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Effect of pressure duration applied after blood sample collection on ecchymosis in older patients using anticoagulants: A randomized controlled study. 采血后施加压力时间对使用抗凝剂的老年患者瘀斑的影响:一项随机对照研究。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-07 DOI: 10.1016/j.gerinurse.2026.103918
Ayla Demirtas, Tulay Basak, Damla Erdogan

Aim: Ecchymosis occurs when blood leaks into subcutaneous tissue or capillaries rupture. In older patients, adequate pressure after venipuncture may prevent it, but the optimal duration is unclear. This study evaluated the effect of applying 20 N of direct pressure for 1, 3, or 5 minutes after blood collection on ecchymosis at 24, 48, and 72 hours in older patients using oral or subcutaneous anticoagulants.

Methods: The study used a parallel-group, prospective, single-blind randomized controlled design. The study sample consisted of 164 patients hospitalized at the geriatric clinic of a city hospital. Ecchymosis development was assessed by making and recording observations at 24, 48 and 72 h after routine blood sampling. Opsite Flexigrid was used to measure the size of the ecchymosis.

Results: The mean age of the patients was 76.26±8.01 years, 50 % were women, and 56.1 % used subcutaneous anticoagulants. A statistically significant difference was found between the groups in terms of the frequency and size of ecchymoses at 24, 48, and 72 h after blood collection (24th hour: χ²=30.792, p < 0.001; 48th hour: χ²=28.698, p = 0.001; 72nd hour: χ²=26.429, p = 0.002). The incidence of ecchymoses ≥1 cm² in the control group was 14 % at all time points, and this rate was significantly higher than in all other groups (p < 0.05).

Conclusion: In geriatric patients receiving oral or subcutaneous anticoagulants but without coagulopathy, applying pressure to the venipuncture site for 5 min after blood collection reduced the development of ecchymosis.

目的:当血液渗入皮下组织或毛细血管破裂时,会发生瘀斑。在老年患者中,静脉穿刺后适当的压力可能会预防它,但最佳持续时间尚不清楚。本研究评估了口服或皮下抗凝剂的老年患者在采血后24、48和72小时对瘀斑施加20 N直接压力1、3或5分钟的效果。方法:采用平行组、前瞻性、单盲随机对照设计。研究样本包括在一家城市医院老年门诊住院的164名患者。在常规采血后24、48和72小时观察并记录瘀斑的发展情况。采用反向挠性网格法测量瘀斑的大小。结果:患者平均年龄为76.26±8.01岁,女性占50%,使用皮下抗凝剂的占56.1%。两组患者采血后24、48、72 h血斑出现频率及大小差异有统计学意义(χ²=30.792,p < 0.001; 48 h: χ²=28.698,p = 0.001; 72 h: χ²=26.429,p = 0.002)。对照组≥1 cm²瘀斑发生率为14%,显著高于其他各组(p < 0.05)。结论:在接受口服或皮下抗凝剂治疗但无凝血功能障碍的老年患者中,采血后静脉穿刺部位施加压力5分钟可减少瘀斑的发生。
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引用次数: 0
Implementing Osteoporosis Screening in a Clinical Setting: A Quality Improvement Study. 在临床环境中实施骨质疏松筛查:一项质量改进研究。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-06 DOI: 10.1016/j.gerinurse.2026.103866
Jean Genzale, Aaron Stigers, O Danny Lee

Osteoporosis (OPR) screening has declined in the United States, highlighting the need for improved practices. This QI Study addresses the undertreatment of OPR in primary care. çwas used to collect data related to fractures and osteoporosis. Thirty-nine volunteers were evaluated for osteoporosis and fracture risk using chi-square and t-tests against a comparison control group. The analysis revealed statistically significant differences (p<0.001) in the provider ordering of DEXA scans, diagnosis of osteoporosis, and vitamin supplementation compared to the control group. These findings suggest that implementing the FRAX tool as a standard screening practice can enhance osteoporosis treatment.

