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Characterization of Meloidogyne enterolobii intercepted from baobab (Adansonia digitata L.) seedlings from Thailand during Japanese import plant quarantine inspection. 日本进口植物检疫检验期间从泰国猴面包树(Adansonia digitata L.)幼苗中截获的肠道黑僵菌的特征。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0027
S Sekimoto, T Inaba

In April 2019, baobab (Adansonia digitata L.) seedlings from Thailand, exhibiting galls on the roots, were intercepted during an import plant quarantine inspection at Chubu Centrair International Airport, Japan. Root-knot nematodes (RKNs) were extracted from the galled roots of baobab seedlings and identified by morphological, morphometrical and molecular methods as the guava root-knot nematode, Meloidogyne enterolobii Yang & Eisenback. The morphology and morphometrics of the intercepted population were similar to those of the original and subsequent descriptions of M. enterolobii. The sequences of D2-D3 of 28S rRNA, mtDNA intergenic COII-16S rRNA and COI genes obtained in this study matched well (99-100% similarity) with each of the gene sequences of M. enterolobii deposited in GenBank. Phylogenetic analysis of these genes revealed that the intercepted population clustered with M. enterolobii and clearly differed from other RKN species. To the best of our knowledge, this is the first report of M. enterolobii from baobab.

2019年4月,日本中部Centrair国际机场在一次进口植物检疫检查中截获了来自泰国的猴面包树(Adansonia digitata L.)幼苗,其根部出现虫瘿。从猴面包树幼苗有虫瘿的根部提取了根结线虫(RKNs),并通过形态学、形态计量学和分子学方法鉴定为番石榴根结线虫 Meloidogyne enterolobii Yang & Eisenback。截获种群的形态和形态计量学特征与最初和后来对 M. enterolobii 的描述相似。本研究获得的 28S rRNA、mtDNA 基因间 COII-16S rRNA 和 COI 基因的 D2-D3 序列与 GenBank 中保存的 M. enterolobii 各基因序列吻合良好(相似度为 99-100%)。这些基因的系统进化分析表明,截获的种群与 M. enterolobii 聚类,与其他 RKN 物种明显不同。据我们所知,这是第一份关于猴面包树肠杆菌的报告。
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引用次数: 0
Trematode parasites as indicators of an animal component in the diet of the Water Vole Arvicola amphibius. 作为水田鼠(Arvicola amphibius)食物中动物成分指标的吸虫寄生虫。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0026
A M McCarthy, J C Litten-Brown, M A Collins

The intestinal trematode fauna of the Water Vole Arvicola amphibius, (previously A. terrestris), was investigated to determine whether it might provide evidence of an animal component in the diet of this aquatic herbivorous small mammal. Interrogation of the electronic Host-Parasite Database of the Natural History Museum London revealed the presence of fourteen species of intestinal trematode in water voles, infection with each of which would require the ingestion of tissue from an animal intermediate host. The results obtained using these parasite indicators provide convincing evidence of animal components in the diet of A. amphibius and support anecdotal reports of water voles feeding on animal material in the field.

研究人员对水田鼠 Arvicola amphibius(以前为 A. terrestris)的肠道吸虫动物群进行了调查,以确定是否有证据表明这种水生草食性小型哺乳动物的食物中含有动物成分。通过查询伦敦自然历史博物馆的电子宿主-寄生虫数据库,发现水田鼠体内存在 14 种肠道吸虫,感染每一种吸虫都需要摄取动物中间宿主的组织。利用这些寄生虫指标得出的结果提供了令人信服的证据,证明两栖田鼠的食物中有动物成分,并证实了田鼠在野外取食动物材料的传闻。
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引用次数: 0
Bursaphelenchus mucronatus (Nematoda: Parasitaphelenchidae) associated with Monochamus galloprovincialis from Bosnia and Herzegovina and Georgia. 与波斯尼亚和黑塞哥维那以及格鲁吉亚的Monochamus galloprovincialis相关的Bursaphelenchus mucronatus(线虫纲:寄生虫)。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0029
V Čermák, B Nježić, N Nazarashvili, E Gvritishvili, K Tománková, H Orságová, M Majeská, J Foit, P Vieira

