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The application of digital holography for accurate three-dimensional localisation of mosquito-bednet interaction 数字全息技术在蚊蚊帐相互作用的精确三维定位中的应用
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.020
Matthew L. Hall, K. Gleave, Angela Hughes, P. McCall, C. Towers, D. Towers
Understanding mosquito interaction with long-lasting insecticidal bednets is crucial in the development of more effective intervention methods to protect humans from malaria transmission. As such, a 240 × 240 × 1000 mm laboratory setup for the in-line recording of digital holograms and subsequent in-focus reconstruction and 3D localisation of mosquitoes is presented. Simple bednet background removal methods are used to accurately localise a mosquito obscured by a bednet in 3D coordinates. Simulations and physical data demonstrate that this method is suitable for mosquitoes positioned 3-1000 mm behind a bednet. A novel post-processing technique, involving a cascade-correlation of a Tamura of Intensity focus metric extracted from digitally reconstructed scenes, accurately localises mosquitoes positioned 35-100 mm behind a bednet from a single digital hologram. The result of this study is a scalable digital holographic methodology to examine mosquito-bednet interaction in 3D at a level of accuracy previously only seen in 2D imaging of mosquitoes in a much smaller volume.
了解蚊子与长效杀虫蚊帐的相互作用对于开发更有效的干预方法以保护人类免受疟疾传播至关重要。因此,提出了一个240 × 240 × 1000毫米的实验室装置,用于在线记录数字全息图和随后的聚焦重建和蚊子的3D定位。简单的蚊帐背景移除方法用于在三维坐标中精确定位被蚊帐遮挡的蚊子。模拟和物理数据表明,该方法适用于位于蚊帐后3-1000毫米的蚊子。一种新的后处理技术,涉及从数字重建场景中提取的田村强度焦点度量的级联相关,从单个数字全息图中准确定位位于蚊帐后35-100毫米的蚊子。这项研究的结果是一种可扩展的数字全息方法,可以在3D中检测蚊子与蚊帐的相互作用,其精确度以前只在蚊子的2D成像中看到,而蚊子的体积要小得多。
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引用次数: 2
Design of broadband terahertz vector and vortex beams: I. Review of materials and components 宽带太赫兹矢量和涡旋光束的设计:1 .材料和元件综述
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.043
N. Petrov, B. Sokolenko, M. Kulya, Andrei Gorodetsky, A. Chernykh
Design of broadband terahertz vector and vortex beams: I. Review of materials and Components. Light: Abstract In this paper, we review the existing approaches for vortex and vector beam shaping and generation in the terahertz frequency range. The particular focus of this review is on the possibility of homogeneous topological charge formation in the ultra-wide spectral interval inherent to ultrashort terahertz pulses. We review the available materials and components, analyse proposed and potentially possible solutions for broadband terahertz vortex and vector beam shaping, compare all developed approaches, and put forward a unified concept for constructing passive shapers of such beams from the existing component base.
宽带太赫兹矢量和涡旋光束的设计:1 .材料与元件综述。摘要本文综述了现有的太赫兹涡旋和矢量光束的形成和产生方法。本综述特别关注的是在超短太赫兹脉冲固有的超宽光谱区间内形成均匀拓扑电荷的可能性。我们回顾了可用的材料和组件,分析了宽带太赫兹涡旋和矢量光束整形的建议和潜在可能的解决方案,比较了所有开发的方法,并提出了一个统一的概念,从现有的组件基础上构建这种光束的被动整形器。
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引用次数: 15
A quasi-3D fano resonance cavity on optical fiber end-facet for high signal-to-noise ratio dip-and-read surface plasmon sensing 用于高信噪比浸读表面等离子体传感的光纤端面准三维法诺谐振腔
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.046
Xiaqing Sun, Zeyu Lei, Hao Zhong, Chenjia He, Sihang Liu, Qingfeng Meng, Qingwei Liu, Shengfu Chen, Xiangyang Kong, Tian Yang
Surface plasmon devices mounted at the end-facets of optical fibers are appealing candidates for rapid and pointof-care sensing applications, by offering a special dip-and-read operation mode. At present, these devices’ noiseequivalent limits-of-detection lag far behind the free-space counterparts, leaving them incapable of most biosensing applications. Here we report a quasi-3D Fano resonance cavity and its fabrication method to fundamentally improve the quality factor and coupling efficiency for fiber-coupled surface plasmon resonance. In this device, the Fano resonance combines the high coupling efficiency of a Fabry-Pérot etalon and the high quality factor resonance of a plasmonic crystal cavity. The quasi-3D device was fabricated on a planar substrate and transferred to a single-mode fiber end-facet, which requires a low-adhesion yet surface-plasmon-tunneling interface between the device and the planar substrate. Such an interface was realized with a nanocap-slit unit structure, of which the plasmonic crystal was consisted. A noise-equivalent limit of detection of ~ 10 RIU was experimentally obtained, allowing bovine serum albumin physical adsorption to be distinguished at ng mL level concentrations. Therefore, breaking through the long-standing signal-to-noise ratio bottleneck, this work makes fiber end-facet surface plasmon devices into one of high sensitivity label-free sensing technologies. At the same time, it provides an enabling top-down fabrication technology for making 3D plasmonic structures on fiber endfacets at the nanometer scale.
