Pub Date : 2021-11-17Epub Date: 2022-03-23DOI: 10.1080/14764172.2022.2055079
Thanaporn Puaratanaarunkon, Pravit Asawanonda
A picosecond-domain laser reportedly elicits positive treatment outcomes for acne scar and enlarged pores, but multiple sessions are often required. We sought to evaluate the efficacy of one-session fractional picosecond 1064-nm laser in treating atrophic acne scar and conspicuous pores. Fifty-nine acne scar patients with skin phototypes III and IV were treated with picosecond 1064-nm laser with microlens array (MLA) (8 mm spot, 0.8 J/cm2, 10 Hz) for one session. The efficacy of acne scar was evaluated by Antera® 3D CS, whereas facial pore counts and diameter were evaluated by VISIA-CR and dermoscopic images, respectively. All measurements were performed at baseline, weeks 1, 2, 4 and 6. Acne scar volume and facial pore counts showed a statistically significant reduction at 1 week and subsequent follow-up period when compared to baseline (weeks 1-6; P < .001). The volume of acne scars and the number of enlarge pores decreased by 22.03% and 15.13%, respectively. Of note, there was no significant change in diameter of facial pores. The adverse events, including erythema and folliculitis, were mild and short-lived. A single session of picosecond 1064-nm laser with MLA was safe and effective in improving atrophic acne scar and the number of enlarged pores.
{"title":"Efficacy of a one-session fractional picosecond 1064-nm laser for the treatment of atrophic acne scar and enlarged facial pores.","authors":"Thanaporn Puaratanaarunkon, Pravit Asawanonda","doi":"10.1080/14764172.2022.2055079","DOIUrl":"https://doi.org/10.1080/14764172.2022.2055079","url":null,"abstract":"<p><p>A picosecond-domain laser reportedly elicits positive treatment outcomes for acne scar and enlarged pores, but multiple sessions are often required. We sought to evaluate the efficacy of one-session fractional picosecond 1064-nm laser in treating atrophic acne scar and conspicuous pores. Fifty-nine acne scar patients with skin phototypes III and IV were treated with picosecond 1064-nm laser with microlens array (MLA) (8 mm spot, 0.8 J/cm<sup>2</sup>, 10 Hz) for one session. The efficacy of acne scar was evaluated by Antera® 3D CS, whereas facial pore counts and diameter were evaluated by VISIA-CR and dermoscopic images, respectively. All measurements were performed at baseline, weeks 1, 2, 4 and 6. Acne scar volume and facial pore counts showed a statistically significant reduction at 1 week and subsequent follow-up period when compared to baseline (weeks 1-6; <i>P</i> < .001). The volume of acne scars and the number of enlarge pores decreased by 22.03% and 15.13%, respectively. Of note, there was no significant change in diameter of facial pores. The adverse events, including erythema and folliculitis, were mild and short-lived. A single session of picosecond 1064-nm laser with MLA was safe and effective in improving atrophic acne scar and the number of enlarged pores.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"202-206"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40315798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17Epub Date: 2022-07-03DOI: 10.1080/14764172.2022.2075898
Nihal Altunisik, Dursun Turkmen, Serpil Sener
The skin disease of the pilosebaceous unit created by demodex mites is called demodicosis. Recently, it has been brought to the agenda that laser therapies can be effective in reducing the intensity of demodex parasite. With this study, we aimed to evaluate the effect of pro-yellow laser applied to the face on the intensity of demodex parasite. Twenty-five patients who had referred to the dermatology polyclinic with a complaint of rash on the face and who had been given proyellow laser therapy during the past year were included in the study. Average pre-laser therapy demodex number per cm2 was 3.9 ± 5.0, while average post-therapy demodex number per cm2 was 2.6 ± 4.9 (p = .117). The 577-nm pro-yellow laser caused a change in demodex density. We found that the number of demodex following laser therapy decreased in some patients, while it increased in some others.
