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Microscopic treatment of benign eyelid margin lesions with ultrapulse carbon dioxide (CO2) laser 超脉冲二氧化碳激光显微治疗良性眼睑边缘病变
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 DOI: 10.1080/14764172.2022.2048673
Z. Mao, B. Lin, Yi-Dan Huang, Danping Huang
ABSTRACT Surgical treatment of eyelid margin lesions is challenging, and few studies focused on laser therapy of such type of lesions. To evaluate the safety and effectiveness of ultrapulse CO2 laser treatment under a microscope for benign eyelid margin lesions, we performed microscopic ultrapulse CO2 laser treatment win 132 patients with benign eyelid margin lesions for cosmetic reasons. Measurements included cosmetic results, complications and patients’ satisfaction. Eighty lesions involved the gray line and 24 lesions were in the lacrimal region. All patients achieved satisfactory cosmetic and therapeutic outcomes. Eyelid contour recovered well with no scar and no malposition. No secondary epiphora was noted after the lesions adjacent to the lacrimal punctum were removed. At the end of follow-up, only 2 patients had mild hypopigmentation and only 1 patient required repeat laser therapy for recurrence. It turned out that ultrapulse CO2 laser treatment under a microscope is a dependable, safe, and effective method for the treatment of benign eyelid margin lesions. It is an excellent alternative to traditional surgery, especially for lesions involving the gray line or positioned in proximity to the lacrimal punctum. It is beneficial for simplifying the treatment, improving the cosmetic result, and maintaining eyelid function.
眼睑边缘病变的手术治疗具有挑战性,很少有研究关注激光治疗这类病变。为了评价超脉冲CO2激光在显微镜下治疗眼睑边缘良性病变的安全性和有效性,我们对132例因美观原因导致眼睑边缘良性病变的患者进行了超脉冲CO2激光显微治疗。测量包括美容效果、并发症和患者满意度。80个病变涉及灰线,24个病变位于泪区。所有患者均取得满意的美容和治疗效果。眼睑轮廓恢复良好,无瘢痕,无移位。泪点附近病变切除后未见继发性泪显。随访结束时,仅有2例患者出现轻度色素沉着,仅有1例患者复发需要重复激光治疗。结果表明,显微镜下超脉冲CO2激光治疗眼睑边缘良性病变是一种可靠、安全、有效的治疗方法。这是一个很好的替代传统手术,特别是病变涉及灰色线或定位在泪点附近。有利于简化治疗,改善美容效果,保持眼睑功能。
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引用次数: 0
Safety profile of laser-assisted drug delivery of vitamin C, E, and ferulic acid serum following ablative fractional resurfacing: A retrospective chart review 激光辅助给药维生素C, E和阿魏酸血清消融后的安全性:回顾性图表回顾
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 DOI: 10.1080/14764172.2022.2049312
H. Johnson, Tiana Kazemi, R. Farah
ABSTRACT Objectives: The topical application of a combination Vitamin C, Vitamin E, and Ferulic acid serum following ablative fractional resurfacing has been reported to shorten post-procedure downtime and improve wound healing. However, transcutaneous drug delivery of cosmeceuticals initially meant for topical application have also been shown to have unintended side effects. The objective of our study was to report safety data from our single academic center experience consisting of patients treated with topical application of a vitamin C-containing cosmeceutical immediately following fractional ablative CO2 laser treatment with a focus on reportable side effects. Methods: A retrospective chart review of all patients at the University of Minnesota M Health Cosmetic Center who had fractional ablative CO2 (10,600 nm) laser procedure for any diagnosis followed by immediate one-time application of a combination serum containing 15% Vitamin C, 1% Vitamin E, and 0.5% Ferulic acid (C E Ferulic®, SkinCeuticals Inc., New York, NY) from Jan 1, 2015 to Dec 31, 2018 was performed. Pediatric and research opt-out patients were excluded. The medical records of these patients were manually reviewed for the following: age, sex, diagnosis, location, after-care instructions, antiviral and/or antibacterial prophylaxis use, and documentation of post-procedure side effects. Results: Thirty-three patients, encompassing a total of 45 treatment encounters, met inclusion criteria. There were ten cases of expected side effects: erythema (6), erythema with tenderness (1), erythema with mild bumpiness (1), skin peeling with pattern marking (1), and pain with slight bleeding (1). These were attributed to the normal post-procedure course and resolved without complications. There were no reported side effects related to the topical application of Vitamin C, Vitamin E, and Ferulic acid serum. Conclusions: The topical application of a Vitamin C, Vitamin E, and Ferulic acid serum immediately following fractional ablative CO2 laser therapy did not result in associated complications. However, these results may not be generalizable to longer application courses beyond the immediate post-procedure time period, nor to other cosmeceutical formulations. More studies examining the safety profile of topical cosmeceutical serums in laser-assisted drug delivery are needed.
