Laila Lahrizi, F. Errachidi, Houria Nekhla, L. Ghadraoui
The traditional knowledge of Ajuga iva (L.) Schreb. used in Moroccan folk medicine may provide insight into its utilities for further in vitro and in vivo evaluation. The present work was undertaken with a view to highlighting one of the medicinal plants ''musk herb'', which has a wide geographical distribution in Morocco and which would be of great added value for the Moroccan pharmacopeia in general. An ethnopharmacological survey was conducted to interview a total of 207 informants, a questionnaire targeted the population of Fez-Meknes region. The interviewed people about the utility of A. iva confirmed the effectiveness of this plant in the treatment of numerous illnesses especially those affected digestive system (40.99%), headache (14.07%), fever (11.85%), and other pathologies represented 16.04%. The most part used is the leaves (48.30%) followed by the whole plant (43.47%). The present survey displays the importance of A. iva in the medical culture of Fez-Meknes population for the primary and secondary prevention of different disorders. Future mechanistic studies, as well as clinical trials, are needed to evaluate the safety and efficacy of this medicinal plant according to its ethnopharmacological uses.
{"title":"Unraveling Traditional Knowledge of Ajuga iva (L.) Schreb. Used in the Fez-Meknes Area in Morocco","authors":"Laila Lahrizi, F. Errachidi, Houria Nekhla, L. Ghadraoui","doi":"10.18502/tim.v7i4.11491","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11491","url":null,"abstract":"The traditional knowledge of Ajuga iva (L.) Schreb. used in Moroccan folk medicine may provide insight into its utilities for further in vitro and in vivo evaluation. The present work was undertaken with a view to highlighting one of the medicinal plants ''musk herb'', which has a wide geographical distribution in Morocco and which would be of great added value for the Moroccan pharmacopeia in general. An ethnopharmacological survey was conducted to interview a total of 207 informants, a questionnaire targeted the population of Fez-Meknes region. The interviewed people about the utility of A. iva confirmed the effectiveness of this plant in the treatment of numerous illnesses especially those affected digestive system (40.99%), headache (14.07%), fever (11.85%), and other pathologies represented 16.04%. The most part used is the leaves (48.30%) followed by the whole plant (43.47%). The present survey displays the importance of A. iva in the medical culture of Fez-Meknes population for the primary and secondary prevention of different disorders. Future mechanistic studies, as well as clinical trials, are needed to evaluate the safety and efficacy of this medicinal plant according to its ethnopharmacological uses.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43684669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Sanaie, A. Zeinalhajlou, Z. Yousefi, Alireza Bagherzadeh-karimi, Fatemeh Jahanjoo, Hosein Matlabi, Mostafa Araj-khodaei
The quality of sleep changes with age and a reduction in sleep duration is observed in the elderly. Mizaj (temperament) is a fundamental theory in traditional Persian medicine. It is defined as all sides of personality describing a person’s morphological, psychological, and physiological situations. Although the evidence showed that temperament and sleep quality are related, no research has evaluated this issue statistically so far. Hence, this study aimed to evaluate the correlation between sleep quality and temperament. This cross-sectional study included 1,359 elderly people (aged 60) in Tabriz, Iran in 2019. An interviewer accomplished the Tabriz Older People Survey (TOPS), Temperament and Sleep Quality Test, and Pittsburgh Sleep Quality Index (PSQI). A p value less than 0.05 was considered as significant. Our findings indicated that there was a significant relationship between global PSQI and wet temperament (p value = 0.036). In addition, hot-cold temperament was statistically related to demographical items like gender, marital status, and occupational status (p value ≤ 0.05). A similar statistically significant relationship was also seen for wet-dry temperament (p value ≤ 0.05). Moreover, the global PSQI score in female and illiterates subjects and those who lived in detached houses was high, meaning that the sleep quality was poor in these groups. According to our findings, Mizaj affects the quality of sleep in older adults. Also, living conditions of the elderly, such as gender, type of residence, level of education, and job, affect the Mizaj of the elderly people.
