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Prevalence and predictors of bone mineral density testing after distal radius fracture in menopausal women
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-15 DOI: 10.1016/j.injury.2025.112219
Jessica M Welch , Christopher S Klifto , Kevin M Klifto , Kiera N Lunn , Kwabena Adu-Kwarteng , Warren C Hammert , Christian A Pean , Tyler S Pidgeon

Background

Osteoporosis screening guidelines recommend bone mineral density (BMD) testing following fragility fractures. Nevertheless, previous studies have demonstrated low rates of osteoporosis screening. Diagnosis and treatment of osteoporosis is essential for prevention of future fractures, however not much is known about the factors associated with receiving BMD testing in this patient population. The purpose of this study was to evaluate the prevalence, timing, and predictors of BMD testing following distal radius fractures (DRF) in menopausal women.

Methods

We queried a national insurance database to identify menopausal women aged 45–64 years with a DRF between years 2013 and 2020. The rate of BMD testing within 1 year of injury was calculated. Multivariable logistic regression analysis was used to evaluate the effect of patient- and injury-related variables on the likelihood of undergoing BMD testing following DRF.

Results

Among 31,728 patients meeting inclusion criteria (mean ± SD age: 57.5 ± 4.3), 3,886 (12.2 %) received a BMD test within 1 year following DRF. The rate of BMD tests decreased with the highest rate of 14.5 % in 2015 and the lowest rate of 10.5 % in 2020. Mean time from DRF to BMD testing was 143 ± 102 days. Patients aged 60–64 had the highest adjusted odds of receiving BMD testing (OR 2.85 [95 % CI: 2.26 to 3.64]). Factors associated with increased likelihood of BMD testing included surgical intervention (OR 1.38 [1.28–1.48]), rheumatoid arthritis (OR 1.22 [1.06–1.40]), osteoarthritis (OR 1.28 [1.19–1.37]), breast cancer (OR 1.35 [1.16–1.56]), and vitamin D deficiency (OR 1.29 [1.17–1.43]). Factors associated with decreased likelihood of testing included tobacco use (OR 0.90 [0.84–0.97]), patients with Medicaid (OR 0.73 [0.61–0.86]) or Medicare (OR 0.76 [0.65–0.88]) insurance, and living in Southern (OR 0.67 [0.62–0.73]) or Western (OR 0.69 [0.62–0.77]) regions of the United States. Obesity, diabetes, renal disease, and early menopause were not associated with BMD testing.

Conclusions

Despite guidelines recommending BMD testing after low-energy fractures, rates of BMD testing were low and decreased among menopausal women with DRF. Mean time to BMD testing was 4.7 months, indicating substantial delays in workup. Known risk factors for osteoporosis did not reliably predict likelihood of BMD testing.

Level of Evidence

Level III, prognostic
背景骨质疏松症筛查指南建议在发生脆性骨折后进行骨矿物质密度(BMD)检测。然而,以往的研究表明骨质疏松症筛查率很低。骨质疏松症的诊断和治疗对于预防未来骨折至关重要,但对于此类患者接受 BMD 检测的相关因素却知之甚少。本研究旨在评估绝经期女性桡骨远端骨折(DRF)后进行 BMD 检测的流行率、时间和预测因素。方法我们查询了一个全国性保险数据库,以确定在 2013 年至 2020 年间发生 DRF 的 45-64 岁绝经期女性。我们计算了受伤后 1 年内进行 BMD 检测的比例。结果在符合纳入标准的 31728 名患者(平均 ± SD 年龄:57.5 ± 4.3)中,有 3886 人(12.2%)在 DRF 后 1 年内接受了 BMD 检测。BMD 检测率有所下降,2015 年最高,为 14.5%,2020 年最低,为 10.5%。从 DRF 到 BMD 检测的平均时间为 143 ± 102 天。60-64 岁患者接受 BMD 检测的调整后几率最高(OR 2.85 [95 % CI:2.26 至 3.64])。与 BMD 检测几率增加相关的因素包括外科干预(OR 1.38 [1.28-1.48])、类风湿性关节炎(OR 1.22 [1.06-1.40])、骨关节炎(OR 1.28 [1.19-1.37])、乳腺癌(OR 1.35 [1.16-1.56])和维生素 D 缺乏(OR 1.29 [1.17-1.43])。与检测可能性降低相关的因素包括吸烟(OR 0.90 [0.84-0.97])、患者有医疗补助(OR 0.73 [0.61-0.86])或医疗保险(OR 0.76 [0.65-0.88])、居住在美国南部(OR 0.67 [0.62-0.73])或西部(OR 0.69 [0.62-0.77])地区。结论尽管指南建议在低能量骨折后进行 BMD 检测,但在患有 DRF 的更年期妇女中,BMD 检测率很低,且有所下降。进行 BMD 检测的平均时间为 4.7 个月,这表明检查工作严重滞后。已知的骨质疏松症风险因素并不能可靠地预测进行 BMD 检测的可能性。
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引用次数: 0
A nurse-led approach to enhancing foot and ankle tissue repair: A study using fibroblast growth factor and skin flap technique
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-12 DOI: 10.1016/j.injury.2025.112213
Fan Yang , Jing Dong , Jing Hu, Zhezhen Jiang, Regis Ernest Mendame Ehya

