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Aspects of neurodevelopment between autism spectrum disorders and epilepsy 自闭症谱系障碍和癫痫之间的神经发育方面
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-06-17 DOI: 10.24875/rmn.20000055
Paola Núñez-Contreras, Daniela Granado-Rocha, Maritza Carvajal-Game, Ana M. Torres-Perez
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引用次数: 0
Are different degrees of lymphopenia for FTY720 associated with serious infectious-type events? No 不同程度的FTY720淋巴细胞减少是否与严重的传染性事件相关?没有
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-04 DOI: 10.24875/rmn.21000048
Catalina Márquez-Martín, R. J. García-Bermúdez, B. Bertado-Cortés
Objective: Describing the occurrence of infections in patients with relapsing-remitting multiple sclerosis (RRMS) treated with fingolimod and with different degrees of lymphopenia in our unit. Patients and Methods: Observational, descriptive, longitudinal, and retrospective study in the Hospital Centro Médico Nacional Siglo XXI. Patients with RRMS and treatment with fingolimod were grouped based on lymphocyte count and infections. Quantitative variables were expressed as mean, standard deviation, and interquartile range;qualitative variables were expressed as frequencies and percentages. Results: 110 patients, 76 (69.1%) female, 34 (30.9%) male, mean age 38.3 years (17-63, SD 9.85). Mean of initial expanded disability status scale 1.59 (0-5.5, SD 1.15) with a mean diagnosis time of 63.6 months (3-252, SD 50.96). Prior to starting fingolimod, 90.09% of patients had lymphocyte count >1,000. At six months of treatment, 35.64% had lymphocyte >1,000. At twelve months 32.95% had lymphocyte from 501 to 700. At 24 months, 34.21% had lymphocyte from 701 to 1,000. Of the 110 patients, 31.8% had mild infections, of which pharyngitis was reported in 10%, gastroenteritis 2.7%, urinary tract infection 10.9%, HPV infection 0.9%, SARS-CoV-2 infection 3.6%, ophthalmic herpes 0.9%, molluscum contagiosum 0.9%, oral candidiasis 0.9%. 68.18% did not present infections of any kind, no serious infections were reported even with lymphocyte levels below 200. Conclusions: Selective lymphopenia caused by fingolimod was not associated with infections of any kind in this population even at levels of 200-500 cells/mm³. (English) [ FROM AUTHOR] Objetivo: Describir la ocurrencia de infecciones severas en pacientes con EMRR tratados con fingolimod y con diferentes grados de linfopenia en nuestra unidad Métodos: Estudio observacional, descriptivo, longitudinal y retrospectivo realizado en el Hospital Centro Médico Nacional Siglo XXI. Pacientes con EMRR tratados con fingolimod, se agruparon por grados de linfopenia e infecciones. Las variables cuantitativas se expresaron como media, desviación estándar y rango intercuartil;las variables cualitativas se expresaron en frecuencias y porcentajes. Resultados: 110 pacientes, 76 mujeres (69.1%), 34 hombres (30.9%), media de edad 38.39 (17-63 DE 9.85). Media EDSS inicial 1.59 (0-5.5, DE 1.15), tiempo diagnóstico medio 63.67 meses (3-252, DE 50.96). Previo al inicio de fingolimod, 90.09% de los pacientes tenía linfocitos absolutos >1,000. A los 6 meses de tratamiento, 35.64% tenía >1,000 linfocitos. A los 12 meses el 32.95% tenía 501-700 linfocitos, a los 24 meses el 34.21% tenía 701-1,000 linfocitos. De los 110 pacientes, el 31.8% presentó infecciones leves, de las cuales se informó faringitis en 10%, gastroenteritis 2.7%, infección del tracto urinario 10.9%, infección por VPH 0.9%, infección por SARS-CoV-2 3.6%, herpes oftálmico 0.9%, molusco contagioso 0.9%, candidiasis oral 0.9%. El 68.18% no presentó infecciones de ningún tipo, no se
