and another 20% observed a team member using PFATO. The circumstances of use as reported by participants included acute stress related to combat, conflict with hierarchy or comrades, and suicidal crisis. Among those who used PFATO, the training helped 87.5% of them to identify signs of psychological distress and 100% of them to assist combatants . All respondents stressed the added value of practical simulations during PFATO education. Moreover, this study also makes it possible to identify adaptations needed to optimize this module for healthcare providers.</div></div><div><h3>Conclusion</h3><div>The results suggest the value for healthcare provider of training in first-response psychological care using relational simulation based on the model of raising awareness about PFATO.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 285-292"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicide attempts in Martinique and Reunion Island and appointments no-show","authors":"Comsar Ndiaye ,&nbsp;Antone Messiah ,&nbsp;Erick Gokalsing ,&nbsp;Nelly Lislet ,&nbsp;Claire Gillet ,&nbsp;Eric Rene ,&nbsp;Noor Atwan ,&nbsp;Louis Jehel ,&nbsp;Michel Spodenkiewicz","doi":"10.1016/j.encep.2024.03.007","DOIUrl":"10.1016/j.encep.2024.03.007","url":null,"abstract":"<div><h3>Objectives</h3><div>Studies on suicidal behaviors in the French overseas territories remain rare. Although mental health resources are limited, some patients identified as being at risk of suicide do not attend the specialist consultations scheduled after identification or screening. Thus, the objective of our study was, firstly to provide a descriptive profile of patients followed up for a suicide attempt in Martinique and Reunion Island, and secondly to explore the risk factors associated with appointments no-show during follow-up.</div></div><div><h3>Methods</h3><div>We conducted an ancillary retrospective cross-sectional study using data from the APSOM study. Data were collected on 255 patients aged at least 16, admitted to hospital emergency departments after a suicide attempt and followed up in ambulatory care, including 137 in Martinique and 118 in Reunion Island. The characteristics of the sample were described by means [min, max] and proportions [95% confidence intervals]. Differences according to the presence of appointments no-show or not were analyzed using comparison tests of means and percentages (Chi², Fisher and Wilcoxon). Factors associated with appointments no-show were analyzed using a bootstrapped multivariate logistic regression model.</div></div><div><h3>Results</h3><div>The mean age of patients was 35 years [16–84 years]. Women were predominant with a sex ratio of 2.4:1 (71% women). Unemployment affected 37% [28%, 46%] of patients in Martinique and 49% [40%, 59%] in Reunion Island. Psychoactive substances consumption at the time of the suicidal act was observed in 36% [27%, 45%] of patients in Martinique and 34% [26%, 44%] in Reunion Island. The average number of suicide attempts was two per patient [1–20]. Finally, we found no significant association with appointments no-show except for center. Patients from Reunion Island were associated with better compliance than patients from Martinique (OR: 0.20 [0.05–0.65], <em>P</em> <!-->&lt;<!--> <!-->0.012).</div></div><div><h3>Conclusion</h3><div>Our study provides a description of suicide attempts admitted to hospital and followed up in ambulatory care in two French overseas territories and suggests interesting approaches for adapting prevention strategies to the socioeconomic context and cultural realities of these territories, particularly outreach interventions for the most vulnerable patients.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 240-248"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stigma: Bipolar disorder versus cancer, a first-person account","authors":"Marie Milandelle ,&nbsp;Francis Gheysen ,&nbsp;Hélène Verdoux","doi":"10.1016/j.encep.2024.08.002","DOIUrl":"10.1016/j.encep.2024.08.002","url":null,"abstract":"<div><div>The author shares her experience as patient and epidemiologist with bipolar disorder and cancer. She explains why stigma was more challenging to bear with bipolar disorder than with cancer. This account also includes the perspective of two psychiatrists who provided her medical care. This paper aims to share a message of hope with patients with psychiatric diseases and offer some thoughts to help to reduce a patient's stigma.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 338-340"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging correlates of cognitive disorders secondary to electroconvulsive therapy: A systematic review","authors":"Johann Hassan ,&nbsp;Patrice Péran ,&nbsp;Antoine Yrondi","doi":"10.1016/j.encep.2024.08.004","DOIUrl":"10.1016/j.encep.2024.08.004","url":null,"abstract":"<div><h3>Objectives</h3><div>Electroconvulsive therapy is known as an efficient therapy, which is sometimes recommended for the management of severe and resistant depression. However, ECT is associated with cognitive adverse effects. The study of the neurobiological correlates of the cognitive adverse effects of ECT has been covered in few published reviews. However, these mechanisms have been investigated in an increasing number of studies in recent years, particularly in neuroimaging. This systematic review of the literature focuses on correlates between changes in structural or functional neuroimaging and impairment of cognitive functions during the ECT treatment.