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[Complementary, alternative and integrative therapies in medical guidelines - the guideline "Diagnosis and treatment of ulcerative colitis" as an example of successful integration]. [医学指南中的补充、替代和综合疗法——指南"溃疡性结肠炎的诊断和治疗"作为成功综合的一个例子]。
Pub Date : 2014-01-01 Epub Date: 2014-02-17 DOI: 10.1159/000358577
Holger Cramer, Romy Lauche, Petra Klose, Gustav Dobos, Jost Langhorst
Die aktuelle Leitlinie «Diagnostik und Therapie der Colitis ulcerosa» wurde im September 2011 unter Federfuhrung der Deutschen Gesellschaft fur Verdauungsund Stoffwechselkrankheiten (DGVS) und Mitarbeit der Deutschen Gesellschaft fur Pathologie (DGP), der Deutschen Gesellschaft fur Allgemeinund Viszeralchirurgie (DGVC), der Gesellschaft fur padiatrische Gastroenterologie und Ernahrung (GPGE) sowie der Deutschen Gesellschaft fur Ernahrungsmedizin (DGEM) vorgelegt. Die nachste Aktualisierung ist fur September 2016 avisiert; die gegebenen Empfehlungen werden also noch eine geraume Weile den Goldstandard in der Therapie der Colitis ulcerosa darstellen [1]. Fur eine Reihe komplementarmedizinischer Verfahren enthielt die Leitlinie evidenzbasierte positive Empfehlungen, die einen hinreichenden Konsens in der Leitlinienkonferenz fanden (Tab. 1). So wurden abgeschwacht positive Empfehlungen fur das Phytotherapeutikum Plantago ovata gegeben, das sich in einer klinischen Studie Mesalazin in der remissionserhaltenden Behandlung als ebenburtig erwies (Empfehlung 10.16); ebenso fur Curcumin, das in der remissionserhaltenden Behandlung komplementar zu 5-ASA empfohlen wird (Empfehlung 10.15). Ein Problem in der Anwendung von Curcumin in Deutschland ergibt sich allerdings daraus, dass in der japanischen Studie [2], auf der die Empfehlung beruht, Curcumin in einer Dosis von 2 × 1 g/Tag eingesetzt wurde, wahrend die in Deutschland verfugbaren Praparate deutlich geringere Dosierungen enthalten. Daneben gibt die Leitlinie eine abgeschwacht positive Empfehlung fur Akupunktur in Kombination mit Moxibustion als komplementare Therapie im leichten bis moderaten Schub (Empfehlung 10.18) sowie fur eine multimodale komplementare Mind-Body-Therapie zur Verbesserung der Lebensqualitat (Empfehlung 10.17). Letztere Empfehlung ist bisher nahezu einzigartig in Deutschland; erstmals wird hier eine multimodale MindBody-Therapie empfohlen, wie sie in Deutschland in integrativmedizinischen Kliniken angeboten wird [3]. Die Empfehlung basiert unter anderem auf einer deutschen randomisierten Studie [4, 5], die zeigen konnte, dass ein multimodales Lebensstilmodifikationsprogramm mit Elementen der Mind-Body-Medizin die Lebensqualitat von Patienten in Remission oder mit geringer Krankheitsaktivitat in klinisch relevantem Umfang steigern kann. Weitere komplementarmedizinische Verfahren, inklusive weiterer Phytotherapeutika und einzelner Verfahren der Mind-Body-Medizin wie Yoga oder Qigong, konnten aufgrund der unzureichenden Datenlage nicht empfohlen werden (Empfehlung 10.20). Ein potenzieller Kandidat fur zukunftige Aktualisierungen der Leitlinie scheint die Behandlung mit Eiern des Schweinepeitschenbandwurms (Trichuris suis ovata) zu sein, die in einer randomisierten Studie im leichten bis moderaten Schub die Krankheitsaktivitat signifikant starker senken konnte als Placebo, derzeit aber – vor dem Hintergrund der fehlenden Zulassung in Deutschland – nicht generell empfohlen wird (Empfehlun
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引用次数: 4
Stress-relieving effects of short-term balneotherapy - a randomized controlled pilot study in healthy adults. 短期按摩疗法的减压效果——一项健康成人随机对照试验研究
Pub Date : 2014-01-01 Epub Date: 2014-03-17 DOI: 10.1159/000360966
Franziska Matzer, Eva Nagele, Babak Bahadori, Karl Dam, Christian Fazekas

Background: Stress-relieving effects of balneotherapy compared to progressive muscle relaxation (PMR) and to resting were investigated by measuring subjective relaxation and salivary cortisol. It was also examined whether participants with a high versus low stress level would have a different relaxation response.