Introduction

Foot and ankle soft tissue defects with exposed bone pose significant challenges in wound healing and patient satisfaction

Objective

The study aims to assess the impact of nursing care quality and patient satisfaction on optimizing outcomes for complex foot and ankles injuries, focusing on the timing of rh-FGF administration after reconstructive surgery

Methods

This study included eighteen patients (15 males and 3 females) with traumatic foot and ankle soft tissue defects and exposed bone wounds, treated between January 2021 and December 2022. Patients were randomly assigned to three groups, underwent reconstructive surgery, and received rh-bFGF at varying times postoperatively. Key outcomes included wound healing time, hospital stay duration, satisfaction with nursing care scale, American Orthopedic Foot and Ankle Society (AOFAS) score, and Visual Analogue Scale for pain. All patients were followed for at least three months

Results

The study population had an average age of 41.1 years, with a range from 16 to 74 years. Findings indicated an average hospital stay of 17 days and a corresponding wound healing time of 17 days. At three months post-operation, the average American Orthopedic Foot and Ankle Society (AOFAS) score was 88. A notable 88.9 % of patients expressed satisfaction with the attentiveness of nursing staff and the privacy afforded to them. Furthermore, 84.3 % rated the nurses’ competence positively, and 83.3 % appreciated the support provided to family and friends, along with personalized care and nurses’ expertise in patient management. The results demonstrated a consistent trend of improvement in all assessed outcomes across the three treatment groups. Patients in Group 1, who received rh-bFGF one day after surgery, demonstrated the most favorable outcomes. This was followed by Group 3, which received rh-bFGF until ischemic changes were noted. In contrast, Group 2, which received rh-bFGF once inflammatory granulation had subsided, exhibited the least improvement

Conclusion

The results of this study highlight the crucial role of timing in the administration of rh-bFGF for optimizing soft tissue repair in patients with foot and ankle defects. Timely application of rh-bFGF post-surgery is essential for achieving favorable patient outcomes, improving patient satisfaction with nursing care, and facilitating faster recovery.
引言足踝软组织缺损伴骨外露给伤口愈合和患者满意度带来了巨大挑战,本研究旨在评估护理质量和患者满意度对优化复杂足踝损伤预后的影响,重点关注重建手术后给予 rh-FGFF 的时机。患者被随机分配到三组,接受重建手术,并在术后不同时间接受 rh-bFGF 治疗。主要结果包括伤口愈合时间、住院时间、护理满意度量表、美国骨科足踝协会(AOFAS)评分和疼痛视觉模拟量表。所有患者均接受了至少三个月的随访。研究对象的平均年龄为 41.1 岁,年龄范围在 16 岁至 74 岁之间。结果显示,平均住院时间为 17 天,相应的伤口愈合时间为 17 天。术后三个月,美国足踝矫形协会(AOFAS)的平均评分为 88 分。88.9%的患者对护理人员的细心和隐私保护表示满意。此外,84.3% 的患者对护士的能力给予了积极评价,83.3% 的患者对护士为患者家人和朋友提供的支持、个性化护理以及护士在患者管理方面的专业知识表示赞赏。结果显示,三个治疗组的所有评估结果都呈现出一致的改善趋势。术后一天接受 rh-bFGF 治疗的第一组患者的疗效最好。紧随其后的是第 3 组,该组患者接受 rh-bFGF 治疗直至出现缺血性改变。结论:本研究的结果突出表明,rh-bFGF 的应用时机对于优化足踝缺损患者的软组织修复至关重要。术后及时应用 rh-bFGF 对实现良好的患者预后、提高患者对护理的满意度以及促进患者更快康复至关重要。
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引用次数: 0
Incidence of venous thromboembolism following achilles tendon rupture. Data from the UK foot and ankle thrombo-embolism (UK-FATE) audit
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-12 DOI: 10.1016/j.injury.2025.112212
Matthew Solan , Samuel Briggs-Price , Linzy Houchen-Wolloff , Karan Malhotra , Lyndon Mason , Jitendra Mangwani , UK FATE Collaborative

Introduction

Achilles tendon rupture (ATR) carries a high risk of venous thrombo-embolism (VTE) whether the injury is managed surgically or non-operatively. This study reports symptomatic VTE rate following ATR. The influence of patient demographics, treatment type and use of chemical thromboprophylaxis is examined.

Materials and Methods

Observational cohort study. The data is from a multi-centre, prospective, national audit of patients from 68 participating United Kingdom centres. Data was prospectively collected from hospital records. The study was conducted between June and November 2022, with a 3-month follow up.

Results

Of 11,363 participants in the National Audit, 9.5 % (n = 1084) had experienced an ATR. Management strategies included both non-surgical (74 %) and surgical (26 %). Following ATR, the VTE rate was 3.69 % (n = 40) compared to 0.57 % (n = 59) for other foot and ankle surgeries.
Participants who developed symptomatic VTE after ATR were older than those who did not (mean age 54 years (95 %CI 50.5 - 54.7) vs 48 years (95 %CI 47.3 - 49.1)). There was no significant difference in VTE events due to participant sex, ethnicity or number of comorbidities. Differences in treatment regimen, such as weight-bearing status and immobilisation strategy, showed no significant difference in symptomatic VTE events between groups.

