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Impact of follow-up by peer support workers on mental health service users’ global functioning and self-stigmatisation 同伴支持工作者的后续行动对精神卫生服务使用者的整体功能和自我污名化的影响。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.08.011

Objectives

The introduction of the first French professional peer support workers training program. (« Médiateurs de santé pairs en santé mentale ») led to a series of evaluations. After a number of qualitative studies demonstrating benefits of peer support for all stakeholders, our objective was to evaluate its direct effects for users by focusing on repeated quantitative measures: global functioning and self-stigma scores. The hypothesis was that peer support would improve the former and decrease the latter.

Method

The procedure was based on a one-year follow-up of two groups of mental health service users. Both groups received usual care, either with or without additional peer support. All of them were asked to respond to three questionnaires at the beginning of the study and 6 and 12 months later: a sociodemographic and clinical questionnaire, a global functioning scale and a self-stigmatization scale. Samples included 85/64/35 participants at the three stages for the PHM group, and 205/157/105 for the control group.

Results

Peer support improved global functioning. Nevertheless, it had no impact on self-stigmatization scores which remained rather low throughout the observational period.

Conclusions

Despite difficulties concerning follow-up of service users during the course of the study and the reluctance to integrate a new profession based on experiential knowledge, it appears that the hope of recovery can improve global functioning of people with mental disorders. The reasons for low self-stigmatization and its stability over time remain to be explored.

目标:引进法国首个专业同伴支持工作者培训项目。(《关于桑达尔夫妇和桑达尔人的心理健康状况的报告》)导致了一系列评价。在一系列定性研究证明了同伴支持对所有利益相关者的好处之后,我们的目标是通过关注重复的定量测量来评估其对用户的直接影响:全球功能和自我耻辱得分。假设同伴支持会提高前者,降低后者。方法:对两组心理健康服务使用者进行为期一年的随访。两组都接受了常规护理,有或没有额外的同伴支持。所有人都被要求在研究开始时以及6个月和12个月后回答三份问卷:社会人口统计和临床问卷,全球功能量表和自我污名化量表。在三个阶段,PHM组有85/64/35名参与者,对照组有205/157/105名参与者。结果:同伴支持改善了整体功能。然而,它对自我污名化得分没有影响,在整个观察期间,自我污名化得分仍然很低。结论:尽管在研究过程中服务使用者的随访存在困难,并且不愿意基于经验知识融入新的职业,但似乎希望康复可以改善精神障碍患者的整体功能。低自我污名化的原因及其随时间的稳定性仍有待探索。
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引用次数: 0
Impact de la méthode diagnostique du trouble de personnalité borderline sur la réponse aiguë et le risque de rechute précoce chez les individus déprimés majeurs traités par ECT : une revue systématique de la littérature [边缘型人格障碍的诊断方法对接受电痉挛疗法治疗的重度抑郁症患者的急性反应和早期复发风险的影响:系统文献综述]。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.11.021

Introduction

Given the contradictory data available in the literature, the aim of this systematic review was to investigate the impact of the diagnostic method for borderline personality disorder (BPD) on the acute response and the risk of early relapse in major depressed individuals treated with electroconvulsive therapy (ECT).

Method

After a systematic literature review performed during March 2023 in the PubMed-Medline database according to the PRISMA criteria, 47 articles were identified using the keyword algorithm (“Electroconvulsive Therapy” [Mesh] or electroconvulsive therapy) and (“Borderline Personality Disorder” [Mesh] or borderline personality disorder). The inclusion criteria applied for the selection of articles in this systematic review were: (1) articles investigating the impact of BPD on the acute response and/or the risk of early relapse in major depressed individuals (> 18 years old) treated with ECT, (2) diagnosis of BPD and major depressive disorder by validated screening tests and/or systematic psychiatric interviews based on diagnostic criteria of international classification, (3) any type of study (cross-sectional, longitudinal, prospective, retrospective, interventional and experimental), (4) articles written in English or French, and (5) articles published after January 2000. After assessment of the 47 articles based on these inclusion criteria by two authors, seven studies investigating the impact of BPD diagnosed by systematic psychiatric interview or screening tests on the acute response and the risk of early relapse in major depressed individuals treated with ECT were included in this systematic review.