骨质疏松症(OPR)筛查在美国已经下降,强调需要改进的做法。本QI研究解决了初级保健中OPR治疗不足的问题。用于收集与骨折和骨质疏松症相关的数据。对39名志愿者进行骨质疏松和骨折风险评估,采用卡方检验和t检验,对照对照组。分析显示有统计学意义的差异(p
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引用次数: 0
Association of unhealthful plant-based diet and social isolation with multi-trajectories of frailty in surviving chinese older adults over a 10-year follow-up. 不健康的植物性饮食和社会隔离与10年随访中幸存的中国老年人虚弱的多重轨迹之间的关系
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-06 DOI: 10.1016/j.gerinurse.2026.103919
Yaqi Wang, Bowen Wan, Na Wei, Qingyun Lv, Xueying Xu, Jingwen Liu, Yuan He, Hairong Chang, Li Fu, Mei Lin, Yue Zhao, Xiaonan Zhang, Xiaoying Zang

Objective: To investigate individual and joint associations of unhealthful Plant-based Diet Index (uPDI) and social isolation with multi-trajectories of frailty in surviving Chinese older adults over a 10-year follow-up.

Methods: We analyzed data of 2,440 surviving older adults from 2008 to 2018 in the Chinese Longitudinal Healthy Longevity Survey. Group-Based Multi-Trajectory Modeling (GBMTM) and Logistic regression analyses were conducted to analyses data.

Results: The GBMTM identified four distinct frailty trajectories: "No Frailty STable Group," "Mild Frailty Group," "Incident IADL-Dominant Deterioration Group," and "Global Frailty Deterioration Group." The analysis revealed that both higher uPDI and social isolation quartiles were associated with the higher risk of adverse frailty trajectories. Notably, the combined higher quartiles of uPDI and social isolation further increasing the risk.

Conclusion: uPDI and social isolation were both individually and jointly associated with multi-trajectories of frailty in surviving Chinese older adults over a 10-year follow-up.