Conclusion

After ATR, patients are 6.5-times more likely to experience symptomatic VTE than those recovering from surgery for other foot and ankle pathology. There was no significant difference in symptomatic VTE rate after ATR with specific chemical prophylaxis or early mobilisation strategies.
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引用次数: 0
Classifications and treatment management of fragility fracture of the pelvis: A scoping review
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-09 DOI: 10.1016/j.injury.2025.112206
Kaori Endo , Norio Yamamoto , Shunsuke Taito , Takahiro Tsuge , Yuki Nakashima , Kosuke Suzuki , Takao Kaneko , Kae Okoshi

Background

Fragility fractures of the pelvis (FFP) present a growing challenge in aging populations. However, standardized classifications and treatment guidelines remain scarce.

Objective

This scoping review examines the application of fracture classifications, treatment strategies, and outcome evaluations for FFP, identifying gaps in the literature, and suggesting directions for future research.

Methods

A systematic search of multiple electronic databases yielded 117 studies discussing FFP names, classifications, treatment approaches, and outcomes. Data extraction focused on study characteristics, classification systems, treatment details, outcomes, and follow-up periods. Residual analysis using the Chi-square test assessed statistical associations and underrepresentation.

Results

The FFP classification was the most common (51.3%), with additional treatment indicators focused on immobility (44.4%) and pain assessment (using the Visual Analog Scale [VAS] or Numeric Rating Scale [NRS], 37.6%), consistent with existing guidelines. In contrast, the sacral insufficient fractures were statistically associated with pain indications but lacked corresponding classification application. Initial management typically involved conservative or observation period. Regarding the management indications and outcomes, surgical interventions were categorized into osteosynthesis and sacroplasty. Outcome evaluations often incorporated mobility and functional status (59.0%), hospitalization length (49.6%), mortality rates (41.0%), and post-treatment living conditions (41.0%). Patient recovery was assessed through VAS scores (59.0%) and Activities of Daily Living Patient-Reported Outcomes (ADL-PROs, 34.2%). However, inconsistencies in standardized outcomes, particularly in sacroplasty studies, hinder comparative analysis.

Conclusion

FFP classifications, along with pain and mobility assessments, were frequently applied as management indicators for FFP. Standardizing treatment indications and establishing consistent outcome measures, including the evidenced gap treatments (sacral insufficient fracture and cement augmentation), could significantly improve comparability across studies.
背景骨盆脆性骨折(FFP)是老龄化人群面临的一项日益严峻的挑战。然而,标准化的分类和治疗指南仍然匮乏。本范围综述研究了骨盆脆性骨折的骨折分类、治疗策略和结果评估的应用,找出了文献中的不足,并提出了未来的研究方向。方法通过对多个电子数据库进行系统检索,得出了 117 项讨论骨盆脆性骨折名称、分类、治疗方法和结果的研究。数据提取的重点是研究特点、分类系统、治疗细节、结果和随访期。结果 FFP分类是最常见的(51.3%),其他治疗指标主要集中在不能移动(44.4%)和疼痛评估(使用视觉模拟量表[VAS]或数字评分量表[NRS],37.6%),与现有指南一致。相比之下,骶骨不完全骨折在统计学上与疼痛指征相关,但缺乏相应的分类应用。最初的治疗通常为保守治疗或观察治疗。关于治疗适应症和结果,手术干预分为骨合成术和骶骨成形术。结果评估通常包括活动能力和功能状态(59.0%)、住院时间(49.6%)、死亡率(41.0%)和治疗后的生活条件(41.0%)。患者康复情况通过 VAS 评分(59.0%)和日常生活活动患者报告结果(ADL-PROs,34.2%)进行评估。然而,标准化结果的不一致性,尤其是骶骨成形术研究中的不一致性,阻碍了比较分析的进行。规范治疗适应症并建立一致的结果衡量标准,包括证据差距治疗(骶骨不完全骨折和骨水泥增强),可显著提高各研究的可比性。
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引用次数: 0
Effects of acute intermittent hypoxia on muscle strength in individuals with spinal cord injury: A systematic review of randomized trials
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-09 DOI: 10.1016/j.injury.2025.112211
Anas R. Alashram

Introduction

Muscle weakness is among the most common motor deficits in individuals with spinal cord injury (SCI). Acute intermittent hypoxia (AIH) has been used to improve motor function by facilitating neuroplasticity. The purpose of this systematic review is to explore the impacts of AIH on muscle strength in individuals with SCI, identify who would most likely respond well to the intervention, and determine the optimal therapeutic protocol.

Methods

Relevant literature was explored in “PubMed, MEDLINE, The Cochrane Library, Scopus, PEDro, and Web of Science” databases until October 2024. Randomized trials that involved SCI patients who underwent AIH, compared with controls, and assessed muscle strength were included in this review. The methodological quality was assessed using the “Physiotherapy Evidence Database (PEDro)” scale. The effect sizes were calculated using Cohen's d.

