Journal of Cosmetic and Laser Therapy最新文献

Laser-based procedures for tattoo removals are popular due to their high efficacy. However, multiple sessions are required to remove the tattoo satisfactorily. Various methods have been proposed to remove tattoos quickly. The objective of this study was to report nine patients who underwent tattoo removal using four different ways with a picosecond laser. The target site was divided into four areas, each of which received different tattoo removal protocols: picosecond laser alone, a modified R20 method, picosecond laser with MLA (microlens array) handpiece followed by picosecond laser, and picosecond laser after gel application. Clinical evaluations were conducted for all nine patients, focusing on clinical improvements such as tattoo fading and skin texture. The R20 method picosecond laser showed the most significant improvement in clinical evaluation. Histopathologic examination showed that the picosecond R20 treatment site had the least intradermal pigmentation. These case series provide further evidence to support the effectiveness of the R20 method of picosecond laser in histopathological examination and clinical improvement.

Androgenetic alopecia significantly affects individuals' quality of life, creating a need for better therapeutic strategies. Hair transplant surgery plays a key role in treating hair loss, with adjuncts like PRP and meso-cocktails explored to enhance results and procedure longevity. A prospective, single-blind study involved 112 males aged 25-50 years with Norwood-Hamilton grade IV-VI alopecia. Patients were randomly divided into two groups receiving different transplant methods. In Stage I, hair condition was evaluated, and QR678 Neo® was administered intradermally in Group A. Stage II involved hair transplantation surgery with diluted QR678 Neo® for graft preservation. Post-transplantation (Stage III) included additional QR678 Neo® administration in Group A. Evaluation methods consisted of global photographic assessment and videomicroscopy to measure hair growth and density. Group A (QR678 Neo®) demonstrated significant improvements in regrowth, density, and shaft diameter compared to Group B (conventional transplant). By Stage III, Group A had higher Global Photographic Assessment scores (8.87) and terminal hair count (181.02), with statistically significant differences (p < .001). The study suggests that QR678 Neo® improves outcomes and offers a promising treatment option for androgenetic alopecia.

Objective: The purpose of this study was to evaluate the effectiveness of 1565 nm NAFL treatment for atrophic acne scars using 22-MHz digital ultrasonography.

Methods: A total of 29 patients with acne atrophic scars were sequentially enrolled in this study. Digital clinical images of each patient's face were collected. The Quantitative Global Acne Scarring Grading System developed was employed to assess the outcomes of acne atrophic scars treated by 1565 nm NAFL. Two independent dermatologists performed an ultrasound examination of the acne atrophic scars using 22-MHz ultrasonography.

Results: Of all the patients received 1565 nm NAFL treatment, no adverse side effect was detected. The mean scores of Assessments Quantitative Global Acne Scarring Grading System in all the patients were no significant difference between the baseline and after 1-, 2-, and 3-month treatment. The means of epidermal thickness, dermal thickness, and epidermal echo intensity at the baseline and 1-, 2-, and 3-months were of no significant difference (P>0.05). The differences in the means of dermal echo intensity between the baseline and 1-, 2-, and 3- months were statistically significant (P<0.05).

Conclusion: 1565 nm NAFL was effective in improving the acne atrophic scars due to increased collagen fiber synthesis detected by 22 MHz frequency ultrasound system.

A uniform model for the treatment of aging signs of the face using Poly-L-lactic acid is presented. The causes of aging effects on the levels of the bone, the connective tissue, fat pads and the skin are addressed in a single procedure by use of needle or canula. For the treatment of the skin, a facial grid is introduced in order to spread the product evenly and avoid the formation of nodules. This standardized procedure provides a safer treatment protocol in order to avoid adverse events such as nodules or irregularities.

Delayed inflammatory nodules (DIN) after soft-tissue filler injection may occur after infections, vaccinations, or procedures. We report a DIN from predominantly low-molecular-weight HA (PLMW-HA) filler secondary to COVID-19 infection that was resistant to conservative management, requiring intralesional combination therapy with triamcinolone, 5-fluorouracil, and recombinant human hyaluronidase for resolution.

Introduction: There are established benefits of patient-selected music during conventional skin surgery, but a lack of evidence for laser procedures. Aims of this study were to assess whether patient-selected music during fractional ablative laser procedures enhances the patient experience, reduces perception of pain and anxiety, and impacts whether the patient would recommend the treatment to others and choose the treatment again.

Methods: Patients were 18 or over, receiving ablative fractional carbon dioxide laser treatment for any cause. Patients were offered to select the music played during their treatment and then asked to fill in a feedback questionnaire post treatment.

Results: A significant majority of 83.3% reported that the music enhanced their experience compared to previous treatments or compared to what they expected (25/30, p < .001). Music also significantly improved the likelihood that patients would recommend the treatment to others (n = 14, p < .05).

