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In Vitro Evaluation of a Device to Assess Acetabular Cup Position by Sagittal Plane Radiography. 矢状面造影评估髋臼杯位置装置的体外评价。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2651-6297
W Michael Karlin, Ross Lirtzman, Michael P Kowaleski

The purpose of this study was to compare the calculated angle of lateral opening (ALO) and open-face version obtained using an acetabular cup position assessment device (CPAD) to the known ALO and open-face version of an acetabular component. The null hypothesis was that there would be no significant differences between the ALO and open-face versions using the CPAD compared with the known values.Radiographic images simulating a sagittal plane pelvis were obtained with a BFX™ acetabular component containing a CPAD mounted on a plexiglass jig with a dual-plane inclinometer. Images were obtained at an open-face version of 0 degrees with ALO at 30, 40, 45, 50, and 60 degrees, repeated in triplicate, and were randomized. Measurements of the CPAD bars were used to calculate the open-face version, and ALO measurements were compared using a paired t-test with a p-value set at p < 0.05. Agreement was assessed with a Lin's Concordance Correlation Coefficient.The calculated ALO was not significantly different from the known ALO (p = 0.608) and showed near-perfect correlation of the ALO with a Lin's Concordance Correlation Coefficient (R c value) of 0.994. The calculated open-face version was significantly different from the known version.The results demonstrate that the CPAD is an accurate method to determine ALO in a simulated sagittal plane pelvis radiographic view.

本研究的目的是比较使用髋臼杯位置评估装置(CPAD)获得的外侧开口(ALO)和开放面版本的计算角度与已知的髋臼假体的外侧开口(ALO)和开放面版本。原假设是,与已知值相比,使用CPAD的ALO和开放式版本之间没有显着差异。模拟矢状面骨盆的x线摄影图像是用BFX™髋臼组件获得的,该组件包含一个CPAD,安装在带有双平面倾角计的有机玻璃夹具上。图像在0度的开放面版本获得,在30度,40度,45度,50度和60度的ALO,重复三次,随机化。使用CPAD棒的测量值来计算开放面版本,使用配对t检验(p = 0.608)比较ALO测量值,结果显示ALO与Lin’s一致性相关系数(R c值)接近完美相关为0.994。计算出的开放面版本与已知版本有显著差异。结果表明,CPAD是一种准确的方法来确定模拟矢状面骨盆x线片上的ALO。
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引用次数: 0
Effect of Fluorescence Biomodulation on Dermal Healing in an Equine Experimental In Vivo Wound Model. 荧光生物调节对马实验性体内创面模型真皮愈合的影响。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-08-26 DOI: 10.1055/a-2655-9312
Avery Loyd, Rachel Neto, Fred Caldwell, Lindsey Boone, Amelia White

This study aimed to determine the safety and macroscopic/microscopic effects of fluorescence biomodulation (FBM) on experimentally induced, full-thickness, distal limb wounds in horses.This was an in vivo experimental study (n = 6 horses). Two full-thickness wounds were created on both dorsal metacarpi of six adult horses. Each forelimb was randomly allocated to either control (no FBM) or treatment (FBM) and randomly allocated to visual or histological assessment of healing. Wounds were treated within each experimental group every 7 days for four treatments. Fluorescence biomodulation wounds were treated twice per treatment period. Control wounds had no FBM treatment. Wounds were visually assessed for granulation tissue grading and photographed for wound surface area calculation, on days 3, 10, 17, 24 and 31. The skin from wound creation on day 0 was used for histology baseline. The wounds were then punch-biopsied on days 10, 17, 24 and 31. Data were analysed using linear mixed model analyses.Differences between control and treatment were not observed for any time point for wound surface area (p = 0.755), composite wound scores (p = 0.593), or histological assessment (p = 0.378). One horse produced exuberant granulation tissue in all wounds requiring debridement at study completion.Fluorescence biomodulation did not improve nor impair healing in an equine experimental in vivo distal limb wound model. Treatment effects may not have been observed due to small sample size, outcome variables measured or species differences. Further studies are needed.

