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Rheological Analysis of Low Viscosity Hydrogels for 3D Bio-Printing Processes 3D生物打印低粘度水凝胶的流变学分析
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-63658
Slesha Tuladhar, Cartwright Nelson, A. Habib
Following the success of 3D printing with synthetic polymers like ABS, FLA, Nylon, etc., scientists and researchers have been putting efforts into fabricating bio-compatible materials. It has not only broadened the field of bioengineering and manufacturing but also regenerative medicine. Unlike the traditional 3D printing process, additive bio-manufacturing, also known as 3D bio-printing has a lot of challenges like cell survivability and proliferation, and the mechanical properties of the biomaterials which involve printability and the ability to hold its structural integrity. Proper design of experiments with extensive rheological investigation can help identify useful mechanical property ranges which are directly related to the geometric fidelity of 3D bio-printed scaffolds. Therefore, to investigate the printability of a low viscosity Alginate-Carboxymethyl Cellulose (CMC), multiple concentrations of the mixture were tested maintaining a 8% (w/v) solid content. A set of rheological tests such as the Steady Rate Sweep Test, Three Point Thixotropic Test (3ITT), and Amplitude test were performed. The outcome of those tests showed that the rheological properties can be controlled with the percentage of CMC in the mixtures. The fabricated filaments and scaffolds in the 5 combinations of CMC percentages were analyzed for flowability and shape fidelity. The rheological results and the printability and shape fidelity results were analyzed.
随着ABS、FLA、尼龙等合成聚合物的3D打印成功,科学家和研究人员一直在努力制造生物相容性材料。它不仅拓宽了生物工程和制造领域,也拓宽了再生医学领域。与传统的3D打印工艺不同,增材生物制造也被称为3D生物打印,它面临着许多挑战,比如细胞的生存能力和增殖能力,以及生物材料的机械性能,包括可打印性和保持其结构完整性的能力。适当设计具有广泛流变学研究的实验可以帮助确定与3D生物打印支架几何保真度直接相关的有用力学性能范围。因此,为了研究低粘度海藻酸盐-羧甲基纤维素(CMC)的可印刷性,测试了多种浓度的混合物,保持8% (w/v)的固体含量。进行了一组流变学测试,如稳定速率扫描测试、三点触变测试(3ITT)和幅度测试。试验结果表明,CMC的掺量可以控制混合料的流变性能。分析了5种CMC百分比组合下制备的纤维和支架的流动性和形状保真度。分析了材料的流变性、可打印性和形状保真度。
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引用次数: 2
Swedish Manufacturing Practices Towards a Sustainability Transition in Industry 4.0: A Resilience Perspective 瑞典制造业向工业4.0可持续转型的实践:弹性视角
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-62394
A. Chari, Johan Vogt Duberg, E. Lindahl, J. Stahre, M. Despeisse, E. Sundin, B. Johansson, M. Wiktorsson
The Swedish strategic innovation programme, Produktion2030, is a national long-term effort towards global industrial competitiveness addressing Swedish industry’s transition towards climate goals of the European Green Deal while simultaneously realising smart manufacturing and Industry 4.0 (I4.0). This paper investigated the extent of sustainability implementation and implications of I4.0 technologies through a nation-wide quantitative survey in Produktion2030’s 113 collaborative research projects. The analysis showed that 71% of the assessed projects included environmental aspects, 60% social aspects, and 45% Circular Economy (CE) aspects. Further, 65% of the projects implemented I4.0 technologies to increase overall sustainability. The survey results were compared with literature to understand how I4.0 opportunities helped derive sustainability and CE benefits. This detailed mapping of the results along with eight semi-structured interviews revealed that a majority of the projects implemented I4.0 technologies to improve resource efficiency, reduce waste in operations and incorporate CE practices in business models. The results also showed that Swedish manufacturing is progressing in the right direction of sustainability transition by deriving key resilience capabilities from I4.0-based enablers. Industries should actively adopt these capabilities to address the increasingly challenging and unpredictable sustainability issues arising in the world and for a successful transition towards sustainable manufacturing in a digital future.
