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A generalized inelastic modeling concept for soft fibrous tissues 软纤维组织的广义非弹性建模概念
Q1 Mathematics Pub Date : 2019-05-14 DOI: 10.1002/gamm.201900014
Markus Hillgärtner, Kevin Linka, Mikhail Itskov

This contribution proposes a multiscale modeling approach, ranging from the macromolecular behavior of tropocollagen over collagen fibrils and the interfibrillar matrix up to bundles of collagen fibers. Two damage mechanisms are described: intramolecular damage inside the tropocollagen molecules based on a permanent opening of the triple helical conformation and damage in the interfibrillar matrix restricting the recovery of interfibrillar sliding. Both intramolecular and interfibrillar damage is considered as a probabilistic process based on detachment of adhesive bonds, where the probability of failure depends on the full load history of the bond. The presented modeling concept is based on generalized assumptions valid for most soft fibrous tissues, and can therefore be applied for a variety of tissues and load-cases. The final constitutive equations are validated against recent experimental data from uniaxial tension tests of rat tail tendon. All utilized material constants have a clear physical interpretation.

这一贡献提出了一种多尺度建模方法,从胶原原纤维和纤维间基质上的胶原蛋白的大分子行为到胶原纤维束。描述了两种损伤机制:基于三螺旋构象永久开放的原胶原分子内部的分子内损伤和限制纤维间滑动恢复的纤维间基质的损伤。分子内损伤和纤维间损伤都被认为是一个基于粘接键脱离的概率过程,其中失败的概率取决于键的全部载荷历史。所提出的建模概念是基于对大多数软纤维组织有效的广义假设,因此可以应用于各种组织和载荷情况。最后的本构方程与最近的大鼠尾腱单轴拉伸试验数据进行了验证。所有使用的材料常数都有明确的物理解释。
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引用次数: 1
Biomechanics of the tricuspid annulus: A review of the annulus' in vivo dynamics with emphasis on ovine data 三尖瓣环的生物力学:回顾环的体内动力学,重点是羊的数据
Q1 Mathematics Pub Date : 2019-05-14 DOI: 10.1002/gamm.201900012
Manuel K. Rausch, Mrudang Mathur, William D. Meador
The tricuspid annulus forms the boundary between the tricuspid valve leaflets and their surrounding perivalvular tissue of the right atrioventricular junction. Its shape changes throughout the cardiac cycle in response to the forces from the contracting right heart myocardium and the blood‐valve interaction. Alterations to annular shape and dynamics in disease lead to valvular dysfunctions such as tricuspid regurgitation from which millions of patients suffer. Successful treatment of such dysfunction requires an in‐depth understanding of the normal shape and dynamics of the tricuspid annulus and of the changes following disease and subsequent repair. In this manuscript we review what we know about the shape and dynamics of the normal tricuspid annulus and about the effects of both disease and repair based on noninvasive imaging studies and invasive fiduciary marker‐based studies. We further show, by means of ovine data, that detailed engineering analyses of the tricuspid annulus provide regionally resolved insight into the kinematics of the annulus which would remain hidden if limiting analyses to simple geometric metrics.
三尖瓣环形成了三尖瓣小叶与其周围右房室交界瓣周组织之间的边界。在整个心脏周期中,它的形状会随着右心肌收缩和血瓣膜相互作用的作用力而改变。疾病中环形形状和动力学的改变导致瓣膜功能障碍,如三尖瓣反流,数百万患者因此而受苦。成功治疗这种功能障碍需要深入了解三尖瓣环的正常形状和动力学,以及疾病和随后的修复后的变化。在这篇文章中,我们回顾了我们所知道的关于正常三尖瓣环的形状和动力学,以及基于非侵入性成像研究和侵入性信托标志物研究的疾病和修复的影响。我们进一步表明,通过羊的数据,详细的工程分析三尖瓣环提供区域解决洞察环的运动学,这将保持隐藏,如果限制分析简单的几何指标。
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引用次数: 6
Assessment and design of an engineering structure with polymorphic uncertainty quantification 基于多态不确定性量化的工程结构评估与设计
Q1 Mathematics Pub Date : 2019-04-22 DOI: 10.1002/gamm.201900009
Iason Papaioannou, Marco Daub, Martin Drieschner, Fabian Duddeck, Max Ehre, Lukas Eichner, Martin Eigel, Marco Götz, Wolfgang Graf, Lars Grasedyck, Robert Gruhlke, Dietmar Hömberg, Michael Kaliske, Dieter Moser, Yuri Petryna, Daniel Straub