目的:了解本单位不同程度淋巴细胞减少的芬戈莫德治疗的复发-缓解型多发性硬化症(RRMS)患者感染发生情况。患者和方法:观察性、描述性、纵向和回顾性研究,在21世纪国立马姆萨迪科医院中心进行。根据淋巴细胞计数和感染情况对RRMS患者进行分组。定量变量用均值、标准差、四分位间距表示;定性变量用频率、百分比表示。结果:110例患者中,女性76例(69.1%),男性34例(30.9%),平均年龄38.3岁(17 ~ 63岁,SD 9.85)。初始扩展残疾状态量表平均1.59 (0 ~ 5.5,SD 1.15),平均诊断时间63.6个月(3 ~ 252,SD 50.96)。在开始使用芬戈莫德之前,90.09%的患者淋巴细胞计数为100 000。治疗6个月时淋巴细胞计数为35.64%。12个月时淋巴细胞501 ~ 700,32.95%。24个月时淋巴细胞701 ~ 1000的占34.21%。110例患者中,轻度感染占31.8%,其中咽炎占10%,胃肠炎占2.7%,尿路感染占10.9%,HPV感染占0.9%,SARS-CoV-2感染占3.6%,眼部疱疹占0.9%,传染性软疣占0.9%,口腔念珠菌病占0.9%。68.18%的患者未出现任何感染,即使淋巴细胞水平低于200也未出现严重感染。结论:芬戈莫德引起的选择性淋巴细胞减少与该人群中任何类型的感染无关,即使在200-500细胞/mm³的水平。摘要目的:描述 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -感染EMRR的患者通常有两种症状,一种是慢性肺炎,一种是慢性肺炎,另一种是慢性肺炎。两个变量定量地表示不同媒介之间的关系,desviación estándar表示不同媒介之间的关系;两个变量定性地表示不同媒介之间的关系,频率表示不同媒介之间的关系。结果:患者110例,女性76例(69.1%),男性34例(30.9%),媒介38.39例(17-63 de 9.85)。Media EDSS初始值1.59 (0-5.5,DE 1.15), timempo diagnóstico medio 63.67 meses (3-252, DE 50.96)。Previo al inicio de fingolimod, 90.09% de los pacites tenía linfocitos absolutos 100 000。A亏损6个meses de tramiento, 35.64% tenía bbb10 000户。A有12个展位展位32.95% tenía 501-700个展位,24个展位34.21% tenía 701- 1000个展位。110例患者中,el 31.8% presentó感染水平,las cuales se informó细菌性肠炎10%,肠胃炎2.7%,infección尿路性肠炎10.9%,infección VPH差0.9%,infección SARS-CoV-2差3.6%,疱疹oftálmico 0.9%,传染性软足病0.9%,口腔念珠菌病0.9%。1 68.18%未发现presentó感染(ningún tipo),未发现reportó感染(包括linfocitos inferires)(200)。结论:青光眼选择性致病菌可导致青光眼病变asoció,感染数例青光眼病变población,发病例数为200 ~ 500 ccxlulas /mm³。(西班牙语)[来自作者]Revista Mexicana de Neurociencia版权归墨西哥神经科学院所有,未经版权所有者明确书面许可,不得将其内容复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
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引用次数: 0
We are at war 我们处于战争状态
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-03 DOI: 10.24875/rmn.m22000086
Ildefonso Rodríguez-Leyva
Correspondence: *Ildefonso Rodríguez-Leyva E-mail: ilrole@yahoo.com.mx Available online: 02-05-2022 Rev Mex Neuroci. 2022;23(3):79 www.revmexneurociencia.com Date of reception: 04-03-2022 Date of acceptance: 04-03-2022 DOI: 10.24875/RMN.M22000086 The difficult situation that humanity faces when one part of it confronts another could be compared to a social disease. Without having yet emerged from a pandemic, we are now facing another conflict that will have an impact on mortality and the global economy. War is a social conflict that goes with the same history of humanity and it is usually experienced not only between nations but also within each country, each small society, and even within families. Neurologists often find it necessary to certify that the patriarch or the mother of a family is unable to make decisions due to a fixed or progressive cognitive deterioration, while the children break their ties out of economic ambition or simply for the sake of power. The same happens in social groups, organizations, and societies. The quest to have more, the envy, the desire to transcend or to feel powerful makes people’s and nations’ leaders to be both admired and hated at the same time. The followers will applaud the aggressions, while the opponents will mark distance and will try to convince others about the unfairness of the warlike maneuver that the leader is exercising. The same happens with organizations: the representative tends to forget those who supported him and exercises their power by rewarding those close to them, their friends, and cornering those who dare to raise their voices demanding justice or at least space. Are these social struggles a reflection