瑞典战略创新计划producktion2030是一项旨在提高全球工业竞争力的国家长期努力,旨在解决瑞典工业向欧洲绿色协议的气候目标过渡的问题,同时实现智能制造和工业4.0 (I4.0)。本文通过对producktion2030的113个合作研究项目进行全国范围的定量调查,调查了工业4.0技术的可持续性实施程度和影响。分析表明,71%的评估项目包括环境方面,60%的项目包括社会方面,45%的项目包括循环经济方面。此外,65%的项目实施了工业4.0技术,以提高整体可持续性。将调查结果与文献进行比较,以了解工业4.0机会如何帮助获得可持续性和节能效益。这份详细的结果映射以及八次半结构化访谈显示,大多数项目实施了工业4.0技术,以提高资源效率,减少运营中的浪费,并将CE实践纳入商业模式。研究结果还表明,瑞典制造业正朝着可持续转型的正确方向发展,从基于4.0的推动因素中获得关键的弹性能力。工业应积极采用这些能力来解决世界上日益具有挑战性和不可预测的可持续性问题,并成功过渡到数字化未来的可持续制造。
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引用次数: 4
Prediction of Cutting Force in Bone Cutting Using Finite Element Analysis 基于有限元分析的骨切削力预测
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-63406
V. Prasannavenkadesan, P. Pandithevan
In orthopedic surgery, bone cutting is an indispensable procedure followed by the surgeons to treat the fractured and fragmented bones. Because of the unsuitable parameter values used in the cutting processes, micro crack, fragmentation, and thermal osteonecrosis of bone are observed. Therefore, prediction of suitable cutting force is essential to subtract the bone without any adverse effect. In this study, the Cowper-Symonds model for bovine bone was developed for the first time. Then the developed model was coupled with the finite element analysis to predict the cutting force. To determine the model constants, tensile tests with different strain rates (10−5/s, 10−4/s, 10−3/s, and 1/s) were conducted on the cortical bone specimens. The developed material model was implemented in the bone cutting simulation and validated with the experiments.
在骨科手术中,骨切割是外科医生治疗骨折和碎骨不可缺少的手术步骤。由于切割过程中使用的参数值不合适,观察到骨的微裂纹,碎裂和热骨坏死。因此,预测合适的切削力是必不可少的减去骨没有任何不利影响。本研究首次建立了牛骨的Cowper-Symonds模型。然后将所建立的模型与有限元分析相结合进行切削力预测。为了确定模型常数,对皮质骨试件进行了不同应变速率(10−5/s、10−4/s、10−3/s和1/s)的拉伸试验。将所建立的材料模型应用于骨切割仿真,并进行了实验验证。
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引用次数: 0
Integrating Friction-Stir Back Extrusion to Powder Metallurgy 搅拌摩擦反挤压在粉末冶金中的应用
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-64052
Sahil Dhoka, Scott W. Wagner, Himansshu Abhi, Nicholas Hendrickson, W. J. Emblom
Reducing fuel consumption has been a driving factor for researchers and manufacturers to continually develop improved methods for reducing the weight of automobiles or lightweighting. These vehicle lightweighting demands have directed researchers to look to using materials that are typically more difficult to manufacture in their studies. As a result, friction stir processing techniques are being looked at more closely. There are advantages to using friction stir methods. Dissimilar metals can be welded and fine-grained products can be created using friction stir methods to name a few. It can be an ideal solution for manufacturing high-conductive metals and alloys. Foamed aluminum tube similar to the one shown by Yoshiko Hangai et al [1] can be formed using the proposed process which could be used to develop lightweight automobile components. This paper provides preliminary results and insights gained when fine metal powders were used in a friction stir back extrusion (FSBE) setup. The tooling consisted of a D2 tool steel die with an H13 rotating probe mounted in a CNC mill. Within the die, commercially pure aluminum powder was topped by an aluminum cap with a milled pocket in the center. This pocket was used to locate the spin tool in the center of the cap and reduce the potential for the tool to drift and deflect. The cap was also used for compacting the powdered aluminum. X-ray diffraction indicated that Al13Fe4 was formed, indicating that the temperature within the die reached a minimum of 800°C and also indicated that the powder had the potential to partially sinter and melt.
