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Chronic noncommunicable diseases and COVID-19: How they both interact 慢性非传染性疾病与新冠肺炎:二者如何相互作用
IF 0.4 Pub Date : 2021-11-01 DOI: 10.4103/2468-8827.330648
M. Farkouh, Arrti Bhasin, D. Ko, Aviral Roy, I. Khurana, A. Chockalingam
This white paper will summarize the key topics, outcomes, and recommendations from the Canada-India Healthcare Summit 2021 COVID-19 Pandemic Response and Initiatives sessions held on May 20–21, 2021. In particular, the authors have focused their attention on topics on the effect of COVID-19 on noncommunicable diseases, depression, research on substance abuse, and post COVID-19 pain management. The authors have developed a better understanding of these conditions' interplay with COVID-19 infection. The paper also deals with important topics around the effects of NCD on COVID-19 and vice versa, as well as key considerations around research and development, innovation, policy, and finally, summarizes the ways forward in which Canada and India could collaborate strategically. We also include key points raised during the summit.
本白皮书将总结2021年5月20日至21日举行的加拿大-印度医疗保健峰会2021新冠肺炎疫情应对和倡议会议的关键主题、成果和建议。特别是,作者将注意力集中在新冠肺炎对非传染性疾病的影响、抑郁症、药物滥用研究和新冠肺炎后疼痛管理等主题上。作者对这些条件与新冠肺炎感染的相互作用有了更好的理解。该论文还涉及非传染性疾病对新冠肺炎的影响,以及研究与开发、创新、政策等方面的主要考虑因素,最后总结了加拿大和印度可以进行战略合作的方式。我们还包括首脑会议期间提出的要点。
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引用次数: 1
India between the waves 波涛之间的印度
IF 0.4 Pub Date : 2021-11-01 DOI: 10.4103/2468-8827.330657
K. Reddy
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引用次数: 0
Automated atrial fibrillation prediction using a hybrid long short-term memory network with enhanced whale optimization algorithm on electrocardiogram datasets 自动房颤预测使用混合长短期记忆网络与增强鲸鱼优化算法对心电图数据集
IF 0.4 Pub Date : 2021-11-01 DOI: 10.4103/2468-8827.330654
Chocko Valliappa, Revathi Kalyanasundaram, Sathiyabhama Balasubramaniam, Sankar Sennan, Nirmalesh K. Sampath Kumar
Background: Cardiac arrhythmias are one of the leading causes of heart failure. In particular, atrial fibrillation (AFib) is a kind of arrhythmia that can lead to heart stroke and myocardial infarction. It is very important and crucial to predict AFib at an early stage to prevent heart disease. Electrocardiogram is one of the premium diagnostic tools which is used by most of the researchers for predicting irregular heartbeats. There are many works carried out in finding heart disease using machine learning classifiers. Aims and Objectives: Deep learning based hybrid Long Short Term Memory (LSTM) network is hybridized with Enhanced Whale Optimization (EWO) to minimize the network optimization and configuration issues faced in the existing models and proposed to increases the accuracy of predicting AFib. Materials and Methods: The proposed LSTM network is hybridized with a EWO technique for predicting AFib. This study uses a hybrid LSTM EWO network for classifying the various output labels of heart disease. EWO is used to predict the most relevant features from the raw dataset. Then, the LSTM model is used to predict the AFib of a patient from normal ECG data. Results: The DL based LSTM EWO achieves better results in all the performance metrics by analyzing the optimized features in feature space, training, and testing phase and successfully obtains better performance in an effective manner. LSTM improves the accuracy by reducing the number of units in the hidden layer which optimizes the network configuration. The proposed model achieves 96.12% accuracy which is 12.81% higher than RF, 15.01% higher than GB, 28.04% higher than CART, and 16.92% higher than SVM. Conclusion: The proposed model hybrid LSTM network integrated EWO for predicting the AFib. The EWO is applied for selecting the most appropriate features needed for the model to learn and produce improvised performance. The optimization and network configuration problems faced in the existing studies are avoided by choosing the suitable number of LSTM units and the size of the time window. This has been implemented through LSTM units and their window size. In addition, we made a statistical examination to prove the importance of proposed work against other models. It is observed that the experimental results attained with 96% of accuracy, better than conventional models.