本研究旨在确定荧光生物调节(FBM)对实验诱导的马远端肢体全层损伤的安全性和宏观/微观影响。这是一项体内实验研究(n = 6匹马)。在六匹成年马的双背掌骨上创造了两处全层伤口。每个前肢被随机分配到对照组(无FBM)或治疗组(FBM),并随机分配到视觉或组织学愈合评估组。各组创面每7 d处理一次,共4次。荧光生物调节创面在每个治疗期治疗2次。对照伤口未行FBM治疗。在第3、10、17、24和31天,对伤口进行肉芽组织分级和拍照以计算伤口表面积。创面第0天皮肤作为组织学基线。然后在第10、17、24和31天对伤口进行穿孔活检。数据分析采用线性混合模型分析。对照组和治疗组在创面面积(p = 0.755)、复合创面评分(p = 0.593)或组织学评估(p = 0.378)的任何时间点均无差异。在研究结束时,一匹马在所有需要清创的伤口上产生了丰富的肉芽组织。荧光生物调节既没有改善也没有损害马远端肢体创伤模型的愈合。由于样本量小、测量的结果变量或物种差异,可能没有观察到治疗效果。需要进一步的研究。
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引用次数: 0
Incidence of Bandage-Associated Complications in Cats following Clean Orthopaedic Procedures: A Retrospective Study of 152 Cases. 猫咪清洁矫形手术后绷带相关并发症的发生率:152例回顾性研究。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-31 DOI: 10.1055/a-2655-9218
Debbie Clayton, Sorcha Costello, Melanie Olive, Andrew S Levien, QiCai Jason Hoon, Jun R Loh, Alen Lai, King Mac, Evelyn Hall, Rachel M Basa

To report the incidence of bandage-associated complications in cats following clean orthopaedic injury.Multi-institutional retrospective case series of 152 client-owned cats. Medical records were searched for cats that had a bandage placed after a clean orthopaedic injury. Data collected included: signalment, diagnosis, anatomical region, orthopaedic procedure, professional role of the person applying the bandage (specialist/resident/nurse), bandage duration, complications, and outcomes.A total of 152 cats had bandages placed after clean orthopaedic injuries. Complications were reported in 104 cats (68.4%). Bandage-related complications were mild in 64.4% cases, moderate in 32.7% cases, and severe 2.9% of cases. If a cat had a splint placed, it was 3.4 times more likely to have a more severe complication compared with a cat which did not require a splint.Bandage complications occur frequently in cats, and the use of splints was a significant predictor of increased complication severity. Clinicians should be particularly vigilant when bandaging limbs in cats, as complications secondary to bandaging occur frequently. These findings underscore the importance of appropriate case selection for bandage application and monitoring strategies to minimize the risk of complications.

目的报道猫咪清洁骨科损伤后绷带相关并发症的发生率。152只客户养猫的多机构回顾性病例系列。研究人员搜索了在干净的骨科损伤后使用绷带包扎的猫的医疗记录。收集的数据包括:信号、诊断、解剖区域、矫形手术、使用绷带者的专业角色(专科医生/住院医生/护士)、绷带使用时间、并发症和结果。总共有152只猫在干净的骨科损伤后使用了绷带。104只猫出现并发症(68.4%)。绷带相关并发症轻度占64.4%,中度占32.7%,重度占2.9%。如果一只猫装了夹板,它出现严重并发症的可能性是没有装夹板的猫的3.4倍。绷带并发症在猫中经常发生,夹板的使用是并发症严重程度增加的重要预测因素。临床医生在对猫进行四肢包扎时应特别警惕,因为包扎后的并发症经常发生。这些发现强调了适当的病例选择绷带应用和监测策略的重要性,以尽量减少并发症的风险。
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引用次数: 0
Feasibility of Integrating Locking Plate System into Additively Manufactured Implants: A Mechanical Comparison of Three-Dimensional-Printed and Machined Locking Hole Threads. 将锁紧板系统集成到增材制造植入物中的可行性:三维打印锁紧孔螺纹和机械加工锁紧孔螺纹的力学比较。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-23 DOI: 10.1055/a-2654-8833
Kyu-Won Kang, Sunyoung Kim, Byung-Jae Kang

