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Women undergoing primary total hip arthroplasty (THA) for hip fracture have lower in-hospital mortality compared to men 与男性相比,因髋部骨折接受初级全髋关节置换术(THA)的女性住院死亡率较低
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-19 DOI: 10.1016/j.injury.2024.111970
Sumanth R. Chandrupatla , Jasvinder A. Singh

Introduction

We evaluated the association of patient sex with in-patient mortality and discharge disposition after primary total hip arthroplasty (THA) for hip fracture in the U.S.

Methods

Using the 2016–2019 U.S. National Inpatient Sample (NIS), we calculated adjusted odds ratios (aOR) and 95% confidence intervals (CI) of the association of sex with post-procedural complications and in-hospital mortality after primary THA for hip fracture, adjusting for demographics, social determinants of health, medical comorbidity, hospital characteristics, and post-procedural complications.

Results

There were 400,930 primary THA procedure hospitalizations for hip fracture in the 2016–2019 NIS data. In multivariable-adjusted analysis, compared to males, female sex was associated with lower in-hospital mortality following THA for hip fracture (aOR 0.65, 95 % CI 0.58 - 0.74; p < 0.001). Multivariable-adjusted analysis showed that female sex was associated with higher odds of discharge to a non-home destination after a THA for hip fracture (aOR 1.14, 95 % CI 1.07 - 1.22; p < 0.001).

Conclusions

Female sex was associated with lower in-hospital mortality after a THA for hip fracture. Further insights into the protective mechanisms that mediate this lower mortality in women undergoing a THA for hip fracture are needed to achieve better outcomes for men in the future.
导言我们评估了患者性别与美国髋部骨折初级全髋关节置换术(THA)后住院死亡率和出院处置的关系。方法利用 2016-2019 年美国全国住院患者样本 (NIS),我们计算了性别与髋部骨折原发性全髋关节置换术后并发症和住院死亡率的调整赔率比 (aOR) 和 95% 置信区间 (CI),并对人口统计学、健康的社会决定因素、医疗合并症、医院特征和术后并发症进行了调整。结果在 2016-2019 年 NIS 数据中,共有 400,930 例髋部骨折原发性全髋关节置换术住院患者。在多变量调整分析中,与男性相比,女性与髋部骨折 THA 术后较低的院内死亡率相关(aOR 0.65,95 % CI 0.58 - 0.74;p <0.001)。结论女性与髋部骨折 THA 术后较低的院内死亡率相关。要想在未来为男性取得更好的治疗效果,还需要进一步深入了解女性在接受髋部骨折 THA 术后死亡率降低的保护机制。
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引用次数: 0
Recovery after neurologic injury in operative acetabular and pelvic fractures: Defining the natural history of foot drop 髋臼和骨盆骨折术后神经损伤的恢复:确定足下垂的自然史
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-19 DOI: 10.1016/j.injury.2024.111974
Colby C. Wollenman , Cade A. Morris , Ridge Maxson , Claudia Davidson , Jacquelyn S. Pennings , Phillip M. Mitchell

Introduction

Dorsiflexion weakness, or footdrop, is a well-described sequela of high-energy acetabular and pelvic trauma, but little data exists describing the factors related to neurologic recovery and the timeline therein. An improved understanding of these factors would facilitate prognostication, patient education, and treatment decision-making. The aim of this study was to compare neurologic recovery between acetabular and pelvic fractures, delineate factors associated with recovery, and determine the expected timeline of recovery.

Methods

A retrospective chart review was conducted at a level 1 tertiary referral center from 2000 to 2021 using CPT codes and keyword search functions to identify adult patients with neurologic injury in the setting of operative acetabular and/or pelvic ring trauma. Patients were included if they had documented, graded weakness not clearly explained by a concomitant injury (extremity or spine) following a pelvic/acetabular injury. Patients were followed to a minimum of 6 months follow-up or to neurologic recovery. Primary outcomes were the presence of motor recovery and time to initial and maximum recovery. The contributions of injury type and initial neurologic status were analyzed using logistic regression for impact on neurologic recovery.

Results

We identified 121 patients with neurologic injury and resultant footdrop in the setting of an operative pelvic ring or acetabular fracture. From this cohort, 58 patients (47.9 %) demonstrated some degree of neurologic recovery in follow-up. There was no difference in recovery when comparing injury type (pelvis vs. acetabulum). Any motor function (including flicker) at time of initial evaluation was predictive of recovery (OR 6.18, [2.00 – 19.14]; p = 0.002). Initial neurologic function also correlated with more rapid recovery in comparison to patients with initial absent neurologic function both in time to initial recovery (56 days vs 107 days; p = 0.016) and time to maximum recovery (153 days vs 241 days; p = 0.027).

Conclusions

These results highlight the relatively poor prognosis for neurologic recovery in operative pelvic and acetabular injuries. Any initial neurologic function is predictive of likelihood of neurologic recovery and correlates with a more expedient neurologic recovery. Ultimately, this enables providers to better educate patients and facilitates decisions regarding further intervention.
引言 外展无力或足下垂是高能量髋臼和骨盆创伤的一种后遗症,但很少有数据描述与神经功能恢复有关的因素及其时间表。加深对这些因素的了解将有助于预后判断、患者教育和治疗决策。本研究的目的是比较髋臼骨折和骨盆骨折的神经功能恢复情况,描述与恢复相关的因素,并确定预期的恢复时间表。方法:2000 年至 2021 年,在一家一级三级转诊中心使用 CPT 代码和关键词搜索功能进行了回顾性病历审查,以确定在髋臼和/或骨盆环创伤手术中出现神经功能损伤的成年患者。如果患者在骨盆/髋臼损伤后出现有记录的、不能明确解释为伴随损伤(四肢或脊柱)的分级无力,则将其纳入研究范围。对患者进行至少 6 个月的随访,或随访至神经功能恢复。主要结果是运动功能是否恢复,以及初始恢复时间和最大恢复时间。我们使用逻辑回归分析了损伤类型和初始神经功能状态对神经功能恢复的影响。结果 我们发现了 121 例因骨盆环或髋臼骨折而导致神经功能损伤和足下垂的患者。在这批患者中,有 58 名患者(47.9%)在随访中表现出一定程度的神经功能恢复。比较损伤类型(骨盆与髋臼),恢复情况没有差异。初次评估时的任何运动功能(包括闪烁)都可预测恢复情况(OR 6.18,[2.00 - 19.14];P = 0.002)。与初始神经功能缺失的患者相比,初始神经功能缺失的患者恢复得更快,无论是在初始恢复时间(56 天 vs 107 天;p = 0.016)还是在最大恢复时间(153 天 vs 241 天;p = 0.027)方面。任何最初的神经功能都可预测神经功能恢复的可能性,并与神经功能的快速恢复相关。最终,这将使医疗服务提供者能够更好地教育患者,并有助于做出进一步干预的决定。
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引用次数: 0
Surgical challenges in Non-combatant Evacuation Operations 非战斗人员撤离行动中的外科挑战
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-19 DOI: 10.1016/j.injury.2024.111961
Bruno de La Villéon , Alexandre Caubère , Alexis Maffert , Jérôme Planchon , Franck Albisson , Hugues de Martène , Alexandre Noël , Brice Malgras