背景:心律失常是心力衰竭的主要原因之一。特别是心房颤动(AFib)是一种心律失常,可导致心脏中风和心肌梗死。早期预测心房纤颤对于预防心脏病的发生是非常重要和关键的。心电图是一种优质的诊断工具,被大多数研究人员用于预测心律不齐。在使用机器学习分类器寻找心脏病方面进行了许多工作。目的和目标:基于深度学习的混合长短期记忆(LSTM)网络与增强型鲸鱼优化(EWO)相结合,以最大限度地减少现有模型中面临的网络优化和配置问题,并提出提高预测AFib的准确性。材料和方法:提出的LSTM网络与EWO技术相结合,用于预测AFib。本研究使用混合LSTM EWO网络对心脏病的各种输出标签进行分类。EWO用于从原始数据集中预测最相关的特征。然后,利用LSTM模型从正常心电图数据中预测患者心房纤颤。结果:基于DL的LSTM EWO通过分析特征空间、训练阶段和测试阶段的优化特征,在所有性能指标上都取得了更好的结果,并成功地以有效的方式获得了更好的性能。LSTM通过减少隐藏层单元的数量来提高准确率,从而优化网络配置。该模型的准确率为96.12%,比RF高12.81%,比GB高15.01%,比CART高28.04%,比SVM高16.92%。结论:提出的模型混合LSTM网络集成了EWO预测AFib。EWO用于选择模型学习和产生即兴表演所需的最合适的特征。通过选择合适的LSTM单元数量和时间窗大小,避免了现有研究中面临的优化和网络配置问题。这是通过LSTM单元及其窗口大小实现的。此外,我们进行了统计检验,以证明所提出的工作对其他模型的重要性。实验结果表明,该模型的准确率为96%,优于传统模型。
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引用次数: 0
Biomedical advances in the treatment of COVID-19: An Indo-Canadian perspective 新冠肺炎治疗的生物医学进展:从印度和加拿大的角度
IF 0.4 Pub Date : 2021-11-01 DOI: 10.4103/2468-8827.330647
Rohin K. Iyer, V. Venkataramanan, G. Pierce, Nikita Thakkar, V. Natarajan, A. Chockalingam
This white paper summarizes the key outcomes, topics, and recommendations from the Canada-India Healthcare Summit 2021 Conference, Biotechnology Session, held on May 20–21, 2021. In particular, the authors have focused their attention on topics ranging from research and development into the etiology and treatment of COVID-19 to novel approaches, such as ultraviolet-C disinfection and cell and gene therapy. The paper also deals with important topics around the effects of food distribution and nutrition on COVID-19 and vice versa, as well as key considerations around research and development, innovation, policy, grants, and incentives, and finally, summarizes the ways in which Canada and India, being close allies, have already begun to partner to fight the pandemic (as well as future strategies to continue this excellent progress). We also include key points raised during the summit and summarize them as part of this white paper.
