Journal of Cosmetic and Laser Therapy最新文献

Areolar Sebaceous Hyperplasia (ASH) consists of enlarged Montgomery tubercles, skin-colored papules in the peripheral border of the areola, formed by the openings of the ducts of Montgomery's glands. Treatment options are only briefly discussed in literature as it is mostly presented as asymptomatic or paucisymptomatic. However, this traditional standpoint does not take into consideration the psychological impact that it may have on the patient. We present a case of prominent Montgomery tubercles treated with CO2 laser with good response.

Filler injection-associated alopecia is a rare complication. To date, including our case, we have identified 17 reported cases of alopecia following filler injection. Although uncommon, this complication should not be overlooked, especially given the increasing popularity of cosmetic procedures and the potential for misuse by unqualified individuals. In our case, unilateral partial cicatricial alopecia developed in the temporoparietal region following hyaluronic acid (HA) filler injection into the temporal area. The patient presented one month after the procedure, with no signs of vascular occlusion. Topical minoxidil was prescribed, resulting in approximately 80% hair regrowth in the affected area.

The process of face aging is characterized by various signs, including nasolabial folds, sagging and hollowing, all of which worsen with age. In some subjects, this phenomenon is exacerbated by sun exposure, bad diet, genetic factor, pollution, etc. This remains a great concern as it impacts physiologically and psychologically on patient quality of life. The intradermal solution based on bio-fermentative HA is indicated for correction of skin damages including rhytidosis, photoaging and skin dehydration. The present clinical investigation was designed for obtaining further clinical safety and efficacy data for the SKIN R intradermal solution for the treatment of skin damages. The efficacy of the treatments was assessed by measuring the pH, assessment of sebometry, and hydrometry, Global Aesthetic Improvement Scale and Subject satisfaction. All 15 screened and enrolled subjects were treated with the investigational device at least once. All subjects who were assessed had a neck photo taken at visits 1 and 2. The subjects' judgment of appearance after treatment changed with time, however, by the termination of the study on Day 60, 33.3% of subjects still considered their appearance very much improved, and 46,6% still considered their appearance much improved. The assessment of "satisfaction with treatment" was very high by the majority of subjects. No major adverse event was recorded. In conclusion, SKIN R is safe and well-tolerated and is effective in the treatment of skin damage.

Acne keloidalis nuchae (AKN) is a scarring folliculitis characterized by papules, pustules, and tumor-like masses on the neck and scalp. Management varies with severity; mild cases respond to topical treatments, while severe cases may require systemic therapies or surgical interventions. We present two tumor-stage AKN cases successfully treated with electrosurgical excision and loop cautery, followed by secondary intention healing. In Case 1, a 38-year-old male with extensive keloidal plaques achieved significant improvement after electrosurgical excision. In Case 2, a 19-year-old male with recurrent pustules saw notable cosmetic and symptomatic relief from loop cautery. Both techniques proved effective and enhanced healing.

Body contouring procedures are defined as modification of the body's appearance through changes in size or shape. RF energy applied to a specific skin layer leads to either dermal remodeling or fat reduction. The multi-polar RF handpiece was used once a week for a treatment course of 3-8 sessions. The clinical evaluation of 40 patients showed no significant adverse and some degree of circumferential reduction with moderate positive correlation to BMI in 100% of patients. The blinded evaluation demonstrated a 35% improvement in "skin laxity grade" with an average rate of "moderate improvement." The in-vivo histopathological analysis showed no acute heat injury as well as power-related progressive increase of fibroblasts proliferation and neocollagenesis. The device represents an effective treatment for skin laxity with a 100% response rate and long-term safety profile.

