Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17409
L. Budiarti, Siti Kaidah, Nazla Puteri Azhari, Putri Putri
Eichhornia crassipes and Pistia stratiotes are weeds that often pollute water areas. These two contain various active compounds that act as antimicrobials, which have the potential as disinfection agents to prevent the transmission of pathogenic bacteria and fungi. An antimicrobial substance is said to be effective as a good disinfectant if it has a phenol coefficient value equal to or more than the 5% phenol comparison substance. The aim of this research was to test the effectiveness of a combination of Eichhornia crassipes and Pistia stratiotes extracts as a disinfection candidate through the phenol coefficient test. This in vitro experimental study was carried out using a dilution technique. The combination treatment of Eichhornia crassipes and Pistia stratiotes extracts and 5% phenol was tested against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and also Candida albicans yeast. Observations on the test media suspension tubes that were clear or did not show the growth of the test microbes for a period of 5, 10, and 15 minutes. The phenol coefficient value of the combination treatment of Eichhornia crassipes and Pistia stratiotes extracts was ≥1 with 5% phenol as comparison. Higher coefficient values were obtained for Staphylococcus aureus, equivalent values of 5% phenol were found for E.coli, P.aeruginosa, and C.albicans; whereas in S.typhi the value is <1. The combination treatment of E.crassipes and P.stratiotes extracts resulted in a phenol coefficient value equivalent to that of 5% phenol comparator, for several tested bacteria and yeasts. So it has effectiveness as a preparation for disinfection. The combination of Eichhornia crassipes and Pistia stratiotes extracts has antimicrobial effectiveness and can be developed as an alternative disinfection candidate.
{"title":"Coefficient Test of Antimicrobial Phenol Combination of Eichhornia crassipes and Pistia stratiotes Extract In Vitro as Alternative Disinfection Candidates","authors":"L. Budiarti, Siti Kaidah, Nazla Puteri Azhari, Putri Putri","doi":"10.20527/jbk.v19i2.17409","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17409","url":null,"abstract":"Eichhornia crassipes and Pistia stratiotes are weeds that often pollute water areas. These two contain various active compounds that act as antimicrobials, which have the potential as disinfection agents to prevent the transmission of pathogenic bacteria and fungi. An antimicrobial substance is said to be effective as a good disinfectant if it has a phenol coefficient value equal to or more than the 5% phenol comparison substance. The aim of this research was to test the effectiveness of a combination of Eichhornia crassipes and Pistia stratiotes extracts as a disinfection candidate through the phenol coefficient test. This in vitro experimental study was carried out using a dilution technique. The combination treatment of Eichhornia crassipes and Pistia stratiotes extracts and 5% phenol was tested against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and also Candida albicans yeast. Observations on the test media suspension tubes that were clear or did not show the growth of the test microbes for a period of 5, 10, and 15 minutes. The phenol coefficient value of the combination treatment of Eichhornia crassipes and Pistia stratiotes extracts was ≥1 with 5% phenol as comparison. Higher coefficient values were obtained for Staphylococcus aureus, equivalent values of 5% phenol were found for E.coli, P.aeruginosa, and C.albicans; whereas in S.typhi the value is <1. The combination treatment of E.crassipes and P.stratiotes extracts resulted in a phenol coefficient value equivalent to that of 5% phenol comparator, for several tested bacteria and yeasts. So it has effectiveness as a preparation for disinfection. The combination of Eichhornia crassipes and Pistia stratiotes extracts has antimicrobial effectiveness and can be developed as an alternative disinfection candidate.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17387
Nanang Miftah Fajari, Hendra Nur'amin
Diabetes mellitus (DM) is a high-burden disease in Indonesia especially in South Kalimantan Province. South Kalimantan province lies in mostly wetlands areas. Identification of risk factors related to DM is necessary to prevent the disease. We conducted this study to assess the prevalence of DM in the South Kalimantan people, the impact of a wetlands area on DM prevalence, and other significant risk factors. A cross-sectional study approach was used to identify significant risk factors. We used adjusted multiple logistic regression to assess the association between risk factors and DM prevalence. There were 4612 subjects more than 18 years old in this study with 6.5% of them diagnosed as DM. Most of the subjects live in wetlands area (79.1%) and most of them >40 years old. Several important risk factors associated with DM were identified. Subjects in wetlands have a lower risk of DM compared to non-wetlands area (OR 0.73, CI 95%; 0.43-0.71, p<0.001). Age >40 years old increase the risk of DM (OR 2.24, CI 95 % 1.61-3.10, p<0.001), hypertension (OR 1.65, CI 95% 1.23-2.21, p<0,001), waist circumference >90 cm (OR 2.12, CI 95%. p<0.001), cholesterol level (>200 mg/dl) with DM prevalence (OR 1.38, CI 95% 1.02-1.87, p<0.04) and family history of DM (OR 10.28, CI 95% 7.67-13.76, p<0.001). This study found that wetlands areas may reduce the DM prevalence and other risk factors may increase the prevalence of DM. Further research is necessary to establish the relationship between wetlands area and DM.