本白皮书总结了2021年5月20日至21日举行的2021年加拿大-印度医疗保健峰会生物技术会议的主要成果、主题和建议。特别是,作者将注意力集中在从新冠肺炎病因和治疗的研究与开发到紫外线-C消毒、细胞和基因治疗等新方法等方面。该论文还涉及食品分配和营养对新冠肺炎的影响,以及围绕研发、创新、政策、赠款和激励措施的关键考虑因素等重要主题,最后总结了加拿大和印度作为亲密盟友,已经开始合作抗击疫情(以及未来继续取得这一卓越进展的战略)。我们还包括首脑会议期间提出的要点,并将其总结为本白皮书的一部分。
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引用次数: 0
History of public health-distorted Indian contribution although significant for addressing noncommunicable diseases 公共卫生史扭曲了印度的贡献,尽管对解决非传染性疾病有重要意义
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_84_21
J. Thakur, H. Kaur
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引用次数: 0
Exploration of barriers to self-care practices among diabetic patients attending chronic disease clinic in an urban slum 城市贫民区慢性病门诊糖尿病患者自我护理障碍的探讨
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_40_21
A. Shah, Sandeep Mishra, P. Ravichandran
Background: Glycemic control in diabetes can be achieved by adopting self-care practices. It also leads to reduction of complications and improvement in the quality of life. Identification of barriers to adopting these practices can help devise strategies to overcome them. This study was conducted to understand the self-care practices among diabetics and the barriers affecting those practices among diabetics in the urban slum area. Materials and Methods: This qualitative study using Focus Group Discussions (FGDs) was conducted in a chronic disease Outpatient clinic in Mumbai, in November 2020. Four FGDs with 32 participants were conducted. Thematic analysis of the transcripts was done. Results: Three major themes were identified – living with diabetes, practices to maintain glycemic control, and potential barriers. Barriers for self-care practices were - confusing advice provided by family and doctors, feeling rejected (stigmatized), lack of motivation for exercise, complications of diabetes, lack of family cooperation, lack of knowledge on foot care, physical constraints, nonavailability of medications, lack of social and financial support, suboptimal knowledge regarding diabetes, and misconceptions. Conclusions: Motivating diabetic patients for regular physical activity by starting from simple indoor exercises to outdoor exercises are necessary. Counseling the family members on the complications of diabetes due to inappropriate dietary practices should be advocated. Improvement in doctor-patient communication and providing information on the foot care practices is the need of the hour.
背景:糖尿病患者的血糖控制可以通过采取自我保健措施来实现。它还可以减少并发症,提高生活质量。确定采用这些做法的障碍有助于制定克服这些障碍的战略。本研究旨在了解城市贫民区糖尿病患者的自我保健行为及影响自我保健行为的因素。材料和方法:本定性研究采用焦点小组讨论(fgd),于2020年11月在孟买的一家慢性病门诊进行。共进行了4次fgd,共32名参与者。对笔录进行了专题分析。结果:确定了三个主要主题-糖尿病患者,维持血糖控制的做法和潜在的障碍。自我保健实践的障碍是:家庭和医生提供的建议令人困惑,感觉被拒绝(污名化),缺乏锻炼的动力,糖尿病并发症,缺乏家庭合作,缺乏足部护理知识,身体限制,无法获得药物,缺乏社会和经济支持,关于糖尿病的知识不够理想,以及误解。结论:从简单的室内运动到室外运动,激励糖尿病患者进行有规律的体育锻炼是必要的。应提倡对因不适当的饮食习惯而引起的糖尿病并发症的家庭成员进行咨询。改善医患沟通和提供足部护理实践的信息是需要的时间。
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引用次数: 0
Dietary approaches in management of noncommunicable diseases: A review 非传染性疾病管理中的饮食方法:综述
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_63_21
Janeline Lunghar, A. Banu
The prevalence of noncommunicable diseases (NCDs) has increased drastically over recent decades, with 41 million deaths each year, equivalent to 71% of all deaths globally. Unhealthy food choices and food habits, excessive calories, and inactivity are apparent factors to NCDs, namely obesity, diabetes mellitus, cancer, and cardiovascular disease. Healthy dietary intake and calorie restrictions have a promising effect on longevity. Eventually, adopting these strategies may delay the onset and decrease the burden of NCDs. Recent findings proved that nutrition has a strong association with the prevalence of NCDs. American Institute for Cancer Research and the World Cancer Research Fund says 30%–40% of cancers are preventable by adopting healthy food choices, dietary restrictions, engaging in physical activity, and maintaining body mass index. This review focuses on dietary intake and dietary restrictions and finally leads to understand the vital role of gut microbiome in managing NCDs.