Results

Unlike the three studies diagnosing BPD by screening tests, the four studies diagnosing BPD by systematic psychiatric interview demonstrated a negative impact of this personality disorder on the acute response or the risk of early relapse in major depressed individuals treated with ECT. However, all studies included in this systematic review presented a low level of scientific evidence (cross-sectional epidemiological studies and retrospective cohort studies).

Conclusion

Despite the need for studies of better scientific quality, the results of this systematic review seem to indicate that screening for BPD by systematic psychiatric interview during the pre-ECT assessment and the establishment of adequate therapeutic strategies in case of comorbid BPD could be promising options to allow better acute response and better prevention of early relapses in major depressed individuals treated with ECT.

导言:鉴于文献中存在相互矛盾的数据,本系统性综述旨在研究边缘型人格障碍(BPD)的诊断方法对接受电休克疗法(ECT)治疗的重度抑郁症患者的急性反应和早期复发风险的影响:2023年3月,根据PRISMA标准在PubMed-Medline数据库中进行了系统性文献综述,通过关键词算法("电休克疗法"[Mesh]或电休克疗法)和("边缘型人格障碍"[Mesh]或边缘型人格障碍)确定了47篇文章。本系统综述在选择文章时采用的纳入标准是(1) 研究 BPD 对接受 ECT 治疗的重度抑郁症患者(18 岁以上)的急性反应和/或早期复发风险的影响的文章;(2) 根据国际分类的诊断标准,通过有效的筛查测试和/或系统的精神病学访谈诊断出 BPD 和重度抑郁障碍的文章;(3) 任何类型的研究(横断面、纵向、前瞻性、回顾性、干预性和实验性);(4) 用英语或法语撰写的文章;(5) 2000 年 1 月以后发表的文章。根据这些纳入标准,两位作者对 47 篇文章进行了评估,然后将 7 项研究纳入了本系统性综述,这些研究调查了通过系统性精神病学访谈或筛查测试诊断出的 BPD 对接受 ECT 治疗的重度抑郁症患者的急性反应和早期复发风险的影响:与三项通过筛查测试诊断 BPD 的研究不同,四项通过系统性精神病学访谈诊断 BPD 的研究表明,这种人格障碍对接受 ECT 治疗的重度抑郁症患者的急性反应或早期复发风险有负面影响。然而,纳入本系统综述的所有研究(横断面流行病学研究和回顾性队列研究)均提供了低水平的科学证据:尽管还需要科学质量更高的研究,但本系统综述的结果似乎表明,在ECT治疗前的评估中,通过系统的精神病学访谈筛查BPD,并在合并BPD的情况下制定适当的治疗策略,可能是一种很有前景的选择,可使接受ECT治疗的重度抑郁症患者获得更好的急性反应,并更好地预防早期复发。
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引用次数: 0
Eco-anxiety: An adaptive behavior or a mental disorder? Results of a psychometric study 生态焦虑症:适应行为还是精神障碍?心理测量研究结果。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.08.009

Objective

Eco-anxiety is a complex construct that has been created to grasp the psychological impact of the consequences of global warming. The concept needs a reliably valid questionnaire to better evaluate its impact on the risk of anxiety and depressive disorders. The Eco-Anxiety Questionnaire (EAQ-22) evaluates two dimensions: ‘habitual ecological anxiety’ and ‘distress related to eco-anxiety’. However, a version in French, one of the world's widely spoken languages, was until now lacking. We aimed to translate and validate the French EAQ-22 and to evaluate the prevalence of the level of the two dimensions of eco-anxiety and the relationship with anxiety and depressive symptoms in a representative adult sample of the French general population.

Methods

This study was performed under the auspices of the Institut national du sommeil et de la vigilance (INSV). Participants (18–65 years) were recruited by an institute specialized in conducting online surveys of representative population samples (quota sampling). Two native French speakers and two native English speakers performed a forward-backward translation of the questionnaire. The Hospital Anxiety and Depression scale (HAD) was administered to assess anxiety (HAD-A) and depressive (HAD-D) symptoms and for external validity. Internal structural validity and external validity were analysed.

