J. C. Reséndiz-Aparicio, J. Pérez-García, Efraín Olivas-Peña, Enrique García-Cuevas, Yuridia L. Roque-Villavicencio, Marisela Hernández-Hernández, J. I. Castro-Macías, J. D. Rayo-Mares
The current definition of epilepsy proposes three possibilities in which to consider this diagnosis, the first when a patient has two or more unprovoked or reflex seizures separated in 24 h, the second, an unprovoked or reflected seizure with a proba-bility of continuing to present seizures of at least 60%, and the third, the presence of an epileptic syndrome. The classification of the type of seizure divides them into three possibilities depending on how they begin: those of focal, generalized and unknown initiation. Focal seizures can be subclassified in those that have loss or not consciousness, and then categorized depending on whether the symptoms are motor or non-motor, and give a descriptor of the event, which is nothing else but the description of symptoms and signs that presents the patient in the seizure. The classification of the type of epilepsy proposes three diagnostic levels: the first related to the type of seizure, the second to the type of epilepsy and the third to the type of epileptic syndrome, without forgetting the etiology and comorbidity. These concepts are basic in the approach of any patient who presents epilepsy.
{"title":"Guía clínica. Definición y clasificación de la epilepsia","authors":"J. C. Reséndiz-Aparicio, J. Pérez-García, Efraín Olivas-Peña, Enrique García-Cuevas, Yuridia L. Roque-Villavicencio, Marisela Hernández-Hernández, J. I. Castro-Macías, J. D. Rayo-Mares","doi":"10.24875/rmn.m19000052","DOIUrl":"https://doi.org/10.24875/rmn.m19000052","url":null,"abstract":"The current definition of epilepsy proposes three possibilities in which to consider this diagnosis, the first when a patient has two or more unprovoked or reflex seizures separated in 24 h, the second, an unprovoked or reflected seizure with a proba-bility of continuing to present seizures of at least 60%, and the third, the presence of an epileptic syndrome. The classification of the type of seizure divides them into three possibilities depending on how they begin: those of focal, generalized and unknown initiation. Focal seizures can be subclassified in those that have loss or not consciousness, and then categorized depending on whether the symptoms are motor or non-motor, and give a descriptor of the event, which is nothing else but the description of symptoms and signs that presents the patient in the seizure. The classification of the type of epilepsy proposes three diagnostic levels: the first related to the type of seizure, the second to the type of epilepsy and the third to the type of epileptic syndrome, without forgetting the etiology and comorbidity. These concepts are basic in the approach of any patient who presents epilepsy.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45392516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. O. González-Vargas, Yamil Matuk-Pérez, José L. Sosa Hernández, Gerardo Quiñones-Canales, Sandra E. Silva-Sánchez, Gerónimo Aguayo-Leytte, Sergio Medina-Benitez, J. Ibarra-Puig, María del C. Loy-Gerala, E. Castro-Martínez
Women of childbearing age and pregnant women have physiological modifications that make think in a particular way about epilepsy and the management of antiepileptic drugs in them. These guidelines address both the effects of epilepsy in the gynecological and the obstetric aspects of the woman, with a series of recommendations based on evidence-based medicine.
