Journal of Cosmetic and Laser Therapy最新文献

Background: Ecchymoses occur due to various insults to the skin which generally heals spontaneously within 2-3 weeks, with restoration of normal skin color. However, the prominent skin discolouration is troublesome for patients, prompting them to seek remedies for quick resolution. We highlight the importance of using long pulsed NdYAG laser as a treatment modality to speed the resolution of ecchymoses from 14 days to 24-48 hr in skin-type V-VI with negligible side effects, as its potential use is not widely known. We report on the first successful case series using this laser in skin-type V-VI.

Objectives: To assess the efficacy of long-pulsed NdYAG laser in early resolution of ecchymoses.

Methods: Six adults with skin types IV-VI with at least one ecchymosis were enrolled in the study. Subjects received treatment with the vascular mode 1064 nm long-pulsed NdYAG laser; (ALMA-Q multifunctional Q-switched ALMA laser). The number of treatment sessions varied from one to two at 3-day intervals. Photographs were taken pre-treatment, at 72 h, and 5 days post-treatment.

Results: In all six subjects, accelerated resolution of the treated bruise was evident. Treated lesions showed an average improvement of 80% after 72 h of treatment. After one week of treatment, all treated bruises completely disappeared (100%). No adverse effects were noted in any of the patients with no pain during the treatment sessions.

Limitations: Small sample size.

Conclusion: Our findings show this laser is safe and effective for rapidly resolving ecchymoses, reducing patient downtime without experiencing color changes when treated promptly.

Both ablative fractional laser (AFL) and non-ablative fractional laser (NAFL) are gaining popularity in the treatment of atrophic acne scars. However, single NAFL may not be as effective as single AFL in clinical practice. This split-face and evaluator-blind study compared the efficacy and safety of multiple consecutive NAFL (1565 nm Er: glass laser) and a single AFL (10600 nm CO₂ laser) in the treatment of facial atrophic acne scars. 13 subjects with V, U and M-shape atrophic scars were treated with either NAFL group (once a month for 3 consecutive sessions of 1565 nm Er: glass laser) or AFL group (a single session of fractional CO₂ laser). We found that both AFL group and NAFL group showed decreased 4-point scale and ECCA scores for respective V, U, M types, but there was no statistically difference between the two groups. NAFL group showed lower pain score, less oozing and crusting, and shorter duration of the adverse effects as well. The average satisfaction score was higher in NAFL group, although there was no statistically significance. In conclusion, consecutive triple NAFL treatment could approach a single AFL treatment for atrophic acne scars, while NAFL treatment causes less pain and fewer adverse events.

An 11-year-old Chinese girl had bluish-gray hyperpigmented patches combined with two dark brown papules on her left face since birth, and she developed a hypopigmented patch within the bluish-gray patches after sun exposure at the age of eight. Her previous medical history suggested that the hypopigmented patch was sensitive to the treatment of tacrolimus ointment cream and 308-nm excimer laser, while the hyperpigmented patches were insensitive to the previous initial laser treatment. Based on the clinical manifestations and a positive result of Wood's lamp examination, she was diagnosed with nevus of Ota, congenital halo nevus, and vitiligo. Only three cases of the co-occurrence of nevus of Ota and vitiligo within one area have been reported to date, while this is the first case to present a concurrence of congenital halo nevus and vitiligo within the area of nevus of Ota in the literature.

Background: Low-level laser therapy (LLLT) at 675 nm, within the red light spectrum, has emerged as a noninvasive therapeutic option for various dermatological conditions, including aging-related skin changes, melasma, acne vulgaris, and striae distensae.

Aims: This review aims to elucidate the therapeutic potential of the 675 nm laser in dermatology by synthesizing existing research evidence and clinical outcomes.

Methods: A literature search was conducted on PubMed to include studies investigating the efficacy of the 675 nm laser in diverse dermatological conditions. Parameters such as treatment protocols, patient demographics, and outcome measures were analyzed to assess the laser's therapeutic associations. The literature search composed of clinical trials or review articles. Studies were additionally identified by searching reference lists of included articles. Only articles in English were utilized for this review.

Results: The 675 nm laser demonstrates efficacy in addressing aging-related skin changes, including facial rejuvenation and wrinkle reduction, with significant improvement observed in skin texture and collagen remodeling. Additionally, the laser exhibits promising outcomes in treating melasma and hyperpigmentation disorders, acne vulgaris, and striae distensae, offering selective damage to target tissues with minimal adverse effects.