Methods: A sample of healthy volunteers was randomized to balneotherapy, PMR, or a resting control group, each intervention lasting for 25 min. Pre- and post-intervention salivary cortisol samples were collected, and participants rated their status of relaxation on a quantitative scale. In addition, 3 questionnaires were applied to detect participants' stress level and bodily complaints.

Results: 49 healthy participants were recruited (65.3% female). In a pre-post comparison, salivary cortisol decreased (F = 23.53, p < 0.001) and subjective relaxation ratings increased (F = 132.18, p < 0.001) in all 3 groups. Study participants in the balneotherapy group rated themselves as more relaxed after the intervention as compared to the other groups (F = 5.22, p < 0.009). Participants with a high versus low stress level differed in somatic symptoms and in morning cortisol levels, but showed a similar relaxation response.

Conclusion: Findings suggest that compared to PMR and resting, balneotherapy seems to be more beneficial with regard to subjective relaxation effects and similarly beneficial with regard to a decrease in salivary cortisol.

背景:通过测量主观放松和唾液皮质醇,研究了按摩疗法与渐进式肌肉放松(PMR)和休息相比较的压力缓解效果。研究人员还检查了高压力水平和低压力水平的参与者是否会有不同的放松反应。方法:将健康志愿者随机分为沐浴疗法组、PMR组和静息对照组,每次干预持续25分钟。收集干预前和干预后唾液皮质醇样本,参与者以定量量表评估他们的放松状态。此外,还使用3份问卷来检测参与者的压力水平和身体抱怨。结果:49名健康受试者被招募,其中65.3%为女性。在前后比较中,三组唾液皮质醇降低(F = 23.53, p < 0.001),主观放松评分升高(F = 132.18, p < 0.001)。与其他组相比,沐浴疗法组的研究参与者在干预后认为自己更放松(F = 5.22, p < 0.009)。高压力水平和低压力水平的参与者在躯体症状和早晨皮质醇水平上有所不同,但表现出相似的放松反应。结论:研究结果表明,与PMR和休息相比,浴疗似乎在主观放松效果方面更有益,在降低唾液皮质醇方面也同样有益。
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引用次数: 9
[Efficacy in phytotherapy]. [植物疗法的功效]。
Pub Date : 2014-01-01 Epub Date: 2014-07-04 DOI: 10.1159/000362394
Reinhard Saller, Jörg Melzer, Günter Meng, Ursula von Mandach, Karin Fürer, Herbert Schwabl, Cecile Vennos
ePerinatale Pharmakologie, UniversitatsSpital Zurich, f Padma AG, Hinwil, Schweiz Die moderne Phytotherapie ist im Rahmen ihrer materiellen Moglichkeiten ein durchaus forschungsaffiner Therapiebereich. Neben einem mehrdimensionalen Ansatz, anhand einer Heilpflanze beispielhaft ein potentiel les phytotherapeutisches Therapiespektrum auszuloten geht es vor allem um eine reflektierte wissenschaftliche Auseinandersetzung mit Methodologie, Aussagekraft und notwendigen Modifizierungen von Metaanalysen sowie mit Ansatzen aus der Versorgungsforschung. Beide Vorgehensweisen bilden derzeit auch in der Phytotherapie einen viel beachteten Fokus der klinischen und klinisch-epidemiologischen Forschung. Die Metaanalysen beschaftigen sich naturgemas mit bereits vorhandenen Studiendaten und treffen dabei jeweils eine begrundete wenngleich selektive und forscherbezogen durchaus subjektive Auswahl. Spezifische phytothera peutische Gesichtspunkte wie z.B. Besonderheiten von Extrakten oder Vergleichbarkeit von Phytotherapeutika werden bislang kaum wissenschaftlich angemessen berucksichtigt. In der Versorgungsforschung, die nicht durch fixe Studienvorgaben eingeschrankt ist, stehen Daten aus der flexiblen und variablen Praxis im Vorder grund. Dieser Ansatz kann es, bei allen Einschrankungen, ermoglichen, neue und therapierelevante Gesichtspunkte zu entdecken, z.B. im Hinblick auf Dosierungen. Der authentische Charakter von Phytotherapeutika als Vielstoffgemische in stofflicher und funktioneller Hin sicht mit genuinen pleiotropen Eigenschaften wird bislang in der Forschung, vor allem der pharmakologischen Forschung, nur selten adaquat aufgegriffen. Vergleichbar werden pflanzliche Arzneimittel noch im mer praferentiell unter dem eher realitatsfernen Grundsatz gesehen: «one drug, one indication». Die Betrachtung und Beforschung von Phytotherapeutika als Netzwerkarzneimittel mit pleiotropen Signaturen weist auf zukunfstrachtige Vorgehensweisen hin.
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引用次数: 5
Clinical effects of needle-pricking therapy on peripheral facial paralysis. 针刺疗法治疗周围性面瘫的临床疗效。
Pub Date : 2014-01-01 Epub Date: 2014-02-17 DOI: 10.1159/000358742
You-Jung Kwon, Seunghoon Lee, Sangmin Park, Ungin Lee, Sung-Keun Lim, Dongwoo Nam, Sanghoon Lee

