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Intravenous ketamine for suicide ideation in borderline personality and depression 静脉注射氯胺酮治疗边缘型人格和抑郁症患者的自杀意念。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.04.008
Yara Bachir , Raymond Kassab , Caroline Hallal , Colin Charbel Cordahi , Charline El Hachem , Rami Bou Khalil

Objective

This case report explores the efficacy of intravenous Ketamine in treating active suicidal ideation in a 24-year-old female with comorbid major depressive disorder (MDD), borderline personality disorder (BPD), posttraumatic stress disorder (PTSD), and functional neurological disorder (FND).

Case description

The patient, with a history of multiple suicide attempts and treatment-resistant MDD, demonstrated significant improvement following nine intravenous ketamine sessions. The Montgomery-Åsberg Depression Rating Scale score decreased from 45 to 11, accompanied by sustained reductions in impulsivity, irritability, and depressive symptoms.

Discussion

This report highlights ketamine's rapid action on glutamate pathways and its potential benefits in complex psychiatric profiles where traditional treatments like electroconvulsive therapy often fail. A proposed staging model for suicidal behavior management underscores the importance of early intervention with non-classical treatments in high-risk cases.

Conclusion

Intravenous ketamine offers a promising therapeutic option for patients with severe suicidality and comorbidities, warranting further research on its long-term efficacy and safety.
目的:探讨静脉注射氯胺酮治疗1例伴有重度抑郁症(MDD)、边缘型人格障碍(BPD)、创伤后应激障碍(PTSD)和功能性神经障碍(FND)的24岁女性主动自杀意念的疗效。病例描述:患者有多次自杀企图和治疗难治性重度抑郁症的历史,在9次静脉注射氯胺酮后表现出显著改善。蒙哥马利-Åsberg抑郁评定量表得分从45分降至11分,同时冲动、易怒和抑郁症状持续减少。讨论:本报告强调氯胺酮对谷氨酸通路的快速作用及其在复杂精神病学方面的潜在益处,而传统的治疗方法如电休克治疗往往失败。一个提出的自杀行为管理分期模型强调了在高危病例中采用非经典治疗的早期干预的重要性。结论:静脉注射氯胺酮对重度自杀及合并症患者是一种很有前景的治疗选择,值得进一步研究其长期疗效和安全性。
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引用次数: 0
Atypical visual hallucinations in vascular depression following cerebellar stroke 小脑卒中后血管抑制的非典型视幻觉。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.06.001
Hugo Bottemanne , Antoine Wicker , Edouard Baudouin , Julia Korngold , Severine Martin , Nourredine Haddadi , Walid Choucha , Romain Colle , Emmanuelle Corruble
Cerebrovascular abnormalities may predispose, precipitate, or perpetuate depressive symptoms in old adults, supported by the hypothesis of vascular depression. These depressive episodes are sometimes accompanied by atypical neurological symptoms associated with localized vascular lesions in the brain. We present the case of an 84-year-old man with vascular depression who experienced visual hallucinations and dizziness, coinciding with the incidental discovery of a cerebellar stroke. Based on this clinical case, we discuss the hypothesis of perceptual and affective cerebellar functions.
脑血管异常可能使老年人抑郁症状易感、沉淀或延续,这得到血管性抑郁假说的支持。这些抑郁发作有时伴有不典型的神经系统症状,并伴有脑内局部血管病变。我们提出的情况下,84岁的男子血管抑郁谁经历了视觉幻觉和头晕,同时偶然发现小脑卒中。根据这一临床病例,我们讨论了小脑知觉和情感功能的假说。
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引用次数: 0
Experience and qualitative evaluation of two soothing prototypes in psychiatry 精神病学两种抚慰原型的经验与定性评价。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.02.008
Noémie Chataigner , Cynthia Fleury , Valérie Gateau

Objectives

The need for alternatives to restraint and seclusion in psychiatry is widely recognized. To this end, a collaborative research project between patients, caregivers and designers resulted in the production of two containing prototypes (a covering armchair and a sensory totem). The aim of the research project was to understand whether these prototypes offered a calming alternative and could limit the need for restraint.

