Paola Núñez-Contreras, Daniela Granado-Rocha, Maritza Carvajal-Game, Ana M. Torres-Perez
{"title":"Aspects of neurodevelopment between autism spectrum disorders and epilepsy","authors":"Paola Núñez-Contreras, Daniela Granado-Rocha, Maritza Carvajal-Game, Ana M. Torres-Perez","doi":"10.24875/rmn.20000055","DOIUrl":"https://doi.org/10.24875/rmn.20000055","url":null,"abstract":"","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44424980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catalina Márquez-Martín, R. J. García-Bermúdez, B. Bertado-Cortés
Objective: Describing the occurrence of infections in patients with relapsing-remitting multiple sclerosis (RRMS) treated with fingolimod and with different degrees of lymphopenia in our unit. Patients and Methods: Observational, descriptive, longitudinal, and retrospective study in the Hospital Centro Médico Nacional Siglo XXI. Patients with RRMS and treatment with fingolimod were grouped based on lymphocyte count and infections. Quantitative variables were expressed as mean, standard deviation, and interquartile range;qualitative variables were expressed as frequencies and percentages. Results: 110 patients, 76 (69.1%) female, 34 (30.9%) male, mean age 38.3 years (17-63, SD 9.85). Mean of initial expanded disability status scale 1.59 (0-5.5, SD 1.15) with a mean diagnosis time of 63.6 months (3-252, SD 50.96). Prior to starting fingolimod, 90.09% of patients had lymphocyte count >1,000. At six months of treatment, 35.64% had lymphocyte >1,000. At twelve months 32.95% had lymphocyte from 501 to 700. At 24 months, 34.21% had lymphocyte from 701 to 1,000. Of the 110 patients, 31.8% had mild infections, of which pharyngitis was reported in 10%, gastroenteritis 2.7%, urinary tract infection 10.9%, HPV infection 0.9%, SARS-CoV-2 infection 3.6%, ophthalmic herpes 0.9%, molluscum contagiosum 0.9%, oral candidiasis 0.9%. 68.18% did not present infections of any kind, no serious infections were reported even with lymphocyte levels below 200. Conclusions: Selective lymphopenia caused by fingolimod was not associated with infections of any kind in this population even at levels of 200-500 cells/mm³. (English) [ FROM AUTHOR] Objetivo: Describir la ocurrencia de infecciones severas en pacientes con EMRR tratados con fingolimod y con diferentes grados de linfopenia en nuestra unidad Métodos: Estudio observacional, descriptivo, longitudinal y retrospectivo realizado en el Hospital Centro Médico Nacional Siglo XXI. Pacientes con EMRR tratados con fingolimod, se agruparon por grados de linfopenia e infecciones. Las variables cuantitativas se expresaron como media, desviación estándar y rango intercuartil;las variables cualitativas se expresaron en frecuencias y porcentajes. Resultados: 110 pacientes, 76 mujeres (69.1%), 34 hombres (30.9%), media de edad 38.39 (17-63 DE 9.85). Media EDSS inicial 1.59 (0-5.5, DE 1.15), tiempo diagnóstico medio 63.67 meses (3-252, DE 50.96). Previo al inicio de fingolimod, 90.09% de los pacientes tenía linfocitos absolutos >1,000. A los 6 meses de tratamiento, 35.64% tenía >1,000 linfocitos. A los 12 meses el 32.95% tenía 501-700 linfocitos, a los 24 meses el 34.21% tenía 701-1,000 linfocitos. De los 110 pacientes, el 31.8% presentó infecciones leves, de las cuales se informó faringitis en 10%, gastroenteritis 2.7%, infección del tracto urinario 10.9%, infección por VPH 0.9%, infección por SARS-CoV-2 3.6%, herpes oftálmico 0.9%, molusco contagioso 0.9%, candidiasis oral 0.9%. El 68.18% no presentó infecciones de ningún tipo, no se
{"title":"Are different degrees of lymphopenia for FTY720 associated with serious infectious-type events? No","authors":"Catalina Márquez-Martín, R. J. García-Bermúdez, B. Bertado-Cortés","doi":"10.24875/rmn.21000048","DOIUrl":"https://doi.org/10.24875/rmn.21000048","url":null,"abstract":"Objective: Describing the occurrence of infections in patients with relapsing-remitting multiple sclerosis (RRMS) treated with fingolimod and with different degrees of lymphopenia in our unit. Patients and Methods: Observational, descriptive, longitudinal, and retrospective study in the Hospital Centro Médico Nacional Siglo XXI. Patients with RRMS and treatment with fingolimod were grouped based on lymphocyte count and infections. Quantitative variables were expressed as mean, standard deviation, and interquartile range;qualitative variables were expressed as frequencies and percentages. Results: 110 patients, 76 (69.1%) female, 34 (30.9%) male, mean age 38.3 years (17-63, SD 9.85). Mean of initial expanded disability status scale 1.59 (0-5.5, SD 1.15) with a mean diagnosis time of 63.6 months (3-252, SD 50.96). Prior to starting fingolimod, 90.09% of patients had lymphocyte count >1,000. At six months of treatment, 35.64% had lymphocyte >1,000. At twelve months 32.95% had lymphocyte from 501 to 700. At 24 months, 34.21% had lymphocyte from 701 to 1,000. Of the 110 patients, 31.8% had mild infections, of which pharyngitis was reported in 10%, gastroenteritis 2.7%, urinary tract infection 10.9%, HPV infection 0.9%, SARS-CoV-2 infection 3.6%, ophthalmic herpes 0.9%, molluscum contagiosum 0.9%, oral candidiasis 0.9%. 