{"title":"Evaluation of the effect of 577-nm pro-yellow laser on demodex intensity.","authors":"Nihal Altunisik, Dursun Turkmen, Serpil Sener","doi":"10.1080/14764172.2022.2075898","DOIUrl":"https://doi.org/10.1080/14764172.2022.2075898","url":null,"abstract":"<p><p>The skin disease of the pilosebaceous unit created by demodex mites is called demodicosis. Recently, it has been brought to the agenda that laser therapies can be effective in reducing the intensity of demodex parasite. With this study, we aimed to evaluate the effect of pro-yellow laser applied to the face on the intensity of demodex parasite. Twenty-five patients who had referred to the dermatology polyclinic with a complaint of rash on the face and who had been given proyellow laser therapy during the past year were included in the study. Average pre-laser therapy demodex number per cm<sup>2</sup> was 3.9 ± 5.0, while average post-therapy demodex number per cm<sup>2</sup> was 2.6 ± 4.9 (p = .117). The 577-nm pro-yellow laser caused a change in demodex density. We found that the number of demodex following laser therapy decreased in some patients, while it increased in some others.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"221-224"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40469412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2021.1990961
N. Ignatieva, O. Zakharkina, A. Kurkov, M. Molchanov, K. Mazayshvili
ABSTRACT This work was aimed at elaborating an experimental ex vivo endovenous laser ablation (EVLA) model and evaluating the possibility of using differential scanning calorimetry (DSC) to determine the degree of collagen denaturation of the venous tissue and optimize the laser treatment settings. The control (non-varicose) and varicose vein specimens were subjected to chemical, thermal and morphological analyses. Varicose vein fragments were irradiated with 1.56-μm and 0.97-μm lasers in conditions closely similar to those of the clinical EVLA procedure. The laser treated specimens were subjected to thermal and histological analyses. A noticeable difference in chemical composition and structure was detected between the control and varicose veins. Glycosaminoglycan content increased significantly in varicose vein (P = .02), elastin content decreased insignificantly (P = .26) while collagen content showed a slight, but not significant, increase (P = .14). Varicose vein demonstrated regional variability in wall thickness, some decrease in the amount of smooth muscle cells, thinning and loosening of collagen fibers and fibrosis. The critical laser radiation power was demonstrated simultaneously to cause complete denaturation of collagen (as indicated by the DSC data) and coagulation necrosis of all the three venous wall layers, total homogenization of the tissue and obliteration of vasa vasorum (as indicated by the histological analysis data). Lower laser radiation powers fail to produce these effects. Critical laser power provides the desired result of the thermal effect on the vein ex vivo, namely, tissue necrosis and vasa vasorum destruction. The complete degradation of the collagen recorded by DSC could be a marker of the irreversible destruction of the vein wall in modeling of endoluminal thermal treatment.