目的:通过10年的随访,研究不健康植物性饮食指数(uPDI)和社会隔离与中国幸存老年人多轨迹虚弱之间的个体和联合关系。方法:我们分析了2008年至2018年中国纵向健康寿命调查中2440名幸存老年人的数据。采用基于分组的多轨迹建模(GBMTM)和Logistic回归分析对数据进行分析。结果:GBMTM确定了四种不同的衰弱轨迹:“无衰弱稳定组”、“轻度衰弱组”、“事件性iadl显性恶化组”和“整体衰弱恶化组”。分析显示,较高的uPDI和社会隔离四分位数与较高的不利脆弱性轨迹风险相关。值得注意的是,uPDI的高四分位数加上社会孤立进一步增加了风险。结论:在为期10年的随访中,uPDI和社会隔离与中国幸存老年人的多种衰弱轨迹单独或共同相关。
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引用次数: 0
Media exposure and the trajectory of depression in older adults: An analysis based on latent variable growth models. 媒体暴露与老年人抑郁的发展轨迹:基于潜在变量增长模型的分析。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-06 DOI: 10.1016/j.gerinurse.2026.103916
Maomin Jiang, Lin Liu, Xincheng Huang, Yisong Yao, Jialiang Feng, Zengming Ma
<p><strong>Objective: </strong>This study aims to understand the developmental trajectory of media exposure and depression in the older adults Chinese population and explore the associated influencing factors. This research seeks to establish a scientific basis for preventing and treating depression in older adults.</p><p><strong>Methods: </strong>Data were sourced from the Chinese Longitudinal Aging Social Survey (CLASS) database. We selected survey data from 2016, 2018, and 2020, focusing on participants who fully completed the depression status panel and three interviews, totaling 5,496 older adults. First, demographic variables were analyzed for descriptive statistics using SPSS 27.0, and Pearson correlation analyses of media exposure, marital status, and depression were conducted at the three time points. Second, using unconditional least squares, we estimated parameters for potential change trajectories in media exposure, marital status, and depression status among older adults, excluding covariates. Finally, latent variable growth models were constructed using Mplus 8.0 to test the developmental trajectories of media exposure and depression status among older adults, and we reported cross-sectional and prospective cross-lag correlations and ran baseline-adjusted two-wave lagged regressions in both directions as sensitivity analyses.</p><p><strong>Results: </strong>The unconditional least squares analysis revealed significant differences in initial media exposure (Ψ<sub>1</sub> = 3.655) and its growth rate (Ψ<sub>2</sub> = 1.504, p < 0.001), initial marital status (Ψ<sub>1</sub> = 0.123) and its growth rate (Ψ<sub>2</sub> = 0.009, p < 0.001), as well as in initial depression levels (Ψ<sub>1</sub> = 4.852) and their growth rate (Ψ<sub>2</sub> = 2.655, p < 0.001) among older adults. The latent variable growth model indicated a negative correlation between the intercept and slope of depression (β = -0.227, p < 0.001) and media exposure (β = -0.423, p < 0.001) in older adults. Regarding demographic characteristics, age, residence, and marital status significantly influenced the initial level of depression (p < 0.001), while gender, age, education, and residence significantly affected the slope of depression levels (p < 0.05). Additionally, the regression analysis showed that the intercept of media exposure significantly influenced the depression intercept in older adults (β = -0.373, p < 0.001), and the slope of media exposure significantly affected the slope of depression (β = -0.319, p < 0.001). Cross-lag zero-order correlations were small and mixed, baseline-adjusted two-wave lagged tests yielded similarly small effects in both directions, consistent with the parallel-process growth findings.</p><p><strong>Conclusions: </strong>Over time, media exposure in the older adults gradually decreases while their level of depression gradually increases. Therefore, it is crucial for society to monitor the media exposure and depression levels of the ol
目的:了解中国老年人媒体暴露与抑郁的发展轨迹,并探讨相关影响因素。本研究旨在为预防和治疗老年人抑郁症建立科学基础。方法:数据来源于中国纵向老龄化社会调查(CLASS)数据库。我们选择了2016年、2018年和2020年的调查数据,重点关注那些完全完成抑郁状态小组和三次访谈的参与者,共计5496名老年人。首先,采用SPSS 27.0对人口学变量进行描述性统计,并在三个时间点对媒体暴露、婚姻状况和抑郁进行Pearson相关分析。其次,使用无条件最小二乘法,我们估计了老年人媒体暴露、婚姻状况和抑郁状态的潜在变化轨迹参数,排除了协变量。最后,利用Mplus 8.0构建潜在变量增长模型,检验老年人媒介暴露与抑郁状态的发展轨迹,并报道了横断面和前瞻性交叉滞后相关性,并在两个方向上进行了基线调整的双波滞后回归作为敏感性分析。结果:无条件最小二乘分析显示,老年人初始媒体暴露(Ψ1 = 3.655)及其增长率(Ψ2 = 1.504, p < 0.001)、初始婚姻状况(Ψ1 = 0.123)及其增长率(Ψ2 = 0.009, p < 0.001)、初始抑郁水平(Ψ1 = 4.852)及其增长率(Ψ2 = 2.655, p < 0.001)差异均有统计学意义。潜在变量增长模型显示,老年人抑郁的截距和斜率(β = -0.227, p < 0.001)与媒介暴露(β = -0.423, p < 0.001)呈负相关。在人口统计学特征方面,年龄、居住地和婚姻状况显著影响抑郁初始水平(p < 0.001),性别、年龄、教育程度和居住地显著影响抑郁水平斜率(p < 0.05)。此外,回归分析显示,媒介暴露截距显著影响老年人抑郁截距(β = -0.373, p < 0.001),媒介暴露斜率显著影响抑郁斜率(β = -0.319, p < 0.001)。交叉滞后零阶相关性很小且混合,基线调整后的两波滞后测试在两个方向上都产生了类似的小影响,这与平行过程增长的结果一致。结论:随着时间的推移,老年人的媒体接触逐渐减少,而他们的抑郁水平逐渐增加。因此,社会监测老年人的媒体暴露和抑郁水平,利用各种媒体形式来预防和缓解老年人的抑郁是至关重要的。例如,创建新媒体平台可以提高老年人的媒体曝光率,并保持平衡的宣传,以确保他们在媒体参与过程中公平的获取和传播信息。此外,考虑到不同老年人群体的抑郁水平不同,干预措施应专门针对那些年龄较大、生活在农村地区、没有伴侣、受教育程度较低的老年人。实施这些措施对于改善老年人抑郁症和促进健康老龄化至关重要。
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引用次数: 0
Work and leisure time dissatisfaction is a risk factor for depressive symptoms among Japanese older adults: A 2.5-year prospective cohort study. 工作和休闲时间不满是日本老年人抑郁症状的一个危险因素:一项为期2.5年的前瞻性队列研究
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-05 DOI: 10.1016/j.gerinurse.2026.103922
Kazuya Fujii, Kenji Harada, Satoshi Kurita, Masanori Morikawa, Chiharu Nishijima, Daisuke Kakita, Hiroyuki Shimada