Engineers are faced with the challenge of supporting decision making under uncertainty. Engineering decisions often depend on model-based predictions of the performance of the engineering system of interest. Input uncertainties of models can be categorized into two distinct types: aleatory (random/irreducible) or epistemic (reducible). Polymorphic uncertainty quantification (UQ) can be used to treat aleatory and epistemic uncertainties in a unified framework. The polymorphic UQ framework employs probability theory to model aleatory variables and alternative approaches (interval, fuzzy, Bayesian probabilistic, and combinations thereof) to model epistemic variables. This paper compares different polymorphic UQ approaches with respect to their ability to support a simple engineering decision. The comparison is based on a test-bed example, whereby aleatory variables are defined in terms of probability distributions and epistemic variables are described based on limited information (sparse data or intervals). Two challenges related to common engineering decisions (safety assessment and reliability-based design) serve as a basis for the comparison. Five independent research groups applied different models to describe the epistemic parameters based on a subjective interpretation of the given information. The comparison of the results reveals a strong influence of both the subjective choices on the models of the epistemic variables and the chosen basis for assessing the performance of the structure on the obtained decision outcomes.

工程师面临着在不确定条件下支持决策的挑战。工程决策通常依赖于对感兴趣的工程系统性能的基于模型的预测。模型的输入不确定性可以分为两种不同的类型:任意(随机/不可约)或认知(可约)。多态不确定性量化(UQ)可以在一个统一的框架中处理偶然性和认识性不确定性。多态UQ框架采用概率论对偶然性变量建模,并采用替代方法(区间、模糊、贝叶斯概率及其组合)对认知变量建模。本文比较了不同的多态UQ方法在支持简单工程决策方面的能力。这种比较是基于一个测试平台的例子,在这个例子中,随机变量是根据概率分布来定义的,而认知变量是基于有限的信息(稀疏数据或间隔)来描述的。与常见工程决策相关的两个挑战(安全评估和基于可靠性的设计)作为比较的基础。五个独立的研究小组应用不同的模型来描述基于对给定信息的主观解释的认知参数。结果的比较揭示了主观选择对认知变量模型的强烈影响,以及评估结构性能的选择基础对获得的决策结果的强烈影响。
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引用次数: 14
Challenges of order reduction techniques for problems involving polymorphic uncertainty 涉及多态不确定性问题的降阶技术的挑战
Q1 Mathematics Pub Date : 2019-04-15 DOI: 10.1002/gamm.201900011
Dmytro Pivovarov, Kai Willner, Paul Steinmann, Stephan Brumme, Michael Müller, Tarin Srisupattarawanit, Georg-Peter Ostermeyer, Carla Henning, Tim Ricken, Steffen Kastian, Stefanie Reese, Dieter Moser, Lars Grasedyck, Jonas Biehler, Martin Pfaller, Wolfgang Wall, Thomas Kohlsche, Otto von Estorff, Robert Gruhlke, Martin Eigel, Max Ehre, Iason Papaioannou, Daniel Straub, Sigrid Leyendecker

Modeling of mechanical systems with uncertainties is extremely challenging and requires a careful analysis of a huge amount of data. Both, probabilistic modeling and nonprobabilistic modeling require either an extremely large ensemble of samples or the introduction of additional dimensions to the problem, thus, resulting also in an enormous computational cost growth. No matter whether the Monte-Carlo sampling or Smolyak's sparse grids are used, which may theoretically overcome the curse of dimensionality, the system evaluation must be performed at least hundreds of times. This becomes possible only by using reduced order modeling and surrogate modeling. Moreover, special approximation techniques are needed to analyze the input data and to produce a parametric model of the system's uncertainties. In this paper, we describe the main challenges of approximation of uncertain data, order reduction, and surrogate modeling specifically for problems involving polymorphic uncertainty. Thereby some examples are presented to illustrate the challenges and solution methods.

