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A diffuse modeling approach for embedded interfaces in linear elasticity 线性弹性中嵌入界面的扩散建模方法
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000001
Paul Hennig, Roland Maier, Daniel Peterseim, Dominik Schillinger, Barbara Verfürth, Markus Kästner

In this contribution, we present a diffuse modeling approach to embed material interfaces into nonconforming meshes with a focus on linear elasticity. For this purpose, a regularized indicator function is employed that describes the distribution of the different materials by a scalar value. The material in the resulting diffuse interface region is redefined in terms of this indicator function and recomputed by a homogenization of the adjacent material parameters. The applied homogenization method fulfills the kinematic compatibility across the interface and the static equilibrium at the interface. In addition, an hℓ-adaptive refinement strategy based on truncated hierarchical B-spline is applied to provide an appropriate and efficient approximation of the diffuse interface region. We justify mathematically and demonstrate numerically that the applied approach leads to optimal convergence rates in the far field for one-dimensional problems. A two-dimensional example illustrates that the application of the hℓ-adaptive refinement strategy allows for a clear reduction of the error in the near and far field and a good resolution of the local stress and strain fields at the interface. The use of a higher continuous B-spline basis leads to efficient computations due to the higher continuity of the diffuse interface model.

在这篇文章中,我们提出了一种漫射建模方法,将材料界面嵌入到非一致性网格中,重点是线性弹性。为此,采用正则化指标函数,用标量值描述不同材料的分布。由此产生的扩散界面区域中的材料根据该指示函数重新定义,并通过相邻材料参数的均匀化重新计算。所采用的均质化方法满足了跨界面的运动相容和界面处的静力平衡。此外,采用基于截断层次b样条的h - h自适应细化策略对扩散界面区域进行了适当有效的逼近。我们在数学上进行了论证,并在数值上证明了所采用的方法可以在远场得到一维问题的最优收敛速率。二维算例表明,应用h -自适应细化策略可以明显减小近场和远场误差,并能很好地分辨界面处的局部应力和应变场。由于扩散界面模型具有较高的连续性,因此使用较高的连续b样条基可以提高计算效率。
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引用次数: 8
Spline- and hp-basis functions of higher differentiability in the finite cell method 有限单元法中具有较高可微性的样条基和hp基函数
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000004
Stefan Kollmannsberger, Davide D'Angella, Ernst Rank, Wadhah Garhuom, Simeon Hubrich, Alexander Düster, Paolo Di Stolfo, Andreas Schröder

In this paper, the use of hp-basis functions with higher differentiability properties is discussed in the context of the finite cell method and numerical simulations on complex geometries. For this purpose, Ck hp-basis functions based on classical B-splines and a new approach for the construction of C1 hp-basis functions with minimal local support are introduced. Both approaches allow for hanging nodes, whereas the new C1 approach also includes varying polynomial degrees. The properties of the hp-basis functions are studied in several numerical experiments, in which a linear elastic problem with some singularities is discretized with adaptive refinements. Furthermore, the application of the Ck hp-basis functions based on B-splines is investigated in the context of nonlinear material models, namely hyperelasticity and elastoplasicity with finite strains.

本文在有限单元法和复杂几何的数值模拟的背景下,讨论了具有高可微性的hp基函数的应用。为此,提出了基于经典b样条的Ck hp-基函数和一种构造具有最小局部支持的C1 hp-基函数的新方法。两种方法都允许挂节点,而新的C1方法还包括不同的多项式度。本文通过数值实验研究了一类具有奇异性的线性弹性问题的性质,并对其进行了自适应离散化。此外,研究了基于b样条的Ck - hp基函数在非线性材料模型(即超弹性和有限应变弹塑性)中的应用。
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引用次数: 8
A detailed investigation of the model influencing parameters of the phase-field fracture approach 详细研究了相场断裂方法的影响参数模型
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000005
Carola Bilgen, Alena Kopaničáková, Rolf Krause, Kerstin Weinberg

Phase-field approaches to fracture are gaining popularity to compute a priori unknown crack paths. In this work the sensitivity of such phase-field approaches with respect to its model specific parameters, that is, the critical length of regularization, the degradation function and the mobility, is investigated. The susceptibility of the computed cracks to the setting of these parameters is studied for problems of linear and finite elasticity. Furthermore, the convergence properties of different solution strategies are analyzed. Monolithic and staggered solution schemes for the solution of the arising nonlinear discrete systems are studied in detail. To conclude, we demonstrate the versatility of the phase-field fracture approach in a real-world problem by comparing different simulations of conchoidal fracture using structured and unstructured meshes.