Background

Global uncertainties have prompted nations to adopt vigilant approaches to safeguard their citizens. Recent crises have compelled Western nations to undertake evacuations, ranging from peaceful scenarios to urgent military interventions. In April 2023, Sudan descended into civil war, prompting France to orchestrate a complex evacuation operation leveraging prepositioned forces in Djibouti.

Materials & Methods

This retrospective observational study aims to analyze the surgical challenges encountered during Operation SAGITTAIRE (OS), focusing on human, technical, and logistical requirements for successful military interventions in multinational civilian populations.

Results

OS successfully evacuated 1017 individuals of 84 nationalities from Khartoum using road, sea, and air routes. Special forces teams, including the Surgical Life-saving Module (SLM), were mobilized alongside conventional military elements. The Joint Medical Surgical Center (JMSC) in Djibouti served as a permanent medical facility with comprehensive facilities and staff. Air Medical evacuations were performed for vicitms and surgical interventions were conducted, including damage control surgery, orthopedic procedures, and debridements. Five surgical evaluations and four surgical procedures were performed. The operation spanned 96 h without death. The SLM, deployed in Khartoum and within an aircraft, played a crucial role.

Discussion

OS highlighted the need for a comprehensive health support system. Challenges in assessing health needs led to the establishment of a substantial and adaptable system. The report emphasizes the importance of a comprehensive approach to support Non-combatant Evacuation Operations in French Doctrine.

Conclusion

OS showcased the French Health Military Service's capabilities in deploying a comprehensive damage control chain in challenging environments. This fatality-free success underlines the effectiveness of coordinated resuscitation, damage control, and transportation. Evacuation operations in non-combatant settings during civil wars pose formidable challenges, requiring a modular and adaptable support concept. Coordination, communication, logistical preparation, and training are crucial elements for successful management of such operations.
背景全球的不确定性促使各国提高警惕,以保护本国公民的安全。最近发生的危机迫使西方国家采取撤离行动,从和平方案到紧急军事干预,不一而足。2023 年 4 月,苏丹陷入内战,促使法国利用在吉布提预先部署的部队精心策划了一次复杂的撤离行动。材料与amp; 方法这项回顾性观察研究旨在分析 "萨吉泰尔行动"(OS)期间遇到的外科挑战,重点关注在多国平民人口中成功实施军事干预所需的人力、技术和后勤要求。特种部队小组,包括外科救生单元(SLM),与常规军事人员一同出动。吉布提的联合医疗外科中心(JMSC)是一个常设医疗机构,拥有完善的设施和工作人员。对受害者进行了空中医疗后送,并进行了外科手术,包括损伤控制手术、整形外科手术和清创术。共进行了五次外科评估和四次外科手术。手术历时 96 小时,无人员死亡。部署在喀土穆和一架飞机上的苏丹解放运动发挥了关键作用。在评估医疗需求方面遇到的挑战促使建立了一个实质性的、适应性强的系统。报告强调了在法国理论中采用综合方法支持非战斗人员撤离行动的重要性。结论OS 展示了法国卫生军事部门在充满挑战的环境中部署综合损害控制链的能力。这次无人员死亡的成功突显了协调复苏、损害控制和运输的有效性。内战期间,非战斗环境下的撤离行动面临严峻挑战,需要模块化和适应性强的支持理念。协调、沟通、后勤准备和培训是成功管理此类行动的关键要素。
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引用次数: 0
Fracture patterns in bicycle accidents: A descriptive national cohort study of fractures sustained in bicycle accidents in the Swedish Fracture Register 2015–2022 自行车事故中的骨折模式:2015-2022年瑞典骨折登记册中关于自行车事故中骨折的描述性全国队列研究。
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111960
Sofie Josefsson , Anders Brüggemann , Olof Wolf , Hans Peter Bögl

Introduction

Bicycle accidents account for the majority of traffic-related accidents in Sweden. Despite the widespread everyday use of bicycles, little is known about the fracture panorama resulting from bicycle accidents. This study analysed the fracture patterns of bicycle accidents in Sweden in regard to fracture type, sex, age, and type of bicycle.

Material and methods

We retrieved data from the Swedish Fracture Register on all fractures caused by bicycle accidents between 2015 and 2022. The study population was comprised of both children and adults who had sustained one or more fractures in a bicycle accident as registered in the Swedish Fracture Register.

Results

We included 33,384 fractures (25,960 in adults and 7424 in children) in 30,815 patients, with a dominance of fractures in men. The mean age at fracture was 41.6 years (SD 23). The majority of fractures (62.7 %, n = 20,932) were sustained via a low energy mechanism. Overall, the most commonly fractured body parts were the forearm (35.2 %, n = 11,747), the hand (15.6 %, n = 5,196) and the clavicle (13.7 %, n = 4,558). In children, fractures of the forearm (56.8 %, n = 4,215) clearly dominated, followed by the hand (11.7 %, n = 868), and the humerus (11.0 %, n = 816). In adults, the top 3 fracture locations were the forearm (29.0 %, n = 7,532), the hand (16.7 %, n = 4,328), and the clavicle (15.7 %, n = 4,086). Mountain bikes and road bikes showed a fracture panorama that was very similar with a predominance of fractures to the clavicle. Fractures were more common during the warm season.

