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Calculation of Absorbed Dose of 103Pd and 131Cs Sources in Prostate Cancer Brachytherapy Simulation Using Monte Carlo N-Particle 6 (MCNP-6) Software 使用 Monte Carlo N-Particle 6 (MCNP-6) 软件计算前列腺癌近距离治疗模拟中 103Pd 和 131Cs 源的吸收剂量
Pub Date : 2024-04-16 DOI: 10.4028/p-g56t9j
Mumung Ridhuan Munggara, Nita Handayani, Fajar Arianto
Implant brachytherapy is one of the therapies for Low Dose Rate (LDR) in prostate cancer. This type of therapy uses a source with low energy and penetration rate so that the organs around the prostate do not receive much of the absorbed dose. This study uses a calculation method Monte Carlo N-Particle 6 (MCNP-6) to calculate the interaction of photons with organ materials. The main objective of this research is to determine the number of seeds and the ideal source activity to achieve the optimal absorbed dose in the prostate and provide the minimum absorbed dose in the surrounding organs. Organs around the prostate include the testes, small intestine, descending colon wall, descending colon, sigmoid colon wall, bladder wall, and bladder. This study uses two types of radioisotope sources namely 103Pd and 131Cs which each has a photon energy of 21 keV and 30 keV. Variations made is the addition of the number of seeds from 60 to 100 at intervals of 8 seeds symmetrically away from the center of the prostate and variation of source activity from 0.1 mCi to 0.6 mCi at intervals of 0.1 mCi for each type of source. Results of this study obtained the relationship that the more the number of seeds the greater the dose received by the prostate and surrounding organs, as well as the addition of source activity. The effect of increasing the number of seeds can increase the absorbed dose more significantly than the effect of adding activity to the organs around the prostate. Optimal absorbed dose for 103Pd is 125 Gy and 115 Gy for 131Cs. Based on the simulation results with MCNP-6, it is obtained that the ideal combination for the optimal absorbed dose is obtained from the source 103Pd is the number of seed 60 with 0.3 mCi activity, and source 131Cs is the number of seed 76 with an activity of 0.5 mCi. Source 103Pd provides a lower absorbed dose to the organs around the prostate compared to the source 131Cs.
植入近距离放射治疗是前列腺癌低剂量率(LDR)疗法之一。这种疗法使用低能量和低穿透率的放射源,因此前列腺周围的器官吸收的剂量并不多。这项研究使用蒙特卡洛 N 粒子 6(MCNP-6)计算方法来计算光子与器官材料的相互作用。这项研究的主要目的是确定种子的数量和理想的光源活性,以达到前列腺的最佳吸收剂量,并使周围器官的吸收剂量最小。前列腺周围的器官包括睾丸、小肠、降结肠壁、降结肠、乙状结肠壁、膀胱壁和膀胱。这项研究使用两种放射性同位素源,即 103Pd 和 131Cs,它们的光子能量分别为 21 keV 和 30 keV。每种放射源的放射性活度从 0.1 mCi 到 0.6 mCi,每种放射源的放射性活度间隔为 0.1 mCi。研究结果表明,种子数量越多,前列腺和周围器官接收到的剂量就越大,同时放射源活性也会增加。与增加前列腺周围器官的活性相比,增加种子数量能更显著地增加吸收剂量。103Pd 的最佳吸收剂量为 125 Gy,131Cs 为 115 Gy。根据 MCNP-6 的模拟结果,可以得出最佳吸收剂量的理想组合是:103Pd 源为 60 粒活性为 0.3 mCi 的种子,131Cs 源为 76 粒活性为 0.5 mCi 的种子。与 131Cs 源相比,103Pd 源对前列腺周围器官的吸收剂量较低。
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引用次数: 0
Development Web-Based Economic Data Application of Nu DIY Using Extreme Programming 使用极限编程开发基于网络的 Nu DIY 经济数据应用程序
Pub Date : 2024-04-16 DOI: 10.4028/p-3iogwc
Dina Millatina, Hikmah Nursidik, Maulana Yusuf Ahmadi, M. G. Wonoseto
The Nahdlatul Ulama economic institution (LPNU) DIY needs data as soon as possible to be used as a reference in formulating policies in order to improve the welfare of its members. Researchers made the web-based NUEcon application for data collection on the NU DIY economy to help make it easier for LPNU DIY to collect data. The method used is extreme programming (XP). XP can accept changes with a short development time even in a small team. The test results show that NUEcon can help facilitate NU DIY economic data collection.
