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Weakly symmetric stress equilibration for hyperelastic material models 超弹性材料模型的弱对称应力平衡
Q1 Mathematics Pub Date : 2019-09-06 DOI: 10.1002/gamm.202000007
Fleurianne Bertrand, Marcel Moldenhauer, Gerhard Starke

A stress equilibration procedure for hyperelastic material models is proposed and analyzed in this paper. Based on the displacement-pressure approximation computed with a stable finite element pair, it constructs, in a vertex-patch-wise manner, an H(div)-conforming approximation to the first Piola-Kirchhoff stress. This is done in such a way that its associated Cauchy stress is weakly symmetric in the sense that its antisymmetric part is zero tested against continuous piecewise linear functions. Our main result is the identification of the subspace of test functions perpendicular to the range of the local equilibration system on each patch which turn out to be rigid body modes associated with the current configuration. Momentum balance properties are investigated analytically and numerically and the resulting stress reconstruction is shown to provide improved results for surface traction forces by computational experiments.

本文提出并分析了超弹性材料模型的应力平衡过程。以稳定有限元对计算的位移-压力近似为基础,以顶点补丁方式构造了第一Piola-Kirchhoff应力的H(div)符合近似。这是这样做的,它的相关柯西应力是弱对称的,从某种意义上说,它的反对称部分是零,对连续分段线性函数进行测试。我们的主要结果是确定了垂直于每个斑块上局部平衡系统范围的测试函数的子空间,这些子空间被证明是与当前构型相关的刚体模态。对动量平衡特性进行了分析和数值研究,并通过计算实验证明了所得到的应力重建对表面牵引力的计算结果有所改善。
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引用次数: 6
Recent topics in biomechanics and mechanobiology 生物力学和力学生物学的最新主题
Q1 Mathematics Pub Date : 2019-09-05 DOI: 10.1002/gamm.201900017
Alexander E. Ehret, Markus Böl
Biomechanics may be seen as an independent discipline of research with its own methods, approaches, and a very long history—questions related to the functioning of living matter have preoccupied philosophers and scientists for millennia, in fact. Notwithstanding, it was continuously advanced by the theories and techniques established for classical engineering materials. Both the specific developments and those adopted and adapted from other mechanical disciplines render biomechanics a continuously evolving field until today. The progress in biomechanical research also profits from the advances in other fields, including instrumentation and techniques for experimental analyses and, in the recent decades, particularly computational science. The new insights gained from experiments serve to continuously refine models and to reconsider problems. The available computational power allows the inclusion of the increasing amount and detail of information in models of ever-growing complexity. In about the last two decades mechanobiology has emerged as an independent discipline, yet complementary to biomechanics in many aspects. Unravelling the relations between mechanical loads and the cells' biological response requires a deep understanding of cell and tissue biology, and thus represents a multidisciplinary task. Accordingly, the corresponding model formulations need to couple the mechanical field quantities with those of other physical disciplines and with the kinetics of biochemical reactions to integrate mechanics in the complex pathways of biological systems. Evidently, such deep understanding of the mechanobiological processes may help shedding light on dysfunctions and pathological situations, and also biomechanical research has incessantly been driven by medical questions from its infancy until today. Both biomechanics and mechanobiology, but in particular the joint disciplines can therefore be considered as life sciences able to face more and more detailed research problems. Concomitant with the emerging complex questions are changes in the research strategies from general to specific aspects, from singleto multiscale approaches, from monoto multiphysics problems, and from isolated problem considerations to systems approaches. With the issues 3 and 4 of this volume of the GAMM-Mitteilungen, we are very glad to present seven contributions that reflect these recent trends and their advances in biomechanics and mechanobiology. Issue 3 contains three overview-oriented articles: the article by S. Brandstaeter, S. L. Fuchs, R. C. Aydin, and C. J. Cyron presents stomach biomechanics as an emerging topic and highlights challenges. The work by M. K. Rausch, M. Mathur, and W. D. Meador gives deep insight into the biomechanics of the tricuspid annulus under healthy, diseased and repaired conditions. S. Schmitt, M. Günther, and D. F. B. Häufle in their article provide a new view on muscle models as biophysical systems. Issue 4 is dedicated to specific modelin
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引用次数: 0
Three-field mixed finite element formulations for gradient elasticity at finite strains 有限应变下梯度弹性的三场混合有限元公式
Q1 Mathematics Pub Date : 2019-08-30 DOI: 10.1002/gamm.202000002
Johannes Riesselmann, Jonas Wilhelm Ketteler, Mira Schedensack, Daniel Balzani