减少燃料消耗一直是研究人员和制造商不断开发减少汽车重量或轻量化的改进方法的驱动因素。这些汽车轻量化的需求已经引导研究人员在他们的研究中寻找使用通常更难制造的材料。因此,摩擦搅拌处理技术正在被更密切地关注。采用摩擦搅拌法有其优点。不同的金属可以焊接,细粒度的产品可以使用摩擦搅拌方法创建,仅举几例。它是制造高导电性金属和合金的理想解决方案。类似于Yoshiko Hangai等人[1]所展示的泡沫铝管可以使用所提出的工艺形成,可用于开发轻量化汽车部件。本文提供了在摩擦搅拌反挤压(FSBE)装置中使用细金属粉末时获得的初步结果和见解。该工具由D2工具钢模具和安装在数控铣床上的H13旋转探头组成。在模具内,商业纯铝粉是由一个在中心有一个磨口袋的铝帽。这个口袋被用来定位旋转工具在中心的帽和减少潜在的工具漂移和偏转。该瓶盖还用于压实铝粉。x射线衍射表明形成了Al13Fe4,表明模具内温度至少达到800℃,也表明粉末具有部分烧结和熔化的潜力。
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引用次数: 1
Modeling and Experimental Validation of Droplet Generation in Electrohydrodynamic Inkjet Printing for Prediction of Printing Quality 电流体动力喷墨打印中液滴生成的建模与实验验证,用于打印质量预测
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-63375
Liangkui Jiang, P. Premaratne, Yanhua Huang, Zhan Zhang, H. Qin
Electrohydrodynamic (EHD) Inkjet printing is one type of micro/nano scale additive manufacturing technique. The droplet generation mechanism plays an important role in electrohydrodynamic (EHD) inkjet printing due to its significant effects on process control, printing quality, and printing performance. The large variation of printing system design used in EHD printing and the limited process optimization techniques resulted in a complex experimental procedure to determine a working condition, and it takes a long time to finish such experiments. It is also challenging to understand the droplet generation mechanism’s fluid dynamics under a multiphysical field in EHD printing. The development of computational fluid dynamics (CFD) and the recent advancements in high performance computing can be utilized to alleviate the aforementioned challenges. In this study, a numerical simulation model was developed to model the droplet generation mechanism in EHD printing based on Taylor-Melchar leaky-dielectric model. This model successfully simulated a single printing cycle, including Taylor cone formation, cone-jet generation, jet break, and jet retraction. A further simulation study demonstrated accurate predictions of the droplet volume and the jetting diameter under different working conditions (e.g., voltages and duty ratio of pulsed AC voltage). Experiments validated the simulation model and its prediction results. Such advancement in modeling can be used to optimize the printing process as well as guide the quick selection of printing conditions given a new ink.
电流体动力(EHD)喷墨打印是一种微纳米级增材制造技术。液滴的产生机理对电流体动力喷墨打印的过程控制、打印质量和打印性能有着重要的影响。由于EHD打印中使用的打印系统设计变化较大,工艺优化技术有限,导致确定工作条件的实验程序复杂,并且需要较长时间才能完成实验。在EHD打印中,多物理场条件下的液滴生成机制的流体动力学研究也是一个挑战。计算流体动力学(CFD)的发展和高性能计算的最新进展可以用来缓解上述挑战。本文基于Taylor-Melchar漏介质模型,建立了EHD打印液滴生成机理的数值模拟模型。该模型成功地模拟了单个打印周期,包括泰勒锥形成、锥射流产生、射流断裂和射流收缩。进一步的模拟研究表明,在不同的工作条件下(如脉冲交流电压的电压和占空比),可以准确预测液滴体积和喷射直径。实验验证了仿真模型及其预测结果。这种建模的进步可以用来优化印刷过程,并指导在给定新油墨的情况下快速选择印刷条件。
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引用次数: 1
Assessing the Mechanical Properties of 3D Printed Bio-Inspired Structures and Integrating Them Into a Product 评估3D打印仿生结构的机械性能并将其集成到产品中
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-60675
Binjamin Perelman, V. Sharma
The Honeycomb structure is one of the most common natural structures used in sandwich panel cores. The Enamel structure’s mechanical properties were compared to the Honeycomb structure’s mechanical properties to investigate if the Enamel structure can improve the compressive strength, stiffness and energy absorption capabilities of sandwich panel cores and potentially replace the common Honeycomb structure. Also, the optimal cellular configurations for the Honeycomb and Enamel structures were explored. Indeed, it was found the Enamel structure can potentially replace the Honeycomb structure and a wall thickness of 1.2 mm and a wall length/cell radius of 8.14 mm will maximize the natural structures mechanical properties. Furthermore, it was found that both the natural structures have good compressive strength. Therefore, the natural structures with their optimal cellular configurations were integrated into a novel automobile floor mat to ensure the mat possesses good compressive strength to resist failure or permanent deformation. Moreover, the novel automobile floor mat has a design feature that offers an efficient debris capturing and removal system that adds value to the automobile floor mat.