{"title":"Guía clínica. Epilepsia en la mujer embarazada y en edad fértil","authors":"P. O. González-Vargas, Yamil Matuk-Pérez, José L. Sosa Hernández, Gerardo Quiñones-Canales, Sandra E. Silva-Sánchez, Gerónimo Aguayo-Leytte, Sergio Medina-Benitez, J. Ibarra-Puig, María del C. Loy-Gerala, E. Castro-Martínez","doi":"10.24875/rmn.m19000048","DOIUrl":"https://doi.org/10.24875/rmn.m19000048","url":null,"abstract":"Women of childbearing age and pregnant women have physiological modifications that make think in a particular way about epilepsy and the management of antiepileptic drugs in them. These guidelines address both the effects of epilepsy in the gynecological and the obstetric aspects of the woman, with a series of recommendations based on evidence-based medicine.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42152206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Correspondencia: *Juan Carlos Reséndiz-Aparicio E-mail: jc_doc@yahoo.com Disponible en internet: 09-08-2019 Rev Mex Neuroci. 2019;20(2):1-6 www.revmexneurociencia.com Fecha de recepción: 01-02-2019 Fecha de aceptación: 28-02-2019 DOI: 10.24875/RMN.M19000051 El Programa Prioritario de Epilepsia (PPE) del sector salud fue creado con base en el acuerdo publicado en el Diario Oficial de la Federación del 24 de octubre de 1984. Este programa ha trabajado de manera ininterrumpida para normar, coordinar, sistematizar y optimizar las estrategias a favor del paciente que padece epilepsia, sus familias y la sociedad. Actualmente cuenta con 78 centros de atención integral para la epilepsia en todo el país, ubicados en instituciones hospitalarias de todo el sector salud. La sede de la coordinación nacional se encuentra en el Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suarez, Instituto Nacional de Neurología y Neurocirugía (INNN), en la Ciudad de México, desde donde se planean las acciones necesarias para esta labor. La coordinación nacional, desde la oficina del Instituto, está a cargo de su creador y fundador, el Dr. Francisco Rubio Donnadieu, y de un servidor. La realización de estas primeras Guías Clínicas (GC) ha sido un trabajo laborioso, pero que se ha podido concluir gracias al trabajo de todos los coordinadores del PPE, quienes son neurólogos y neurólogos pediatras certificados por el Consejo Mexicano de Neurología y trabajan en alguna institución del sector salud en nuestro país. Para la elaboración tuvimos dos reuniones presenciales, la primera en la ciudad de León y la segunda en la ciudad de Puebla, creando mesas de trabajo, una para cada GC, reuniones que logramos gracias al apoyo del gobierno federal y de aportaciones de laboratorios farmacéuticos que ayudan cada año en la capacitación de los médicos de primer contacto. Estas GC están diseñadas para ayudar al médico de primer contacto y al especialista a tomar decisiones adecuadas en el abordaje de pacientes que padecen epilepsia en diferentes grupos de
{"title":"Guías clínicas del Programa Prioritario de Epilepsia del Sector Salud, México","authors":"J. C. Reséndiz-Aparicio","doi":"10.24875/rmn.m19000051","DOIUrl":"https://doi.org/10.24875/rmn.m19000051","url":null,"abstract":"Correspondencia: *Juan Carlos Reséndiz-Aparicio E-mail: jc_doc@yahoo.com Disponible en internet: 09-08-2019 Rev Mex Neuroci. 2019;20(2):1-6 www.revmexneurociencia.com Fecha de recepción: 01-02-2019 Fecha de aceptación: 28-02-2019 DOI: 10.24875/RMN.M19000051 El Programa Prioritario de Epilepsia (PPE) del sector salud fue creado con base en el acuerdo publicado en el Diario Oficial de la Federación del 24 de octubre de 1984. Este programa ha trabajado de manera ininterrumpida para normar, coordinar, sistematizar y optimizar las estrategias a favor del paciente que padece epilepsia, sus familias y la sociedad. Actualmente cuenta con 78 centros de atención integral para la epilepsia en todo el país, ubicados en instituciones hospitalarias de todo el sector salud. La sede de la coordinación nacional se encuentra en el Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suarez, Instituto Nacional de Neurología y Neurocirugía (INNN), en la Ciudad de México, desde donde se planean las acciones necesarias para esta labor. La coordinación nacional, desde la oficina del Instituto, está a cargo de su creador y fundador, el Dr. Francisco Rubio Donnadieu, y de un servidor. La realización de estas primeras Guías Clínicas (GC) ha sido un trabajo laborioso, pero que se ha podido concluir gracias al trabajo de todos los coordinadores del PPE, quienes son neurólogos y neurólogos pediatras certificados por el Consejo Mexicano de Neurología y trabajan en alguna institución del sector salud en nuestro país. Para la elaboración tuvimos dos reuniones presenciales, la primera en la ciudad de León y la segunda en la ciudad de Puebla, creando mesas de trabajo, una para cada GC, reuniones que logramos gracias al apoyo del gobierno federal y de aportaciones de laboratorios farmacéuticos que ayudan cada año en la capacitación de los médicos de primer contacto. Estas GC están diseñadas para ayudar al médico de primer contacto y al especialista a tomar decisiones adecuadas en el abordaje de pacientes que padecen epilepsia en diferentes grupos de","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42438924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Visoso-Franco, L. Romero-Ocampo, J. Santos-Zambrano, A. Serrano-González, E. Castro-Martínez
mediante la correcta anamnesis, exploración física y los estudios precisos de laboratorio las y evitando así Palabras clave: epilépticas. Epilepsia. Tratamiento en servicio de urgencias. Abstract This clinical guideline on epilepsy contains levels of evidence and recommendations based on the scientific method. Its primary function is to provide emergency medicine physicians a clear diagnostic approach when they faced a pediatric or adult patient with epileptic seizures (ES) or epilepsy. The objective is to unify criteria; this will ensure integral health care, based on adequate decision-making, benefiting the patient through the individualized analysis of a correct anamnesis, phy-sical examination, precise indication of laboratory, and image diagnostic tests that will allow the pertinent clinical and pharmacological treatment for opportune interventions, avoiding complications, and whenever possible, the recurrence of the ES.