Gradient elasticity formulations have the advantage of avoiding geometry-induced singularities and corresponding mesh dependent finite element solution as apparent in classical elasticity formulations. Moreover, through the gradient enrichment the modeling of a scale-dependent constitutive behavior becomes possible. In order to remain C0 continuity, three-field mixed formulations can be used. Since so far in the literature these only appear in the small strain framework, in this contribution formulations within the general finite strain hyperelastic setting are investigated. In addition to that, an investigation of the inf sup condition is conducted and unveils a lack of existence of a stable solution with respect to the L2-H1-setting of the continuous formulation independent of the constitutive model. To investigate this further, various discretizations are analyzed and tested in numerical experiments. For several approximation spaces, which at first glance seem to be natural choices, further stability issues are uncovered. For some discretizations however, numerical experiments in the finite strain setting show convergence to the correct solution despite the stability issues of the continuous formulation. This gives motivation for further investigation of this circumstance in future research. Supplementary numerical results unveil the ability to avoid singularities, which would appear with classical elasticity formulations.

梯度弹性公式的优点是避免了经典弹性公式中明显的几何奇异性和相应的网格依赖有限元解。此外,通过梯度富集,模拟依赖于尺度的本构行为成为可能。为了保持C0的连续性,可以使用三场混合配方。由于到目前为止,在文献中这些只出现在小应变框架,在这个贡献公式在一般有限应变超弹性设置进行了研究。除此之外,对不稳定条件进行了调查,并揭示了相对于独立于本构模型的连续公式的l2 - h1设置缺乏稳定解的存在。为了进一步研究这一点,在数值实验中对各种离散化进行了分析和测试。对于一些近似空间,乍一看似乎是自然的选择,进一步的稳定性问题被发现。然而,对于某些离散化,在有限应变设置下的数值实验显示收敛到正确的解,尽管连续公式存在稳定性问题。这为今后进一步研究这一情况提供了动力。补充的数值结果揭示了避免奇点的能力,这在经典弹性公式中会出现。
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引用次数: 4
A diffuse modeling approach for embedded interfaces in linear elasticity 线性弹性中嵌入界面的扩散建模方法
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000001
Paul Hennig, Roland Maier, Daniel Peterseim, Dominik Schillinger, Barbara Verfürth, Markus Kästner

In this contribution, we present a diffuse modeling approach to embed material interfaces into nonconforming meshes with a focus on linear elasticity. For this purpose, a regularized indicator function is employed that describes the distribution of the different materials by a scalar value. The material in the resulting diffuse interface region is redefined in terms of this indicator function and recomputed by a homogenization of the adjacent material parameters. The applied homogenization method fulfills the kinematic compatibility across the interface and the static equilibrium at the interface. In addition, an hℓ-adaptive refinement strategy based on truncated hierarchical B-spline is applied to provide an appropriate and efficient approximation of the diffuse interface region. We justify mathematically and demonstrate numerically that the applied approach leads to optimal convergence rates in the far field for one-dimensional problems. A two-dimensional example illustrates that the application of the hℓ-adaptive refinement strategy allows for a clear reduction of the error in the near and far field and a good resolution of the local stress and strain fields at the interface. The use of a higher continuous B-spline basis leads to efficient computations due to the higher continuity of the diffuse interface model.