Background: The aim of this study was to investigate the effects of needle-pricking therapy on peripheral facial paralysis.

Methods: This study included 162 patients with peripheral facial paralysis, 107 of whom were treated with usual care (conventional and alternative treatments) and 55 of whom were additionally treated with needle-pricking therapy on 3 specific extra-meridian acupuncture points known as 'Samjoong' (Sānchóng in Chinese). We evaluated changes in facial motor functions and sequelae using the Yanagihara and gross House-Brackmann grading systems before and after treatments.

Results: Yanagihara score and House-Brackmann grade significantly improved after treatments in both groups. However, the needle-pricking therapy group showed greater improvements in Yanagihara score and House-Brackmann grade than the usual care group.

Conclusion: Our results suggest that Samjoong needle-pricking therapy could be applied as an adjunct therapy to usual care for patients with peripheral facial paralysis.

背景:本研究的目的是探讨针刺治疗周围性面瘫的效果。方法:本研究纳入162例周围性面瘫患者,其中107例采用常规治疗(常规和替代治疗),55例在经外3个特定穴位“三中”(Sānchóng)进行针刺治疗。我们使用Yanagihara和gross House-Brackmann评分系统评估治疗前后面部运动功能和后遗症的变化。结果:治疗后两组患者的Yanagihara评分和House-Brackmann评分均显著提高。然而,针刺治疗组在Yanagihara评分和House-Brackmann评分方面比常规治疗组有更大的改善。结论:三重针疗法可作为周围性面瘫患者日常护理的辅助疗法。
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引用次数: 4
[Interpersonal attention management inventory: a new instrument to capture different self- and external perception skills]. 人际注意管理量表:一种捕捉不同自我和外部感知技能的新工具。
Pub Date : 2014-01-01 Epub Date: 2014-02-18 DOI: 10.1159/000358176
Klaus Blaser, Milena Zlabinger, Thilo Hinterberger

Background: The Interpersonal Attention Management Inventory (IAMI) represents a new instrument to capture self- and external perception skills. The underlying theoretical model assumes 3 mental locations of attention (the intrapersonal space, the extrapersonal space, and the external intrapersonal space) of the other.

Methods: The IAMI was studied regarding its factor structure; it was shortened and statistical values as well as first reference values were calculated based on a larger sample (n = 1089).

Results: By factor analysis, the superordinate scales could be widely validated. The shortened version with 31 items and 3 superordinate scales shows a high reliability of the global value (Cronbach's α = 0.81) and, regarding the convergent validity, a modest correlation (r = 0.41) of the global value and mindfulness, measured with the Freiburg Mindfulness Inventory (FMI).

Conclusions: Further validation studies are invited so that the IAMI can be used as an instrument for (course) diagnosis in the therapy of psychiatric disorders as well as for research in social neuroscience, e.g., in investigations on mindfulness, compassion, empathy, theory of mind, and self-boundaries.

