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Factorial Design of Experiment Method to Characterize Bioprinting Process Parameters to Obtain the Targeted Scaffold Porosity 表征生物打印工艺参数以获得目标支架孔隙度的实验方法的析因设计
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-11-01 DOI: 10.1089/3dp.2023.0138
Connor Quigley, Shah M. Limon, Rokeya Sarah, Ahasan Habib
Due to its inbuilt ability to release biocompatible materials encapsulating living cells in a predefined location, 3D bioprinting is a promising technique for regenerating patient-specific tissues and organs. Among various 3D bioprinting techniques, extrusion-based 3D bioprinting ensures a higher percentage of cell release, ensuring suitable external and internal scaffold architectures. Scaffold architecture is mainly defined by filament geometry and width. A systematic selection of a set of process parameters, such as nozzle diameter, print speed, print distance, extrusion pressure, and material viscosity, can control the filament geometry and width, eventually confirming the user-defined scaffold porosity. For example, carefully selecting two sets of process parameters can result in a similar filament width (FW). However, the lack of availability of sufficient analytical relationships between printing process parameters and FW creates a barrier to achieving defined scaffold architectures with available resources. In this article, the factorial design of experiment (DoE) method has been adopted to obtain a relationship among scaffold properties that is, FW with 3D printing process parameters. The FW was determined using an image processing technique and an analytical relationship was developed, including various process parameters to maintain defined FW variation for different hydrogels within an acceptable range to confirm the overall geometric fidelity of the scaffold. The validation experiment results showed that our analytical relationship obtained from the DoE effectively predicts the scaffold's architectural property. Furthermore, the proposed analytical relationships can help achieve defined scaffold architectures with available resources.
由于其内在的能力,释放生物相容性材料封装活细胞在预定的位置,3D生物打印是一个有前途的技术再生患者特异性组织和器官。在各种生物3D打印技术中,基于挤压的生物3D打印确保了更高的细胞释放百分比,确保了合适的外部和内部支架结构。脚手架结构主要由灯丝的几何形状和宽度来定义。系统选择一组工艺参数,如喷嘴直径、打印速度、打印距离、挤出压力和材料粘度,可以控制长丝的几何形状和宽度,最终确定用户定义的支架孔隙率。例如,仔细选择两组工艺参数可以得到相似的长丝宽度(FW)。然而,打印工艺参数和FW之间缺乏足够的分析关系,这对利用现有资源实现明确的支架结构造成了障碍。本文采用试验析因设计(DoE)方法,得到支架性能与3D打印工艺参数之间的关系,即FW与3D打印工艺参数之间的关系。使用图像处理技术确定FW,并建立了分析关系,包括各种工艺参数,以使不同水凝胶的FW变化保持在可接受的范围内,以确认支架的整体几何保真度。验证实验结果表明,从DoE得到的分析关系可以有效地预测支架的结构性能。此外,提出的分析关系可以帮助利用可用资源实现定义的支架结构。
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引用次数: 0
Mechanical Characterization of Polylactic Acid Composite Scaffolds Formed in Different Lattice Structures by Fused Deposition Modeling-Based 3D Printing 基于熔融沉积建模的3D打印不同晶格结构聚乳酸复合材料支架的力学特性
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-30 DOI: 10.1089/3dp.2023.0188
Bora Uzun
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引用次数: 0
Effect of Combined Direct Current Electric Field and Pulsed Magnetic Field on the Transient Melt Pool in Laser Additive Manufacturing Process 直流电场和脉冲磁场对激光增材制造过程中瞬态熔池的影响
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-30 DOI: 10.1089/3dp.2023.0027
Chao Zeng, Fang Huang, Jiutian Xue, Yun Jia, Jianxing Hu
The application of a pulsed magnetic field (PMF) during a metallurgy solidification process has proven to be an effective method in refining the grain size and improving the mechanical performance of the material. However, fewer works were reported in the realm of laser additive manufacturing (LAM) and the mechanism of grain refinement consequent to the PMF is still unclear. In this work, numerical models were developed to study the thermal-fluid characteristics in the Ti-alloy melt pool generated during the laser scanning process under the effect of a combined direct current (DC) electric field and PMF. The temperature field and magneto-oscillation effect in the melt pool were discussed to elucidate the resultant microstructure evolution. The results show that the application of a combined DC electric field and PMF could decrease the maximum temperature in the melt pool, but increase the temperature gradient at the liquid-solid interface. The electric-magnetic field can lead to a notable increase in the magnitude of the fluid velocity and a greater fluctuation in the magnitude. A more refined microstructure is expected to be obtained, of which the mechanism may be ascribed to not only the increased temperature gradient, solidification growth rate, and cooling rate at the liquid-solid interface but also the enhanced fluid convection and continuous impulse force in the melt. For better grain refinement, the preferable duty cycles of the PMF should be <50%. The findings of this study may give a new insight into the electromagnetic controlling methods for LAM of Ti-alloy parts.
