Valeriy V. Dubenskiy, Olga Alexandrova, Ekaterina Muraveva, E. Kuleshova, M. Fadeeva, T. Rusina
Aim: to evaluate the efficiency of post-acne treatment using the combination of trichloroacetic peeling and a hyaluronic acid implant. Peeling with trichloroacetic acid belongs to the category of medium peels that penetrates the epidermis and reaches the basal membrane - the border between the epidermis and the dermis. Sometimes the papillary layer of the dermis is also burned out. Fillers are injectable dermal fillers that are widely used to correct cosmetic defects. The prescribed combination of peeling and hyaluronic acid gives a good therapeutic effect, since trichloacetic acid eliminates persistent defects (dyschromia, scars), creates a uniform color, and hyaluronic acid fills in atrophic changes and moisturizes the skin. Results: we present a clinical case where acne scars were corrected with a course of the systemic retinoids followed by TCA peeling and hyaluronic acid filler. The treatment enables to reduce the size of atrophic scars, makes skin smoother and evens the skin tone. Conclusion: This clinical case can be interesting for dermatologists, since it confirms the efficiency of using hyaluronic acid fillers and TCA peeling in post-acne therapy.
{"title":"TREATMENT OF POSTACNE USING THE COMBINATION OF TRICHLOROACETIC PEELING AND HYALURONIC IMPLANT: A CLINICAL CASE","authors":"Valeriy V. Dubenskiy, Olga Alexandrova, Ekaterina Muraveva, E. Kuleshova, M. Fadeeva, T. Rusina","doi":"10.35630/2023/13/2.412","DOIUrl":"https://doi.org/10.35630/2023/13/2.412","url":null,"abstract":"Aim: to evaluate the efficiency of post-acne treatment using the combination of trichloroacetic peeling and a hyaluronic acid implant. Peeling with trichloroacetic acid belongs to the category of medium peels that penetrates the epidermis and reaches the basal membrane - the border between the epidermis and the dermis. Sometimes the papillary layer of the dermis is also burned out. Fillers are injectable dermal fillers that are widely used to correct cosmetic defects. The prescribed combination of peeling and hyaluronic acid gives a good therapeutic effect, since trichloacetic acid eliminates persistent defects (dyschromia, scars), creates a uniform color, and hyaluronic acid fills in atrophic changes and moisturizes the skin. Results: we present a clinical case where acne scars were corrected with a course of the systemic retinoids followed by TCA peeling and hyaluronic acid filler. The treatment enables to reduce the size of atrophic scars, makes skin smoother and evens the skin tone. Conclusion: This clinical case can be interesting for dermatologists, since it confirms the efficiency of using hyaluronic acid fillers and TCA peeling in post-acne therapy.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49584066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Domenyuk, O. Sumkina, S. Dmitrienko, T. Kochkonyan, V. Konnov, E. Pichugina, A. Arushanyan, O. Ivanyuta, S. Domenyuk
Major research carried out in modern dentistry and maxillofacial surgery is commonly focused on long-term and stable results for implant rehabilitation of jaw defects and deformities in patients with bone and soft tissue losses at the site of planned implantation. Various osteoplastic materials, donor or the patient’s own bone, tissue-engineering and cellular products are common in clinical medicine, since guided regeneration can help not only recover the volume of bone tissue once lost, yet also ensure an outcome acceptable from both functional and aesthetic view. Guided bone regeneration employs methods of regenerative medicine and tissue engineering, with transplantation of native bone tissue and cell transplants, as well as various osteoplastic materials with osteoinductive and osteoconductive properties. In order to compare the structure of intact bone tissue obtained from intraoral and extraoral donor zones, histological and morphometric studies of bone autografts in 4 certified male cadavers with intact dentition were carried out. The results of histological studies in bone tissue autografts from intraoral and extraoral donor zones revealed that the highest density of bone rods could be observed in biopsies taken from the mandible outer oblique line area and chin symphysis. Whereas the lowest rate of the said factor we observed in the biopsies obtained from the iliac crest area. The highest rate of the inter-rod girder space was found in the area of the iliac crest, and the minimal – in biopsies from the parietal bone. The highest bone vascularization level was identified at the iliac crest and the parietal bone, while its lowest levels were seen in biopsies taken from the area of the mandible outer oblique line. The density of cellular elements was found to be highest at the iliac crest. The lowest density level was registered in biopsies from the area of the mandible outer oblique line. The high rates of cellular elements in autografts from the iliac crest area can be accounted for by the predominance of spongy substance over cortical, while in bone biopsies taken from the mandible outer oblique line, chin symphysis, maxillary tuberosity and parietal bone, the share of cellular elements failed to exceed 27% within the total data set. This points at the predominance of cortical rather than spongy substance. In reconstructive bone plastic surgery for augmentation of the maxillary alveolar process and the mandible alveolar part with significant atrophy, it is reasonable to use autogenous transplants taken from intraoral donor zones. The autogenous transplants have cortical morphology and embryological origin similar to the jaw bones. Bone blocks from the donor zones of the mandible outer oblique line, the chin symphysis and the maxillary tuberosity have the highest density of the bone cortical substance and the duly sufficient amount of spongy substance.
