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Limphocutaneous Sporotrichosis Due to Sporothrix schenckii var schenckii: A Relapsing Case after Treatment with Potassium Iodide in Elderly 老年人由申氏孢子丝菌引起的淋巴皮肤孢子菌病:碘化钾治疗后复发一例
Pub Date : 2022-01-01 DOI: 10.4236/aim.2022.124015
E. R. Juarez-Duran, S. Escandón-Pérez, Fritz Cajuste-Sequeira, L. M. Sánchez-Navarro, C. Barrera-Ochoa, R. Hernández-Castro, R. Arenas
Sporotrichosis is a subcutaneous mycosis caused by the Sporothrix schenckii complex. It has three classic clinical variants: fixed, lymphangitic, and systemic. Treatment in most cases has been itraconazole or potassium iodide. The aim of this paper is to communicate an unusual relapsing case treated with IK. We report a 73-year-old woman with lymphangitic sporotrichosis, adequate response to treatment with potassium iodide, and recurrence 15 months after. A molecular test was performed through the amplification of a 331 bp fragment of the calmodulin gene. In both infections, the same specie was isolated. The effects of potassium iodide are briefly discussed, and we conclude that the same treatment can be prescribed, if no side effects are observed.
孢子菌病是一种由申克孢子丝菌复合体引起的皮下真菌病。它有三种典型的临床变异:固定型、淋巴管型和全身性。大多数病例的治疗是伊曲康唑或碘化钾。本文的目的是沟通与IK治疗的一个不寻常的复发病例。我们报告一位73岁的淋巴管性孢子虫病妇女,对碘化钾治疗有充分的反应,15个月后复发。通过扩增331 bp的钙调蛋白基因片段进行分子测试。在这两种感染中,同一种病毒被分离出来。简要讨论了碘化钾的作用,我们得出结论,如果没有观察到副作用,可以规定同样的治疗方法。
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引用次数: 0
Optimal Growth Conditions of Microorganisms Isolated from the Buyeo Royal Tomb No. 1 and Their Effects on Painting Layers 扶余王陵1号墓微生物的最佳生长条件及其对绘画层的影响
Pub Date : 2022-01-01 DOI: 10.4236/aim.2022.129036
Hyun ju Lee, Y. Chung
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引用次数: 1
Treatment Effect of Various Concentration of Plant Extracts on Murine Norovirus 不同浓度植物提取物对小鼠诺如病毒的治疗作用
Pub Date : 2022-01-01 DOI: 10.4236/aim.2022.124018
Uchenna B. Iloghalu, Sara Miller, A. Ewunkem, J. Khatiwada, L. Williams
Noroviruses are positive-sense, single-stranded, non-enveloped RNA virus that measures approximately 27 - 35 nm in diameter. It affects humans of all ages and races causing most cases of viral gastroenteritis worldwide. Infection results from ingestion of contaminated food or water as well as causing diarrhea and vomiting in humans. Extracts from plants are known to have antioxidant, anti-inflammatory, and adhesive properties which are associated with barrier functions. The aim of this study was to elucidate whether plaque reduction was due to an effect of methanolic plant extract directly on the virus, whether the extract affects viral replication, and lastly, whether the extract disrupts the cell surface binding with the virus. The plant extracts of interest were the calyces of Hibiscus sabdariffa (HS) and the seeds of Zanthoxylum armatum (ZA). Antiviral activities of these extracts were determined against murine norovirus. The logarithmic viral reduction per pla-que-forming unit was (22 log 10 ) PFU/ml (control), (15 log 10 ) PFU/ml (treated HS), and (12 log 10 ) PFU/ml (treated ZA) with a significant reduction (68% and
诺如病毒是正义、单链、无包膜RNA病毒,直径约27 - 35nm。它影响所有年龄和种族的人类,导致世界上大多数病毒性肠胃炎病例。感染起因于摄入受污染的食物或水,以及引起人类腹泻和呕吐。众所周知,植物提取物具有抗氧化、抗炎和与屏障功能相关的粘附特性。本研究的目的是阐明斑块减少是否由于甲醇植物提取物直接作用于病毒,提取物是否影响病毒复制,最后,提取物是否破坏细胞表面与病毒的结合。研究的植物提取物为芙蓉花萼(HS)和花椒种子(ZA)。测定了这些提取物对小鼠诺如病毒的抗病毒活性。每个斑块形成单位的对数病毒减少量为(22 log 10) PFU/ml(对照组),(15 log 10) PFU/ml(治疗HS)和(12 log 10) PFU/ml(治疗ZA),显著减少(68%和68%)
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引用次数: 1
Study on the Mechanism of Intestinal Microbiota in Alzheimer’s Disease 阿尔茨海默病肠道菌群机制的研究
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.114023
土玲 车