Conclusion

The main finding is that bicyclists predominantly sustained fractures of the upper limb via low energy mechanisms. The fracture panorama differed by age, sex, and type of bicycle.
导言:在瑞典,自行车事故占交通事故的大多数。尽管自行车在日常生活中被广泛使用,但人们对自行车事故造成的骨折全景却知之甚少。本研究分析了瑞典自行车事故中的骨折类型、性别、年龄和自行车类型:我们从瑞典骨折登记册中检索了2015年至2022年期间所有由自行车事故造成的骨折数据。研究对象包括在瑞典骨折登记册中登记的因自行车事故造成一处或多处骨折的儿童和成人:我们纳入了 30815 名患者中的 33384 例骨折(成人 25960 例,儿童 7424 例),其中男性骨折患者居多。骨折时的平均年龄为 41.6 岁(SD 23)。大多数骨折(62.7%,n = 20932)是通过低能量机制造成的。总体而言,最常见的骨折部位是前臂(35.2%,n = 11,747)、手(15.6%,n = 5,196)和锁骨(13.7%,n = 4,558)。在儿童中,前臂骨折(56.8%,n = 4,215 例)明显占多数,其次是手部(11.7%,n = 868 例)和肱骨(11.0%,n = 816 例)。在成人中,前臂(29.0%,n = 7,532)、手部(16.7%,n = 4,328)和锁骨(15.7%,n = 4,086)是骨折发生率最高的三个部位。山地自行车和公路自行车的骨折情况非常相似,都以锁骨骨折为主。骨折在温暖季节更为常见:主要发现是骑自行车者主要通过低能量机制造成上肢骨折。骨折全景图因年龄、性别和自行车类型而异。
{"title":"Fracture patterns in bicycle accidents: A descriptive national cohort study of fractures sustained in bicycle accidents in the Swedish Fracture Register 2015–2022","authors":"Sofie Josefsson ,&nbsp;Anders Brüggemann ,&nbsp;Olof Wolf ,&nbsp;Hans Peter Bögl","doi":"10.1016/j.injury.2024.111960","DOIUrl":"10.1016/j.injury.2024.111960","url":null,"abstract":"<div><h3>Introduction</h3><div>Bicycle accidents account for the majority of traffic-related accidents in Sweden. Despite the widespread everyday use of bicycles, little is known about the fracture panorama resulting from bicycle accidents. This study analysed the fracture patterns of bicycle accidents in Sweden in regard to fracture type, sex, age, and type of bicycle.</div></div><div><h3>Material and methods</h3><div>We retrieved data from the Swedish Fracture Register on all fractures caused by bicycle accidents between 2015 and 2022. The study population was comprised of both children and adults who had sustained one or more fractures in a bicycle accident as registered in the Swedish Fracture Register.</div></div><div><h3>Results</h3><div>We included 33,384 fractures (25,960 in adults and 7424 in children) in 30,815 patients, with a dominance of fractures in men. The mean age at fracture was 41.6 years (SD 23). The majority of fractures (62.7 %, <em>n</em> = 20,932) were sustained via a low energy mechanism. Overall, the most commonly fractured body parts were the forearm (35.2 %, <em>n</em> = 11,747), the hand (15.6 %, <em>n</em> = 5,196) and the clavicle (13.7 %, <em>n</em> = 4,558). In children, fractures of the forearm (56.8 %, <em>n</em> = 4,215) clearly dominated, followed by the hand (11.7 %, <em>n</em> = 868), and the humerus (11.0 %, <em>n</em> = 816). In adults, the top 3 fracture locations were the forearm (29.0 %, <em>n</em> = 7,532), the hand (16.7 %, <em>n</em> = 4,328), and the clavicle (15.7 %, <em>n</em> = 4,086). Mountain bikes and road bikes showed a fracture panorama that was very similar with a predominance of fractures to the clavicle. Fractures were more common during the warm season.</div></div><div><h3>Conclusion</h3><div>The main finding is that bicyclists predominantly sustained fractures of the upper limb via low energy mechanisms. The fracture panorama differed by age, sex, and type of bicycle.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"55 12","pages":"Article 111960"},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of orthogeriatric co-management with prescription frequencies of anti-osteoporotic drugs in patients with fragility fractures: An observational study with health insurance data 老年骨科共同管理与脆性骨折患者抗骨质疏松药物处方频率的关系:利用医疗保险数据进行的观察研究
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111971
Kilian Rapp , Daniel Schöne , Patrick Roigk , Clemens Becker , Andrea Jaensch , Dietrich Rothenbacher , Claudia Konnopka , Hans-Helmut König , Markus Gosch , Thomas Friess , Gisela Büchele

Background

Geriatricians are increasingly involved in the treatment of fragility fractures. In Germany, hospitals that meet specific standards for orthogeriatric co-management (OGCM) are additionally certified as 'geriatric trauma centers.' One responsibility of OGCM is the appropriate management of osteoporosis through medication. We aimed to analyse the association between prescription frequencies of anti-osteoporotic drugs in hospitals with certified OGCM, those with non-certified OGCM, and those with no OGCM at all.

Methods

Claims data from nearly 200,000 patients aged 80 and older with an incident index fracture of the humerus, forearm, hip, pelvis, or spine, were obtained from a German health insurance. Hospitals were categorized into three groups: no OGCM, with OGCM, and with certified OGCM. The outcomes were new prescriptions for specific anti-osteoporotic drugs and vitamin D within 180 days after the index fracture. Crude incidences and adjusted incidence rate ratios (IRR) were calculated.

Results

Prescription rates of specific anti-osteoporotic drugs and vitamin D increased from hospitals with no OGCM to hospitals with OGCM and were highest in hospitals with certified OGCM. This pattern was observed across all fracture types, age groups, and both men and women, except for forearm fractures. For example, in hip fractures, the IRR for prescriptions of specific anti-osteoporotic drugs in hospitals with certified OGCM compared to those with no OGCM was 2.17 (95 % CI: 1.90–2.48).