{"title":"The Effect of Wetland Geography on the Prevalence of Diabetes Mellitus in South Kalimantan","authors":"Nanang Miftah Fajari, Hendra Nur'amin","doi":"10.20527/jbk.v19i2.17387","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17387","url":null,"abstract":"Diabetes mellitus (DM) is a high-burden disease in Indonesia especially in South Kalimantan Province. South Kalimantan province lies in mostly wetlands areas. Identification of risk factors related to DM is necessary to prevent the disease. We conducted this study to assess the prevalence of DM in the South Kalimantan people, the impact of a wetlands area on DM prevalence, and other significant risk factors. A cross-sectional study approach was used to identify significant risk factors. We used adjusted multiple logistic regression to assess the association between risk factors and DM prevalence. There were 4612 subjects more than 18 years old in this study with 6.5% of them diagnosed as DM. Most of the subjects live in wetlands area (79.1%) and most of them >40 years old. Several important risk factors associated with DM were identified. Subjects in wetlands have a lower risk of DM compared to non-wetlands area (OR 0.73, CI 95%; 0.43-0.71, p<0.001). Age >40 years old increase the risk of DM (OR 2.24, CI 95 % 1.61-3.10, p<0.001), hypertension (OR 1.65, CI 95% 1.23-2.21, p<0,001), waist circumference >90 cm (OR 2.12, CI 95%. p<0.001), cholesterol level (>200 mg/dl) with DM prevalence (OR 1.38, CI 95% 1.02-1.87, p<0.04) and family history of DM (OR 10.28, CI 95% 7.67-13.76, p<0.001). This study found that wetlands areas may reduce the DM prevalence and other risk factors may increase the prevalence of DM. Further research is necessary to establish the relationship between wetlands area and DM.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17401
Framita Rahman, Brigita Sri Jane, M. C. P. Ngandoh, W. Saputri, Puspa Akhlakul Karima Tuhelelu
Adolescence is a crucial period of time and very challenging period. There is an increase concern on how social media use and mental health of teenagers. In Makassar City, there is a high number of mental health in adolescence yet still rare research has been conducted to investigates about social media use and self-esteem on teenagers. The aim of this study is to give a description on how adolescence behaviour on social media use and their level of self-esteem. This research uses a quantitative study with descriptive study design. The participant was selected based on some inclusion criteria such as teenagers’ age 16-18 years old, able to speak Bahasa, stay in Makassar City and willingly to become participant. The participant was determined by using non-probability sampling using convenience sampling method. There are 118 participants on this research. Three types of instruments were used; demography questionnaire, intensity of social media use and Rosenberg Self-Esteem Scale. From 118 participants, 19 were male and 99 were female. There are 42 respondents spend more than 6 hours on social media, and 54 respondents spend 2-6 hours on social media per day. Most of the respondents use their social media for see feed (20%), give like (14%), stalking (9%), news sharing (9%) and give comment (6%). Most of the respondents have high social media use (70 respondents) and low self-esteem (66 respondents). Social media use is quite high among teenagers in Makassar City and the self-esteem is mostly low. Thus, it is important to investigate the relationship of social media use and self-esteem so that it can give a comprehensive understanding on adolescence’s mental health and wellbeing in Makassar City