近几十年来,非传染性疾病的流行率急剧上升,每年有4100万人死亡,相当于全球所有死亡人数的71%。不健康的食物选择和饮食习惯、过量的卡路里和缺乏运动是非传染性疾病的明显因素,即肥胖、糖尿病、癌症和心血管疾病。健康的饮食摄入和热量限制对长寿有很好的影响。最终,采用这些策略可以延缓非传染性疾病的发病并减轻其负担。最近的研究结果证明,营养与非传染性疾病的患病率有着密切的联系。美国癌症研究所和世界癌症研究基金会表示,30%至40%的癌症可以通过选择健康的食物、限制饮食、进行体育活动和保持体重指数来预防。这篇综述的重点是饮食摄入和饮食限制,并最终了解肠道微生物组在管理非传染性疾病中的重要作用。
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引用次数: 1
Underweight and overweight/obesity among middle aged and older adults in India: Prevalence and correlates from a national survey in 2017–2018 印度中老年人体重不足和超重/肥胖:2017-2018年全国调查的患病率及其相关因素
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_9_21
S. Pengpid, K. Peltzer
Background and Objective : This study aimed to estimate the prevalence and correlates of underweight and overweight/obesity among middle aged and older adults in India. Materials and Methods : The cross-sectional sample consisted of 72,262 individuals (≥45 years) from the Longitudinal Aging Study in India Wave 1 in 2017–2018. Multinomial logistic regression was used to estimate the factors associated with underweight and overweight/obesity relative to normal weight. Results : The prevalence of normal weight (18.5–22.9 kg/m2) was 36.7%, underweight (<18.5 kg/m2) 20.8%, overweight (23.0–24.9 kg/m2) 14.2%, Class I obesity (25.0–29.9 kg/m2) 20.8%, and Class II obesity (≥30.0 kg/m2) 7.4%. In adjusted multinomial logistic regression, the factors positively associated with underweight were older age (≥70 years) (adjusted relative risk ratio [ARRR]: 1.94, confidence interval [CI]: 1.75–2.14), food insecurity (ARRR: 1.19, CI: 1.07–1.33), poor or fair self-rated health status (ARRR: 1.14, CI: 1.05–1.33), and current tobacco use (ARRR: 1.42, CI: 1.31–1.53). The factors negatively associated with underweight were higher education (≥10 years) (ARRR: 0.67, CI: 0.48–0.92), high subjective socioeconomic status (ARRR: 0.78, CI: 0.67–0.92), urban residence (ARRR: 0.72, CI: 0.61–0.84), high life satisfaction (ARRR: 0.83, CI: 0.75–0.91), hypertension (ARRR: 0.64, CI: 0.58–0.69), diabetes (ARRR: 0.50, CI: 0.42–0.59), and heart disease or stroke (ARRR: 0.74, CI: 0.61–0.89). The factors positively associated with overweight/obesity were higher education (≥10 years) (ARRR: 2.09, CI: 1.87–2.33), high subjective socioeconomic status (ARRR: 1.44, CI: 1.31–1.59), urban residence (ARRR: 1.94, CI: 1.79–2.11), high life satisfaction (ARRR: 1.12, CI: 1.04–1.20), hypertension (ARRR: 1.89, CI: 1.76–2.02), type 2 diabetes (ARRR: 1.80, CI: 1.59–2.04), and raised cholesterol (ARRR: 2.75, CI: 2.11–3.58). The factors negatively associated with overweight/obesity were older age (≥70 years) (ARRR: 0.44, CI: 0.39–0.49), male sex (ARRR: 0.59, CI: 0.54–0.64), food insecurity (ARRR: 0.85, CI: 0.76–0.94), vigorous physical activity (>once/week) (ARRR: 0.91, CI: 0.84–0.99), current tobacco use (ARRR: 0.69, CI: 0.64–0.74), and heavy episodic alcohol use (ARRR: 0.70, CI: 0.58–0.85). Conclusion : One in five middle-aged and older adults in India were underweight and more than two in five were overweight/obese, confirming a dual burden of malnutrition in India.