Conclusion

OGCM, especially when coupled with certification as a 'Geriatric Trauma Center,' is associated with higher prescription rates of specific anti-osteoporotic drugs and vitamin D after fragility fractures in Germany.
背景老年病科医生越来越多地参与脆性骨折的治疗。在德国,符合老年骨科共同管理(OGCM)特定标准的医院还被认证为 "老年创伤中心"。OGCM 的职责之一是通过药物对骨质疏松症进行适当管理。我们旨在分析获得 OGCM 认证的医院、未获得 OGCM 认证的医院以及未获得 OGCM 认证的医院的抗骨质疏松药物处方频率之间的关联。医院被分为三组:无 OGCM、有 OGCM 和经认证的 OGCM。研究结果为骨折发生后 180 天内的特定抗骨质疏松药物和维生素 D 的新处方。结果特定抗骨质疏松药物和维生素 D 的处方率从无 OGCM 的医院上升到有 OGCM 的医院,而在有认证 OGCM 的医院中处方率最高。除前臂骨折外,这种模式在所有骨折类型、年龄组以及男性和女性中均可观察到。例如,在髋部骨折中,与未获得 OGCM 认证的医院相比,获得 OGCM 认证的医院开具特定抗骨质疏松药物处方的 IRR 为 2.17(95 % CI:1.90-2.48)。
{"title":"Association of orthogeriatric co-management with prescription frequencies of anti-osteoporotic drugs in patients with fragility fractures: An observational study with health insurance data","authors":"Kilian Rapp ,&nbsp;Daniel Schöne ,&nbsp;Patrick Roigk ,&nbsp;Clemens Becker ,&nbsp;Andrea Jaensch ,&nbsp;Dietrich Rothenbacher ,&nbsp;Claudia Konnopka ,&nbsp;Hans-Helmut König ,&nbsp;Markus Gosch ,&nbsp;Thomas Friess ,&nbsp;Gisela Büchele","doi":"10.1016/j.injury.2024.111971","DOIUrl":"10.1016/j.injury.2024.111971","url":null,"abstract":"<div><h3>Background</h3><div>Geriatricians are increasingly involved in the treatment of fragility fractures. In Germany, hospitals that meet specific standards for orthogeriatric co-management (OGCM) are additionally certified as 'geriatric trauma centers.' One responsibility of OGCM is the appropriate management of osteoporosis through medication. We aimed to analyse the association between prescription frequencies of anti-osteoporotic drugs in hospitals with certified OGCM, those with non-certified OGCM, and those with no OGCM at all.</div></div><div><h3>Methods</h3><div>Claims data from nearly 200,000 patients aged 80 and older with an incident index fracture of the humerus, forearm, hip, pelvis, or spine, were obtained from a German health insurance. Hospitals were categorized into three groups: no OGCM, with OGCM, and with certified OGCM. The outcomes were new prescriptions for specific anti-osteoporotic drugs and vitamin D within 180 days after the index fracture. Crude incidences and adjusted incidence rate ratios (IRR) were calculated.</div></div><div><h3>Results</h3><div>Prescription rates of specific anti-osteoporotic drugs and vitamin D increased from hospitals with no OGCM to hospitals with OGCM and were highest in hospitals with certified OGCM. This pattern was observed across all fracture types, age groups, and both men and women, except for forearm fractures. For example, in hip fractures, the IRR for prescriptions of specific anti-osteoporotic drugs in hospitals with certified OGCM compared to those with no OGCM was 2.17 (95 % CI: 1.90–2.48).</div></div><div><h3>Conclusion</h3><div>OGCM, especially when coupled with certification as a 'Geriatric Trauma Center,' is associated with higher prescription rates of specific anti-osteoporotic drugs and vitamin D after fragility fractures in Germany.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"55 12","pages":"Article 111971"},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic factors of falls in hospitalized adults and elderly: An epidemiological and clinical analysis 住院成年人和老年人跌倒的预后因素:流行病学和临床分析
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111966
Maria Nathalia Silva , Yanne da Silva Camargo , Tathiane Ribeiro da Silva , Andrea M. Bernardes da Silva , Diogo Fernandes dos Santos , Douglas Eulálio Antunes

Background

Falls are known to cause injuries ranging from minor to severe, resulting in local or systemic lesions. Addressing prognostic factors associated with falls is crucial for preventing this adverse event through the implementation of patient care protocols. This study aimed to explore the epidemiological, clinical, and pharmacological prognostic factors influencing falls in adult and elderly patients, assessing the timing and impact of these factors using survival curve analysis.

Methods

A retrospective observational cohort study included 176 hospitalized patients experiencing falls, categorized into adults (<60 years) and elderly (≥60 years). Binomial tests and logistic regression assessed variable associations, while Kaplan-Meier curves and Cox proportional hazards models analyzed survival.

Results

Overall, 25.9 % of adults and 33.3 % of the elderly experienced some form of injury (minor or moderate). Patients were alone during the fall in 77.6 % of cases for those under 60, compared to 50 % for those 60 and older (p < 0.001). Falls from own height were the most common, occurring in 46.6 % of patients under 60 years and 66.7 % of elderly patients (p = 0.011). Among adults under 60, factors such as past alcohol history (p = 0.0276), falling alone (p = 0.0002), benzodiazepine use (p = 0.0001), antiarrhythmic/antihypertensive medication (p = 0.0005), and antipsychotics (p = 0.0001) were significantly associated with falls. In the elderly, significant factors included falling from one's own height (p = 0.0112), muscle weakness (p = 0.0183), gait disorders (p = 0.0443), vasodilators (p = 0.0107), antihistamines (p = 0.0003), and hypoglycemic agents (p = 0.0041). Survival curve analysis indicated women under 60 had a worse prognosis for falls compared to elderly women (p = 0.038). For the elderly, opioid use (p = 0.045) and muscle weakness (p = 0.037) represented poor prognostic factors compared to adults under 60. In Cox regression, only female sex in patients under 60 showed a higher risk (HR=1.47) compared to women over 60 (p = 0.0014). Although not significant in multivariate analysis, muscle weakness (p = 0.066) and opioid use (p = 0.0545) had proportional hazards of 1.37 and 1.12, respectively.