在冶金凝固过程中施加脉冲磁场是细化晶粒尺寸和提高材料力学性能的有效方法。然而,在激光增材制造(LAM)领域的研究较少,PMF导致晶粒细化的机制尚不清楚。本文建立了数值模型,研究了在直流电场和PMF联合作用下激光扫描过程中钛合金熔池的热流体特性。讨论了熔池的温度场和磁振荡效应,阐明了熔池的微观组织演变。结果表明:直流电场与PMF联合作用可降低熔池最高温度,但增大液固界面温度梯度;电磁场的作用会导致流体速度的幅度显著增大,幅度波动较大。期望得到更精细的微观组织,其机制可能是由于温度梯度、凝固生长速度和液固界面冷却速度的增加,以及熔体中流体对流和持续冲力的增强。为了更好地细化晶粒,PMF的优选占空比应小于50%。本研究结果为钛合金零件的电磁控制提供了新的思路。
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引用次数: 0
Fabrication of Piezoelectric Structures with High Porosity by Digital Light Processing 数字光处理制备高孔隙率压电结构
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-30 DOI: 10.1089/3dp.2023.0079
Dongcai Zhang, Yaodong Yang, Xuhan Lv, Wei-Feng Rao
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引用次数: 0
Fabrication Strategy of Additively Manufactured Metal Mirror Based on Multi-Load Topology Optimization and Single-Point Diamond Turning 基于多载荷拓扑优化和单点金刚石车削的增材制造金属镜面加工策略
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-27 DOI: 10.1089/3dp.2023.0106
Qianglong Wang, Chong Wang, Yisheng Chen, Luchao Cheng, Chen Liu, Wenda Niu, Jitong Zhao, Zhiyu Zhang, Zhenyu Liu
This article presents a fabrication strategy on the structural design, optimization, additive manufacturing, and processing of metal mirror. Specifically, the study showcases the topology design of a metal mirror with diameter of 200 mm, the additive manufacturing of standard aluminum-based powder (AlSi10Mg), the high-precision single-point diamond turning process of the surface. By setting the feasible domain partition, a topology optimization model suitable for metal additive manufacturing and subsequent surface shaping was constructed, which takes into account the multi-load machining load conditions of single-point diamond turning technology and the material topology representation of standard support structures for additive manufacturing. The results demonstrate that the optimization model effectively suppresses the vibration phenomenon during single-point cutting. Furthermore, the results of the optical interferometer surface inspection confirm that the design and processing strategy for additively manufactured metal mirrors demonstrated in this study can be directly applied to infrared band reflective imaging optical systems.