{"title":"Analysis of the vein wall destruction under endovenous laser ablation in an ex vivo model","authors":"N. Ignatieva, O. Zakharkina, A. Kurkov, M. Molchanov, K. Mazayshvili","doi":"10.1080/14764172.2021.1990961","DOIUrl":"https://doi.org/10.1080/14764172.2021.1990961","url":null,"abstract":"ABSTRACT This work was aimed at elaborating an experimental ex vivo endovenous laser ablation (EVLA) model and evaluating the possibility of using differential scanning calorimetry (DSC) to determine the degree of collagen denaturation of the venous tissue and optimize the laser treatment settings. The control (non-varicose) and varicose vein specimens were subjected to chemical, thermal and morphological analyses. Varicose vein fragments were irradiated with 1.56-μm and 0.97-μm lasers in conditions closely similar to those of the clinical EVLA procedure. The laser treated specimens were subjected to thermal and histological analyses. A noticeable difference in chemical composition and structure was detected between the control and varicose veins. Glycosaminoglycan content increased significantly in varicose vein (P = .02), elastin content decreased insignificantly (P = .26) while collagen content showed a slight, but not significant, increase (P = .14). Varicose vein demonstrated regional variability in wall thickness, some decrease in the amount of smooth muscle cells, thinning and loosening of collagen fibers and fibrosis. The critical laser radiation power was demonstrated simultaneously to cause complete denaturation of collagen (as indicated by the DSC data) and coagulation necrosis of all the three venous wall layers, total homogenization of the tissue and obliteration of vasa vasorum (as indicated by the histological analysis data). Lower laser radiation powers fail to produce these effects. Critical laser power provides the desired result of the thermal effect on the vein ex vivo, namely, tissue necrosis and vasa vasorum destruction. The complete degradation of the collagen recorded by DSC could be a marker of the irreversible destruction of the vein wall in modeling of endoluminal thermal treatment.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"199 1","pages":"163 - 169"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74977589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2022.2052901
Bin Wang, Xianglin Mei, Yanlong Wang, Xin Hu, Fuqiu Li
ABSTRACT Noninvasive pulsed dye laser is the current gold standard for the treatment of port wine stains. However, most port wine stains are not completely cleared after pulsed dye laser therapy, owing to insufficient photocoagulation and laser-induced vascular regeneration and reperfusion. Several studies have explored approaches designed to improve treatment efficacy. This integrative literature review summarizes the results of clinical and animal studies published between 2004 and 2021. Pulsed dye laser has been administered in combination with photoelectric devices (the neodymium: yttrium-aluminum-garnet lasers, dual-wavelength 1064-/595-nm laser irradiation, fiberoptic Nd-YAG laser, photodynamic therapy, and radio frequency), and drugs (rapamycin, imiquimod, timolol, axitinib, endothelin receptor antagonist, artificial red blood cells and oxymetazoline). The initial results suggest that combination therapy is a direction worth exploring in the future. Further large prospective, blinded and controlled multicenter clinical trials with longer follow‐up period are required to obtain more robust evidence.
{"title":"Adjuncts to pulsed dye laser for treatment of port wine stains: a literature review","authors":"Bin Wang, Xianglin Mei, Yanlong Wang, Xin Hu, Fuqiu Li","doi":"10.1080/14764172.2022.2052901","DOIUrl":"https://doi.org/10.1080/14764172.2022.2052901","url":null,"abstract":"ABSTRACT Noninvasive pulsed dye laser is the current gold standard for the treatment of port wine stains. However, most port wine stains are not completely cleared after pulsed dye laser therapy, owing to insufficient photocoagulation and laser-induced vascular regeneration and reperfusion. Several studies have explored approaches designed to improve treatment efficacy. This integrative literature review summarizes the results of clinical and animal studies published between 2004 and 2021. Pulsed dye laser has been administered in combination with photoelectric devices (the neodymium: yttrium-aluminum-garnet lasers, dual-wavelength 1064-/595-nm laser irradiation, fiberoptic Nd-YAG laser, photodynamic therapy, and radio frequency), and drugs (rapamycin, imiquimod, timolol, axitinib, endothelin receptor antagonist, artificial red blood cells and oxymetazoline). The initial results suggest that combination therapy is a direction worth exploring in the future. Further large prospective, blinded and controlled multicenter clinical trials with longer follow‐up period are required to obtain more robust evidence.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"69 1","pages":"209 - 217"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79148359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2022.2048671
Dong Hye Lee, Ye-Jin Suh, Dong Hyun Kim, Sang Jun Lee, M. Shin
ABSTRACT Radiofrequency (RF) has been widely used as a noninvasive technique for skin tightening and rejuvenation. Moiré is a type of interference pattern corresponding to the shape of the face. We aimed to objectively evaluate the effect of RF on facial skin laxity using moiré. Ten subjects participated and were treated with a monopolar RF on the face. Clinical photographs and moiré images were obtained at the baseline and after treatment. The periorbital angle from the upper third of the face, zygomatic length ratio (L1/L2), angle from the middle third, perioral perpendicular length, and angle from the lower third were analyzed. After one session of RF treatment, the mean zygomatic length ratio (L1/L2) from the middle third of the face significantly increased in the 4th week (by 49.68%, P = .047). The L1/L2 ratio increased to nearly one, which were not significant after 8 weeks. The mean perioral perpendicular length decreased to 282.25 ± 84.069 pixels (px) after 4 weeks, and to 281.38 ± 76.03 px after 24 weeks; these differences were statistically significant. The parameters of zygomatic length ratio and perioral perpendicular length extracted from illuminated moiré images can be useful for objectively assessing various facial tightening treatments in clinical settings.