【摘要】目的:据报道,局部应用复合维生素C、维生素E和阿魏酸血清,可缩短术后停机时间,改善伤口愈合。然而,经皮药妆的药物输送最初用于局部应用也已被证明有意想不到的副作用。我们研究的目的是报告我们单一学术中心经验的安全性数据,包括在分次烧蚀CO2激光治疗后立即局部应用含有维生素c的药妆治疗的患者,重点是可报告的副作用。方法:对2015年1月1日至2018年12月31日在明尼苏达大学M健康化妆品中心接受分次CO2消融(10,600 nm)激光手术的所有患者进行回顾性图表回顾,这些患者在任何诊断后立即一次性应用含有15%维生素C、1%维生素E和0.5%阿魏酸的联合血清(C E阿魏酸®,SkinCeuticals Inc., New York, NY)。儿科和研究选择退出的患者被排除在外。对这些患者的医疗记录进行人工审查,包括以下内容:年龄、性别、诊断、地点、术后护理说明、抗病毒和/或抗菌预防药物的使用以及术后副作用的记录。结果:33例患者(共45次治疗)符合纳入标准。有10例预期的副作用:红斑(6例),红斑伴压痛(1例),红斑伴轻度隆起(1例),皮肤脱皮伴图案标记(1例),疼痛伴轻微出血(1例)。这些都归因于正常的术后过程,无并发症解决。局部应用维生素C、维生素E和阿魏酸血清没有副作用的报道。结论:局部应用维生素C,维生素E和阿魏酸血清后立即分次消融CO2激光治疗不会导致相关并发症。然而,这些结果可能不能推广到较长的应用程序,超出直接的术后时间周期,也不能推广到其他药妆配方。需要更多的研究来检查局部药妆血清在激光辅助给药中的安全性。
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引用次数: 3
Corneal burn injury in picosecond laser treatment: A potential hazard in cosmetic therapy 皮秒激光治疗角膜烧伤:美容治疗中的潜在危害
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 DOI: 10.1080/14764172.2022.2055077
Li-Yi Chiu, Ya-Wei Lai, S. Hsu, Pei-Ling Chih, Po-Yen Lee
ABSTRACT To describe a case of picosecond laser-related corneal burn injury. Case presentation of a patient underwent picosecond laser cosmetic treatment, complicated with severe corneal burn injury. We evaluate patient’s visual acuity, corneal edema condition under slit lamp and corneal OCT (Optical coherence tomography), corneal shape with topography, and intraocular pressure. Picosecond laser emits optical pulses with duration between one to tens of picoseconds. The original purpose was to remove tattoos, but has now extended to a wide range of skin diseases and even cosmetic use. When applying cutaneous laser therapy, several ocular adverse events have been reported, mostly due to no appropriate ocular protection during treatment. We report a case of corneal burn injury after receiving picolaser therapy for a pigmented lesion over the upper lid. Severe cornea edema and vision impairment improved gradually after appropriate treatment. Even picosecond laser produce less thermal burns then other lasers, it is essential to use ocular protection during the entire treatment. According to our database search, this is the first picolaser-related ocular adverse event reported. Key Points Without appropriate protection, cosmetic laser treatments can cause severe ocular side effects and permanent visual impairment. We present this case to emphasize the importance of ocular protection during the entire treatment period, especially treatments of lesions over the eyelids. According to our knowledge and database search, this is the first reported ocular injury caused by picolaser.