在这篇文章中,我们提出了一种漫射建模方法,将材料界面嵌入到非一致性网格中,重点是线性弹性。为此,采用正则化指标函数,用标量值描述不同材料的分布。由此产生的扩散界面区域中的材料根据该指示函数重新定义,并通过相邻材料参数的均匀化重新计算。所采用的均质化方法满足了跨界面的运动相容和界面处的静力平衡。此外,采用基于截断层次b样条的h - h自适应细化策略对扩散界面区域进行了适当有效的逼近。我们在数学上进行了论证,并在数值上证明了所采用的方法可以在远场得到一维问题的最优收敛速率。二维算例表明,应用h -自适应细化策略可以明显减小近场和远场误差,并能很好地分辨界面处的局部应力和应变场。由于扩散界面模型具有较高的连续性,因此使用较高的连续b样条基可以提高计算效率。
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引用次数: 8
Spline- and hp-basis functions of higher differentiability in the finite cell method 有限单元法中具有较高可微性的样条基和hp基函数
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000004
Stefan Kollmannsberger, Davide D'Angella, Ernst Rank, Wadhah Garhuom, Simeon Hubrich, Alexander Düster, Paolo Di Stolfo, Andreas Schröder

In this paper, the use of hp-basis functions with higher differentiability properties is discussed in the context of the finite cell method and numerical simulations on complex geometries. For this purpose, Ck hp-basis functions based on classical B-splines and a new approach for the construction of C1 hp-basis functions with minimal local support are introduced. Both approaches allow for hanging nodes, whereas the new C1 approach also includes varying polynomial degrees. The properties of the hp-basis functions are studied in several numerical experiments, in which a linear elastic problem with some singularities is discretized with adaptive refinements. Furthermore, the application of the Ck hp-basis functions based on B-splines is investigated in the context of nonlinear material models, namely hyperelasticity and elastoplasicity with finite strains.

本文在有限单元法和复杂几何的数值模拟的背景下,讨论了具有高可微性的hp基函数的应用。为此,提出了基于经典b样条的Ck hp-基函数和一种构造具有最小局部支持的C1 hp-基函数的新方法。两种方法都允许挂节点,而新的C1方法还包括不同的多项式度。本文通过数值实验研究了一类具有奇异性的线性弹性问题的性质,并对其进行了自适应离散化。此外,研究了基于b样条的Ck - hp基函数在非线性材料模型(即超弹性和有限应变弹塑性)中的应用。
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引用次数: 8
A detailed investigation of the model influencing parameters of the phase-field fracture approach 详细研究了相场断裂方法的影响参数模型
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000005
Carola Bilgen, Alena Kopaničáková, Rolf Krause, Kerstin Weinberg

Phase-field approaches to fracture are gaining popularity to compute a priori unknown crack paths. In this work the sensitivity of such phase-field approaches with respect to its model specific parameters, that is, the critical length of regularization, the degradation function and the mobility, is investigated. The susceptibility of the computed cracks to the setting of these parameters is studied for problems of linear and finite elasticity. Furthermore, the convergence properties of different solution strategies are analyzed. Monolithic and staggered solution schemes for the solution of the arising nonlinear discrete systems are studied in detail. To conclude, we demonstrate the versatility of the phase-field fracture approach in a real-world problem by comparing different simulations of conchoidal fracture using structured and unstructured meshes.

相场断裂分析方法在计算先验未知裂纹路径方面越来越受欢迎。在这项工作中,研究了这种相场方法相对于其模型特定参数的灵敏度,即正则化的临界长度,退化函数和迁移率。针对线弹性和有限弹性问题,研究了计算裂纹对这些参数设置的敏感性。进一步分析了不同解策略的收敛性。详细研究了非线性离散系统的整体解和交错解方案。最后,我们通过比较使用结构化和非结构化网格的不同贝壳状裂缝模拟,证明了相场压裂方法在现实问题中的通用性。
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引用次数: 6
Mesh adaptivity for quasi-static phase-field fractures based on a residual-type a posteriori error estimator 基于残差型后验误差估计的准静态相场裂缝网格自适应
Q1 Mathematics Pub Date : 2019-08-22 DOI: 10.1002/gamm.202000003
K. Mang, M. Walloth, T. Wick, W. Wollner