{"title":"Guía clínica. Manejo de crisis epilépticas en el Servicio de Urgencias","authors":"José Visoso-Franco, L. Romero-Ocampo, J. Santos-Zambrano, A. Serrano-González, E. Castro-Martínez","doi":"10.24875/rmn.m19000053","DOIUrl":"https://doi.org/10.24875/rmn.m19000053","url":null,"abstract":"mediante la correcta anamnesis, exploración física y los estudios precisos de laboratorio las y evitando así Palabras clave: epilépticas. Epilepsia. Tratamiento en servicio de urgencias. Abstract This clinical guideline on epilepsy contains levels of evidence and recommendations based on the scientific method. Its primary function is to provide emergency medicine physicians a clear diagnostic approach when they faced a pediatric or adult patient with epileptic seizures (ES) or epilepsy. The objective is to unify criteria; this will ensure integral health care, based on adequate decision-making, benefiting the patient through the individualized analysis of a correct anamnesis, phy-sical examination, precise indication of laboratory, and image diagnostic tests that will allow the pertinent clinical and pharmacological treatment for opportune interventions, avoiding complications, and whenever possible, the recurrence of the ES.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47115520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. C. Reséndiz-Aparicio, Jesús M. Padilla-Huicab, I. Martínez-Juárez, Gustavo Hernández-Martínez, Eunice López-Correa, Benjamín Vázquez-Juárez, Rosana Huerta-Albarrán, Claudia Rivera-Acuña
Approximately 65% of children with newly diagnosed epilepsy achieve sustained control of their epileptic seizures with the antiepileptic drug (AED) initially prescribed, and 15-20% require the combination of other AEDs. To begin treatment with an AED, basic aspects should be considered, such as the capacity for absorption, distribution, metabolism, and elimination of the drug. Treatment with an AED in pediatric patients, as for any age, must be personalized, but in these cases, the biological age and its degree of development are fundamental. Furthermore, the type of seizure, type of epileptic syndrome, comorbidity,
{"title":"Guía clínica. Fármacos antiepilépticos de elección para síndromes epilépticos y epilepsias en pacientes en edad pediátrica","authors":"J. C. Reséndiz-Aparicio, Jesús M. Padilla-Huicab, I. Martínez-Juárez, Gustavo Hernández-Martínez, Eunice López-Correa, Benjamín Vázquez-Juárez, Rosana Huerta-Albarrán, Claudia Rivera-Acuña","doi":"10.24875/rmn.m19000056","DOIUrl":"https://doi.org/10.24875/rmn.m19000056","url":null,"abstract":"Approximately 65% of children with newly diagnosed epilepsy achieve sustained control of their epileptic seizures with the antiepileptic drug (AED) initially prescribed, and 15-20% require the combination of other AEDs. To begin treatment with an AED, basic aspects should be considered, such as the capacity for absorption, distribution, metabolism, and elimination of the drug. Treatment with an AED in pediatric patients, as for any age, must be personalized, but in these cases, the biological age and its degree of development are fundamental. Furthermore, the type of seizure, type of epileptic syndrome, comorbidity,","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47584093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José A. Gien-López, Raymundo A. Cuevas-Escalante, Enrique García-Cuevas, María del R. Márquez-Estudillo, Blanca E. Villaseñor-Anguiano, Raúl Leal-Cantú, R. E. Jiménez-Arredondo
Unprovoked seizures represent a challenge in the neurology office consult. Proper identification of the first unprovoked seizure must be the first step of the adequate treatment and for this there are different diagnostic tools that help in the establi-shment of percentage risk of a second seizure or the presence of epilepsy, as well as recurrence factors for a first time unprovoked seizure. Likewise, indication for pharmacological treatment for the first unprovoked seizure is described and we move forward to the reference to the next level of medical attention. One important component of the management after the first unprovoked crisis are the nonmedical recommendations to the patient and family after the first unprovoked seizure. This Mexican Guideline was elaborated accounting the resources available of our hospitals and the diagnostic tools in both public and private hospitals.