Conclusion

Female sex indicated poorer prognosis in <60 s, while opioids and muscle weakness were concerning for the elderly. These findings emphasize the need for tailored care protocols to stratify patient fall risk and prognosis during hospitalization and develop effective preventive strategies in healthcare.
背景:众所周知,跌倒会造成轻微至严重的伤害,导致局部或全身性病变。解决与跌倒相关的预后因素对于通过实施患者护理方案预防这种不良事件至关重要。本研究旨在探讨影响成人和老年患者跌倒的流行病学、临床和药物预后因素,并利用生存曲线分析评估这些因素的发生时间和影响:一项回顾性观察队列研究纳入了 176 名发生过跌倒的住院患者,分为成人(结果:176 名患者中有 25.9% 的人发生过跌倒)和老年人(结果:176 名患者中有 25.9% 的人发生过跌倒):总体而言,25.9%的成人和 33.3%的老年人受到了某种形式的伤害(轻度或中度)。在 60 岁以下的患者中,77.6% 的患者在跌倒时是独自一人,而在 60 岁及以上的患者中,这一比例为 50%(P < 0.001)。从自身高度跌落是最常见的情况,在 60 岁以下的患者中占 46.6%,在老年患者中占 66.7%(p = 0.011)。在 60 岁以下的成年人中,既往酗酒史(p = 0.0276)、独自跌倒(p = 0.0002)、使用苯二氮卓类药物(p = 0.0001)、抗心律失常/抗高血压药物(p = 0.0005)和抗精神病药物(p = 0.0001)等因素与跌倒有显著相关性。老年人跌倒的重要因素包括:从自身高度跌倒(p = 0.0112)、肌肉无力(p = 0.0183)、步态障碍(p = 0.0443)、血管扩张剂(p = 0.0107)、抗组胺药(p = 0.0003)和降糖药(p = 0.0041)。生存曲线分析表明,与老年妇女相比,60 岁以下妇女跌倒的预后较差(p = 0.038)。与 60 岁以下的成年人相比,老年人使用阿片类药物(p = 0.045)和肌肉无力(p = 0.037)是不良预后因素。在 Cox 回归中,与 60 岁以上女性相比,60 岁以下患者中只有女性的风险较高(HR=1.47)(p = 0.0014)。虽然在多变量分析中并不显著,但肌无力(p = 0.066)和使用阿片类药物(p = 0.0545)的比例危险度分别为 1.37 和 1.12:结论
{"title":"Prognostic factors of falls in hospitalized adults and elderly: An epidemiological and clinical analysis","authors":"Maria Nathalia Silva ,&nbsp;Yanne da Silva Camargo ,&nbsp;Tathiane Ribeiro da Silva ,&nbsp;Andrea M. Bernardes da Silva ,&nbsp;Diogo Fernandes dos Santos ,&nbsp;Douglas Eulálio Antunes","doi":"10.1016/j.injury.2024.111966","DOIUrl":"10.1016/j.injury.2024.111966","url":null,"abstract":"<div><h3>Background</h3><div>Falls are known to cause injuries ranging from minor to severe, resulting in local or systemic lesions. Addressing prognostic factors associated with falls is crucial for preventing this adverse event through the implementation of patient care protocols. This study aimed to explore the epidemiological, clinical, and pharmacological prognostic factors influencing falls in adult and elderly patients, assessing the timing and impact of these factors using survival curve analysis.</div></div><div><h3>Methods</h3><div>A retrospective observational cohort study included 176 hospitalized patients experiencing falls, categorized into adults (&lt;60 years) and elderly (≥60 years). Binomial tests and logistic regression assessed variable associations, while Kaplan-Meier curves and Cox proportional hazards models analyzed survival.</div></div><div><h3>Results</h3><div>Overall, 25.9 % of adults and 33.3 % of the elderly experienced some form of injury (minor or moderate). Patients were alone during the fall in 77.6 % of cases for those under 60, compared to 50 % for those 60 and older (<em>p</em> &lt; 0.001). Falls from own height were the most common, occurring in 46.6 % of patients under 60 years and 66.7 % of elderly patients (<em>p</em> = 0.011). Among adults under 60, factors such as past alcohol history (<em>p</em> = 0.0276), falling alone (<em>p</em> = 0.0002), benzodiazepine use (<em>p</em> = 0.0001), antiarrhythmic/antihypertensive medication (<em>p</em> = 0.0005), and antipsychotics (<em>p</em> = 0.0001) were significantly associated with falls. In the elderly, significant factors included falling from one's own height (<em>p</em> = 0.0112), muscle weakness (<em>p</em> = 0.0183), gait disorders (<em>p</em> = 0.0443), vasodilators (<em>p</em> = 0.0107), antihistamines (<em>p</em> = 0.0003), and hypoglycemic agents (<em>p</em> = 0.0041). Survival curve analysis indicated women under 60 had a worse prognosis for falls compared to elderly women (<em>p</em> = 0.038). For the elderly, opioid use (<em>p</em> = 0.045) and muscle weakness (<em>p</em> = 0.037) represented poor prognostic factors compared to adults under 60. In Cox regression, only female sex in patients under 60 showed a higher risk (HR=1.47) compared to women over 60 (<em>p</em> = 0.0014). Although not significant in multivariate analysis, muscle weakness (<em>p</em> = 0.066) and opioid use (<em>p</em> = 0.0545) had proportional hazards of 1.37 and 1.12, respectively.</div></div><div><h3>Conclusion</h3><div>Female sex indicated poorer prognosis in &lt;60 s, while opioids and muscle weakness were concerning for the elderly. These findings emphasize the need for tailored care protocols to stratify patient fall risk and prognosis during hospitalization and develop effective preventive strategies in healthcare<strong>.</strong></div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"55 12","pages":"Article 111966"},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive review of current trends in e-scooter associated injuries, associated outcomes, and effective interventions: Towards establishing sustainable prevention interventions 全面回顾电动摩托车相关伤害的当前趋势、相关结果和有效干预措施:建立可持续的预防干预措施
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111967
Sanjan Kumar , Philip Lee , Ruth Zagales , Zackary Yates , Minna Haddadi , Jacob Strouse , Tracy Zito , Adel Elkbuli

Introduction

This review aims to provide a comprehensive overview of electric-scooter (E-Scooter) injuries by evaluating the incidence, common mechanisms of injury, clinical outcomes, associated costs, and effective interventions for injury prevention.

Methods

A literature search using PubMed, Google Scholar, EMBASE, and ProQuest was performed to identify relevant articles published between July 10, 2014, and July 10, 2024. Outcomes of interest included epidemiologic trends of E-Scooter injuries, common mechanisms of injury, associated risk factors, clinical outcomes, and interventions to decrease E-Scooter injuries.