We aimed to determine the effects of baseline (T0) satisfaction with work and leisure time activities on the onset of depressive symptoms at follow-up (T1). In this prospective study in Japan, we included 1841 older adults aged ≥ 60 years. Participants were categorized into both dissatisfied, work dissatisfied, leisure time dissatisfied, and both satisfied groups based on baseline assessement (T0). Compared with the both satisfied group, the leisure time dissatisfied, work dissatisfied, and both dissatisfied groups had higher odds ratios for the onset of depressive symptoms at follow-up (T1). In the subgroup analysis, the both dissatisfied group showed associations with depressive symptoms, regardless of sex. The work dissatisfied and leisure time dissatisfied groups showed associations with the onset of depressive symptoms in only men and women, respectively. The risk for the onset of depressive symptoms was the highest when dissatisfaction with work and leisure time activities coexisted.

我们的目的是确定基线(T0)对工作和休闲活动的满意度对随访(T1)抑郁症状发作的影响。在日本的这项前瞻性研究中,我们纳入了1841名年龄≥60岁的老年人。根据基线评估(T0),参与者被分为两组:不满意组、工作不满意组、休闲时间不满意组和两组满意组。与两者满意组相比,休闲时间不满意组、工作不满意组和两者不满意组在随访时出现抑郁症状的比值比更高(T1)。在亚组分析中,两种不满意的组都表现出抑郁症状,不分性别。工作不满意组和休闲时间不满意组分别与男性和女性出现抑郁症状有关。当对工作和休闲活动的不满意同时存在时,出现抑郁症状的风险最高。
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引用次数: 0
Exploring the professional quality of life of nursing assistants and its influencing factors: a cross-sectional study based on latent profiling. 护理助理员职业生活质量及其影响因素探讨:基于潜在分析的横断面研究。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-04 DOI: 10.1016/j.gerinurse.2026.103924
Liu Ankang, Xu Shanshan, Lv Huilan, Li Xiaodong, Xiao Hua, Lai Yingling, Yuan Shuting, Zhou Kebing, Chen Juan, Han Biyuan

Purpose: This study aimed to explore the professional quality of life among nursing assistants and identify latent profiling, and examine their relationships with perceived organizational support and self-efficacy.

Design: A cross - sectional survey study was conducted.

Methods: Nursing assistants from two hospitals in Shenzhen, China, were recruited through convenience sampling. Demographic characteristics, perceived organizational support, self-efficacy, and professional quality of life were measured using validated scales. Latent profile analysis (LPA) identified subgroups of professional quality of life, and logistic regression examined the associations of demographic factors, organizational support, and self-efficacy with profile membership.

Results: A total of 354 nursing assistants were included in this study. The professional quality of life was classified into three profiles: "adaptive group", "stress group", and "high burden group" comprising 216, 102, and 36 nursing assistants, respectively. Statistical differences were observed among the three groups in terms of demographic characteristics such as gender, ethnicity, certification, and professional title (P < 0.05). Additionally, instrumental support, emotional support, and self - efficacy differed significantly among the groups (P < 0.05). Gender (female), licensure, professional title (primary and mid - level), emotional support, and self - efficacy were predictors of nursing assistants' professional quality of life.