This study integrated a locking plate system into three-dimensional (3D)-printed implants and evaluated whether directly 3D-printed locking plate holes could achieve mechanical performance comparable to their machined counterpart. In vitro mechanical tests were performed to compare a 3D-printed 3.5-mm locking plate system with a commercially available variable-angle locking system (ARIX). Locking plate specimens (n = 90) were 3D printed from Ti6Al4V in three build orientations (0, 45 and 90 degrees). A torque limit test assessed the failure points under three screw insertion torques (0.6, 1.1 and 2.0 Nm) at two angles (0 and 15 degrees). The locked screw-and-plate constructs then underwent push-out testing, with a load applied parallel to the screw axis.At 2.0 Nm, all 3D-printed specimens failed due to thread deformation, whereas the ARIX system remained intact. Specimens printed at 0-degree orientation had the highest push-out strength, comparable to ARIX plates, while those printed at 90 degrees showed significantly lower strength. A higher insertion torque (1.1 Nm) improved the push-out strength regardless of screw angulation. Low torque with angled screws led to a substantial reduction in push-out strength.The directly 3D-printed locking plate system achieved a comparable mechanical performance to machined counterparts when printed at 0-degree orientation, with appropriate torque. Optimal build orientation and careful control of insertion torque are crucial for maximizing the performance of 3D-printed locking plates.

本研究将锁定板系统集成到三维(3D)打印的植入物中,并评估直接3D打印锁定板孔是否可以达到与机械加工相媲美的机械性能。我们进行了体外力学测试,将3d打印的3.5 mm锁定板系统与市售的可变角度锁定系统(ARIX)进行比较。用Ti6Al4V 3D打印锁定板样品(n = 90),三个构建方向(0度,45度和90度)。扭矩极限测试评估了三个螺钉插入扭矩(0.6,1.1和2.0 Nm)在两个角度(0和15度)下的失效点。锁定螺钉-钢板结构然后进行推出测试,施加平行于螺钉轴的载荷。在2.0 Nm时,所有3d打印的样品由于螺纹变形而失效,而ARIX系统保持完整。以0度方向打印的样品具有最高的推出强度,与ARIX板相当,而以90度方向打印的样品强度明显较低。更高的插入扭矩(1.1 Nm)提高了推出强度,无论螺杆角度如何。低扭矩与角度螺钉导致推出强度大幅降低。直接3d打印的锁紧板系统在0度方向上打印时,具有与机械加工的锁紧板相当的机械性能,并具有适当的扭矩。优化构建方向和仔细控制插入扭矩对于最大化3d打印锁紧板的性能至关重要。
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引用次数: 0
Temporary Transarticular Immobilization of the Stifle Joint Using a Locking Plate. 用锁定钢板对膝关节进行临时经关节固定。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-04-30 DOI: 10.1055/a-2577-1520
Ida Forzisi, Alessio Raschi, Aldo Vezzoni, Luca Vezzoni

Our study aims to describe the surgical technique for temporary transarticular immobilization of the stifle joint using a locking plate and evaluate complications and outcomes.The medical records of dogs and cats that underwent transarticular immobilization of the stifle joint using a locking plate in two institutions from August 2018 to January 2024 were retrospectively evaluated.After managing the primary injury, a locking plate was contoured to fit the medial surface of the distal femur and proximal tibia, limiting the implant to the distal third of the femur and proximal third of the tibia, with immobilization at a 135 to 145-degree angle.Temporary transarticular immobilization of the stifle joint was performed in 16 stifle joints in 14 patients, with two dogs undergoing bilateral surgery. The transarticular implants were removed at a mean time of 55,86 ± 18,05 days postoperatively (median: 58, range: 27-96 days). No intraoperative complications were recorded. One major complication was recorded in a Galgo Espanol with a patellar fracture and patellar ligament lesion in which plate breakage was recorded 19 days after surgery, requiring early plate removal and application of an orthosis for 3 weeks. Four minor complications were recorded.Preliminary results suggest that a transarticular locking plate is effective for temporary stifle immobilization, with a low morbidity and complication rate. Dedicated implants should be developed to decrease the risk of plate failure.