摘要:报告1例皮秒激光角膜烧伤。一例皮秒激光美容治疗并发严重角膜烧伤的病例报告。我们评估了患者的视力,裂隙灯和角膜OCT(光学相干断层扫描)下角膜水肿情况,角膜形状与地形图和眼压。皮秒激光器发射的光脉冲持续时间在一到几十皮秒之间。最初的目的是去除纹身,但现在已经扩展到广泛的皮肤病,甚至化妆品用途。当应用皮肤激光治疗时,一些眼部不良事件已被报道,主要是由于治疗期间没有适当的眼部保护。我们报告一例角膜烧伤后接受皮激光治疗色素病变在上眼睑。重度角膜水肿及视力损害经适当治疗后逐渐改善。即使皮秒激光比其他激光产生更少的热烧伤,在整个治疗过程中使用眼部保护是必不可少的。根据我们的数据库搜索,这是第一例与皮激光相关的眼部不良事件报道。如果没有适当的保护,激光美容治疗可能会导致严重的眼部副作用和永久性视力损害。我们提出这个病例,以强调在整个治疗期间眼部保护的重要性,特别是眼睑病变的治疗。根据我们的知识和数据库检索,这是首次报道由激光引起的眼部损伤。
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引用次数: 0
Improvement of body contour in young women using a high-power radiofrequency device. 使用高功率射频设备改善年轻女性的身体轮廓。
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 Epub Date: 2022-03-22 DOI: 10.1080/14764172.2022.2055076
María José Hombrados Balza, Jesús Rodríguez Lastra, Raquel Lic Arroyo Fernández

Localized fat and excess body fat: this is one of the main causes of dissatisfaction with body contour and decreased self-esteem. The objective of this report is to present the results of treatment using Capenergy C 200 in a group of young volunteers who received treatment only in the right half of the body. We will review the science and literature of the effect of TECAR and its role in body contouring. The average decrease in the arm is 2.9 cm p = .026. The nipple rise was 2.1 cm, p = .002. The decrease in abdominal diameter was 3.3 cm, p = .027 at the end of the treatment. For the thigh, the difference in diameter was 3.9 p = .026, this difference being statistically significant. TECAR radiofrequency treatment therapies, for body contouring in the breast, arms, abdomen and thighs, are effective and can show positive results after 6 treatment sessions, resulting in body satisfaction at the end of the treatment.

局部脂肪和多余的身体脂肪:这是对身体轮廓不满意和自尊心下降的主要原因之一。本报告的目的是介绍一组只接受右半身体治疗的年轻志愿者使用Capenergy C 200治疗的结果。我们将回顾有关TECAR效果及其在人体轮廓中的作用的科学和文献。上肢平均下降2.9 cm p = 0.026。乳头升高2.1 cm, p = 0.002。治疗结束时腹部直径减小3.3 cm, p = 0.027。大腿直径的差异为3.9 p = 0.026,差异有统计学意义。TECAR射频治疗治疗,在乳房,手臂,腹部和大腿的身体轮廓,是有效的,可以在6次治疗后显示出积极的结果,在治疗结束时导致身体满意。
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引用次数: 2
Treatment of refractory acne using selective sebaceous gland electro-thermolysis combined with non-thermal plasma 选择性皮脂腺电热溶解联合非热等离子体治疗难治性痤疮
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 DOI: 10.1080/14764172.2022.2050760
Xiaojin Wu, Yali Yang, Yutong Wang, Haoyu Wang, Ying Zheng, Jun Chen, Hui Xu
ABSTRACT Acne is one of the most common skin diseases whose disfiguring results may cause psychological problems. Despite of the various choices in the treatment of acne, new therapy with fewer complications and lower relapse rate is still in need. In this study, we aim to evaluate the clinical efficacy of a new therapy using selective sebaceous gland electro-thermolysis and non-thermal plasma (NTP) in refractory acne patients. Treatments were given at a monthly interval for three times. The last visit was set at 3 months after the third treatment. Thirty-six moderate to very severe acne patients were enrolled. All the patients got more than 50% clearance after the third treatment. The excellent response rate was 44% at 1 month after the third treatment and 50% at 3 months after the third treatment. Porphyrin and erythema values were significantly reduced after the third treatment. No irreversible complication was reported. Selective sebaceous gland electro-thermolysis combined with NTP can be a safe and effective new option in the treatment of acne.