{"title":"Objective assessment of facial laxity changes after monopolar radiofrequency treatment by using moiré topography","authors":"Dong Hye Lee, Ye-Jin Suh, Dong Hyun Kim, Sang Jun Lee, M. Shin","doi":"10.1080/14764172.2022.2048671","DOIUrl":"https://doi.org/10.1080/14764172.2022.2048671","url":null,"abstract":"ABSTRACT Radiofrequency (RF) has been widely used as a noninvasive technique for skin tightening and rejuvenation. Moiré is a type of interference pattern corresponding to the shape of the face. We aimed to objectively evaluate the effect of RF on facial skin laxity using moiré. Ten subjects participated and were treated with a monopolar RF on the face. Clinical photographs and moiré images were obtained at the baseline and after treatment. The periorbital angle from the upper third of the face, zygomatic length ratio (L1/L2), angle from the middle third, perioral perpendicular length, and angle from the lower third were analyzed. After one session of RF treatment, the mean zygomatic length ratio (L1/L2) from the middle third of the face significantly increased in the 4th week (by 49.68%, P = .047). The L1/L2 ratio increased to nearly one, which were not significant after 8 weeks. The mean perioral perpendicular length decreased to 282.25 ± 84.069 pixels (px) after 4 weeks, and to 281.38 ± 76.03 px after 24 weeks; these differences were statistically significant. The parameters of zygomatic length ratio and perioral perpendicular length extracted from illuminated moiré images can be useful for objectively assessing various facial tightening treatments in clinical settings.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"27 1","pages":"170 - 175"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80182270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2022.2048673
Z. Mao, B. Lin, Yi-Dan Huang, Danping Huang
ABSTRACT Surgical treatment of eyelid margin lesions is challenging, and few studies focused on laser therapy of such type of lesions. To evaluate the safety and effectiveness of ultrapulse CO2 laser treatment under a microscope for benign eyelid margin lesions, we performed microscopic ultrapulse CO2 laser treatment win 132 patients with benign eyelid margin lesions for cosmetic reasons. Measurements included cosmetic results, complications and patients’ satisfaction. Eighty lesions involved the gray line and 24 lesions were in the lacrimal region. All patients achieved satisfactory cosmetic and therapeutic outcomes. Eyelid contour recovered well with no scar and no malposition. No secondary epiphora was noted after the lesions adjacent to the lacrimal punctum were removed. At the end of follow-up, only 2 patients had mild hypopigmentation and only 1 patient required repeat laser therapy for recurrence. It turned out that ultrapulse CO2 laser treatment under a microscope is a dependable, safe, and effective method for the treatment of benign eyelid margin lesions. It is an excellent alternative to traditional surgery, especially for lesions involving the gray line or positioned in proximity to the lacrimal punctum. It is beneficial for simplifying the treatment, improving the cosmetic result, and maintaining eyelid function.