Method

Semi-structured interviews were carried out as well as participant observations, and feedback forms were given to participants. Qualitative data analysis was integral and inductive, initially thematic and then oriented according to the “type of ward” variable.

Results

The prototypes had beneficial effects on calming and empowering patients; they supported the patient-staff relationship and contributed to team reflexivity. Rather than pathologies, the prototypes responded to appeasement needs and situations of agitation or anxiety. For closed wards, the prototypes were therapeutic and supported patient autonomy in crisis situations. For open wards, they were integrated into the activities offered but needed to be accompanied by caregivers to ensure patient safety.

Discussion

The results prompted discussion on three points: 1) research methods in psychiatry and the need to integrate users in research design; 2) conceptions of autonomy in psychiatric care; 3) the place of sensory rooms and soothing techniques in reducing the use of restraint and seclusion.
目的:在精神病学中,需要替代约束和隔离的方法。为此,患者,护理人员和设计师之间的合作研究项目产生了两个包含原型(覆盖扶手椅和感官图腾)。该研究项目的目的是了解这些原型是否提供了一种平静的选择,并可以限制对约束的需求。方法:采用半结构式访谈和参与者观察,并向参与者发放反馈表格。定性数据分析是整体和归纳的,最初是主题,然后根据“病房类型”变量定向。结果:原型对安抚病人和赋予病人权力有有益的作用;他们支持医患关系,促进团队反思。这些原型不是病态的,而是对安抚需求和激动或焦虑的情况做出反应。对于封闭病房,原型是治疗性的,并支持病人在危机情况下的自主权。对于开放式病房,他们被整合到提供的活动中,但需要护理人员陪同,以确保患者安全。讨论:结果引发了三点讨论:1)精神病学的研究方法和在研究设计中整合用户的必要性;2)精神科护理自主性观念;3)感官室和安抚技术在减少使用约束和隔离方面的地位。
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引用次数: 0
What factors are associated with seclusion in patients with psychosis? 哪些因素与精神病患者的隔离有关?
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.03.004
Husen Ali-Diabacte , Assia Mazari , Eirini Rari , Catherine Martelli , Amine Benyamina , Bruno Romeo

Objective

Seclusion is a measure used as a last resort in psychiatry to manage high-risk situations of hetero- or self-agression. However, few studies have investigated factors that could be associated with seclusion. The aim of this study was to assess the clinical and socio-demographic characteristics of patients who were prescribed seclusion.

Patients and methods

An observational, retrospective study was carried out between January 2019 and December 2020, including patients with psychosis who had been hospitalized. Clinical and socio-demographic characteristics, as well as psychopathological scores were compared between patients who required seclusion and those who did not. A binomial logistic regression including gender, age, symptom severity, knowledge of the French language and judicial history was performed.

Results

We included 127 patients (41 of whom were prescribed seclusion). Patients requiring seclusion had more severe symptoms, as indicated by the Positive And Negative Syndrome Scale total scores (98.8 ± 21.95 vs 85.9 ± 25.64; P = 0.02), the positive symptoms subscale (28.4 ± 8.89 vs 24 ± 7.63; P = 0.02), and the general psychopathology symptoms subscale (48.3 ± 12.03 vs 41.9 ± 12.21; P = 0.02). These patients had poor knowledge of French (21% vs 4.7%; P < 0.01) and a statistical trend was found in relation to judicial history (24% vs 11%; P = 0.07). The differences in symptomatology (P = 0.03) and language knowledge (P = 0.04) were maintained in the multivariate analysis.