Conclusion: Music significantly enhances the experience of patients undergoing ablative fractional carbon dioxide laser resurfacing and increases the likelihood they will recommend the treatment to others. This appears to be independent of any perceived change in levels of pain or anxiety.

Background: Ecchymoses occur due to various insults to the skin which generally heals spontaneously within 2-3 weeks, with restoration of normal skin color. However, the prominent skin discolouration is troublesome for patients, prompting them to seek remedies for quick resolution. We highlight the importance of using long pulsed NdYAG laser as a treatment modality to speed the resolution of ecchymoses from 14 days to 24-48 hr in skin-type V-VI with negligible side effects, as its potential use is not widely known. We report on the first successful case series using this laser in skin-type V-VI.

Objectives: To assess the efficacy of long-pulsed NdYAG laser in early resolution of ecchymoses.

Methods: Six adults with skin types IV-VI with at least one ecchymosis were enrolled in the study. Subjects received treatment with the vascular mode 1064 nm long-pulsed NdYAG laser; (ALMA-Q multifunctional Q-switched ALMA laser). The number of treatment sessions varied from one to two at 3-day intervals. Photographs were taken pre-treatment, at 72 h, and 5 days post-treatment.

Results: In all six subjects, accelerated resolution of the treated bruise was evident. Treated lesions showed an average improvement of 80% after 72 h of treatment. After one week of treatment, all treated bruises completely disappeared (100%). No adverse effects were noted in any of the patients with no pain during the treatment sessions.

Limitations: Small sample size.

Conclusion: Our findings show this laser is safe and effective for rapidly resolving ecchymoses, reducing patient downtime without experiencing color changes when treated promptly.

Both ablative fractional laser (AFL) and non-ablative fractional laser (NAFL) are gaining popularity in the treatment of atrophic acne scars. However, single NAFL may not be as effective as single AFL in clinical practice. This split-face and evaluator-blind study compared the efficacy and safety of multiple consecutive NAFL (1565 nm Er: glass laser) and a single AFL (10600 nm CO₂ laser) in the treatment of facial atrophic acne scars. 13 subjects with V, U and M-shape atrophic scars were treated with either NAFL group (once a month for 3 consecutive sessions of 1565 nm Er: glass laser) or AFL group (a single session of fractional CO₂ laser). We found that both AFL group and NAFL group showed decreased 4-point scale and ECCA scores for respective V, U, M types, but there was no statistically difference between the two groups. NAFL group showed lower pain score, less oozing and crusting, and shorter duration of the adverse effects as well. The average satisfaction score was higher in NAFL group, although there was no statistically significance. In conclusion, consecutive triple NAFL treatment could approach a single AFL treatment for atrophic acne scars, while NAFL treatment causes less pain and fewer adverse events.

An 11-year-old Chinese girl had bluish-gray hyperpigmented patches combined with two dark brown papules on her left face since birth, and she developed a hypopigmented patch within the bluish-gray patches after sun exposure at the age of eight. Her previous medical history suggested that the hypopigmented patch was sensitive to the treatment of tacrolimus ointment cream and 308-nm excimer laser, while the hyperpigmented patches were insensitive to the previous initial laser treatment. Based on the clinical manifestations and a positive result of Wood's lamp examination, she was diagnosed with nevus of Ota, congenital halo nevus, and vitiligo. Only three cases of the co-occurrence of nevus of Ota and vitiligo within one area have been reported to date, while this is the first case to present a concurrence of congenital halo nevus and vitiligo within the area of nevus of Ota in the literature.

Background: Low-level laser therapy (LLLT) at 675 nm, within the red light spectrum, has emerged as a noninvasive therapeutic option for various dermatological conditions, including aging-related skin changes, melasma, acne vulgaris, and striae distensae.

Aims: This review aims to elucidate the therapeutic potential of the 675 nm laser in dermatology by synthesizing existing research evidence and clinical outcomes.

Methods: A literature search was conducted on PubMed to include studies investigating the efficacy of the 675 nm laser in diverse dermatological conditions. Parameters such as treatment protocols, patient demographics, and outcome measures were analyzed to assess the laser's therapeutic associations. The literature search composed of clinical trials or review articles. Studies were additionally identified by searching reference lists of included articles. Only articles in English were utilized for this review.

Results: The 675 nm laser demonstrates efficacy in addressing aging-related skin changes, including facial rejuvenation and wrinkle reduction, with significant improvement observed in skin texture and collagen remodeling. Additionally, the laser exhibits promising outcomes in treating melasma and hyperpigmentation disorders, acne vulgaris, and striae distensae, offering selective damage to target tissues with minimal adverse effects.

Conclusions: The 675 nm laser presents a versatile and innovative therapeutic option in dermatology, offering noninvasive treatment modalities for various health and cosmetic concerns. Further research and clinical trials are warranted to optimize treatment protocols and fully elucidate its therapeutic potential in diverse patient populations.