我们的研究旨在描述使用锁定钢板临时经关节固定膝关节的手术技术,并评估并发症和结果。回顾性分析了2018年8月至2024年1月在两个机构使用锁定钢板进行经关节固定的狗和猫的医疗记录。在处理原发性损伤后,将锁定钢板塑形以适应股骨远端和胫骨近端内侧表面,将植入物限制在股骨远端三分之一和胫骨近端三分之一,并以135至145度角固定。对14例患者的16个膝关节进行了临时经关节固定,其中2只狗接受了双侧手术。术后平均55,86±18,05天(中位数:58,范围:27-96天)取出经关节植入物。无术中并发症记录。一个主要的并发症是Galgo Espanol,髌骨骨折和髌骨韧带病变,术后19天记录了钢板断裂,需要早期取下钢板并使用矫形器3周。记录了4例轻微并发症。初步结果表明,经关节锁定钢板是一种有效的临时膝关节固定,发病率和并发症发生率低。应开发专用植入物以降低钢板失效的风险。
{"title":"Temporary Transarticular Immobilization of the Stifle Joint Using a Locking Plate.","authors":"Ida Forzisi, Alessio Raschi, Aldo Vezzoni, Luca Vezzoni","doi":"10.1055/a-2577-1520","DOIUrl":"10.1055/a-2577-1520","url":null,"abstract":"<p><p>Our study aims to describe the surgical technique for temporary transarticular immobilization of the stifle joint using a locking plate and evaluate complications and outcomes.The medical records of dogs and cats that underwent transarticular immobilization of the stifle joint using a locking plate in two institutions from August 2018 to January 2024 were retrospectively evaluated.After managing the primary injury, a locking plate was contoured to fit the medial surface of the distal femur and proximal tibia, limiting the implant to the distal third of the femur and proximal third of the tibia, with immobilization at a 135 to 145-degree angle.Temporary transarticular immobilization of the stifle joint was performed in 16 stifle joints in 14 patients, with two dogs undergoing bilateral surgery. The transarticular implants were removed at a mean time of 55,86 ± 18,05 days postoperatively (median: 58, range: 27-96 days). No intraoperative complications were recorded. One major complication was recorded in a Galgo Espanol with a patellar fracture and patellar ligament lesion in which plate breakage was recorded 19 days after surgery, requiring early plate removal and application of an orthosis for 3 weeks. Four minor complications were recorded.Preliminary results suggest that a transarticular locking plate is effective for temporary stifle immobilization, with a low morbidity and complication rate. Dedicated implants should be developed to decrease the risk of plate failure.</p>","PeriodicalId":51204,"journal":{"name":"Veterinary and Comparative Orthopaedics and Traumatology","volume":" ","pages":"141-146"},"PeriodicalIF":1.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implantation of a Canine Total Ankle Replacement Prosthesis Using a Lateral Surgical Approach is Accurate and Leads to a Stable Joint. 采用外侧手术入路植入犬全踝关节置换假体是准确的,并导致关节稳定。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-25 DOI: 10.1055/a-2654-8080
Michelle M Zingel, Laurent P Guiot, Denis J Marcellin-Little, Tanya C Garcia, Jennifer L Hubbard

This study aimed to determine if canine total ankle replacement (cTAR) can be performed using a lateral surgical approach by comparing implant orientation, limb orientation and tarsocrural stability after implantation using a lateral or medial approach.Ten cadaveric limbs from five large-breed dogs were implanted with a cTAR prosthesis using a medial or a lateral approach. Caudocranial and mediolateral radiographs were obtained. Joint orientation, limb orientation, angular tarsocrural stability (varus and valgus laxity) and rotational tarsocrural stability (internal and external rotational laxity) were measured before and after implantation and compared. Polar gaps around cTAR components were measured.Before implantation, mean valgus laxity was 1.8 degrees larger in limbs which were implanted with a cTAR prosthesis using a lateral approach than in limbs implanted using a medial approach. After a lateral approach, mean valgus laxity was 4.4 degrees larger (7.2 degrees) than before (2.8 degrees), and mean external rotational laxity was 5.4 degrees larger (10.7 degrees) than before (5.3 degrees). After a medial approach, mean external rotational laxity was 6.7 degrees larger (11.6 degrees) than before (4.9 degrees). The mean angular laxity was 6.0 degrees larger after a lateral approach (15.5 degrees) than a medial approach (9.5 degrees). Significant differences among other measurements collected after a lateral or medial approach were not identified.A cTAR prosthesis can be implanted using a lateral approach and result in a properly oriented tarsocrural joint that is rotationally stable and has slight angular laxity.