Results

Evaluation was performed on 1004 participants: mean age 43.47 years (SD = 13.41, range: [19–66]); 54.1% (n = 543) women. Using the HAD, 312 (31.1%) patients had current clinically significant anxiety symptoms (HAD-A > 10) and 150 (14.9%) had current clinically significant depressive symptoms (HAD-D>10). Cronbach's alpha coefficient was 0.934, indicating very good internal consistency. Correlation between EAQ-22 and HAD scores was low (r[1004] = 0.209, P < 0.001), ‘habitual ecological anxiety’ was correlated less with HAD-A and HAD-D than ‘distress related to eco-anxiety’, indicating good external validity.

Conclusion

This study validates the French EAQ-22 and paves the way for using the EAQ-22 as a global tool for assessing eco-anxiety. Further prospective studies are now required to better evaluate the impact of eco-anxiety on the occurrence of anxiety and depressive disorder.

目的:生态焦虑是一个复杂的概念,是为了了解全球变暖的后果所造成的心理影响而提出的。这一概念需要一份可靠有效的问卷,以更好地评估其对焦虑症和抑郁症风险的影响。生态焦虑问卷(EAQ-22)从两个方面进行评估:习惯性生态焦虑 "和 "与生态焦虑相关的痛苦"。然而,作为世界上使用最广泛的语言之一,迄今为止还没有一个法语版本。我们的目的是翻译并验证法文版 EAQ-22,并在法国普通人群中有代表性的成人样本中评估生态焦虑两个维度的普遍程度以及与焦虑和抑郁症状之间的关系:本研究由法国国家疾病与警觉研究所(INSV)赞助进行。参与者(18-65 岁)由一家专门从事代表性人口抽样在线调查(配额抽样)的机构招募。两名母语为法语和两名母语为英语的人员对问卷进行了正向和反向翻译。采用医院焦虑和抑郁量表(HAD)评估焦虑(HAD-A)和抑郁(HAD-D)症状,并进行外部验证。对内部结构效度和外部效度进行了分析:对 1004 名参与者进行了评估:平均年龄 43.47 岁(SD=13.41,范围:[19-66]);54.1%(n=543)为女性。通过使用 HAD,312 名(31.1%)患者目前有明显的临床焦虑症状(HAD-A>10),150 名(14.9%)患者目前有明显的临床抑郁症状(HAD-D>10)。Cronbach'sα系数为0.934,表明内部一致性非常好。EAQ-22与HAD得分之间的相关性较低(r[1004]=0.209,PC结论:本研究验证了法国 EAQ-22 的有效性,并为将 EAQ-22 作为评估生态焦虑的全球工具铺平了道路。现在需要进一步开展前瞻性研究,以更好地评估生态焦虑对焦虑症和抑郁症的影响。
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引用次数: 0
Is mindfulness practice “at risk” of increasing spirituality? Systematic review and critical analysis of a claimed effect 正念练习是否有增加灵性的 "风险"?对声称的效果进行系统回顾和批判性分析。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.11.013

Introduction

Mindfulness meditation has gained prominence in somatic and psychiatric care in several countries including France. Studies have shown its effectiveness in various conditions, in particular the prevention of depressive relapses. However, there are criticisms and concerns about its potential links to Buddhism and spirituality, raising issues of secularism and sectarianism. This issue is particularly conflicting in France with regard its historical and political relationship with secularism.

Objectives

This study aims to assess quantitative data regarding the impact of mindfulness meditation on spirituality and religiosity using quantitative validated scales.

Methods

A systematic review was conducted. PubMed was searched for relevant studies using keywords related to mindfulness and spirituality/religiosity scales. Four scales assessing spirituality were identified: FACIT-sp, INSPIRIT, DSES, and DUREL. Qualitative analysis determined if scale items pertained to spirituality or other topics considered by opponents to mindfulness as “at risk” for deviances or sectarian aberrations. Quantitative analysis assessed the effect size of changes in scale scores before and after mindfulness meditation interventions.

Results

Eighteen studies were analyzed, with varying scales and program durations including 1272 participants. Qualitative analysis showed that most scales contained items related to spirituality as well as “at risk” elements like religion and mysticism. Quantitative analysis revealed that a few studies reported significant increases in spirituality scores following mindfulness meditation, but the clinical relevance of these changes was questioned. In general, control groups had smaller score changes.