Results

Of 502 studies, seven studies met the eligibility criteria, and the sample sizes ranged from 12 to 28 participants across the included studies. In total, 146 SCI patients (mean age 46.76 years; 88 % male) were included in this systematic review. The PEDro scores of the studies included varied between 5 and 8, with a median score of 8.

Conclusions

AIH is a promising therapeutic modality for enhancing muscle strength post-SCI, specifically in patients with motor-incomplete injuries. Based on good quality studies, delivering AIH independently or in combination with other treatments for 15 short (60–90 s) episodes of hypoxic exposure (Oxygen = 9 %) alternating with 15 (60–90 s) normoxic episodes (Oxygen = 21 %), across one or more sessions, could yield meaningful outcomes. Nevertheless, the evidence is limited by treatment protocol variations, small sample sizes, and a lack of standardization in combining AIH with other treatments. Therefore, further studies with larger sample sizes, more diverse populations, and standardized treatment protocols are strongly needed to verify our findings. Future studies should also address the potential bias, examine the long-term effects, and investigate underlying mechanisms to provide more generalized evidence.
{"title":"Effects of acute intermittent hypoxia on muscle strength in individuals with spinal cord injury: A systematic review of randomized trials","authors":"Anas R. Alashram","doi":"10.1016/j.injury.2025.112211","DOIUrl":"10.1016/j.injury.2025.112211","url":null,"abstract":"<div><h3>Introduction</h3><div>Muscle weakness is among the most common motor deficits in individuals with spinal cord injury (SCI). Acute intermittent hypoxia (AIH) has been used to improve motor function by facilitating neuroplasticity. The purpose of this systematic review is to explore the impacts of AIH on muscle strength in individuals with SCI, identify who would most likely respond well to the intervention, and determine the optimal therapeutic protocol.</div></div><div><h3>Methods</h3><div>Relevant literature was explored in “PubMed, MEDLINE, The Cochrane Library, Scopus, PEDro, and Web of Science” databases until October 2024. Randomized trials that involved SCI patients who underwent AIH, compared with controls, and assessed muscle strength were included in this review. The methodological quality was assessed using the “Physiotherapy Evidence Database (PEDro)” scale. The effect sizes were calculated using Cohen's d<em>.</em></div></div><div><h3>Results</h3><div>Of 502 studies, seven studies met the eligibility criteria, and the sample sizes ranged from 12 to 28 participants across the included studies. In total, 146 SCI patients (mean age 46.76 years; 88 % male) were included in this systematic review. The PEDro scores of the studies included varied between 5 and 8, with a median score of 8.</div></div><div><h3>Conclusions</h3><div>AIH is a promising therapeutic modality for enhancing muscle strength post-SCI, specifically in patients with motor-incomplete injuries. Based on good quality studies, delivering AIH independently or in combination with other treatments for 15 short (60–90 s) episodes of hypoxic exposure (Oxygen = 9 %) alternating with 15 (60–90 s) normoxic episodes (Oxygen = 21 %), across one or more sessions, could yield meaningful outcomes. Nevertheless, the evidence is limited by treatment protocol variations, small sample sizes, and a lack of standardization in combining AIH with other treatments. Therefore, further studies with larger sample sizes, more diverse populations, and standardized treatment protocols are strongly needed to verify our findings. Future studies should also address the potential bias, examine the long-term effects, and investigate underlying mechanisms to provide more generalized evidence.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112211"},"PeriodicalIF":2.2,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Damage control orthopedics versus early total care of femur fracture in a national cohort of pediatric patients with traumatic brain injury
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-08 DOI: 10.1016/j.injury.2025.112210
Cailan L. Feingold , Jose Dominguez , Michael Jacoby , Harshadkumar A. Patel , Damon Delbello , Irim Salik

Background

Long bone fracture is one of the most common concomitant injuries in pediatric traumatic brain injury (TBI) patients, requiring surgical intervention in the form of intramedullary nailing (IMN), open reduction and internal fixation (ORIF), or temporary external fixation, otherwise known as damage control orthopedics (DCO), for transient stabilization before definitive repair. There are no definitive guidelines for femur fracture management in polytrauma TBI pediatric patients. This study investigates the outcomes of patients with TBI and femur fractures who underwent DCO versus early total care (ETC), hypothesizing that delayed fracture fixation is associated with worse outcomes.

Methods

Pediatric patients admitted with TBI who underwent femur fracture repair between 2016 and 2020 were investigated using the National Inpatient Sample database. Clinical outcomes, healthcare utilization data, baseline demographics, and comorbidities were collected. All Patient Refined Diagnosis Related Groups (APR-DRG) severity was defined for each case. The injury severity scale (ISS) was developed using ICD-10-CM codes for injury. High ISS was defined as greater than 75th percentile. DCO patients were compared with ETC patients. Inpatient death, prolonged LOS, and high total charges were the primary outcomes evaluated. Multivariate binary logistic regression analysis was used to evaluate for independent predictors of primary outcomes.