背景和目的:本研究旨在估计印度中老年人体重不足和超重/肥胖的患病率及其相关因素。材料和方法:横断面样本包括2017-2018年印度纵向老龄化研究中的72,262名个体(≥45岁)。使用多项逻辑回归来估计与体重不足和超重/肥胖相关的因素。结果:体重正常(18.5-22.9 kg/m2)的患病率为36.7%,体重不足(1次/周)(ARRR: 0.91, CI: 0.84-0.99),目前吸烟(ARRR: 0.69, CI: 0.64-0.74),以及严重的间歇性饮酒(ARRR: 0.70, CI: 0.58-0.85)。结论:印度五分之一的中老年人体重不足,超过五分之二的人超重/肥胖,证实了印度营养不良的双重负担。
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引用次数: 1
Factors associated with noncompliance to hypertension treatment in adults in a district health facility in north Dayi in the Volta Region of Ghana 加纳沃尔特地区达伊北部地区卫生机构成人不遵守高血压治疗的相关因素
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_51_21
Stephen Manortey, Sedinam Adamaley
Context: Hypertension is known to affect more than one billion of the world's population with complications such as stroke and myocardial infarction. Compliance with hypertension therapy is the extent to which one's behavior in following a diet plan, taking medications, or making lifestyle changes corresponds to the agreed recommendations from a health-care provider. This research explores factors influencing noncompliance to hypertension treatment in the North Dayi District of the Volta Region, Ghana. Aims: To determine the prevalence of noncompliance to hypertension therapy in patients diagnosed with hypertension in the study population. 1. To evaluate the knowledge of patients on hypertension. 2. To ascertain contributing factors influencing noncompliance to the treatment of hypertension. Settings and Design: A cross-sectional study. Methodology: A cross-sectional study was conducted from January 2021 to February 2021 in the North Dayi District. A sample of 191 respondents diagnosed with hypertension for at least 1 month with or without comorbidities and on treatment were selected using the systematic sampling method. An Adherence Barrier Questionnaire was adopted to assess reliability in the responses. Bivariate and multivariate analyses were done using noncompliance to hypertension therapy as the outcome of interest. Statistical Analysis Used: Fisher's Exact, logistic regression, Cronbach's alpha analysis. Results: Data were collected from 191 study participants between the ages of 25 and 101 years with an average age estimated at (62.2 ± 13.5) years. The prevalence of nonadherence to hypertension treatment in this study was 31.4% in the North Dayi District Hospital. The reported Marital status and Default review were statistically significant predictors of adherence to hypertension treatment at a chosen 95% Confidence Level. Conclusion: The degree of non-compliance to hypertension treatment was less than fifty per cent among respondents. The data suggests that strategies should be developed to help reduce waiting times for consultation at the Hypertension Clinic by the District Hospital in collaboration with other stakeholders.
背景:众所周知,高血压影响着世界上超过10亿的人口,并伴有中风和心肌梗死等并发症。高血压治疗的依从性是指一个人在遵循饮食计划、服用药物或改变生活方式方面的行为与卫生保健提供者商定的建议相一致的程度。本研究探讨了加纳Volta地区北达伊区高血压治疗不依从性的影响因素。目的:确定研究人群中被诊断为高血压的患者不遵守高血压治疗的发生率。1. 目的:评价患者对高血压的认知程度。2. 目的:探讨影响高血压治疗不遵医嘱的因素。环境与设计:一项横断面研究。方法:于2021年1月至2021年2月在北大邑区进行横断面研究。采用系统抽样方法,选取了191名被诊断为高血压且治疗至少1个月且伴有或不伴有合并症且正在接受治疗的受访者。采用依从性障碍问卷来评估回答的可靠性。双变量和多变量分析使用不遵守高血压治疗作为感兴趣的结果。统计分析:Fisher’s Exact, logistic回归,Cronbach’s alpha分析。结果:数据来自191名年龄在25至101岁之间的研究参与者,平均年龄估计为(62.2±13.5)岁。本研究中大邑县北区医院高血压治疗不依从率为31.4%。在95%的置信水平上,报告的婚姻状况和Default评价是高血压治疗依从性的统计学显著预测因子。结论:受访患者对高血压治疗的不依从程度低于50%。数据表明,应制定战略,帮助减少地区医院与其他利益相关者合作在高血压诊所就诊的等待时间。