睡眠质量随着年龄的增长而变化，在老年人中观察到睡眠时间的减少。Mizaj(气质)是传统波斯医学的一个基本理论。它被定义为描述一个人的形态、心理和生理状况的人格的各个方面。尽管有证据表明气质和睡眠质量是相关的，但迄今为止还没有研究对这一问题进行统计评估。因此，本研究旨在评估睡眠质量与气质之间的相关性。这项横断面研究包括2019年伊朗大不里士的1359名老年人(60岁)。访谈者完成大不里士老年人调查(TOPS)、气质与睡眠质量测试(Temperament and Sleep Quality Test)、匹兹堡睡眠质量指数(PSQI)。p值小于0.05为显著性。我们的研究结果表明，全球PSQI与湿气质之间存在显著关系(p值= 0.036)。此外，冷热气质与性别、婚姻状况、职业状况等人口学项目有统计学相关性(p值≤0.05)。干湿气质也有类似的统计学意义(p值≤0.05)。此外，女性和文盲以及独居者的全球PSQI得分较高，这意味着这些群体的睡眠质量较差。根据我们的发现，米扎伊会影响老年人的睡眠质量。此外，老年人的生活条件，如性别、居住类型、教育水平、职业等，也会影响老年人的Mizaj。
{"title":"Evaluating the Relationship between Sleep Quality and Temperament in Older Adults: Data from TOPS (Tabriz Older People Survey)","authors":"S. Sanaie, A. Zeinalhajlou, Z. Yousefi, Alireza Bagherzadeh-karimi, Fatemeh Jahanjoo, Hosein Matlabi, Mostafa Araj-khodaei","doi":"10.18502/tim.v7i4.11486","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11486","url":null,"abstract":"The quality of sleep changes with age and a reduction in sleep duration is observed in the elderly. Mizaj (temperament) is a fundamental theory in traditional Persian medicine. It is defined as all sides of personality describing a person’s morphological, psychological, and physiological situations. Although the evidence showed that temperament and sleep quality are related, no research has evaluated this issue statistically so far. Hence, this study aimed to evaluate the correlation between sleep quality and temperament. This cross-sectional study included 1,359 elderly people (aged 60) in Tabriz, Iran in 2019. An interviewer accomplished the Tabriz Older People Survey (TOPS), Temperament and Sleep Quality Test, and Pittsburgh Sleep Quality Index (PSQI). A p value less than 0.05 was considered as significant. Our findings indicated that there was a significant relationship between global PSQI and wet temperament (p value = 0.036). In addition, hot-cold temperament was statistically related to demographical items like gender, marital status, and occupational status (p value ≤ 0.05). A similar statistically significant relationship was also seen for wet-dry temperament (p value ≤ 0.05). Moreover, the global PSQI score in female and illiterates subjects and those who lived in detached houses was high, meaning that the sleep quality was poor in these groups. According to our findings, Mizaj affects the quality of sleep in older adults. Also, living conditions of the elderly, such as gender, type of residence, level of education, and job, affect the Mizaj of the elderly people.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42968685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Obiang, T. Ndong Mba, Rick Léonid Ngoua Meye Misso, Juliette Ornely Orango Bourdette, J. Privat Ondo, Guy Roger Ndong Atome, Louis-Clément Obame Engonga, E. Emvo
The purpose of this work was to develop ethnopharmacological and biological studies of plants used in traditional medicine for the treatment of diarrheal diseases. This study results in scientific data that validates the uses of these plants in traditional medicine. Firstly, ethnopharmacological surveys were conducted with a few traditional healers from the provinces of Estuaire, Haut Ogooué and Woleu-Ntem in Gabon. Next, ethnobotanical data such as percentage of families, species, routes of administration, methods of preparation, parts used and number of plant names were analyzed and summarized. Finally, the antibacterial activities of some plants have been evaluated by diffusion and microdilution methods. Thirty-four (34) traditional healers were interviewed. A total of 90 plant species were identified during this study. They belong to 44 families, the most represented were Leguminoseae (13.33%), Apocynaceae (7.78%), Annonaceae (5.55%), Euphorbiaceae (4.44%) and Anacardiaceae (4.44%). Trees were used more (44.44%) than shrubs (32.22%), herbaceous plants (16.67%) and lianas (6.67%). The drug administration was mainly oral (84.62%) and by the anal route. Decoction and maceration were the two most used methods of preparation. Among identified plants, twenty-seven (27) plant extracts were subjected to microbiological analyzes. Plant extracts tested were active on Gram-negative and Gram-positive bacteria. Cola nitida extracts gave the best antibacterial activity against Enterococcus faecalis 103907 CIP. This study identified 90 antidiarrheal plant species and clearly shows the antimicrobial potential of several medicinal species.