本文介绍了金属反射镜的结构设计、优化、增材制造和加工的制造策略。具体而言,研究展示了直径为200 mm的金属反射镜的拓扑设计,标准铝基粉末(AlSi10Mg)的增材制造,表面的高精度单点金刚石车削工艺。通过设定可行域划分,考虑单点金刚石车削技术的多载荷加工载荷条件和增材制造标准支撑结构的材料拓扑表示,构建了适合金属增材制造及其后续表面成形的拓扑优化模型。结果表明,该优化模型有效地抑制了单点切削时的振动现象。此外,光学干涉仪表面检测的结果证实了本研究所证明的增材制造金属反射镜的设计和加工策略可以直接应用于红外波段反射成像光学系统。
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引用次数: 0
Numerical Homogenization Calculation of Effective Stiffness of Fused Deposition Modeling Printing Carbon Fiber Reinforced Polylactic Acid Composites 熔融沉积成型打印碳纤维增强聚乳酸复合材料有效刚度的数值均匀化计算
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-19 DOI: 10.1089/3dp.2023.0131
Mingju Lei, Yanen Wang, Qinghua Wei, Mingyang Li, Juan Zhang, Yanmei Wang
The varied material and the inherent complex microstructure make predicting the effective stiffness of fused deposition modeling (FDM) printed polylactic acid (PLA)/carbon fiber (CF) composite a troublesome problem. This article proposes a microstructure scanning electron microscope (SEM) mapping modeling and numerical mean procedure to calculate the effective stiffness of FDM printing PLA/CF laminates. The printed PLA/CF parts were modeled as a continuum of 3D uniform linear elasticity with orthotropic anisotropy, and their elastic behavior was characterized by orthotropic constitutive relations. Micromechanical models of two typical deposition configurations, 0° unidirectional aligned configuration and 0°/90° angle-ply configuration of the printed parts were established based on the periodic representative volume element (RVE) technique. The elastic constants of the RVE models were estimated by volume average method in the finite element stress analysis, and the effects of deposition configurations, CF length, and content on the effective stiffness were also investigated. The results show that the effective stiffness of FDM printing PLA/CF composite is closely related to CF length, content, and the deposition configuration. With the increase of CF length and content, the Young's modulus and shear modulus of printed PLA/CF parts increase, whereas Poisson's ratio decreases. The printed PLA/CF parts with 0° unidirectional aligned configuration exhibits orthotropic characteristics, and the maximum Young's modulus appears along the first axis. The 0°/90° angle-ply FDM PLA/CF composite exhibits transverse isotropic characteristics and the lowest Young's modulus is found along the thickness direction.
材料的多样性和其固有的复杂微观结构使得熔融沉积建模(FDM)打印聚乳酸/碳纤维复合材料的有效刚度预测成为一个棘手的问题。本文提出了一种微结构扫描电镜(SEM)映射建模和数值平均方法来计算FDM打印PLA/CF层合板的有效刚度。将PLA/CF打印件建模为具有正交各向异性的三维均匀线弹性连续体,其弹性行为采用正交各向异性本构关系表征。基于周期性代表性体积元(RVE)技术,建立了0°单向排列和0°/90°夹角铺层两种典型沉积结构的微观力学模型。在有限元应力分析中,采用体积平均法估算了RVE模型的弹性常数,并研究了沉积形态、CF长度和含量对有效刚度的影响。结果表明:FDM打印PLA/CF复合材料的有效刚度与CF长度、含量和沉积形态密切相关;随着CF长度和含量的增加,PLA/CF打印件的杨氏模量和剪切模量增大,泊松比减小。打印的0°单向排列的PLA/CF零件具有正交异性,最大杨氏模量出现在第一个轴上。0°/90°角层FDM PLA/CF复合材料具有横向各向同性,杨氏模量沿厚度方向最低。
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引用次数: 0
Development of Bioinspired Biphasic Calcium Phosphate Inks for Manufacturing Bone Scaffolds by Robocasting 仿生磷酸钙双相墨水在骨支架制造中的应用
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-19 DOI: 10.1089/3dp.2023.0082
Samira Tajvar, Afra Hadjizadeh, Saeed Saber Samandari
Robocasting calcium phosphate compounds as a novel approach to creating customized structures with interconnected pores not only overcomes the limitations of traditional fabrication methods of calcium phosphate substitutes but also boosts the potential for bone tissue regeneration. The ink development is a key step in 3D printing. In this study, different inks consisting of magnesium- and sodium-doped carbonated hydroxyapatite, β-tricalcium phosphate, and Pluronic F-127 were prepared to design biomimetic bone scaffolds. To achieve suitable printability and subsequently, structures with high shape fidelity and appropriate mechanical properties, the selected compositions were evaluated by rheological analysis and mechanical tests. The results demonstrated that the prepared inks exhibited shear thinning behavior, and by increasing the concentration of Pluronic and biphasic calcium phosphate (BCP), more consistent gels were obtained that were able to maintain their shape after printing. The compressive strength of the scaffolds varied in the range of ∼8–60 MPa. The morphology of the sintered scaffolds in the scanning electron microscopy images also showed a dual macro- and micropore-size architecture, which can promote the adhesion of proteins and cell behavior. Our findings indicated that bioinspired BCP scaffolds can be fabricated with relatively high precision for use as cancellous bone substitutes.