Discussion and conclusion

Our study found that the implementation of a seclusion was associated with the severity of symptoms and with a lack of knowledge of the French language. Particular attention should therefore be paid to these specific patients in order to use de-escalation techniques and provide comprehensible explanations to patients who do not speak French.
目的:隔离是精神病学中用于管理异性或自我攻击高危情况的最后手段。然而,很少有研究调查可能与隔离相关的因素。本研究的目的是评估处方隔离患者的临床和社会人口学特征。患者和方法:在2019年1月至2020年12月期间进行了一项观察性回顾性研究,包括住院的精神病患者。比较了需要隔离和不需要隔离的患者的临床和社会人口学特征以及精神病理学评分。二项逻辑回归包括性别、年龄、症状严重程度、法语知识和司法历史。结果:我们纳入了127例患者(其中41例接受了隔离治疗)。阳性和阴性综合征量表总分显示,需要隔离的患者症状更严重(98.8±21.95 vs 85.9±25.64;P=0.02),阳性症状量表(28.4±8.89 vs 24±7.63;P=0.02),一般精神病理症状量表(48.3±12.03 vs 41.9±12.21;P = 0.02)。这些患者法语知识贫乏(21% vs 4.7%;讨论和结论:我们的研究发现,隔离的实施与症状的严重程度和缺乏法语知识有关。因此,应特别注意这些特定的患者,以便使用降级技术并向不会说法语的患者提供可理解的解释。
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引用次数: 0
Sociodemographic and psychopathological profiles of criminal offenders following psychiatric assessment 精神病评估后刑事罪犯的社会人口学和精神病理学特征。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.01.013
Elise Finelle , Irène François-Purssell , Jean-Christophe Chauvet-Gelinier , Mélanie Loiseau

Aim of the study

Our aim was to identify the sociodemographic and psychopathological profiles of individuals undergoing criminal psychiatric assessment.

Materials and methods

This observational, descriptive, retrospective, monocentric study of criminal psychiatric assessments was performed in the Forensic Medicine Department of the Dijon Bourgogne University Hospital between January 1, 2019, and December 31, 2023.

Results

We included 235 criminal assessments, including 201 pre-sentence assessments. The offenders were mainly male (92.5%) with a median age of 37. According to the assessments, 63.7% of offenders suffered from psychiatric disorders, mostly psychotic. Half of the offenders had a criminal record and fewer than a third were repeat offenders (31.7%). The main offences were violence (20%), sexual offences against minors (12.8%) and robbery (10.4%). The assessments found that around two-thirds of the defendants suffered from psychiatric disorders, mainly psychotic disorders (45.3%), personality disorders (23.4%) and depressive disorders (8.6%). The expert noted impaired discernment in 44.4% of cases, and abolition in 13.6%. Finally, the expert warned of dangerousness in 69.6% of respondents, three-quarters of whom suffered from psychiatric disorders.

