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Healthcare workers’ perspectives on evidence-based infection control in South Korean nursing homes: A qualitative study 韩国养老院医护人员对循证感染控制的看法:一项定性研究
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-21 DOI: 10.1016/j.gerinurse.2026.103874
Yu Mi Yi PhD , Soo Min Lee PhD , Eun-Young Noh PhD , Yeon-Hwan Park PhD
Infection prevention is critical for improving safety and care quality, reducing mortality, and enhancing the quality of life in nursing homes for older adults. These establishments often lack standardized guidelines, and have inconsistent protocols. This study evaluated the Evidence-Based Guidelines for Nursing Home Infection Control in South Korea (ENIK) by examining healthcare workers’ (HCWs) experiences. Five focus groups, involving 28 HCWs in total, were analyzed using qualitative content analysis and the Systems Engineering Initiative for Patient Safety framework. Participants reported improved infection prevention and control after ENIK implementation. Key motivators included knowledge acquisition, retraining, and positive experiences. Challenges involved staff turnover and external control factors. Clear job roles enhanced efficiency and confidence. Supportive resources (hand hygiene tools, infection control specialists, checklists, and visual aids) and organizational measures (rewards, teamwork, and control systems) were essential in streamlining infection management. ENIK fostered knowledge, clear roles, resource availability, and systematic management, enhancing infection control and care quality.
预防感染对于改善养老院的安全和护理质量、降低死亡率和提高老年人的生活质量至关重要。这些机构往往缺乏标准化的指导方针,并且有不一致的协议。本研究通过检查医护人员(HCWs)的经验,评估了韩国疗养院感染控制循证指南(ENIK)。使用定性内容分析和患者安全系统工程倡议框架对五个焦点小组进行了分析,共涉及28个卫生保健中心。参与者报告了ENIK实施后感染预防和控制的改善。主要的激励因素包括知识获取、再培训和积极的经历。挑战涉及人员流动和外部控制因素。明确的工作角色提高了效率和信心。支持性资源(手卫生工具、感染控制专家、检查清单和视觉辅助工具)和组织措施(奖励、团队合作和控制系统)对于简化感染管理至关重要。ENIK促进了知识、明确角色、资源可用性和系统管理,提高了感染控制和护理质量。
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引用次数: 0
Association between anticholinergic burden scales and recurrent falls in independently living older adults: a cross-sectional study. 独立生活的老年人抗胆碱能负荷量表与复发性跌倒之间的关系:一项横断面研究。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.1016/j.gerinurse.2026.103853
Elena Casabona PhD , Jessica Cusato PhD , Marco Clari PhD , Beatrice Albanesi PhD , Dario Cattaneo PhD , Paola Di Giulio MScN , Valerio Dimonte MScN
This study examined the association between medications with anticholinergic (ACh) activity and the risk of falls in community-dwelling older adults enrolled in a home monitoring service. A cross-sectional design was applied, and logistic regression analyses were adjusted for age, sex, comorbidities, and functional status. The sample included 84 participants who had experienced at least one fall, of whom 72.6% were single fallers and 27.4% recurrent fallers (≥2 falls in 12-months of observation). Participants were divided into two groups: those taking medications (n = 55) and those not on medication (n = 29). A total of 126 falls were reported, with no significant difference in the number of falls between the two groups.
The prevalence of ACh burden, assessed using ten different scales, ranged from 5.4% to 30.9% among fallers. Within the medication group, no significant differences were observed in the presence of ACh burden (≥1) between single and recurrent fallers. However, recurrent fallers in this group (n = 15) had higher scores on some scales compared with single fallers. Despite this, the discriminative ability of the ACh burden scales for identifying recurrent fallers were limited, with several, particularly the ALS and CrAS scales, failing to reach acceptable thresholds. After adjustment, the AAS scale suggested that older adults were over nine times more likely to experience recurrent falls compared with a single fall (OR=9.24; 95% CI 1.02–77.49; p = 0.004).
Overall, these findings highlight the limited clinical utility of current ACh burden scales in supporting medication review as part of fall prevention strategies for older adults.
本研究考察了抗胆碱能(ACh)活性药物与参加家庭监测服务的社区居住老年人跌倒风险之间的关系。采用横断面设计,并根据年龄、性别、合并症和功能状态调整逻辑回归分析。样本包括84名至少经历过一次跌倒的参与者,其中72.6%为单次跌倒者,27.4%为复发性跌倒者(12个月内观察≥2次跌倒)。参与者被分为两组:服药组(n = 55)和非服药组(n = 29)。共报告了126例跌倒,两组之间的跌倒次数没有显著差异。使用10种不同的量表评估的乙酰氨基酚负担患病率在跌倒者中从5.4%到30.9%不等。在给药组内,单次跌倒者和复发跌倒者之间乙酰胆碱负荷(≥1)的存在无显著差异。然而,该组中复发性跌倒者(n = 15)在某些量表上的得分高于单一跌倒者。尽管如此,乙酰胆碱负担量表鉴别复发性跌倒者的能力有限,有几个,特别是ALS和CrAS量表,未能达到可接受的阈值。调整后,AAS量表显示老年人复发性跌倒的可能性是单次跌倒的9倍以上(OR=9.24; 95% CI 1.02-77.49; p = 0.004)。总的来说,这些发现强调了当前乙酰胆碱负担量表在支持药物审查作为老年人跌倒预防策略的一部分方面的有限临床效用。
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引用次数: 0
Coping strategies, psychological resilience, and professional commitment among nurse-aide students in Taiwan: A cross-sectional study 台湾护生应对策略、心理弹性与专业承诺之横断面研究。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-24 DOI: 10.1016/j.gerinurse.2026.103890
Chia-Chen Chang PhD , Chen-Yin Tung PhD