相场断裂分析方法在计算先验未知裂纹路径方面越来越受欢迎。在这项工作中,研究了这种相场方法相对于其模型特定参数的灵敏度,即正则化的临界长度,退化函数和迁移率。针对线弹性和有限弹性问题,研究了计算裂纹对这些参数设置的敏感性。进一步分析了不同解策略的收敛性。详细研究了非线性离散系统的整体解和交错解方案。最后,我们通过比较使用结构化和非结构化网格的不同贝壳状裂缝模拟,证明了相场压裂方法在现实问题中的通用性。
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引用次数: 6
Mesh adaptivity for quasi-static phase-field fractures based on a residual-type a posteriori error estimator 基于残差型后验误差估计的准静态相场裂缝网格自适应
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000003
K. Mang, M. Walloth, T. Wick, W. Wollner

In this work, we consider adaptive mesh refinement for a monolithic phase-field description for fractures in brittle materials. Our approach is based on an a posteriori error estimator for the phase-field variational inequality realizing the fracture irreversibility constraint. The key goal is the development of a reliable and efficient residual-type error estimator for the phase-field fracture model in each time-step. Based on this error estimator, error indicators for local mesh adaptivity are extracted. The proposed estimator is based on a technique known for singularly perturbed equations in combination with estimators for variational inequalities. These theoretical developments are used to formulate an adaptive mesh refinement algorithm. For the numerical solution, the fracture irreversibility is imposed using a Lagrange multiplier. The resulting saddle-point system has three unknowns: displacements, phase-field, and a Lagrange multiplier for the crack irreversibility. Several numerical experiments demonstrate our theoretical findings with the newly developed estimators and the corresponding refinement strategy.

在这项工作中,我们考虑自适应网格细化的整体相场描述脆性材料的断裂。该方法基于相场变分不等式的后验误差估计,实现了断裂不可逆性约束。关键目标是为相场裂缝模型在每个时间步长中建立一个可靠、有效的残差型误差估计器。在此误差估计的基础上,提取局部网格自适应的误差指标。所提出的估计量是基于已知的奇摄动方程与变分不等式估计量相结合的技术。这些理论发展被用于制定自适应网格细化算法。对于数值解,使用拉格朗日乘子施加断裂不可逆性。由此产生的鞍点系统有三个未知数:位移、相场和裂纹不可逆性的拉格朗日乘子。一些数值实验证明了我们用新开发的估计器和相应的改进策略所得到的理论结论。
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引用次数: 23
On computational approaches of liver lobule function and perfusion simulation 肝小叶功能的计算方法及灌注模拟
Q1 Mathematics Pub Date : 2019-05-24 DOI: 10.1002/gamm.201900016
Tim Ricken, Lena Lambers

In recent years computational models have become more important for simulating hepatic processes and investigating liver diseases in silico and so various liver models have been published. The complex behavior of biological tissue with its hierarchical structure as well as the blood perfusion through the organ have been described using different approaches and numerical techniques. This paper shows and compares numerical approaches for function and perfusion simulation recently published and compares them with a multiscale function-perfusion model using the extended theory of porous media. We focus on the description of blood perfusion and liver tissue, but also on the simulation of liver diseases or the zonation of processes in the liver. Furthermore, the selected geometry is taken into account.