{"title":"HISTOLOGICAL AND MORPHOMETRIC STUDIES OF BONE TISSUE AUTOGRAFTS FROM INTRAORAL AND EXTRAORAL DONOR ZONES","authors":"D. Domenyuk, O. Sumkina, S. Dmitrienko, T. Kochkonyan, V. Konnov, E. Pichugina, A. Arushanyan, O. Ivanyuta, S. Domenyuk","doi":"10.35630/2023/13/2.415","DOIUrl":"https://doi.org/10.35630/2023/13/2.415","url":null,"abstract":"Major research carried out in modern dentistry and maxillofacial surgery is commonly focused on long-term and stable results for implant rehabilitation of jaw defects and deformities in patients with bone and soft tissue losses at the site of planned implantation. Various osteoplastic materials, donor or the patient’s own bone, tissue-engineering and cellular products are common in clinical medicine, since guided regeneration can help not only recover the volume of bone tissue once lost, yet also ensure an outcome acceptable from both functional and aesthetic view. Guided bone regeneration employs methods of regenerative medicine and tissue engineering, with transplantation of native bone tissue and cell transplants, as well as various osteoplastic materials with osteoinductive and osteoconductive properties. In order to compare the structure of intact bone tissue obtained from intraoral and extraoral donor zones, histological and morphometric studies of bone autografts in 4 certified male cadavers with intact dentition were carried out. The results of histological studies in bone tissue autografts from intraoral and extraoral donor zones revealed that the highest density of bone rods could be observed in biopsies taken from the mandible outer oblique line area and chin symphysis. Whereas the lowest rate of the said factor we observed in the biopsies obtained from the iliac crest area. The highest rate of the inter-rod girder space was found in the area of the iliac crest, and the minimal – in biopsies from the parietal bone. The highest bone vascularization level was identified at the iliac crest and the parietal bone, while its lowest levels were seen in biopsies taken from the area of the mandible outer oblique line. The density of cellular elements was found to be highest at the iliac crest. The lowest density level was registered in biopsies from the area of the mandible outer oblique line. The high rates of cellular elements in autografts from the iliac crest area can be accounted for by the predominance of spongy substance over cortical, while in bone biopsies taken from the mandible outer oblique line, chin symphysis, maxillary tuberosity and parietal bone, the share of cellular elements failed to exceed 27% within the total data set. This points at the predominance of cortical rather than spongy substance. In reconstructive bone plastic surgery for augmentation of the maxillary alveolar process and the mandible alveolar part with significant atrophy, it is reasonable to use autogenous transplants taken from intraoral donor zones. The autogenous transplants have cortical morphology and embryological origin similar to the jaw bones. Bone blocks from the donor zones of the mandible outer oblique line, the chin symphysis and the maxillary tuberosity have the highest density of the bone cortical substance and the duly sufficient amount of spongy substance.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44425051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kalashnikov, Yu.N. Litun, Yuriy Stavinsky, V. Protsenko, N. Kalinin, Y. Solonitsyn