{"title":"Ethnopharmacological Study and Antibacterial Activities of Some Plants Used in Traditional Medicine for the Treatment of Diarrheal Diseases in Gabon","authors":"C. Obiang, T. Ndong Mba, Rick Léonid Ngoua Meye Misso, Juliette Ornely Orango Bourdette, J. Privat Ondo, Guy Roger Ndong Atome, Louis-Clément Obame Engonga, E. Emvo","doi":"10.18502/tim.v7i4.11489","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11489","url":null,"abstract":"The purpose of this work was to develop ethnopharmacological and biological studies of plants used in traditional medicine for the treatment of diarrheal diseases. This study results in scientific data that validates the uses of these plants in traditional medicine. Firstly, ethnopharmacological surveys were conducted with a few traditional healers from the provinces of Estuaire, Haut Ogooué and Woleu-Ntem in Gabon. Next, ethnobotanical data such as percentage of families, species, routes of administration, methods of preparation, parts used and number of plant names were analyzed and summarized. Finally, the antibacterial activities of some plants have been evaluated by diffusion and microdilution methods. Thirty-four (34) traditional healers were interviewed. A total of 90 plant species were identified during this study. They belong to 44 families, the most represented were Leguminoseae (13.33%), Apocynaceae (7.78%), Annonaceae (5.55%), Euphorbiaceae (4.44%) and Anacardiaceae (4.44%). Trees were used more (44.44%) than shrubs (32.22%), herbaceous plants (16.67%) and lianas (6.67%). The drug administration was mainly oral (84.62%) and by the anal route. Decoction and maceration were the two most used methods of preparation. Among identified plants, twenty-seven (27) plant extracts were subjected to microbiological analyzes. Plant extracts tested were active on Gram-negative and Gram-positive bacteria. Cola nitida extracts gave the best antibacterial activity against Enterococcus faecalis 103907 CIP. This study identified 90 antidiarrheal plant species and clearly shows the antimicrobial potential of several medicinal species.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48142611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahsa Rostami Chijan, Mehdi Salehi, Mohadeseh Ostovar, Elham Haghjoo, Massih Sedigh Rahimabadi, M. H. Hashempur
Complementary and alternative medicine (CAM) has shown increasing acceptance, popularity, and use all around the world. The International Complementary and Alternative Medicine Questionnaire (I-CAM-Q) was developed to be a standard research instrument for achieving more reliable data and enabling researchers for comparing multiple studies on CAM use. This study aimed to provide a Persian translation of I-CAM-Q that also was adapted according to Iranian culture. The I-CAM-Q was translated and back-translated to Persian by a team of 2 translators and 2 traditional Persian medicine specialists. Then an internet-based specialist survey and an experts’ panel using the DELPHI method were done to perform cross-cultural adaptation. The feasibility study of the Iranian version of I-CAM-Q (i.e., I-CAM-IR) was tested upon adult population, the final changes were done to I-CAM-IR and data were gathered from 301 hypertensive patients. The related specific words such as traditional Persian medicine and “Attar” (herbalist) were added to the questionnaire for a more precise local adaptation. Meanwhile, some structural changes were made in the first two pages of the original I-CAM-Q and the questions about disclosure were added to it. This questionnaire was easily accepted by most patients during the interview. Generally, 72.4% of our hypertensive participants used CAM but only 41.8% of them disclosed this to their physicians. I-CAM-Q is a standard questionnaire that needs to be adapted to non-English speaking countries. Generally, in this study the useage of CAM among people with hypertention was high. Therefore, it is emphesised that physisians should have adequate knowledge about it. Meanwhile, conducting multicentral researches in this field will provide the basis for accumulative data about CAM use in Iran.