机械铸造磷酸钙化合物作为一种具有相互连接孔的定制结构的新方法,不仅克服了传统磷酸钙替代品制造方法的局限性,而且提高了骨组织再生的潜力。墨水的开发是3D打印的关键一步。在这项研究中,制备了由镁和钠掺杂的碳化羟基磷灰石、β-磷酸三钙和Pluronic F-127组成的不同墨水来设计仿生骨支架。为了获得合适的可打印性,以及随后具有高形状保真度和适当机械性能的结构,所选择的组合物通过流变分析和力学测试进行了评估。结果表明,制备的油墨表现出剪切变薄的行为,并且通过增加Pluronic和双相磷酸钙(BCP)的浓度,可以获得更一致的凝胶,能够在印刷后保持其形状。支架的抗压强度在~ 8-60 MPa范围内变化。在扫描电镜图像中,烧结支架的形态也表现出宏观和微观的双重结构,这可以促进蛋白质的粘附和细胞行为。我们的研究结果表明,生物激发BCP支架可以以相对较高的精度用于松质骨替代品。
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引用次数: 0
Directed Energy Deposition of Parts with Internal Channels Using Removable Graphite Supports 使用可移动石墨支撑的内部通道零件的定向能量沉积
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-13 DOI: 10.1089/3dp.2023.0057
Dilara Celik, Ali Karaca, Bahattin Koc
Additive manufacturing (AM) techniques have the potential to produce complex parts, and many of these techniques require the use of support structures to prevent deformations and to minimize thermal effects during the printing process, particularly when building overhangs and internal cavities. However, removing the support structures through postprocessing incurs additional costs and time penalties. Unlike other AM techniques, support structures are not used in directed energy deposition (DED) technique due to its working principle. Therefore, special multiaxis complex path-planning strategies for DED are adopted to print relatively simple overhang geometries. Nevertheless, printing internal channels using this technique can still be challenging or nearly impossible. In this work, a novel DED process using graphite as a support material is proposed for additively manufacturing simple and complex internal channels. The support material is easily removed without requiring extensive machining processes. The results demonstrated that the support material did not negatively impact part quality, and in fact, the presence of different carbides at the interaction zone increased hardness and Young's modulus. Moreover, there were no cracks and or porosity at the support material-part interface. This study is the first of its kind to demonstrate the potential for using graphite as a support material for DED processes in additively manufacturing parts with complex internal channels and overhangs and highlights the need for further research in this area.
增材制造(AM)技术具有生产复杂零件的潜力,其中许多技术需要使用支撑结构来防止变形,并在打印过程中最大限度地减少热效应,特别是在构建悬空和内部腔时。但是,通过后处理去除支撑结构会产生额外的成本和时间损失。与其他增材制造技术不同,由于定向能沉积(DED)技术的工作原理,它不使用支撑结构。因此,采用特殊的多轴复杂路径规划策略来打印相对简单的悬垂几何形状。然而,使用这种技术打印内部通道仍然具有挑战性或几乎不可能。在这项工作中,提出了一种使用石墨作为支撑材料的新型DED工艺,用于增材制造简单和复杂的内部通道。支撑材料很容易拆卸,不需要大量的加工过程。结果表明,支撑材料对零件质量没有负面影响,实际上,在相互作用区不同碳化物的存在增加了硬度和杨氏模量。在支撑材料与部件的界面处没有出现裂纹和孔隙。这项研究首次展示了在具有复杂内部通道和悬空的增材制造零件中使用石墨作为DED工艺支撑材料的潜力,并强调了在该领域进一步研究的必要性。
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引用次数: 0
Fast Multifrequency Phase Unwrapping Method Based on 3D Printing Object Appearance Acquisition 基于3D打印物体外观获取的快速多频相位展开方法
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-11 DOI: 10.1089/3dp.2023.0166
Xiaomei Zheng, Yongqing Wang, Guohong Du, Shaoshuai Yin
3D printing is an indispensable technology in modern life and is widely used in aerospace, exoskeleton, and architecture. The increasing accuracy requirements of 3D printed objects in these fields require high-precision measurement methods to obtain accurate data. Based on the precision measurement requirements, in this study, a fast multifrequency phase unwrapping method based on 3D printing object appearance acquisition is proposed. By performing standard image acquisition of 3D printed objects that are not limited to materials and sampling locations, the surface shape and texture details of the objects can be accurately reconstructed using this method, independent of ambient light, with high robustness. Compared with the conventional multifrequency method, the required projection pattern is reduced from 12 to 9 and the overall measurement efficiency is improved by 25%, while maintaining the advantages of the independent pixel calculation method of the multifrequency method. In addition, the effectiveness of the method is experimentally verified by complex surface reconstruction experiments and plaster model experiments, which provide accurate measurement accuracy with high efficiency and precision. Therefore, the method can provide accurate measurements for 3D printed objects.