Bursaphelenchus mucronatus was detected in association with the pine sawyer beetle (Monochamus galloprovincialis) during the implementation and testing of cross traps with insect attractants as an efficient tool for detection survey for pine wood nematode (Bursaphelenchus xylophilus) in Bosnia and Herzegovina and Georgia in 2017 and 2018, respectively. This nematode was characterized by morphological, morphometric and molecular features. This is the first report of B. mucronatus in association with a M. galloprovincialis in Bosnia and Herzegovina and in Georgia.

2017 年和 2018 年,在波斯尼亚和黑塞哥维那以及格鲁吉亚分别实施和测试了带昆虫引诱剂的交叉诱捕器,将其作为检测调查松材线虫(Bursaphelenchus xylophilus)的有效工具,在此过程中发现了与松材线虫(Monochamus galloprovincialis)伴生的 Bursaphelenchus mucronatus。该线虫的特征包括形态、形态计量学和分子特征。这是波斯尼亚和黑塞哥维那以及格鲁吉亚首次报告 B. mucronatus 与 M. galloprovincialis 伴生的情况。
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引用次数: 0
Serological and molecular detection of neurocysticercosis among epileptic patients in Nagpur, Maharashtra state (India). 印度马哈拉施特拉邦那格浦尔癫痫患者神经囊虫病的血清学和分子检测。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0023
K Satyaprakash, W A Khan, N N Zade, S P Chaudhari, S V Shinde, N V Kurkure, P K Shembalkar

Neurocysticercosis (NCC), one of the most important neuroparasitic diseases in humans, is caused by Cysticercus cellulosae, the metacestode stage of digenetic zoonotic cestode Taenia solium. The present study aims at the detection of anti-cysticercus antibodies in the sera of epileptic patients (n=26) visiting a tertiary care hospital in Nagpur, Maharashtra state, India, by an in-house developed indirect IgG-ELISA and enzyme-linked immunoelectro transfer blot (EITB) assay using different antigens (namely, Whole Cyst Antigen (WCA), Cystic Fluid Antigen (CFA), Scolex Antigen (SA), Excretory-Secretory Antigen (ESA) and Membrane-Body Antigen (MBA)) prepared from T. solium metacestodes to find out the status of NCC. An attempt has also been made for molecular detection of NCC from blood samples of those patients by Polymerase Chain Reaction (PCR) assay targeted at large subunit rRNA gene of T. solium. The IgG ELISA level of anti-cysticercus antibodies against WCA, CFA, SA, ESA and MBA antigens were as follows: 19.23 %, 23.07 %, 38.46 %, 30.76 % and 15.38 %. The seroreactivity to CFA, SA and ESA was found in equal proportions in patients with ring-enhancing lesions. In the EITB assay, the lower and medium molecular weight protein bands of SA and ESA were immunodominant compared to the higher WCA and CFA peptides. PCR positivity could be observed in 34.6 % (9/26) of the patients under study. It is the first report of detecting NCC among epileptic patients of the Nagpur region of Maharashtra state in India using serological and molecular tools.