Conclusion

Our study enabled us to describe the typical profile offenders which could be used to implement prevention and targeted care.
研究目的:我们的目的是确定接受刑事精神病学评估的个人的社会人口学和精神病理学概况。材料和方法:这项观察性、描述性、回顾性、单中心的犯罪精神评估研究于2019年1月1日至2023年12月31日在第戎勃艮第大学医院法医学部进行。结果:共纳入235项刑事评估,其中201项为刑前评估。罪犯以男性为主(92.5%),中位年龄37岁。根据评估,63.7%的罪犯患有精神障碍,以精神病为主。一半的罪犯有犯罪记录,不到三分之一的人是惯犯(31.7%)。主要罪行是暴力(20%)、对未成年人进行性犯罪(12.8%)和抢劫(10.4%)。评估发现,大约三分之二的被告患有精神障碍,主要是精神障碍(45.3%)、人格障碍(23.4%)和抑郁症(8.6%)。该专家指出,44.4%的案例中有识别障碍,13.6%的案例中有废除。最后,专家警告说69.6%的受访者有危险,其中四分之三的人患有精神疾病。结论:本研究对典型的犯罪分子进行了描述,为实施预防和针对性护理提供了依据。
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引用次数: 0
Role of smoking status on motivation to reduce or stop alcohol consumption in patients with an alcohol use disorder admitted to an emergency department 在急诊科收治的酒精使用障碍患者中,吸烟状况对减少或停止饮酒动机的作用
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.01.009
Anna Mendy , Anne-Laurence Le Faou , Lisa Ferrand , Frédéric Limosin , Guillaume Airagnes
<div><h3>Objective</h3><div>To examine the role of smoking status on motivation to reduce alcohol consumption in patients admitted to the emergency department (ED) with alcohol use disorder (AUD).</div></div><div><h3>Methods</h3><div><span>A standardized questionnaire was administered to patients admitted to the ED of the Hôpital Européen Georges-Pompidou (Paris, France), whatever the cause of admission, as part of an AUD screening, brief intervention, and referral to treatment (SBIRT) program. The questionnaire collected demographic, cognitive impairment assessment variables including school curriculum difficulties and medical characteristics, smoking status, cannabis use and the Fast Alcohol Consumption Evaluation (FACE) for AUD risk assessment. Patients aged 18–90</span> <!-->years with a FACE score<!--> <!-->≥<!--> <!-->4 for women and<!--> <!-->≥<!--> <!-->5 for men were selected. An analogue scale from 0 to 10 was used to assess motivation, estimation of the right time, and self-confidence to reduce or stop alcohol consumption.</div></div><div><h3>Results</h3><div>Of the 3903 patients included between 2021 and 2023, 803 (21%) presented with TUA, with 72% excessive drinkers and 28% with a probable alcohol dependence. The study population was predominantly male (<em>n</em> <!-->=<!--> <!-->418, 52%). Current smokers accounted for 43% of patients (<em>n</em> <!-->=<!--> <!-->343), and only 8% (<em>n</em> <!-->=<!--> <!-->27) wished to obtain the contact details of the national quitline Tabac-Info-Service, a percentage twice as high as that observed among smokers at low or no risk of AUD. The average age was 48.7<!--> <!-->years (SD: 21.6), and smokers had a lower average age than the average for all participants (41<!--> <!-->years, SD: 17.4). On the other hand, former smokers were older on average (58.3<!--> <!-->years, SD: 20.6). In all, 36% (<em>n</em> <!-->=<!--> <!-->209) of patients with excessive alcohol consumption were smokers while 59% (<em>n</em> <!-->=<!--> <!-->134) of those with probable alcohol dependence were smokers. In terms of school curriculum, 13% (<em>n</em> <!-->=<!--> <!-->108) had experienced learning difficulties (50% of whom were smokers), 42% (<em>n</em> <!-->=<!--> <!-->339) had repeated a year (44% of whom were smokers), and 18% (<em>n</em> <!-->=<!--> <!-->146) had been suspended or excluded from school (53% of whom were smokers). In terms of neurological history, 35% (<em>n</em> <!-->=<!--> <!-->278) had suffered from memory loss and 19% (<em>n</em> <!-->=<!--> <!-->156) from fainting (42%, 53% of whom were smokers respectively). Less than 10% reported epilepsy episodes (8.7%: <em>n</em> <!-->=<!--> <!-->70) or neurodevelopmental disorders (6.4%: <em>n</em> <!-->=<!--> <!-->51). Among them, 54% and 61% respectively were smokers. Past-month cannabis use concerned 14% of patients (<em>n</em> <!-->=<!--> <!-->112), 85% of whom declared they smoked. In the descriptive analyses, more smokers than non-smokers felt tha
目的:探讨吸烟状况对急诊科(ED)酒精使用障碍(AUD)患者减少饮酒动机的影响。方法:对Hôpital europ -乔治-蓬皮杜(巴黎,法国)急诊收治的患者进行标准化问卷调查,无论入院原因是什么,作为AUD筛查、短暂干预和转诊治疗(SBIRT)计划的一部分。问卷收集了人口学、认知障碍评估变量,包括学校课程困难和医学特征、吸烟状况、大麻使用和快速酒精消费评估(FACE),用于AUD风险评估。患者年龄为18-90岁,女性FACE评分≥4,男性≥5。使用从0到10的模拟量表来评估减少或停止饮酒的动机、对正确时间的估计和自信。结果:在2021年至2023年期间纳入的3903例患者中,803例(21%)出现TUA,其中72%过度饮酒者,28%可能有酒精依赖。研究人群以男性为主(n=418, 52%)。目前吸烟者占患者的43% (n=343),只有8% (n=27)希望获得国家戒烟热线烟草信息服务的联系方式,这一比例是低AUD风险或无AUD风险吸烟者的两倍。平均年龄为48.7岁(SD: 21.6),吸烟者的平均年龄低于所有参与者的平均年龄(41岁,SD: 17.4)。另一方面,戒烟者的平均年龄更大(58.3岁,SD: 20.6)。总的来说,36% (n=209)的过度饮酒患者是吸烟者,而59% (n=134)的可能酒精依赖患者是吸烟者。在学校课程方面,13% (n=108)经历过学习困难(其中50%是吸烟者),42% (n=339)重复一年(其中44%是吸烟者),18% (n=146)被停学或开除(其中53%是吸烟者)。在神经学史方面,35% (n=278)患有记忆丧失,19% (n=156)患有昏厥(其中42%和53%分别为吸烟者)。不到10%的人报告癫痫发作(8.7%:n=70)或神经发育障碍(6.4%:n=51)。其中,吸烟者占54%,吸烟者占61%。过去一个月使用大麻的患者占14% (n=112),其中85%的人声称他们吸烟。在描述性分析中,吸烟者比非吸烟者更多地认为,他们进入ED促使他们减少或停止饮酒,认为这是正确的时机,并宣称在实现这一目标方面有更高的信心。在双变量分析中,动机和减少或停止饮酒的正确时间与吸烟者显著相关,但这些结果在多变量分析中没有发现。结论:这些结果表明,在急诊科筛查出AUD的患者中,吸烟状况不会干预因AUD风险而接受SBI后改变饮酒行为的动机。这些结果支持这样一种观点,即戒烟建议可以系统化地适用于所有急诊科患者,而不会影响他们减少或停止饮酒的动机。