近年来,计算模型在模拟肝脏过程和研究肝脏疾病方面变得越来越重要,因此各种肝脏模型已经发表。生物组织的复杂行为及其层次结构以及血液在器官中的灌注已经用不同的方法和数值技术进行了描述。本文展示和比较了最近发表的功能和灌注模拟的数值方法,并将它们与基于多孔介质扩展理论的多尺度功能灌注模型进行了比较。我们专注于血液灌注和肝脏组织的描述,但也对肝脏疾病的模拟或肝脏过程的分区。此外,还考虑了所选择的几何形状。
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引用次数: 5
A study of growth and remodeling in isotropic tissues, based on the Anand-Aslan-Chester theory of strain-gradient plasticity 基于应变梯度塑性的Anand-Aslan-Chester理论的各向同性组织生长和重塑研究
Q1 Mathematics Pub Date : 2019-05-22 DOI: 10.1002/gamm.201900015
Alfio Grillo, Salvatore Di Stefano, Ariel Ramírez-Torres, Michele Loverre

Motivated by the increasing interest of the biomechanical community towards the employment of strain-gradient theories for solving biological problems, we study the growth and remodeling of a biological tissue on the basis of a strain-gradient formulation of remodeling. Our scope is to evaluate the impact of such an approach on the principal physical quantities that determine the growth of the tissue. For our purposes, we assume that remodeling is characterized by a coarse and a fine length scale and, taking inspiration from a work by Anand, Aslan, and Chester, we introduce a kinematic variable that resolves the fine scale inhomogeneities induced by remodeling. With respect to this variable, a strain-gradient framework of remodeling is developed. We adopt this formulation in order to investigate how a tumor tissue grows and how it remodels in response to growth. In particular, we focus on a type of remodeling that manifests itself in two different, but complementary, ways: on the one hand, it finds its expression in a stress-induced reorganization of the adhesion bonds among the tumor cells, and, on the other hand, it leads to a change of shape of the cells and of the tissue, which is generally not recovered when external loads are removed. To address this situation, we resort to a generalized Bilby-Kröner-Lee decomposition of the deformation gradient tensor. We test our model on a benchmark problem taken from the literature, which we rephrase in two ways: microscale remodeling is disregarded in the first case, and accounted for in the second one. Finally, we compare and discuss the obtained numerical results.

由于生物力学界对利用应变梯度理论解决生物问题的兴趣日益浓厚,我们在应变梯度重塑公式的基础上研究了生物组织的生长和重塑。我们的范围是评估这种方法对决定组织生长的主要物理量的影响。出于我们的目的,我们假设重塑的特征是粗和细长度尺度,并从Anand, Aslan和Chester的作品中获得灵感,我们引入了一个运动学变量来解决重塑引起的细尺度不均匀性。在此基础上,建立了应变梯度重构框架。我们采用这个公式是为了研究肿瘤组织是如何生长的,以及它是如何随着生长而重塑的。我们特别关注一种以两种不同但互补的方式表现出来的重塑:一方面,它在肿瘤细胞之间的粘附键的应力诱导重组中表现出来,另一方面,它导致细胞和组织形状的变化,这种变化通常在去除外部负载后不会恢复。为了解决这种情况,我们求助于变形梯度张量的广义Bilby-Kröner-Lee分解。我们在取自文献的基准问题上测试我们的模型,我们以两种方式重新表述:在第一种情况下忽略微尺度重塑,并在第二种情况下考虑。最后,对得到的数值结果进行了比较和讨论。
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引用次数: 12
The dynamics of the skeletal muscle: A systems biophysics perspective on muscle modeling with the focus on Hill-type muscle models 骨骼肌动力学:肌肉建模的系统生物物理学观点,重点是希尔型肌肉模型
Q1 Mathematics Pub Date : 2019-05-21 DOI: 10.1002/gamm.201900013
Syn Schmitt, Michael Günther, Daniel F. B. Häufle

Skeletal muscle is one of the most fascinating and crucial ingredients of motion generation in nature. Since the beginning of science, people dedicate their life as researchers to enhance knowledge about this biological motor. Thus, the scientific knowledge about the skeletal muscle is overwhelmingly broad and detailed. This contribution collects knowledge about the active and passive dynamics of skeletal muscle. Furthermore, it highlights a special perspective in which not only the muscle itself, but also the role muscles play in the interaction with other structures is studied. The first section introduces this systems biophysics perspective, which clusters the investigation of the relations, interactions and dependencies between muscles and the other structures in the movement apparatus. In the second section, the muscles are considered in more detail by describing three approaches to muscle modeling. The third section deals with recent advances based on Hill-type models, such as, for example, the integration of mass.