具有不确定性的机械系统建模极具挑战性,需要对大量数据进行仔细分析。概率建模和非概率建模都需要一个非常大的样本集合,或者向问题引入额外的维度,因此,也会导致巨大的计算成本增长。无论使用蒙特卡罗采样还是Smolyak的稀疏网格,理论上都可以克服维数的诅咒,系统评估必须至少进行数百次。这只能通过使用简化顺序建模和代理建模来实现。此外,需要特殊的近似技术来分析输入数据并产生系统不确定性的参数模型。在本文中,我们描述了不确定数据的近似、阶数约简和代理建模的主要挑战,特别是涉及多态不确定性的问题。因此,通过实例说明了面临的挑战和解决方法。
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引用次数: 6
Multifidelity approaches for uncertainty quantification 不确定度量化的多保真度方法
Q1 Mathematics Pub Date : 2019-04-05 DOI: 10.1002/gamm.201900008
Jonas Biehler, Markus Mäck, Jonas Nitzler, Michael Hanss, Phaedon-Stelios Koutsourelakis, Wolfgang A. Wall

The aim of this paper is to give an overview of different multifidelity uncertainty quantification (UQ) schemes. Therefore, different views on multifidelity UQ approaches from a frequentist, Bayesian, and possibilistic perspective are provided and recent developments are discussed. Differences as well as similarities between the methods are highlighted and strategies to construct low-fidelity models are explained. In addition, two state-of-the-art examples to showcase the capabilities of these methods and the tremendous reduction of computational costs that can be achieved when using these approaches are provided.

本文的目的是概述不同的多保真度不确定性量化(UQ)方案。因此,从频率论、贝叶斯和可能性的角度提供了对多保真度UQ方法的不同观点,并讨论了最近的发展。强调了这些方法之间的异同,并解释了构建低保真模型的策略。此外,还提供了两个最先进的示例,以展示这些方法的功能以及使用这些方法时可以实现的计算成本的巨大降低。
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引用次数: 12
Analysis of polymorphic data uncertainties in engineering applications 工程应用中多态数据不确定性分析
Q1 Mathematics Pub Date : 2019-03-28 DOI: 10.1002/gamm.201900010
Martin Drieschner, Hermann G. Matthies, Truong-Vinh Hoang, Bojana V. Rosić, Tim Ricken, Carla Henning, Georg-Peter Ostermeyer, Michael Müller, Stephan Brumme, Tarin Srisupattarawanit, Kerstin Weinberg, Tim F. Korzeniowski

In this contribution, several case studies with data uncertainties are presented which have been performed in individual projects as part of the DFG (German Research Foundation) Priority Programme SPP 1886 “Polymorphic uncertainty modelling for the numerical design of structures.” In all case studies numerical models with uncertainties are derived from engineering problems describing concepts for handling and incorporating measurement data, either of model input parameters or of the system response. The first case study deals with polymorphic uncertain data based on computer tomographic scans with respect to air voids which are acquired, simplified and integrated in numerical models of adhesive bonds. In the second case study, the variation sensitivity analysis is presented to provide suitable prior knowledge for numerical soil analyses, for example, in order to reduce required input data. The uncertainty in friction processes is treated in case study 3 whereby measurement data are used in data driven methods to improve the numerical predictions. In case study 4, the failure behavior of die-cast window hinges, which is affected by an uncertain initial pore distribution, is investigated by means of a Markov chain approach. In the last two case studies, mathematical methods of statistical inference and updating algorithms for uncertainty models are shown. Due to the heterogeneous spectrum of problems, a generalized strategy for data modeling, acquisition, and assimilation is developed and applied on each case study.