{"title":"Description of Social Media Use and Self-Esteem of Adolescents in Makassar City","authors":"Framita Rahman, Brigita Sri Jane, M. C. P. Ngandoh, W. Saputri, Puspa Akhlakul Karima Tuhelelu","doi":"10.20527/jbk.v19i2.17401","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17401","url":null,"abstract":"Adolescence is a crucial period of time and very challenging period. There is an increase concern on how social media use and mental health of teenagers. In Makassar City, there is a high number of mental health in adolescence yet still rare research has been conducted to investigates about social media use and self-esteem on teenagers. The aim of this study is to give a description on how adolescence behaviour on social media use and their level of self-esteem. This research uses a quantitative study with descriptive study design. The participant was selected based on some inclusion criteria such as teenagers’ age 16-18 years old, able to speak Bahasa, stay in Makassar City and willingly to become participant. The participant was determined by using non-probability sampling using convenience sampling method. There are 118 participants on this research. Three types of instruments were used; demography questionnaire, intensity of social media use and Rosenberg Self-Esteem Scale. From 118 participants, 19 were male and 99 were female. There are 42 respondents spend more than 6 hours on social media, and 54 respondents spend 2-6 hours on social media per day. Most of the respondents use their social media for see feed (20%), give like (14%), stalking (9%), news sharing (9%) and give comment (6%). Most of the respondents have high social media use (70 respondents) and low self-esteem (66 respondents). Social media use is quite high among teenagers in Makassar City and the self-esteem is mostly low. Thus, it is important to investigate the relationship of social media use and self-esteem so that it can give a comprehensive understanding on adolescence’s mental health and wellbeing in Makassar City","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17415
Sarmila Sarmila, Nafisah Nafisah, Hanna Habibah, Indah Saputri, Indah Setiawati, N. Komari
Pesticide active ingredients have widespread toxicity effects on target and non-target organisms. Continuous exposure to pesticides causes cancer. Kelakai is thought to have potential cytotoxic activity against the growth of cancer cells. The aim of this research is to examine the potential activity of chemical compounds on Anaplastic Lymphoma Kinase (ALK) proteins exposed to organophosphate pesticides in silico. Protein and ligand preparation with the Chimera program, Docking using SwissDock, as well as virtual screening using the pkCSM web and ProTox. Ethion and neophytadiene have the most negative ∆G values of -8.62 kcal/mol and -8.39 kcal/mol, respectively. The binding site for ethion and neophytadiene compounds with the ALK protein is right at the active site of the ALK protein. Ethion is the most toxic organophosphate pesticide and has the potential to be cytogenic. Neophytadiene from kelakai compounds has the potential to act as a competitor in inhibiting the ALK protein. The similarity in the type and number of binding residues in ethion and neophytadiene in the ALK protein indicates competition between ethion and neophytadiene.