{"title":"Role of smoking status on motivation to reduce or stop alcohol consumption in patients with an alcohol use disorder admitted to an emergency department","authors":"Anna Mendy ,&nbsp;Anne-Laurence Le Faou ,&nbsp;Lisa Ferrand ,&nbsp;Frédéric Limosin ,&nbsp;Guillaume Airagnes","doi":"10.1016/j.encep.2025.01.009","DOIUrl":"10.1016/j.encep.2025.01.009","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To examine the role of smoking status on motivation to reduce alcohol consumption in patients admitted to the emergency department (ED) with alcohol use disorder (AUD).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;&lt;span&gt;A standardized questionnaire was administered to patients admitted to the ED of the Hôpital Européen Georges-Pompidou (Paris, France), whatever the cause of admission, as part of an AUD screening, brief intervention, and referral to treatment (SBIRT) program. The questionnaire collected demographic, cognitive impairment assessment variables including school curriculum difficulties and medical characteristics, smoking status, cannabis use and the Fast Alcohol Consumption Evaluation (FACE) for AUD risk assessment. Patients aged 18–90&lt;/span&gt; &lt;!--&gt;years with a FACE score&lt;!--&gt; &lt;!--&gt;≥&lt;!--&gt; &lt;!--&gt;4 for women and&lt;!--&gt; &lt;!--&gt;≥&lt;!--&gt; &lt;!--&gt;5 for men were selected. An analogue scale from 0 to 10 was used to assess motivation, estimation of the right time, and self-confidence to reduce or stop alcohol consumption.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Of the 3903 patients included between 2021 and 2023, 803 (21%) presented with TUA, with 72% excessive drinkers and 28% with a probable alcohol dependence. The study population was predominantly male (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;418, 52%). Current smokers accounted for 43% of patients (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;343), and only 8% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;27) wished to obtain the contact details of the national quitline Tabac-Info-Service, a percentage twice as high as that observed among smokers at low or no risk of AUD. The average age was 48.7&lt;!--&gt; &lt;!--&gt;years (SD: 21.6), and smokers had a lower average age than the average for all participants (41&lt;!--&gt; &lt;!--&gt;years, SD: 17.4). On the other hand, former smokers were older on average (58.3&lt;!--&gt; &lt;!--&gt;years, SD: 20.6). In all, 36% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;209) of patients with excessive alcohol consumption were smokers while 59% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;134) of those with probable alcohol dependence were smokers. In terms of school curriculum, 13% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;108) had experienced learning difficulties (50% of whom were smokers), 42% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;339) had repeated a year (44% of whom were smokers), and 18% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;146) had been suspended or excluded from school (53% of whom were smokers). In terms of neurological history, 35% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;278) had suffered from memory loss and 19% (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;156) from fainting (42%, 53% of whom were smokers respectively). Less than 10% reported epilepsy episodes (8.7%: &lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;70) or neurodevelopmental disorders (6.4%: &lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;51). Among them, 54% and 61% respectively were smokers. Past-month cannabis use concerned 14% of patients (&lt;em&gt;n&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;112), 85% of whom declared they smoked. In the descriptive analyses, more smokers than non-smokers felt tha","PeriodicalId":51042,"journal":{"name":"Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique","volume":"52 1","pages":"Pages 11-18"},"PeriodicalIF":1.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Representations and knowledge of residents about ADHD in children in two regions in France 法国两个地区居民对儿童ADHD的认知和陈述。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.02.002
Thiébaut-Noël Willig , Louise Brun , Anne Piollet , Marie Dajon , Marie-Claire Thiollier , Rémy Assathiany , Pierre Fourneret , Stéphane Oustric , Michel Amouyal , Magali Masse , Anne Monge , Diane Purper Ouakil