Results

A total of 41 articles were included in this study, with 39 evaluating the epidemiologic trends of e-scooter injuries, 22 the most common mechanisms of injury, 21 assessed intoxication, 15 assessed helmet usage, 33 determined patient's clinical outcomes, and 3 assessed effective interventions for decreasing the incidence of e-scooter injuries. Falls were the most common mechanism of injury; however, collisions with motor vehicles caused more severe injuries. Additionally, studies showed that up to 74 % of all E-Scooter injuries included alcohol intoxication, and over 80 % did not use a helmet leading to severe head injuries.

Conclusion

The incidence of E-Scooter related injuries rose significantly in recent years. These injuries typically result from falls and MVAs and are compounded by factors including limited helmet usage and riding while intoxicated. These contribute to the poorer clinical outcomes seen with E-Scooter injuries. However, there remains a significant paucity of literature focused on the outcomes of policies and interventions designed to reduce these injuries. Further investigation must address these gaps and discrepancies to inform future policies.
导言本综述旨在通过评估电动滑板车(E-Scooter)损伤的发生率、常见损伤机制、临床结果、相关成本以及预防损伤的有效干预措施,对电动滑板车损伤进行全面概述。方法使用PubMed、Google Scholar、EMBASE和ProQuest进行文献检索,以确定2014年7月10日至2024年7月10日期间发表的相关文章。结果本研究共收录了41篇文章,其中39篇评估了电动滑板车伤害的流行趋势,22篇评估了最常见的伤害机制,21篇评估了中毒情况,15篇评估了头盔的使用情况,33篇确定了患者的临床结果,3篇评估了降低电动滑板车伤害发生率的有效干预措施。摔倒是最常见的受伤机制;然而,与机动车辆相撞造成的伤害更为严重。此外,研究还表明,在所有电动滑板车伤害中,高达 74% 的伤害包括酒精中毒,超过 80% 的伤害没有使用头盔,导致头部严重受伤。这些伤害通常是由跌倒和车祸造成的,而头盔使用率低和醉酒骑车等因素则加剧了这些伤害。这些因素导致电动滑板车损伤的临床结果较差。然而,有关旨在减少此类伤害的政策和干预措施的结果的文献仍然非常缺乏。进一步的调查必须解决这些差距和差异,为未来的政策提供依据。
{"title":"A comprehensive review of current trends in e-scooter associated injuries, associated outcomes, and effective interventions: Towards establishing sustainable prevention interventions","authors":"Sanjan Kumar ,&nbsp;Philip Lee ,&nbsp;Ruth Zagales ,&nbsp;Zackary Yates ,&nbsp;Minna Haddadi ,&nbsp;Jacob Strouse ,&nbsp;Tracy Zito ,&nbsp;Adel Elkbuli","doi":"10.1016/j.injury.2024.111967","DOIUrl":"10.1016/j.injury.2024.111967","url":null,"abstract":"<div><h3>Introduction</h3><div>This review aims to provide a comprehensive overview of electric-scooter (E-Scooter) injuries by evaluating the incidence, common mechanisms of injury, clinical outcomes, associated costs, and effective interventions for injury prevention.</div></div><div><h3>Methods</h3><div>A literature search using PubMed, Google Scholar, EMBASE, and ProQuest was performed to identify relevant articles published between July 10, 2014, and July 10, 2024. Outcomes of interest included epidemiologic trends of E-Scooter injuries, common mechanisms of injury, associated risk factors, clinical outcomes, and interventions to decrease E-Scooter injuries.</div></div><div><h3>Results</h3><div>A total of 41 articles were included in this study, with 39 evaluating the epidemiologic trends of e-scooter injuries, 22 the most common mechanisms of injury, 21 assessed intoxication, 15 assessed helmet usage, 33 determined patient's clinical outcomes, and 3 assessed effective interventions for decreasing the incidence of e-scooter injuries. Falls were the most common mechanism of injury; however, collisions with motor vehicles caused more severe injuries. Additionally, studies showed that up to 74 % of all E-Scooter injuries included alcohol intoxication, and over 80 % did not use a helmet leading to severe head injuries.</div></div><div><h3>Conclusion</h3><div>The incidence of E-Scooter related injuries rose significantly in recent years. These injuries typically result from falls and MVAs and are compounded by factors including limited helmet usage and riding while intoxicated. These contribute to the poorer clinical outcomes seen with E-Scooter injuries. However, there remains a significant paucity of literature focused on the outcomes of policies and interventions designed to reduce these injuries. Further investigation must address these gaps and discrepancies to inform future policies.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"55 12","pages":"Article 111967"},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison between nail-plate constructs and the plate-on-plate technique in the treatment of proximal femoral peri-implant fracture 在治疗股骨近端假体周围骨折时比较钉-板结构和板-板技术
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111972
Yu-Chun Chuang , Yen-Chun Chiu , Chin-Hsien Wu , Kun-Ling Tsai , I-Ming Jou , Yuan-Kun Tu , Ching-Hou Ma

Study design

A single-centre, retrospective cohort study.

Objectives

To compare the clinical outcomes between nail-plate constructs and the plate-on-plate technique in the treatment of proximal femoral peri-implant fracture (PFPIF).

Methods

Thirty-seven patients with PFPIF treated at our hospital were included. All patients underwent at least 1-year follow-up. Imaging studies and medical records, including walking ability, complications, and functional outcomes 1 year after surgery, were thoroughly reviewed.

Results

Twenty patients were treated with nail-plate constructs. Seventeen patients were treated with the plate-on-plate technique. The average surgical times in the plate-on-plate technique and nail-plate construct groups were 119.4 ± 23.4 min and 246.3 ± 48.0 min, respectively. The average blood losses in the plate-on-plate technique and nail-plate construct groups were 124.7 ± 41.6 mL and 434.3 ± 170.8 mL, respectively. The plate-on-plate technique group had a significantly shorter surgical time and less blood loss than the nail-plate construct group. No statistically significant differences were found in union time, ambulation status, 36-item Short Form Health Survey score, and complication rate between the two groups.