68.18% did not present infections of any kind, no serious infections were reported even with lymphocyte levels below 200. Conclusions: Selective lymphopenia caused by fingolimod was not associated with infections of any kind in this population even at levels of 200-500 cells/mm³. (English) [ FROM AUTHOR] Objetivo: Describir la ocurrencia de infecciones severas en pacientes con EMRR tratados con fingolimod y con diferentes grados de linfopenia en nuestra unidad Métodos: Estudio observacional, descriptivo, longitudinal y retrospectivo realizado en el Hospital Centro Médico Nacional Siglo XXI. Pacientes con EMRR tratados con fingolimod, se agruparon por grados de linfopenia e infecciones. Las variables cuantitativas se expresaron como media, desviación estándar y rango intercuartil;las variables cualitativas se expresaron en frecuencias y porcentajes. Resultados: 110 pacientes, 76 mujeres (69.1%), 34 hombres (30.9%), media de edad 38.39 (17-63 DE 9.85). Media EDSS inicial 1.59 (0-5.5, DE 1.15), tiempo diagnóstico medio 63.67 meses (3-252, DE 50.96). Previo al inicio de fingolimod, 90.09% de los pacientes tenía linfocitos absolutos >1,000. A los 6 meses de tratamiento, 35.64% tenía >1,000 linfocitos. A los 12 meses el 32.95% tenía 501-700 linfocitos, a los 24 meses el 34.21% tenía 701-1,000 linfocitos. De los 110 pacientes, el 31.8% presentó infecciones leves, de las cuales se informó faringitis en 10%, gastroenteritis 2.7%, infección del tracto urinario 10.9%, infección por VPH 0.9%, infección por SARS-CoV-2 3.6%, herpes oftálmico 0.9%, molusco contagioso 0.9%, candidiasis oral 0.9%. El 68.18% no presentó infecciones de ningún tipo, no se ","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48768743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Correspondence: *Ildefonso Rodríguez-Leyva E-mail: ilrole@yahoo.com.mx Available online: 02-05-2022 Rev Mex Neuroci. 2022;23(3):79 www.revmexneurociencia.com Date of reception: 04-03-2022 Date of acceptance: 04-03-2022 DOI: 10.24875/RMN.M22000086 The difficult situation that humanity faces when one part of it confronts another could be compared to a social disease. Without having yet emerged from a pandemic, we are now facing another conflict that will have an impact on mortality and the global economy. War is a social conflict that goes with the same history of humanity and it is usually experienced not only between nations but also within each country, each small society, and even within families. Neurologists often find it necessary to certify that the patriarch or the mother of a family is unable to make decisions due to a fixed or progressive cognitive deterioration, while the children break their ties out of economic ambition or simply for the sake of power. The same happens in social groups, organizations, and societies. The quest to have more, the envy, the desire to transcend or to feel powerful makes people’s and nations’ leaders to be both admired and hated at the same time. The followers will applaud the aggressions, while the opponents will mark distance and will try to convince others about the unfairness of the warlike maneuver that the leader is exercising. The same happens with organizations: the representative tends to forget those who supported him and exercises their power by rewarding those close to them, their friends, and cornering those who dare to raise their voices demanding justice or at least space. Are these social struggles a reflection of the illness of a leader who tries to exercise his will? The answer is not simple, justice has its edges and what is valid in one society may be punished in another, what is logical and adequate for one group may be crushing and impoverishing for another. What I believe is always terrible, no matter which perspective it belongs to, is the loss of lives that were not even participating or had minimal interest in the conflict generated, as well as the fact that people have to leave their homes, their homeland, and their family, for the interest of others. It is unfortunate to have to leave a whole history, belongings, and memories behind or to have them destroyed by someone who feels superior because they carry a weapon. In what area of our brain does the war process initiate? There is no doubt that this is the organ that creates good and bad actions, the one generates envy, ambition, destruction, and war. Countries like ours are living their own war, as incredible as it may seem, as many people die because of social conflicts as the lives that are being lost in Ukraine and the most unfortunate thing seems to be the indifference in which many of us seem to carry the situation, “as long as, it does not affect me, my family, my friends, and my interests, it does not matter.” However, ev