神经囊尾蚴病(NCC)是人类最重要的神经寄生虫病之一,由纤维囊尾蚴引起,纤维囊尾蚴是人畜共患绦虫Taenia solium的元绦虫阶段。本研究旨在检测在印度马哈拉施特拉邦那格浦尔一家三甲医院就诊的癫痫患者(26 人)血清中的抗囊尾蚴抗体、采用内部开发的间接 IgG-ELISA 和酶联免疫电泳印迹(EITB)检测法,使用从 T. solium 元胞中制备的不同抗原(即全囊抗原(WCA)、囊液抗原(CFA)、鞘膜抗原(SA)、排泄-分泌抗原(ESA)和膜-体抗原(MBA)),检测癫痫患者血清(n=26)中的抗囊虫抗体。还尝试进行了分子生物学分析,以了解 NCC 的状况。此外,还尝试通过聚合酶链式反应 (PCR) 方法从这些患者的血液样本中检测梭形虫大亚基 rRNA 基因的 NCC 分子。针对 WCA、CFA、SA、ESA 和 MBA 抗原的抗囊尾蚴抗体的 IgG ELISA 水平如下:分别为 19.23 %、23.07 %、38.46 %、30.76 % 和 15.38 %。在有环状增强病变的患者中,CFA、SA 和 ESA 的血清反应性比例相同。在 EITB 检测中,与较高的 WCA 和 CFA 肽相比,SA 和 ESA 的中低分子量蛋白带具有免疫优势。研究中,34.6%(9/26)的患者可观察到 PCR 阳性。这是利用血清学和分子工具检测印度马哈拉施特拉邦那格浦尔地区癫痫患者中 NCC 的首份报告。
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引用次数: 0
Systematic position of the enigmatic Quentinia mesovitellinica (Rêgo, 1967) (Cestoda, Cyclophyllidea). 神秘的 Quentinia mesovitellinica(Rêgo,1967 年)(绦虫纲,环叶目)的系统位置。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0031
V Haukisalmi

The systematic position of Quentinia mesovitellinica (Rêgo, 1967) (Cestoda, Cyclophyllidea) from the hystricomorph rodent Galea spixii (Wagler) (Caviidae) in Brazil is reevaluated based on published information. Quentinia mesovitellinica is generally thought to belong to the family Catenotaeniidae, being thus the only catenotaeniid cestode parasitizing hystricomorph rodents and also the only catenotaeniid in South America. However, the present study shows that Q. mesovitellinica differs fundamentally from Catenotaenia Janicki, 1904 sensu lato and other catenotaeniids with respect to several morphologic features, but shares these features with Monoecocestus Beddard, 1914 sensu Beveridge (1994), a genus in the family Anoplocephalidae sensu stricto (i.e. sensu Spasskii, 1951). However, Q. mesovitellinica is not assigned here to Monoecocestus, because the latter is a morphologically heterogeneous genus and will probably be split when subjected to a comprehensive phylogenetic and taxonomic analysis. Instead, Quentinia Spasskii, 1969 is considered a valid genus in the family Anoplocephalidae s. s. The morphologically closely related Monoecocestus eljefe Haverkost & Gardner, 2010 from Galea musteloides Meyen in Bolivia is assigned to Quentinia as Q. eljefe (Haverkost & Gardner, 2010) n. comb. An amended diagnosis is provided for Quentinia.

根据已发表的资料,重新评估了来自巴西囊尾目啮齿动物 Galea spixii (Wagler)(腔肠动物科)的 Quentinia mesovitellinica(Rêgo,1967 年)(绦虫纲,Cyclophyllidea)的系统位置。一般认为,Quentinia mesovitellinica 属于 catenotaeniidae 科,因此是唯一寄生于有节啮齿动物的 catenotaeniid 绦虫,也是南美洲唯一的 catenotaeniid 绦虫。然而,本研究表明,Q. mesovitellinica 与 Catenotaenia Janicki, 1904 sensu lato 及其他 catenotaeniids 在一些形态特征上有本质区别,但与 Monoecocestus Beddard, 1914 sensu Beveridge(1994 年)有相同之处,后者是严格意义上的 Anoplocephalidae 科的一个属(即 sensu Spasskii, 1951 年)。然而,这里并没有将 Q. mesovitellinica 划归 Monoecocestus,因为后者是一个形态异质的属,在进行全面的系统发生学和分类学分析时很可能会被拆分。相反,Quentinia Spasskii, 1969 被认为是 Anoplocephalidae s. s.科中的一个有效属。形态上密切相关的来自玻利维亚 Galea musteloides Meyen 的 Monoecocestus eljefe Haverkost & Gardner, 2010 被归入 Quentinia,命名为 Q. eljefe (Haverkost & Gardner, 2010) n. comb.为Quentinia提供了修正的诊断。
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引用次数: 0
Exploring the anthelmintic activity of Olea europaea L (Olive) leaves extract and oleuropein in mice naturally infected with Aspiculuris tetraptera. 探索油橄榄叶提取物和油橄榄素对自然感染四爪蛛的小鼠的驱虫活性。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0025
M A Kamran, H S Yildirimhan, B Şenlik