Conclusions: The 675 nm laser presents a versatile and innovative therapeutic option in dermatology, offering noninvasive treatment modalities for various health and cosmetic concerns. Further research and clinical trials are warranted to optimize treatment protocols and fully elucidate its therapeutic potential in diverse patient populations.

Basal cell carcinoma (BCC) is the most prevalent skin cancer, belonging to a group of skin cancers, namely Non-melanoma skin cancers. The increasing annual incidence, cosmetic disfigurements, and high recurrence rates give prominence to the role of the treatment methods used. Although there are numerous treatment modalities, pulsed dye laser (PDL) has emerged as an effective treatment for basal cell carcinoma in recent years. In this review, we aimed to assess the efficacy of pulsed dye laser on basal cell carcinoma in previous studies.

Lip augmentation (LA) procedures can cause complications such as edema, erythema, and pain. Photobiomodulation therapy (PBMT) has been indicated as a promissory alternative therapy. We evaluated different PBMT protocols on the management of its complications. Sixty-one patients post-LA were divided into four groups: control; PBMT λ660 nm; PBMT λ808 nm; and PBMT λ660 and 808 nm simultaneously. A higher analgesia was observed in the PBMT λ660 nm group. Upper-lip edema only decreased in the PBMT λ808 nm. Erythema increased in the control, whereas the PBMT groups had smaller score variations. PBMT emitting 660 or 808 nm was efficient for the treatment of edema and erythema post-LA.

Hyperpigmentation is a common dermatological condition characterized by the darkening of patches of skin compared to the surrounding areas. It can occur in individuals of all skin types and ethnicities, and is caused by an overproduction or accumulation of melanin, the pigment responsible for the color of our skin, hair, and eyes. This comprehensive overview aims to delve into the various types, causes, risk factors, clinical manifestations, diagnosis, and treatment options for hyperpigmentation. Additionally, it explores the global and national prevalence of hyperpigmentation, its etiology, pathophysiology and diagnosis and treatment strategies. Furthermore, examines the formulations and dosage forms used to treat hyperpigmentation, including their side effects. It also discusses combination drugs and their associated side effects, as well as novel drug delivery systems and nanocarriers employed in the treatment of hyperpigmentation, providing insight into future prospects in this field.

Areolar Sebaceous Hyperplasia (ASH) consists of enlarged Montgomery tubercles, skin-colored papules in the peripheral border of the areola, formed by the openings of the ducts of Montgomery's glands. Treatment options are only briefly discussed in literature as it is mostly presented as asymptomatic or paucisymptomatic. However, this traditional standpoint does not take into consideration the psychological impact that it may have on the patient. We present a case of prominent Montgomery tubercles treated with CO2 laser with good response.

Filler injection-associated alopecia is a rare complication. To date, including our case, we have identified 17 reported cases of alopecia following filler injection. Although uncommon, this complication should not be overlooked, especially given the increasing popularity of cosmetic procedures and the potential for misuse by unqualified individuals. In our case, unilateral partial cicatricial alopecia developed in the temporoparietal region following hyaluronic acid (HA) filler injection into the temporal area. The patient presented one month after the procedure, with no signs of vascular occlusion. Topical minoxidil was prescribed, resulting in approximately 80% hair regrowth in the affected area.

The process of face aging is characterized by various signs, including nasolabial folds, sagging and hollowing, all of which worsen with age. In some subjects, this phenomenon is exacerbated by sun exposure, bad diet, genetic factor, pollution, etc. This remains a great concern as it impacts physiologically and psychologically on patient quality of life. The intradermal solution based on bio-fermentative HA is indicated for correction of skin damages including rhytidosis, photoaging and skin dehydration. The present clinical investigation was designed for obtaining further clinical safety and efficacy data for the SKIN R intradermal solution for the treatment of skin damages. The efficacy of the treatments was assessed by measuring the pH, assessment of sebometry, and hydrometry, Global Aesthetic Improvement Scale and Subject satisfaction. All 15 screened and enrolled subjects were treated with the investigational device at least once. All subjects who were assessed had a neck photo taken at visits 1 and 2. The subjects' judgment of appearance after treatment changed with time, however, by the termination of the study on Day 60, 33.3% of subjects still considered their appearance very much improved, and 46,6% still considered their appearance much improved. The assessment of "satisfaction with treatment" was very high by the majority of subjects. No major adverse event was recorded. In conclusion, SKIN R is safe and well-tolerated and is effective in the treatment of skin damage.