Interpretation

While some studies suggest a potential increase in spirituality due to mindfulness meditation, the clinical significance of these findings remains uncertain. Moreover, mindfulness meditation's ties to Buddhism are disputed, and its roots are intertwined with various psychotherapy traditions that incorporate spirituality. The role of secularism in psychotherapy is also debated in France, emphasizing the need for proper use and regulation policy rather than prohibition of mindfulness-based approaches. This study highlights the complexity of assessing the impact of mindfulness meditation on spirituality and religiosity. It suggests that a pragmatic approach focusing on risk and harm reduction may be more suitable than labeling the practice as “at risk”. Further research is needed to clarify these issues in the specific cultural context of France.

简介在包括法国在内的一些国家,正念冥想在躯体和精神治疗方面的作用日益突出。研究表明,正念冥想对各种疾病都有疗效,尤其是在预防抑郁症复发方面。然而,也有人对其与佛教和精神信仰的潜在联系提出了批评和担忧,引发了世俗主义和宗派主义的问题。在法国,这一问题在其与世俗主义的历史和政治关系方面尤为矛盾:本研究旨在使用经过验证的定量量表,评估正念冥想对灵性和宗教性影响的定量数据:方法:进行了系统回顾。使用正念和灵性/宗教信仰量表相关关键词在 PubMed 上搜索相关研究。确定了四种评估灵性的量表:FACIT-sp、INSPIRIT、DSES 和 DUREL。定性分析确定了量表项目是否与灵性有关,或者是否与正念反对者认为 "有可能 "出现偏差或宗派偏差的其他主题有关。定量分析评估了正念冥想干预前后量表分数变化的效应大小:对 18 项研究进行了分析,这些研究的量表和项目持续时间各不相同,共有 1272 名参与者。定性分析显示,大多数量表都包含与灵性有关的项目以及宗教和神秘主义等 "危险 "元素。定量分析显示,有几项研究报告称,正念冥想后灵性得分显著增加,但这些变化的临床相关性受到质疑。一般来说,对照组的得分变化较小:虽然一些研究表明正念冥想可能会提高灵性,但这些研究结果的临床意义仍不确定。此外,正念冥想与佛教的关系也存在争议,其根源与各种包含灵性的心理疗法传统交织在一起。世俗主义在心理疗法中的作用在法国也引起了争论,这强调了正确使用和监管政策的必要性,而不是禁止正念冥想方法。本研究强调了评估正念冥想对灵性和宗教性影响的复杂性。它表明,与将正念冥想贴上 "有风险 "的标签相比,以降低风险和危害为重点的务实方法可能更为合适。在法国的特定文化背景下,还需要进一步的研究来澄清这些问题。
{"title":"Is mindfulness practice “at risk” of increasing spirituality? Systematic review and critical analysis of a claimed effect","authors":"","doi":"10.1016/j.encep.2023.11.013","DOIUrl":"10.1016/j.encep.2023.11.013","url":null,"abstract":"<div><h3>Introduction</h3><p>Mindfulness meditation has gained prominence in somatic and psychiatric care in several countries including France. Studies have shown its effectiveness in various conditions, in particular the prevention of depressive relapses. However, there are criticisms and concerns about its potential links to Buddhism and spirituality, raising issues of secularism and sectarianism. This issue is particularly conflicting in France with regard its historical and political relationship with secularism.</p></div><div><h3>Objectives</h3><p>This study aims to assess quantitative data regarding the impact of mindfulness meditation on spirituality and religiosity using quantitative validated scales.</p></div><div><h3>Methods</h3><p>A systematic review was conducted. PubMed was searched for relevant studies using keywords related to mindfulness and spirituality/religiosity scales. Four scales assessing spirituality were identified: FACIT-sp, INSPIRIT, DSES, and DUREL. Qualitative analysis determined if scale items pertained to spirituality or other topics considered by opponents to mindfulness as “at risk” for deviances or sectarian aberrations. Quantitative analysis assessed the effect size of changes in scale scores before and after mindfulness meditation interventions.</p></div><div><h3>Results</h3><p>Eighteen studies were analyzed, with varying scales and program durations including 1272 participants. Qualitative analysis showed that most scales contained items related to spirituality as well as “at risk” elements like religion and mysticism. Quantitative analysis revealed that a few studies reported significant increases in spirituality scores following mindfulness meditation, but the clinical relevance of these changes was questioned. In general, control groups had smaller score changes.</p></div><div><h3>Interpretation</h3><p>While some studies suggest a potential increase in spirituality due to mindfulness meditation, the clinical significance of these findings remains uncertain. Moreover, mindfulness meditation's ties to Buddhism are disputed, and its roots are intertwined with various psychotherapy traditions that incorporate spirituality. The role of secularism in psychotherapy is also debated in France, emphasizing the need for proper use and regulation policy rather than prohibition of mindfulness-based approaches. This study highlights the complexity of assessing the impact of mindfulness meditation on spirituality and religiosity. It suggests that a pragmatic approach focusing on risk and harm reduction may be more suitable than labeling the practice as “at risk”. Further research is needed to clarify these issues in the specific cultural context of France.</p></div>","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"50 4","pages":"Pages 427-435"},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organization of French outpatient psychiatric clinics and delay to appointment 法国精神病门诊诊所的组织和延迟预约。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.09.005