Conclusion

The plate-on-plate technique can be considered an alternative option to reduce operation time and blood loss in the treatment of PFPIF, especially for older patients and those who are less capable of sustaining long-term operation and anaesthetic exposure.
研究设计一项单中心、回顾性队列研究。目的比较钉-钢板结构和钢板-钢板技术在治疗股骨近端假体周围骨折(PFPIF)中的临床疗效。方法纳入本院治疗的 37 例 PFPIF 患者。所有患者均接受了至少 1 年的随访。对影像学检查和病历(包括行走能力、并发症和术后 1 年的功能结果)进行了全面审查。17名患者采用了板对板技术。板上技术组和钉板结构组的平均手术时间分别为 119.4 ± 23.4 分钟和 246.3 ± 48.0 分钟。钢板上技术组和钉板构造组的平均失血量分别为(124.7 ± 41.6)毫升和(434.3 ± 170.8)毫升。与钉板结构组相比,板上技术组的手术时间明显更短,失血量也更少。结论 在治疗 PFPIF 时,板上钉技术可被视为减少手术时间和失血量的另一种选择,尤其是对于老年患者和无法承受长期手术和麻醉的患者。
{"title":"A comparison between nail-plate constructs and the plate-on-plate technique in the treatment of proximal femoral peri-implant fracture","authors":"Yu-Chun Chuang ,&nbsp;Yen-Chun Chiu ,&nbsp;Chin-Hsien Wu ,&nbsp;Kun-Ling Tsai ,&nbsp;I-Ming Jou ,&nbsp;Yuan-Kun Tu ,&nbsp;Ching-Hou Ma","doi":"10.1016/j.injury.2024.111972","DOIUrl":"10.1016/j.injury.2024.111972","url":null,"abstract":"<div><h3>Study design</h3><div>A single-centre, retrospective cohort study.</div></div><div><h3>Objectives</h3><div>To compare the clinical outcomes between nail-plate constructs and the plate-on-plate technique in the treatment of proximal femoral peri-implant fracture (PFPIF).</div></div><div><h3>Methods</h3><div>Thirty-seven patients with PFPIF treated at our hospital were included. All patients underwent at least 1-year follow-up. Imaging studies and medical records, including walking ability, complications, and functional outcomes 1 year after surgery, were thoroughly reviewed.</div></div><div><h3>Results</h3><div>Twenty patients were treated with nail-plate constructs. Seventeen patients were treated with the plate-on-plate technique. The average surgical times in the plate-on-plate technique and nail-plate construct groups were 119.4 ± 23.4 min and 246.3 ± 48.0 min, respectively. The average blood losses in the plate-on-plate technique and nail-plate construct groups were 124.7 ± 41.6 mL and 434.3 ± 170.8 mL, respectively. The plate-on-plate technique group had a significantly shorter surgical time and less blood loss than the nail-plate construct group. No statistically significant differences were found in union time, ambulation status, 36-item Short Form Health Survey score, and complication rate between the two groups.</div></div><div><h3>Conclusion</h3><div>The plate-on-plate technique can be considered an alternative option to reduce operation time and blood loss in the treatment of PFPIF, especially for older patients and those who are less capable of sustaining long-term operation and anaesthetic exposure.</div></div>","PeriodicalId":54978,"journal":{"name":"Injury-International Journal of the Care of the Injured","volume":"55 12","pages":"Article 111972"},"PeriodicalIF":2.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No difference in early outcomes comparing intramedullary versus extramedullary fibular fixation in operative ankle fractures 腓骨髓内固定与腓骨髓外固定在踝关节骨折手术早期疗效上无差异
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111973
Kyle Auger, Ian S. Hong, McKenzie A. Mayer, Pasquale Gencarelli Jr., Conner J. Robbins, Jaclyn M. Jankowski, Frank A. Liporace, Richard S. Yoon
<div><h3>Introduction</h3><div>The purpose of this study was to compare postoperative complications and outcomes of minimally invasive intramedullary fixation (IMF) versus plate fixation (PF) in the treatment of distal fibular fractures.</div></div><div><h3>Materials and methods</h3><div>A retrospective review was performed from identifying all consecutive ankle fracture patients aged ≥18-years-old surgically managed between August 2017 to September 2022 at a tertiary care center with minimum 6 months clinical follow-up. Patients were grouped into those receiving intramedullary versus extramedullary fibular fixation. The primary outcomes were relevant demographic factors (diabetes, osteoporosis, charlson comorbidity index [CCI]), surgical time, complication rates, reoperation rates. Secondary outcomes included time to definitive fracture fixation, fracture characteristics (AO/OTA and Lauge-Hansen classification), syndesmotic instability requiring fixation and discharge disposition.</div></div><div><h3>Results</h3><div>Forty-one IMF patients (average age 55.3 ± 18.1yrs) and 162 PF patients (47.7 ± 17.4yrs) were identified and included in this study. Within the IMF group, 25 patients received IM nailing and 16 patients received percutaneous screw fixation. A greater proportion of IMF patients had diabetes (39 % vs 22 %, p < 0.001), osteoporosis (22 % vs 3 %, p < 0.001), and moderate or severe CCI (41 % vs 23 %, p = 0.017). Surgical time was significantly reduced when using IMF technique (80.4 ± 43.1 min vs 99.1 ± 43.1 min, p = 0.012). Overall complication rates or time to complication did not differ significantly between groups (p = 0.578 and p = 0.082, respectively); however, when sub-stratified, IMF patients trended towards experiencing fewer wound related complications versus PF patients (5 % vs 9 %, p = 0.291). No IMF patients experienced deep or superficial infections and only 2 (5 %) patients experienced wound dehiscence. Reoperation rates(15 % vs 10 %, p = 0.267) and time to fracture union (2.7 ± 2.2 mos vs 3.1 ± 2.0 mos, p = 0.301) did not differ significantly. At final follow-up (IMF: 15.0 ± 12.2 mos vs PF: 28.5 ± 19.5 mos), Olerud and Molander ankle score was significantly higher in IMF compared to PF (87.1 ± 14.2 vs 76.2 ± 22.6, p = 0.002).</div></div><div><h3>Conclusion</h3><div>Patients in the IMF group at baseline had several comorbid medical conditions that put them at high risk for wound related complications, however, postoperatively they demonstrated higher functional scores and similar complication rates compared to the PF group. It is important to note, however, while we expected a higher rate of wound issues with the PF group, there were no significant differences in infection rates. Either IMF and PF is reliable for fixation and outcomes, and thus with proper soft tissue, biologically friendly technique, either IMF or PF is a reliable choice in the fixation of fibula fractures.</div></div><div><h3>Level of evidence</h3><
导读:本研究旨在比较微创髓内固定(IMF)与钢板固定(PF)治疗腓骨远端骨折的术后并发症和疗效。材料和方法回顾性审查了2017年8月至2022年9月期间在一家三级医疗中心接受手术治疗且临床随访至少6个月的所有年龄≥18岁的连续踝关节骨折患者。患者被分为接受髓内固定和髓外腓骨固定的两组。主要结果包括相关人口统计学因素(糖尿病、骨质疏松症、查尔森合并症指数[CCI])、手术时间、并发症发生率、再次手术率。次要结果包括明确骨折固定的时间、骨折特征(AO/OTA 和 Lauge-Hansen 分级)、需要固定的联合韧带不稳定性和出院处置。在 IMF 组中,25 名患者接受了 IM 钉固定,16 名患者接受了经皮螺钉固定。更多的 IMF 患者患有糖尿病(39% 对 22%,P < 0.001)、骨质疏松症(22% 对 3%,P < 0.001)和中度或重度 CCI(41% 对 23%,P = 0.017)。使用 IMF 技术时,手术时间明显缩短(80.4 ± 43.1 分钟 vs 99.1 ± 43.1 分钟,p = 0.012)。各组之间的总体并发症发生率或并发症发生时间无明显差异(分别为 p = 0.578 和 p = 0.082);但如果进行细分,IMF 患者与 PF 患者相比,伤口相关并发症发生率呈下降趋势(5% vs 9%,p = 0.291)。没有 IMF 患者出现深部或表皮感染,只有 2 例(5%)患者出现伤口开裂。再手术率(15% vs 10%,p = 0.267)和骨折愈合时间(2.7 ± 2.2 个月 vs 3.1 ± 2.0 个月,p = 0.301)没有显著差异。最终随访时(IMF:15.0 ± 12.2 个月 vs PF:28.5 ± 19.5 个月),IMF 的 Olerud 和 Molander 踝关节评分明显高于 PF(87.1 ± 14.2 vs 76.2 ± 22.6,p = 0.002)。值得注意的是,虽然我们预计 PF 组的伤口问题发生率较高,但感染率并无明显差异。无论是IMF还是PF,其固定效果和预后都是可靠的,因此,如果采用适当的软组织、生物友好型技术,IMF或PF都是固定腓骨骨折的可靠选择。
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引用次数: 0
VTE rates and risk factors in major trauma patients 重大创伤患者的 VTE 发生率和风险因素
IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Pub Date : 2024-10-18 DOI: 10.1016/j.injury.2024.111964
Bibi Bassa , Elizabeth Little , David Ryan , John Cronin , Frank Lyons , Fionnuala Ni Ainle , Tomas Breslin