{"title":"The I-CAM-IR: Persian Translation, Cross-Cultural Adaptation and Revised Version of the I-CAM-Q","authors":"Mahsa Rostami Chijan, Mehdi Salehi, Mohadeseh Ostovar, Elham Haghjoo, Massih Sedigh Rahimabadi, M. H. Hashempur","doi":"10.18502/tim.v7i4.11494","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11494","url":null,"abstract":"Complementary and alternative medicine (CAM) has shown increasing acceptance, popularity, and use all around the world. The International Complementary and Alternative Medicine Questionnaire (I-CAM-Q) was developed to be a standard research instrument for achieving more reliable data and enabling researchers for comparing multiple studies on CAM use. This study aimed to provide a Persian translation of I-CAM-Q that also was adapted according to Iranian culture. The I-CAM-Q was translated and back-translated to Persian by a team of 2 translators and 2 traditional Persian medicine specialists. Then an internet-based specialist survey and an experts’ panel using the DELPHI method were done to perform cross-cultural adaptation. The feasibility study of the Iranian version of I-CAM-Q (i.e., I-CAM-IR) was tested upon adult population, the final changes were done to I-CAM-IR and data were gathered from 301 hypertensive patients. The related specific words such as traditional Persian medicine and “Attar” (herbalist) were added to the questionnaire for a more precise local adaptation. Meanwhile, some structural changes were made in the first two pages of the original I-CAM-Q and the questions about disclosure were added to it. This questionnaire was easily accepted by most patients during the interview. Generally, 72.4% of our hypertensive participants used CAM but only 41.8% of them disclosed this to their physicians. I-CAM-Q is a standard questionnaire that needs to be adapted to non-English speaking countries. Generally, in this study the useage of CAM among people with hypertention was high. Therefore, it is emphesised that physisians should have adequate knowledge about it. Meanwhile, conducting multicentral researches in this field will provide the basis for accumulative data about CAM use in Iran.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44334594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nematollah Masoudi, Z. Niktabe, M. Tabarrai, A. Masoudi, F. Ghorat, Fatemeh Moradi, A. Abbassian
Urinary Incontinence (UI) is a significant reason for the decline in women's quality of life. The unexpected occurrence of UI and its high costs around the world are evident. Numerous methods are used for the management of UI; however, there is no worldwide agreement on any of these methods. Traditional medicines are a source of human medical experiences and this study is a review on the books of the most famous Persian medicine (PM) physician, Avicenna, to find about his approach to UI. Keywords such as: "female urinary incontinence", "lifestyle", and “nutrition” were selected. As a library research, Avicenna’s (980- 1037 AD) "the Canon of Medicine" (Al-Qanun Fi al-Tibb), was reviewed and coded. Some other PM famous books like "the Great Continens" (Al-Hawi fi Al-Tibb) of Rhazes (865- 925 AD) and "The Comprehensive Book on Medicine" (Al-Shamil fi Al-Sana'a Al-Tibbiya) of Ibn al-Nafis al-Qarshi (1213- 1288 AD) were used as a help to interpret the codes just in case it was required. Modern literature was searched with the same keywords at electronic databases such as Google Scholar, PubMed, and Magiran. Finally, the results were compared. Recent studies care on conservative and lifestyle management in the treatment of UI. In PM, principles of lifestyle management (Setteh-e-zarurieh) is one of the main characteristics of prevention and treatment with six essential principles including weather, eating and drinking, sleep and wakefulness, movement and rest, evacuation and retention, and psychological and mental reactions. In healthy people, these six axes are designed by temperament and personal characteristics. In this manuscript, we discussed five mentioned subtypes. These managements are appropriate for designing various pieces of clinical trials to survey their effects on female UI.