背景:人际注意管理量表(IAMI)是一种捕捉自我和外部感知技能的新工具。基础理论模型假设了他人的3个注意力心理位置(个人内部空间、个人外部空间和外部个人内部空间)。方法:对IAMI的因子结构进行研究;缩短时间,根据较大样本(n = 1089)计算统计值和第一参考值。结果:经因子分析,上位量表可广泛验证。由31个项目和3个上量表组成的精简版本显示,整体价值具有较高的信度(Cronbach's α = 0.81),而在收敛效度方面,Freiburg正念量表(FMI)测量的整体价值与正念之间存在适度的相关性(r = 0.41)。结论:需要进一步的验证性研究,以便IAMI可以用作精神疾病治疗(课程)诊断的工具,以及社会神经科学的研究,例如,正念,同情,移情,心理理论和自我界限的调查。
{"title":"[Interpersonal attention management inventory: a new instrument to capture different self- and external perception skills].","authors":"Klaus Blaser,&nbsp;Milena Zlabinger,&nbsp;Thilo Hinterberger","doi":"10.1159/000358176","DOIUrl":"https://doi.org/10.1159/000358176","url":null,"abstract":"<p><strong>Background: </strong>The Interpersonal Attention Management Inventory (IAMI) represents a new instrument to capture self- and external perception skills. The underlying theoretical model assumes 3 mental locations of attention (the intrapersonal space, the extrapersonal space, and the external intrapersonal space) of the other.</p><p><strong>Methods: </strong>The IAMI was studied regarding its factor structure; it was shortened and statistical values as well as first reference values were calculated based on a larger sample (n = 1089).</p><p><strong>Results: </strong>By factor analysis, the superordinate scales could be widely validated. The shortened version with 31 items and 3 superordinate scales shows a high reliability of the global value (Cronbach's α = 0.81) and, regarding the convergent validity, a modest correlation (r = 0.41) of the global value and mindfulness, measured with the Freiburg Mindfulness Inventory (FMI).</p><p><strong>Conclusions: </strong>Further validation studies are invited so that the IAMI can be used as an instrument for (course) diagnosis in the therapy of psychiatric disorders as well as for research in social neuroscience, e.g., in investigations on mindfulness, compassion, empathy, theory of mind, and self-boundaries.</p>","PeriodicalId":51049,"journal":{"name":"Forschende Komplementarmedizin","volume":"21 1","pages":"34-41"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000358176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40288679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The vitamins B₆, B₁₂ and folic acid - successful strategy for increasing vitality?]. [维生素B₆、维生素B₁2和叶酸——增加活力的成功策略?]
Pub Date : 2014-01-01
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引用次数: 0
An open-label pilot study of homeopathic treatment of attention deficit hyperactivity disorder in children and youth. 儿童和青少年注意缺陷多动障碍的顺势疗法治疗的开放标签试点研究。
Pub Date : 2014-01-01 Epub Date: 2014-09-19 DOI: 10.1159/000368137
David Brulé, Lauren Sule, Beth Landau-Halpern, Violeta Nastase, Umesh Jain, Sunita Vohra, Heather Boon

Background: An open-label pilot study of individualized homeopathy for attention deficit hyperactivity disorder (ADHD) was conducted to assess the potential for future studies with a focus on the feasibility of the recruitment plan and outcome measure schedules; identification of any group characteristics of participants who respond significantly to the therapy; and establishing the length of time required for an improvement in ADHD symptoms.

Patients and methods: Participants (aged 6-16) were recruited through community advertisement and outreach. Participants completed 1 screening and 9 individualized homeopathic follow-up consultations. ADHD symptoms were assessed using the Conners 3 - Parent Questionnaire administered at each consultation. The pre- and post-study difference in Conners Global Index - Parent (CGI-P) T-score was evaluated for each participant. Baseline data of those who showed a statistically significant improvement (responders) were compared to those who did not (non-responders).

Results: 35 participants were enrolled over 11 months. 80% completed all 10 consultations in a median of 12.1 months. 63% had a statistically significant improvement in the primary outcome, first occurring after a mean of 4.5 visits. Overall scores for participants completing at least 2 data points decreased from a baseline median of 85.5 to 74.0 (p < 0.001, CI 95%). There were no significant baseline differences between responders and non-responders. No serious adverse events related to the therapy were reported.

