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A Comparative Study of Picosecond Fractional 1064-nm Nd:YAG Laser Versus Fractional 10,600-nm Carbon Dioxide Laser in the Treatment of Abdominal Striae Alba: A Randomized, Prospective, Assessor-blinded, Split-abdomen Trial. 皮秒分数1064 nm Nd:YAG激光与分数10600 nm二氧化碳激光治疗腹部白纹的比较研究:一项随机、前瞻性、评估者盲法的裂腹试验。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-04-24 DOI: 10.1080/14764172.2025.2497416
Sharmaine H Lozano, Zharlah Gulmatico-Flores, Ma Flordeliz Abad-Casintahan

Background: Striae distensae are common disfiguring atrophic dermal scars. Fractional lasers have been utilized to improve the appearance of this condition.

Objectives: To compare the efficacy and safety of picosecond fractional 1064-nm Nd:YAG (PS Nd:YAG) laser versus fractional 10,600-nm Carbon Dioxide (CO2) laser in treating abdominal striae alba (SA).

Methods: Thirty-two women with Fitzpatrick skin types III-V and abdominal SA participated in a split-abdomen study, receiving four sessions of fractional PS Nd:YAG and CO2 laser treatments on each side at four-week intervals. Striae texture, atrophy, clinical improvement, and satisfaction were assessed for each side at one and three months, with striae length and width compared pre- and post-treatment. Adverse reactions were noted at each visit.

Results: Abdomen treated with both lasers had significantly improved skin texture, atrophy and clinical improvements (assessed by physicians and patients) at both follow-ups (p < 0.05), with no difference between the two. Striae length and width did not change significantly (p = 0.203 and p = 0.558). Patients reported greater improvement on the CO2-treated side at 1 month, but not at the final follow-up. High satisfaction was noted for both lasers. Adverse reactions noted after both lasers include erythema, edema, crusting/scaling, pruritus, pain and post-inflammatory hyperpigmentation. The PS Nd:YAG laser was associated with greater pain (p < 0.05), but shorter healing time of 10.26 days.

Conclusion: Both fractional PS Nd:YAG and CO2 lasers were effective, well-tolerated and safe treatment options for SA.

背景:扩张纹是常见的萎缩性皮肤疤痕。分数激光已被用于改善这种情况的外观。目的:比较皮秒分数1064 nm Nd:YAG (PS Nd:YAG)激光与分数10600 nm CO2 (CO2)激光治疗腹部白纹(SA)的疗效和安全性。方法:32名患有Fitzpatrick皮肤III-V型和腹部SA的女性参加了一项裂腹研究,每隔四周在每侧接受4次PS Nd:YAG和CO2激光治疗。在1个月和3个月时评估每侧的条纹质地、萎缩、临床改善和满意度,并比较治疗前和治疗后的条纹长度和宽度。每次就诊时均记录不良反应。结果:两种激光治疗腹部的皮肤质地、萎缩和临床改善(医生和患者评估)在两次随访中均有显著改善(p < 0.05),两者之间无差异。纹长和纹宽变化不显著(p = 0.203和p = 0.558)。患者在1个月时报告二氧化碳治疗侧有较大改善,但在最后随访时没有。两种激光器的满意度都很高。两种激光治疗后的不良反应包括红斑、水肿、结痂/脱屑、瘙痒、疼痛和炎症后色素沉着。PS Nd:YAG激光治疗组疼痛加重(p < 0.05),但愈合时间较短(10.26 d)。结论:分数PS Nd:YAG和CO2激光均是治疗SA有效、耐受性好、安全的选择。
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引用次数: 0
Safety and efficacy of platelet-rich plasma in the treatment of periorbital skin photoaging. 富血小板血浆治疗眶周皮肤光老化的安全性和有效性。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-06-02 DOI: 10.1080/14764172.2025.2513380
Xin-Li, Lingling-Hu, Weimin-Song, Qian-Lu

Periorbital skin photoaging is a common cosmetic problem.Presently, conventional treatment methods cannot achieve satisfactory results. Periorbital skin aging may benefit from platelet-rich plasma (PRP) injection. However, there is little experimental evidence on the safety and efficacy of PRP in the treatment of periorbital skin photoaging. To examine the safety and efficacy of PRP injection in the treatment of periorbital skin photoaging, PRP was injected into the periorbital skin of 20 patients, and patient satisfaction was assessed at the first month (M1), the second month (M2), and the third month (M3) after treatment. Two experienced dermatologists independently evaluated the patient's skin before and after treatment according to internationally accepted guidelines. The objective indicators of skin hydration, melanin index, erythema index, skin brightness, transepidermal water loss (TEWL), skin elasticity, and skin thickness were measured. Some subjective indicators, including pigmentation around the eyes, suborbital wrinkles, and static crow's feet, were significantly improved. Some objective indicators, including skin brightness, skin thickness, and collagen strength, were also significantly improved. Eye bags and TEWL slightly improved, but the differences were not statistically significant. The overall patient satisfaction with the treatment was high, no serious complications were noted, and the recovery profile was favorable. PRP injection was safe and effective for the treatment of periorbital skin photoaging.