{"title":"Potential of Chemical Compounds from Coloring Plants (Stenochlaena palutris) as Competitors for ALK Protein Damage Due To Pesticide Exposure: In Silico Study","authors":"Sarmila Sarmila, Nafisah Nafisah, Hanna Habibah, Indah Saputri, Indah Setiawati, N. Komari","doi":"10.20527/jbk.v19i2.17415","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17415","url":null,"abstract":"Pesticide active ingredients have widespread toxicity effects on target and non-target organisms. Continuous exposure to pesticides causes cancer. Kelakai is thought to have potential cytotoxic activity against the growth of cancer cells. The aim of this research is to examine the potential activity of chemical compounds on Anaplastic Lymphoma Kinase (ALK) proteins exposed to organophosphate pesticides in silico. Protein and ligand preparation with the Chimera program, Docking using SwissDock, as well as virtual screening using the pkCSM web and ProTox. Ethion and neophytadiene have the most negative ∆G values of -8.62 kcal/mol and -8.39 kcal/mol, respectively. The binding site for ethion and neophytadiene compounds with the ALK protein is right at the active site of the ALK protein. Ethion is the most toxic organophosphate pesticide and has the potential to be cytogenic. Neophytadiene from kelakai compounds has the potential to act as a competitor in inhibiting the ALK protein. The similarity in the type and number of binding residues in ethion and neophytadiene in the ALK protein indicates competition between ethion and neophytadiene.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17385
Pudji Andayani, Monica Anggriana Salim, P. G. Halim, A. Yunanto
Indonesia is ranked 7th in the country with the highest neonatal mortality rate in the world, respectively 60.000 neonatal deaths per year. Neonatal sepsis in one of the major causes of neonatal death. The aim of this study is to find the association of gestational age and birth weight with the incidence of neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021. This study is a retrospective study with a cross sectional approach at Neonatal Ward, Ulin Hospital Banjarmasin, South Borneo, January to December 2021. The total sample was 200 infants consisting of 100 healthy infants and 100 sepsis infants. The source of gestational age, birth weight, and diagnosis data were taken through patient medical records. The mean gestational age of healthy infant group was 38,45 weeks (all infants were at term) while in septic infant group was 33,59 weeks (70%preterm, 28%at-term, and 2%post-term). The average birth weight of healthy infant group was 3021.24 grams (all infants were normal birth weight) while in septic infant group was 2003,59 grams (25%normal birth weight, 40%low birth weight, 25%very low birth weight, and 10%extremely low birth weight). There were an association of gestational age and birth weight with neonatal sepsis, confidential rate was 95%. (p<0,000 and p<0,000). There were an association of gestational age and birth weight with neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021.
{"title":"Association Of Gestational Age And Birth Weight With Neonatal Sepsis In Ulin Hospital Banjarmasin","authors":"Pudji Andayani, Monica Anggriana Salim, P. G. Halim, A. Yunanto","doi":"10.20527/jbk.v19i2.17385","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17385","url":null,"abstract":"Indonesia is ranked 7th in the country with the highest neonatal mortality rate in the world, respectively 60.000 neonatal deaths per year. Neonatal sepsis in one of the major causes of neonatal death. The aim of this study is to find the association of gestational age and birth weight with the incidence of neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021. This study is a retrospective study with a cross sectional approach at Neonatal Ward, Ulin Hospital Banjarmasin, South Borneo, January to December 2021. The total sample was 200 infants consisting of 100 healthy infants and 100 sepsis infants. The source of gestational age, birth weight, and diagnosis data were taken through patient medical records. The mean gestational age of healthy infant group was 38,45 weeks (all infants were at term) while in septic infant group was 33,59 weeks (70%preterm, 28%at-term, and 2%post-term). The average birth weight of healthy infant group was 3021.24 grams (all infants were normal birth weight) while in septic infant group was 2003,59 grams (25%normal birth weight, 40%low birth weight, 25%very low birth weight, and 10%extremely low birth weight). There were an association of gestational age and birth weight with neonatal sepsis, confidential rate was 95%. (p<0,000 and p<0,000). There were an association of gestational age and birth weight with neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17421
Farida Heriyani, Ainun Farida, Maria Ulfah
Stunting is a condition of growth failure in children under five years old (toddlers) due to chronic malnutrition and recurrent infections, especially in the first 1,000 days of life. One of the indirect causes is the availability of clean water and poor sanitation. Lampihong Community Health Center Balangan Regency is one of the areas with the highest stunting cases in South Kalimantan. This study aims to analyze the relationship between home sanitation and clean water facilities with the incidence of stunting in the Lampihong Community Health Center, Balangan Regency. The research method is analytic observational with a case control approach. The research sample consisted of 30 mothers of stunted toddlers as the case group and 30 mothers of non-stunted toddlers as the control group. Data analysis used the chi square test at a 95% confidence level. The research results showed that the majority of stunted toddlers lived in houses with unhealthy water closet, wastewater disposal and waste management that did not meet the requirements. Most of the stunted and non-stunted toddlers use clean water that meets the requirements. The results show that there is a significant relationship between home sanitation that does not meet the requirements and the incidence of stunting in toddlers, but there is no significant relationship between clean water facilities and the incidence of stunting in toddlers in the Lampihong Health Center, Balangan Regency.