{"title":"Microscopic treatment of benign eyelid margin lesions with ultrapulse carbon dioxide (CO2) laser","authors":"Z. Mao, B. Lin, Yi-Dan Huang, Danping Huang","doi":"10.1080/14764172.2022.2048673","DOIUrl":"https://doi.org/10.1080/14764172.2022.2048673","url":null,"abstract":"ABSTRACT Surgical treatment of eyelid margin lesions is challenging, and few studies focused on laser therapy of such type of lesions. To evaluate the safety and effectiveness of ultrapulse CO2 laser treatment under a microscope for benign eyelid margin lesions, we performed microscopic ultrapulse CO2 laser treatment win 132 patients with benign eyelid margin lesions for cosmetic reasons. Measurements included cosmetic results, complications and patients’ satisfaction. Eighty lesions involved the gray line and 24 lesions were in the lacrimal region. All patients achieved satisfactory cosmetic and therapeutic outcomes. Eyelid contour recovered well with no scar and no malposition. No secondary epiphora was noted after the lesions adjacent to the lacrimal punctum were removed. At the end of follow-up, only 2 patients had mild hypopigmentation and only 1 patient required repeat laser therapy for recurrence. It turned out that ultrapulse CO2 laser treatment under a microscope is a dependable, safe, and effective method for the treatment of benign eyelid margin lesions. It is an excellent alternative to traditional surgery, especially for lesions involving the gray line or positioned in proximity to the lacrimal punctum. It is beneficial for simplifying the treatment, improving the cosmetic result, and maintaining eyelid function.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"37 1","pages":"184 - 187"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81436212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2022.2049312
H. Johnson, Tiana Kazemi, R. Farah
ABSTRACT Objectives: The topical application of a combination Vitamin C, Vitamin E, and Ferulic acid serum following ablative fractional resurfacing has been reported to shorten post-procedure downtime and improve wound healing. However, transcutaneous drug delivery of cosmeceuticals initially meant for topical application have also been shown to have unintended side effects. The objective of our study was to report safety data from our single academic center experience consisting of patients treated with topical application of a vitamin C-containing cosmeceutical immediately following fractional ablative CO2 laser treatment with a focus on reportable side effects. Methods: A retrospective chart review of all patients at the University of Minnesota M Health Cosmetic Center who had fractional ablative CO2 (10,600 nm) laser procedure for any diagnosis followed by immediate one-time application of a combination serum containing 15% Vitamin C, 1% Vitamin E, and 0.5% Ferulic acid (C E Ferulic®, SkinCeuticals Inc., New York, NY) from Jan 1, 2015 to Dec 31, 2018 was performed. Pediatric and research opt-out patients were excluded. The medical records of these patients were manually reviewed for the following: age, sex, diagnosis, location, after-care instructions, antiviral and/or antibacterial prophylaxis use, and documentation of post-procedure side effects. Results: Thirty-three patients, encompassing a total of 45 treatment encounters, met inclusion criteria. There were ten cases of expected side effects: erythema (6), erythema with tenderness (1), erythema with mild bumpiness (1), skin peeling with pattern marking (1), and pain with slight bleeding (1). These were attributed to the normal post-procedure course and resolved without complications. There were no reported side effects related to the topical application of Vitamin C, Vitamin E, and Ferulic acid serum. Conclusions: The topical application of a Vitamin C, Vitamin E, and Ferulic acid serum immediately following fractional ablative CO2 laser therapy did not result in associated complications. However, these results may not be generalizable to longer application courses beyond the immediate post-procedure time period, nor to other cosmeceutical formulations. More studies examining the safety profile of topical cosmeceutical serums in laser-assisted drug delivery are needed.