3D打印是现代生活中不可或缺的技术,广泛应用于航空航天、外骨骼和建筑领域。这些领域对3D打印对象的精度要求越来越高,需要高精度的测量方法来获得准确的数据。基于精度测量要求,本研究提出了一种基于3D打印物体外观采集的快速多频相位展开方法。通过对3D打印物体进行不受材料和采样位置限制的标准图像采集,该方法可以独立于环境光,准确地重建物体的表面形状和纹理细节,具有较高的鲁棒性。与传统的多频方法相比,所需的投影模式从12个减少到9个,整体测量效率提高了25%,同时保持了多频方法独立像素计算方法的优点。此外,通过复杂表面重建实验和石膏模型实验验证了该方法的有效性,提供了准确的测量精度,具有较高的效率和精度。因此,该方法可以为3D打印对象提供精确的测量。
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引用次数: 0
Additive Manufacturability and Parametric Studies on an Extended Three-Dimensional Re-Entrant Auxetic Structure with Angled Struts 带角杆的扩展三维可进补结构的增材制造性及参数化研究
4区 工程技术 Q3 ENGINEERING, MANUFACTURING Pub Date : 2023-10-10 DOI: 10.1089/3dp.2023.0086
Suian Wang, Chuang Deng, Olanrewaju Ojo, Bamidele Akinrinlola, Jared Kozub, Nan Wu
Auxetic honeycomb structures have been applied in lightweight sandwich structure and impact energy absorption applications due to their unique deformation performance. Based on the traditional two-dimensional reentrant honeycomb structure, a modified three-dimensional (3D) reentrant lattice structure with negative Poisson's ratio (NPR) is proposed. The studies on fabrication and design parameters are conducted, leading to a new understanding of the effects of these parameters on the printing quality and mechanical properties of such lattice structure with reentrant diagonal struts. Additive manufacturing (AM), specifically laser powder bed fusion, is used to fabricate five groups of 18Ni350 Maraging Steel samples with different geometric and printing parameters. The compression test is conducted to obtain the effects of NPR on the quasi-static stress-strain relationship of the proposed structure. The results show that smaller hatch distance and scan speed for 3D printing process can lead to less porosity level and more complete printing, resulting in larger stiffness and yield strength of the structure. The preferred AM process variables to improve structural quality with thin angled struts (diameter ≤0.5 mm) are presented. Moreover, with the help of the tuned finite element model based on experimental results, parametric analysis is conducted to confirm the effect of design parameters, including reentrant angle, strut cross-section shape, and size, on the compressive properties of the structure.
增塑型蜂窝结构以其独特的变形性能在轻质夹层结构和冲击吸能等领域得到了广泛的应用。在传统二维可重入蜂窝结构的基础上,提出了一种改进的负泊松比三维可重入晶格结构。通过对制作参数和设计参数的研究,对这些参数对这种可重入斜杆晶格结构的打印质量和力学性能的影响有了新的认识。采用增材制造技术(AM),特别是激光粉末床熔融技术,制备了5组具有不同几何参数和打印参数的18Ni350马氏体时效钢样品。通过压缩试验获得了NPR对结构准静态应力-应变关系的影响。结果表明,在3D打印过程中,越小的舱口距离和扫描速度,孔隙度越低,打印越完整,结构的刚度和屈服强度越大。提出了提高薄斜支板(直径≤0.5 mm)结构质量的首选增材制造工艺变量。在此基础上,利用基于实验结果的优化有限元模型,进行参数化分析,确定设计参数(入角、支撑截面形状、尺寸等)对结构抗压性能的影响。
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引用次数: 0
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3D Printing and Additive Manufacturing
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