蜂窝结构是夹芯板芯中最常用的天然结构之一。将搪瓷结构的力学性能与蜂窝结构的力学性能进行比较,探讨搪瓷结构是否能提高夹芯板芯的抗压强度、刚度和吸能能力,并有可能取代普通蜂窝结构。同时,对蜂窝结构和搪瓷结构的最佳细胞构型进行了探讨。事实上,研究发现搪瓷结构有可能取代蜂窝结构,1.2 mm的壁厚和8.14 mm的壁长/细胞半径将最大限度地提高天然结构的力学性能。结果表明,两种天然结构均具有良好的抗压强度。因此,将具有最佳胞状结构的自然结构整合到一种新型汽车地垫中,以确保地垫具有良好的抗压强度,以抵抗破坏或永久变形。此外,新型汽车地垫的设计特点是提供了一个有效的碎片捕获和清除系统,为汽车地垫增加了价值。
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引用次数: 0
Deformation Analysis of 3D Printed Metacarpophalangeal and Interphalangeal Joints via Transfer Learning 基于迁移学习的3D打印掌指关节和指间关节变形分析
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-63623
Juan Diego Toscano, Sahand Hajifar, Christian Oswaldo Segura, Luis Javier Segura, Hongyue Sun
A cast/brace is a tight garment that restricts the movement and provides support to an injured zone. Traditional casts/braces suffer from material wastage, discomfort, patient dissatisfaction, odor, unnecessary weight, and dangerous extraction procedures. These issues can be solved partially by constructing the casts/braces via 3D printing. Toward this end, we print the personalized metacarpal casts/braces (MCB) via fused deposition modeling (FDM), and investigate their mechanical properties to ensure the desired functionality. However, printing the full-size MCB is time-consuming (takes more than 11 hours in our design), making it hard to collect a sufficient data set for the mechanical properties investigation. Here, we explore the utilization of reduced-size MCB to facilitate the analysis of full-size MCB via transfer learning. In particular, three critical process variables (i.e., raster width, layer height, and extrusion temperature) were varied, and a universal testing machine was used to measure the total deformation of the MCB. We then perform the prediction of the deformation in full-size MCB with transfer learning of data from reduced-size MCB and limited data from full-size MCB. From the case study, the transfer learning approach can reduce the needs of data collection in the time-consuming full-size MCB by leveraging the information from reduced-size MCB.
