Australian Endodontic Journal最新文献

This systematic review investigates the clinical use of bioceramic materials in retrograde apicectomy, a surgical endodontic procedure aimed at managing persistent periapical pathology. The review follows the PRISMA 2020 guidelines and is registered in PROSPERO (CRD420251022135). Comprehensive searches were conducted in PubMed, Scopus, and Web of Science from January 2000 to December 2024. Studies were included if they were human clinical trials evaluating bioceramic materials in retrograde apicectomies with a minimum follow-up of 6 months. Data extraction included sample size, material type, healing outcomes, and complications. Nineteen studies met the inclusion criteria. Findings indicated that bioceramics demonstrated superior sealing ability, biocompatibility, and osteoconductive properties compared to traditional materials such as amalgam or IRM. The analysis highlights the effectiveness of mineral trioxide aggregate (MTA) and newer formulations such as bioceramic putty and premixed hydraulic silicate cements. Bioceramics are positioned as a promising standard in apical surgery, though further long-term controlled studies are warranted.

To evaluate the diagnostic performance of artificial intelligence (AI) in detecting root canal orifices using images captured with a dental operating microscope (DOM). A total of 80 human maxillary first and second molars were included in the study. After preparing traditional access cavities, root canal orifices were identified under a dental operating microscope (DOM) at 21.25× magnification. Following orifice identification, video recordings were obtained using the DOM, from which a total of 1527 frames were randomly selected for analysis. The root canal orifices in these frames were manually labelled using CranioCatch labeling software (CranioCatch, Eskişehir, Turkey). In the binary classification task, the system correctly identified 502 out of 526 root canal orifices, yielding an accuracy of 91%. The YOLO-based CNN demonstrated high accuracy and sensitivity in detecting root canal orifices from DOM images.

A 57-year-old patient with temporomandibular disorder and toothache underwent root canal treatments on teeth 42–31 by an endodontist. Despite these treatments, the patient experienced persistent pain radiating to his ears and sought evaluation by another endodontist. No notable facial or intraoral swelling nor paresthesia was observed; however, he reported difficulty with swallowing and trismus. A large periapical radiolucent lesion was identified spanning from tooth 42 to 32, and root resorptions were observed at the apices of teeth 42, 41 and 31. The initial diagnoses for teeth 42, 41, and 31 were previously treated and symptomatic apical periodontitis. Root-end surgery with biopsy was performed. One month later, the biopsy results revealed the lesion to be a carcinoma. The patient was immediately referred to a cancer centre, where a definitive diagnosis of adenoid cystic carcinoma was made. A prompt biopsy is critical for the definitive diagnosis of malignancies for timely treatment.

Through-and-through (TAT) cortical plate defects present a challenge in periapical surgery, influencing treatment outcomes. This study investigates whether guided regenerative procedures (GRPs) enhance cortical plate healing and overall success compared to non-GRP treatments in TAT lesions. A systematic search was conducted across PubMed, CINAHL Plus, Wiley Cochrane Library, and Dental and Oral Science. Studies assessing endodontically treated teeth with TAT lesions via Cone Beam Computed Tomography were included. The risk of bias was assessed using Cochrane Risk of Bias 2.0 tool and Newcastle-Ottawa Scale. Five studies met inclusion criteria, with four included in meta-analysis. No significant differences were observed in cortical plate healing (OR: 0.52, 95% CI: 0.12–2.39; p = 0.40) or treatment success (OR: 0.35, 95% CI: 0.09–1.39; p = 0.14) between GRPs and non-GRPs. Findings suggest that GRPs do not significantly improve healing in TAT lesions, highlighting the need for further studies with larger sample sizes.

This study aims to evaluate the content and quality of videos related to minimally invasive endodontics available on the YouTube platform. Twenty videos were analysed using the video information and quality index for content quality, the Global Quality Scale for educational value, the Journal of the American Medical Association benchmark for source reliability and the adapted DISCERN tool, known as the reliability score, for overall information accuracy. Data were assessed using Kolmogorov–Smirnov, Mann–Whitney U and Spearman's correlation tests. The findings indicate that low-quality videos had higher view counts, while videos of moderate quality achieved higher Global Quality Scale, reliability score and video information and quality index scores. Additionally, statistically significant positive correlations were identified among these scores. In conclusion, most online content regarding minimally invasive endodontics presents limited accuracy and reliability, and professional consultation is recommended.

This study synthesised and characterised Haloxylon-capped silver nanoparticles (Haloxylon-AgNPs) and assessed their antibacterial and antibiofilm activity against Enterococcus faecalis. The study also examined Haloxylon-AgNPs' ability to target E. faecalis biofilms in root canals. Haloxylon salicornicum extract was used to synthesise silver nanoparticles. Physiochemical characterisation of Haloxylon-AgNPs was conducted. Antimicrobial and antibiofilm activity of Haloxylon-AgNPs was studied by agar diffusion method, minimum inhibitory concentration (MIC) determination, time-kill assay, confocal laser scanning microscopy (CLSM) and qPCR for virulence gene attenuation. One hundred and twenty extracted teeth were infected with E. faecalis and treated with either Haloxylon-AgNPs, chlorhexidine, calcium hydroxide or saline. The data were analysed using a one-way ANOVA and Tukey multiple comparison test to investigate the bacterial reduction between groups (p < 0.05, significant; p < 0.001, highly significant). A significant reduction in the thickness of biofilm and expression of cylA virulence gene of Haloxylon-AgNPs treated E. faecalis was observed. No difference was observed between Haloxylon-AgNPs, chlorhexidine and calcium hydroxide in the tooth model.