Background

With rising global demand for long-term care, understanding nurse-aide students’ psychological and professional readiness is vital for effective training.

Purpose

This study explored coping strategies, psychological resilience, and professional commitment among senior nurse-aide students in Taiwan, assessing links to experiential factors to guide educational strategies.

Methods

A cross-sectional survey of 158 randomly selected senior students from Taiwan’s long-term care programs used validated tools to measure coping, resilience, and commitment. Data were analyzed with Pearson correlations, t-tests, ANOVA, and regression.

Results

Professional commitment varied significantly across professional-related training backgrounds. Students who had completed a nurse-aide internship or obtained a nurse-aide certificate demonstrated higher levels of commitment than those with no formal training. Similarly, students with long-term care work experience showed greater commitment than those without such experience. Both coping strategies and psychological resilience were positively associated with professional commitment, and together these psychological and experiential factors explained 35.1% of its variance.

Conclusions

Coping, resilience, and practical training reinforce professional commitment. Embedding these elements in long-term care education can enhance caregiving readiness and workforce sustainability in the context of global aging.
背景:随着全球对长期护理需求的增加,了解护理学生的心理和专业准备对有效培训至关重要。摘要目的:本研究探讨台湾护生应对策略、心理弹性与专业承诺之关系,探讨其与经验因素的关联,以指导教育策略。方法:采用横断面调查的方法,随机抽取158名台湾长期照护计划的高年级学生,使用有效的工具来测量他们的应对、复原力和承诺。数据分析采用Pearson相关性、t检验、方差分析和回归分析。结果:专业承诺在专业相关培训背景中存在显著差异。完成护士助理实习或获得护士助理证书的学生比没有接受过正式培训的学生表现出更高的承诺水平。同样,有长期护理工作经验的学生比没有这种经验的学生表现出更大的承诺。应对策略和心理弹性均与职业承诺呈正相关,心理和经验因素共同解释了35.1%的方差。结论:应对、弹性和实践训练增强了专业承诺。在全球老龄化背景下,将这些要素纳入长期护理教育可以提高护理准备和劳动力的可持续性。
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引用次数: 0
Current status and factors influencing analysis on readiness of hospital discharge among elderly patients following hip and knee arthroplasty under the concept of enhanced recovery after surgery: A cross-sectional study 以增强术后恢复为理念的老年髋关节置换术患者出院准备现状及影响因素分析:一项横断面研究
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-24 DOI: 10.1016/j.gerinurse.2026.103835
Yufeng Li MSc , Yun Li BSc , Shengying Wang BSc , Wenjiao Li MSc , Li Feng BSc , Zhibin Liu BSc , Yang Zhou MSc , Xiujie Sun MSc

Objectives

To identify factors affecting readiness of hospital discharge (RHD) among Chinese elderly patients after hip or knee arthroplasty under Enhanced Recovery After Surgery (ERAS).

Design

This study followed the cross-sectional descriptive design and the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) guideline.

Methods

Data from 511 elderly patients who underwent hip or knee arthroplasty in a tertiary hospital (October 2021 to August 2023) were analyzed. Participants completed demographic, the Blaylock Risk Assessment Screening Score (BRASS), the Activities of Daily Living (ADL) score, and the Readiness for Hospital Discharge Scale (RHDS) before discharge. Correlations and multiple linear regression identified factors associated with RHD.