骨骼肌是自然界中产生运动的最迷人和最重要的成分之一。自从有了科学,人们就把自己的一生奉献给了研究人员,以提高对这种生物运动的认识。因此,关于骨骼肌的科学知识极其广泛和详细。这一贡献收集了有关骨骼肌主动和被动动力学的知识。此外,它还突出了一个特殊的视角,不仅研究了肌肉本身,还研究了肌肉在与其他结构相互作用中的作用。第一部分介绍了这个系统生物物理学的观点,它聚集了肌肉和运动器械中其他结构之间的关系、相互作用和依赖关系的调查。在第二节中,通过描述肌肉建模的三种方法,更详细地考虑了肌肉。第三部分讨论了基于hill型模型的最新进展,例如质量的集成。
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引用次数: 12
A generalized inelastic modeling concept for soft fibrous tissues 软纤维组织的广义非弹性建模概念
Q1 Mathematics Pub Date : 2019-05-14 DOI: 10.1002/gamm.201900014
Markus Hillgärtner, Kevin Linka, Mikhail Itskov

This contribution proposes a multiscale modeling approach, ranging from the macromolecular behavior of tropocollagen over collagen fibrils and the interfibrillar matrix up to bundles of collagen fibers. Two damage mechanisms are described: intramolecular damage inside the tropocollagen molecules based on a permanent opening of the triple helical conformation and damage in the interfibrillar matrix restricting the recovery of interfibrillar sliding. Both intramolecular and interfibrillar damage is considered as a probabilistic process based on detachment of adhesive bonds, where the probability of failure depends on the full load history of the bond. The presented modeling concept is based on generalized assumptions valid for most soft fibrous tissues, and can therefore be applied for a variety of tissues and load-cases. The final constitutive equations are validated against recent experimental data from uniaxial tension tests of rat tail tendon. All utilized material constants have a clear physical interpretation.

