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Therapeutic Competencies in Reducing Emotional and Social Distress after Cognitive Behavior Therapy Training Program 认知行为治疗训练项目后减少情绪和社会困扰的治疗能力
Pub Date : 2019-08-03 DOI: 10.26697/ijsa.2020.1.7
Zizi Elsayed Ibrahim Sabra, Abdelmohsen Ibrahim Daigham
This study is interested in investigating how cognitive therapy training could help school psychologists to offer better help for students known with emotional and social problems. School psychologists are capable to help students with their psychological problems, as they spend relatively long time with them and know about their strengths and weaknesses as well. Adjustment in school environment is very important and has a great impact on student's overall adjustment and psychological health.
本研究旨在调查认知治疗培训如何帮助学校心理学家为已知有情绪和社会问题的学生提供更好的帮助。学校心理学家能够帮助学生解决他们的心理问题,因为他们与他们相处的时间相对较长,也了解他们的长处和短处。学校环境的调整非常重要,对学生的整体适应和心理健康有很大影响。
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引用次数: 1
Progression of Treating Alzheimer’s Disease with Stem Cell-based Therapies 干细胞疗法治疗阿尔茨海默病的进展
Pub Date : 2019-07-28 DOI: 10.21467/IAS.8.1.38-46
J. Ahmed, H. Rahman
Alzheimer’s disease is one form of dementia affecting a significant proportion of the population. The etiology of this prevalent disease is currently unknown. It is postulated that AD can be treated by using stem cell-based therapies by replacing the lost neurons in the atrophic regions of the brain. For these novel therapies to be successful several sources of stem cells have been proposed, such as pluripotent stem cells as well as multipotent stem cells. Proof of concept in animal studies have shown that stem cells can grafted into the affected regions or delivered intravenously into affected parts of the brain. These experiments had improved cognition and memory performance in rodents. The promising results seen in animal models have increased interest in conducting clinical trials using the same technique. In the last 5 years, several treatments have reached phase II clinical trials.  
阿尔茨海默病是影响很大一部分人口的痴呆症的一种形式。这种流行疾病的病因目前尚不清楚。据推测,阿尔茨海默病可以通过干细胞疗法来治疗,通过替换大脑萎缩区域失去的神经元。为了使这些新疗法取得成功,已经提出了几种干细胞来源,如多能干细胞和多能干细胞。动物研究的概念证明表明,干细胞可以移植到受影响的区域或静脉注射到受影响的大脑部位。这些实验改善了啮齿动物的认知和记忆表现。在动物模型中看到的有希望的结果增加了使用相同技术进行临床试验的兴趣。在过去的5年里,一些治疗方法已经进入了II期临床试验。
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引用次数: 0
Infant with Life Threatening Thymic Carcinoma 患有危及生命的胸腺癌的婴儿
Pub Date : 2019-07-26 DOI: 10.21467/IAS.7.1.53-57
B. K. Abdullah, Zardasht Bakr Mohammed, K. H. Salih, A. Baram, Dashti Latif Muhealddina, A. Qadir, R. Shrif, Rzgar Ghareeb Muhamed
Thymic epithelial neoplasms consist of thymomas, thymic carcinoids and thymic carcinomas. Carcinomas are malignant tumors of the thymus; they compromise only 4%-14% of thymic epithelial neoplasms. Thymic carcinoma cells do not resemble healthy cells but similar to cancer cells that originate from other parts of the body and grow more quickly when the tumor is found and more difficult to treat. Thymic carcinoma rarely occurs in children. We reported a case of undifferentiated thymic carcinoma in 11 months old female. After two courses of chemotherapy the patient developed increasing respiratory compression and unfortunately died because of respiratory failure.
胸腺上皮肿瘤包括胸腺瘤、胸腺类癌和胸腺癌。癌是胸腺的恶性肿瘤;它们仅损害4%-14%的胸腺上皮肿瘤。胸腺癌细胞与健康细胞不相似,但与源于身体其他部位的癌细胞相似,当肿瘤被发现时,癌细胞生长得更快,更难治疗。胸腺癌很少发生于儿童。我们报告一例11个月大的女性未分化胸腺癌。经过两个疗程的化疗后,患者出现呼吸压迫加重,不幸因呼吸衰竭而死亡。
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引用次数: 0
The Prevalence of Congenital Malaria 先天性疟疾的流行
Pub Date : 2019-07-22 DOI: 10.21467/IAS.8.1.22-29
E. Etefia
This study was aimed at highlighting on the prevalence of malaria among pregnant women in Nigeria within the last ten years. The prevalence of congenital malaria in Nigeria varies and it affects every geopolitical zone in Nigeria. This is because Nigeria like other countries in the tropics and subtropics has factors which favour the survival of mosquito. Although the World Health Organization (WHO) recommends the use of insecticide treated nets and effective case management of uncomplicated malaria as a feasible and cost-effective control strategy, Nigeria remains one of the worst affected countries in the world with malaria among pregnant women and neonates. This paper recommends more programs to the menace of this infection among pregnant women and neonates in Nigeria.