{"title":"Home Sanitation and Clean Water Facilities in Stunting Cases at the Lampihong Health Center Area, Balangan","authors":"Farida Heriyani, Ainun Farida, Maria Ulfah","doi":"10.20527/jbk.v19i2.17421","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17421","url":null,"abstract":"Stunting is a condition of growth failure in children under five years old (toddlers) due to chronic malnutrition and recurrent infections, especially in the first 1,000 days of life. One of the indirect causes is the availability of clean water and poor sanitation. Lampihong Community Health Center Balangan Regency is one of the areas with the highest stunting cases in South Kalimantan. This study aims to analyze the relationship between home sanitation and clean water facilities with the incidence of stunting in the Lampihong Community Health Center, Balangan Regency. The research method is analytic observational with a case control approach. The research sample consisted of 30 mothers of stunted toddlers as the case group and 30 mothers of non-stunted toddlers as the control group. Data analysis used the chi square test at a 95% confidence level. The research results showed that the majority of stunted toddlers lived in houses with unhealthy water closet, wastewater disposal and waste management that did not meet the requirements. Most of the stunted and non-stunted toddlers use clean water that meets the requirements. The results show that there is a significant relationship between home sanitation that does not meet the requirements and the incidence of stunting in toddlers, but there is no significant relationship between clean water facilities and the incidence of stunting in toddlers in the Lampihong Health Center, Balangan Regency.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17386
Saftia Aryzki, Dwi Rizki Febrianti
Indonesia itself as a tropical country has many plants that can be used as biolarvicides, one of which is the ramania plant (Bouea macrophylla Griffith). Ramania fruit epidermis contains secondary metabolites such as flavonoids, saponins, phenolic tannins, alcohol, steroids and terpenoids where these compounds have a larvicidal effect. The purpose of this study was to determine the activity of the ethanol extract of the epidermis of the ramania fruit as a biolarvicidal Mosquito larvae from the LC50 value. This research is a laboratory experimental research. The treatment concentrations used in this study were 25 ppm, 50 ppm, and 100 ppm. Temephos 1% was used as a positive control. Concentrations were then tested on 20 larvae instar III. The results of SPSS analysis with a significance of <0.05 showed that there was an effect of treatment on the number of larvae deaths, where the results of Tuckey analysis showed that concentrations of 50 ppm and 100 ppm and Temephos 1% showed differences. which means the number of deaths of test larvae. The results showed that the ethanol extract of ramania rind of ramania fruit (Bouea macrophylla Griffith) was effective as a biolarvicidal mosquito larvae. The results of probit analysis showed that the LC50 of ethanol extract of ramania rind against larvae was 20,844 ppm which is a low toxic group in aquatic environments.