痤疮是最常见的皮肤病之一,其毁容结果可引起心理问题。尽管痤疮的治疗方法多种多样,但仍需要并发症少、复发率低的新疗法。在这项研究中,我们旨在评估选择性皮脂腺电热溶解和非热等离子体(NTP)治疗难治性痤疮患者的临床疗效。治疗间隔为每月三次。最后一次访问是在第三次治疗后3个月。研究人员招募了36名中度至重度痤疮患者。第三次治疗后,所有患者的清除率均在50%以上。第三次治疗后1个月的优异有效率为44%,第三次治疗后3个月的优异有效率为50%。第三次治疗后,卟啉和红斑值明显降低。无不可逆并发症报道。选择性皮脂腺电热溶解结合NTP可以是一个安全有效的治疗痤疮的新选择。
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引用次数: 1
Clinical efficacy and safety of a focused-radiofrequency device on middle and lower face rejuvenation: a retrospective clinical study 聚焦射频装置用于中、下面部年轻化的临床疗效和安全性:回顾性临床研究
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-11-17 DOI: 10.1080/14764172.2022.2048672
Yiqiu Zhang, Min Yan, Jing Mi, Y. Zeng, Huyan Lin, M. Yao, Jiying Dong, Shen Wang
ABSTRACT The aim of the present study was to evaluate the efficacy and safety of a unipolar focused-RF device used to rejuvenate the middle and lower face and to create an assessment system. This retrospective study comprised 52 patients with mild-to-moderate skin laxity and wrinkles who received 1–3 treatments 1 month apart and were followed up for 1–7 months. At baseline and post-treatment, three blinded observers measured facial contour and lines, analyzed VISIA scores, and assessed the results using Alexiades Comprehensive Grading Scale (ACGS) and Global Aesthetic Improvement Scale (GAIS). Significant improvements were observed (P < .05) in facial width (left 5.95%, right 5.66%), nasolabial folds (left 18.98%, right 20.56%), marionette lines (left 18.88%, right 25.80%), and cheek lines (left 3.35%, right 3.05%) and in the scores of wrinkles (15.37%), texture (13.67%), pores (6.48%), and red areas (6.57%) using VISIA. There was an obvious reduction in wrinkles, laxity, erythema/telangiectasia based on ACGS, and 75% improved and 5.8% much improved using GAIS. There was no severe side effect. We suggest that the unipolar focused-RF device is an effective and safe technique for middle and lower face rejuvenation and provides a series of comprehensive assessment methods based on standardized photos using VISIA.