Mohs micrographic surgery (MMS) is the gold standard treatment for skin cancers of the face, but scarring in these cosmetically sensitive areas remains a challenge, with no clear consensus on the most effective treatments. This study reviews the literature on therapies for specifically facial scars following Mohs surgery, emphasizing their mechanism of action and evidence of efficacy. Non-invasive options such as topical silicone and pressure therapy have shown benefits, while advanced techniques like dermabrasion, microneedling, or energy devices like the pulse-dye, CO2, Erbium, and Nd:YAG lasers, show promise in improving scar pliability and visibility. Intralesional injections of corticosteroids, botulinum toxin, and dermal fillers also have supportive data. Conversely, treatments like topical onion extract and vitamin E lack evidence of efficacy. Managing hypertrophic granulation tissue (HGT) also remains critical to reduce aberrant scarring from second-intention healing (SIH). To ensure optimal clinical outcomes, clinicians should remain updated on the wide range of scar therapies available, focusing on those with established biochemical mechanisms and evidence of efficacy.

Background: Striae distensae are common disfiguring atrophic dermal scars. Fractional lasers have been utilized to improve the appearance of this condition.

Objectives: To compare the efficacy and safety of picosecond fractional 1064-nm Nd:YAG (PS Nd:YAG) laser versus fractional 10,600-nm Carbon Dioxide (CO2) laser in treating abdominal striae alba (SA).

Methods: Thirty-two women with Fitzpatrick skin types III-V and abdominal SA participated in a split-abdomen study, receiving four sessions of fractional PS Nd:YAG and CO2 laser treatments on each side at four-week intervals. Striae texture, atrophy, clinical improvement, and satisfaction were assessed for each side at one and three months, with striae length and width compared pre- and post-treatment. Adverse reactions were noted at each visit.

Results: Abdomen treated with both lasers had significantly improved skin texture, atrophy and clinical improvements (assessed by physicians and patients) at both follow-ups (p < 0.05), with no difference between the two. Striae length and width did not change significantly (p = 0.203 and p = 0.558). Patients reported greater improvement on the CO2-treated side at 1 month, but not at the final follow-up. High satisfaction was noted for both lasers. Adverse reactions noted after both lasers include erythema, edema, crusting/scaling, pruritus, pain and post-inflammatory hyperpigmentation. The PS Nd:YAG laser was associated with greater pain (p < 0.05), but shorter healing time of 10.26 days.

Conclusion: Both fractional PS Nd:YAG and CO2 lasers were effective, well-tolerated and safe treatment options for SA.

Periorbital skin photoaging is a common cosmetic problem.Presently, conventional treatment methods cannot achieve satisfactory results. Periorbital skin aging may benefit from platelet-rich plasma (PRP) injection. However, there is little experimental evidence on the safety and efficacy of PRP in the treatment of periorbital skin photoaging. To examine the safety and efficacy of PRP injection in the treatment of periorbital skin photoaging, PRP was injected into the periorbital skin of 20 patients, and patient satisfaction was assessed at the first month (M1), the second month (M2), and the third month (M3) after treatment. Two experienced dermatologists independently evaluated the patient's skin before and after treatment according to internationally accepted guidelines. The objective indicators of skin hydration, melanin index, erythema index, skin brightness, transepidermal water loss (TEWL), skin elasticity, and skin thickness were measured. Some subjective indicators, including pigmentation around the eyes, suborbital wrinkles, and static crow's feet, were significantly improved. Some objective indicators, including skin brightness, skin thickness, and collagen strength, were also significantly improved. Eye bags and TEWL slightly improved, but the differences were not statistically significant. The overall patient satisfaction with the treatment was high, no serious complications were noted, and the recovery profile was favorable. PRP injection was safe and effective for the treatment of periorbital skin photoaging.

Post-inflammatory hyperpigmentation represents an acquired pigmentation anomaly frequently observed as a common sequela following acute or chronic skin inflammation, which often poses a challenge for treatment. We report a patient who developed persistent, mottled pigmentary macules all over her face subsequent to mesotherapy treatment. The patient was treated with a picosecond 1064 nm Nd:YAG laser in a two-step procedure way combined with a large- spot size, low-fluence mode and a fractional mode. After two treatment sessions, considerable improvement in her pigmentary lesions was observed, with no exacerbation or other complications.