本研究旨在通过比较外侧入路或内侧入路植入后的植入物取向、肢体取向和跗骨稳定性,确定犬全踝关节置换术(cTAR)是否可以采用外侧手术入路进行。采用内侧或外侧入路将5只大型犬的10只尸体肢体植入cTAR假体。获得尾颅和中外侧x线片。在植入前后测量关节定向、肢体定向、角跗骨稳定性(内翻和外翻松弛)和旋转跗骨稳定性(内、外旋转松弛)并进行比较。测量了cTAR组分周围的极性间隙。植入前,采用外侧入路植入cTAR假体的肢体平均外翻松弛度比采用内侧入路植入假肢的肢体大1.8度。侧入路后,平均外翻松弛度比前(2.8度)大4.4度(7.2度),平均外旋松弛度比前(5.3度)大5.4度(10.7度)。内侧入路后,平均外旋松弛度比前(4.9度)大6.7度(11.6度)。侧入路(15.5度)比内侧入路(9.5度)平均角松弛度大6.0度。在外侧入路或内侧入路后收集的其他测量数据之间没有明显差异。cTAR假体可以通过外侧入路植入,形成一个旋转稳定且角度轻微松弛的正确定向的跗关节。
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引用次数: 0
Canine Haemophilic Arthropathy: Magnetic Resonance Imaging and Histologic Assessment of Joints in Two Adult Beagles with Confirmed Factor Deficiencies. 犬血友病关节病:磁共振成像和组织学评估的两个成年比格犬关节证实因子缺乏。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-03-01 Epub Date: 2025-07-25 DOI: 10.1055/a-2654-8450
Sarah L Pownder, Brian G Caserto, Marjory B Brooks, Kei Hayashi

Two adult female Beagle dogs, one case each of hereditary Factor VII deficiency and Factor IX deficiency, were evaluated post-mortem for joint pathology associated with haemophilic arthropathy (HA) using magnetic resonance imaging and histology. Cadaveric magnetic resonance imaging and histologic findings demonstrated severe HA for the Factor IX deficiency dog, with only mild abnormalities for the Factor VII deficiency dog. Signs of HA were similar to humans, including cartilage degeneration, subchondral cysts, peripheral erosions, neovascularization, synovial inflammation and hyperplasia, hemosiderin deposition, haematoma and osteoporosis. Magnetic resonance imaging examination can be used to help identify features of HA in dogs that have experienced repeated joint bleeds.

两只成年雌性Beagle犬,遗传因子7缺乏症和因子9缺乏症各1例,死后使用磁共振成像和组织学评估与血友病关节病(HA)相关的关节病理。尸体磁共振成像和组织学结果显示,因子IX缺乏症犬有严重的血凝素,因子VII缺乏症犬只有轻微异常。HA的症状与人类相似,包括软骨退变、软骨下囊肿、外周糜烂、新生血管形成、滑膜炎症和增生、含铁血黄素沉积、血肿和骨质疏松。磁共振成像检查可用于帮助识别反复关节出血的犬HA的特征。
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引用次数: 0
Gap Formation in Achilles Tendon Reinsertion in Cats: A Comparative Ex Vivo Study of Bone Tunnel and a Bioabsorbable Suture Anchor. 猫跟腱再插入间隙的形成:骨隧道和生物可吸收缝合锚的比较离体研究。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-02-24 DOI: 10.1055/a-2812-5029
Felix Groß, Katja Haslinger-Vaughan, Philipp J Thurner, Riccarda Schuenemann

This study aimed to compare gap formation between a classical transcalcaneal bone tunnel and a bioabsorbable suture anchor in a feline Achilles tendon avulsion model.Gastrocnemius tendons were dissected from the calcaneus of seven pairs of feline gastrocnemius tendon-calcaneus specimens. Reinsertion was performed either through a transverse bone tunnel or with a bioabsorbable suture anchor with a metric 3 non-absorbable monofilament polypropylene-polyethylene suture in a Bunnell-Mayer pattern. Tensile tests were conducted under physiological loading conditions. Gap formation was tracked with a video camera, and force on the tendon was measured. Results were compared with t-tests.Mean load at a gap of 0.5 mm was significantly higher for the suture anchor (44.2 ± 5.5 N) compared with the bone tunnel (23.0 ± 15.4 N). A 3-mm gap was not reached with the suture anchor. Failure loads were dominated by suture breakage and were not significantly different between suture anchor (55.2 ± 8.0 N) and bone tunnel (65.1 ± 8.3 N). Pulling through the tendon substance did not occur.The suture anchor resisted gap formation more effectively than the bone tunnel and can be considered advantageous for gastrocnemius tendon reinsertion in cats.