尿失禁是女性生活质量下降的重要原因。UI的意外出现及其在世界各地的高昂成本是显而易见的。UI的管理采用了多种方法；然而，世界范围内还没有就这些方法达成一致。传统医学是人类医学经验的来源，本研究回顾了最著名的波斯医学（PM）医生阿维森纳的著作，以了解他治疗UI的方法。选择关键词：“女性尿失禁”、“生活方式”、“营养”。作为一项图书馆研究，阿维森纳（公元980-1037年）的《医学经》（Al-Qanun-Fial-Tibb）被审查并编码。其他一些著名的PM书籍，如Rhazes（公元865-925年）的《大大陆》（Al Hawi fi Al Tibb）和Ibn Al-Nafis Al-Qarshi（公元1213-1288年）的“医学综合书籍”（Al Shamil fi Al-Sana'a Al Tibbiya），都被用来帮助解释这些代码，以备不时之需。现代文学在谷歌学者、PubMed和Magiran等电子数据库中使用相同的关键词进行搜索。最后，对结果进行了比较。最近的研究关注UI治疗中的保守和生活方式管理。在PM中，生活方式管理原则（Setteh-e-zarurieh）是预防和治疗的主要特征之一，有六个基本原则，包括天气、饮食、睡眠和清醒、运动和休息、疏散和保持以及心理和精神反应。在健康人身上，这六条轴线是由气质和个人特征设计的。在这份手稿中，我们讨论了五种提到的亚型。这些管理适合于设计各种临床试验，以调查其对女性UI的影响。
{"title":"Avicenna’s Points in Improving Female Urinary Incontinence with Lifestyle Options","authors":"Nematollah Masoudi, Z. Niktabe, M. Tabarrai, A. Masoudi, F. Ghorat, Fatemeh Moradi, A. Abbassian","doi":"10.18502/tim.v7i4.11496","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11496","url":null,"abstract":"Urinary Incontinence (UI) is a significant reason for the decline in women's quality of life. The unexpected occurrence of UI and its high costs around the world are evident. Numerous methods are used for the management of UI; however, there is no worldwide agreement on any of these methods. Traditional medicines are a source of human medical experiences and this study is a review on the books of the most famous Persian medicine (PM) physician, Avicenna, to find about his approach to UI. Keywords such as: \"female urinary incontinence\", \"lifestyle\", and “nutrition” were selected. As a library research, Avicenna’s (980- 1037 AD) \"the Canon of Medicine\" (Al-Qanun Fi al-Tibb), was reviewed and coded. Some other PM famous books like \"the Great Continens\" (Al-Hawi fi Al-Tibb) of Rhazes (865- 925 AD) and \"The Comprehensive Book on Medicine\" (Al-Shamil fi Al-Sana'a Al-Tibbiya) of Ibn al-Nafis al-Qarshi (1213- 1288 AD) were used as a help to interpret the codes just in case it was required. Modern literature was searched with the same keywords at electronic databases such as Google Scholar, PubMed, and Magiran. Finally, the results were compared. Recent studies care on conservative and lifestyle management in the treatment of UI. In PM, principles of lifestyle management (Setteh-e-zarurieh) is one of the main characteristics of prevention and treatment with six essential principles including weather, eating and drinking, sleep and wakefulness, movement and rest, evacuation and retention, and psychological and mental reactions. In healthy people, these six axes are designed by temperament and personal characteristics. In this manuscript, we discussed five mentioned subtypes. These managements are appropriate for designing various pieces of clinical trials to survey their effects on female UI.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48486104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artemisia essential oils have been used in flavors, scents, mice repellents, cleansers, beauty care products, fragrances, and conventional pharmaceuticals. This work analyzed the phytoconstituents, in vitro antibacterial activity, and toxicity of essential oils of three Artemisia species growing in Wolaita, Ethiopia. GC-MS has been used to analyze chemical composition. In vitro antibacterial activity was assessed by disc diffusion and broth dilution techniques. The MTT assay was used to conduct toxicity studies. The main components of the essential oil extracted from Artemisia afra Jacq. ex Willd. were camphor (19.2%), followed by 1,8-cineole (17.8%), artemisia ketone (15.2%), artemisyl acetate (6.9%), and camphene (6.6%). In the Artemisia annua L. oil, the main constituents were camphor (21.8%), artemisia alcohol (18.1%), santolina triene (11.6%), -copaene (9.1%), sabinene (4.5%), and δ-cadinene (4.0%). In addition, the main phytochemicals of Artemisia abyssinica Sch.Bip. ex A.Rich. oil were yomogi alcohol (39.3%), followed by cis β-farnesene (10.9%), β-selinene (6.7%), β-copaene (5.2%), and nerolidol (5.1%). The essential oils of A. afra, A. annua, and A. abyssinica showed significant antibacterial activity at low molar concentrations, with MIC values of 0.31, 0.15, and 0.62 μL against Staphylococcus aureus and 0.62, 0.31, and 1.25 μL against E. coli, respectively, compared with standard broad-spectrum gentamicin (0.25 μL). A. afra, A. annua, and A. abyssinica oils were showed weak toxicity to Vero cell lines with IC50 values of 178.47 µg/mL, 183.86 µg/mL, and 187.46 µg/mL, respectively. This result suggests that EOs are promising antibacterial agents given their weak toxic effects on normal cell lines at low concentrations.