Objectives

The goals of the study were to obtain a glimpse of the several types of organization of outpatient psychiatric clinics, as well as an overview of delays between a request for and the first appointment. We also look at geographical variability of appointment scheduling delays and assess the impact of the number of new applications on delays.

Methods

We analyzed information collected from a phone survey conducted with the 103 adult outpatient psychiatric clinics of the French region Hauts-de-France. This survey had a one-week inclusion period in November 2022 and focused on the organization and delays before obtaining an appointment.

Results

This study indicates that organizations seem to be homogeneous. Eighty-one outpatient psychiatric clinics (96.4%) receive with scheduled appointments. The initial evaluation by a nurse followed with a proposal for the organization of care seems to be the common practice. It also appears that primary psychiatric structures were capable of providing a response within a reasonable time frame in making a first appointment with a mental health professional. On the other hand, delays were much longer and heterogeneous for first appointments with psychiatrists and psychologists.

Conclusions

The organizations of the outpatient psychiatric clinics of the French region Hauts-de-France seem homogeneous. The evaluation by a nurse followed with a care proposal is the common practice. Primary psychiatric structures are able to provide a response within a reasonable time, with half the centers proposing an appointment with a nurse within 10.0 days.

目的:本研究的目的是了解几种类型的门诊精神科诊所的组织,以及从请求到第一次预约之间的延迟的概述。我们还研究了预约安排延迟的地理差异,并评估了新申请数量对延迟的影响。方法:我们分析了对法国上法兰西地区103家成人门诊精神病诊所进行的电话调查收集的信息。该调查于2022年11月进行,为期一周,重点关注预约前的组织和延误。结果:本研究表明,组织似乎是同质的。81个精神病门诊诊所(96.4%)接受预约。通常的做法是由护士进行初步评估,然后提出护理组织建议。初级精神病机构似乎也能够在合理的时间范围内为初次预约心理健康专业人员提供答复。另一方面,第一次与精神科医生和心理学家会面的延误时间要长得多,而且种类繁多。结论:法国上法兰西地区精神病门诊诊所的组织似乎是同质的。通常的做法是由护士进行评估,然后提出护理建议。初级精神病机构能够在合理的时间内提供回应,一半的中心建议在10天内与护士预约。
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引用次数: 0
COVID-19 crisis and the incidence of hospital admissions for psychosis in France 新冠肺炎危机与法国精神病住院率。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.08.003

Objectives

We aimed to assess the impact of the COVID-19 crisis on the occurrence of new hospital admissions for cases of psychosis in France.

Method

We conducted a retrospective observational study from the French national PMSI database. We included patients hospitalized between 2018 and 2020 with a principal diagnosis of schizophrenia or delusional disorder with no history of psychosis in the previous 10 years. In total, we included 77,172 inpatients at crisis centers and/or in full-time hospitalization at 465 French hospitals. We assessed the number of inpatients during the year of the Covid crisis (2020) and the two years prior (2018, 2019).

Results

The number of inpatients in full-time hospitalization decreased gradually from 2018 to 2020 by 10.6%. This downward trend was observed in all age groups. In contrast, in crisis centers the number of inpatients increased by 13.4% between 2019 and 2020, while a 7.6% decrease was seen between 2018 and 2019. The greatest increase was observed in the 31–60-year age category, and particularly amongst 46–60-year-olds, i.e. 38.0%.