of the illness of a leader who tries to exercise his will? The answer is not simple, justice has its edges and what is valid in one society may be punished in another, what is logical and adequate for one group may be crushing and impoverishing for another. What I believe is always terrible, no matter which perspective it belongs to, is the loss of lives that were not even participating or had minimal interest in the conflict generated, as well as the fact that people have to leave their homes, their homeland, and their family, for the interest of others. It is unfortunate to have to leave a whole history, belongings, and memories behind or to have them destroyed by someone who feels superior because they carry a weapon. In what area of our brain does the war process initiate? There is no doubt that this is the organ that creates good and bad actions, the one generates envy, ambition, destruction, and war. Countries like ours are living their own war, as incredible as it may seem, as many people die because of social conflicts as the lives that are being lost in Ukraine and the most unfortunate thing seems to be the indifference in which many of us seem to carry the situation, “as long as, it does not affect me, my family, my friends, and my interests, it does not matter.” However, ev
通讯:*Ildefonso Rodríguez Leyva电子邮件:ilrole@yahoo.com.mx可在线获取:02-05-2022 Rev Mex Neuroci。2022年;23(3):79 www.revmexcneuriciencia.com接收日期:2022年4月3日接受日期:2022月4日DOI:10.24875/RMN.M22000086当人类的一部分面对另一部分时,人类面临的困难可以比作一种社会疾病。在尚未摆脱疫情的情况下,我们现在面临着另一场冲突,这场冲突将对死亡率和全球经济产生影响。战争是一场与人类历史相同的社会冲突,它通常不仅发生在国家之间,而且发生在每个国家、每个小社会甚至家庭内部。神经学家经常发现有必要证明,一个家庭的家长或母亲由于固定或渐进的认知退化而无法做出决定,而孩子们则出于经济野心或仅仅为了权力而断绝关系。同样的情况也发生在社会团体、组织和社会中。追求更多、嫉妒、超越或感觉强大的欲望使人民和国家的领导人同时受到钦佩和憎恨。追随者会为侵略行为鼓掌,而反对者则会标记距离,并试图说服其他人相信领导人所采取的好战策略的不公平性。组织也会发生同样的情况:代表往往会忘记那些支持他的人,并通过奖励亲近的人、他们的朋友来行使他们的权力,并压制那些敢于发声要求正义或至少空间的人。这些社会斗争是否反映了一位试图行使自己意志的领导人的疾病?答案并不简单,正义有其优势,在一个社会中有效的东西可能会在另一个社会受到惩罚,对一个群体来说合乎逻辑和足够的东西可能对另一个群体造成毁灭和贫困。我认为,无论从哪个角度来看,总是可怕的是,那些甚至没有参与或对所产生的冲突兴趣最小的人的生命损失,以及人们为了他人的利益而不得不离开家园、家园和家人的事实。不幸的是,不得不留下整个历史、财产和记忆,或者因为他们携带武器而被感觉优越的人摧毁。战争过程在我们大脑的哪个区域开始?毫无疑问,这是创造好的和坏的行为的器官,是产生嫉妒、野心、毁灭和战争的器官。像我们这样的国家正在经历自己的战争,尽管这看起来很不可思议,因为社会冲突而死亡的人和在乌克兰失去的生命一样多,最不幸的是,我们中的许多人似乎对这种情况漠不关心,“只要这不影响我、我的家人、我的朋友和我的利益,这都无关紧要。”然而,每一次社会变革最终都会影响到我们,这就是为什么我们必须坚持寻找真相是解决我们所面临的每一个社会不公的唯一答案。教育是理解尊重他人、宽容、共存以及以其他方式看待现实的重要性的最佳方式。正是看到了另一个人的视角,才让我们明白我的想法可能是错误的,我可能是错的。在这份出版物中,我们向那些正在遭受失去亲人、家园、家园和过去的痛苦的人表示声援,我们希望我们的社会将受到更多的教育,更加公平、富有成效、健康和公正。我们祝愿世界和平,尤其是那些处于战争中的人们。
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引用次数: 0
The legacy of polio: 2 cases of post-polio syndrome and review 脊髓灰质炎的遗产:脊髓灰质炎后综合征2例及回顾
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-03 DOI: 10.24875/rmn.20000147
Katherine A. Mafla-Ayub, Luisa F. Guzmán-Molano, Gabriel A. Centanaro-Meza, Jairo A. Mejia-Mójica
Post-polio syndrome (PPS) is a rare neurological disorder that affects 20-40% of paralytic and non-paralytic polio survivors. It is estimated that about 15 million people worldwide are survivors of the polio infection that occurred during the 1940s and 1950s, until the vaccine was first introduced. Its main characteristic is the appearance of de novo muscle weakness or its increase and atrophy, accompanied by other symptoms such as fatigue, joint, bone or muscle pain, intolerance to cold, and bulbar symptoms (involvement of swallowing, speech and breathing). PPS usually affects performance in daily activities with a negative effect on patients’ quality of life. We present two cases with a diagnosis of PPS, with a current review of the lit-erature.