本研究旨在比较经典经肩胛骨隧道和生物可吸收缝合锚在猫跟腱撕脱伤模型中的间隙形成。本文从7对猫腓肠肌肌腱-跟骨标本的跟骨上解剖腓肠肌肌腱。通过横骨隧道或生物可吸收缝线锚钉进行重新插入,缝线锚钉采用3米制不可吸收单丝聚丙烯-聚乙烯缝线,符合Bunnell-Mayer模式。拉伸试验在生理加载条件下进行。用摄像机跟踪间隙的形成,并测量肌腱上的力。结果采用t检验进行比较。缝线锚钉在0.5 mm间隙处的平均载荷(44.2±5.5 N)明显高于骨隧道(23.0±15.4 N)。缝合锚没有达到3mm的间隙。破坏载荷以缝线断裂为主,缝线锚钉(55.2±8.0 N)与骨隧道(65.1±8.3 N)间无显著差异。没有发生撕裂肌腱物质的情况。缝线锚钉比骨隧道更有效地抵抗间隙的形成,可以认为对猫腓肠肌肌腱再插入是有利的。
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引用次数: 0
In Silico Morphometric Analysis of the Tibia Following Four Virtual Proximal Levelling Osteotomies for the Treatment of Canine Cranial Cruciate Ligament Rupture. 犬颅交叉韧带断裂四次近端截骨术后胫骨的计算机形态学分析。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-02-02 DOI: 10.1055/a-2789-2371
Isabel de Marcos Carpio, Felipe de Vicente, Rosario Vallefuoco

(1) To describe and compare the morphometric changes of the tibia following four virtual proximal tibial osteotomies for treatment of canine cranial cruciate ligament deficiency and (2) to determine how these changes are affected by the initial tibial plateau angle (TPA).A total of 30 mediolateral radiographic views of canine stifle were selected. A dedicated radiographic digital planning software was used to virtually perform four osteotomy techniques for each case: tibia plateau levelling osteotomy (TPLO), cranial closing wedge osteotomy (CCWO), modified cranial closing wedge osteotomy (mCCWO), and centre of rotation of angulation-based levelling osteotomy (CBLO). Changes in tibial length, anatomical-mechanical axis angle (AMA angle), proximal tibial angulation, and patellar ligament insertion point were measured and compared.All the parameters evaluated were significantly affected by the osteotomy technique and the initial TPA. Mean ± SD of tibial length pre-simulation was 174.2 ± 23.6 mm, and the largest significant reduction was observed after mCCWO (169.6 ± 23.3 mm) (P < 0.001). Mean ± SD of AMA angle pre-simulation was 3.1 ± 1.4 degrees and a significant reduction was observed after CCWO (1.1 ± 0.16 degrees) (P = 0.0782), but there was no significant difference among treatments. Mean ± SD of the distal tibia axis/proximal tibial axis (DTA/PTA) angle pre-simulation was 4.5 ± 2.8 degrees, and the biggest significant reduction was seen with CBLO (-10.94 ± 0.65) (P < 0.0001). The cranial and distal shift of the patellar ligament insertion point was significant after CCWO (P = 0.0004, P < 0.0001 respectively), mCCWO (P = 0.0001, P < 0.0001 respectively), and CBLO (P = 0.03, P = 0.0006 respectively) osteotomy techniques.Proximal tibial osteotomy techniques cause morphometric changes of the tibia, and a steeper TPA exacerbates these changes. TPLO caused the fewest morphometric changes. Further investigations are warranted to understand the clinical implications on the biomechanics of the stifle.