{"title":"Effectiveness of Ramania Leaves (Bouea macrophylla Griffith) from South Kalimantan as a Mosquito Larvae Biolarvicidal","authors":"Saftia Aryzki, Dwi Rizki Febrianti","doi":"10.20527/jbk.v19i2.17386","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17386","url":null,"abstract":"Indonesia itself as a tropical country has many plants that can be used as biolarvicides, one of which is the ramania plant (Bouea macrophylla Griffith). Ramania fruit epidermis contains secondary metabolites such as flavonoids, saponins, phenolic tannins, alcohol, steroids and terpenoids where these compounds have a larvicidal effect. The purpose of this study was to determine the activity of the ethanol extract of the epidermis of the ramania fruit as a biolarvicidal Mosquito larvae from the LC50 value. This research is a laboratory experimental research. The treatment concentrations used in this study were 25 ppm, 50 ppm, and 100 ppm. Temephos 1% was used as a positive control. Concentrations were then tested on 20 larvae instar III. The results of SPSS analysis with a significance of <0.05 showed that there was an effect of treatment on the number of larvae deaths, where the results of Tuckey analysis showed that concentrations of 50 ppm and 100 ppm and Temephos 1% showed differences. which means the number of deaths of test larvae. The results showed that the ethanol extract of ramania rind of ramania fruit (Bouea macrophylla Griffith) was effective as a biolarvicidal mosquito larvae. The results of probit analysis showed that the LC50 of ethanol extract of ramania rind against larvae was 20,844 ppm which is a low toxic group in aquatic environments.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to determine the effect of self-management with family coaching on reducing blood glucose levels in patients with diabetes mellitus. This study used a quantitative method with a pre-experimental approach with a total sample of 30 people using a purposive sampling technique. The results of this study indicate that self-management with family coaching contributes to a decrease in blood glucose levels in diabetes mellitus patients with a significant value of p = 0.000 > 0.05. It can be concluded that self-management with family e coaching has an effect on reducing blood glucose levels in patients with diabetes mellitus. For future researchers, it is hoped that they can develop Android-based applications for family e-coaching.
{"title":"The Effect of Self Management Through Family E - Coaching on Decreased Blood Glucose Levels in Diabetes Mellitus Patients","authors":"Tut Handayani, Indargairi Indargairi, Alamsyah Alamsyah","doi":"10.20527/jbk.v19i2.17422","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17422","url":null,"abstract":"The purpose of this study was to determine the effect of self-management with family coaching on reducing blood glucose levels in patients with diabetes mellitus. This study used a quantitative method with a pre-experimental approach with a total sample of 30 people using a purposive sampling technique. The results of this study indicate that self-management with family coaching contributes to a decrease in blood glucose levels in diabetes mellitus patients with a significant value of p = 0.000 > 0.05. It can be concluded that self-management with family e coaching has an effect on reducing blood glucose levels in patients with diabetes mellitus. For future researchers, it is hoped that they can develop Android-based applications for family e-coaching.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17388
Wim Zweiryadinda, Tri Oktaviyantini, Wijaya Kusuma
Patients with chronic kidney disease (CKD) undergoing routine hemodialysis (HD) may experience psychiatric comorbidities like depression. The coping mechanism is thought to be associated with the emergence of depression in patients with CKD. This cross-sectional study examines the association between coping mechanisms and depression in CKD patients undergoing routine HD therapy at Dr. Moewardi Hospital, Surakarta. Brief COPE and Hospital Anxiety and Depression Scale (HADS) questionnaire were used as study instruments. The result showed that 29 (78.38%) research subjects used adaptive coping, while 8 (21.62%) used maladaptive coping. There are 13 (35%) participants with mild depression. Spearman’s rank correlation showed a strong negative correlation between adaptive coping mechanisms and the severity of depression in CKD patients undergoing hemodialysis (r=-0,655; p<0,01)
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Pub Date : 2023-09-13DOI: 10.20527/jbk.v19i2.17404
Ahmad Aldi Fadillah, Mohammad Bakhriansyah, Intan Yustikasari, P. W. Nurikhwan, D. L. Adiputro
Stable angina pectoris (SAP) is an imbalance that occurs when myocardial oxygen need increases disproportionally, causing complaints of chest pain. Uncontrolled SAP can lead to a complication of heart failure (HF). Polypharmacy treatment frequently given to SAP patients with HF complications can be potentially detrimental for them. This study aims to determine the risk of adverse drug-drug interactions in SAP patients with HF complications prescribed polypharmacy. This was an analytic observational study with a cross-sectional approach using retrospective data from medical record data from 2020-2021 among hospitalized patients in cardiology ward Ulin General Hospital, Banjarmasin. Potential drug-drug interactions were determined using the Lexicomp tool from the UpToDate® site. Prevalence Odds Ratio (POR) and 95% Confidence Interval (95%CI) were determined using the Logistic Regression test at the 95% level of confidence. Twenty-four SAP patients with HF were recruited. According to its potential interactions, the most interactions were under category C (82.6%), followed by category B (11.3%) and category D (6.0%). Based on its level of severity, the most common was moderate (77.4%), followed by minor (13.0%) and major (9.5%). SAP patients with HF who were not prescribed polypharmacy had a lower risk of adverse drug-drug interactions by 64.7% compared to polypharmacy users, although it was not statistically difference (crude POR 0.353, 95% CI; 0.360-3.421; p-value = 0.369). This study shows that there is a tendency of lower risk of adverse drug-drug interactions in SAP patients with HF complication prescribed polypharmacy compared to those without polypharmacy, but the association is not statistically significant.