Introduction

In France, knowledge and awareness of childhood ADHD remain insufficient. To guide the development of training programs for medical residents, we assessed the understanding of ADHD among residents in family practice, pediatrics, and psychiatry across two major French regions in 2021.

Methods

A SurveyMonkey® survey was distributed to residents in two French regions, gathering information about their training experiences on child/adolescent ADHD, as well as their knowledge and perceptions of the disorder.

Results

Among the 251 residents who completed the survey (response rate: 28.5%), 53.4% reported receiving no training on ADHD during their residency. Substantial differences were observed across specialties: 75% of psychiatry residents reported receiving training, compared to only 38% of family practice residents. Even brief training sessions (e.g., one hour) significantly improved knowledge and perceptions of ADHD, with greater effectiveness observed as the duration of training increased.

Conclusions

Residency training on ADHD shows potential for improving access to care as post-training knowledge and perceptions align with those of trained practitioners actively managing ADHD in the same regions. Action plans are recommended to enhance training for family practice residents, with follow-up assessments planned using the same methodology.
在法国,儿童多动症的知识和意识仍然不足。为了指导住院医师培训计划的发展,我们评估了2021年法国两个主要地区家庭执业、儿科和精神病学住院医师对ADHD的理解。方法:通过SurveyMonkey®对法国两个地区的居民进行调查,收集他们关于儿童/青少年ADHD培训经历的信息,以及他们对该疾病的认识和认知。结果:在完成调查的251名住院医师中(回复率:28.5%),53.4%的住院医师报告在住院期间未接受过ADHD培训。在不同的专业中观察到实质性的差异:75%的精神科住院医生报告接受过培训,而家庭执业住院医生只有38%。即使是短暂的训练(例如一小时)也能显著提高对多动症的认识和认知,随着训练时间的延长,效果也会越来越好。结论:关于ADHD的住院医师培训显示了改善获得护理的潜力,因为培训后的知识和观念与同一地区训练有素的从业人员积极管理ADHD的知识和观念一致。建议采取行动计划,加强对家庭执业住院医师的培训,并计划使用相同的方法进行后续评估。
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引用次数: 0
An education tool on clozapin: From needs assessment to patient satisfaction 氯氮平教育工具:从需求评估到患者满意度。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.03.003
Céline Straczek , Alba Lopez-Krahe , Ahava Cohen , Emilie Cohen , Eimma Calimouttoupoulle , Bénédicte Louvet , Muriel Paul , Baptiste Pignon , Murielle Pecal Dalle
Clozapine remains the gold-standard for resistant schizophrenia. However, it is associated with serious adverse events and a low patient adherence that could be enhanced by therapeutic education. Identifying patients’ needs is a prerequisite for building educational tools. The aims of the study were to build an adapted information tool after evaluating patients’ knowledge and expectations regarding their clozapine treatment, and to estimate patients’ satisfaction with this tool. Patients’ knowledge and expectations were evaluated by means of a short oral and semi-structured interview, based on an 11-item questionnaire developed by pharmacists and psychiatrists. Patients with schizophrenia or a schizo-affective disorder were included from four different care structures of the university psychiatry department. Finally, an education tool was built based on patients’ answers and tested among them. Between February 2020 and September 2021, 51 patients (17 women) around 36 years of age were interviewed. 45% were aware of a clozapine indication. Half of the patients did not know how to react in case of forgetting a dose. Although the rhythm of blood tests was understood by most patients (84%), only 29% estimated they had a general knowledge about them. Many patients (73%) could cite no more than two adverse effects. Regarding interactions, 69% had a partial knowledge and 31% none at all. Patients preferred to receive information in the form of a brochure. The subsequent brochure was tested on 15 patients who were satisfied with it. The survey revealed a general lack of knowledge among patients about their clozapine treatment. The tool built based on patients’ answers has been adapted and liked by patients.
氯氮平仍然是治疗难治性精神分裂症的金标准。然而,它与严重的不良事件和低患者依从性相关,这可以通过治疗教育来增强。确定患者的需求是建立教育工具的先决条件。本研究的目的是在评估患者对氯氮平治疗的知识和期望后,建立一个适应的信息工具,并估计患者对该工具的满意度。患者的知识和期望通过简短的口头和半结构化访谈来评估,基于药剂师和精神科医生开发的11项问卷。患有精神分裂症或精神分裂情感障碍的患者来自大学精神科的四个不同的护理结构。最后,根据患者的回答构建教育工具,并在患者中进行测试。在2020年2月至2021年9月期间,对51名36岁左右的患者(17名女性)进行了采访。45%的患者知道氯氮平的适应症。一半的患者不知道如果忘记服药该如何反应。尽管大多数患者(84%)了解血液检查的节奏,但只有29%的患者估计他们对此有一般的了解。许多患者(73%)能举出不超过两种不良反应。在互动方面,69%的人有部分知识,31%的人完全不知道。患者更喜欢以小册子的形式接收信息。随后的小册子在15名满意的患者身上进行了测试。调查显示,患者普遍缺乏氯氮平治疗方面的知识。该工具是根据患者的回答建立的,并受到患者的喜爱。
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引用次数: 0
Peer-support and group psychoeducation for patients with borderline personality disorder: A feasibility study 边缘型人格障碍患者同伴支持与团体心理教育的可行性研究。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.01.012
Martin Blay , Arjin Uludag-Martin , Saioa Lagadec , Marion Zenou , Inès Benmakhlouf