Results

The mean RHDS score was 100.45 ± 12.44, indicating moderate to high readiness. RHDS correlated positively with ADL (r = 0.586, p < 0.001) and negatively with BRASS (r = –0.501, p < 0.001). Regression showed that ADL, BRASS, gender, age, admission form, and surgical type were independent predictors (Adjusted R² = 0.414, p < 0.001).

Conclusion/Relevance to clinical practice

Elderly patients showed moderate to high RHD, which still requires improvement. Early evaluation, tailored discharge education, and follow-up nursing interventions can enhance recovery and reduce readmission. These findings underscore the importance of strengthening discharge readiness education in geriatric nursing practice.
目的:确定影响中国老年髋关节或膝关节置换术后增强康复(ERAS)患者出院准备度(RHD)的因素。设计:本研究遵循横断面描述性设计和加强流行病学观察性研究报告(STROBE)指南。方法:对2021年10月至2023年8月在某三级医院行髋关节或膝关节置换术的511例老年患者的数据进行分析。参与者在出院前完成人口统计、Blaylock风险评估筛选评分(BRASS)、日常生活活动(ADL)评分和出院准备量表(RHDS)。相关性和多元线性回归确定了与RHD相关的因素。结果:RHDS平均评分为100.45±12.44,为中度至高度准备。RHDS与ADL呈正相关(r = 0.586, p < 0.001),与BRASS呈负相关(r = -0.501, p < 0.001)。回归分析显示,ADL、BRASS、性别、年龄、入院方式、手术类型是独立预测因素(调整后R²= 0.414,p < 0.001)。结论/与临床实践的相关性:老年患者表现为中高RHD,仍需改善。早期评估,有针对性的出院教育和后续护理干预可以提高康复和减少再入院。这些发现强调了在老年护理实践中加强出院准备教育的重要性。
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引用次数: 0
Implementing Non-Pharmacological interventions for dementia in long-term care: A scoping review 在长期护理中实施痴呆的非药物干预:范围综述。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-18 DOI: 10.1016/j.gerinurse.2026.103901
April Morris DNP , Melissa Kalarchian PhD , Angela Allen PhD
Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent among residents in long-term care (LTC) and contribute to poor quality of life and increased caregiver burden. Non-pharmacological interventions (NPIs) are recommended as first-line approaches, but their implementation is often limited by workforce shortages, inconsistent protocols, and lack of staff preparation. This scoping review mapped NPI characteristics, reported outcomes, and key implementation challenges used to address BPSD in LTC. Thirty-two studies met criteria and were included, encompassing music therapy, reminiscence therapy, exercise programs, assistive technology, multimodal interventions, and emerging therapies. Intervention characteristics such as personalization and cultural tailoring were associated with improved engagement and emotional responsiveness. Outcomes included reductions in agitation, anxiety, and mood disturbances, though effects varied across settings and modalities. Common challenges included staffing limitations, lack of standardized protocols, and ethical considerations. These findings point to opportunities for more structured, scalable NPI models and highlight the need for future research that incorporates resident and staff perspectives to support sustainable dementia care practices.
痴呆症的行为和心理症状(BPSD)在长期护理(LTC)的居民中非常普遍,并导致生活质量下降和照顾者负担增加。非药物干预措施(npi)被推荐为一线方法,但其实施往往受到劳动力短缺、协议不一致和工作人员准备不足的限制。该范围审查映射了NPI特征、报告结果和用于解决LTC中BPSD的关键实施挑战。32项研究符合标准,包括音乐疗法、回忆疗法、运动项目、辅助技术、多模式干预和新兴疗法。个性化和文化定制等干预特征与改善的参与和情绪反应有关。结果包括躁动、焦虑和情绪障碍的减少,尽管效果因环境和模式而异。常见的挑战包括人员配备限制、缺乏标准化协议和道德考虑。这些发现指出了建立更结构化、可扩展的NPI模型的机会,并强调了未来研究的必要性,这些研究将纳入住院医生和工作人员的观点,以支持可持续的痴呆症护理实践。
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引用次数: 0
Geriatrics cognitive assessment and resource engagement day: Piloting an interdisciplinary outpatient cognitive care model 老年医学认知评估和资源参与日:跨学科门诊认知护理模式的试点。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-02-02 DOI: 10.1016/j.gerinurse.2026.103923
Kanishk D. Sharma MD , Gaby Naranjo LMSW , Amy Harper OTD, OTR/L, CHT

Background

Despite high healthcare costs, people with dementia and their caregivers still struggle with care coordination and support. Centers for Medicare & Medicaid Services “Guiding an Improved Dementia Experience” initiative, presents an opportunity for innovative care models.