伊斯兰教祈祷团经济机构(LPNU) DIY 需要尽快获得数据,以便在制定政策时作为参考,从而改善其成员的福利。研究人员制作了基于网络的 NUEcon 应用程序,用于收集 NU DIY 经济的数据,以帮助 LPNU DIY 更容易地收集数据。使用的方法是极限编程(XP)。即使在一个小团队中,XP 也能在很短的开发时间内接受更改。测试结果表明,NUEcon 有助于促进 NU DIY 经济数据的收集。
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引用次数: 0
Molecular Simulation of Coffee Beans’ Natural Products as Lead Compounds for Stroke Remedy 咖啡豆天然产品的分子模拟--作为治疗中风的先导化合物
Pub Date : 2024-04-16 DOI: 10.4028/p-k5delo
Muhammad Rubani, A. Parikesit
The consumption of coffee has its health benefits and its risks, one of the risks is mostly related to cardiovascular diseases. One of the diseases is hypertension which is considered “the silent killer” as it is a serious condition which promotes other complications and typically has no symptoms for a period of time until it has done significant damage. Acute hypertension can lead to a stroke. It is a very serious medical condition where the blood flow to the brain is poor, causing the death of cells within the brain. Some medications, surgeries and other healthcare programs are capable of controlling stroke, but stroke still remains to be the main cause of death and disability in Indonesia. However, provided that the consumption is restrained, multiple studies show that coffee consumption actually can reduce the risk of getting a stroke, by consuming between 2 to 4 cups of coffee per day. Additionally, coffee can reduce the likelihood of blood clots from forming and is likely to alter the blood vessel physiology. Therefore, the current project will explore the possibility of utilization of bioactive compounds other than caffeine from coffee beans that can be implemented in a form of supplements to help in treating patients both with stroke symptoms and during the recovery phase. Protein docking analysis is an alternative way to search and predict for drug discovery. Through protein docking analysis we can gain information on the bioactive compounds and their respective interactions with the target. Based on the virtual screening pipeline, it is predicted that Dehydrokahweol could elicit possible lead for the anti-stroke activity.
喝咖啡对健康有好处,也有风险,其中一个风险主要与心血管疾病有关。其中一种疾病是高血压,它被认为是 "无声杀手",因为它是一种严重的疾病,会引发其他并发症,而且通常在一段时间内没有任何症状,直到造成重大损害。急性高血压可导致中风。这是一种非常严重的病症,脑部血流不畅,导致脑细胞死亡。一些药物、手术和其他医疗保健项目能够控制中风,但中风仍然是印尼人死亡和残疾的主要原因。然而,多项研究表明,只要控制饮用量,每天饮用2至4杯咖啡实际上可以降低中风的风险。此外,咖啡还能降低血栓形成的可能性,并有可能改变血管的生理结构。因此,本项目将探索利用咖啡豆中咖啡因以外的生物活性化合物的可能性,这些化合物可以以营养补充剂的形式使用,帮助治疗中风症状患者和恢复期患者。蛋白质对接分析是搜索和预测药物发现的另一种方法。通过蛋白质对接分析,我们可以获得生物活性化合物及其与靶标相互作用的信息。根据虚拟筛选管道,我们预测 Dehydrokahweol 可能具有抗中风活性。
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引用次数: 0
Value Stream Mapping in Crude Palm Oil Industry: A Brief Review 毛棕榈油产业价值流图:简要回顾
Pub Date : 2024-04-16 DOI: 10.4028/p-blliw9
Syamsul Anwar
To maintain its competitiveness, the Indonesian CPO industry must apply lean techniques such as value stream mapping (VSM) that can be utilized to increase the process efficiency. While there have been several studies which attempted to apply VSM techniques to the CPO industry, the results of these studies have not been summarized and compared. This paper aims to summarize the findings of previous VSM studies in Indonesian CPO industry and provide the directions for future researches. In this study, the brief literature review is applied in which the relevant articles are reviewed according to the scope of study, approach or method, and types of identified wastes. Various types of wastes found from the initial stage (FFB reception) to the final stage (CPO storage). The average process cycle efficiency score indicates the requirements for improvement actions. Recommendations for future VSM researches include the scope of the process stages studied, process mapping for future condition, and the requirements of green and sustainability aspects.