{"title":"Guía clínica. Manejo de la primera crisis epiléptica no provocada en adultos y niños","authors":"José A. Gien-López, Raymundo A. Cuevas-Escalante, Enrique García-Cuevas, María del R. Márquez-Estudillo, Blanca E. Villaseñor-Anguiano, Raúl Leal-Cantú, R. E. Jiménez-Arredondo","doi":"10.24875/rmn.m19000054","DOIUrl":"https://doi.org/10.24875/rmn.m19000054","url":null,"abstract":"Unprovoked seizures represent a challenge in the neurology office consult. Proper identification of the first unprovoked seizure must be the first step of the adequate treatment and for this there are different diagnostic tools that help in the establi-shment of percentage risk of a second seizure or the presence of epilepsy, as well as recurrence factors for a first time unprovoked seizure. Likewise, indication for pharmacological treatment for the first unprovoked seizure is described and we move forward to the reference to the next level of medical attention. One important component of the management after the first unprovoked crisis are the nonmedical recommendations to the patient and family after the first unprovoked seizure. This Mexican Guideline was elaborated accounting the resources available of our hospitals and the diagnostic tools in both public and private hospitals.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42154446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María del C. Loy-Gerala, Octavio M. Ibarra-Bravo, María del R. Márquez-Estudillo, F. Mena-Barranco, Francisco J. Rogel-Ortiz, Sandra E. Silva-Sánchez, Hilda Villegas-Peña, Avril Molina-García
{"title":"Guía clínica. Suspensión del tratamiento crónico con antiepilépticos","authors":"María del C. Loy-Gerala, Octavio M. Ibarra-Bravo, María del R. Márquez-Estudillo, F. Mena-Barranco, Francisco J. Rogel-Ortiz, Sandra E. Silva-Sánchez, Hilda Villegas-Peña, Avril Molina-García","doi":"10.24875/rmn.m19000058","DOIUrl":"https://doi.org/10.24875/rmn.m19000058","url":null,"abstract":"","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42473642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ruíz-García, Mario A. Alonso-Vanegas, S. P. Pérez-Reyes, Gerardo Quiñones-Canales, Ildefonso Rodríguez-Leyva, H. R. Martínez-Rodríguez, E. Barragán-Pérez
Epilepsy surgery is an approved treatment for the management of drug-resistant epilepsy. Approximately one third of patients with epilepsy present refractory epilepsy (RE). RE is considered a grave public health threat, carrying important bio-psy-cho-social consequences including accidents, professional limitations and increased risk of sudden death. Surgery is asso-ciated with seizure freedom in approximately 65% of patients after five years of follow-up. Patients with drug-resistant epilepsy should be referred to a specialized center for presurgical evaluation. Presurgical evaluation requires minimally detailed clinical analysis, electroencephalogram, video-electroencephalogram, magnetic resonance imaging, neuropsychological and developmental evaluation, and psychiatric evaluation. The most frequent surgical procedures are temporal lobe resections, followed by extratemporal and multilobar resections, lesionectomy, hemispherectomies, callosotomies and multiple subpial transections.
{"title":"Guía clínica. Evaluación prequirúrgica en epilepsia refractaria","authors":"M. Ruíz-García, Mario A. Alonso-Vanegas, S. P. Pérez-Reyes, Gerardo Quiñones-Canales, Ildefonso Rodríguez-Leyva, H. R. Martínez-Rodríguez, E. Barragán-Pérez","doi":"10.24875/rmn.m22000088","DOIUrl":"https://doi.org/10.24875/rmn.m22000088","url":null,"abstract":"Epilepsy surgery is an approved treatment for the management of drug-resistant epilepsy. Approximately one third of patients with epilepsy present refractory epilepsy (RE). RE is considered a grave public health threat, carrying important bio-psy-cho-social consequences including accidents, professional limitations and increased risk of sudden death. Surgery is asso-ciated with seizure freedom in approximately 65% of patients after five years of follow-up. Patients with drug-resistant epilepsy should be referred to a specialized center for presurgical evaluation. Presurgical evaluation requires minimally detailed clinical analysis, electroencephalogram, video-electroencephalogram, magnetic resonance imaging, neuropsychological and developmental evaluation, and psychiatric evaluation. The most frequent surgical procedures are temporal lobe resections, followed by extratemporal and multilobar resections, lesionectomy, hemispherectomies, callosotomies and multiple subpial transections.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47078663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro Olmos-López, Jorge Ibarra-Aguilar, JO Cornelio-Nieto, L. A. Ocaña-Hernández, Mario A. Márquez-Amaya, N. A. Luna-López, J. C. Reséndiz-Aparicio, Ildefonso Rodríguez-Leyva