安装在光纤端面的表面等离子体器件通过提供特殊的浸入和读取操作模式,成为快速和点对点传感应用的有吸引力的候选者。目前,这些设备的噪声当量检测限制远远落后于自由空间设备,使它们无法用于大多数生物传感应用。本文报道了一种准三维法诺谐振腔及其制备方法,从根本上提高了光纤耦合表面等离子体共振的质量因子和耦合效率。在该装置中,法诺共振结合了法布里-帕姆罗标准子的高耦合效率和等离子体晶体腔的高质量因数共振。准三维器件被制作在平面衬底上并转移到单模光纤端面,这要求器件与平面衬底之间具有低粘附但表面等离子体隧穿的界面。这种界面是用纳米帽-狭缝单元结构实现的,等离子体晶体由该单元结构组成。实验获得了~ 10 RIU的噪声等效检测限,使牛血清白蛋白在ng mL浓度下的物理吸附得以区分。因此,本工作突破了长期存在的信噪比瓶颈,使光纤端面表面等离子体器件成为高灵敏度无标签传感技术之一。同时,为在纳米尺度上在光纤端面上制作三维等离子体结构提供了一种自顶向下的制造技术。
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引用次数: 6
Digital holography as metrology tool at micro-nanoscale for soft matter 数字全息术作为软物质微纳米尺度的测量工具
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.010
Zhe Wang, L. Miccio, S. Coppola, V. Bianco, P. Memmolo, V. Tkachenko, V. Ferraro, E. Maio, P. Maffettone, P. Ferraro
The appearance of the first laser approximately 12 years after the invention of holography by Gabor (1948) revolutionized the field of optical metrology. In fact, the invention of holographic interferometry enabled the exploitation of interferometry on non-mirror surfaces and full-scale objects. The holography-based measurement methods has been implemented to several industrial systems or in support of R&D with the aim of improving new products in many fields (automotive, aerospace, electronics, etc.). To date, holography has been considered an important measurement tool for non-destructive inspection (NDI), strain-stress measurement, and vibration analysis at various engineering sites. Recently, the new paradigm of Industry4.0 has seen the introduction of new technologies and methods of processing materials as well as the development of manufacturing approaches for the realization of innovative products. For example, direct printing, additive, and bottom-up manufacturing processes are expected to involve new ways of making products in future, and most innovative fabrication processes will be based on the manipulation of soft matter (e.g., starting from the liquid phase) that will be shaped at the nanoscale. The inherent characteristics of digital holography (DH) make it a powerful and accurate tool for the visualization and testing of final products, as well as for in situ and real-time monitoring and quantitative characterization of the processes involved during the fabrication cycle. This review aims to report on the most useful applications of soft matter, where the capabilities offered by DH, such as three-dimensional (3D) imaging, extended focus, 3D tracking, full-field analysis, high sensitivity, and a wide range of measurements from nanometers to centimeters, permit completely non-invasive characterizations on a full-scale. Several holographic experimental results of typical samples are reported and discussed where DH plays a primary role as a tool gauge for soft matter. ACCEPTED ARTICLE PREVIEW
在Gabor(1948)发明全息术大约12年后,第一台激光器的出现彻底改变了光学计量学领域。事实上,全息干涉术的发明使干涉术在非镜面和全尺寸物体上的应用成为可能。基于全息术的测量方法已经实施到几个工业系统或支持研发,目的是改进许多领域(汽车,航空航天,电子等)的新产品。迄今为止,全息技术已被认为是无损检测(NDI)、应变-应力测量和各种工程现场振动分析的重要测量工具。最近,工业4.0的新范式已经引入了新的材料加工技术和方法,以及实现创新产品的制造方法的发展。例如,直接印刷、添加剂和自下而上的制造工艺预计将涉及未来制造产品的新方法,大多数创新的制造工艺将基于对软物质的操纵(例如,从液相开始),这些软物质将在纳米尺度上成形。数字全息术(DH)的固有特性使其成为最终产品可视化和测试的强大而准确的工具,以及在制造周期中所涉及的过程的现场和实时监控和定量表征。本综述旨在报告软物质最有用的应用,其中DH提供的功能,如三维(3D)成像,扩展聚焦,3D跟踪,全视野分析,高灵敏度,从纳米到厘米的广泛测量范围,允许在全尺寸上进行完全无创的表征。本文报道并讨论了几个典型样品的全息实验结果,其中DH作为软物质的测量工具发挥了主要作用。接受文章预览
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引用次数: 17
A symmetry concept and significance of fringe patterns as a direct diagnostic tool in artwork conservation 条纹图案的对称概念及其在艺术品保护中的直接诊断意义
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.018
V. Tornari