Methods

Authors piloted Geriatrics Cognitive Assessment and Resource Engagement (CARE) Day, an interdisciplinary clinic model for patients living with dementia. In a single visit, patients saw a geriatrician, social worker, occupational therapist, and Alzheimer’s Association care specialist.

Results

CARE Day streamlined four different appointments into one, enhancing coordination. Geriatricians conducted cognitive assessments and care planning. Social workers connected caregivers to support groups and education. Occupational therapists addressed daily function, safety, and cognitive rehab needs. Alzheimer's Association care specialists connected families to memory-friendly programs. Follow-ups showed high patient and caregiver satisfaction, improved coordination, and fewer missed appointments.

Conclusion

Interdisciplinary clinic approach improves dementia care by streamlining multiple appointments into a single visit, enhancing efficiency and support.
背景:尽管医疗费用高昂,痴呆症患者及其护理人员仍然在护理协调和支持方面苦苦挣扎。医疗保险和医疗补助服务中心“指导改善痴呆症体验”倡议,为创新护理模式提供了机会。方法:作者试点了老年认知评估和资源参与(CARE)日,这是一个针对痴呆症患者的跨学科临床模型。在一次访问中,患者看到了老年病专家,社会工作者,职业治疗师和阿尔茨海默病协会护理专家。结果:CARE Day将四个不同的预约精简为一个,加强了协调性。老年病学家进行认知评估和护理计划。社会工作者将照顾者与支持团体和教育联系起来。职业治疗师处理日常功能、安全和认知康复需求。阿尔茨海默病协会的护理专家将家庭与记忆友好项目联系起来。随访显示患者和护理人员满意度高,协调性改善,预约失约减少。结论:跨学科临床方法通过将多个预约简化为一次就诊,提高了效率和支持,改善了痴呆症的护理。
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引用次数: 0
End-of-life care knowledge among chinese older adults: current status and influencing factors 中国老年人临终关怀知识现状及影响因素
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.1016/j.gerinurse.2026.103806
Yunfei Sun MSN , Robert Jiqi Zhang PhD , Chuqian Chen PhD
This study assessed cross-sectional end-of-life care (EoLC) knowledge among 650 adults aged 60 and above across 26 provincial-level regions in China and examined the influence of individual- and provincial-level predictors. Using repeated measures ANOVA, familiarity with 15 EoLC-related concepts was compared. Hierarchical linear regression analyzed predictors of total knowledge scores, incorporating provincial-level health and standard of living indices alongside individual factors. The average knowledge score was relatively high (42.04/60), with participants more familiar with general concepts than specific medical terms. Higher knowledge scores were associated with having an urban Hukou, working in agriculture, forestry, animal husbandry, or fishery sectors as opposed to factories before retirement, having pension insurance, better self-rated health, and caregiving experience. Provincial-level health and living standards did not significantly enhance explanatory power for cross-regional differences. The findings highlight that while participants had relatively high EoLC knowledge, individual resources and experiences were pivotal in shaping their understanding.
本研究评估了中国26个省级地区650名60岁及以上成年人的横截面临终关怀(EoLC)知识,并检验了个体和省级预测因子的影响。采用重复测量方差分析,比较了15个eolc相关概念的熟悉程度。层次线性回归分析了总知识得分的预测因子,将省级健康和生活水平指数与个人因素结合起来。平均知识得分较高(42.04/60),参与者对一般概念的熟悉程度高于对特定医学术语的熟悉程度。较高的知识得分与拥有城市户口、退休前在农业、林业、畜牧业或渔业部门(而不是工厂)工作、拥有养老保险、更好的自我评估健康和护理经验有关。省级卫生和生活水平对跨区域差异的解释力没有显著增强。研究结果强调,虽然参与者具有相对较高的EoLC知识,但个人资源和经验在形成他们的理解方面至关重要。
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引用次数: 0
Caregiver information needs in the context of dementia: A concept analysis 痴呆症背景下的照顾者信息需求:概念分析。
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.gerinurse.2026.103810
Michelle Kabakibi PhD, DNP, FNP-C, AGNP-C

Purpose

To explore the critical attributes of the concept of caregiver information needs in the context of dementia.