Results

A total of 6,775 pediatric TBI patients under the age of 21 who underwent repair of femur fracture were identified. The average age was 15.5 years (range: 0–21 years) and there were 2,065 (30.5 %) females. DCO to treat femur fractures was employed in 1,010 (14.9 % of patients). Patients undergoing DCO were significantly more likely to have extreme illness severity (OR = 3.049), early trauma complications (OR = 2.273), and respiratory complications (OR = 2.255). DCO was independently associated with prolonged length of stay (LOS) (OR = 1.263), high total charges (OR = 1.786), and inpatient death (OR = 2.796).

Conclusion

This study found that DCO is associated with worse outcomes, likely secondary to injury severity and underlying neurologic injury of patients undergoing DCO. These findings suggest it is time to definitively outline the timing and modality of femur fracture repair for the polytrauma pediatric patient with TBI.

Level of evidence

III.
{"title":"Damage control orthopedics versus early total care of femur fracture in a national cohort of pediatric patients with traumatic brain injury","authors":"Cailan L. Feingold ,&nbsp;Jose Dominguez ,&nbsp;Michael Jacoby ,&nbsp;Harshadkumar A. Patel ,&nbsp;Damon Delbello ,&nbsp;Irim Salik","doi":"10.1016/j.injury.2025.112210","DOIUrl":"10.1016/j.injury.2025.112210","url":null,"abstract":"<div><h3>Background</h3><div>Long bone fracture is one of the most common concomitant injuries in pediatric traumatic brain injury (TBI) patients, requiring surgical intervention in the form of intramedullary nailing (IMN), open reduction and internal fixation (ORIF), or temporary external fixation, otherwise known as damage control orthopedics (DCO), for transient stabilization before definitive repair. There are no definitive guidelines for femur fracture management in polytrauma TBI pediatric patients. This study investigates the outcomes of patients with TBI and femur fractures who underwent DCO versus early total care (ETC), hypothesizing that delayed fracture fixation is associated with worse outcomes.</div></div><div><h3>Methods</h3><div>Pediatric patients admitted with TBI who underwent femur fracture repair between 2016 and 2020 were investigated using the National Inpatient Sample database. Clinical outcomes, healthcare utilization data, baseline demographics, and comorbidities were collected. All Patient Refined Diagnosis Related Groups (APR-DRG) severity was defined for each case. The injury severity scale (ISS) was developed using ICD-10-CM codes for injury. High ISS was defined as greater than 75th percentile. DCO patients were compared with ETC patients. Inpatient death, prolonged LOS, and high total charges were the primary outcomes evaluated. Multivariate binary logistic regression analysis was used to evaluate for independent predictors of primary outcomes.</div></div><div><h3>Results</h3><div>A total of 6,775 pediatric TBI patients under the age of 21 who underwent repair of femur fracture were identified. The average age was 15.5 years (range: 0–21 years) and there were 2,065 (30.5 %) females. DCO to treat femur fractures was employed in 1,010 (14.9 % of patients). Patients undergoing DCO were significantly more likely to have extreme illness severity (OR = 3.049), early trauma complications (OR = 2.273), and respiratory complications (OR = 2.255). DCO was independently associated with prolonged length of stay (LOS) (OR = 1.263), high total charges (OR = 1.786), and inpatient death (OR = 2.796).</div></div><div><h3>Conclusion</h3><div>This study found that DCO is associated with worse outcomes, likely secondary to injury severity and underlying neurologic injury of patients undergoing DCO. These findings suggest it is time to definitively outline the timing and modality of femur fracture repair for the polytrauma pediatric patient with TBI.</div></div><div><h3>Level of evidence</h3><div>III.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112210"},"PeriodicalIF":2.2,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Operatively treated high-energy blunt pelvic ring injuries and surgical site infections – A retrospective assessment based on a prospective registry
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-08 DOI: 10.1016/j.injury.2025.112209
Elvin Gurbanov , Ulysse Coneys , Elisabeth Andereggen , Alexandre Ansorge , Vanessa Morello , Axel Gamulin

Introduction

High-energy pelvic ring injuries (PRI) are severe, life-threatening trauma conditions which might require complex surgical management. One of the major complications associated with these injuries is the development of surgical site infections (SSI) which significantly impact patient outcomes. This study aimed to evaluate the rate of SSI in patients undergoing surgical fixation of high-energy blunt PRI and identify the key predisposing factors.

Methods

A retrospective review of patients treated for high-energy blunt PRI was conducted using the prospectively filled institutional Severely Injured Patients’ Registry, focusing on the rate of SSI following surgical fixation. The multifactorial nature of infection risk was analyzed, with particular attention to the type of injury, surgical technique, external fixation devices’ usage and the germs encountered.

Results

A SSI rate of 10,5 % (12 out of 114 patients) was encountered among the study population. The primary SSI risk factor was PRI complexity; 83.3 % of patients with SSI had an AO/OTA type C fracture and 16.7 % a type B fracture, while 43.1 % of patients without SSI had a type C fracture and 56.9 % a type B fracture (p = 0.008). Additionally, SSI patients had a trend to have higher extremities/pelvis AIS and higher ISS, and to have been more often treated with a transient pelvic fixation device including supra-acetabular external fixator.