这项研究的目的是强调过去十年来尼日利亚孕妇中疟疾的流行情况。尼日利亚先天性疟疾的流行情况各不相同,影响到尼日利亚的每一个地缘政治区域。这是因为尼日利亚像其他热带和亚热带国家一样,具有有利于蚊子生存的因素。虽然世界卫生组织(世卫组织)建议使用经杀虫剂处理的蚊帐和对简单疟疾进行有效的病例管理,作为一项可行和具有成本效益的控制战略,但尼日利亚仍然是世界上孕妇和新生儿中受疟疾影响最严重的国家之一。本文建议更多的方案,以这种感染的威胁孕妇和新生儿在尼日利亚。
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引用次数: 0
Survey on Security for WSN based VANET using ECC 基于ECC的基于WSN的VANET安全性研究
Pub Date : 2019-07-22 DOI: 10.21467/IAS.8.1.30-37
Ravi Kalkundri, Rajashri Khanai, K. Praveen
With the increase in population, there is an increase in the number of car users drastically. Around the world, either millions of people die due to car accidents or they are severely injured by the accident. Most of the accidents occur due to lack of common information the drivers, as the lane change, applying sudden break, traffic congestion, etc, are the causes of accidents. Safety information such as speed limits, road conditions, traffic status, accidents, etc..., are used in some countries, but still more work is to be achieved. Vehicular Ad Hoc Networks (VANET) should be implemented and they should collect and distribute necessary safety information to other vehicles. VANET is a combination of Road Side Units (RSU’s) and On-Board Units (OBU’s). These RSU’s and OBU’s consist of various sensors, which are used to collect various data. The data collected by the sensors on the OBU’s on the vehicles can either be sent to another vehicle or can be displayed to the driver. Similarly, the sensor collects data at the RSU and sends the data to other RSU or depending on its nature and importance, the RSU may even be broadcasted to other vehicles. The main objective is to provide safety to the drivers, the passengers and to the information that is being transmitted between the nodes. However, in some scenarios, VANET’s may not guarantee timely detection of issues or any type of dangerous. We propose a solution by the integration of VANET and WSN to create a hybrid infrastructure with the in inexpensive wireless sensor nodes integrated on RSU’s along the roadside and on the OBU’s in the vehicle. As the new hybrid structure is proposed, there may be challenges that may occur. This article discussed these challenges and solutions to create an efficient and well-organized VANET-WSN Hybrid network.
随着人口的增长,汽车使用者的数量急剧增加。在世界各地,要么数百万人死于车祸,要么他们在事故中严重受伤。大多数事故是由于驾驶员缺乏共同信息而发生的,如变道、急刹车、交通拥堵等都是事故的原因。安全信息,如限速、路况、交通状况、事故等。,在一些国家使用,但仍有更多的工作要做。应实施车辆自组织网络(VANET),收集和分发必要的安全信息给其他车辆。VANET是路旁单元(RSU)和车载单元(OBU)的组合。这些RSU和OBU由各种传感器组成,用于收集各种数据。车辆OBU上的传感器收集的数据可以发送给另一辆车,也可以显示给驾驶员。同样,传感器在RSU收集数据并将数据发送给其他RSU,或者根据其性质和重要性,RSU甚至可以广播给其他车辆。其主要目标是为驾驶员、乘客以及在节点之间传输的信息提供安全保障。然而,在某些情况下,VANET可能无法保证及时发现问题或任何类型的危险。我们提出了一个解决方案,通过集成VANET和WSN来创建一个混合基础设施,将廉价的无线传感器节点集成在路边的RSU和车辆的OBU上。随着新的混合结构的提出,可能会出现一些挑战。本文讨论了这些挑战和解决方案,以创建一个高效和组织良好的VANET-WSN混合网络。
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引用次数: 2
Application of Genetic Algorithm in Common Optimization Problems 遗传算法在常见优化问题中的应用
Pub Date : 2019-07-21 DOI: 10.21467/IAS.8.1.17-21
N. Topuria, O. Kikvidze
Use of non-deterministic algorithms for solving multi-variable optimization problems is widely used nowadays. Genetic Algorithm belongs to a group of stochastic biomimicry algorithms, it allows us to achieve optimal or near-optimal results in large optimization problems in exceptionally short time (compared to standard optimization methods). Major advantage of Genetic Algorithm is the ability to fuse genes, to mutate and do selection based on fitness parameter. These methods protect us from being trapped in local optima (Most of deterministic algorithms are prone to getting stuck on local optima). In this paper we experimentally show the upper hand of Genetic Algorithms compared to other traditional optimization methods by solving complex optimization problem.