Conclusion

The COVID-19 crisis was associated with an increase in the number of inpatients with a new episode of psychosis in crisis centers but not in full-time hospitalization. The profile of patients in crisis centers was different from that seen in preceding years and included more middle-to-late age adults. Particular attention should be given to this category of patients in the crisis environment to prevent the occurrence of new cases of psychosis in France.

目的:我们旨在评估新冠肺炎危机对法国精神病病例新入院率的影响。方法:我们从法国国家PMSI数据库进行了一项回顾性观察性研究。我们纳入了2018年至2020年间住院的主要诊断为精神分裂症或妄想症的患者,这些患者在过去10年中没有精神病史。我们总共纳入了77172名在危机中心和/或在465家法国医院全职住院的住院患者。我们评估了新冠肺炎危机发生年份(2020年)和前两年(20182019年)的住院人数。结果:从2018年到2020年,全职住院的住院人数逐渐减少了10.6%。所有年龄组都出现了这种下降趋势。相比之下,在危机中心,2019年至2020年间住院人数增加了13.4%,而2018年至2019年间下降了7.6%。31-60岁年龄组的增幅最大,尤其是46-60岁年龄段,即38.0%。结论:新冠肺炎危机与危机中心新发精神病住院人数的增加有关,但与全职住院人数无关。危机中心的患者情况与前几年有所不同,包括更多的中老年人。应特别注意处于危机环境中的这类患者,以防止法国出现新的精神病病例。
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引用次数: 0
Prevalence of depression and protective factors in a population of children aged 8 to 10 years, suffering from specific learning disorders, in a special education and home care service (SESSAD) 在特殊教育和家庭护理服务(SESSAD)中,8至10岁患有特定学习障碍的儿童群体的抑郁症患病率和保护因素。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.08.008

Objectives

Evaluate the prevalence of depression in a population of children aged 8 to 10 years with learning disabilities treated in a Special Education and Home Care Service (SESSAD) and identify the protective factors that might preserve these children from depressive and affective problems.

Methods

Twenty children, aged 8 to 10, with learning disabilities were evaluated prior to their admission in SESSAD. Depression had been assessed through the Multiscore Depression Inventory for Children (MDIC), adapted to the French population as well as their developmental position in relation with their perceptual maturity of their body schema, through the Draw your family drawing. The protective factors were assessed through the qualitative analysis of the stories told on the Draw your family projective drawing and card 4, 9, 20 of The Socialization Test for Children (TSEA). Quantitative data were computed through descriptive statistics and non-parametric tests (Spearman's correlation test) by the jamovi© statistic software (V.2.3.24), and the qualitative data were analyzed through thematic content analysis and lexical text analysis through the TROPES software (V.8.3).

Results

Quantitative data showed for the entire group: (1) a perceptual maturity delay of the body schema in 75% of the sample; (2) a low incidence of depression in this population with, however, 40% of the sample, (aged 8 and 9) displaying a critical threshold for feelings of helplessness. The qualitative analysis of the Draw your family and TSEA stories allowed to underline some of the protective factors against depression and those which refer, in decreasing order, to the social support given by family members, peers, and the emotional substitutes (animals).

Conclusions

This research highlighted the precocity of the feelings of helplessness in this population and the importance given by these children to the social support. These findings and future research on the topic might be used to guide the design and implementation of adjusted interventions addressing both the development of their learning capability and psychological empowerment.