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引用次数: 0
Research Progress of Drug Resistance in Gram-Positive Bacteria 革兰氏阳性菌耐药研究进展
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.114025
彤彤 李
The discovery of antibiotics has created a turning point for the treatment of infectious diseases, but antibiotics can also induce the development of bacterial resistance
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引用次数: 0
Screening and Characterization of Manganese(II)-Oxidizing Bacteria, and Its Application in Environmental Remediation 锰(II)氧化菌的筛选、表征及其在环境修复中的应用
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.112019
梦凡 刘
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引用次数: 0
Screening and Identification of a Halophilic Fungi and Its Optimization of Celluase Production 一株嗜盐真菌的筛选鉴定及其产纤维素酶的优化
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.112011
馨伟 李
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引用次数: 0
A Biomonitoring System of Environmental Cadmium Exposure Based on Fluorescence-Tagged Fission Yeast 基于荧光标记裂变酵母的环境镉暴露生物监测系统
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.114029
岚荣 林
Objectives: Our previous studies have constructed SPBC776.03 Δ strain of Schizosaccharomyces pombe , and shown that deficiency of SPBC776.03 gene may lead to mototic chromosome missegrega-tion during cell cycle. This work aims to establish a biomoniting system based on fission yeast to assess the genotoxity and mutangenecity of environmental cadmium ions. Methods: Rad22-GFP DNA repair foci examination, articifical mini-chromosome loss test, and real-time quantitative PCR. Results: Using PCR-based techniques and homologous recombination, a yeast strain called Rad22-GFP was constructed as an indicator of environmental genotoxic agents, in which the DNA damge associated gene Rad22 was tagged with GFP in its chromosomal locus. Under Cd exposure, this indicator strain displayed multiple (>2) DNA repair foci, whereas none was observed with untreated control. As for the positive control strain SPBC776.03 Δ, multiple (>2) DNA repair foci were observed during cell cycle even in the absence of Cd stress. Real-time qPCR analyses have revealed that, SPBC776.03 transcriptional levels were found to downregulate by three-fold when exposed to Cd 2+ , in contrast to untreated wild-type counterparts, suggesting that SPBC776.03 would be a responsive gene of fission yeast to the Cd stress. Conclusions: Our studies have constructed a biomointoring system of envirommental cadmium exposure based on fluorescence-tagged Rad22 expression, Rad22-GFP, in fission yeast, which has advantages of speediness and convenience in the assessment of Cd toxicity.
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引用次数: 0
Research Progress in the Treatment of Calcium Ions in Hypersaline Wastewater by the Mineralization of Calcium Carbonate Induced by Immobilized Halophilic Bacteria 固定化嗜盐菌诱导碳酸钙矿化处理高盐废水中钙离子的研究进展
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.112015
纪晗 王
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引用次数: 0
Advances in Studies on the Interaction between PGPR and Rhizobium PGPR与根瘤菌相互作用研究进展
Pub Date : 2022-01-01 DOI: 10.12677/amb.2022.112017
丹阳 姚
{"title":"Advances in Studies on the Interaction between PGPR and Rhizobium","authors":"丹阳 姚","doi":"10.12677/amb.2022.112017","DOIUrl":"https://doi.org/10.12677/amb.2022.112017","url":null,"abstract":"","PeriodicalId":56408,"journal":{"name":"微生物学(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66128478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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微生物学(英文)
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