{"title":"We are at war","authors":"Ildefonso Rodríguez-Leyva","doi":"10.24875/rmn.m22000086","DOIUrl":"https://doi.org/10.24875/rmn.m22000086","url":null,"abstract":"Correspondence: *Ildefonso Rodríguez-Leyva E-mail: ilrole@yahoo.com.mx Available online: 02-05-2022 Rev Mex Neuroci. 2022;23(3):79 www.revmexneurociencia.com Date of reception: 04-03-2022 Date of acceptance: 04-03-2022 DOI: 10.24875/RMN.M22000086 The difficult situation that humanity faces when one part of it confronts another could be compared to a social disease. Without having yet emerged from a pandemic, we are now facing another conflict that will have an impact on mortality and the global economy. War is a social conflict that goes with the same history of humanity and it is usually experienced not only between nations but also within each country, each small society, and even within families. Neurologists often find it necessary to certify that the patriarch or the mother of a family is unable to make decisions due to a fixed or progressive cognitive deterioration, while the children break their ties out of economic ambition or simply for the sake of power. The same happens in social groups, organizations, and societies. The quest to have more, the envy, the desire to transcend or to feel powerful makes people’s and nations’ leaders to be both admired and hated at the same time. The followers will applaud the aggressions, while the opponents will mark distance and will try to convince others about the unfairness of the warlike maneuver that the leader is exercising. The same happens with organizations: the representative tends to forget those who supported him and exercises their power by rewarding those close to them, their friends, and cornering those who dare to raise their voices demanding justice or at least space. Are these social struggles a reflection of the illness of a leader who tries to exercise his will? The answer is not simple, justice has its edges and what is valid in one society may be punished in another, what is logical and adequate for one group may be crushing and impoverishing for another. What I believe is always terrible, no matter which perspective it belongs to, is the loss of lives that were not even participating or had minimal interest in the conflict generated, as well as the fact that people have to leave their homes, their homeland, and their family, for the interest of others. It is unfortunate to have to leave a whole history, belongings, and memories behind or to have them destroyed by someone who feels superior because they carry a weapon. In what area of our brain does the war process initiate? There is no doubt that this is the organ that creates good and bad actions, the one generates envy, ambition, destruction, and war. Countries like ours are living their own war, as incredible as it may seem, as many people die because of social conflicts as the lives that are being lost in Ukraine and the most unfortunate thing seems to be the indifference in which many of us seem to carry the situation, “as long as, it does not affect me, my family, my friends, and my interests, it does not matter.” However, ev","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44664729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katherine A. Mafla-Ayub, Luisa F. Guzmán-Molano, Gabriel A. Centanaro-Meza, Jairo A. Mejia-Mójica
Post-polio syndrome (PPS) is a rare neurological disorder that affects 20-40% of paralytic and non-paralytic polio survivors. It is estimated that about 15 million people worldwide are survivors of the polio infection that occurred during the 1940s and 1950s, until the vaccine was first introduced. Its main characteristic is the appearance of de novo muscle weakness or its increase and atrophy, accompanied by other symptoms such as fatigue, joint, bone or muscle pain, intolerance to cold, and bulbar symptoms (involvement of swallowing, speech and breathing). PPS usually affects performance in daily activities with a negative effect on patients’ quality of life. We present two cases with a diagnosis of PPS, with a current review of the lit-erature.