Background

Informal caregivers of patients with dementia need information in the postdiagnosis period; however, due to a lack of high-quality and available information, education, and support services, it is not really known what information needs are required specifically for caregivers to be successful.

Methods

The eight-step concept analysis method of Walker and Avant was used to analyze this concept. Uses of the concept, defining attributes, antecedents, consequences, and empirical referents are presented. Case samples are provided to assist in understanding the defining attributes.

Results

Caregiver information needs in the context of dementia are defined as the dynamicity of facts that apply to the disease process of dementia and that replace the lack of something requisite with adequate and useable knowledge. Identified attributes were lack of something requisite and dynamicity. Access to knowledgeable providers, motivation to be a caregiver, and the ability to coordinate care are the antecedents to caregiver information needs. Consequences included caregiver burnout, quality of life, internal locus of control, and maintaining patients in their homes.

Conclusion

Family caregivers need early, continuous, and stage-specific information that is usable to aid in their care abilities.

Implications

Education and the timing of information must be tailored to meet families' unique needs rather than a “one size fits all” approach. This, coupled with continuity of care, can empower caregivers and persons with dementia to advocate for their changing needs.
No patient or public contribution
目的:探讨痴呆背景下照顾者信息需求概念的关键属性。背景:痴呆患者非正式照护者在诊断后需要信息;然而,由于缺乏高质量和可用的信息、教育和支持服务,人们并不真正知道护理人员需要什么信息才能取得成功。方法:采用Walker和Avant的八步概念分析法对该概念进行分析。概念的使用,定义属性,先行词,结果,和经验的指称。提供案例示例以帮助理解定义属性。结果:痴呆症背景下的护理人员信息需求被定义为适用于痴呆症疾病过程的动态事实,并以足够和可用的知识取代缺乏必要的东西。识别的属性缺乏必要的东西和动态性。获得知识渊博的提供者,成为护理者的动机,以及协调护理的能力是护理者信息需求的先决条件。结果包括护理人员倦怠、生活质量、内部控制点和维持患者在家。结论:家庭照护者需要早期的、持续的、特定阶段的信息,以帮助他们提高照护能力。启示:教育和信息的时机必须量身定制,以满足家庭的独特需求,而不是“一刀切”的方法。这一点,加上护理的连续性,可以使护理人员和痴呆症患者能够倡导他们不断变化的需求。没有病人或公众捐款。
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引用次数: 0
A J-shaped relationship between Dietary Inflammatory Index and frailty risk among middle and old aged US cancer survivors 美国中老年癌症幸存者饮食炎症指数与衰弱风险之间的j型关系
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.gerinurse.2026.103885
Lin Guo MD , Qun Wang MD

Background

Frailty and dysregulated inflammation are prevalent among cancer survivors. The Dietary Inflammatory Index (DII) reflects dietary inflammation and may influence systemic inflammation, but its association with frailty remains unclear. This study investigates the relationship between DII and frailty in middle-aged and older cancer survivors.

Methods

Dietary inflammation was calculated from two 24-hour dietary recall interviews using a validated literature-derived scoring algorithm. Frailty was assessed using a 49-item frailty index integrating deficits across physical, cognitive, and clinical domains. We used weighted multivariable logistic regression and subgroup analyses to examine the DII-frailty link. Generalized Additive Models identified nonlinear associations, and a segmented linear regression model determined the inflection point.

Results

Among 2,671 U.S. participants, the adjusted odds ratio (OR) for DII and frailty was 1.09 (95% CI: 1.02, 1.17). A J-shaped relationship was observed, with an inflection point at 0.12; beyond this, the OR increased to 1.21 (95% CI: 1.09, 1.34). Subgroup analyses supported these findings.