眶周皮肤光老化是一个常见的美容问题。目前,常规的治疗方法不能达到满意的效果。富血小板血浆(PRP)注射可能对眼眶周围皮肤老化有益。然而,关于PRP治疗眶周皮肤光老化的安全性和有效性的实验证据很少。为探讨PRP注射液治疗眶周皮肤光老化的安全性和有效性,对20例患者眼眶周皮肤注射PRP,并于治疗后第1个月(M1)、第2个月(M2)、第3个月(M3)评估患者满意度。两位经验丰富的皮肤科医生根据国际公认的指导方针独立评估患者治疗前后的皮肤。测量皮肤水合、黑色素指数、红斑指数、皮肤亮度、经皮失水(TEWL)、皮肤弹性、皮肤厚度等客观指标。一些主观指标,包括眼睛周围的色素沉着、眶下皱纹和静态鱼尾纹,都有了明显的改善。一些客观指标,包括皮肤亮度,皮肤厚度,胶原蛋白强度也有明显改善。眼袋和TEWL略有改善,但差异无统计学意义。患者对治疗总体满意度高,无严重并发症发生,恢复情况良好。PRP注射治疗眶周皮肤光老化安全有效。
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引用次数: 0
Correction. 修正。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-06-10 DOI: 10.1080/14764172.2025.2516750
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引用次数: 0
Mottled hyperpigmentation caused by mesotherapy: successful treatment with a picosecond 1064 nm Nd:YAG laser. 光疗引起的斑驳色素沉着:用皮秒1064 nm Nd:YAG激光成功治疗。
IF 1.3 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-05-08 DOI: 10.1080/14764172.2025.2503935
Zhaokang Zhou, Yiping Ge

Post-inflammatory hyperpigmentation represents an acquired pigmentation anomaly frequently observed as a common sequela following acute or chronic skin inflammation, which often poses a challenge for treatment. We report a patient who developed persistent, mottled pigmentary macules all over her face subsequent to mesotherapy treatment. The patient was treated with a picosecond 1064 nm Nd:YAG laser in a two-step procedure way combined with a large- spot size, low-fluence mode and a fractional mode. After two treatment sessions, considerable improvement in her pigmentary lesions was observed, with no exacerbation or other complications.

炎症后色素沉着是一种获得性色素沉着异常,通常是急性或慢性皮肤炎症后的常见后遗症,通常对治疗构成挑战。我们报告一个病人谁发展持久的,斑驳的色素斑在她的脸随后的化疗治疗。患者接受皮秒1064 nm Nd:YAG激光治疗,采用大光斑尺寸、低通量模式和分数模式相结合的两步治疗方法。经过两次治疗后,观察到她的色素病变明显改善,没有恶化或其他并发症。
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引用次数: 0
Correction. 修正。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-06-11 DOI: 10.1080/14764172.2025.2517474
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引用次数: 0
A novel image fusion approach for visual enhancement of facial vessels in surgical filler injections. 一种新的面部血管填充注射图像融合增强方法。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2025-01-01 Epub Date: 2025-05-30 DOI: 10.1080/14764172.2025.2508991
Jiuai Sun, Kai Liu, Kai Li, Zhonghang Wu

In the absence of visual perception of the subcutaneous blood vessels, the performance of facial filling procedures may result in serious complications, such as blindness, cerebral infarction, and potentially fatal outcomes. In order to improve the visibility of facial vessels to ensure the filler injection procedure safe, this paper reports an efficient physical-based image fusion approach that combines simultaneously captured visible and near-infrared (NIR) images to produce vessel-highlighted effects. The enhancement of vessels visibility involves applying a customized sharpening filter to the invisible NIR image prior to merging it with the color facial image. The quantitative and subjective assessments of the fusion images indicate that the suggested approach is capable of efficiently reproducing a clear representation of blood vessels and realistically preserving their color and structural texture. Therefore, this new approach may be utilized to improve the efficiency and accuracy in locating or marking facial blood vessels and enhance the injection safety and precision of surgical filler injections.