为了保持竞争力,印尼 CPO 行业必须应用精益技术,如价值流图 (VSM),以提高流程效率。虽然已有多项研究试图将 VSM 技术应用于 CPO 行业,但这些研究的结果尚未得到总结和比较。本文旨在总结以往印尼 CPO 行业 VSM 研究的结果,并为今后的研究提供方向。在本研究中,采用了简要文献综述的方法,根据研究范围、方法或途径以及确定的废物类型对相关文章进行了综述。从最初阶段(FFB 接收)到最后阶段(CPO 储存),发现了各种类型的废物。平均流程周期效率得分表明需要采取改进措施。对未来 VSM 研究的建议包括所研究工艺阶段的范围、未来条件的工艺映射以及绿色和可持续发展方面的要求。
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引用次数: 0
Cyber Crime Identifying Using Machine Learning Techniques - Based Sentiment Analysis 利用机器学习技术识别网络犯罪--基于情感分析
Pub Date : 2024-04-16 DOI: 10.4028/p-j46rcy
Yessi Yunitasari, Latjuba S.T.T. Sofyana, Maria Ulfah Siregar
Social media analytics is a form of information analytics that is quite important in today's cyber situation. Cybercrime is criminal behaviour based on computers and internet networks. Cybercriminals usually hack systems to obtain the personal information of victims. There are many types of cybercrimes. There are four types of cybercrimes: Phishing scams, Hacking, Cyber Stalking and Cyber Bullying. This research aims to help the process analysis by the Police or investigative institutions of the private sector in knowing the results of public sentiment on social media related to current cyber crimes. Ciber Crime identifying using machine learning techniques, based sentiment analysis. Method used for sentiment analysis related to cybercrime is Random Forest, Naïve Bayes, and KNN. The highest accuracy value of the three methods tried is the Naive Bayes algorithm of 99.45%. The highest precision value uses the Naive Bayes algorithm of 99.80%, and the highest recall value uses the random forest algorithm of 100%.
社交媒体分析是信息分析的一种形式,在当今的网络形势下相当重要。网络犯罪是基于计算机和互联网络的犯罪行为。网络犯罪分子通常通过入侵系统来获取受害者的个人信息。网络犯罪有许多类型。网络犯罪有四种类型:网络钓鱼诈骗、黑客攻击、网络跟踪和网络欺凌。本研究旨在帮助警方或私营部门的调查机构进行流程分析,了解公众在社交媒体上对当前网络犯罪的看法。使用基于情感分析的机器学习技术识别网络犯罪。用于网络犯罪相关情感分析的方法有随机森林法、奈夫贝叶斯法和 KNN 法。在尝试的三种方法中,准确率最高的是 Naive Bayes 算法,达到 99.45%。精度值最高的是 Naive Bayes 算法,为 99.80%,召回值最高的是随机森林算法,为 100%。
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引用次数: 0
6th International Conference on Science and Engineering (ICSE) 第六届国际科学与工程会议(ICSE)
Pub Date : 2024-04-16 DOI: 10.4028/b-aqml3y
Shofwatul Uyun, Khusna Dwijayanti, Hsiang-Lin Liu, Noor Baity Saidy, Muhammad Syafiq, Denni Kurniawan, Agessty Ika Nurlita, Andi Andi, Deddy Rahmadi, Dien F. Awaliyah, Dwi Otik Kurniawati, Gita Miranda Warsito, Mandahadi Kusuma, Priyagung Dhemi Widiakongko, Siti Fatimah
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引用次数: 0
Bakpia Quality Control Analysis Using the Statistical Quality Control (SQC) Method (Case Study: SMEs Bakpia Latief, Kediri) 使用统计质量控制 (SQC) 方法对 Bakpia 质量控制进行分析(案例研究:克迭里省 Bakpia Latief 的中小型企业)
Pub Date : 2024-04-16 DOI: 10.4028/p-fzb5j6
Andika Yuli Heryanto
Bakpia is made from green beans and sugar wrapped in flour. Bakpia Latief Kediri is a bakpia industry in the City of Kediri. The company needs help in the production process activities. There are still products that need to be fixed. The types of it defects in the company are burnt and cracked. This study aimed to determine the performance of its quality control, determine the most dominant types of defects in its products, and provide suggestions for improving its production process. The research method uses the Statistical Quality Control method. Data is taken in the form of primary data and secondary data. Primary data was collected by interview and observation. Interviews were conducted using in-depth interviews. Observations were made for 30 days. Data analysis uses statistical tools, which include check sheets, histograms, fishbone diagrams, Pareto diagrams, and control