石膏/支架是一种紧绷的衣服,限制运动并为受伤区域提供支持。传统的铸型/牙套存在材料浪费、不适、患者不满、气味、不必要的重量和危险的拔牙过程。这些问题可以通过3D打印来部分解决。为此,我们通过熔融沉积建模(FDM)打印个性化掌骨铸件/支架(MCB),并研究其机械性能以确保所需的功能。然而,打印全尺寸MCB非常耗时(在我们的设计中需要超过11个小时),因此很难收集足够的数据集来进行机械性能调查。在此,我们探讨了通过迁移学习,利用缩小尺寸的MCB来促进对完整尺寸MCB的分析。特别地,改变三个关键工艺变量(即光栅宽度、层高和挤出温度),并使用通用试验机测量MCB的总变形。然后,我们使用来自缩小尺寸MCB的数据和来自全尺寸MCB的有限数据的迁移学习来预测全尺寸MCB的变形。从案例研究中可以看出,迁移学习方法可以利用小尺寸MCB的信息,减少耗时的全尺寸MCB的数据收集需求。
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引用次数: 2
Magnetic Field Assisted 3D Printing of Limpet Teeth Inspired Polymer Matrix Composite With Compression Reinforcement 磁场辅助3D打印帽贝齿启发聚合物基复合材料与压缩增强
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-61050
Dylan Joralmon, Evangeline A. Amonoo, Yizhen Zhu, Xiangjia Li
Lightweight and cost-effective polymer matrix composites (PMCs) with extraordinary mechanical performance will be a key to the next generation of diverse industrial applications such as aerospace, electric automobile, and biomedical devices. Limpet teeth made of mineral-polymer composites have been proved as nature’s strongest material due to the unique hierarchical architectures of mineral fiber alignment. Here, we present an approach to build limpet teeth inspired structural materials with precise control of geometric morphologies of microstructures by magnetic field-assisted 3D printing (MF-3DP). α-Iron (III) oxide-hydroxide nanoparticles (α-FeOOHs) are aligned by the magnetic field during 3D printing and aligned α-FeOOHs bundles are further grown to aligned goethite-based bundles (aGBs) by rapid thermal treatment after printing. The mechanical reinforcement of goethite-based fillers in PMCs can be modulated by adjusting the geometric morphology and alignment of mineral particles encapsulated inside the 3D printed PMCs. In order to identify the mechanical enhancement mechanism, physics-based modeling, simulation, and tests were conducted and the results further guided the design of bioinspired goethite-based PMCs. The correlation of the geometric morphology of self-assembled α-FeOOHs, curing characteristics of α-FeOOHs/polymer composite, and process parameters were identified to establish the optimal design of goethite-based PMCs. The 3D-printed PMCs with aGBs show promising mechanical reinforcement. This study opens intriguing perspectives for designing high strength 3D printed PMCs on the basis of bioinspired architectures with customized configurations.
具有优异机械性能的轻质、高性价比聚合物基复合材料(pmc)将成为下一代航空航天、电动汽车和生物医学设备等多种工业应用的关键。由矿物-聚合物复合材料制成的帽贝牙齿被证明是自然界最坚固的材料,因为矿物纤维排列的独特层次结构。在这里,我们提出了一种通过磁场辅助3D打印(MF-3DP)精确控制微结构几何形态来构建帽贝齿启发结构材料的方法。在3D打印过程中,α-氧化铁(III) -氢氧化物纳米粒子(α-FeOOHs)在磁场作用下排列,排列好的α-FeOOHs束在打印后通过快速热处理进一步生长为排列的针铁矿基束(aGBs)。通过调整包裹在3D打印pmc内部的矿物颗粒的几何形态和排列,可以调节pmc中针铁矿基填料的机械增强。为了明确针铁矿的力学增强机制,开展了基于物理的建模、仿真和试验,并进一步指导了仿生针铁矿pmc的设计。研究了自组装α-FeOOHs的几何形态、α-FeOOHs/聚合物复合材料的固化特性与工艺参数的相关性,建立了针铁矿基pmc的优化设计。具有agb的3d打印pmc显示出有希望的机械增强。这项研究为设计具有定制配置的生物启发架构的高强度3D打印pmc开辟了有趣的视角。
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引用次数: 6
Selective Laser Melting of Stainless Steel 316L for Mechanical Property-Gradation 316L不锈钢机械性能分级的选择性激光熔化
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-64108
Yash Parikh, Mathew Kuttolamadom
With an end goal of creating single-alloy functionally-graded additively manufactured (FGAM) parts, this paper investigates the manufacture and properties of stainless steel 316L samples via a pulsed selective laser melting (SLM) process. The focus is on elucidating the underlying causes of property variations (within a functionally-acceptable range) through material characterization and testing. Five samples (made via different volumetric energy density-based process parameter sets) were down-selected from preliminary experimental results and analyzed for their microstructure, mechanical and physical properties (hardness, density/porosity, Young’s modulus). It was observed that property variations resulted from combinations of porosity types/amounts, martensitic phase fractions, and grain sizes. Based on these, various functionally-graded specimens of different sizes were built as per ASTM standards, each having intended property changes along its gauge volumes. The presented findings establish that a methodical control of microstructure and mechanical properties could be obtained in a repeatable and reproducible manner by changing the process parameters. This work lays the foundation for understanding and tuning the global mechanical performance of FGAM bulk structures as well as the role of interfacial zones.