{"title":"Essential Oils Composition, Antibacterial Activity and Toxicity Study of Artemisia Species Growing in Ethiopia","authors":"Mesfin Bibiso, M. Anza, T. Tadesse","doi":"10.18502/tim.v7i4.11495","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11495","url":null,"abstract":"Artemisia essential oils have been used in flavors, scents, mice repellents, cleansers, beauty care products, fragrances, and conventional pharmaceuticals. This work analyzed the phytoconstituents, in vitro antibacterial activity, and toxicity of essential oils of three Artemisia species growing in Wolaita, Ethiopia. GC-MS has been used to analyze chemical composition. In vitro antibacterial activity was assessed by disc diffusion and broth dilution techniques. The MTT assay was used to conduct toxicity studies. The main components of the essential oil extracted from Artemisia afra Jacq. ex Willd. were camphor (19.2%), followed by 1,8-cineole (17.8%), artemisia ketone (15.2%), artemisyl acetate (6.9%), and camphene (6.6%). In the Artemisia annua L. oil, the main constituents were camphor (21.8%), artemisia alcohol (18.1%), santolina triene (11.6%), -copaene (9.1%), sabinene (4.5%), and δ-cadinene (4.0%). In addition, the main phytochemicals of Artemisia abyssinica Sch.Bip. ex A.Rich. oil were yomogi alcohol (39.3%), followed by cis β-farnesene (10.9%), β-selinene (6.7%), β-copaene (5.2%), and nerolidol (5.1%). The essential oils of A. afra, A. annua, and A. abyssinica showed significant antibacterial activity at low molar concentrations, with MIC values of 0.31, 0.15, and 0.62 μL against Staphylococcus aureus and 0.62, 0.31, and 1.25 μL against E. coli, respectively, compared with standard broad-spectrum gentamicin (0.25 μL). A. afra, A. annua, and A. abyssinica oils were showed weak toxicity to Vero cell lines with IC50 values of 178.47 µg/mL, 183.86 µg/mL, and 187.46 µg/mL, respectively. This result suggests that EOs are promising antibacterial agents given their weak toxic effects on normal cell lines at low concentrations.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42457539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asim Ali Khan, Aanchal Anant Awasthi, S. Saeed, S. Parveen, J. Kishore, R. Janardhanan, W. Selvamurthy
Unani medicine is one of the traditional medical systems in India that is practiced and taught in an organized manner. While going through the literature, it has been observed that in the past, not many efforts have been made to understand the awareness level and utilization pattern among the population. This systematic review was conducted to better understand the awareness and utilization pattern of Unani medicine in India. Using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guideline, the results of survey-based studies conducted about the awareness and utilization pattern of Unani medicine in India were systematically reviewed. Thirteen studies conducted on awareness or utilization patterns, which exclusively represented data on Unani medicine and not Ayurveda, Yoga, Naturopathy, Unani, Siddha and Homeopathy (AYUSH) in general, were included in the present systematic review. A wide variation regarding awareness of Unani medicine is observed, ranging from 28.9% to 100% in different populations. Only five studies reported utilization patterns, which also varied considerably (13.8% to 74%). Unani Medicine is generally used in musculoskeletal disorders (20%-60.2%) and skin disorders (21.1%-64.9%). On the other hand, fifty-seven papers on surveys of CAM and AYUSH were found regarding utilization and consumption patterns. The findings demonstrate that thirteen papers entirely focused on the Unani System of Medicine. Henceforth, the awareness of the Unani system of Medicine has not been reported among the masses, and to provide its maximum benefits, certain strategies need to be formulated.
{"title":"Awareness and Utilization Pattern of Unani Medicine in India: A Systematic Review","authors":"Asim Ali Khan, Aanchal Anant Awasthi, S. Saeed, S. Parveen, J. Kishore, R. Janardhanan, W. Selvamurthy","doi":"10.18502/tim.v7i4.11497","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11497","url":null,"abstract":"Unani medicine is one of the traditional medical systems in India that is practiced and taught in an organized manner. While going through the literature, it has been observed that in the past, not many efforts have been made to understand the awareness level and utilization pattern among the population. This systematic review was conducted to better understand the awareness and utilization pattern of Unani medicine in India. Using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guideline, the results of survey-based studies conducted about the awareness and utilization pattern of Unani medicine in India were systematically reviewed. Thirteen studies conducted on awareness or utilization patterns, which exclusively represented data on Unani medicine and not Ayurveda, Yoga, Naturopathy, Unani, Siddha and Homeopathy (AYUSH) in general, were included in the present systematic review. A wide variation regarding awareness of Unani medicine is observed, ranging from 28.9% to 100% in different populations. Only five studies reported utilization patterns, which also varied considerably (13.8% to 74%). Unani Medicine is generally used in musculoskeletal disorders (20%-60.2%) and skin disorders (21.1%-64.9%). On the other hand, fifty-seven papers on surveys of CAM and AYUSH were found regarding utilization and consumption patterns. The findings demonstrate that thirteen papers entirely focused on the Unani System of Medicine. Henceforth, the awareness of the Unani system of Medicine has not been reported among the masses, and to provide its maximum benefits, certain strategies need to be formulated.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":"15 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41264013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farshad Alemi, M. Azimi, R. Moeini, H. Shirafkan, M. Bayani, M. Mojahedi, Haleh Tajadini