Conclusion: The change in the median CGI-P T-score from baseline to the end of this open-label pilot study was statistically significant. The research methods are feasible. Future studies are warranted.

Trial registration: NCT01141634.

背景:进行了一项针对注意缺陷多动障碍(ADHD)的个体化顺势疗法的开放标签试点研究,以评估未来研究的潜力,重点关注招募计划和结果测量时间表的可行性;确定对治疗有显著反应的参与者的任何群体特征;并确定改善ADHD症状所需的时间长度。患者和方法:通过社区广告和外展招募参与者(6-16岁)。参与者完成了1次筛查和9次个体化顺势疗法随访咨询。ADHD症状在每次咨询时使用Conners 3 - Parent Questionnaire进行评估。评估每个参与者的Conners Global Index - Parent (CGI-P) T-score在研究前和研究后的差异。基线数据显示有统计学显著改善的患者(应答者)与无应答者(无应答者)进行比较。结果:35名参与者在11个月的时间里被纳入研究。80%的患者在12.1个月的中位数时间内完成了所有10次咨询。63%的患者在主要结果上有统计学意义上的显著改善,首次出现在平均4.5次就诊后。完成至少2个数据点的参与者的总得分从基线中位数85.5下降到74.0 (p < 0.001, CI 95%)。在应答者和无应答者之间没有显著的基线差异。未见与治疗相关的严重不良事件的报道。结论:从基线到这项开放标签先导研究结束时,中位CGI-P t评分的变化具有统计学意义。研究方法是可行的。未来的研究是有必要的。试验注册:NCT01141634。
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引用次数: 7
Treatment of organic livestock with medicinal plants: a systematic review of European ethnoveterinary research. 用药用植物治疗有机牲畜:欧洲民族兽医研究的系统回顾。
Pub Date : 2014-01-01 Epub Date: 2014-12-12 DOI: 10.1159/000370216
Maria Mayer, Christian R Vogl, Michele Amorena, Matthias Hamburger, Michael Walkenhorst

Background: The EC Regulation for Organic Farming states that organic livestock should be treated preferably with phytotherapeutic products. In spite of the high importance of organic livestock in Europe, primarily ruminants, today almost no phytotherapeutic product is registered for livestock. Also, information regarding veterinary phytotherapy is rare. The aim of this paper is to find approaches to cope with health problems of organic ruminants in Europe on the basis of findings from the European ethnoveterinary medicine (EuEVM).

Methods: A systematic review of ethno-biomedicinal papers was conducted with the aid of the Scopus database, and 75 papers, from European countries were analyzed regarding ethnoveterinary information.

Results: A total of 590 plant species referring to 102 different plant families are reported to be used for animal treatment, with Asteraceae, Fabaceae and Lamiaceae being the most important families. The traditional use of some plant species (e.g. mallow, chamomile, wormwood) corresponds with findings from recent scientific literature. The large number of less studied plant species, such as white lupin as an antiparasitic herb, and Helleborus spp. as potential immunostimulatory agent, opens an interesting field for future research.

Conclusions: In general, EuEVM provides interesting treatment approaches for gastrointestinal and dermatological disorders as well as parasitosis. Findings regarding disorders of female genital or respiratory tract are less consistent. Nevertheless, EuEVM offers a solid basis for stimulating research in veterinary phytotherapy in Europe with a perspective to solve animal health problems in organic or even nonorganic ruminant production.