在对皮下血管缺乏视觉感知的情况下,面部填充手术可能会导致严重的并发症,如失明、脑梗死和潜在的致命后果。为了提高面部血管的可见性以确保填充剂注射过程的安全性,本文报道了一种有效的基于物理的图像融合方法,该方法将同时捕获的可见光和近红外(NIR)图像结合在一起,以产生血管突出效果。血管可见性的增强包括在将不可见的近红外图像与彩色面部图像合并之前,对其应用定制的锐化滤波器。对融合图像的定量和主观评价表明,该方法能够有效地再现血管的清晰表现,并真实地保留血管的颜色和结构纹理。因此,这种新方法可以提高面部血管定位或标记的效率和准确性,提高外科填充物注射的安全性和精度。
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引用次数: 0
Use of a fractional 1570-nm diode laser scanner for nonablative face and neck rejuvenation. 使用分数型1570纳米二极管激光扫描仪进行非烧蚀性面部和颈部年轻化。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2024-11-16 Epub Date: 2025-01-02 DOI: 10.1080/14764172.2024.2441702
Munir Somji, Tino Solomon

Background: The use of non-ablative fractionated lasers for skin rejuvenation has been proven to be effective in improving skin texture, and has become popular due to minimal wounding, significantly shorter recovery times and decreased adverse effects.

Objective: To retrospectively analyze improvement in skin texture in healthy women aged over 18 years with Fitzpatrick skin type II-IV.

Methods: Participants received 3 facial and/or neck treatments with the 1570-nm fractional scanning diode laser at one-month intervals. Three months after the last treatment session two blinded evaluators assessed skin improvement using before and after photos. Pain and patient satisfaction were recorded.

Results: Sixteen women with a mean age of 45.4 ± 4.1 years (range 35-50 years) and skin type II-IV were included in the analysis. All 16 participants received facial treatments and seven (43.8%) also received neck treatments. Three months follow-up evaluation showed that the majority of participants had at least a visible change in the treated areas. Mean pain score was low and decreased with each treatment session.

Conclusion: Skin treatment using fractional scanning 1570-nm diode laser improves skin laxity in women with skin types II-IV. Larger studies are warranted to further clarify the efficacy and safety of this modality.

背景:使用非烧蚀分割激光进行皮肤再生已被证明可以有效改善皮肤质地,并且由于最小的伤害,显着缩短恢复时间和减少不良反应而受到欢迎。目的:回顾性分析18岁以上Fitzpatrick II-IV型健康女性皮肤质地的改善情况。方法:受试者每隔一个月接受3次1570纳米分数扫描二极管激光面部和/或颈部治疗。最后一次治疗三个月后,两位盲法评估者使用治疗前后的照片评估皮肤改善情况。记录疼痛和患者满意度。结果:16例女性纳入分析,平均年龄45.4±4.1岁(35-50岁),皮肤类型II-IV。所有16名参与者都接受了面部治疗,7名(43.8%)也接受了颈部治疗。三个月的随访评估显示,大多数参与者在治疗区域至少有明显的变化。平均疼痛评分较低,且随每次治疗而降低。结论:分次扫描1570 nm二极管激光皮肤治疗可改善II-IV型女性皮肤松弛。需要更大规模的研究来进一步阐明这种方式的有效性和安全性。
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引用次数: 0
Skin necrosis after autologous fat grafting for augmentation rhinoplasty: a case report and review of the literature. 自体脂肪移植隆鼻术后皮肤坏死1例报告及文献复习。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2024-11-16 Epub Date: 2024-12-31 DOI: 10.1080/14764172.2024.2421013
Xiao Jiang, Hanchen Cao, Xingfeng He, Xinhui Zou, Haoran Mao, Lingzhi Tang, Jinqiang Lu

Background: Autologous fat transplantation has gained increasing attention in the field of cosmetic surgery. However, a series of complications can occur after fat transplantation.

Case presentation: A 24-year-old woman presented at our Hospital with nasal skin necrosis and ulceration. She had undergone autologous fat transplantation on the nose six days ago. Physical examination showed an abnormal skin range of approximately 5 × 2 cm on the left side of the nose. The initial diagnosis was "skin necrosis after autologous fat grafting for augmentation rhinoplasty." In addition to the conventional treatment, topical oxygen therapy (TOT) and platelet-rich fibrin (PRF) injection were applied to the nasal wounds area. After 16 days, the pale and dark areas of necrosis on nose were scabby, and the local skin conditions were significantly improved.

Conclusion: We treated a case of ischemic necrosis of the skin after autologous fat grafting for augmentation rhinoplasty. For this kind of local vascular embolism, we first proposed a comprehensive therapy of "biological + physical + drug." The therapeutic method achieved satisfactory results, providing a new strategy for the clinical treatment of vascular embolism.