Background

Venous thromboembolism (VTE) is a common and in some instances life-threatening complication following severe traumatic injury. Owing to a lack of high-quality evidence in VTE risk prediction and prevention in this cohort, major trauma patients receive variable VTE preventative care. The aim of this systematic review was to determine the reported rates of VTE in major trauma patients, and associated risk factors.

Methods

A comprehensive database search was conducted using EBSCO/MEDLINE, EMBASE, CINAHL, Cochrane and Scopus to identify studies published between 1990 and 2023. Original Studies quantifying the occurrence of and/or evaluating risk factors for VTE, PE and DVT in a defined population were eligible for inclusion. Five reviewers screened, appraised, and extracted data from the selected studies.

Results

A total of 22 studies fulfilled the inclusion criteria. Most studies were conducted in Northern America (72 %), followed by Asia (18 %), and Europe (9 %). Of the 22 studies, 17 were retrospective, 4 were prospective and 1 was the control arm of an RCT. The reported rates in included studies ranged from 0.39 % to 32 % (VTE), 0.59 % to 57.60 % (DVT) and 0.35 % to 24.0 % (PE). Operative procedure was the most consistently reported associated variable for DVT followed by delays to prophylaxis and pelvic injury. Lower extremity injury was the most frequently reported associated variable for PE followed by male sex and increased age. Age was the most frequently reported variable for both DVT and PE.

Conclusion

There exists significant variation in the reported rates of VTE in major trauma patients globally. Operative procedure, delays to prophylaxis and pelvic injury were the most consistently reported associated variables for DVT. Lower extremity injury followed by male sex and increased age were the most frequently reported associated variables for PE. Although studies indicate possible differences in risk factors for DVT and PE, heterogeneity in study characteristics and outcome reporting impedes any meaningful conclusions. Reconciliation of VTE rates in major trauma patients is necessary when comparing populations.
背景静脉血栓栓塞症(VTE)是严重创伤后常见的并发症,有时甚至危及生命。由于缺乏有关 VTE 风险预测和预防的高质量证据,重大创伤患者接受的 VTE 预防护理各不相同。本系统综述旨在确定重大创伤患者中 VTE 的报告发生率及相关风险因素。方法:使用 EBSCO/MEDLINE、EMBASE、CINAHL、Cochrane 和 Scopus 进行了全面的数据库检索,以确定 1990 年至 2023 年间发表的研究。对特定人群中发生 VTE、PE 和 DVT 的风险因素进行量化和/或评估的原始研究符合纳入条件。共有 22 项研究符合纳入标准。大多数研究在北美洲进行(72%),其次是亚洲(18%)和欧洲(9%)。在这 22 项研究中,17 项为回顾性研究,4 项为前瞻性研究,1 项为研究性临床试验的对照组。纳入研究的报告率介于 0.39 % 至 32 %(VTE)、0.59 % 至 57.60 %(DVT)和 0.35 % 至 24.0 %(PE)之间。据报道,手术过程是导致深静脉血栓形成最常见的相关变量,其次是预防延误和骨盆损伤。下肢损伤是最常报告的 PE 相关变量,其次是男性和年龄增长。结论全球报告的重大创伤患者 VTE 发生率存在显著差异。手术过程、预防延误和骨盆损伤是与深静脉血栓相关的最常见变量。下肢损伤、男性和年龄增长是最常报告的 PE 相关变量。尽管研究表明深静脉血栓形成和 PE 的风险因素可能存在差异,但研究特点和结果报告的异质性妨碍了得出有意义的结论。在对人群进行比较时,有必要对重大创伤患者的 VTE 发生率进行核对。
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引用次数: 0
期刊
Injury-International Journal of the Care of the Injured
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