Oxyuriasis, caused by the nematode Enterobius vermicularis, is one of the cosmopolitan intestinal infections of humans. Aspiculuris tetraptera commonly infects mice and it is morphologically similar to E. vermicularis. Parasitic resistance reduces the efficiency of synthetic drugs and poses economic impacts on the dairy sector, thus necessitating novel anthelmintic agents. Olea europaea L. (Olive) is a bioactive plant with potent pharmacological activities. However, its effects on oxyurids are poorly known, and no studies are currently exploring olives' anthelmintic potential. In this study, we investigated the pharmacokinetic behaviors of O. europaea leaves extract (OLE) and its phenolic compound oleuropein in mice infected with A. tetraptera, in comparison with Albendazole (ABZ), a standard drug used to treat parasitic worms. Fecal flotation method was used to identify the infestation with A. tetraptera eggs by examining the stool samples from mice. Infected animals were divided into 7 groups. 250 mg/kg, 500 mg/kg, and 1000 mg/kg doses of OLE, 5 mg/kg and 20 mg/kg doses of oleuropein, 10 mg/kg of ABZ and tap water were orally administered by gavage for 7 days during treatments. Drug efficacies and statistical differences between the treatments and controls were evaluated. Our results revealed 92.43 % efficacy of ABZ, similar to 92.19 % efficacy of 1000 mg/kg of OLE. At the same time, 250 mg/kg and 500 mg/kg concentrations of OLE remained 70.03 % and 63.18 % effective in reducing worm counts. Efficacy percentages of 5 mg/kg and 20 mg/kg of oleuropein were 9.27 % and 70.56 %, respectively. Statistical analysis of ABZ was significant compared to 1000 mg/kg of OLE, which was almost equal but insignificant. In general, our results confirm the anthelmintic potential of OLE and oleuropein against mice pinworms and open the way for targeted extraction of bioactive compounds from plants to optimize its use in human and veterinary medicine.