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引用次数: 0
Clinical inertia in lipid screening and prescribing statins for primary prevention: Experience from a low-to-middle income country 脂质筛查和他汀类药物一级预防的临床惰性:来自中低收入国家的经验
IF 0.4 Pub Date : 2021-10-01 DOI: 10.4103/jncd.jncd_38_21
A. Matthias, Mathotage Nihari Padmasiri, Batheegama Kavindi Somathilake, Nethrani Wijesekara Pathirana
Introduction: Most adults who should be screened for dyslipidemia do not undergo lipid testing in low- to middle-income countries due to lack of resources and clinical inertia. Those eligible for statin therapy for cardiovascular disease (CVD) prevention are under treated possibly due to clinical inertia. This study aimed to find out the present lipid screening practices and prescribing of statins for primary prevention in a low- to middle-income country. Methods: This study was conducted at medical wards of Colombo South Teaching Hospital in patients with a first-time acute coronary syndrome (ACS), who have not been on treatment with statins and not diagnosed with dyslipidemia prior to this admission. Eligibility for lipid screening was assessed using U.S. preventive services task force recommendations. CVD risk prior to ACS was assessed by QRISK2 score. Lipid profile was done within 24 h. Results: Out of 125 participants, 70.4% had a QRISK2 >10 and were eligible for statins prior to their first episode of ACS. Eighty-four percent have not had a lipid screening and 91.4% were not aware of the need for it. 54.4% were not aware that the elevation of certain types of cholesterol leads to ACS. Of 125 patients (100 males/25 females), mean age 55.78 (26–82). Body mass index >23kg/m2 in 65.6%. 65.6% had some lipid abnormality. Total cholesterol >200 in 29.6%, low-density lipoprotein cholesterol >130 in 28.8%, triglyceride >150 in 31.2%, high-density lipoprotein cholesterol suboptimal in 67.2%. Discussion: Lipid screening is suboptimal. Most patients who were eligible for statins based on their CVD risk prior to their first episode of ACS, were not receiving statins prior to their first ACS. Patients should have their CVD risk estimated and statins should be given to eligible patients for prevention of ACS.
在中低收入国家,由于缺乏资源和临床惰性,大多数应该进行血脂异常筛查的成年人没有进行脂质检测。那些有资格接受他汀类药物治疗预防心血管疾病(CVD)的患者可能由于临床惯性而接受治疗不足。本研究旨在了解中低收入国家目前的脂质筛查做法和他汀类药物的一级预防处方。方法:本研究在科伦坡南教学医院病房对首次急性冠脉综合征(ACS)患者进行,这些患者入院前未接受他汀类药物治疗,也未诊断为血脂异常。脂质筛查的资格是根据美国预防服务工作组的建议进行评估的。通过QRISK2评分评估ACS前CVD风险。脂质分析在24小时内完成。结果:在125名参与者中,70.4%的受试者QRISK2为bb10,并且在首次ACS发作之前符合他汀类药物的使用条件。84%的人没有做过脂质筛查,91.4%的人没有意识到需要做脂质筛查。54.4%的人不知道某些类型胆固醇的升高会导致ACS。125例患者(男100例,女25例),平均年龄55.78岁(26-82岁)。体质指数>为23kg/m2者占65.6%。65.6%有脂质异常。总胆固醇>00占29.6%,低密度脂蛋白胆固醇>30占28.8%,甘油三酯>50占31.2%,高密度脂蛋白胆固醇次优占67.2%。讨论:脂质筛查是次优的。大多数在首次ACS发作前根据心血管疾病风险符合他汀类药物治疗条件的患者,在首次ACS发作前没有接受他汀类药物治疗。应该对患者的心血管疾病风险进行评估,并对符合条件的患者给予他汀类药物以预防ACS。
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引用次数: 0
期刊
International Journal of Noncommunicable Diseases
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