目的:评估在特殊教育和家庭护理服务(SESSAD)中接受治疗的8至10岁学习障碍儿童的抑郁患病率,并确定可能使这些儿童免受抑郁和情感问题影响的保护因素。方法:对20名8至10岁的学习障碍儿童在进入SESSAD之前进行评估。抑郁症是通过儿童多核心抑郁量表(MDIC)进行评估的,该量表适用于法国人群,以及他们的发育位置与他们身体模式的感知成熟度之间的关系,并通过绘制你的家庭图进行评估。通过对“绘制你的家庭投影图”和“儿童社会化测试”(TSEA)卡片4、9、20上讲述的故事进行定性分析,评估保护因素。定量数据由jamovi©统计软件(V.2.3.24)通过描述性统计和非参数检验(Spearman相关性检验)计算,结果:定量数据显示:(1)75%的样本身体图式存在感知成熟延迟;(2) 该人群中抑郁症的发病率较低,但40%的样本(8岁和9岁)显示出无助感的临界阈值。对Draw your family和TSEA故事的定性分析可以强调一些对抗抑郁的保护因素,以及那些按降序指代家庭成员、同龄人和情感替代者(动物)给予的社会支持的因素。结论:本研究强调了该人群中无助感的早熟性,以及这些儿童对社会支持的重视。这些发现和未来对这一主题的研究可用于指导调整干预措施的设计和实施,这些干预措施涉及他们学习能力的发展和心理赋权。
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引用次数: 0
The French National Agency for the Safety of Medicines and Health Products (ANSM) warns doctors about the risks of prescribing valproate to men of reproductive age 法国国家药品和保健品安全局(ANSM)警告医生,给育龄男性开丙戊酸钠处方存在风险。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2024.03.001
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引用次数: 0
Could semaglutide be related to increasing the risk of developing a disordered eating? 塞马鲁肽是否会增加饮食失调的风险?
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.11.022
{"title":"Could semaglutide be related to increasing the risk of developing a disordered eating?","authors":"","doi":"10.1016/j.encep.2023.11.022","DOIUrl":"10.1016/j.encep.2023.11.022","url":null,"abstract":"","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"50 4","pages":"Page 473"},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CSMD1 rs10503253 increases schizophrenia risk in a Tunisian population-group CSMD1 rs10503253在突尼斯人群中增加了精神分裂症的风险。
IF 1.2 4区 医学 Q4 NEUROSCIENCES Pub Date : 2024-08-01 DOI: 10.1016/j.encep.2023.08.002

Objectives

Schizophrenia is a complex and chronic neuropsychiatric disorder. Recent genome-wide association studies have identified several at risk genetic variants, including two single nucleotide polymorphisms, namely the rs10503253 and the rs1270942 respectively located in the CSMD1 and the CFB loci. The present case-control study was designed to assess potential associations between the two variants and the risk of developing schizophrenia and disease severity. Further we demonstrate the relationship between these variants and clinical characteristics in a population-group from Tunisia.

Patients and methods

In total, 216 patients diagnosed with schizophrenia along with176 healthy controls were included in this case–control study. The molecular analysis of the two polymorphisms was performed using tetra the Primer Amplification Refractory Mutation System–Polymerase Chain method. The statistical analysis was done using Compare V2.1 software, and correlations between genetic results and clinical characteristics were examined by Kruskal-Wallis testing.

Results

The frequency of the rs10503253A allele was found significantly higher among patients with schizophrenia as compared to healthy controls and associated with high negative PANSS scores. While no association was found concerning the implication of the rs1270942 variant in schizophrenia risk, a positive correlation with high positive PANSS scores was further observed.

Conclusion

The present finding confirms the previously reported association between the Cub and Sushi multiple Domain 1 rs10503253A allele and the risk to develop schizophrenia and identified the rs1270942 variant as a potential disease risk modifier. Such observations may be important for the definition of the susceptible immunogenetic background in North African individuals at risk to develop mental disorders.

目的:精神分裂症是一种复杂的慢性神经精神障碍。最近的全基因组关联研究已经确定了几个有风险的遗传变异,包括两个单核苷酸多态性,即分别位于CSMD1和CFB基因座的rs10503253和rs1270942。本病例对照研究旨在评估这两种变体与发展为精神分裂症的风险和疾病严重程度之间的潜在关联。此外,我们在突尼斯的一个人群中证明了这些变异与临床特征之间的关系。患者和方法:本病例对照研究共包括216名被诊断为精神分裂症的患者和176名健康对照。用引物扩增难治性突变系统聚合酶链法对两个多态性进行分子分析。使用Compare V2.1软件进行统计分析,并通过Kruskal-Wallis检验检验遗传结果与临床特征之间的相关性。结果:与健康对照组相比,精神分裂症患者rs10503253A等位基因的频率显著较高,并与高阴性PANSS评分相关。虽然没有发现rs1270942变体在精神分裂症风险中的意义相关,但进一步观察到与高阳性PANSS评分呈正相关。结论:本发现证实了先前报道的Cub和Sushi多结构域1 rs10503253A等位基因与精神分裂症发病风险之间的相关性,并确定rs1270942变体是潜在的疾病风险调节剂。这些观察结果对于确定有患精神障碍风险的北非个体的易感免疫遗传背景可能很重要。
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Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique
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