本研究的目的是评估单极聚焦射频设备用于中、下面部恢复活力的有效性和安全性,并建立一个评估系统。本回顾性研究纳入52例轻度至中度皮肤松弛和皱纹患者,每隔1个月接受1 - 3次治疗,随访1 - 7个月。在基线和治疗后,三名盲法观察者测量面部轮廓和线条,分析VISIA评分,并使用Alexiades综合评分量表(ACGS)和全球美学改善量表(GAIS)评估结果。在面部宽度(左5.95%,右5.66%)、鼻唇沟(左18.98%,右20.56%)、线线(左18.88%,右25.80%)、颊纹(左3.35%,右3.05%)以及皱纹(15.37%)、纹理(13.67%)、毛孔(6.48%)和红区(6.57%)评分方面,使用VISIA均有显著改善(P < 0.05)。在ACGS的基础上,皱纹、松弛、红斑/毛细血管扩张明显减少,75%的患者改善,5.8%的患者改善。没有严重的副作用。我们认为单极聚焦射频装置是一种安全有效的中下面部年轻化技术,并提供了一系列基于VISIA标准化照片的综合评估方法。
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引用次数: 0
Efficacy of a laser with a pulse duration of 300 ps in skin rejuvenation and treatment of pigmentation disorders in Asians: a series of four cases. 脉冲持续时间为300ps的激光在亚洲人皮肤年轻化和治疗色素沉着障碍方面的疗效:一系列四例。
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-08-01 Epub Date: 2021-12-29 DOI: 10.1080/14764172.2021.2016846
Jie Hoon Kim, Soo Eun Jung, Yun Hwa Park
ABSTRACT The photothermal effect of lasers is minimized and the photoacoustic effect is maximized as the pulse duration is shortened. Therefore, picosecond lasers with a short pulse and high peak power can be used to effectively treat various pigment disorders by reducing tissue damage. The first picosecond lasers were used for tattoo removal; they are also widely used for pigment treatment because of their reduced side effects compared with nanosecond lasers. Recently, picosecond lasers have been shown to be effective in the treatment of various skin conditions such as acne scars and large pores. There are many studies on picosecond lasers; however, there are no studies on a laser with a pulse duration of 300 ps. This report describes the use of a 300 ps Nd:YAG laser for treating pigment disorders and for skin rejuvenation in four Asians, with no side effects. Determining the clinical significance of the 300 ps pulse duration through comparative studies with various picosecond lasers is needed.
随着脉冲持续时间的缩短,激光的光热效应最小化,光声效应最大化。因此,具有短脉冲和高峰值功率的皮秒激光可以通过减少组织损伤来有效地治疗各种色素紊乱。皮秒激光首次用于去除纹身;与纳秒激光相比,它们的副作用更小,因此也被广泛用于色素治疗。最近,皮秒激光已被证明是有效的治疗各种皮肤状况,如痤疮疤痕和大毛孔。皮秒激光器的研究有很多;然而,目前还没有关于脉冲持续时间为300ps的激光的研究。本报告描述了在四个亚洲人身上使用300ps Nd:YAG激光治疗色素紊乱和皮肤年轻化,没有副作用。需要通过与各种皮秒激光器的比较研究来确定300ps脉冲持续时间的临床意义。
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引用次数: 1
A prospective study on the treatment of immediate post-operative scar with narrowband intense pulsed light under polarized dermoscopy. 偏光皮肤镜下窄带强脉冲光治疗术后即刻瘢痕的前瞻性研究。
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-08-01 Epub Date: 2022-01-17 DOI: 10.1080/14764172.2021.2016844
Qianya Su, Fei Wang, Yuanyuan Chai, Qiao Yan, Fengyuan Wang, Zhengbang Dong, Hai-Jing Yang

(a) To evaluate the efficacy and safety of narrow-band intense-pulsed light (DPL) in immediate post-operative scar. (b) To observe the process of scar formation under dermoscopy in the first 6 months. Nine patients with postoperative scars were enrolled in the randomized, prospective, split-scar study. Patients were treated in one half of the scar with DPL for cosmetic improvement at a wavelength of 500-600 nm and the other half was not treated as control. The laser treatments were initiated 2 weeks after the surgery and were given 3 times over a 4-week period. All patients were followed-up for 3 months from the last treatment. Photographs and dermoscopy digital images were collected each time. (a) Neither DPL or control produce statistically significant improvements in Vancouver Scar Scale. Moreover, comparatively, there was no statistical difference in Vancouver Scar Scale between DPL or control. However, 6 out of 9 patients treated with DPL had reduced scores in vascularity sooner compared with control. (b) Under dermoscopy, redness, and swelling were obvious from 2 weeks after surgery, but were gradually alleviated. The surface of the scar gradually became uneven and rough. DPL might be beneficial in early recovery of immediate post-operative scar.