Coherent metrology has gained great importance as a branch of highly accurate, non-destructive, precise measurement technology for industrial, aeronautic, medical, and other applications. However, the fringe patterns produced seem to be enigmatic in terms of comprehension and analysis. Many laboratories are involved in improving hardware and software to keep unlocking the unique diagnostic capacities offered through the development of coherent metrology techniques. However, these advancements are not equally well suited for solving problems in all fields of application. The structural diagnosis of artwork is a distinctive field to which coherent metrology is applied. Works of art are unique constructions for which there are strict handling and moral rules aimed at their preservation. Fringe pattern evaluation provides much information about the condition of artwork being investigated, and establishing fringe patterns is one of the most efficient structural deformation and defect detection diagnostic tools. Previous collaborative studies have shown the main fringe patterns and their typical classification with regard to defects. Nevertheless, the complexity of the results prevents defect detection automation based on a fringe pattern classification table. The use of fringe patterns for the structural diagnosis of artwork is important for conveying crucial detailed information and dense data sources that are unmatched compared to those obtained using other conventional or modern techniques. Hologram interferometry fringe patterns uniquely reveal existing and potential structural conditions independent of object shape, surface complexity, material inhomogeneity, and multilayered and mixed media structures, without requiring contact and interaction with the precious surface. Thus, introducing a concept that allows fringe patterns to be considered as a powerful standalone physical tool for direct structural condition evaluation with a focus on artwork conservators’ need for structural diagnosis is crucial. The gravity of this aim intensifies when the particularities of ethics and safety in the field of art conservation are considered. There are ways to obtain the advantages of fringe patterns even when specialized software and advanced analysis algorithms fail to convey usable information. Interactively treating the features of fringe patterns through step-wise reasoning formulates the knowledge basis to automate defect isolation and identification procedures for machine learning and artificial intelligence (AI) development. The transfer of understanding of the significance of these fringe patterns to an AI system through logical steps is this work’s ultimate technical aim. Research on this topic is ongoing.
相干计量作为高精度、非破坏性、精密测量技术的一个分支,在工业、航空、医疗和其他应用中具有重要意义。然而,产生的条纹图案在理解和分析方面似乎是神秘的。许多实验室都参与了硬件和软件的改进,以通过开发一致的计量技术来不断释放独特的诊断能力。然而,这些进步并不同样适用于解决所有应用领域的问题。艺术品的结构诊断是相干计量学应用的一个独特领域。艺术作品是独特的建筑,有严格的处理和道德规则,旨在保护它们。条纹模式的评估提供了许多关于被调查艺术品状况的信息,并且建立条纹模式是最有效的结构变形和缺陷检测诊断工具之一。以往的合作研究已经显示了主要的条纹模式及其典型的缺陷分类。然而,结果的复杂性阻碍了基于条纹模式分类表的缺陷检测自动化。使用条纹模式对艺术品进行结构诊断对于传达关键的详细信息和密集的数据源是非常重要的,这与使用其他传统或现代技术获得的数据相比是无与伦比的。全息干涉条纹图独特地揭示了现有的和潜在的结构条件,不依赖于物体形状、表面复杂性、材料不均匀性、多层和混合介质结构,而不需要与珍贵的表面接触和相互作用。因此,引入一个概念,允许条纹图案被认为是一个强大的独立的物理工具,用于直接的结构状况评估,重点是艺术品保护人员对结构诊断的需求,这是至关重要的。当考虑到艺术保护领域的伦理和安全的特殊性时,这一目标的严重性就会加剧。即使专门的软件和先进的分析算法不能传达有用的信息,也有办法获得条纹图案的优点。通过逐步推理交互式地处理条纹图案的特征,为机器学习和人工智能(AI)开发提供了自动化缺陷隔离和识别过程的知识基础。通过逻辑步骤将对这些边缘模式重要性的理解转移到人工智能系统中是这项工作的最终技术目标。关于这一主题的研究正在进行中。
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引用次数: 6
Crystal plane engineering of MAPbI3 in epoxy-based materials for superior gamma-ray shielding performance MAPbI3在环氧基材料中的晶体平面工程,具有优异的伽马射线屏蔽性能
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.051
Kai Cui, Yang Li, W. Wei, Qianqian Teng, Tianyu Zhang, Jinzhu Wu, Hongjun Kang, W. Qin, Xiaohong Wu
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引用次数: 1