Conclusion

These findings emphasize the need for a comprehensive infection prevention strategy in high-energy PRI patients, especially in complex cases. A multidisciplinary approach is of outmost importance and should include surgical techniques with meticulous soft tissue handling, proper implant selection and aggressive post-operative wound care. Despite external fixation devices being related to certain cases of SSI, their life-saving potential during the initial management phase should be carefully weighed against this risk.
{"title":"Operatively treated high-energy blunt pelvic ring injuries and surgical site infections – A retrospective assessment based on a prospective registry","authors":"Elvin Gurbanov ,&nbsp;Ulysse Coneys ,&nbsp;Elisabeth Andereggen ,&nbsp;Alexandre Ansorge ,&nbsp;Vanessa Morello ,&nbsp;Axel Gamulin","doi":"10.1016/j.injury.2025.112209","DOIUrl":"10.1016/j.injury.2025.112209","url":null,"abstract":"<div><h3>Introduction</h3><div>High-energy pelvic ring injuries (PRI) are severe, life-threatening trauma conditions which might require complex surgical management. One of the major complications associated with these injuries is the development of surgical site infections (SSI) which significantly impact patient outcomes. This study aimed to evaluate the rate of SSI in patients undergoing surgical fixation of high-energy blunt PRI and identify the key predisposing factors.</div></div><div><h3>Methods</h3><div>A retrospective review of patients treated for high-energy blunt PRI was conducted using the prospectively filled institutional <em>Severely Injured Patients’ Registry</em>, focusing on the rate of SSI following surgical fixation. The multifactorial nature of infection risk was analyzed, with particular attention to the type of injury, surgical technique, external fixation devices’ usage and the germs encountered.</div></div><div><h3>Results</h3><div>A SSI rate of 10,5 % (12 out of 114 patients) was encountered among the study population. The primary SSI risk factor was PRI complexity; 83.3 % of patients with SSI had an AO/OTA type C fracture and 16.7 % a type B fracture, while 43.1 % of patients without SSI had a type C fracture and 56.9 % a type B fracture (<em>p</em> = 0.008). Additionally, SSI patients had a trend to have higher extremities/pelvis AIS and higher ISS, and to have been more often treated with a transient pelvic fixation device including supra-acetabular external fixator.</div></div><div><h3>Conclusion</h3><div>These findings emphasize the need for a comprehensive infection prevention strategy in high-energy PRI patients, especially in complex cases. A multidisciplinary approach is of outmost importance and should include surgical techniques with meticulous soft tissue handling, proper implant selection and aggressive post-operative wound care. Despite external fixation devices being related to certain cases of SSI, their life-saving potential during the initial management phase should be carefully weighed against this risk.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112209"},"PeriodicalIF":2.2,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for cut-throughs in intertrochanteric hip fracture fixation Tip-Apex Distance (TAD) <10 mm and Apex-to-Center <4 mm
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-07 DOI: 10.1016/j.injury.2025.112205
Arielle Richey Levine, Trevan Klug, James Cross, Motasem Salameh, Matthew Riedel, Michael Leslie

Objectives

TAD > 25 mm is a risk factor for cut-out in intramedullary nailing. Less attention has been given to the risk factors for central cut-through and the possible outcomes of TAD <10 mm. Furthermore, the risk of cut-through depending on minimum depth on either anterior-posterior (AP) or lateral views has not been explored. The goal of this study is to outline the parameters that increase risk of cut-through in intertrochanteric hip fractures.

Methods

A retrospective review of 2128 intertrochanteric hip fractures admitted to a single level 1 academic trauma center from 2014 – 2023 was conducted. Variables included patient and operative characteristics, fracture fixation device, fracture type based on OTA/AO 2018 classification, TAD, neck-shaft angle and radiographic and clinical outcomes.

Results

TAD <10 millimeters carried a significantly higher risk for lag screw and blade cut-through. Cut-through risk increased significantly when either AP or lateral apex-to-center distance was <4 millimeters, including when comparing fracture reduction quality for a cohort including sliding hip screws, lag screws and blades. Cut-out complications in this cohort only occurred with a TAD >10 mm and was significantly more likely to occur with TAD >25 mm, similar to prior studies.