由蚯蚓线虫(Enterobius vermicularis)引起的牛口疮(Oxyuriasis)是世界性的人类肠道传染病之一。Aspiculuris tetraptera 通常感染小鼠,其形态与 E. vermicularis 相似。寄生虫的抗药性降低了合成药物的效率,并对乳制品行业造成经济影响,因此需要新型抗蠕虫药物。油橄榄(Olea europaea L.)是一种生物活性植物,具有强大的药理活性。然而,人们对其对氧化乐果的作用知之甚少,目前也没有研究探索橄榄的驱虫潜力。在这项研究中,我们研究了欧芹叶提取物(OLE)及其酚类化合物欧芹素在小鼠感染 A. tetraptera 后的药代动力学行为,并与用于治疗寄生虫的标准药物阿苯达唑(ABZ)进行了比较。粪便浮选法是通过检查小鼠的粪便样本来确定是否感染了四带喙甲虫卵。受感染的动物被分为 7 组。在治疗过程中,连续7天以灌胃方式口服250毫克/千克、500毫克/千克和1000毫克/千克剂量的油菜素、5毫克/千克和20毫克/千克剂量的油菜素、10毫克/千克的ABZ和自来水。评估了药效以及治疗与对照组之间的统计学差异。结果显示,ABZ的药效为92.43%,与1000毫克/千克OLE的药效92.19%相似。同时,250 毫克/千克和 500 毫克/千克浓度的 OLE 对减少虫数的有效率分别为 70.03% 和 63.18%。5毫克/千克和20毫克/千克油菜素的有效率分别为9.27%和70.56%。与 1000 毫克/千克的油菜素相比,ABZ 的统计分析结果显著,后者几乎相等,但不显著。总之,我们的研究结果证实了欧来烯酮和油菜素对小鼠蛲虫的驱虫潜力,并为有针对性地从植物中提取生物活性化合物以优化其在人类和兽医中的应用开辟了道路。
{"title":"Exploring the anthelmintic activity of <i>Olea europaea</i> L (Olive) leaves extract and oleuropein in mice naturally infected with <i>Aspiculuris tetraptera</i>.","authors":"M A Kamran, H S Yildirimhan, B Şenlik","doi":"10.2478/helm-2023-0025","DOIUrl":"10.2478/helm-2023-0025","url":null,"abstract":"<p><p>Oxyuriasis, caused by the nematode <i>Enterobius vermicularis,</i> is one of the cosmopolitan intestinal infections of humans. <i>Aspiculuris tetraptera</i> commonly infects mice and it is morphologically similar to <i>E. vermicularis</i>. Parasitic resistance reduces the efficiency of synthetic drugs and poses economic impacts on the dairy sector, thus necessitating novel anthelmintic agents. <i>Olea europaea</i> L. (Olive) is a bioactive plant with potent pharmacological activities. However, its effects on oxyurids are poorly known, and no studies are currently exploring olives' anthelmintic potential. In this study, we investigated the pharmacokinetic behaviors of <i>O. europaea</i> leaves extract (OLE) and its phenolic compound oleuropein in mice infected with <i>A. tetraptera</i>, in comparison with Albendazole (ABZ), a standard drug used to treat parasitic worms. Fecal flotation method was used to identify the infestation with <i>A. tetraptera</i> eggs by examining the stool samples from mice. Infected animals were divided into 7 groups. 250 mg/kg, 500 mg/kg, and 1000 mg/kg doses of OLE, 5 mg/kg and 20 mg/kg doses of oleuropein, 10 mg/kg of ABZ and tap water were orally administered by gavage for 7 days during treatments. Drug efficacies and statistical differences between the treatments and controls were evaluated. Our results revealed 92.43 % efficacy of ABZ, similar to 92.19 % efficacy of 1000 mg/kg of OLE. At the same time, 250 mg/kg and 500 mg/kg concentrations of OLE remained 70.03 % and 63.18 % effective in reducing worm counts. Efficacy percentages of 5 mg/kg and 20 mg/kg of oleuropein were 9.27 % and 70.56 %, respectively. Statistical analysis of ABZ was significant compared to 1000 mg/kg of OLE, which was almost equal but insignificant. In general, our results confirm the anthelmintic potential of OLE and oleuropein against mice pinworms and open the way for targeted extraction of bioactive compounds from plants to optimize its use in human and veterinary medicine.</p>","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10750239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphological and Molecular note on the identity of Mylonchulus sigmaturus Cobb, 1917 (Nematoda: Mylonchulidae) from Pakistan. 关于巴基斯坦 Mylonchulus sigmaturus Cobb, 1917(线虫纲:Mylonchulidae)身份的形态学和分子学说明。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0024
U Ishaque, E Shokoohi, I Erum, N Kazi, S Dawar

A species of predatory nematode, Mylonchulus sigmaturus Cobb, 1917, was recovered around the soil and roots of banana plants (Musa paradisiaca) from four different localities of Pakistan. The male of this species represents a new record from Pakistan. Morphological and morphometric data of the species have been contributed along with the molecular study. The phylogenetic analysis using 18S rDNA placed the Pakistani populations of M. sigmaturus with the same species in a clade with 100 posterior probabilities. The first input of 28S rDNA data placed Pakistani M. sigmaturus in a separate clade with 100 posterior probability support, however close with Prionchulus punctatus (Cobb, 1917) Andrássy, 1958 and Clarkus papillatus (Bastian, 1865) Jairajpuri, 1970.