这一贡献提出了一种多尺度建模方法,从胶原原纤维和纤维间基质上的胶原蛋白的大分子行为到胶原纤维束。描述了两种损伤机制:基于三螺旋构象永久开放的原胶原分子内部的分子内损伤和限制纤维间滑动恢复的纤维间基质的损伤。分子内损伤和纤维间损伤都被认为是一个基于粘接键脱离的概率过程,其中失败的概率取决于键的全部载荷历史。所提出的建模概念是基于对大多数软纤维组织有效的广义假设,因此可以应用于各种组织和载荷情况。最后的本构方程与最近的大鼠尾腱单轴拉伸试验数据进行了验证。所有使用的材料常数都有明确的物理解释。
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引用次数: 1
Biomechanics of the tricuspid annulus: A review of the annulus' in vivo dynamics with emphasis on ovine data 三尖瓣环的生物力学:回顾环的体内动力学,重点是羊的数据
Q1 Mathematics Pub Date : 2019-05-14 DOI: 10.1002/gamm.201900012
Manuel K. Rausch, Mrudang Mathur, William D. Meador
The tricuspid annulus forms the boundary between the tricuspid valve leaflets and their surrounding perivalvular tissue of the right atrioventricular junction. Its shape changes throughout the cardiac cycle in response to the forces from the contracting right heart myocardium and the blood‐valve interaction. Alterations to annular shape and dynamics in disease lead to valvular dysfunctions such as tricuspid regurgitation from which millions of patients suffer. Successful treatment of such dysfunction requires an in‐depth understanding of the normal shape and dynamics of the tricuspid annulus and of the changes following disease and subsequent repair. In this manuscript we review what we know about the shape and dynamics of the normal tricuspid annulus and about the effects of both disease and repair based on noninvasive imaging studies and invasive fiduciary marker‐based studies. We further show, by means of ovine data, that detailed engineering analyses of the tricuspid annulus provide regionally resolved insight into the kinematics of the annulus which would remain hidden if limiting analyses to simple geometric metrics.
三尖瓣环形成了三尖瓣小叶与其周围右房室交界瓣周组织之间的边界。在整个心脏周期中,它的形状会随着右心肌收缩和血瓣膜相互作用的作用力而改变。疾病中环形形状和动力学的改变导致瓣膜功能障碍,如三尖瓣反流,数百万患者因此而受苦。成功治疗这种功能障碍需要深入了解三尖瓣环的正常形状和动力学,以及疾病和随后的修复后的变化。在这篇文章中,我们回顾了我们所知道的关于正常三尖瓣环的形状和动力学,以及基于非侵入性成像研究和侵入性信托标志物研究的疾病和修复的影响。我们进一步表明,通过羊的数据,详细的工程分析三尖瓣环提供区域解决洞察环的运动学,这将保持隐藏,如果限制分析简单的几何指标。
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引用次数: 6
Assessment and design of an engineering structure with polymorphic uncertainty quantification 基于多态不确定性量化的工程结构评估与设计
Q1 Mathematics Pub Date : 2019-04-22 DOI: 10.1002/gamm.201900009
Iason Papaioannou, Marco Daub, Martin Drieschner, Fabian Duddeck, Max Ehre, Lukas Eichner, Martin Eigel, Marco Götz, Wolfgang Graf, Lars Grasedyck, Robert Gruhlke, Dietmar Hömberg, Michael Kaliske, Dieter Moser, Yuri Petryna, Daniel Straub

Engineers are faced with the challenge of supporting decision making under uncertainty. Engineering decisions often depend on model-based predictions of the performance of the engineering system of interest. Input uncertainties of models can be categorized into two distinct types: aleatory (random/irreducible) or epistemic (reducible). Polymorphic uncertainty quantification (UQ) can be used to treat aleatory and epistemic uncertainties in a unified framework. The polymorphic UQ framework employs probability theory to model aleatory variables and alternative approaches (interval, fuzzy, Bayesian probabilistic, and combinations thereof) to model epistemic variables. This paper compares different polymorphic UQ approaches with respect to their ability to support a simple engineering decision. The comparison is based on a test-bed example, whereby aleatory variables are defined in terms of probability distributions and epistemic variables are described based on limited information (sparse data or intervals). Two challenges related to common engineering decisions (safety assessment and reliability-based design) serve as a basis for the comparison. Five independent research groups applied different models to describe the epistemic parameters based on a subjective interpretation of the given information. The comparison of the results reveals a strong influence of both the subjective choices on the models of the epistemic variables and the chosen basis for assessing the performance of the structure on the obtained decision outcomes.

工程师面临着在不确定条件下支持决策的挑战。工程决策通常依赖于对感兴趣的工程系统性能的基于模型的预测。模型的输入不确定性可以分为两种不同的类型:任意(随机/不可约)或认知(可约)。多态不确定性量化(UQ)可以在一个统一的框架中处理偶然性和认识性不确定性。多态UQ框架采用概率论对偶然性变量建模,并采用替代方法(区间、模糊、贝叶斯概率及其组合)对认知变量建模。本文比较了不同的多态UQ方法在支持简单工程决策方面的能力。这种比较是基于一个测试平台的例子,在这个例子中,随机变量是根据概率分布来定义的,而认知变量是基于有限的信息(稀疏数据或间隔)来描述的。与常见工程决策相关的两个挑战(安全评估和基于可靠性的设计)作为比较的基础。五个独立的研究小组应用不同的模型来描述基于对给定信息的主观解释的认知参数。结果的比较揭示了主观选择对认知变量模型的强烈影响,以及评估结构性能的选择基础对获得的决策结果的强烈影响。
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引用次数: 14
期刊
GAMM Mitteilungen
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