【摘要】目的:据报道，局部应用复合维生素C、维生素E和阿魏酸血清，可缩短术后停机时间，改善伤口愈合。然而，经皮药妆的药物输送最初用于局部应用也已被证明有意想不到的副作用。我们研究的目的是报告我们单一学术中心经验的安全性数据，包括在分次烧蚀CO2激光治疗后立即局部应用含有维生素c的药妆治疗的患者，重点是可报告的副作用。方法:对2015年1月1日至2018年12月31日在明尼苏达大学M健康化妆品中心接受分次CO2消融(10,600 nm)激光手术的所有患者进行回顾性图表回顾，这些患者在任何诊断后立即一次性应用含有15%维生素C、1%维生素E和0.5%阿魏酸的联合血清(C E阿魏酸®，SkinCeuticals Inc.， New York, NY)。儿科和研究选择退出的患者被排除在外。对这些患者的医疗记录进行人工审查，包括以下内容:年龄、性别、诊断、地点、术后护理说明、抗病毒和/或抗菌预防药物的使用以及术后副作用的记录。结果:33例患者(共45次治疗)符合纳入标准。有10例预期的副作用:红斑(6例)，红斑伴压痛(1例)，红斑伴轻度隆起(1例)，皮肤脱皮伴图案标记(1例)，疼痛伴轻微出血(1例)。这些都归因于正常的术后过程，无并发症解决。局部应用维生素C、维生素E和阿魏酸血清没有副作用的报道。结论:局部应用维生素C，维生素E和阿魏酸血清后立即分次消融CO2激光治疗不会导致相关并发症。然而，这些结果可能不能推广到较长的应用程序，超出直接的术后时间周期，也不能推广到其他药妆配方。需要更多的研究来检查局部药妆血清在激光辅助给药中的安全性。
{"title":"Safety profile of laser-assisted drug delivery of vitamin C, E, and ferulic acid serum following ablative fractional resurfacing: A retrospective chart review","authors":"H. Johnson, Tiana Kazemi, R. Farah","doi":"10.1080/14764172.2022.2049312","DOIUrl":"https://doi.org/10.1080/14764172.2022.2049312","url":null,"abstract":"ABSTRACT Objectives: The topical application of a combination Vitamin C, Vitamin E, and Ferulic acid serum following ablative fractional resurfacing has been reported to shorten post-procedure downtime and improve wound healing. However, transcutaneous drug delivery of cosmeceuticals initially meant for topical application have also been shown to have unintended side effects. The objective of our study was to report safety data from our single academic center experience consisting of patients treated with topical application of a vitamin C-containing cosmeceutical immediately following fractional ablative CO2 laser treatment with a focus on reportable side effects. Methods: A retrospective chart review of all patients at the University of Minnesota M Health Cosmetic Center who had fractional ablative CO2 (10,600 nm) laser procedure for any diagnosis followed by immediate one-time application of a combination serum containing 15% Vitamin C, 1% Vitamin E, and 0.5% Ferulic acid (C E Ferulic®, SkinCeuticals Inc., New York, NY) from Jan 1, 2015 to Dec 31, 2018 was performed. Pediatric and research opt-out patients were excluded. The medical records of these patients were manually reviewed for the following: age, sex, diagnosis, location, after-care instructions, antiviral and/or antibacterial prophylaxis use, and documentation of post-procedure side effects. Results: Thirty-three patients, encompassing a total of 45 treatment encounters, met inclusion criteria. There were ten cases of expected side effects: erythema (6), erythema with tenderness (1), erythema with mild bumpiness (1), skin peeling with pattern marking (1), and pain with slight bleeding (1). These were attributed to the normal post-procedure course and resolved without complications. There were no reported side effects related to the topical application of Vitamin C, Vitamin E, and Ferulic acid serum. Conclusions: The topical application of a Vitamin C, Vitamin E, and Ferulic acid serum immediately following fractional ablative CO2 laser therapy did not result in associated complications. However, these results may not be generalizable to longer application courses beyond the immediate post-procedure time period, nor to other cosmeceutical formulations. More studies examining the safety profile of topical cosmeceutical serums in laser-assisted drug delivery are needed.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"20 1","pages":"207 - 208"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89344435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17DOI: 10.1080/14764172.2022.2055077
Li-Yi Chiu, Ya-Wei Lai, S. Hsu, Pei-Ling Chih, Po-Yen Lee
ABSTRACT To describe a case of picosecond laser-related corneal burn injury. Case presentation of a patient underwent picosecond laser cosmetic treatment, complicated with severe corneal burn injury. We evaluate patient’s visual acuity, corneal edema condition under slit lamp and corneal OCT (Optical coherence tomography), corneal shape with topography, and intraocular pressure. Picosecond laser emits optical pulses with duration between one to tens of picoseconds. The original purpose was to remove tattoos, but has now extended to a wide range of skin diseases and even cosmetic use. When applying cutaneous laser therapy, several ocular adverse events have been reported, mostly due to no appropriate ocular protection during treatment. We report a case of corneal burn injury after receiving picolaser therapy for a pigmented lesion over the upper lid. Severe cornea edema and vision impairment improved gradually after appropriate treatment. Even picosecond laser produce less thermal burns then other lasers, it is essential to use ocular protection during the entire treatment. According to our database search, this is the first picolaser-related ocular adverse event reported. Key Points Without appropriate protection, cosmetic laser treatments can cause severe ocular side effects and permanent visual impairment. We present this case to emphasize the importance of ocular protection during the entire treatment period, especially treatments of lesions over the eyelids. According to our knowledge and database search, this is the first reported ocular injury caused by picolaser.