</div></div><div><h3>Methods</h3><div>We conducted a systematic review of the literature using PRISMA methodology. Searches were performed on the Medline and Web of Science databases using the following equation: “electroconvulsive therapy AND (MRI OR fMRI OR DTI OR neuroimaging) AND depression AND cogniti*”.</div></div><div><h3>Results</h3><div>This article highlights the significant heterogeneity of the results. In structural imaging, approximately 50% of the studies did not report any correlation between volumetric changes and neuropsychological changes. In studies that did highlight a correlation, the latter was mainly reported with changes in the hippocampus. From a functional perspective, we highlighted a correlation between changes in the connectivity of the hippocampal region and cognition.</div></div><div><h3>Conclusion</h3><div>These results demonstrate a growing interest in understanding the neurobiological mechanisms underlying cognitive disorders secondary to ECT treatment. The ultimate aim behind this understanding is to adopt a more effective prevention strategy vis-à-vis these adverse effects.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 308-317"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective study of hepatitis C screening and seroprevalence in the GHU Paris","authors":"Alexandra Pham-Scottez ,&nbsp;Valérie Dauriac-Le Masson ,&nbsp;Oumeyma Ben Dahman ,&nbsp;Armel Toquin ,&nbsp;Amine Benmostefa ,&nbsp;Nabil Hallouche","doi":"10.1016/j.encep.2024.05.002","DOIUrl":"10.1016/j.encep.2024.05.002","url":null,"abstract":"<div><h3>Objectives</h3><div>The prevalence of hepatitis C virus (HCV) has been estimated to be approximately ten times higher in patients with psychiatric disorders, but European data are rare and only two French studies have recently been published on the subject. Our objective was to determine the HCV screening rate and the prevalence of HCV in adult patients hospitalised in the largest French psychiatric hospital.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of all adult patients hospitalised at GHU Paris, from 2019 to 2022, including age, gender, HCV screening, HCV serological status, and the existence of an ICD-10 diagnosis of psychoactive substance use disorder. Descriptive statistics used means<!--> <!-->±<!--> <!-->standard deviations and percentages. Bivariable comparisons used Student's <em>t</em> test and Chi-square test.</div></div><div><h3>Results</h3><div>The overall HCV screening rate was 55.4% and increased over the four years from 37.1% in 2019 to 69.4% in 2022. Patients screened were significantly younger people and with a substance use disorder than unscreened patients. The prevalence of HCV over this 4-year period was 2.8% and remained stable. The HCV-positive patients were significantly more male, older and more likely to have substance use disorders than the HCV-negative patients.</div></div><div><h3>Conclusions</h3><div>We found a prevalence rate of HCV ten times higher than the prevalence in the general population, in line with findings in many other European countries. The eradication of HCV will not be possible without the elimination of this “forgotten reservoir” of the virus. Efforts must be made in psychiatric hospitals to test all patients in order to treat patients suffering from hepatitis C with direct-acting antivirals.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 280-284"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the French version of the preschool form of the social responsiveness scale-second edition (SRS-2-P)","authors":"Marie-Christine Picot ,&nbsp;Cécile Michelon ,&nbsp;Julie Loubersac ,&nbsp;Amaria Baghdadli","doi":"10.1016/j.encep.2024.05.008","DOIUrl":"10.1016/j.encep.2024.05.008","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the psychometric properties of the French form of the preschool social responsiveness scale-2 (SRS-2-P-Fr).</div></div><div><h3>Participants</h3><div>A sample of French children aged 2 to 4 years comprising a group of 93 children with autism spectrum disorder (ASD) and a community control group of 201 children.</div></div><div><h3>Materials and methods</h3><div>Study of internal consistency using Cronbach's α coefficient, convergent validity using correlations with the ADI-R and ADOS-2, and diagnostic accuracy using the receiver operating characteristic curve to determine the best threshold scores useful for screening ASD in preschool children.</div></div><div><h3>Results</h3><div>Good internal consistency (0.78 to 0.98) according to Cronbach's alpha coefficients for the total score and the sub-scores of the SRS-2-P scale. The study of convergent validity showed strong correlations with the total score of the ADOS-2 Toddlers and the communication and reciprocal social interaction sub-scores of the ADI-R. Diagnostic accuracy indicated that the best cut-off score for detecting ASDs was 56 (area under the curve<!--> <!-->=<!--> <!-->0.97, sensitivity 0.925, specificity 0.98).</div></div><div><h3>Conclusion</h3><div>The SRS-2-P-Fr is a valid instrument for the early detection of ASD in preschool children in France and can facilitate diagnosis.</div></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"51 3","pages":"Pages 300-307"},"PeriodicalIF":1.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}