charts p. Bakpia quality control at Bakpia Latief is under control because the p chart control chart shows that only one point is out of the control limits. The most dominant defect in its products is burnt, with an average percentage of 0.617%. Corrective actions to reduce the existence of defective products, namely repairing and maintaining production machines, improving the stages of the production process, developing human resources, and repairing production facilities. Keywords: Product Defects, Quality Control, Statistical Quality Control
Bakpia 是用绿豆和糖裹在面粉里制成的。Bakpia Latief Kediri 是基迪里市的一家烘焙行业。该公司在生产过程中需要帮助。仍有一些产品需要修复。该公司的缺陷类型为烧焦和破裂。本研究旨在确定其质量控制的绩效,确定其产品中最主要的缺陷类型,并为改进其生产流程提供建议。研究方法采用统计质量控制法。数据采用原始数据和二手数据的形式。原始数据通过访谈和观察收集。访谈采用深度访谈。观察期为 30 天。数据分析使用统计工具,包括核对表、直方图、鱼骨图、帕累托图和控制图 p. Bakpia Latief 的质量控制处于受控状态,因为 p 图控制图显示只有一个点超出了控制范围。其产品中最主要的缺陷是烧焦,平均比例为 0.617%。为减少缺陷产品的存在而采取的纠正措施,即修理和维护生产机器、改进生产过程的各个阶段、开发人力资源和修理生产设施。关键词产品缺陷、质量控制、统计质量控制
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引用次数: 0
Household Water Supply in Yogyakarta (Indonesia) and Hanoi (Vietnam) 日惹(印度尼西亚)和河内(越南)的家庭供水情况
Pub Date : 2024-04-16 DOI: 10.4028/p-o3cfvn
Arifah Khusnuryani, Eka Sulistiyowati
This research explores water users’ perceptions regarding access, quantity, quality and water treatments in urban area of Yogyakarta and Hanoi. This research’s approach is qualitative and descriptive. The case studied was in the City of Yogyakarta, Indonesia and Hanoi Vietnam. Subjects were chosen using snowballing techniques. The result showed there was similar perceptions among respondents in both cities, in terms of access, quantity, and quality of water. All respondents decribed that they have adequate access to water supply, whether provided by the water company or derived from dug well. Repondents’s perceptions showed a degree of satisfaction with the quantity of water but a slight concern of quality.
本研究探讨了日惹和河内城市地区用水者对水的获取、水量、水质和水处理的看法。本研究采用定性和描述性方法。研究对象位于印度尼西亚日惹市和越南河内市。研究对象通过滚雪球技术选出。结果显示,两个城市的受访者在用水的获取、数量和质量方面都有相似的看法。所有受访者都表示,无论是自来水公司提供的自来水还是挖井取水,他们都能获得充足的供水。受访者的看法显示,他们对水量有一定程度的满意,但对水质略有担忧。
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引用次数: 0
Biosynthesis and Characterization of Edible Films from Kepok Banana Peel Starch with a Combination of Glycerol-Sorbitol Plasticizer 使用甘油-山梨醇增塑剂组合从 Kepok 香蕉皮淀粉中生物合成食用薄膜并确定其特性
Pub Date : 2024-04-16 DOI: 10.4028/p-otgy4q
Alvina Lutviyani, E. Sedyadi, I. N. Indrajati
Research on making edible films from kepok banana peels with glycerol-sorbitol plasticizer aims to analyze the mechanical properties and functional groups of edible films from kepok banana peels with a comparison of the concentration of the plasticizer combination of glycerol-sorbitol. This research consisted of 3 stages, namely making kepok banana peel starch, making edible films, and characterizing kepok banana peel starch and edible films. The yield of kepok banana peel starch obtained was 11.94%. Edible film production was carried out with variations in the glycerol-sorbitol concentration ratio of 100:0, 75:25, 50:50, 25:75 and 0:100 on a basis of 40% (w/w) of total starch weight. Functional group analysis of kepok banana peel starch and edible film was carried out with Fourier Transform Infrared (FTIR). Testing the characteristics of the edible film includes thickness, tensile strength, elongation, and Young's modulus. The results showed that edible film was successfully made with mechanical properties that tended to comply with the Japanese Industrial Standard (JIS) 1975 on the parameters of thickness, tensile strength, and young's modulus.