脊髓灰质炎后综合征(PPS)是一种罕见的神经系统疾病,影响20-40%的麻痹性和非麻痹性脊髓灰质炎幸存者。据估计,在疫苗首次推出之前,全世界约有1500万人是20世纪40年代和50年代脊髓灰质炎感染的幸存者。其主要特征是出现新发性肌无力或其增加和萎缩,并伴有其他症状,如疲劳、关节、骨骼或肌肉疼痛、对寒冷的不耐受和延髓症状(包括吞咽、言语和呼吸)。PPS通常会影响日常活动的表现,对患者的生活质量产生负面影响。我们报告了两例诊断为PPS的病例,并对其进行了最新的回顾。
{"title":"The legacy of polio: 2 cases of post-polio syndrome and review","authors":"Katherine A. Mafla-Ayub, Luisa F. Guzmán-Molano, Gabriel A. Centanaro-Meza, Jairo A. Mejia-Mójica","doi":"10.24875/rmn.20000147","DOIUrl":"https://doi.org/10.24875/rmn.20000147","url":null,"abstract":"Post-polio syndrome (PPS) is a rare neurological disorder that affects 20-40% of paralytic and non-paralytic polio survivors. It is estimated that about 15 million people worldwide are survivors of the polio infection that occurred during the 1940s and 1950s, until the vaccine was first introduced. Its main characteristic is the appearance of de novo muscle weakness or its increase and atrophy, accompanied by other symptoms such as fatigue, joint, bone or muscle pain, intolerance to cold, and bulbar symptoms (involvement of swallowing, speech and breathing). PPS usually affects performance in daily activities with a negative effect on patients’ quality of life. We present two cases with a diagnosis of PPS, with a current review of the lit-erature.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42658336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electro-clinical relationship and source analysis of absence seizures in childhood 儿童失神性癫痫的电临床关系及病因分析
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-03 DOI: 10.24875/rmn.21000049
L. Aguilar-Fabré, R. Rodríguez-Valdés, L. Galán-García, J. Bosch-Bayard, H. Hernández-Montiel, Ramiro J. García-García
Purpose: This study was to deepen into the electro-clinical relationship and source analysis of absence seizures in childhood. Methods: Thirty-three subjects were studied with clinical and electrophysiological diagnosis of absence seizures without antiepileptic medication, video-electroencephalogram was applied. We obtained clinical behavior and electrophysiological variables during seizures and General Linear Model was applied, with p < 0.05. Source analysis was carried out with VARETA method. Results: 174 seizures were evaluated. 75.75% showed interictal epileptiform discharges (IED) and 12.12% showed posterior delta activity. There was an unequal behavior in relation with total electro-clinical seizures and presence or no of IED (p = 0.02), namely between subjects without IED in EEG and multifocal EEG (p = 0.008). Quantity of seizures recorded during HPV had a different behavior between subjects without IED in EEG and multifocal EEG (p = 0.03) and between focal and multifocal EEG (p = 0.04). Source analysis (VARETA) evidence the onset frontal of seizures in 57.47%, mesial and dorsolateral regions in 43% and 57%, respectively. Conclusion: These data suggest that absence seizures are not “generalized” if we considered global cortical activation but rather involve localized discharges from specific cortical regions, mainly frontal lobe.