In this work, we consider adaptive mesh refinement for a monolithic phase-field description for fractures in brittle materials. Our approach is based on an a posteriori error estimator for the phase-field variational inequality realizing the fracture irreversibility constraint. The key goal is the development of a reliable and efficient residual-type error estimator for the phase-field fracture model in each time-step. Based on this error estimator, error indicators for local mesh adaptivity are extracted. The proposed estimator is based on a technique known for singularly perturbed equations in combination with estimators for variational inequalities. These theoretical developments are used to formulate an adaptive mesh refinement algorithm. For the numerical solution, the fracture irreversibility is imposed using a Lagrange multiplier. The resulting saddle-point system has three unknowns: displacements, phase-field, and a Lagrange multiplier for the crack irreversibility. Several numerical experiments demonstrate our theoretical findings with the newly developed estimators and the corresponding refinement strategy.

在这项工作中,我们考虑自适应网格细化的整体相场描述脆性材料的断裂。该方法基于相场变分不等式的后验误差估计,实现了断裂不可逆性约束。关键目标是为相场裂缝模型在每个时间步长中建立一个可靠、有效的残差型误差估计器。在此误差估计的基础上,提取局部网格自适应的误差指标。所提出的估计量是基于已知的奇摄动方程与变分不等式估计量相结合的技术。这些理论发展被用于制定自适应网格细化算法。对于数值解,使用拉格朗日乘子施加断裂不可逆性。由此产生的鞍点系统有三个未知数:位移、相场和裂纹不可逆性的拉格朗日乘子。一些数值实验证明了我们用新开发的估计器和相应的改进策略所得到的理论结论。
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引用次数: 23
On computational approaches of liver lobule function and perfusion simulation 肝小叶功能的计算方法及灌注模拟
Q1 Mathematics Pub Date : 2019-05-24 DOI: 10.1002/gamm.201900016
Tim Ricken, Lena Lambers

In recent years computational models have become more important for simulating hepatic processes and investigating liver diseases in silico and so various liver models have been published. The complex behavior of biological tissue with its hierarchical structure as well as the blood perfusion through the organ have been described using different approaches and numerical techniques. This paper shows and compares numerical approaches for function and perfusion simulation recently published and compares them with a multiscale function-perfusion model using the extended theory of porous media. We focus on the description of blood perfusion and liver tissue, but also on the simulation of liver diseases or the zonation of processes in the liver. Furthermore, the selected geometry is taken into account.

近年来,计算模型在模拟肝脏过程和研究肝脏疾病方面变得越来越重要,因此各种肝脏模型已经发表。生物组织的复杂行为及其层次结构以及血液在器官中的灌注已经用不同的方法和数值技术进行了描述。本文展示和比较了最近发表的功能和灌注模拟的数值方法,并将它们与基于多孔介质扩展理论的多尺度功能灌注模型进行了比较。我们专注于血液灌注和肝脏组织的描述,但也对肝脏疾病的模拟或肝脏过程的分区。此外,还考虑了所选择的几何形状。
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引用次数: 5
A study of growth and remodeling in isotropic tissues, based on the Anand-Aslan-Chester theory of strain-gradient plasticity 基于应变梯度塑性的Anand-Aslan-Chester理论的各向同性组织生长和重塑研究
Q1 Mathematics Pub Date : 2019-05-22 DOI: 10.1002/gamm.201900015
Alfio Grillo, Salvatore Di Stefano, Ariel Ramírez-Torres, Michele Loverre