用甘油-山梨醇增塑剂制作可食用的kepok香蕉皮薄膜的研究,旨在通过比较甘油-山梨醇增塑剂组合的浓度,分析可食用的kepok香蕉皮薄膜的机械性能和功能基团。这项研究包括三个阶段,即制作kepok香蕉皮淀粉、制作可食用薄膜和表征kepok香蕉皮淀粉和可食用薄膜。香蕉皮淀粉的产量为 11.94%。以淀粉总重量的 40%(重量比)为基准,甘油与山梨醇的浓度比分别为 100:0、75:25、50:50、25:75 和 0:100。用傅立叶变换红外光谱(FTIR)对克波克香蕉皮淀粉和可食用薄膜进行了官能团分析。测试可食用薄膜的特性包括厚度、拉伸强度、伸长率和杨氏模量。结果表明,成功制成的食用薄膜在厚度、拉伸强度和杨氏模量等参数上的机械性能趋于符合日本工业标准(JIS)1975。
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引用次数: 0
Flowshop Production Scheduling Using the Campbell, Dudek, Smith (CDS), Palmer, and Dannenbring Methods to Minimize the Total Production Time (Case Study: PT. Naturindo Fresh Kulon Progo, Indonesia) 使用坎贝尔、杜德克、史密斯 (CDS)、帕尔默和丹能布林方法进行流水线生产调度,最大限度地缩短总生产时间(案例研究:PT. Naturindo Fresh Kulon Progo,印度尼西亚)
Pub Date : 2024-04-16 DOI: 10.4028/p-ps93tq
Taufik Alfuad, Khusna Dwijayanti
PT. Naturindo Fresh is a company that produces and distributes original Indonesian herbal medicines. The company does not have a planned schedule to minimize the total production time. The production is carried out by considering the products stock and the number of orders from consumers. The employees are free to randomly choose which products will be produced first. The purpose of this research is to determine the job sequence and calculating the total production time (makespan), and identify the sequence that create smallest makespan. The methods used in this research are Campbell, Dudek, & Smith (CDS) method, Palmer method, and Dannenbring method. The calculation results shows that the company's actual scheduling produces a makespan of 30,725.08 minutes. The result of CDS method produces the makespan of 30,634.18 minutes. Palmer's method produces the makespan of 30,743.75 minutes, and the Dannenbring method also yield the makespan of 30,743.75 minutes. In conclusion, the job scheduling with CDS method has the smallest makespan which is recommended to be applied in the company to minimize the total production time.
PT.Naturindo Fresh 是一家生产和销售印尼原产草药的公司。该公司没有计划时间表,以尽量缩短总生产时间。生产是根据产品库存和消费者订单数量进行的。员工可以随机选择先生产哪些产品。本研究的目的是确定工作顺序,计算总生产时间(makespan),并找出产生最小生产时间的顺序。本研究采用的方法有坎贝尔、杜德克和史密斯(CDS)法、帕尔默法和丹能布林法。计算结果显示,该公司的实际排程产生了 30725.08 分钟的生产间隔。CDS 方法的计算结果为 30634.18 分钟。帕尔默方法的计算结果为 30743.75 分钟,丹宁布林方法的计算结果也是 30743.75 分钟。总之,采用 CDS 方法的作业调度具有最小的时间跨度,建议在公司中应用,以最大限度地减少总生产时间。
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引用次数: 0
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