Relevance: By frequency, tibial bone fractures rank second, accounting for 13% to 21.4% of all musculoskeletal injuries or 64.3%-70% of lower limb bone fractures. The nature of the injury is the result of high-energy trauma and is accompanied by severe soft tissue damage and a comminuted type of fracture. Temporary disability of patients with tibial fractures varies from 8-10 weeks to 5-7 months, and for complex fractures, it can reach 10-12 months. The purpose of the study was to conduct a comparative analysis of the treatment results of patients with tibial bone fractures and to evaluate the effectiveness of different methods of osteosynthesis. Material and methods: Depending on the method of operative treatment, the patients were divided into two groups. The experimental group included 113 patients, mostly with diaphyseal fractures of the tibial bones, who underwent surgery with the use of blocking intramedullary osteosynthesis. The control group consisted of 166 patients with tibial bone fractures who underwent intracortical or trans-cortical osteosynthesis. Results: The use of low-traumatic methods of stable fixation for the patients of the main group, the possibility of early functional rehabilitation, measures to prevent joint contractures since the first days, the possibility of early dosed loading on the operated limb ultimately led to faster healing of tibial fracture and a shorter overall treatment time. In the main group of patients, fusion was observed from 8 to 22 (11.56 ± 2.56) weeks, in the control group - from 12 to 36 (18.68 ± 4.70) weeks. The general treatment period for patients in the main group ranged from 8 to 22 (14.44 ± 2.85) weeks, while for the control group, it was from 13 to 43 (21.23 ± 5.38) weeks. Conclusion: The use of blocking intramedullary osteosynthesis has demonstrated its high effectiveness in the surgical treatment of patients with metadiaphyseal fractures of the tibia, allowing for positive treatment results in 96.66% of patients. The advantage of blocking intramedullary osteosynthesis is the biomechanically justified high stability of fixation and minimal invasiveness, which enables early mobilization in patients with fractures of the tibia bones (FTB) often experience a reduced quality of life and temporary disability, which can last from 8-10 weeks to 5-7 months or even up to 10-12 months for complex fractures. FTBs account for 13%-21.4% of all musculoskeletal injuries or 64.3%-70% of all lower limb fractures. The frequency of diaphyseal tibia bone fractures is 26-32 cases per 100,000 population. The injuries are typically the result of high-energy trauma and are often accompanied by severe soft tissue damage and comminuted fractures. The use of blocking intramedullary osteosynthesis has been shown to be highly effective in the surgical treatment of patients with meta-diaphyseal fractures of the tibia bones, with positive treatment outcomes in 96.66% of patients, providing biomechanically justified high
{"title":"ANALYSIS OF SURGICAL TREATMENT RESULTS IN PATIENTS WITH FRACTURES OF THE TIBIAL BONES","authors":"A. Kalashnikov, Yu.N. Litun, Yuriy Stavinsky, V. Protsenko, N. Kalinin, Y. Solonitsyn","doi":"10.35630/2023/13/2.410","DOIUrl":"https://doi.org/10.35630/2023/13/2.410","url":null,"abstract":"Relevance: By frequency, tibial bone fractures rank second, accounting for 13% to 21.4% of all musculoskeletal injuries or 64.3%-70% of lower limb bone fractures. The nature of the injury is the result of high-energy trauma and is accompanied by severe soft tissue damage and a comminuted type of fracture. Temporary disability of patients with tibial fractures varies from 8-10 weeks to 5-7 months, and for complex fractures, it can reach 10-12 months. The purpose of the study was to conduct a comparative analysis of the treatment results of patients with tibial bone fractures and to evaluate the effectiveness of different methods of osteosynthesis. Material and methods: Depending on the method of operative treatment, the patients were divided into two groups. The experimental group included 113 patients, mostly with diaphyseal fractures of the tibial bones, who underwent surgery with the use of blocking intramedullary osteosynthesis. The control group consisted of 166 patients with tibial bone fractures who underwent intracortical or trans-cortical osteosynthesis. Results: The use of low-traumatic methods of stable fixation for the patients of the main group, the possibility of early functional rehabilitation, measures to prevent joint contractures since the first days, the possibility of early dosed loading on the operated limb ultimately led to faster healing of tibial fracture and a shorter overall treatment time. In the main group of patients, fusion was observed from 8 to 22 (11.56 ± 2.56) weeks, in the control group - from 12 to 36 (18.68 ± 4.70) weeks. The general treatment period for patients in the main group ranged from 8 to 22 (14.44 ± 2.85) weeks, while for the control group, it was from 13 to 43 (21.23 ± 5.38) weeks. Conclusion: The use of blocking intramedullary osteosynthesis has demonstrated its high effectiveness in the surgical treatment of patients with metadiaphyseal fractures of the tibia, allowing for positive treatment results in 96.66% of patients. The advantage of blocking intramedullary osteosynthesis is the biomechanically justified high stability of fixation and minimal invasiveness, which enables early mobilization in patients with fractures of the tibia bones (FTB) often experience a reduced quality of life and temporary disability, which can last from 8-10 weeks to 5-7 months or even up to 10-12 months for complex fractures. FTBs account for 13%-21.4% of all musculoskeletal injuries or 64.3%-70% of all lower limb fractures. The frequency of diaphyseal tibia bone fractures is 26-32 cases per 100,000 population. The injuries are typically the result of high-energy trauma and are often accompanied by severe soft tissue damage and comminuted fractures. The use of blocking intramedullary osteosynthesis has been shown to be highly effective in the surgical treatment of patients with meta-diaphyseal fractures of the tibia bones, with positive treatment outcomes in 96.66% of patients, providing biomechanically justified high ","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45086529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Germanova, Yuriy V. Shchukin, A. Usenova, Luisa Koonts, Irina Buklesheva, A. Germanov
Prototype models of intra-arterial circulation is one of the priority aims of experimental cardiology, as well as for the study of atherosclerosis. Purpose: To study the features of intra-arterial hemodynamics in the area ofatheroma of the artery in physical modeling. Materials and methods: We used an original "Device for modeling intra-arterial circulation". The main parts of the model: glass rotameter tube in the form of a truncated cylinder, inlet and outlet ends of which are fixed with elastic plastic tubes connected to an electric water pump immersed in a container with glycerol solution. Inside the rotameter, using a fitting from the inlet, it is possible to install a pressure sensor that transfers data to the oscilloscope; indicators - a silk thread or dye - ink. The variable pump mode allowed us to simulate a regular heart rhythm, extrasystole (ES) and atrial fibrillation (AF). Results: In the first post-extrasystolic wave, a turbulent fluid flow formed after the plaque, standing waves and waves reflected from the walls of the rotameter were observed; the sensor registered an increase in pressure 1,6 times more compared with a regular heart rate wave. The marginal plaque zones along and against the fluid flow, especially the areas bordering the intact part of the arterial vessel, underwent the main mechanical impact. The same patterns were observed in AF with a maximum duration of a pause between pulse waves of ≥1,5 s. Conclusions: Heart arrhythmias play an important role in the intra-arterial hemodynamics changes and are the part of the pathophysiological changes in the arteries in atherosclerosis. The main danger is not the ES itself, but by the first post-extrasystolic contraction or the first pulse wave after a long pause between ventricular contractions in AF.