背景:欧共体有机农业法规规定有机牲畜最好使用植物治疗产品。尽管有机牲畜在欧洲非常重要,主要是反刍动物,但今天几乎没有植物治疗产品注册用于牲畜。此外,关于兽医植物疗法的信息很少。本文的目的是在欧洲民族兽医(EuEVM)研究结果的基础上,寻找应对欧洲有机反刍动物健康问题的方法。方法:利用Scopus数据库系统检索民族生物医学文献,对来自欧洲国家的75篇有关民族兽医信息的文献进行分析。结果:目前已报道的用于动物治疗的植物共有102科590种,以菊科、豆科和兰科为主要科。一些植物物种(如锦葵、洋甘菊、艾草)的传统用途与最近的科学文献的发现相一致。大量研究较少的植物物种,如作为抗寄生虫草药的白露,以及作为潜在免疫刺激剂的海勒草,为未来的研究开辟了一个有趣的领域。结论:总的来说,EuEVM为胃肠道和皮肤疾病以及寄生虫病提供了有趣的治疗方法。关于女性生殖器或呼吸道疾病的研究结果不太一致。尽管如此,EuEVM为促进欧洲兽医植物疗法的研究提供了坚实的基础,以期解决有机甚至非有机反刍动物生产中的动物健康问题。
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引用次数: 87
[Solidagoren® Liquid in uncomplicated urinary tract infections]. 【Solidagoren®液体治疗无并发症尿路感染】。
Pub Date : 2014-01-01
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引用次数: 0
Using hospital data and routines to estimate costs and effects of integrative care programmes for chronic pain and stress disorders--a feasibility study. 利用医院数据和惯例估算慢性疼痛和应激障碍综合护理方案的成本和效果——可行性研究。
Pub Date : 2014-01-01 Epub Date: 2014-06-16 DOI: 10.1159/000363635
Tobias Sundberg, Torkel Falkenberg

Background: Evidence of cost and effects for comprehensive hospital-based integrative care (IC) is scarce. The aim of this study was to explore the feasibility of using local hospital data and routines to estimate costs and effects of anthroposophic IC programmes for chronic pain and stress disorders in Sweden.

Methods: Retrospective analysis of one IC hospital's local administrative registry data. Main outcomes embraced patient demographics, programme duration and costs, patients' health status (EQ-5D index, 0-1) and self-rated health (EQ-5D VAS, 0-100), from hospital admittance to discharge. The use of postal questionnares for collecting follow-up data after hospital discharge was assessed.

Results: The IC pain programme had 461 records, all with complete data on costs and duration: average programme cost, EUR 5,925 (95% CI 5,780-6,070), and duration, 17.8 (SD 4.7) days. The IC stress programme had 263 records, all with complete cost and duration data: programme cost, EUR 5,494 (95%CI 5,318-5,671); duration 18.0 (SD 4.7) days. From admittance to discharge, health status improved by 0.23 (95% CI 0.19-0.27) in the pain, and by 0.16 (95% CI 0.12-0.20) in the stress programme. Improvements in self-rated health were 20 (95% CI 18-22), and 21 (95% CI 18-23), respectively. There was a general decrease in questionnaire response rate after hospital discharge, whereby 27-32% of respondents had completed data after 9 months.

Conclusions: It was feasible to use hospital registry data to estimate costs and show positive effects of anthroposophic IC programmes for pain and stress disorders in Sweden. Clinical implications and the need for long-term follow-up are discussed.

背景:基于医院的综合护理(IC)的成本和效果的证据很少。本研究的目的是探讨利用当地医院数据和常规来估计瑞典慢性疼痛和应激障碍的人智IC方案的成本和效果的可行性。方法:回顾性分析某IC医院的地方行政登记资料。主要结局包括患者人口统计、项目持续时间和成本、患者健康状况(EQ-5D指数,0-1)和自评健康(EQ-5D VAS, 0-100),从入院到出院。评估了使用邮寄问卷收集出院后随访数据的情况。结果:IC疼痛方案有461条记录,所有记录都有成本和持续时间的完整数据:平均方案成本为5,925欧元(95% CI 5,780-6,070),持续时间为17.8 (SD 4.7)天。IC压力计划有263条记录,所有记录都有完整的成本和持续时间数据:计划成本,5,494欧元(95%CI 5,318-5,671);持续时间18.0 (SD 4.7)天。从入院到出院,疼痛组健康状况改善了0.23 (95% CI 0.19-0.27),应激组健康状况改善了0.16 (95% CI 0.12-0.20)。自评健康的改善分别为20 (95% CI 18-22)和21 (95% CI 18-23)。出院后问卷回复率普遍下降,其中27-32%的受访者在9个月后完成了数据。结论:在瑞典,使用医院登记数据来估计成本并显示人智IC方案对疼痛和应激障碍的积极影响是可行的。临床意义和需要长期随访讨论。
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引用次数: 6
期刊
Forschende Komplementarmedizin
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