Objective

Borderline personality disorder (BPD) is a common disorder associated with poor mental health and socio-professional outcomes. Even though it is known to be a treatable condition, almost half of the patients are still not responding to current psychotherapeutic treatment programs. Peer-support interventions are thought to be an interesting way to improve these treatments, but data regarding the feasibility of such interventions are scarce.

Methods

The present naturalistic study aimed to assess the feasibility and acceptability of incorporating a peer-support worker (PSW) with a lived experience of BPD as a co-leader in an evidence-based psychoeducation group based on Good Psychiatric Management for patients with BPD, with a pre-post design.

Results

Overall, 46 patients were included in the analysis, among whom 34 completed the post-group analysis. Almost all the patients found the presence of the PSW relevant and useful, completion rates were high, and security outcomes were satisfactory.

Conclusion

Despite numerous limitations, including the naturalistic design, the absence of a control group, and the high level of training of our PSW (that limits the generalizability of our findings to less trained PSW), we believe that our study adds to the current scarce literature on the usefulness of integrating PSW with a lived experience of BPD in evidence-based treatment programs for patients with BPD.
目的:边缘型人格障碍(BPD)是一种与不良心理健康和社会职业结果相关的常见障碍。尽管已知这是一种可治疗的疾病,但几乎一半的患者仍然对目前的心理治疗方案没有反应。同伴支持干预被认为是改善这些治疗的一种有趣的方式,但关于这种干预的可行性的数据很少。方法:本自然主义研究旨在评估一名有BPD生活经验的同伴支持工作者(PSW)作为基于BPD患者良好精神管理的循证心理教育小组共同领导的可行性和可接受性,采用前后设计。结果:共纳入46例患者,其中34例完成组后分析。几乎所有患者都认为PSW的存在是相关和有用的,完成率高,安全性结果令人满意。结论:尽管存在许多局限性,包括自然设计,缺乏对照组,以及我们的PSW的高水平训练(这限制了我们的研究结果在训练较少的PSW中的推广),我们相信我们的研究增加了目前稀缺的文献,即将PSW与BPD的生活经验结合起来,在BPD患者的循证治疗方案中是有用的。
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引用次数: 0
French validation of the POCS scale: A tool for screening intrusive thoughts, obsessions, and compulsions during pregnancy and postpartum POCS量表的法国验证:一种筛查怀孕和产后侵入性思想、强迫和强迫的工具。
IF 1 4区 医学 Q4 NEUROSCIENCES Pub Date : 2026-02-01 DOI: 10.1016/j.encep.2025.04.002
Catherine Lord , Marie-Luce Faure , Wissam El-Hage , Laurence Joly , Benoît Bayle