Diabetic peripheral neuropathy is one of the most common causes of disability in diabetic patients. Applying a method to achieve the highest therapeutic effect in patients is desirable. Therefore, this study aimed to evaluate the impact of leech therapy on diabetic neuropathy of lower limbs in comparison to gabapentin as a standard method. This randomized controlled parallel-group clinical trial was conducted among 40 patients with type II diabetes who were diagnosed with lower limb diabetic neuropathy and referred to specialized outpatient clinics in Babol, Mazandaran province, Iran from 23 September 2020 to 17 March 2021. The patients were randomly divided into two groups. One group was treated with leech therapy and the other group was treated with gabapentin as the standard method. The severity of neuropathy was assessed every 15 days until the 45th day. The Visual Analog Scale (VAS), Neuropathy Symptom Score (NSS), Neuropathy Disability Score (NDS), and Nerve Conduction Velocity (NCV), and Electromyography (EMG) were used for assessing the study outcomes. The repeated measure and Friedman tests were used by SPSS.V.23. The results of our study indicated that pain (P value:0.03), numbness (P value˂0.0001), and paranesthesia (P value:0.01) significantly reduced in patients undergoing leech therapy versus patients taking gabapentin on the 45th day. The total NSS (P value˂0.0001) and total NDS (P value˂0.0001) improved significantly for patients with leech therapy over 45 days compared to the patients with gabapentin. The results of our study showed that using leech therapy for patients with diabetic neuropathy was more effective in improving clinical symptoms and the functions of lower limb muscles and nerves in comparison to gabapentin. The severity and symptoms of neuropathy greatly improved for the patients treated with leech therapy versus patients taking gabapentin.
{"title":"The Effectiveness of Leech Therapy in the Severity of Diabetic Neuropathy: A Randomized Controlled Trial","authors":"Farshad Alemi, M. Azimi, R. Moeini, H. Shirafkan, M. Bayani, M. Mojahedi, Haleh Tajadini","doi":"10.18502/tim.v7i4.11488","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11488","url":null,"abstract":"Diabetic peripheral neuropathy is one of the most common causes of disability in diabetic patients. Applying a method to achieve the highest therapeutic effect in patients is desirable. Therefore, this study aimed to evaluate the impact of leech therapy on diabetic neuropathy of lower limbs in comparison to gabapentin as a standard method. This randomized controlled parallel-group clinical trial was conducted among 40 patients with type II diabetes who were diagnosed with lower limb diabetic neuropathy and referred to specialized outpatient clinics in Babol, Mazandaran province, Iran from 23 September 2020 to 17 March 2021. The patients were randomly divided into two groups. One group was treated with leech therapy and the other group was treated with gabapentin as the standard method. The severity of neuropathy was assessed every 15 days until the 45th day. The Visual Analog Scale (VAS), Neuropathy Symptom Score (NSS), Neuropathy Disability Score (NDS), and Nerve Conduction Velocity (NCV), and Electromyography (EMG) were used for assessing the study outcomes. The repeated measure and Friedman tests were used by SPSS.V.23. The results of our study indicated that pain (P value:0.03), numbness (P value˂0.0001), and paranesthesia (P value:0.01) significantly reduced in patients undergoing leech therapy versus patients taking gabapentin on the 45th day. The total NSS (P value˂0.0001) and total NDS (P value˂0.0001) improved significantly for patients with leech therapy over 45 days compared to the patients with gabapentin. The results of our study showed that using leech therapy for patients with diabetic neuropathy was more effective in improving clinical symptoms and the functions of lower limb muscles and nerves in comparison to gabapentin. The severity and symptoms of neuropathy greatly improved for the patients treated with leech therapy versus patients taking gabapentin.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48943600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostafa Dehghani Ashkezari, M. Parvizi, Yasaman Vazani
The use of complementary and alternative medicine is increasing throughout the world. Traditional Persian medicine, with a long history, is well known as a branch of complementary and alternative medicine and has a role in the prevention and treatment of diseases. Knowledge, attitude, and practice toward Persian medicine among Medical School staff were assessed in this study because of the importance of education in this field. This cross-sectional study was performed in 2020. As there was no specific questionnaire for assessment of knowledge, attitude, and practice toward Persian medicine, data were collected by a researcher-made questionnaire that was found to be both valid and reliable; the data were then analyzed statistically using SPSS software version 25. One hundred and fifty-three staff members were included in this study. The average score of performance in using treatment modalities in traditional Persian medicine was moderate, but the average score of knowledge about Persian medicine treatment modalities was low. The average score of attitude was positive, and 66.6% of people agreed with participating in the short-term course of traditional Persian medicine. The participants in this study showed moderate performance and a positive attitude towards traditional Persian medicine despite little knowledge of different Persian medicine treatment modalities. Most people expressed a desire to get acquainted with it. Therefore, it is suggested that courses be held to inform the staff about traditional Persian medicine.