在这篇文章中,介绍了几个具有数据不确定性的案例研究,这些研究是作为DFG(德国研究基金会)优先计划SPP 1886“结构数值设计的多态不确定性建模”的一部分,在个别项目中进行的。在所有的案例研究中,具有不确定性的数值模型都是从工程问题中导出的,这些工程问题描述了处理和合并测量数据的概念,无论是模型输入参数还是系统响应。第一个案例研究处理基于计算机层析扫描的关于空气空隙的多态不确定数据,这些数据被获取、简化并集成到黏着键的数值模型中。在第二个案例研究中,变异敏感性分析为数值土壤分析提供了合适的先验知识,例如,为了减少所需的输入数据。在案例研究3中处理摩擦过程中的不确定性,其中测量数据用于数据驱动方法以改进数值预测。在案例研究4中,采用马尔可夫链方法研究了不确定初始孔隙分布对压铸窗铰链破坏行为的影响。在最后两个案例中,给出了统计推理的数学方法和不确定性模型的更新算法。由于问题的异质性,开发了一种用于数据建模、获取和同化的通用策略,并将其应用于每个案例研究。
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引用次数: 3
Development of fuzzy probability based random fields for the numerical structural design 基于模糊概率随机场的数值结构设计
Q1 Mathematics Pub Date : 2019-03-21 DOI: 10.1002/gamm.201900004
Friedemann N. Schietzold, Albrecht Schmidt, Mona M. Dannert, Amelie Fau, Rudolfo M. N. Fleury, Wolfgang Graf, Michael Kaliske, Carsten Könke, Tom Lahmer, Udo Nackenhorst

In structural analysis with multivariate random fields, the underlying distribution functions, the autocorrelations, and the crosscorrelations require an extensive quantification. While those parameters are difficult to measure in experiments, a lack of knowledge is included. Therefore, polymorphic uncertainty models are attained by involving uncertainty models with epistemic characteristic for the quantification of the stochastic models in this contribution. Three extensions for random fields with polymorphic uncertainty modeling are introduced. Interval probability based random fields, fuzzy probability based random fields, and structural dependent autocorrelations for random fields are shown. Applications for engineering problems are shown for each extension, where uncertainty analysis of structures with different materials is performed. In this contribution, a damage simulation of a concrete beam with interval valued parametrization of stochastic models, an application for porous media in a multiphysical structural analysis with fuzzy valued parametrization and an uncertainty analysis with structural dependent autocorrelations for timber structures are presented.

在多变量随机场的结构分析中,潜在的分布函数、自相关和相互关系需要广泛的量化。虽然这些参数很难在实验中测量,但缺乏知识也包括在内。因此,本文通过引入具有认知特征的不确定性模型来量化随机模型,从而获得多态不确定性模型。介绍了随机场多态不确定性建模的三种扩展。给出了基于区间概率的随机场、基于模糊概率的随机场以及随机场的结构相关自相关性。每个扩展都显示了工程问题的应用,其中对不同材料的结构进行了不确定性分析。在这篇贡献中,介绍了用随机模型的区间值参数化对混凝土梁进行损伤模拟,用模糊值参数化对多孔介质在多物理结构分析中的应用,以及用结构相关自相关性对木结构进行不确定性分析。
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引用次数: 16
Numerical studies of earth structure assessment via the theory of porous media using fuzzy probability based random field material descriptions 基于模糊概率随机场材料描述的多孔介质理论土结构评价数值研究
Q1 Mathematics Pub Date : 2019-03-21 DOI: 10.1002/gamm.201900007
Albrecht Schmidt, Carla Henning, Swetlana Herbrandt, Carsten Könke, Katja Ickstadt, Tim Ricken, Tom Lahmer

To account for the natural variability of material parameters in multiphasic and hydro-mechanical coupled finite element analyses of soil and earth structure applications, the use of probabilistic methods may be effective. Here, selecting the appropriate soil auto-correlation functions for random field realizations plays an essential role. In a joint study, the general influence of auto-correlation lengths on the results of strongly coupled models is determined. Subsequently, a polymorphic approach using fuzzy probability based random fields is used to capture the solution space for fuzzy auto-correlation lengths. To adequately describe the behavior of the soil the theory of porous media is implemented, which uses a homogenization approach for the multiple phases on the soil microstructure. Its foundations and the differentiated methods used for the polymorphic uncertainty quantification are explained in this contribution. Based on two representative examples, the requirements and advantages of a polymorphic uncertainty model are worked out30.