(a)评价窄带强脉冲光(DPL)治疗术后即刻瘢痕的疗效和安全性。(b)观察前6个月皮肤镜下瘢痕形成过程。9例术后瘢痕患者被纳入随机、前瞻性、瘢痕分裂研究。患者在有DPL的一半疤痕处进行500-600 nm波长的治疗以改善外观,另一半不作为对照治疗。手术后2周开始激光治疗,4周内进行3次激光治疗。所有患者均自末次治疗后随访3个月。每次均收集照片和皮肤镜数码图像。(a) DPL和对照组在温哥华疤痕量表上都没有统计学上的显著改善。此外,DPL组与对照组的温哥华疤痕量表比较无统计学差异。然而,与对照组相比,接受DPL治疗的9名患者中有6名血管功能评分下降得更快。(b)术后2周皮肤镜下红肿明显,但逐渐缓解。疤痕的表面逐渐变得凹凸不平。DPL可能有利于术后瘢痕的早期恢复。
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引用次数: 0
Fractional microneedle radiofrequency device and fractional erbium-doped glass 1,565-nm device treatment of human facial photoaging: a prospective, split-face, random clinical trial. 分数微针射频装置和分数掺铒玻璃1565纳米装置治疗人类面部光老化:一项前瞻性,裂面,随机临床试验。
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-08-01 Epub Date: 2022-01-27 DOI: 10.1080/14764172.2022.2033783
Wenjie Dou, Qing Yang, Yue Yin, Xing Fan, Zhe Yang, Zhe Jian, Yanni Zhu, Jingyi Wei, Huan Jing, Xianjie Ma

Microneedle fractional radiofrequency (MFR) and non-ablative 1565 nm fractional laser (NAFL) have recently been introduced as new techniques to address the growing concern of facial photoaging. In this prospective randomized split-face study, we wanted to compare the safety and efficacy of MFR with that of NAFL for the treatment of facial photoaging in Asian patients. Fifteen healthy Chinese patients were enrolled for this randomized split-face study. Each patient underwent three sessions of treatment with MFR and NAFL on opposite sides of their face, one month apart. A blinded outcome assessment of the photoaging severity was performed by two independent plastic surgeons on a 5-point visual analogue scale (VAS, 0-4). Patient satisfaction was also scored based on a 5-point VAS (0 = dissatisfaction, 4 = extremely satisfied). Sagging of the nasolabial groove was evaluated using the Antera 3D camera, facial wrinkles and pores using the VISIA skin analysis system. Any adverse events that occurred during the study were also evaluated. Based on the VAS scores and results from the Antera 3D and VISIA, it was noted that there was a significant improvement in facial skin laxity, wrinkles, and pores, and lesser sagging of the nasolabial groove on both the MFR and NAFL sides of the face, compared with that of the baseline. Most patients were satisfied with the treatment and reported tolerable pain and crusting. Although no significant differences were observed between the MFR and NAFL treatments, the NAFL treatment resulted in a shorter downtime(4.56 ± 2.72d) than the MFR treatment(6.96 ± 3.27d). This study confirms the efficacy of MFR and NAFL treatments for facial skin rejuvenation in Asian patients. Furthermore, the therapies were found to be safe and well-tolerated. Our findings suggest that NAFL may be a more convenient treatment modality for facial photoaging because of its shorter downtime. However, sagging of the nasolabial groove was more improved by the MFR treatment than by the NAFL treatment.