非确定性算法在求解多变量优化问题中得到了广泛的应用。遗传算法属于一组随机仿生学算法,它允许我们在极短的时间内(与标准优化方法相比)在大型优化问题中获得最优或接近最优的结果。遗传算法的主要优点是能够进行基因融合、突变和基于适应度参数的选择。这些方法可以防止我们陷入局部最优状态(大多数确定性算法都容易陷入局部最优状态)。本文通过解决复杂的优化问题,通过实验证明了遗传算法相对于传统优化方法的优势。
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引用次数: 0
Phytochemical Screening and Antioxidant Potential of Selected Nigerian Vegetables 尼日利亚蔬菜的植物化学筛选及其抗氧化潜力
Pub Date : 2019-07-21 DOI: 10.21467/IAS.8.1.12-16
Yusuf Hassan, M. I. Barde
Reducing power activities of ten vegetables commonly consumed in Katsina State, Nigeria have been assessed with the view of establishing their antioxidant capacities. Preliminary, the phytochemicals of the individual plants were screened, and it was found that various constituents were present. In particular, flavonoids and anthraquinones were found in Ficus glumosa which also appeared to demonstrate the best reducing power activity (4.898 at 25 mg/L).
为了确定其抗氧化能力,对尼日利亚卡齐纳州常食用的十种蔬菜的抗氧化活性进行了评估。初步筛选了单株植物的化学成分,发现其含有多种成分。其中黄酮类化合物和蒽醌类化合物在25 mg/L时还原活性最高,为4.898。
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引用次数: 4
Identification of Novel Key Biomarkers in Simpson-Golabi-Behmel Syndrome (SGBS) Simpson-Golabi-Behmel综合征(SGBS)新型关键生物标志物的鉴定
Pub Date : 2019-07-21 DOI: 10.21467/IAS.8.1.1-11
Mujahed I. Mustafa, A. H. Abdelmoneim, Nafisa M Elfadol, Naseem S Murshed, Zainab O. Mohammed, Mohamed A. Hassan
The Simpson-Golabi-Behmel Syndrome (SGBS) or overgrowth Syndrome is an uncommon genetic X-linked disorder highlighted by macrosomia, renal defects, cardiac weaknesses and skeletal abnormalities. The purpose of the work was to classify the functional nsSNPs of GPC3 to serve as genetic biomarkers for overgrowth syndrome. The raw data of GPC3 gene were retrieved from dbSNP database and used to examine the most damaging effect using eight functional analysis tools, while we used I-mutant and MUPro to examine the effect of SNPs on GPC3 protein structure; The 3D structure of GPC3 protein is not found in the PDB, so RaptorX was used to create a 3D structural prototype to visualize the amino acids alterations by UCSF Chimera; For biophysical validation we used project HOPE; Lastly we run conservational analysis by BioEdit and Consurf web server respectively. Our results revealed three novel missense mutations (rs1460413167, rs1295603457 and rs757475450) that are that are more likely to be responsible for disturbance in the function and structure of GPC3. This work provides new insight into the molecular basis of overgrowth Syndrome by evidence from bioinformatics analysis. Three novel missense mutations (rs757475450, rs1295603457 and rs1460413167) are more likely to be responsible for disturbance in the function and structure of GPC3; therefore, they may be assisting as genetic biomarkers for overgrowth syndrome. As well as these SNPs can be used for the larger population-based studies of overgrowth syndrome.