Conclusion

TAD optimization between 10 and 25 mm reduces risk of both cut-out and cut-through and maintenance of 4 mm of distance between apex-to-center distance may help decrease the risk of cut-through complications.
{"title":"Risk factors for cut-throughs in intertrochanteric hip fracture fixation Tip-Apex Distance (TAD) <10 mm and Apex-to-Center <4 mm","authors":"Arielle Richey Levine,&nbsp;Trevan Klug,&nbsp;James Cross,&nbsp;Motasem Salameh,&nbsp;Matthew Riedel,&nbsp;Michael Leslie","doi":"10.1016/j.injury.2025.112205","DOIUrl":"10.1016/j.injury.2025.112205","url":null,"abstract":"<div><h3>Objectives</h3><div>TAD &gt; 25 mm is a risk factor for cut-out in intramedullary nailing. Less attention has been given to the risk factors for central cut-through and the possible outcomes of TAD &lt;10 mm. Furthermore, the risk of cut-through depending on minimum depth on either anterior-posterior (AP) or lateral views has not been explored. The goal of this study is to outline the parameters that increase risk of cut-through in intertrochanteric hip fractures.</div></div><div><h3>Methods</h3><div>A retrospective review of 2128 intertrochanteric hip fractures admitted to a single level 1 academic trauma center from 2014 – 2023 was conducted<strong>.</strong> Variables included patient and operative characteristics, fracture fixation device, fracture type based on OTA/AO 2018 classification, TAD, neck-shaft angle and radiographic and clinical outcomes.</div></div><div><h3>Results</h3><div>TAD &lt;10 millimeters carried a significantly higher risk for lag screw and blade cut-through. Cut-through risk increased significantly when either AP or lateral apex-to-center distance was &lt;4 millimeters, including when comparing fracture reduction quality for a cohort including sliding hip screws, lag screws and blades. Cut-out complications in this cohort only occurred with a TAD &gt;10 mm and was significantly more likely to occur with TAD &gt;25 mm, similar to prior studies.</div></div><div><h3>Conclusion</h3><div>TAD optimization between 10 and 25 mm reduces risk of both cut-out and cut-through and maintenance of 4 mm of distance between apex-to-center distance may help decrease the risk of cut-through complications.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112205"},"PeriodicalIF":2.2,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient reported outcome scores following traumatic hip dislocations
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-06 DOI: 10.1016/j.injury.2025.112197
Carlo Eikani , Elizabeth Cho , Robert Kelly , Robert Hand , Joseph Cohen , Hobie Summers , Ashley E. Levack

Objective

Traumatic native hip dislocations require immediate orthopaedic attention and have been associated with significant long-term morbidity. Previous studies have reported radiographic outcomes and clinical complication rates, however; evidence evaluating the effect of these injuries on patient-reported outcomes (PROs) is limited. The purpose of our study was to evaluate PRO scores among patients with native hip dislocations.

Methods

Adult patients with native hip dislocations between 2005 and 2020 at a single academic Level 1 trauma center were retrospectively reviewed. Radiographs and medical records were reviewed for patient demographics and comorbidities, injury characteristics, details of treatment including time to reduction, and complications. Patients were given the PROMIS Physical Function (PROMIS PF) and Short Form-36 (SF-36) via HIPAA compliant electronic data capture. Outcomes were analyzed using Student t-tests and Mann-Whitney U comparisons of means/medians. Floor and ceiling effects were also characterized for the various outcomes scores.

Results

A total of 168 patients with native hip dislocation were identified, 78 (46.4 %) of whom completed all PROs measures. Among responders, mean age was 36.2 years (SD 14.5), mean BMI was 29.2 (SD 6.7), and mean dislocation duration was 8.9 h (SD 5.1). On univariable regression, older age was associated with worse SF-36 Physical scores (p = 0.007). PROMIS PF showed an estimated 2.18 decrease for every one grade increase in Kellgren-Lawrence score (p = 0.01). There were no ceiling or floor effects seen with PROMIS PF, SF-36 Physical Summary, or SF-36 Mental Summary Scores.