Objectives

This study addressed the growing recognition of mental health disorders during the perinatal period, in particular obsessive-compulsive disorder (OCD). OCD symptoms can affect between 3% and 10% of women during the perinatal period, a higher prevalence than in the general population. The Perinatal Obsessive-Compulsive Scale (POCS), developed in Canada, is to our knowledge the only validated tool for screening OCD in the perinatal context. This study aimed to validate the French version of the POCS in order to improve early detection of OCD symptoms among French-speaking mothers and fathers.

Methods

The study included 227 pregnant women in their third trimester and 113 in the early postpartum period. The POCS was translated into French using the forward and backward translation method, in collaboration with bilingual experts from France and Quebec. Other measures included validated tools: the Obsessional Compulsive Inventory–Revised (OCI-R) for general OCD and the Edinburgh Postnatal Depression Scale (EPDS) for depressive symptoms. Data were collected in person and online during the COVID-19 pandemic. Statistical analyses included descriptive statistics, reliability tests (Cronbach's alpha), and ROC curve analysis to assess the validity and discriminative capacity of the scale.

Results

The French version of the POCS showed strong internal consistency and psychometric properties similar to the English version. The POCS had good convergent validity, correlating with the OCI-R and showing a distinct link to depression symptoms via the EPDS. Exploratory analysis demonstrated that a high proportion of that perinatal sample reported OCD symptoms.

Conclusions

The French version of the POCS is reliable and valid for screening OCD symptoms in women during the perinatal period. The study highlights the need for screening tools specific to this population The POCS is a valuable clinical tool for early identification and intervention regarding perinatal OCD symptoms. Its systematic use in maternal health services could enhance mental health support for mothers during pregnancy and postpartum.
目的:本研究旨在解决围产期心理健康障碍,特别是强迫症(OCD)日益增加的认识。在围产期,强迫症症状可影响3%至10%的妇女,患病率高于一般人群。围产期强迫症量表(POCS)是加拿大开发的,据我们所知,这是围产期筛查强迫症的唯一有效工具。本研究旨在验证法语版本的POCS,以提高法语父母对强迫症症状的早期发现。方法:研究对象为227例妊娠晚期孕妇和113例产后早期孕妇。在法国和魁北克省双语专家的合作下,使用正反译法将《POCS》翻译成法语。其他测量包括验证工具:强迫性强迫症的强迫症清单修订版(OCI-R)和抑郁症状的爱丁堡产后抑郁量表(EPDS)。在COVID-19大流行期间,亲自和在线收集了数据。统计分析采用描述性统计、信度检验(Cronbach’s alpha)和ROC曲线分析来评估量表的效度和判别能力。结果:法语版POCS具有较强的内部一致性和与英语版相似的心理测量特性。POCS具有良好的收敛效度,与OCI-R相关,并通过EPDS显示出与抑郁症状的明显联系。探索性分析表明,围产期样本中报告强迫症症状的比例很高。结论:法语版POCS在围产期筛查女性强迫症症状方面是可靠和有效的。该研究强调需要针对这一人群的筛查工具,POCS是早期识别和干预围产期强迫症症状的有价值的临床工具。在孕产妇保健服务中系统地使用它可以加强对怀孕期间和产后母亲的心理健康支持。
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引用次数: 0
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Encephale-Revue De Psychiatrie Clinique Biologique et Therapeutique
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