Motivated by the increasing interest of the biomechanical community towards the employment of strain-gradient theories for solving biological problems, we study the growth and remodeling of a biological tissue on the basis of a strain-gradient formulation of remodeling. Our scope is to evaluate the impact of such an approach on the principal physical quantities that determine the growth of the tissue. For our purposes, we assume that remodeling is characterized by a coarse and a fine length scale and, taking inspiration from a work by Anand, Aslan, and Chester, we introduce a kinematic variable that resolves the fine scale inhomogeneities induced by remodeling. With respect to this variable, a strain-gradient framework of remodeling is developed. We adopt this formulation in order to investigate how a tumor tissue grows and how it remodels in response to growth. In particular, we focus on a type of remodeling that manifests itself in two different, but complementary, ways: on the one hand, it finds its expression in a stress-induced reorganization of the adhesion bonds among the tumor cells, and, on the other hand, it leads to a change of shape of the cells and of the tissue, which is generally not recovered when external loads are removed. To address this situation, we resort to a generalized Bilby-Kröner-Lee decomposition of the deformation gradient tensor. We test our model on a benchmark problem taken from the literature, which we rephrase in two ways: microscale remodeling is disregarded in the first case, and accounted for in the second one. Finally, we compare and discuss the obtained numerical results.

由于生物力学界对利用应变梯度理论解决生物问题的兴趣日益浓厚,我们在应变梯度重塑公式的基础上研究了生物组织的生长和重塑。我们的范围是评估这种方法对决定组织生长的主要物理量的影响。出于我们的目的,我们假设重塑的特征是粗和细长度尺度,并从Anand, Aslan和Chester的作品中获得灵感,我们引入了一个运动学变量来解决重塑引起的细尺度不均匀性。在此基础上,建立了应变梯度重构框架。我们采用这个公式是为了研究肿瘤组织是如何生长的,以及它是如何随着生长而重塑的。我们特别关注一种以两种不同但互补的方式表现出来的重塑:一方面,它在肿瘤细胞之间的粘附键的应力诱导重组中表现出来,另一方面,它导致细胞和组织形状的变化,这种变化通常在去除外部负载后不会恢复。为了解决这种情况,我们求助于变形梯度张量的广义Bilby-Kröner-Lee分解。我们在取自文献的基准问题上测试我们的模型,我们以两种方式重新表述:在第一种情况下忽略微尺度重塑,并在第二种情况下考虑。最后,对得到的数值结果进行了比较和讨论。
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引用次数: 12
The dynamics of the skeletal muscle: A systems biophysics perspective on muscle modeling with the focus on Hill-type muscle models 骨骼肌动力学:肌肉建模的系统生物物理学观点,重点是希尔型肌肉模型
Q1 Mathematics Pub Date : 2019-05-21 DOI: 10.1002/gamm.201900013
Syn Schmitt, Michael Günther, Daniel F. B. Häufle

Skeletal muscle is one of the most fascinating and crucial ingredients of motion generation in nature. Since the beginning of science, people dedicate their life as researchers to enhance knowledge about this biological motor. Thus, the scientific knowledge about the skeletal muscle is overwhelmingly broad and detailed. This contribution collects knowledge about the active and passive dynamics of skeletal muscle. Furthermore, it highlights a special perspective in which not only the muscle itself, but also the role muscles play in the interaction with other structures is studied. The first section introduces this systems biophysics perspective, which clusters the investigation of the relations, interactions and dependencies between muscles and the other structures in the movement apparatus. In the second section, the muscles are considered in more detail by describing three approaches to muscle modeling. The third section deals with recent advances based on Hill-type models, such as, for example, the integration of mass.

骨骼肌是自然界中产生运动的最迷人和最重要的成分之一。自从有了科学,人们就把自己的一生奉献给了研究人员,以提高对这种生物运动的认识。因此,关于骨骼肌的科学知识极其广泛和详细。这一贡献收集了有关骨骼肌主动和被动动力学的知识。此外,它还突出了一个特殊的视角,不仅研究了肌肉本身,还研究了肌肉在与其他结构相互作用中的作用。第一部分介绍了这个系统生物物理学的观点,它聚集了肌肉和运动器械中其他结构之间的关系、相互作用和依赖关系的调查。在第二节中,通过描述肌肉建模的三种方法,更详细地考虑了肌肉。第三部分讨论了基于hill型模型的最新进展,例如质量的集成。
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引用次数: 12
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GAMM Mitteilungen
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