A generalized epileptic seizure lasting five or more minutes, or the presence of two or more seizures without recovery of consciousness in thirty minutes, or a focal seizure that persists for more than 10 min or with altered consciousness for 60 min or more duration is called status epilepticus. It can be classified into generalized and focal, motor and non-motor. Its etiology may or may not be recognized. The electroencephalographic pattern shows focal or generalized persistent epileptic activity. It is a dangerous situation, which requires algorithmic management since it is detected, in the emergency Room and if required in the intensive therapy unit. In-hospital management would include the initial ABCDE , hypertonic glucose solution and thiamin if hypoglycemia is detected. Lorazepam (midazolam or diazepam) to juggle seizures, followed by phenytoin, valproate or levetiracetam in impregnation and sustain. If the status epilepticus persists for more than an hour, the patient will be referred to an ICU
{"title":"Guía clínica. Estado epiléptico en niños y adultos","authors":"Alejandro Olmos-López, Jorge Ibarra-Aguilar, JO Cornelio-Nieto, L. A. Ocaña-Hernández, Mario A. Márquez-Amaya, N. A. Luna-López, J. C. Reséndiz-Aparicio, Ildefonso Rodríguez-Leyva","doi":"10.24875/rmn.m19000049","DOIUrl":"https://doi.org/10.24875/rmn.m19000049","url":null,"abstract":"A generalized epileptic seizure lasting five or more minutes, or the presence of two or more seizures without recovery of consciousness in thirty minutes, or a focal seizure that persists for more than 10 min or with altered consciousness for 60 min or more duration is called status epilepticus. It can be classified into generalized and focal, motor and non-motor. Its etiology may or may not be recognized. The electroencephalographic pattern shows focal or generalized persistent epileptic activity. It is a dangerous situation, which requires algorithmic management since it is detected, in the emergency Room and if required in the intensive therapy unit. In-hospital management would include the initial ABCDE , hypertonic glucose solution and thiamin if hypoglycemia is detected. Lorazepam (midazolam or diazepam) to juggle seizures, followed by phenytoin, valproate or levetiracetam in impregnation and sustain. If the status epilepticus persists for more than an hour, the patient will be referred to an ICU","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42044700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Anaya-Escamilla, Luis E. Martínez‐Bravo, Gilberto A. Jiménez-Castillo
Cognitive impairment is a potential short- and long-term disease consequence of COVID-19 virus, the exact mechanism is still in debate. One of their potential linking is with diabetes. Diabetes and COVID-19 infection have possible multiple common mechanisms that could ensue cognitive impairment as pulmonary microthrombi (silent hypoxia);endothelial dysfunction;cerebral vascular injury oxidative stress;renin-angiotensin-aldosterone system;and galectine and interferon responses. In addition, histological markers as amyloid AB plaques and neurofibrillary tangle of Tau protein are common in both pathologies. Despite of this evidence, diabetes mellitus and COVID-19 in cognitive impairment are establishing a bright light in terms of neurological progress. This article describes the relationship between diabetes mellitus and COVID-19 as potential cause of cognitive impairment. (English) [ FROM AUTHOR]
{"title":"COVID-19 and diabetes mellitus in cognitive impairment: an undrawn relationship","authors":"Antonio Anaya-Escamilla, Luis E. Martínez‐Bravo, Gilberto A. Jiménez-Castillo","doi":"10.24875/rmn.22000039","DOIUrl":"https://doi.org/10.24875/rmn.22000039","url":null,"abstract":"Cognitive impairment is a potential short- and long-term disease consequence of COVID-19 virus, the exact mechanism is still in debate. One of their potential linking is with diabetes. Diabetes and COVID-19 infection have possible multiple common mechanisms that could ensue cognitive impairment as pulmonary microthrombi (silent hypoxia);endothelial dysfunction;cerebral vascular injury oxidative stress;renin-angiotensin-aldosterone system;and galectine and interferon responses. In addition, histological markers as amyloid AB plaques and neurofibrillary tangle of Tau protein are common in both pathologies. Despite of this evidence, diabetes mellitus and COVID-19 in cognitive impairment are establishing a bright light in terms of neurological progress. This article describes the relationship between diabetes mellitus and COVID-19 as potential cause of cognitive impairment. (English) [ FROM AUTHOR]","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48933976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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