{"title":"Corneal burn injury in picosecond laser treatment: A potential hazard in cosmetic therapy","authors":"Li-Yi Chiu, Ya-Wei Lai, S. Hsu, Pei-Ling Chih, Po-Yen Lee","doi":"10.1080/14764172.2022.2055077","DOIUrl":"https://doi.org/10.1080/14764172.2022.2055077","url":null,"abstract":"ABSTRACT To describe a case of picosecond laser-related corneal burn injury. Case presentation of a patient underwent picosecond laser cosmetic treatment, complicated with severe corneal burn injury. We evaluate patient’s visual acuity, corneal edema condition under slit lamp and corneal OCT (Optical coherence tomography), corneal shape with topography, and intraocular pressure. Picosecond laser emits optical pulses with duration between one to tens of picoseconds. The original purpose was to remove tattoos, but has now extended to a wide range of skin diseases and even cosmetic use. When applying cutaneous laser therapy, several ocular adverse events have been reported, mostly due to no appropriate ocular protection during treatment. We report a case of corneal burn injury after receiving picolaser therapy for a pigmented lesion over the upper lid. Severe cornea edema and vision impairment improved gradually after appropriate treatment. Even picosecond laser produce less thermal burns then other lasers, it is essential to use ocular protection during the entire treatment. According to our database search, this is the first picolaser-related ocular adverse event reported. Key Points Without appropriate protection, cosmetic laser treatments can cause severe ocular side effects and permanent visual impairment. We present this case to emphasize the importance of ocular protection during the entire treatment period, especially treatments of lesions over the eyelids. According to our knowledge and database search, this is the first reported ocular injury caused by picolaser.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"28 1","pages":"218 - 220"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83363760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-17Epub Date: 2022-03-22DOI: 10.1080/14764172.2022.2055076
María José Hombrados Balza, Jesús Rodríguez Lastra, Raquel Lic Arroyo Fernández
Localized fat and excess body fat: this is one of the main causes of dissatisfaction with body contour and decreased self-esteem. The objective of this report is to present the results of treatment using Capenergy C 200 in a group of young volunteers who received treatment only in the right half of the body. We will review the science and literature of the effect of TECAR and its role in body contouring. The average decrease in the arm is 2.9 cm p = .026. The nipple rise was 2.1 cm, p = .002. The decrease in abdominal diameter was 3.3 cm, p = .027 at the end of the treatment. For the thigh, the difference in diameter was 3.9 p = .026, this difference being statistically significant. TECAR radiofrequency treatment therapies, for body contouring in the breast, arms, abdomen and thighs, are effective and can show positive results after 6 treatment sessions, resulting in body satisfaction at the end of the treatment.