Conclusion: These findings may facilitate the identification of different profiles of nursing assistants for targeted training programs aimed at improving their professional quality of life. Furthermore, intervention strategies emphasizing emotional support, and self - efficacy may offer valuable approaches for enhancing professional quality of life.

目的:本研究旨在探讨护理助理的职业生活质量,识别潜在特征,并研究其与感知组织支持和自我效能的关系。设计:采用横断面调查研究。方法:采用方便抽样的方法,从深圳市两家医院招募护理员。人口统计学特征、感知组织支持、自我效能和职业生活质量采用验证的量表进行测量。潜在剖面分析(LPA)确定了职业生活质量的亚组,逻辑回归检验了人口统计学因素、组织支持和自我效能感与剖面成员的关系。结果:本研究共纳入护理员354名。将护理人员职业生活质量分为“适应组”、“压力组”和“高负担组”,分别有216名、102名和36名护理人员。三组患者在性别、种族、职称、职称等人口学特征方面差异有统计学意义(P < 0.05)。此外,工具支持、情绪支持和自我效能感组间差异有统计学意义(P < 0.05)。性别(女性)、执业资格、职称(初级和中级)、情感支持和自我效能感是护理助理职业生活质量的预测因子。结论:这些发现可能有助于识别护理助理的不同特征,为有针对性的培训计划提供帮助,旨在提高他们的职业生活质量。此外,强调情绪支持和自我效能的干预策略可能为提高职业生活质量提供有价值的途径。
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引用次数: 0
Childhood hunger experiences were associated with adverse health outcomes in older Brazilian adults: Evidence from the Brazilian Longitudinal Study of Aging (ELSI-Brazil). 童年饥饿经历与巴西老年人的不良健康结果相关:来自巴西老龄化纵向研究(ELSI-Brazil)的证据。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-04 DOI: 10.1016/j.gerinurse.2026.103815
Nair Tavares Milhem Ygnatios, Juliana Lustosa Torres, Núbia Carelli Pereira de Avelar, Luciana de Souza Braga, Taciana Muniz Rodrigues, Maria Fernanda Lima-Costa, Bruno de Souza Moreira

We aimed to assess whether childhood hunger experiences are associated with adverse health outcomes in old age. A cross-sectional study was conducted using data from the second wave of the ELSI-Brazil (2019-2021). Childhood hunger was assessed by the following question: "From birth until you were 15 years old, have you ever had a lack of food in your home and ended up going to bed feeling hungry?". Outcomes were obesity, multimorbidity, limitation in basic activities of daily living (BADLs), frailty, cognitive impairment, and depressive symptoms. Logistic regression was used in data analysis. The prevalence of childhood hunger experiences was 23.6%. After adjustments, having experienced hunger in childhood was significantly associated with higher odds of multimorbidity (OR=1.17; 95%CI=1.01-1.35), limitation in BADLs (OR=1.39; 95%CI=1.03-1.87), frailty (OR=1.35; 95%CI=1.03-1.77), and depressive symptoms (OR=1.42; 95%CI=1.15-1.76). These findings suggest the necessity for public policies to ensure adequate childhood nutrition to promote healthy aging in future generations.

我们的目的是评估儿童期饥饿经历是否与老年期不良健康结果相关。使用第二波elsi -巴西(2019-2021)的数据进行了横断面研究。儿童期饥饿感是通过以下问题来评估的:“从出生到15岁,你是否曾经在家里缺少食物,最后饿着肚子上床睡觉?”结果是肥胖、多病、基本日常生活活动受限(BADLs)、虚弱、认知障碍和抑郁症状。数据分析采用Logistic回归。儿童期饥饿经历患病率为23.6%。调整后,儿童期经历过饥饿与多病发生率(OR=1.17; 95%CI=1.01-1.35)、badl限制(OR=1.39; 95%CI=1.03-1.87)、虚弱(OR=1.35; 95%CI=1.03-1.77)和抑郁症状(OR=1.42; 95%CI=1.15-1.76)显著相关。这些发现表明,有必要制定公共政策,确保儿童营养充足,以促进后代健康老龄化。
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引用次数: 0
Use of the neuropsychiatric inventory questionnaire to assess antipsychotic prescribing practices in patients with dementia: A quality improvement project. 使用神经精神量表问卷评估痴呆患者的抗精神病药物处方实践:一个质量改进项目。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-04 DOI: 10.1016/j.gerinurse.2026.103858
Jeanne Marie Burnkrant