在巴基斯坦四个不同地方的香蕉植物(Musa paradisiaca)的土壤和根部发现了一种掠食性线虫 Mylonchulus sigmaturus Cobb, 1917。该物种的雄性代表了巴基斯坦的新记录。该物种的形态学和形态计量学数据与分子研究一起进行。使用 18S rDNA 进行的系统进化分析将巴基斯坦的 M. sigmaturus 种群与同一物种放在一个支系中,后验概率为 100。首次输入的 28S rDNA 数据将巴基斯坦的 M. sigmaturus 与 Prionchulus punctatus (Cobb, 1917) Andrássy, 1958 和 Clarkus papillatus (Bastian, 1865) Jairajpuri, 1970 放在一个单独的支系中,后验概率为 100。
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引用次数: 0
First report of Rhytidodes gelatinosus (Rudolphi, 1819) Looss, 1901 (Digenea: Rhytidodidae) in an olive-ridley Turtle Lepidochelys olivacea (Eschscholtz, 1829) from Brazil. 首次报告在巴西的一只橄榄纹龟 Lepidochelys olivacea (Eschscholtz, 1829) 中发现 Rhytidodes gelatinosus (Rudolphi, 1819) Looss, 1901 (Digenea: Rhytidodidae)。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0030
J Da Cunha Fernandes, L M De Carvalho, J C Gomes Borges, J E V Parente, M R Werneck

This article reports the first occurrence of Rhytidodes gelatinosus (Rudolphi, 1819) Looss, 1901 (Digenea: Rhytidodidae) in the olive-ridley turtle Lepidochelys olivacea (Testudines: Chelonidae), in an individual found in the State of Sergipe, Brazil. Although R. gelatinosus has already been described in other species of sea turtles in the world, this is the first report of this parasite in L. olivacea. We also present a list of hosts and locations where this helminth has already been identified.

本文报告了在巴西塞尔希培州发现的橄榄海龟 Lepidochelys olivacea(海龟纲:螯虾科)个体中首次出现的 Rhytidodes gelatinosus (Rudolphi, 1819) Looss, 1901(Digenea: Rhytidodidae)。虽然 R. gelatinosus 已经在世界其他海龟物种中被描述过,但这是该寄生虫在橄榄海龟(L. olivacea)中的首次报道。我们还列出了已经发现这种蠕虫的宿主和地点。
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引用次数: 0
Prevalence and risk factors of intestinal parasitic infections among pregnant women in Taiz Governorate, Yemen: A hospital-based study. 也门塔伊兹省孕妇肠道寄生虫感染的流行率和风险因素:一项基于医院的研究。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0022
T Alharazi

Background: Intestinal parasitic infections in pregnant women have been associated with severe adverse outcomes such as anemia, low birth weight, and mother and fetus morbidity and mortality. This study aimed to determine the prevalence of intestinal parasitic infection and its associated risk factors among pregnant women in Taiz, Yemen.

Methods: A cross-sectional study was conducted between July 2022 and January 2023. Sociodemographic and other explanatory variables were obtained via face-to-face interviews using a structured questionnaire. The wet-mount and formol-ether concentration techniques were applied to identify the IPIs. Data were analyzed using SPSS, version 20, and p-values < 0.05 were considered statistically significant. An analysis of descriptive statistics and multivariate logistic regression was conducted. A p-value < 0.05 was deemed statistically significant. The study included a total of 393 pregnant women.