目的:本研究旨在加深儿童失神性癫痫的临床电生理关系和来源分析。方法:采用视频脑电图对33例癫痫患者在未服用抗癫痫药物的情况下进行缺席发作的临床和电生理诊断。我们获得了癫痫发作期间的临床行为和电生理变量,并应用了一般线性模型,p<0.05。采用VARETA方法进行来源分析。结果:174次癫痫发作得到评估。75.75%表现为发作间期癫痫样放电(IED),12.12%表现为后三角洲活动。与临床总癫痫发作和IED的存在或不存在相关的行为不平等(p=0.02),即EEG中没有IED的受试者和多焦EEG之间(p=0.008)。HPV期间记录的癫痫发作量在EEG和多焦脑电图中无IED的被试者之间(p=0.03)以及在焦和多焦脑电之间(p=0.04)具有不同的行为。来源分析(VARETA)证明,发作的额叶发作率为57.47%,内侧和背外侧区域分别为43%和57%。结论:这些数据表明,如果我们考虑整体皮层激活,缺席发作并不是“普遍的”,而是涉及特定皮层区域(主要是额叶)的局部放电。
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引用次数: 0
Mechanical thrombectomy in children: A little known and scarcely utilized resource 儿童机械取栓:一种鲜为人知且很少使用的资源
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-03 DOI: 10.24875/rmn.21000033
Y. Aburto-Murrieta, B. Mendez, J. Marquez-Romero
{"title":"Mechanical thrombectomy in children: A little known and scarcely utilized resource","authors":"Y. Aburto-Murrieta, B. Mendez, J. Marquez-Romero","doi":"10.24875/rmn.21000033","DOIUrl":"https://doi.org/10.24875/rmn.21000033","url":null,"abstract":"","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42537067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review and effect of conscious breathing on adult attention and learning task 有意识呼吸对成人注意力和学习任务的影响及系统评价
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-05-03 DOI: 10.24875/rmn.21000029
V. Chavez, Lenin Ochoa-de-la-Paz, J. Parodi
In recent years, the control of physiological processes has been strengthened, which show metabolic changes that can generate effects at a neuronal level. Our objective is to review what has been described as conscious breathing theory and how this can affect cognitive tasks, which have been described as very affected in adults and which reduce with age. How-ever, we have begun to understand a new phenomenon of andragogic learning, which indicates that the task of learning must be understood differently, and that attention is something that must be understood as something that does not decrease with age but changes. It also seems that conscious breathing tasks can improve this type of task and that it can be beneficial. What has been published suggests that breathing, or at least conscious breathing exercise, improves certain cellular and neuronal capacities and that this can lead to real changes in cognitive tasks in adults.
近年来,对生理过程的控制得到了加强,这表明代谢变化可以在神经元水平上产生影响。我们的目标是回顾被称为有意识呼吸理论的理论,以及它如何影响认知任务,认知任务在成年人中被描述为非常受影响,并且随着年龄的增长而减少。然而,我们已经开始理解一种新的学习现象,这表明必须以不同的方式理解学习任务,并且必须将注意力理解为不会随着年龄的增长而减少而是变化的东西。有意识的呼吸任务似乎也能改善这类任务,而且是有益的。已经发表的研究表明,呼吸,或者至少是有意识的呼吸练习,可以提高某些细胞和神经元的能力,这可能会导致成年人认知任务的真正变化。
{"title":"Systematic review and effect of conscious breathing on adult attention and learning task","authors":"V. Chavez, Lenin Ochoa-de-la-Paz, J. Parodi","doi":"10.24875/rmn.21000029","DOIUrl":"https://doi.org/10.24875/rmn.21000029","url":null,"abstract":"In recent years, the control of physiological processes has been strengthened, which show metabolic changes that can generate effects at a neuronal level. Our objective is to review what has been described as conscious breathing theory and how this can affect cognitive tasks, which have been described as very affected in adults and which reduce with age. How-ever, we have begun to understand a new phenomenon of andragogic learning, which indicates that the task of learning must be understood differently, and that attention is something that must be understood as something that does not decrease with age but changes. It also seems that conscious breathing tasks can improve this type of task and that it can be beneficial. What has been published suggests that breathing, or at least conscious breathing exercise, improves certain cellular and neuronal capacities and that this can lead to real changes in cognitive tasks in adults.","PeriodicalId":53921,"journal":{"name":"Revista Mexicana de Neurociencia","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46911588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rehabilitación neuropsicológica en daño cerebral: uso de herramientas tradicionales y realidad virtual 脑损伤的神经心理康复:传统工具和虚拟现实的使用
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-04-05 DOI: 10.24875/rmn.m22000089
J. A. Calderón-Chagualá, Miguel Á. Montilla-García, M. Gómez, Julián E. Ospina-Viña, Jennifer C. Triana-Martínez, Laura C. Vargas-Martínez
Palabras clave: Daño cerebral adquirido. Rehabilitación neuropsicológica. Realidad virtual. Rehabilitación tradicional. Rehabilitación. Fisioterapia. Abstract Neuropsychological rehabilitation is the discipline in charge of treating the cognitive, emotional and behavioral disorders that origi-nate as a result of brain damage, due to traumatic brain injury, hypoxia, stroke or tumors. We made a review of the tools for traditional and virtual neuropsychological rehabilitation, to determine the influence of each in the process of neuropsychological rehabilitation. The results revealed that two methods are reliable and valid in the processes of intervention for these kind of patients; however at the moment the virtual rehabilitation is generating easier access to this system, due to the creation of software specialized in rehabilitation. In conclusion, the review established that the two modalities are adequate, but the virtual modality has been developed for more integration of technological and scientific advances, resulting in improvement in a short time and with less cost.