微针分数射频(MFR)和非烧蚀1565nm分数激光(NAFL)是近年来被引入的新技术,以解决日益关注的面部光老化问题。在这项前瞻性随机裂脸研究中,我们希望比较MFR与NAFL治疗亚洲患者面部光老化的安全性和有效性。15名健康的中国患者参加了这项随机裂脸研究。每位患者分别在面部两侧进行MFR和NAFL治疗,间隔一个月。由两名独立整形外科医生以5分视觉模拟量表(VAS, 0-4)对光老化严重程度进行盲法结局评估。患者满意度也基于5点VAS评分(0 =不满意,4 =非常满意)。使用Antera 3D相机评估鼻唇沟下垂,使用VISIA皮肤分析系统评估面部皱纹和毛孔。研究期间发生的任何不良事件也被评估。根据VAS评分和Antera 3D和VISIA的结果,我们注意到与基线相比,面部皮肤松弛、皱纹和毛孔都有显著改善,面部MFR和NAFL两侧的鼻唇沟下垂较少。大多数患者对治疗满意,疼痛和结痂可耐受。虽然MFR和NAFL治疗之间没有显著差异,但NAFL治疗的停机时间(4.56±2.72d)比MFR治疗(6.96±3.27d)短。本研究证实了MFR和NAFL治疗亚洲患者面部皮肤年轻化的疗效。此外,这些疗法被发现是安全且耐受性良好的。我们的研究结果表明,NAFL可能是一种更方便的治疗面部光老化的方式,因为它的停机时间更短。然而,MFR治疗比NAFL治疗更能改善鼻唇沟下垂。
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引用次数: 4
Pulsed dye laser versus Nd:YAG laser in the treatment of recalcitrant plantar warts: an intraindividual comparative study. 脉冲染料激光与Nd:YAG激光治疗顽固性足底疣:个体比较研究。
IF 1.2 4区 医学 Q2 Medicine Pub Date : 2021-08-01 Epub Date: 2022-01-03 DOI: 10.1080/14764172.2021.2016843
Shady Mahmoud Attia Ibrahim, Mona Soliman, Sahar Khalaf Allah Mohamed, Mohamed Mohsen Soliman

Plantar warts are common cutaneous lesions caused by the human papillomavirus. Treatment of recalcitrant plantar warts stays a continuous challenge, and they are more refractory to treatment than common warts. To compare the efficacy of Long-Pulsed neodymium: yttrium-aluminum-garnet (Nd:YAG) laser versus pulsed dye laser (PDL) on the therapy of multiple recalcitrant plantar warts. Thirty patients with recalcitrant plantar warts were included in the current study. Half the number of warts were treated by PDL in each patient, while the other half were treated by Nd:YAG. Laser sessions were applied every 2 weeks for a maximum of six sessions. Patients were followed up both clinically and using dermoscopy. There was a complete clearance of warts in 20 patients (66.7%) with Nd:YAG laser and 19 patients (63.3%) with PDL with no statistically significant difference between both types of lasers. Pain during laser sessions was higher with Nd:YAG laser PDL and it was statistically significant (p = .0001). Both Nd:YAG laser and PDL showed efficacy and safety for the treatment of recalcitrant plantar warts. The use of dermoscopy adds great value in evaluating treatment response and in decreasing the incidence of recurrence.

足底疣是由人乳头瘤病毒引起的常见皮肤病变。治疗顽固性足底疣是一个持续的挑战,它们比普通疣更难以治疗。比较长脉冲钕钇铝石榴石激光(Nd:YAG)与脉冲染料激光(PDL)治疗多发性顽固性足底疣的疗效。本研究纳入了30例顽固性足底疣患者。每个患者一半的疣用PDL治疗,另一半用Nd:YAG治疗。激光治疗每2周进行一次,最多6次。对患者进行临床及皮肤镜随访。Nd:YAG激光治疗20例(66.7%)疣完全清除,PDL治疗19例(63.3%)疣完全清除,两种激光治疗差异无统计学意义。Nd:YAG激光PDL在激光治疗期间疼痛更高,具有统计学意义(p = 0.0001)。Nd:YAG激光和PDL治疗顽固性足底疣均有效、安全。皮肤镜检查在评估治疗效果和降低复发率方面具有很大的价值。
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引用次数: 5
期刊
Journal of Cosmetic and Laser Therapy
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