Results: Of the 393 pregnant women screened for intestinal parasites, 144 (36.6 %) had at least one parasite. The most common intestinal parasite was Giardia lamblia (12.2 %), followed by Ascaris lumbricoides (10.9 %), Entamoeba histolytica/dispar (7.4 %), Enterobius vermicularis (14.3 %), and Hymenolepis nana (1.8 %). Being a farmer (AOR = 2.7, 95% CI: 1.69-4.26, p = 0:003) and drinking from unsafe water wells, streams, rain, and dams (AOR = 2:6, 95% CI: 1.68-4.25, p ≤ 0:001) were significantly associated with IPIs.

Conclusion: Pregnant women in the study area still face a severe health burden due to intestinal parasitic infection. Therefore, it is recommended that health education should be improved, and safe tap water should be provided to pregnant women to reduce the incidence of IPIs.

背景:孕妇肠道寄生虫感染与贫血、低出生体重、母亲和胎儿发病率和死亡率等严重不良后果有关。本研究旨在确定也门塔伊兹孕妇肠道寄生虫感染的流行率及其相关风险因素:这项横断面研究于 2022 年 7 月至 2023 年 1 月间进行。采用结构化问卷,通过面对面访谈获得社会人口学变量和其他解释性变量。采用湿贴和甲醇-乙醚浓缩技术识别 IPI。数据使用 SPSS 20 版进行分析,P 值小于 0.05 视为具有统计学意义。进行了描述性统计分析和多变量逻辑回归分析。p 值小于 0.05 视为具有统计学意义。研究共纳入 393 名孕妇:在接受肠道寄生虫筛查的 393 名孕妇中,144 人(36.6%)至少有一种寄生虫。最常见的肠道寄生虫是蓝氏贾第鞭毛虫(12.2%),其次是蛔虫(10.9%)、组织溶解恩塔米巴虫/双球菌(7.4%)、蚯蚓肠虫(14.3%)和海门螺杆菌(1.8%)。农民(AOR = 2.7,95% CI:1.69-4.26,p = 0:003)和饮用不安全的水井、溪流、雨水和水坝的水(AOR = 2:6,95% CI:1.68-4.25,p ≤ 0:001)与 IPIs 显著相关:结论:研究地区的孕妇仍然面临着严重的肠道寄生虫感染健康负担。因此,建议加强健康教育,并为孕妇提供安全的自来水,以降低肠道寄生虫病的发病率。
{"title":"Prevalence and risk factors of intestinal parasitic infections among pregnant women in Taiz Governorate, Yemen: A hospital-based study.","authors":"T Alharazi","doi":"10.2478/helm-2023-0022","DOIUrl":"10.2478/helm-2023-0022","url":null,"abstract":"<p><strong>Background: </strong>Intestinal parasitic infections in pregnant women have been associated with severe adverse outcomes such as anemia, low birth weight, and mother and fetus morbidity and mortality. This study aimed to determine the prevalence of intestinal parasitic infection and its associated risk factors among pregnant women in Taiz, Yemen.</p><p><strong>Methods: </strong>A cross-sectional study was conducted between July 2022 and January 2023. Sociodemographic and other explanatory variables were obtained via face-to-face interviews using a structured questionnaire. The wet-mount and formol-ether concentration techniques were applied to identify the IPIs. Data were analyzed using SPSS, version 20, and p-values < 0.05 were considered statistically significant. An analysis of descriptive statistics and multivariate logistic regression was conducted. A p-value < 0.05 was deemed statistically significant. The study included a total of 393 pregnant women.</p><p><strong>Results: </strong>Of the 393 pregnant women screened for intestinal parasites, 144 (36.6 %) had at least one parasite. The most common intestinal parasite was Giardia lamblia (12.2 %), followed by <i>Ascaris lumbricoides</i> (10.9 %), <i>Entamoeba histolytica/dispar</i> (7.4 %), <i>Enterobius vermicularis</i> (14.3 %), and <i>Hymenolepis nana</i> (1.8 %). Being a farmer (AOR = 2.7, 95% CI: 1.69-4.26, p = 0:003) and drinking from unsafe water wells, streams, rain, and dams (AOR = 2:6, 95% CI: 1.68-4.25, p ≤ 0:001) were significantly associated with IPIs.</p><p><strong>Conclusion: </strong>Pregnant women in the study area still face a severe health burden due to intestinal parasitic infection. Therefore, it is recommended that health education should be improved, and safe tap water should be provided to pregnant women to reduce the incidence of IPIs.</p>","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10750245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of hepatic and pulmonary hydatidosis with albendazole and praziquantel. 用阿苯达唑和吡喹酮治疗肝肺水肿病。
IF 1 4区 生物学 Q3 Agricultural and Biological Sciences Pub Date : 2023-12-26 eCollection Date: 2023-09-01 DOI: 10.2478/helm-2023-0028
G Popova, D Vuchev, K Anichina