(1)描述和比较四次胫骨近端截骨术治疗犬颅交叉韧带缺乏症后胫骨的形态变化;(2)确定这些变化如何受到初始胫骨平台角(TPA)的影响。共选择30张犬膝关节的中外侧x线片。使用专用的放射学数字规划软件对每个病例虚拟执行四种截骨技术:胫骨平台水平截骨术(TPLO),颅骨闭合楔形截骨术(CCWO),改良颅骨闭合楔形截骨术(mCCWO)和旋转中心基于角度的水平截骨术(CBLO)。测量并比较胫骨长度、解剖-机械轴角(AMA角)、胫骨近端角度、髌骨韧带止点的变化。截骨术和初始TPA对所有参数均有显著影响。预模拟胫骨长度的平均值±SD为174.2±23.6 mm, mCCWO后胫骨长度减少幅度最大(169.6±23.3 mm) (P = 0.0782),但两组间差异无统计学意义。胫骨远端轴/胫骨近端轴(DTA/PTA)角预模拟的平均值±SD为4.5±2.8度,CBLO截骨术降低幅度最大(-10.94±0.65)(P = 0.0004, P = 0.0001, P = 0.03, P = 0.0006)。胫骨近端截骨术引起胫骨的形态改变,更陡的TPA加剧了这些变化。TPLO引起的形态学变化最小。需要进一步的研究来了解膝关节生物力学的临床意义。
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引用次数: 0
Naturally Occurring Secondary Renal Hyperparathyroidism and Fibrous Osteodystrophy in a Pet Rabbit (Oryctolagus cuniculus). 宠物兔(Oryctolagus cuuniculus)自然发生的继发性肾甲状旁腺功能亢进和纤维性骨营养不良。
IF 1.1 2区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2026-01-30 DOI: 10.1055/a-2789-2474
Johanna Mäkitaipale, Udo Hetzel, Niina Airas

Rabbits with end-stage kidney failure often develop hypercalcaemia and osteosclerosis. Secondary renal hyperparathyroidism and fibrous osteodystrophy can be experimentally induced in rabbits through nephrectomy and a low-calcium:high-phosphorus diet, but clinical case reports are rare. A thin, mixed-breed, neutered male rescue rabbit was brought to a veterinary clinic due to lameness of the right hind limb and gait difficulties. Radiographs showed severe osteodystrophy. Additionally, there was a displaced, ununited simple fracture in the right mid-femur and a healed simple fracture in the right mid-tibia. Dentition was normal. The rabbit was euthanized. Blood tests revealed mildly elevated urea (12.3 mmol/mL), glucose (10.6 mmol/L), and alkaline phosphatase (179 mmol/L). High levels of serum parathyroid hormone (281.1 pg/mL) and a 25-hydroxyvitamin D concentration of 11.2 ng/mL were also noted. Creatinine was 105 µmol/L and inorganic phosphate was 1.53 mmol/L. Bone density in the mid-tibia was very low (934.6 mg/cm3). Tests for Encephalitozoon cuniculi antibodies were negative. Post-mortem examination showed severe chronic renal interstitial fibrosis and severe bilateral parathyroid hyperplasia. This case report highlights the novel finding that secondary renal hyperparathyroidism and fibrous osteodystrophy, accompanied by pathological fractures, can manifest as sequelae of end-stage renal disease in rabbits. This revelation is clinically significant and should be carefully considered by veterinarians when managing older rabbits presenting with fractures.

终末期肾衰竭的兔子经常出现高钙血症和骨硬化。继发性肾甲状旁腺功能亢进和纤维性骨营养不良可通过兔肾切除术和低钙高磷饮食实验诱导,但临床病例报道罕见。由于右后肢跛行和步态困难,一只瘦弱,杂交,绝育的雄性救援兔被带到兽医诊所。x线片显示严重的骨营养不良。此外,右侧股骨中部有移位、不愈合的单纯性骨折,右侧胫骨中部有愈合的单纯性骨折。牙列正常。这只兔子被安乐死了。血液检查显示尿素(12.3 mmol/mL)、葡萄糖(10.6 mmol/L)和碱性磷酸酶(179 mmol/L)轻度升高。血清甲状旁腺激素水平高(281.1 pg/mL), 25-羟基维生素D浓度为11.2 ng/mL。肌酐105µmol/L,无机磷酸盐1.53 mmol/L。胫骨中部骨密度极低(934.6 mg/cm3)。脑膜虫抗体试验均为阴性。尸检显示严重的慢性肾间质纤维化和严重的双侧甲状旁腺增生。本病例报告强调了继发性肾甲状旁腺功能亢进和纤维性骨营养不良,伴有病理性骨折,可以表现为终末期肾脏疾病的兔的后遗症的新发现。这一发现具有临床意义,兽医在处理出现骨折的老年兔子时应仔细考虑。
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Veterinary and Comparative Orthopaedics and Traumatology
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