局部脂肪和多余的身体脂肪:这是对身体轮廓不满意和自尊心下降的主要原因之一。本报告的目的是介绍一组只接受右半身体治疗的年轻志愿者使用Capenergy C 200治疗的结果。我们将回顾有关TECAR效果及其在人体轮廓中的作用的科学和文献。上肢平均下降2.9 cm p = 0.026。乳头升高2.1 cm, p = 0.002。治疗结束时腹部直径减小3.3 cm, p = 0.027。大腿直径的差异为3.9 p = 0.026，差异有统计学意义。TECAR射频治疗治疗，在乳房，手臂，腹部和大腿的身体轮廓，是有效的，可以在6次治疗后显示出积极的结果，在治疗结束时导致身体满意。
{"title":"Improvement of body contour in young women using a high-power radiofrequency device.","authors":"María José Hombrados Balza, Jesús Rodríguez Lastra, Raquel Lic Arroyo Fernández","doi":"10.1080/14764172.2022.2055076","DOIUrl":"https://doi.org/10.1080/14764172.2022.2055076","url":null,"abstract":"<p><p>Localized fat and excess body fat: this is one of the main causes of dissatisfaction with body contour and decreased self-esteem. The objective of this report is to present the results of treatment using Capenergy C 200 in a group of young volunteers who received treatment only in the right half of the body. We will review the science and literature of the effect of TECAR and its role in body contouring. The average decrease in the arm is 2.9 cm p = .026. The nipple rise was 2.1 cm, p = .002. The decrease in abdominal diameter was 3.3 cm, p = .027 at the end of the treatment. For the thigh, the difference in diameter was 3.9 p = .026, this difference being statistically significant. TECAR radiofrequency treatment therapies, for body contouring in the breast, arms, abdomen and thighs, are effective and can show positive results after 6 treatment sessions, resulting in body satisfaction at the end of the treatment.</p>","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":" ","pages":"195-201"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40310582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Acne is one of the most common skin diseases whose disfiguring results may cause psychological problems. Despite of the various choices in the treatment of acne, new therapy with fewer complications and lower relapse rate is still in need. In this study, we aim to evaluate the clinical efficacy of a new therapy using selective sebaceous gland electro-thermolysis and non-thermal plasma (NTP) in refractory acne patients. Treatments were given at a monthly interval for three times. The last visit was set at 3 months after the third treatment. Thirty-six moderate to very severe acne patients were enrolled. All the patients got more than 50% clearance after the third treatment. The excellent response rate was 44% at 1 month after the third treatment and 50% at 3 months after the third treatment. Porphyrin and erythema values were significantly reduced after the third treatment. No irreversible complication was reported. Selective sebaceous gland electro-thermolysis combined with NTP can be a safe and effective new option in the treatment of acne.
{"title":"Treatment of refractory acne using selective sebaceous gland electro-thermolysis combined with non-thermal plasma","authors":"Xiaojin Wu, Yali Yang, Yutong Wang, Haoyu Wang, Ying Zheng, Jun Chen, Hui Xu","doi":"10.1080/14764172.2022.2050760","DOIUrl":"https://doi.org/10.1080/14764172.2022.2050760","url":null,"abstract":"ABSTRACT Acne is one of the most common skin diseases whose disfiguring results may cause psychological problems. Despite of the various choices in the treatment of acne, new therapy with fewer complications and lower relapse rate is still in need. In this study, we aim to evaluate the clinical efficacy of a new therapy using selective sebaceous gland electro-thermolysis and non-thermal plasma (NTP) in refractory acne patients. Treatments were given at a monthly interval for three times. The last visit was set at 3 months after the third treatment. Thirty-six moderate to very severe acne patients were enrolled. All the patients got more than 50% clearance after the third treatment. The excellent response rate was 44% at 1 month after the third treatment and 50% at 3 months after the third treatment. Porphyrin and erythema values were significantly reduced after the third treatment. No irreversible complication was reported. Selective sebaceous gland electro-thermolysis combined with NTP can be a safe and effective new option in the treatment of acne.","PeriodicalId":54852,"journal":{"name":"Journal of Cosmetic and Laser Therapy","volume":"39 1","pages":"188 - 194"},"PeriodicalIF":1.2,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78989183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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