背景:自体脂肪移植在美容外科领域受到越来越多的关注。然而,脂肪移植后会出现一系列并发症。病例介绍:一名24岁女性因鼻皮肤坏死和溃疡来我院就诊。她六天前做了鼻子自体脂肪移植手术。体格检查显示鼻左侧皮肤异常范围约5 × 2 cm。最初的诊断是“自体脂肪移植隆鼻术后皮肤坏死”。在常规治疗的基础上,应用局部氧疗(TOT)和富血小板纤维蛋白(PRF)注射于鼻创面。16 d后,鼻部苍白、深色坏死区结痂,局部皮肤状况明显改善。结论:我们治疗了一例自体脂肪移植隆鼻术后皮肤缺血性坏死。针对这种局部血管栓塞,我们首次提出了“生物+物理+药物”的综合治疗方案。该治疗方法取得了满意的效果,为临床治疗血管栓塞提供了新的策略。
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引用次数: 0
A case of resistant granuloma faciale successfully treated with ablative fractional carbon dioxide laser. 用二氧化碳激光烧蚀点阵成功治疗一例耐药性面部肉芽肿。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2024-11-16 Epub Date: 2024-10-29 DOI: 10.1080/14764172.2024.2421019
Amy Prideaux, Emma Hitchens, Kay Thomas, Hannah Wainman, Daniel Keith

Granuloma faciale is a benign and rare skin disease, which usually presents as well-defined red-purple asymptomatic plaques or nodules on the face but can also present extra-facially. It poses a significant therapeutic challenge, with varying degrees of success reported by a range of medical and surgical treatments. We describe a 41-year-old lady with biopsy-confirmed facial granuloma faciale, affecting her nose, cheeks, upper lip, and forehead, who had failed a variety of medical treatments, UVB phototherapy, and pulsed dye laser. She was successfully treated with ablative fractional CO2 laser, with a sustained response, without recurrence or complications maintained for 1 year.

面部肉芽肿是一种罕见的良性皮肤病,通常表现为面部界限清楚的红紫色无症状斑块或结节,也可表现为面部以外的症状。它给治疗带来了巨大的挑战,据报道,一系列药物和手术治疗都取得了不同程度的成功。我们描述了一位 41 岁的女士,她的面部肉芽肿经活检确诊,累及鼻子、脸颊、上唇和前额。她接受了二氧化碳点阵消融激光治疗,并取得了成功,治疗效果持续了一年,没有复发或并发症。
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引用次数: 0
A clinical study on the efficacy of high frequency therapy on nasolabial and periorbital wrinkles. 高频疗法对鼻唇和眶周皱纹疗效的临床研究。
IF 1.2 4区 医学 Q3 DERMATOLOGY Pub Date : 2024-11-16 Epub Date: 2024-11-14 DOI: 10.1080/14764172.2024.2427018
Ana Keila Ferreira Dos Santos, Cintia Cristina Santi Martignago, Ana Laura Martins de Andrade, Livia Assis, Rodrigo Sávio Pessoa, Danieldos Anjos Costa, Laurita Dos Santos, Carla Tim

The high-frequency generator is considered a collagen stimulator and skin revitalizer, however there are few studies exploring its effects in the field of rejuvenation and aesthetics. Thus, this study aimed to investigate the impact of high frequency generator therapy on facial aging. A total of 26 participants aged between 50 and 60 years were selected and received high frequency generator treatment for eight weeks. The evaluation was conducted using a combination of photographic records and assessment tools, including Rosenberg scale, perception and satisfaction with treatment evaluation, overall aesthetic improvement scale, and modified Fitzpatrick scale. The analysis conducted by the Global Aesthetic Improvement Scale yielded significant results. The Modified Fitzpatrick Wrinkle Scale showed that high frequency therapy led to statistically significant improvements in the appearance of nasolabial wrinkles (right T0: 1.48, T8: 0.87; left T0: 1.51, T8: 1.05) and periorbital wrinkles (right T0: 1.69, T8: 1.05; left T0: 1.71, T8: 1.08). In conclusion, high frequency generator therapy can be a highly effective tool for treating skin aging on the face, however, we recommend that future research includes control groups, and adopts objective measures to expand knowledge about the effects of high frequency.

高频发生器被认为是胶原蛋白刺激器和皮肤活化剂,但很少有研究探讨其在年轻化和美学领域的效果。因此,本研究旨在探讨高频发生器疗法对面部衰老的影响。研究共选取了 26 名年龄在 50 至 60 岁之间的参与者,他们接受了为期八周的高频发生器治疗。评估结合了照片记录和评估工具,包括罗森伯格量表、治疗感知和满意度评估、整体美学改善量表和改良菲茨帕特里克量表。整体美学改善量表的分析结果显示,治疗效果显著。改良菲茨帕特里克皱纹量表显示,高频治疗对鼻唇皱纹(右侧 T0:1.48,T8:0.87;左侧 T0:1.51,T8:1.05)和眶周皱纹(右侧 T0:1.69,T8:1.05;左侧 T0:1.71,T8:1.08)的改善具有统计学意义。总之,高频发生器疗法是治疗面部皮肤老化的一种非常有效的工具,但我们建议今后的研究应包括对照组,并采用客观的测量方法,以扩大对高频效果的了解。
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引用次数: 0
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Journal of Cosmetic and Laser Therapy
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