以制造单合金功能梯度增材制造(FGAM)零件为最终目标,本文通过脉冲选择性激光熔化(SLM)工艺研究了不锈钢316L样品的制造和性能。重点是通过材料表征和测试阐明性能变化(在功能可接受范围内)的潜在原因。从初步实验结果中选择了5个样品(通过不同的基于体积能量密度的工艺参数集制作),并分析了它们的微观结构、力学和物理性能(硬度、密度/孔隙率、杨氏模量)。观察到孔隙类型/数量、马氏体相分数和晶粒尺寸的组合导致了材料性能的变化。在此基础上,根据ASTM标准构建了不同尺寸的各种功能分级试样,每个试样都具有沿其测量体积的预期性能变化。所提出的研究结果表明,通过改变工艺参数,可以以可重复和可再现的方式获得微观结构和力学性能的系统控制。这项工作为理解和调整FGAM体结构的整体力学性能以及界面区的作用奠定了基础。
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引用次数: 0
Experimental Investigation Into the Fabrication of Porous Biodegradable Fe Scaffold by Microwave Sintering of 3D Printed Green Body 微波烧结3D打印绿色体制备多孔可生物降解铁支架的实验研究
Pub Date : 2021-08-04 DOI: 10.1115/msec2021-63402
D. Mishra, P. M. Pandey
Iron has appealing biodegradable properties that makes compatible for biodegradable implant tools applications. Although, the slow corrosion rate of Fe made obsolete for biomedical applications. The incorporation of the porous structure may result in an enhanced degradation rate. The main advantage offer by the porous structure is to allow to flow the body transportation fluid through it and ease to proliferate the new tissue. Therefore, the current work focused on the development of a porous Fe structures using micro-extrusion based three-dimensional printing (ME3DP) and pressure less microwave sintering. The metallic-based polymeric ink used to fabricate the intent design structure. Subsequently, samples were heated in the microwave sintering furnace. The experimentations were done to evaluate the outcomes of different Fe concentrations (91–95 wt.%) on density and compressive yield strength of developed porous parts. Experimental observation deduced that fabricated part ≥ 94.wt.% of Fe concentration has strong bonding strength between the printed layers. Moreover, the mechanical property of 94 wt.% has found greater than 95 wt.% of Fe concentration. The scanning electron microscopic (SEM) image illustrated the presence of porous morphology into the fabricated body. Additionally, XRD (X-ray diffraction) plots exhibited the purity of sample without any contamination residue.
铁具有吸引人的可生物降解特性,使其与可生物降解植入工具的应用相兼容。尽管如此,铁的缓慢腐蚀速度使其在生物医学应用中过时了。多孔结构的掺入可以提高降解率。多孔结构提供的主要优点是允许身体运输液体通过它,并且易于新组织增殖。因此,目前的工作重点是利用基于微挤压的三维打印(ME3DP)和无压微波烧结技术开发多孔铁结构。用于制造意图设计结构的金属基聚合油墨。随后,样品在微波烧结炉中加热。研究了不同铁浓度(91 ~ 95 wt.%)对多孔件密度和抗压屈服强度的影响。实验观察推断,制件≥94.wt。%的铁浓度具有较强的印刷层之间的结合强度。此外,在94 wt.%的力学性能中发现了大于95 wt.%的铁浓度。扫描电镜(SEM)图像表明,在制备体中存在多孔形态。此外,XRD (x射线衍射)图显示样品纯度高,没有任何污染残留。
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引用次数: 1
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