Conclusion

DII exhibits a J-shaped association with frailty in middle-aged and older U.S. cancer survivors, highlighting the importance of dietary inflammation in frailty risk.
背景:虚弱和炎症失调在癌症幸存者中普遍存在。膳食炎症指数(DII)反映了膳食炎症,并可能影响全身炎症,但其与虚弱的关系尚不清楚。本研究调查了中老年癌症幸存者体内DII与虚弱之间的关系。方法:通过两次24小时的饮食回忆访谈,使用经过验证的文献衍生评分算法计算饮食炎症。虚弱是用49项虚弱指数来评估的,虚弱指数综合了身体、认知和临床领域的缺陷。我们使用加权多变量逻辑回归和亚组分析来检验dii -脆弱性之间的联系。广义加性模型识别非线性关联,分段线性回归模型确定拐点。结果:在2671名美国参与者中,DII和虚弱的调整优势比(OR)为1.09 (95% CI: 1.02, 1.17)。观察到j型关系,拐点在0.12;除此之外,OR增加到1.21 (95% CI: 1.09, 1.34)。亚组分析支持这些发现。结论:在美国中老年癌症幸存者中,DII与虚弱呈j型关系,强调了饮食炎症在虚弱风险中的重要性。
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引用次数: 0
Effects of overall and modality-specific exercise dose on lower-limb functional mobility in middle-aged and older adults with stroke: A systematic review and bayesian dose-response meta-analysis 总体和模式特异性运动剂量对中老年脑卒中患者下肢功能活动性的影响:一项系统综述和贝叶斯剂量-反应荟萃分析
IF 2.4 3区 医学 Q3 GERIATRICS & GERONTOLOGY Pub Date : 2026-04-01 Epub Date: 2026-01-20 DOI: 10.1016/j.gerinurse.2026.103842
Peng Bai PhD , Qiang Xiong PhD , Tao Wu PhD

Objective

This study systematically evaluated the effects of both overall and modality-specific exercise doses on lower-limb functional mobility in middle-aged and older adults with stroke, and identified optimal dose–response relationships using Bayesian non-linear modeling.

Methods

Twenty-five randomized controlled trials involving 788 stroke patients aged ≥45 years were included. Lower-limb function was assessed using the Timed Up and Go test. Exercise dose was standardized as MET·min/week, incorporating frequency, duration, and intensity. Bayesian model-based network meta-analysis was used to estimate non-linear dose-response curves across six intervention modalities: gait training, motor control training, resistance training, integrated aerobic training, combined cognitive-exercise training, and virtual reality training.

Results

A non-linear association was observed between overall exercise dose and functional mobility improvement, with a peak effect (SMD ≈ 0.45) at approximately 1400 MET·min/week. Optimal dose zones varied across modalities: resistance and gait training showed strong effects at low doses (∼560 MET·min/week), integrated aerobic and combined cognitive-exercise training peaked at higher doses (∼1700–1800 MET·min/week), while motor control training achieved significant effects (∼SMD 0.50) at moderate doses (∼890 MET·min/week). Virtual reality training exhibited wide credible intervals and non-significant effects.

Conclusion

This study demonstrates that lower-limb functional mobility in stroke patients follows a clear moderate-dose optimal pattern, with improvements peaking at around 1400 MET·min/week. Modality-specific analyses show that exercise approaches do not differ in inherent superiority but instead present distinct dose-response profiles. Evidence for virtual reality training remains inconclusive due to wide credible intervals. These findings provide quantitative guidance for dose-informed, individualized exercise prescriptions in neurorehabilitation.
目的:本研究系统评估了整体运动剂量和特定运动方式的运动剂量对中老年脑卒中患者下肢功能活动能力的影响,并利用贝叶斯非线性模型确定了最佳剂量-反应关系。方法:纳入25项随机对照试验,788例年龄≥45岁的脑卒中患者。采用Timed Up and Go测试评估下肢功能。运动剂量标准化为MET·min/周,包括频率、持续时间和强度。采用基于贝叶斯模型的网络元分析来估计六种干预方式的非线性剂量-反应曲线:步态训练、运动控制训练、阻力训练、综合有氧训练、认知-运动联合训练和虚拟现实训练。结果:总体运动剂量与功能活动能力改善之间存在非线性关联,在约1400 MET·min/week时达到峰值效应(SMD≈0.45)。最佳剂量区域因模式而异:阻力和步态训练在低剂量(~ 560 MET·min/周)表现出强烈的效果,综合有氧和联合认知运动训练在高剂量(~ 1700-1800 MET·min/周)达到峰值,而运动控制训练在中等剂量(~ 890 MET·min/周)达到显著效果(~ SMD 0.50)。虚拟现实训练具有较宽的可信区间和不显著的效果。结论:本研究表明,脑卒中患者的下肢功能活动性遵循一个明确的中剂量最佳模式,在1400 MET·min/周左右达到改善的峰值。模式特异性分析表明,运动方法在固有优势上没有差异,而是呈现出不同的剂量-反应谱。由于可信间隔较宽,虚拟现实训练的证据仍然不确定。这些发现为神经康复中剂量知情的个体化运动处方提供了定量指导。
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引用次数: 0
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Geriatric Nursing
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