{"title":"Assessment of Knowledge, Attitude, and Practice toward Persian Medicine among Medical School Staff","authors":"Mostafa Dehghani Ashkezari, M. Parvizi, Yasaman Vazani","doi":"10.18502/tim.v7i4.11493","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11493","url":null,"abstract":"The use of complementary and alternative medicine is increasing throughout the world. Traditional Persian medicine, with a long history, is well known as a branch of complementary and alternative medicine and has a role in the prevention and treatment of diseases. Knowledge, attitude, and practice toward Persian medicine among Medical School staff were assessed in this study because of the importance of education in this field. This cross-sectional study was performed in 2020. As there was no specific questionnaire for assessment of knowledge, attitude, and practice toward Persian medicine, data were collected by a researcher-made questionnaire that was found to be both valid and reliable; the data were then analyzed statistically using SPSS software version 25. One hundred and fifty-three staff members were included in this study. The average score of performance in using treatment modalities in traditional Persian medicine was moderate, but the average score of knowledge about Persian medicine treatment modalities was low. The average score of attitude was positive, and 66.6% of people agreed with participating in the short-term course of traditional Persian medicine. The participants in this study showed moderate performance and a positive attitude towards traditional Persian medicine despite little knowledge of different Persian medicine treatment modalities. Most people expressed a desire to get acquainted with it. Therefore, it is suggested that courses be held to inform the staff about traditional Persian medicine.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42645573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chronic diseases are the most common non-communicable diseases worldwide. Today, with the increase in the elderly population, the burden of the disease is gradually increasing, and alternative treatment methods for these diseases are gaining importance. Potential adverse reactions, contraindications, and interactions with prescription drugs and herbals are important to evaluate. Therefore, the use of plants by chronic patients should be under supervision of health professionals. In this study, we aimed to obtain comprehensive data by questioning the plants used by patients using drugs for chronic disease, their usage patterns, and changes seen as a result of plant use. For this purpose, 60 people over the age of 18 (47% female, 53% male) participated in the survey study, and 53.3% of the patients stated that they used plants in the treatment. Twenty-one plants have been identified. Linden and mint-lemon mixture are the most commonly used plants, accounting for 62% and 15% of the total, respectively. The most commonly used preparation method is decoction (60%). 62.5% of the users obtain the plants from herbalists' stores; 59.37% of the patients learned the use of plants through advice (friend, neighbor, relative); 96.87% of the patients stated that they benefited from the use of plants. According to these results, the patients need to be informed about the use of plants as a complementary treatment. Thus, further efforts should be made to raise awareness of the use of herbal medicine and possibility of herb-drug interactions among physicians and other health professionals.
{"title":"A Questionnaire-Based Study on Medicinal Plant Use in Patients with a Chronic Disease Diagnosis","authors":"B. Gürdal, Ebru Yesin","doi":"10.18502/tim.v7i4.11490","DOIUrl":"https://doi.org/10.18502/tim.v7i4.11490","url":null,"abstract":"Chronic diseases are the most common non-communicable diseases worldwide. Today, with the increase in the elderly population, the burden of the disease is gradually increasing, and alternative treatment methods for these diseases are gaining importance. Potential adverse reactions, contraindications, and interactions with prescription drugs and herbals are important to evaluate. Therefore, the use of plants by chronic patients should be under supervision of health professionals. In this study, we aimed to obtain comprehensive data by questioning the plants used by patients using drugs for chronic disease, their usage patterns, and changes seen as a result of plant use. For this purpose, 60 people over the age of 18 (47% female, 53% male) participated in the survey study, and 53.3% of the patients stated that they used plants in the treatment. Twenty-one plants have been identified. Linden and mint-lemon mixture are the most commonly used plants, accounting for 62% and 15% of the total, respectively. The most commonly used preparation method is decoction (60%). 62.5% of the users obtain the plants from herbalists' stores; 59.37% of the patients learned the use of plants through advice (friend, neighbor, relative); 96.87% of the patients stated that they benefited from the use of plants. According to these results, the patients need to be informed about the use of plants as a complementary treatment. Thus, further efforts should be made to raise awareness of the use of herbal medicine and possibility of herb-drug interactions among physicians and other health professionals.","PeriodicalId":52659,"journal":{"name":"Traditional and Integrative Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42927814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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