{"title":"ATHEROMA PROGRESSION: PHYSICAL MODELING IN EXPERIMENTAL CARDIOLOGY","authors":"O. Germanova, Yuriy V. Shchukin, A. Usenova, Luisa Koonts, Irina Buklesheva, A. Germanov","doi":"10.35630/2023/13/2.408","DOIUrl":"https://doi.org/10.35630/2023/13/2.408","url":null,"abstract":"Prototype models of intra-arterial circulation is one of the priority aims of experimental cardiology, as well as for the study of atherosclerosis. Purpose: To study the features of intra-arterial hemodynamics in the area ofatheroma of the artery in physical modeling. Materials and methods: We used an original \"Device for modeling intra-arterial circulation\". The main parts of the model: glass rotameter tube in the form of a truncated cylinder, inlet and outlet ends of which are fixed with elastic plastic tubes connected to an electric water pump immersed in a container with glycerol solution. Inside the rotameter, using a fitting from the inlet, it is possible to install a pressure sensor that transfers data to the oscilloscope; indicators - a silk thread or dye - ink. The variable pump mode allowed us to simulate a regular heart rhythm, extrasystole (ES) and atrial fibrillation (AF). Results: In the first post-extrasystolic wave, a turbulent fluid flow formed after the plaque, standing waves and waves reflected from the walls of the rotameter were observed; the sensor registered an increase in pressure 1,6 times more compared with a regular heart rate wave. The marginal plaque zones along and against the fluid flow, especially the areas bordering the intact part of the arterial vessel, underwent the main mechanical impact. The same patterns were observed in AF with a maximum duration of a pause between pulse waves of ≥1,5 s. Conclusions: Heart arrhythmias play an important role in the intra-arterial hemodynamics changes and are the part of the pathophysiological changes in the arteries in atherosclerosis. The main danger is not the ES itself, but by the first post-extrasystolic contraction or the first pulse wave after a long pause between ventricular contractions in AF.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49120227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the work is to identify the most common complications after COVID–19 and to develop a system of step-by-step rehabilitation of patients using modern medical equipment. The research program is based on the analysis of data from a sociological survey of 792 respondents aged 18 to 76 years, whose average age was 29 ± 1.8 years, while the proportion of women was 70.8%. The following methods are used in the work: bibliographic, analytical, mathematical-statistical, sociological (questionnaire). Relative extensive indicators are used in data processing and presentation. In the course of the study, complications that were most pronounced in patients after a coronavirus infection were studied; an analysis of effective methods for their prevention was carried out; the most effective methods of rehabilitation based on the stages of patient recovery were developed and proposed. As a result of the work carried out, a comprehensive method of restorative therapy of patients is proposed, depending on their functional capabilities and the medical rehabilitation equipment available at the disposal of postcovid centers. It has been established that effectively staged post COVID-19 rehabilitation carried out in a specialized rehabilitation center enables to improve the patients' quality of life, restore physical activity and mental health, reduce the risk of comorbidities, and mortality associated with post-COVID complications.
{"title":"MEDICAL AND ORGANIZATIONAL ASPECTS OF ACTIVITIES AND EQUIPMENT FOR A POST-COVID REHABILITATION CENTER","authors":"A. Breusov, Ali Nasibov, Dmitrii Breusov","doi":"10.35630/2023/13/2.220","DOIUrl":"https://doi.org/10.35630/2023/13/2.220","url":null,"abstract":"The aim of the work is to identify the most common complications after COVID–19 and to develop a system of step-by-step rehabilitation of patients using modern medical equipment. The research program is based on the analysis of data from a sociological survey of 792 respondents aged 18 to 76 years, whose average age was 29 ± 1.8 years, while the proportion of women was 70.8%. The following methods are used in the work: bibliographic, analytical, mathematical-statistical, sociological (questionnaire). Relative extensive indicators are used in data processing and presentation. In the course of the study, complications that were most pronounced in patients after a coronavirus infection were studied; an analysis of effective methods for their prevention was carried out; the most effective methods of rehabilitation based on the stages of patient recovery were developed and proposed. As a result of the work carried out, a comprehensive method of restorative therapy of patients is proposed, depending on their functional capabilities and the medical rehabilitation equipment available at the disposal of postcovid centers. It has been established that effectively staged post COVID-19 rehabilitation carried out in a specialized rehabilitation center enables to improve the patients' quality of life, restore physical activity and mental health, reduce the risk of comorbidities, and mortality associated with post-COVID complications.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43624904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Gumenyuk, D. Ushmarov, A. Gumenyuk, O. Alukhanyan, E. Gladky, O. Shokel, D. Domenyuk