{"title":"The legacy of polio: 2 cases of post-polio syndrome and review","authors":"Katherine A. Mafla-Ayub, Luisa F. Guzmán-Molano, Gabriel A. Centanaro-Meza, Jairo A. Mejia-Mójica","doi":"10.24875/rmn.20000147","DOIUrl":"https://doi.org/10.24875/rmn.20000147","url":null,"abstract":"Post-polio syndrome (PPS) is a rare neurological disorder that affects 20-40% of paralytic and non-paralytic polio survivors. It is estimated that about 15 million people worldwide are survivors of the polio infection that occurred during the 1940s and 1950s, until the vaccine was first introduced. Its main characteristic is the appearance of de novo muscle weakness or its increase and atrophy, accompanied by other symptoms such as fatigue, joint, bone or muscle pain, intolerance to cold, and bulbar symptoms (involvement of swallowing, speech and breathing). PPS usually affects performance in daily activities with a negative effect on patients’ quality of life. We present two cases with a diagnosis of PPS, with a current review of the lit-erature.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42658336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Aguilar-Fabré, R. Rodríguez-Valdés, L. Galán-García, J. Bosch-Bayard, H. Hernández-Montiel, Ramiro J. García-García
Purpose: This study was to deepen into the electro-clinical relationship and source analysis of absence seizures in childhood. Methods: Thirty-three subjects were studied with clinical and electrophysiological diagnosis of absence seizures without antiepileptic medication, video-electroencephalogram was applied. We obtained clinical behavior and electrophysiological variables during seizures and General Linear Model was applied, with p < 0.05. Source analysis was carried out with VARETA method. Results: 174 seizures were evaluated. 75.75% showed interictal epileptiform discharges (IED) and 12.12% showed posterior delta activity. There was an unequal behavior in relation with total electro-clinical seizures and presence or no of IED (p = 0.02), namely between subjects without IED in EEG and multifocal EEG (p = 0.008). Quantity of seizures recorded during HPV had a different behavior between subjects without IED in EEG and multifocal EEG (p = 0.03) and between focal and multifocal EEG (p = 0.04). Source analysis (VARETA) evidence the onset frontal of seizures in 57.47%, mesial and dorsolateral regions in 43% and 57%, respectively. Conclusion: These data suggest that absence seizures are not “generalized” if we considered global cortical activation but rather involve localized discharges from specific cortical regions, mainly frontal lobe.