Strategies to ensure appropriate prescribing of antipsychotics in behavioral and psychological symptoms of dementia (BPSD) are limited in the primary care setting. In a metropolitan primary care setting, antipsychotic medications were found to be inappropriately prescribed in 45 % of patients with BPSD as defined by American Psychiatric Association (APA) clinical guidelines. A quality improvement project (QIP) was implemented to educate providers on appropriate prescribing for BPSD using the Neuropsychiatric Inventory Questionnaire (NPI-Q) tool. Outcome measures were to reduce inappropriate prescribing from 45 % to 30 % and reduce adverse events from 9 % to 4 %. At the completion of the project, results exceeded the goal with a reduction of inappropriate prescribing to 19 % and, achieved a 3 % reduction of adverse events. This project demonstrates the benefit of using the NPI-Q tool as a guideline for other primary care providers to safely establish prescribing practices for patients with BPSD.

在初级保健机构中,确保在痴呆症的行为和心理症状(BPSD)中适当开抗精神病药物处方的策略是有限的。根据美国精神病学协会(APA)临床指南的定义,在大城市的初级保健机构中,发现45%的BPSD患者的抗精神病药物是不适当的。我们实施了一项质量改进项目(QIP),利用神经精神量表问卷(NPI-Q)工具教育提供者如何适当地开具BPSD的处方。结果测量是将不适当的处方从45%减少到30%,将不良事件从9%减少到4%。在项目完成时,结果超过了目标,将不适当的处方减少了19%,不良事件减少了3%。该项目展示了使用NPI-Q工具作为其他初级保健提供者为BPSD患者安全建立处方实践指南的好处。
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引用次数: 0
Effectiveness of physical exercise on osteosarcopenia in older adults: A systematic review. 体育锻炼对老年人骨骼肌减少症的有效性:一项系统综述。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-03 DOI: 10.1016/j.gerinurse.2026.103878
Erika Aparecida Silveira, Guilherme Vinícius Elias Souza, Luciana Pereira Rodrigues, Andréa Toledo de Oliveira Rezende, Amanda Maria de Sousa Romeiro, Matias Noll, Cesar de Oliveira

Background: Osteosarcopenia is a geriatric syndrome characterized by the coexistence of sarcopenia and osteopenia/osteoporosis, which can lead to frailty and mortality. The effectiveness of physical exercise on osteosarcopenia, particularly on muscular and skeletal parameters, remains unclear. This systematic review aimed to analyze the impact of exercise interventions on osteosarcopenia in older adults and to describe the diagnostic methods used in different clinical trials.

Methods: Randomized clinical trials conducted in older adults (≥65 years) diagnosed with osteosarcopenia were included, sourced from PubMed, Embase, Cochrane, and Scopus databases without language or publication year restrictions, up to July 2024. Osteosarcopenia was defined as the coexistence of sarcopenia and osteopenia/osteoporosis based on dual-energy X-ray absorptiometry (DXA) criteria. Exercise interventions of at least four weeks were considered, with comparisons to non-exercise control groups. This systematic review followed the PRISMA guidelines and was registered in PROSPERO (CRD42016043310).

Results: A total of 250 articles were identified, but only four studies met the eligibility criteria, involving 195 participants. All included studies utilized resistance training (RT) as the exercise intervention. The most common diagnostic criteria for osteosarcopenia were based on the T-score of the lumbar spine and/or femur, measured via DXA, using World Health Organization cut-off points for bone mineral density (BMD) and the criteria from the European Working Group on Sarcopenia in Older People for sarcopenia. RT was found to be effective in increasing strength and muscle mass in older adults diagnosed with osteosarcopenia, though it did not significantly improve physical performance.