One of the priorities of modern medicine is the development of biomaterials for tissue engineering, transplantation and vascular surgery. Such materials should facilitate the regeneration of damaged body organs and tissues. The problem of regeneration of wound lesions affecting various skin and soft tissues is related to a high rate of secondary infection, deep metabolic shifts in the conditions of severe inflammations, activated oxygen-independent phagocytosis and intensified free-radical response. In patients with wounds of various etiologies, modern clinical practice widely employs numerous wound dressings, where properties are specified in advance according to the stage the wound is going through. The principle of a wound coating is the provision of a moist abacterial environment, which is optimal for accelerated healing. The subjects of our experimental studies were 45 white laboratory rats (males, outbred, each weighing 250-300 g) with soft tissue wounds developed by a specifically designed method. As materials for wound treatment we used chitosan-based multilayer wound dressings of different structure and porosity degree. They were introduced into simulated wounds in the back area between the shoulder blades in rats. The experimental part of the study focused on the sorption capacity of the wound exudate obtained after extraction and weighing of the samples within the control time. The laboratory part of the experiment involved studying the sorption capacity of wound dressing samples in relation to distilled water and blood serum. The morphological assessment of the dressing samples surface was performed on a Helios NanoLab 600electron-ion scanning microscope. It was observed that chitosan-based multilayer wound dressings, had different morphological parameters and molecular structure as well as high sorption activity. Chitosan samples with a so-called loose structure and high porosity should be used in a clean (aseptic) wound at the initial stages of treatment, with no inflammation, where initially high adhesion to surrounding tissues is required, thus, ensuring tightness and keeping a blood clot within the wound. Chitosan samples with a tight-packed structure and a smaller diameter of pores showed good results in purulent inflammation (exudative phase) with a large amount of wound exudate. Due to its dense outer layer, their structure is capable of retaining the skeleton functions for a long time, thus offering effective drainage of the wound.
{"title":"MODERN CHITOSAN-BASED WOUND DRESSINGS IN LOCAL WOUND TREATMENT: PRECLINICAL STUDIES","authors":"S. Gumenyuk, D. Ushmarov, A. Gumenyuk, O. Alukhanyan, E. Gladky, O. Shokel, D. Domenyuk","doi":"10.35630/2023/13/2.411","DOIUrl":"https://doi.org/10.35630/2023/13/2.411","url":null,"abstract":"One of the priorities of modern medicine is the development of biomaterials for tissue engineering, transplantation and vascular surgery. Such materials should facilitate the regeneration of damaged body organs and tissues. The problem of regeneration of wound lesions affecting various skin and soft tissues is related to a high rate of secondary infection, deep metabolic shifts in the conditions of severe inflammations, activated oxygen-independent phagocytosis and intensified free-radical response. In patients with wounds of various etiologies, modern clinical practice widely employs numerous wound dressings, where properties are specified in advance according to the stage the wound is going through. The principle of a wound coating is the provision of a moist abacterial environment, which is optimal for accelerated healing. The subjects of our experimental studies were 45 white laboratory rats (males, outbred, each weighing 250-300 g) with soft tissue wounds developed by a specifically designed method. As materials for wound treatment we used chitosan-based multilayer wound dressings of different structure and porosity degree. They were introduced into simulated wounds in the back area between the shoulder blades in rats. The experimental part of the study focused on the sorption capacity of the wound exudate obtained after extraction and weighing of the samples within the control time. The laboratory part of the experiment involved studying the sorption capacity of wound dressing samples in relation to distilled water and blood serum. The morphological assessment of the dressing samples surface was performed on a Helios NanoLab 600electron-ion scanning microscope. It was observed that chitosan-based multilayer wound dressings, had different morphological parameters and molecular structure as well as high sorption activity. Chitosan samples with a so-called loose structure and high porosity should be used in a clean (aseptic) wound at the initial stages of treatment, with no inflammation, where initially high adhesion to surrounding tissues is required, thus, ensuring tightness and keeping a blood clot within the wound. Chitosan samples with a tight-packed structure and a smaller diameter of pores showed good results in purulent inflammation (exudative phase) with a large amount of wound exudate. Due to its dense outer layer, their structure is capable of retaining the skeleton functions for a long time, thus offering effective drainage of the wound.