{"title":"Electro-clinical relationship and source analysis of absence seizures in childhood","authors":"L. Aguilar-Fabré, R. Rodríguez-Valdés, L. Galán-García, J. Bosch-Bayard, H. Hernández-Montiel, Ramiro J. García-García","doi":"10.24875/rmn.21000049","DOIUrl":"https://doi.org/10.24875/rmn.21000049","url":null,"abstract":"Purpose: This study was to deepen into the electro-clinical relationship and source analysis of absence seizures in childhood. Methods: Thirty-three subjects were studied with clinical and electrophysiological diagnosis of absence seizures without antiepileptic medication, video-electroencephalogram was applied. We obtained clinical behavior and electrophysiological variables during seizures and General Linear Model was applied, with p < 0.05. Source analysis was carried out with VARETA method. Results: 174 seizures were evaluated. 75.75% showed interictal epileptiform discharges (IED) and 12.12% showed posterior delta activity. There was an unequal behavior in relation with total electro-clinical seizures and presence or no of IED (p = 0.02), namely between subjects without IED in EEG and multifocal EEG (p = 0.008). Quantity of seizures recorded during HPV had a different behavior between subjects without IED in EEG and multifocal EEG (p = 0.03) and between focal and multifocal EEG (p = 0.04). Source analysis (VARETA) evidence the onset frontal of seizures in 57.47%, mesial and dorsolateral regions in 43% and 57%, respectively. Conclusion: These data suggest that absence seizures are not “generalized” if we considered global cortical activation but rather involve localized discharges from specific cortical regions, mainly frontal lobe.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42973833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical thrombectomy in children: A little known and scarcely utilized resource","authors":"Y. Aburto-Murrieta, B. Mendez, J. Marquez-Romero","doi":"10.24875/rmn.21000033","DOIUrl":"https://doi.org/10.24875/rmn.21000033","url":null,"abstract":"","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42537067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent years, the control of physiological processes has been strengthened, which show metabolic changes that can generate effects at a neuronal level. Our objective is to review what has been described as conscious breathing theory and how this can affect cognitive tasks, which have been described as very affected in adults and which reduce with age. How-ever, we have begun to understand a new phenomenon of andragogic learning, which indicates that the task of learning must be understood differently, and that attention is something that must be understood as something that does not decrease with age but changes. It also seems that conscious breathing tasks can improve this type of task and that it can be beneficial. What has been published suggests that breathing, or at least conscious breathing exercise, improves certain cellular and neuronal capacities and that this can lead to real changes in cognitive tasks in adults.
{"title":"Systematic review and effect of conscious breathing on adult attention and learning task","authors":"V. Chavez, Lenin Ochoa-de-la-Paz, J. Parodi","doi":"10.24875/rmn.21000029","DOIUrl":"https://doi.org/10.24875/rmn.21000029","url":null,"abstract":"In recent years, the control of physiological processes has been strengthened, which show metabolic changes that can generate effects at a neuronal level. Our objective is to review what has been described as conscious breathing theory and how this can affect cognitive tasks, which have been described as very affected in adults and which reduce with age. How-ever, we have begun to understand a new phenomenon of andragogic learning, which indicates that the task of learning must be understood differently, and that attention is something that must be understood as something that does not decrease with age but changes. It also seems that conscious breathing tasks can improve this type of task and that it can be beneficial. What has been published suggests that breathing, or at least conscious breathing exercise, improves certain cellular and neuronal capacities and that this can lead to real changes in cognitive tasks in adults.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46911588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. A. Calderón-Chagualá, Miguel Á. Montilla-García, M. Gómez, Julián E. Ospina-Viña, Jennifer C. Triana-Martínez, Laura C. Vargas-Martínez
Palabras clave: Daño cerebral adquirido. Rehabilitación neuropsicológica. Realidad virtual. Rehabilitación tradicional. Rehabilitación. Fisioterapia. Abstract Neuropsychological rehabilitation is the discipline in charge of treating the cognitive, emotional and behavioral disorders that origi-nate as a result of brain damage, due to traumatic brain injury, hypoxia, stroke or tumors. We made a review of the tools for traditional and virtual neuropsychological rehabilitation, to determine the influence of each in the process of neuropsychological rehabilitation. The results revealed that two methods are reliable and valid in the processes of intervention for these kind of patients; however at the moment the virtual rehabilitation is generating easier access to this system, due to the creation of software specialized in rehabilitation. In conclusion, the review established that the two modalities are adequate, but the virtual modality has been developed for more integration of technological and scientific advances, resulting in improvement in a short time and with less cost.