稳定型心绞痛（SAP）是当心肌需氧量不成比例地增加时出现的一种不平衡现象，会引起胸痛。不受控制的 SAP 可导致心力衰竭（HF）并发症。对有心力衰竭并发症的 SAP 患者经常采用多种药物治疗可能对他们不利。本研究旨在确定有心力衰竭并发症的 SAP 患者接受多种药物治疗时发生不良药物相互作用的风险。这是一项横断面分析观察性研究，使用的是2020-2021年班加罗尔马辛乌林综合医院心脏病科病房住院患者的病历回顾性数据。使用 UpToDate® 网站的 Lexicomp 工具确定潜在的药物相互作用。使用置信度为 95% 的 Logistic 回归测试确定了患病率比值 (POR) 和 95% 置信区间 (95%CI)。共招募了 24 名 SAP 高血压患者。根据其潜在的相互作用，最多的相互作用属于 C 类（82.6%），其次是 B 类（11.3%）和 D 类（6.0%）。根据其严重程度，最常见的是中度（77.4%），其次是轻度（13.0%）和重度（9.5%）。与使用多种药物的 SAP 高血压患者相比，未使用多种药物的 SAP 高血压患者发生药物间不良相互作用的风险降低了 64.7%，但并无统计学差异（粗略 POR 0.353，95% CI；0.360-3.421；P 值 = 0.369）。本研究表明，与未使用多种药物的患者相比，使用多种药物的高血压并发症 SAP 患者发生药物间不良相互作用的风险有降低的趋势，但这种关联在统计学上并不显著。
{"title":"The Risk of Adverse Drug-Drug Interactions for Stable Angina Pectoris Patients with Heart Failure Complication Prescribed Polypharmacy","authors":"Ahmad Aldi Fadillah, Mohammad Bakhriansyah, Intan Yustikasari, P. W. Nurikhwan, D. L. Adiputro","doi":"10.20527/jbk.v19i2.17404","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17404","url":null,"abstract":"Stable angina pectoris (SAP) is an imbalance that occurs when myocardial oxygen need increases disproportionally, causing complaints of chest pain. Uncontrolled SAP can lead to a complication of heart failure (HF). Polypharmacy treatment frequently given to SAP patients with HF complications can be potentially detrimental for them. This study aims to determine the risk of adverse drug-drug interactions in SAP patients with HF complications prescribed polypharmacy. This was an analytic observational study with a cross-sectional approach using retrospective data from medical record data from 2020-2021 among hospitalized patients in cardiology ward Ulin General Hospital, Banjarmasin. Potential drug-drug interactions were determined using the Lexicomp tool from the UpToDate® site. Prevalence Odds Ratio (POR) and 95% Confidence Interval (95%CI) were determined using the Logistic Regression test at the 95% level of confidence. Twenty-four SAP patients with HF were recruited. According to its potential interactions, the most interactions were under category C (82.6%), followed by category B (11.3%) and category D (6.0%). Based on its level of severity, the most common was moderate (77.4%), followed by minor (13.0%) and major (9.5%). SAP patients with HF who were not prescribed polypharmacy had a lower risk of adverse drug-drug interactions by 64.7% compared to polypharmacy users, although it was not statistically difference (crude POR 0.353, 95% CI; 0.360-3.421; p-value = 0.369). This study shows that there is a tendency of lower risk of adverse drug-drug interactions in SAP patients with HF complication prescribed polypharmacy compared to those without polypharmacy, but the association is not statistically significant.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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