Palabras clave: Daño脑内静脉曲张。Rehabilitacion neuropsicologica。Realidad虚拟。Rehabilitacion tradicional。Rehabilitacion。Fisioterapia。神经心理康复是一门治疗因创伤性脑损伤、缺氧、中风或肿瘤引起的脑损伤而引起的认知、情绪和行为障碍的学科。我们对传统神经心理康复和虚拟神经心理康复的工具进行了综述,以确定每种工具在神经心理康复过程中的影响。结果表明,两种方法在对该类患者的干预过程中是可靠有效的;然而,由于专门从事康复的软件的创建,目前虚拟康复正在产生更容易进入这个系统。最后,审查确定,这两种模式是适当的,但虚拟模式已经发展,以便更多地整合技术和科学进步,从而在短时间内以更少的成本进行改进。
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引用次数: 1
Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level 缺氧诱导因子(HIF)在海马水平神经发生过程中的作用
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-02-22 DOI: 10.24875/rmn.21000020
Clara L. Ramirez-Rincón
Hypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the process of neurogenesis, which involves various stages, such as proliferation of neuronal stem cells, migration, differentiation, survival of new neurons, and integration of the same. Among the many intrinsic and extrinsic molecular signals that regulate the production of new neurons from progenitor cells in the adult in the central nervous system (CNS), hypoxic damage plays an important role in the maintenance and function of stem cells in development and disease.
缺氧诱导因子1 (hypoxia induced factor 1, HIF-1)在低氧应激反应中起着至关重要的作用,因为它调节多种基因的表达,其产物参与血管生成、能量代谢、红细胞生成和细胞增殖等过程,以及神经发生过程,涉及神经干细胞的增殖、迁移、分化、新神经元的存活和整合等各个阶段。在调节成人中枢神经系统(CNS)祖细胞产生新神经元的许多内在和外在分子信号中,缺氧损伤在干细胞发育和疾病中的维持和功能中起着重要作用。
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引用次数: 0
Contributions of Latin America to scientific research in neuroscience and psychology 拉丁美洲对神经科学和心理学科学研究的贡献
IF 0.2 Q4 CLINICAL NEUROLOGY Pub Date : 2022-02-22 DOI: 10.24875/rmn.21000034
Alma Y Galvez-Contreras, Jorge Guzman-Muñiz, N. Moy-López, Ó. González-Pérez
Background: In Latin America, research in neuroscience and psychology has had a continuous development; however, the magnitude of this development and its impact on the comparison to other regions or countries has not been well studied. Objective: The objective of the study was to carry out a bibliometric analysis of scientific productivity in neuroscience and psychology in Latin America. Methods: We consulted the Scimago Journal and Country Rank database to obtain the clas-sification of the Latin American countries in these knowledge disciplines, during the period from 2015 to 2020. Results: We found 32 Latin American countries with citable documents in these disciplines. Notably, 90% of Latin American scientific productivity is concentrated in five countries: Brazil, Mexico, Argentina, Chile, and Colombia, with Brazil being the leading country in all cases. Conclusions: Research in neuroscience and psychology in Latin America has had a sustained and moderate growth. However, it is highly circumscribed in these five countries.
背景:在拉丁美洲,神经科学和心理学的研究一直在不断发展;然而,这一发展的规模及其对与其他区域或国家比较的影响尚未得到很好的研究。目的:本研究的目的是对拉丁美洲神经科学和心理学的科学生产力进行文献计量学分析。方法:查阅sciago Journal和Country Rank数据库,获取2015 - 2020年拉美国家在这些知识学科中的分类情况。结果:我们在这些学科中发现了32个拉丁美洲国家可引用的文献。值得注意的是,拉丁美洲90%的科学生产力集中在五个国家:巴西、墨西哥、阿根廷、智利和哥伦比亚,其中巴西在所有情况下都处于领先地位。结论:拉丁美洲的神经科学和心理学研究有持续和适度的增长。然而,在这五个国家,它受到高度限制。
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引用次数: 2
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Revista Mexicana de Neurociencia
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