{"title":"Rehabilitación neuropsicológica en daño cerebral: uso de herramientas tradicionales y realidad virtual","authors":"J. A. Calderón-Chagualá, Miguel Á. Montilla-García, M. Gómez, Julián E. Ospina-Viña, Jennifer C. Triana-Martínez, Laura C. Vargas-Martínez","doi":"10.24875/rmn.m22000089","DOIUrl":"https://doi.org/10.24875/rmn.m22000089","url":null,"abstract":"Palabras clave: Daño cerebral adquirido. Rehabilitación neuropsicológica. Realidad virtual. Rehabilitación tradicional. Rehabilitación. Fisioterapia. Abstract Neuropsychological rehabilitation is the discipline in charge of treating the cognitive, emotional and behavioral disorders that origi-nate as a result of brain damage, due to traumatic brain injury, hypoxia, stroke or tumors. We made a review of the tools for traditional and virtual neuropsychological rehabilitation, to determine the influence of each in the process of neuropsychological rehabilitation. The results revealed that two methods are reliable and valid in the processes of intervention for these kind of patients; however at the moment the virtual rehabilitation is generating easier access to this system, due to the creation of software specialized in rehabilitation. In conclusion, the review established that the two modalities are adequate, but the virtual modality has been developed for more integration of technological and scientific advances, resulting in improvement in a short time and with less cost.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47793967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the process of neurogenesis, which involves various stages, such as proliferation of neuronal stem cells, migration, differentiation, survival of new neurons, and integration of the same. Among the many intrinsic and extrinsic molecular signals that regulate the production of new neurons from progenitor cells in the adult in the central nervous system (CNS), hypoxic damage plays an important role in the maintenance and function of stem cells in development and disease.
{"title":"Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level","authors":"Clara L. Ramirez-Rincón","doi":"10.24875/rmn.21000020","DOIUrl":"https://doi.org/10.24875/rmn.21000020","url":null,"abstract":"Hypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the process of neurogenesis, which involves various stages, such as proliferation of neuronal stem cells, migration, differentiation, survival of new neurons, and integration of the same. Among the many intrinsic and extrinsic molecular signals that regulate the production of new neurons from progenitor cells in the adult in the central nervous system (CNS), hypoxic damage plays an important role in the maintenance and function of stem cells in development and disease.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43833004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Y Galvez-Contreras, Jorge Guzman-Muñiz, N. Moy-López, Ó. González-Pérez
Background: In Latin America, research in neuroscience and psychology has had a continuous development; however, the magnitude of this development and its impact on the comparison to other regions or countries has not been well studied. Objective: The objective of the study was to carry out a bibliometric analysis of scientific productivity in neuroscience and psychology in Latin America. Methods: We consulted the Scimago Journal and Country Rank database to obtain the clas-sification of the Latin American countries in these knowledge disciplines, during the period from 2015 to 2020. Results: We found 32 Latin American countries with citable documents in these disciplines. Notably, 90% of Latin American scientific productivity is concentrated in five countries: Brazil, Mexico, Argentina, Chile, and Colombia, with Brazil being the leading country in all cases. Conclusions: Research in neuroscience and psychology in Latin America has had a sustained and moderate growth. However, it is highly circumscribed in these five countries.
{"title":"Contributions of Latin America to scientific research in neuroscience and psychology","authors":"Alma Y Galvez-Contreras, Jorge Guzman-Muñiz, N. Moy-López, Ó. González-Pérez","doi":"10.24875/rmn.21000034","DOIUrl":"https://doi.org/10.24875/rmn.21000034","url":null,"abstract":"Background: In Latin America, research in neuroscience and psychology has had a continuous development; however, the magnitude of this development and its impact on the comparison to other regions or countries has not been well studied. Objective: The objective of the study was to carry out a bibliometric analysis of scientific productivity in neuroscience and psychology in Latin America. Methods: We consulted the Scimago Journal and Country Rank database to obtain the clas-sification of the Latin American countries in these knowledge disciplines, during the period from 2015 to 2020. Results: We found 32 Latin American countries with citable documents in these disciplines. Notably, 90% of Latin American scientific productivity is concentrated in five countries: Brazil, Mexico, Argentina, Chile, and Colombia, with Brazil being the leading country in all cases. Conclusions: Research in neuroscience and psychology in Latin America has had a sustained and moderate growth. However, it is highly circumscribed in these five countries.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47467451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}