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42007126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Barinov, Andrey Barinov, S. Voyevodina, Sergey Dzhuvalyakov, I. Osipova, R. Kalinin, O. Romanova
The aim of the study is to analyze treatment and diagnostic errors made by emergency medical services personnel during hospitalization of patients. Materials and Methods: The analysis was made based on 412 report sheets to run sheets, taken at one EMS substation for one month. The sample included only report sheets for orders carried out by EMS feldshers. Analyzed materials showed that 42 report sheets contain defects in filling out the documentation: for example, 3 of them did not indicate a referral diagnosis of the EMS team, and 39 – final diagnosis of the hospital, and, therefore, they cannot be included in the statistical data. Analysis of the remaining 370 report sheets showed that in 60 cases there was an overdiagnosis of the disease, and in 31 cases the diagnosis was incorrect. Conclusion: From the analyzed materials, it is possible to identify the main treatment and diagnostic errors in the work of the EMS in cases of patient hospitalization: Incorrect tactics of managing patients at the prehospital stage due to overestimation/underestimation of symptoms, non-core hospitalization or hospitalization in a non-core hospital due to overestimation/underestimation of symptoms; replacement of a nosological unit with its symptoms or complications.
{"title":"TREATMENT AND DIAGNOSTIC ERRORS MADE BY EMERGENCY MEDICAL SERVICES PERSONNEL DURING HOSPITALIZATION OF PATIENTS","authors":"E. Barinov, Andrey Barinov, S. Voyevodina, Sergey Dzhuvalyakov, I. Osipova, R. Kalinin, O. Romanova","doi":"10.35630/2023/13/2.404","DOIUrl":"https://doi.org/10.35630/2023/13/2.404","url":null,"abstract":"The aim of the study is to analyze treatment and diagnostic errors made by emergency medical services personnel during hospitalization of patients. Materials and Methods: The analysis was made based on 412 report sheets to run sheets, taken at one EMS substation for one month. The sample included only report sheets for orders carried out by EMS feldshers. Analyzed materials showed that 42 report sheets contain defects in filling out the documentation: for example, 3 of them did not indicate a referral diagnosis of the EMS team, and 39 – final diagnosis of the hospital, and, therefore, they cannot be included in the statistical data. Analysis of the remaining 370 report sheets showed that in 60 cases there was an overdiagnosis of the disease, and in 31 cases the diagnosis was incorrect. Conclusion: From the analyzed materials, it is possible to identify the main treatment and diagnostic errors in the work of the EMS in cases of patient hospitalization: Incorrect tactics of managing patients at the prehospital stage due to overestimation/underestimation of symptoms, non-core hospitalization or hospitalization in a non-core hospital due to overestimation/underestimation of symptoms; replacement of a nosological unit with its symptoms or complications.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46890224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The article presents results of a program of psychological support provided to medical residents. The program was implemented at Astrakhan Medical University (Astrakhan, Russia) in February 2023. This program was aimed at psychological correction of communicative skills and empathic abilities, as professionally important qualities of a medical professional. 38 residents of the specialty Infectious diseases were involved in the program. We developed and implemented the program of psychological support, which consists of four stages: 1) psychological diagnosis; 2) theoretical block; 3) psychological correction in form of individual and group trainings on empathy level and communication skills (conversation, cognitive-behavioral psychotherapy, transactional analysis, Ericksonian hypnosis techniques); 4) re-diagnosis in order to assess psychological indicators. Mastering the techniques of managing the emotional state positively influences the psychological well-being of medical residents. Our program made it possible to improve the soft competencies required for medical professionals.