Conservative treatment of human hydatidosis (cystic echinococcosis) with albendazole has improved significantly the prognosis of the disease. But its therapeutic effectiveness is 30 - 70 %. There is some evidence that the effectiveness of albendazole can be enhanced by praziquantel but there is no strict recommendation for the use of praziquantel as part of long-term drug therapy for hydatidosis. The aim of the study was to evaluate the effectiveness of the combination of albendazole and praziquantel in patients with hepatic and/or pulmonary hydatidosis. A total of 20 patients (aged 12 - 70 years old) were included in the study for a 5-year period. Fourteen patients (70 %) were with hepatic hydatidosis, 4 (20 %) with pulmonary and 2 (10 %) with hepatic and pulmonary hydatidosis. They were treated with albendazole (15 mg/kg/day) and praziquantel (40 mg/kg/weekly) for 2 - 9 one-month courses. The result of the therapy was followed using imaging (abdominal ultrasound, lung radiography, computed tomography) and serology. Seventeen (85 %) out of 20 patients showed evidence of response on imaging defined as improvement or cure of hydatid cysts. Seven (35 %) of the patients with multiple cystic echinococcosis took praziquantel once a week for 6 months. Only 3 patients (15 %) with multiple hydatidosis (2 with liver and 1 with pulmonary hydatidosis) failed to respond to the therapy with both drugs. No side effects have been reported by the patients. The combination of albendazole and praziquantel seems to be an option to improve the therapeutic effectiveness of the conservative treatment of cystic echinococcosis.

使用阿苯达唑对人类包虫病(囊状棘球蚴病)进行保守治疗可明显改善疾病的预后。但其治疗效果仅为 30% - 70%。有证据表明,吡喹酮可以提高阿苯达唑的疗效,但目前还没有严格的建议将吡喹酮作为包虫病长期药物治疗的一部分。本研究旨在评估阿苯达唑和吡喹酮联合用药对肝包虫病和/或肺包虫病患者的疗效。研究共纳入了 20 名患者(12 - 70 岁),为期 5 年。其中 14 名患者(70%)患有肝包虫病,4 名患者(20%)患有肺包虫病,2 名患者(10%)患有肝肺水包虫病。他们接受了阿苯达唑(15 毫克/千克/天)和吡喹酮(40 毫克/千克/周)治疗,疗程为 2-9 个月。治疗结果通过影像学(腹部超声波、肺部 X 射线、计算机断层扫描)和血清学进行跟踪。在 20 名患者中,有 17 人(85%)在影像学上显示出反应迹象,即包虫囊肿得到改善或治愈。多囊棘球蚴病患者中有 7 人(35%)服用吡喹酮,每周一次,持续 6 个月。只有 3 名(15%)多发性包虫病患者(2 名患有肝包虫病,1 名患有肺包虫病)对两种药物的治疗均无效。患者未报告任何副作用。阿苯达唑和吡喹酮联合用药似乎是提高囊性棘球蚴病保守治疗效果的一种选择。
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Helminthologia
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