辛普森-戈拉比-贝梅尔综合征(SGBS)或过度生长综合征是一种罕见的遗传性x连锁疾病,突出表现为巨大儿、肾脏缺陷、心脏虚弱和骨骼异常。这项工作的目的是对GPC3的功能性nssnp进行分类,以作为过度生长综合征的遗传生物标志物。从dbSNP数据库中检索GPC3基因的原始数据,使用8种功能分析工具检测其最具破坏性的影响,使用I-mutant和MUPro检测snp对GPC3蛋白结构的影响;由于在PDB中没有发现GPC3蛋白的3D结构,因此使用RaptorX创建了3D结构原型,以可视化UCSF Chimera的氨基酸变化;为了进行生物物理验证,我们使用了HOPE项目;最后分别在BioEdit和Consurf web服务器上进行了分析。我们的研究结果揭示了三个新的错意突变(rs1460413167, rs1295603457和rs757475450),它们更有可能对GPC3的功能和结构紊乱负责。本工作通过生物信息学分析的证据为过度生长综合征的分子基础提供了新的见解。三种新的错意突变(rs757475450、rs1295603457和rs1460413167)更可能导致GPC3功能和结构的紊乱;因此,它们可能有助于作为过度生长综合征的遗传生物标志物。此外,这些snp可用于更大规模的基于人群的过度生长综合征研究。
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引用次数: 1
Extraction and Characterization of Underutilized Seed Oils Sampled in South-western Nigeria 在尼日利亚西南部取样的未充分利用的种子油的提取和表征
Pub Date : 2019-06-30 DOI: 10.21467/IAS.7.1.48-52
O. Adeniyi
Citrullus lanatus (watermelon) and Sesamum indicum (sesame) are edible plants that provide a lot of nutritional benefits to man; despite their wide consumption and benefits, their seed oils remain underutilized. Seed oils from these plants found in south-western Nigeria were analyzed for their physico-chemical properties. Oil was extracted from the seeds using Soxhlet apparatus and n-hexane as the solvent; physico-chemical properties were determined using standard analytical procedures. Watermelon seed oil had a golden brown colour while sesame seed oil had a carton brown colour; they had saponification values of 258.99 mgKOH/g and 261.34 mgKOH/g respectively. Acid value ranged from 2.13 – 2.51 mgKOH/g; iodine value of 39.7 - 42.3 gI2/100g and peroxide value of 1.39 – 2.43 meqKOH/g was determined in the seed oils. Oils from these seeds have numerous domestic and industrial potentials such as cooking, frying, production of soaps, and cosmetics to mention a few.
西瓜(Citrullus lanatus)和芝麻(Sesamum indicum)是可食用的植物,为人类提供了很多营养价值;尽管他们的广泛消费和好处,他们的种子油仍然没有得到充分利用。对尼日利亚西南部发现的这些植物的种子油进行了理化性质分析。以正己烷为溶剂,用索氏仪从种子中提取油脂;理化性质用标准分析方法测定。西瓜籽油呈金棕色,芝麻油呈纸盒棕色;皂化值分别为258.99 mgKOH/g和261.34 mgKOH/g。酸值为2.13 ~ 2.51 mgKOH/g;测定了种子油的碘值为39.7 ~ 42.3 gI2/100g,过氧化值为1.39 ~ 2.43 meqKOH/g。从这些种子中提取的油具有许多家庭和工业潜力,例如烹饪,油炸,生产肥皂和化妆品等等。
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引用次数: 1
Post Bioremediation Effect on Soil Fertility using Substrate from Livestock Byproduct 畜禽副产品基质生物修复后对土壤肥力的影响
Pub Date : 2019-05-24 DOI: 10.21467/IAS.7.1.33-37
J. U. Ekenwosu
The purpose of this study was to examine data obtained from soil physicochemical properties before and after initiation of bioremediation using liquid manure as a nutrient source. Bioremediation was initiated by stimulating autochthonous microorganisms present in soil rhizosphere while remediation was determined by soil physicochemical status after nutrient amendment. Rhizomes of turmeric were planted in soil treated with liquid manure and control in a randomized complete block design (RCBD) with three replications. Data generated from soil physicochemical parameters both in the laboratory and field were analyzed before and after treatment/cultivation. The study showed that treated soil increased total nitrogen, organic matter, organic carbon, exchangeable potassium, cation exchange capacity (CEC), calcium and exchangeable phosphorus. On the other hand, it decreased soil acidity, pH and exchangeable aluminium. There were no observable differences in magnesium concentration. Soil texture had more sand and a corresponding decline in silt and clay. Findings in this study revealed that soil that benefitted from treatment option is statistically significant at 0.05 p-level.
本研究的目的是研究利用液体粪便作为营养源进行生物修复前后土壤理化性质的数据。生物修复是通过刺激土壤根际的原生微生物来启动的,而修复则是由养分修正后的土壤理化状态决定的。采用随机完全区组设计(RCBD), 3个重复种植姜黄根茎。分析了处理/栽培前后实验室和田间土壤理化参数产生的数据。研究表明,处理后土壤全氮、有机质、有机碳、交换性钾、阳离子交换容量(CEC)、钙和交换性磷均有所增加。另一方面,它降低了土壤的酸度、pH值和交换性铝。镁浓度无明显差异。土壤质地砂质较多,粉砂和粘质相应减少。本研究结果表明,土壤受益于处理方案在0.05 p水平上具有统计学意义。
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引用次数: 1
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International Journal of Science Annals
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