{"title":"PROGRAM OF PSYCHOLOGICAL SUPPORT FOR DEVELOPING ESSENTIAL QUALITIES A DOCTOR SHOULD POSSESS","authors":"Milana Yarakhmedova, Albina Shkhalakhova, Larisa Busurina, Aliya Abdullaeva","doi":"10.35630/2023/13/2.403","DOIUrl":"https://doi.org/10.35630/2023/13/2.403","url":null,"abstract":"The article presents results of a program of psychological support provided to medical residents. The program was implemented at Astrakhan Medical University (Astrakhan, Russia) in February 2023. This program was aimed at psychological correction of communicative skills and empathic abilities, as professionally important qualities of a medical professional. 38 residents of the specialty Infectious diseases were involved in the program. We developed and implemented the program of psychological support, which consists of four stages: 1) psychological diagnosis; 2) theoretical block; 3) psychological correction in form of individual and group trainings on empathy level and communication skills (conversation, cognitive-behavioral psychotherapy, transactional analysis, Ericksonian hypnosis techniques); 4) re-diagnosis in order to assess psychological indicators. Mastering the techniques of managing the emotional state positively influences the psychological well-being of medical residents. Our program made it possible to improve the soft competencies required for medical professionals.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134968055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In-depth interviews were conducted with 83 residents of the dental profile of graduates of medical universities in Moscow, Krasnoyarsk and Ufa. As a result of studying the opinions of graduates of medical universities, certain difficulties were identified in the prospective development of professional growth and the passing the accreditation procedure. The dissatisfaction of the respondents was associated with the imperfection of the system of training and motivation of graduates to improve their professional skills and competencies. In this regard, measures are needed to improve the quality of training of medical personnel, as well as ways to improve and increase the availability of quality medical education.
{"title":"QUALITY OF HIGH MEDICAL EDUCATION IN RUSSIA","authors":"Ksenia Zavadich, Sergey Averyanov, Julia Afanasyeva, Sergey Lazarev, Ludmila Startseva, Ilgiz Iskhakov","doi":"10.35630/2023/13/2.402","DOIUrl":"https://doi.org/10.35630/2023/13/2.402","url":null,"abstract":"In-depth interviews were conducted with 83 residents of the dental profile of graduates of medical universities in Moscow, Krasnoyarsk and Ufa. As a result of studying the opinions of graduates of medical universities, certain difficulties were identified in the prospective development of professional growth and the passing the accreditation procedure. The dissatisfaction of the respondents was associated with the imperfection of the system of training and motivation of graduates to improve their professional skills and competencies. In this regard, measures are needed to improve the quality of training of medical personnel, as well as ways to improve and increase the availability of quality medical education.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135111025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Osadchuk, Oleh Kostogryz, V. Protsenko, Y. Solonitsyn
The study presents the experience of surgical treatment for deforming osteoarthritis of the knee joint of II-III stage, with axial deformations in 75 patients. Supracondylar varus resection osteotomies of the femur and supratuberous valgus osteotomies of the tibia were performed depending on the knee joint deformities. The results of these surgical interventions were evaluated according to the methods developed in our clinic. Good results were obtained in 74% of cases, satisfactory - in 26% of cases.
{"title":"RECONSTRUCTIVE SURGERY IN GONARTHROSIS WITH AXIAL DEFORMATIONS OF KNEE JOINT","authors":"T. Osadchuk, Oleh Kostogryz, V. Protsenko, Y. Solonitsyn","doi":"10.35630/2023/13/2.409","DOIUrl":"https://doi.org/10.35630/2023/13/2.409","url":null,"abstract":"The study presents the experience of surgical treatment for deforming osteoarthritis of the knee joint of II-III stage, with axial deformations in 75 patients. Supracondylar varus resection osteotomies of the femur and supratuberous valgus osteotomies of the tibia were performed depending on the knee joint deformities. The results of these surgical interventions were evaluated according to the methods developed in our clinic. Good results were obtained in 74% of cases, satisfactory - in 26% of cases.","PeriodicalId":51770,"journal":{"name":"Archiv EuroMedica","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49111985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：