Conclusions

Patients of older age and higher Kellgren-Lawrence score exhibited worse SF-36 Physical Function and PROMIS PF scores, respectively, highlighting the functional impact that native hip dislocations may have. PROMIS PF, SF-36 Physical and Mental Summary Scores were without floor or ceiling effects, rendering this an important tool in the evaluation of patients with traumatic native hip dislocation.
{"title":"Patient reported outcome scores following traumatic hip dislocations","authors":"Carlo Eikani ,&nbsp;Elizabeth Cho ,&nbsp;Robert Kelly ,&nbsp;Robert Hand ,&nbsp;Joseph Cohen ,&nbsp;Hobie Summers ,&nbsp;Ashley E. Levack","doi":"10.1016/j.injury.2025.112197","DOIUrl":"10.1016/j.injury.2025.112197","url":null,"abstract":"<div><h3>Objective</h3><div>Traumatic native hip dislocations require immediate orthopaedic attention and have been associated with significant long-term morbidity. Previous studies have reported radiographic outcomes and clinical complication rates, however; evidence evaluating the effect of these injuries on patient-reported outcomes (PROs) is limited. The purpose of our study was to evaluate PRO scores among patients with native hip dislocations.</div></div><div><h3>Methods</h3><div>Adult patients with native hip dislocations between 2005 and 2020 at a single academic Level 1 trauma center were retrospectively reviewed. Radiographs and medical records were reviewed for patient demographics and comorbidities, injury characteristics, details of treatment including time to reduction, and complications. Patients were given the PROMIS Physical Function (PROMIS PF) and Short Form-36 (SF-36) via HIPAA compliant electronic data capture. Outcomes were analyzed using Student <em>t</em>-tests and Mann-Whitney U comparisons of means/medians. Floor and ceiling effects were also characterized for the various outcomes scores.</div></div><div><h3>Results</h3><div>A total of 168 patients with native hip dislocation were identified, 78 (46.4 %) of whom completed all PROs measures. Among responders, mean age was 36.2 years (SD 14.5), mean BMI was 29.2 (SD 6.7), and mean dislocation duration was 8.9 h (SD 5.1). On univariable regression, older age was associated with worse SF-36 Physical scores (<em>p</em> = 0.007). PROMIS PF showed an estimated 2.18 decrease for every one grade increase in Kellgren-Lawrence score (<em>p</em> = 0.01). There were no ceiling or floor effects seen with PROMIS PF, SF-36 Physical Summary, or SF-36 Mental Summary Scores.</div></div><div><h3>Conclusions</h3><div>Patients of older age and higher Kellgren-Lawrence score exhibited worse SF-36 Physical Function and PROMIS PF scores, respectively, highlighting the functional impact that native hip dislocations may have. PROMIS PF, SF-36 Physical and Mental Summary Scores were without floor or ceiling effects, rendering this an important tool in the evaluation of patients with traumatic native hip dislocation.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112197"},"PeriodicalIF":2.2,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing pelvic fracture care: The impact of extraperitoneal pelvic packing on definitive Orthopaedic treatment
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2025-02-04 DOI: 10.1016/j.injury.2025.112207
Francesco Addevico , Michele Altomare , Umberto Mezzadri , Alberto Nicolò Bergamini , Sara Gianna Salvadori , Federico Bove , Stefania Cimbanassi
This study investigates the impact of extraperitoneal pelvic packing (EPP) on the definitive surgical treatment of pelvic fractures (PF) in trauma patients. While EPP is recognized as an effective life-saving technique for controlling non-compressible retroperitoneal bleeding, concerns persist about its potential to complicate subsequent surgical interventions.
A total of 220 trauma patients treated in a single First Level Trauma Centre from October 2016 to December 2021 were analysed. Demographic data, trauma mechanisms, hemodynamic stability, Injury Severity Scores (ISS), New ISS, PF classification (Tile), surgical timelines, and postoperative complications according to the Clavien-Dindo classification were collected. The study population was divided into two groups: those who underwent EPP (n = 42) and those who did not (n = 178). Statistical analyses included propensity score matching to balance baseline characteristics and reduce selection bias.
Key findings show that EPP effectively improved survival rates in hemodynamically unstable patients, achieving a survival rate of 71.43 %. However, EPP was associated with delays in definitive surgical treatment and a higher incidence of major postoperative complications (41.67 % vs. 17.65 %, p = 0.014). Despite these delays, EPP did not significantly limit the possibility of achieving definitive surgery or the choice of fixation technique. Patients who underwent both EPP and open reduction internal fixation did not show a higher rate of severe complications compared to those managed without EPP.
The study concludes that while EPP should be considered a practical emergency intervention for critically unstable PF patients, and even though it may affect the timing of definitive PF treatment, it does not prevent further surgical management.
{"title":"Enhancing pelvic fracture care: The impact of extraperitoneal pelvic packing on definitive Orthopaedic treatment","authors":"Francesco Addevico ,&nbsp;Michele Altomare ,&nbsp;Umberto Mezzadri ,&nbsp;Alberto Nicolò Bergamini ,&nbsp;Sara Gianna Salvadori ,&nbsp;Federico Bove ,&nbsp;Stefania Cimbanassi","doi":"10.1016/j.injury.2025.112207","DOIUrl":"10.1016/j.injury.2025.112207","url":null,"abstract":"<div><div>This study investigates the impact of extraperitoneal pelvic packing (EPP) on the definitive surgical treatment of pelvic fractures (PF) in trauma patients. While EPP is recognized as an effective life-saving technique for controlling non-compressible retroperitoneal bleeding, concerns persist about its potential to complicate subsequent surgical interventions.</div><div>A total of 220 trauma patients treated in a single First Level Trauma Centre from October 2016 to December 2021 were analysed. Demographic data, trauma mechanisms, hemodynamic stability, Injury Severity Scores (ISS), New ISS, PF classification (Tile), surgical timelines, and postoperative complications according to the Clavien-Dindo classification were collected. The study population was divided into two groups: those who underwent EPP (<em>n</em> = 42) and those who did not (<em>n</em> = 178). Statistical analyses included propensity score matching to balance baseline characteristics and reduce selection bias.</div><div>Key findings show that EPP effectively improved survival rates in hemodynamically unstable patients, achieving a survival rate of 71.43 %. However, EPP was associated with delays in definitive surgical treatment and a higher incidence of major postoperative complications (41.67 % vs. 17.65 %, <em>p</em> = 0.014). Despite these delays, EPP did not significantly limit the possibility of achieving definitive surgery or the choice of fixation technique. Patients who underwent both EPP and open reduction internal fixation did not show a higher rate of severe complications compared to those managed without EPP.</div><div>The study concludes that while EPP should be considered a practical emergency intervention for critically unstable PF patients, and even though it may affect the timing of definitive PF treatment, it does not prevent further surgical management.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"56 3","pages":"Article 112207"},"PeriodicalIF":2.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Injury-International Journal of the Care of the Injured
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