Conclusion: There are few studies on this topic, making it difficult to draw definitive conclusions regarding the effectiveness of physical exercise in older adults with osteosarcopenia. Resistance training showed positive results, particularly in improving strength and muscle mass. PROSPERO REGISTRATION NUMBER: https://www.crd.york.ac.uk/PROSPERO/view/CRD42020215659.

背景:骨骼肌减少症是一种以骨骼肌减少和骨质减少/骨质疏松共存为特征的老年综合征,可导致虚弱和死亡。体育锻炼对骨骼肌减少症的有效性,特别是对肌肉和骨骼参数的有效性尚不清楚。本系统综述旨在分析运动干预对老年人骨骼肌减少症的影响,并描述不同临床试验中使用的诊断方法。方法:纳入在诊断为骨骼肌减少症的老年人(≥65岁)中进行的随机临床试验,这些试验来自PubMed, Embase, Cochrane和Scopus数据库,没有语言或出版年份限制,截至2024年7月。根据双能x线骨密度测定(DXA)标准,骨量减少症定义为骨量减少和骨质减少/骨质疏松症共存。考虑进行至少四周的运动干预,并与不运动的对照组进行比较。该系统评价遵循PRISMA指南,并在PROSPERO注册(CRD42016043310)。结果:共纳入250篇文献,但只有4篇研究符合入选标准,共纳入195名受试者。所有纳入的研究均采用阻力训练(RT)作为运动干预。骨骼肌减少症最常见的诊断标准是基于腰椎和/或股骨的t评分,通过DXA测量,使用世界卫生组织骨密度(BMD)的分界点和欧洲老年人骨骼肌减少症工作组的标准。研究发现,RT疗法可以有效地增加被诊断为骨骼肌减少症的老年人的力量和肌肉质量,尽管它没有显著改善身体表现。结论:关于这一主题的研究很少,因此很难得出关于体育锻炼对老年人骨骼肌减少症的有效性的明确结论。阻力训练显示出积极的效果,特别是在提高力量和肌肉质量方面。普洛斯彼罗注册号:https://www.crd.york.ac.uk/PROSPERO/view/CRD42020215659。
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引用次数: 0
Unique contributions of heart failure and chronic pain on physical function and quality of life in older adults. 心力衰竭和慢性疼痛对老年人身体功能和生活质量的独特贡献。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-02-03 DOI: 10.1016/j.gerinurse.2026.103921
Asa B Smith, Anna K Forster, Katelyn E Webster-Dekker, Kelly L Wierenga

Aims: The aims of this study were to investigate if chronic pain presence is significantly increased in older adults with heart failure (HF) compared to those without HF, and if a combination of pain and HF reduced quality of life and physical function.

Methods: Retrospective cross-sectional survey and medical record data from 41,395 participants age ≥65 in the All of Us Research Program were analyzed using linear and logistic regression.

Results: Participants with HF had a higher prevalence of chronic pain than those without HF but was not statistically significant. Having pain only, HF only, and both pain and HF were associated with reduced quality of life and physical function when compared to having no HF or pain. However, these associations were the strongest in those with both chronic pain and HF.

Conclusions: A combination of HF and chronic pain markedly worsened outcomes, underscoring the need for improved pain management.

目的:本研究的目的是调查老年心力衰竭(HF)患者的慢性疼痛是否明显增加,以及疼痛和HF的结合是否会降低生活质量和身体功能。方法:采用线性和逻辑回归分析来自我们所有研究项目中年龄≥65岁的41395名参与者的回顾性横断面调查和病历资料。结果:HF患者的慢性疼痛发生率高于非HF患者,但差异无统计学意义。与无心衰或疼痛相比,仅疼痛、仅心衰以及疼痛和心衰均与生活质量和身体功能下降相关。然而,这些关联在慢性疼痛和心衰患者中最强。结论:心衰和慢性疼痛的合并明显恶化了预后,强调了改善疼痛管理的必要性。
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Geriatric Nursing
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