考虑到材料参数的自然变异性多相和水-机械耦合有限元分析的土壤和地球结构的应用,使用概率方法可能是有效的。在这里,选择合适的土壤自相关函数实现随机场起着至关重要的作用。在一项联合研究中,确定了自相关长度对强耦合模型结果的一般影响。随后,采用基于模糊概率随机场的多态方法捕获模糊自相关长度的解空间。为了充分地描述土壤的行为,实施了多孔介质理论,该理论对土壤微观结构的多相使用了均匀化方法。本文阐述了多态不确定度定量的基础和不同的方法。通过两个典型实例,分析了多态不确定性模型的要求和优点。
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引用次数: 11
Optimization with constraints considering polymorphic uncertainties 考虑多态不确定性约束的优化
Q1 Mathematics Pub Date : 2019-03-12 DOI: 10.1002/gamm.201900005
Markus Mäck, Ismail Caylak, Philipp Edler, Steffen Freitag, Michael Hanss, Rolf Mahnken, Günther Meschke, Eduard Penner

In this contribution, a numerical design strategy for the optimization under polymorphic uncertainty is introduced and applied to a self-weight minimization of a framework structure. The polymorphic uncertainty, which affects the constraint function of the optimization problem, is thereby modeled in terms of stochastic variables, fuzzy sets, and intervals to account for variability, imprecision and insufficient information. The stochastic quantities are computed using polynomial chaos expansion resulting in a purely fuzzy-valued formulation of the constraint functions which can be computed using α-cut optimization. Afterward, the constraint function can be interpreted in a possibilistic manner, resulting in a flexible formulation to include expert knowledge and to achieve a robust design.

本文介绍了一种多态不确定性优化的数值设计策略,并将其应用于框架结构的自重最小化。多态不确定性影响优化问题的约束函数,因此用随机变量、模糊集和区间来建模,以解释可变性、不精确和信息不足。随机量的计算采用多项式混沌展开,得到约束函数的纯模糊值表达式,可以用α-切优化计算。然后,约束函数可以以可能性的方式解释,从而产生灵活的公式,以包含专家知识并实现稳健设计。
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引用次数: 8
Polymorphic uncertainty modelling for numerical design of structures 结构数值设计的多态不确定性建模
Q1 Mathematics Pub Date : 2019-03-11 DOI: 10.1002/gamm.201900003
Michael Kaliske, Wolfgang Graf
The numerical analysis and design of structures are currently dominated by deterministic thinking and methods. Deterministic modelling of the reality indicates preciseness and safety, while on contrast all available information and data are characterized by uncertainty (variability, imprecision, incompleteness), which cannot be neglected to represent a holistic point of view. Main goal of the DFG Priority Programme “Polymorphic uncertainty modelling for numerical design of structures” (SPP 1886) is the development of methods for the numerical simulation and design of structures under consideration of uncertainty in data and information. On the basis of polymorphic uncertainty modelling, the description of different kinds of uncertainty is realized. Engineering solutions are designed with respect to inherent robustness and flexibility as essential features for a faultless life of structures and systems at uncertain and changing conditions. An implementation of these features in a structure or system requires a comprehensive consideration of uncertainty in the model parameters and environmental and man imposed loads as well as other types of intrinsic and epistemic uncertainties. Numerical design of structures should be robust with respect to (spatial and time dependent) uncertainties inherently present in resistance of materials, boundary conditions etc. This feature requires the availability of a reliable numerical analysis, assessment, and prediction of the lifecycle of a structure taking explicitly into account the effect of unavoidable uncertainties. Challenges in this context involve, for example, limited information, human factors, subjectivity and experience, linguistic assessments, imprecise measurements, dubious information, unclear physics etc. Because of the polymorphic nature and characteristic of the available information, both probabilistic and set-theoretical approaches are relevant for solutions. SPP 1886 brings together researchers, scholarly persons, and practicing engineers concerned with various forms of advanced engineering designs. Recent developments of numerical methods in the field of engineering design, which include a comprehensive consideration of uncertainty and associated efficient analysis techniques, such as advanced Monte Carlo simulation, meta-model approximations, and high performance computing strategies are explicitly promoted. These approaches may involve imprecise probabilities, interval methods, fuzzy methods, and further concepts. The contributions may address specific technical or mathematical details, conceptual developments and design strategies, individual solutions, and also provide overviews and comparative studies. Particular attention is paid to practical applicability of the methods in engineering. Besides the application of the involved engineering sciences, “real world” scenarios are considered. The distinction between early stage of design and final design is significant. Starting in September 2
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引用次数: 0
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