Ultra-high speed holographic shape and displacement measurements in the hearing sciences 听觉科学中的超高速全息形状和位移测量
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.015
Haimi Tang, P. Psota, J. Rosowski, C. Furlong, J. Cheng
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引用次数: 4
Celebrating Holography after 60 years of successful application 庆祝全息技术成功应用60周年
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.038
W. Osten, R. Kowarschik, Yuhong Bai
The invention of Holography by Dennis Gabor goes back to the year 1948. Gabor could show that the complete original wavefront of the object both with its amplitude and phase can be reconstructed by adding a coherent background to a wave coming from an object while recording in a storage medium. However, because no adequate source of coherent light was available at this time, the small coherence length of the mercury lamp forced him to arrange everything along one axis. This setup, known as in-line holography, has the disadvantage that the desired reconstruction is in line with disturbing diffraction orders, and can be separated from these disturbances only by focusing. Gabor finally gave up his investigations and mentioned in 1955 to his collaborator Michael W. Haine, “ It was a very ill wind which I let out now almost eight years ago which blew nobody any good, least of all to myself.” The holographic principle, on which Gabor had set his high hopes, especially with respect to the enhancement of the resolution of the electronic microscope, seemed to retain only the status of a scientific curiosity. But the breakthrough would be achieved a couple of years later. In the early 1960s, Emmett Leith and Juris Upatnieks, two physicists at the University of Michigan, implemented their off-axis scheme as a smart combination of Gabor’s holographic principle with the carrier frequency technique known from side-looking radar. Their famous publication came out 61 years ago in 1961. In this way the twin image problem could be effectively eliminated. However, it resulted in the requirement of increased temporal coherence which could be satisfied using a powerful coherent light source only. Such a source was soon available. In 1958, Charles Townes at the Columbia University, and a Russian research group led by Nicolay Basov and Aleksandr Prokhorov at the Lebedev Institute for Physics, Moscow, simultaneously and independently analyzed the possibilities of applying the principle of the Microwave Amplification by Stimulated Emission of Radiation (MASER) for the optical region of the electromagnetic spectrum. The first operating optical MASER, now known as the laser, was constructed by Maiman and was demonstrated at the Hughes Research Laboratories in Malibu, California, in 1960. The symbiosis of the holographic and laser principle opened the door for a large variety of new technologies and applications in optical imaging, information processing, and metrology. The 1960s were filled with a variety of successful practical applications and innovations such as display or volume holography, computer generated holography, holographic interferometry, holographic nondestructive testing, holographic pattern recognition, and holographic storage technology. Gabor took an active part in this development. 50 years ago, on the occasion of his Nobel lecture at the Imperial Colleges in 1971, he also tried to take a look into the future of holography. Gabor mentioned “However, the
Dennis Gabor发明的全息术可以追溯到1948年。Gabor可以证明,在存储介质中记录时,通过向来自物体的波添加相干背景,可以重建物体的完整原始波前,包括其振幅和相位。然而,由于当时没有足够的相干光源,水银灯的小相干长度迫使他把所有东西都安排在一个轴上。这种设置,被称为在线全息,有缺点,所需的重建是符合干扰的衍射顺序,并且可以从这些干扰中分离只有通过聚焦。Gabor最终放弃了他的调查,并在1955年向他的合作者Michael W. Haine提到,“这是我大约八年前释放的一股非常不好的风,对任何人都没有好处,尤其是对我自己。”加博尔曾寄予厚望的全息原理,特别是关于提高电子显微镜分辨率的全息原理,似乎只保留了一种科学珍品的地位。但这一突破将在几年后实现。在20世纪60年代早期,密歇根大学的两位物理学家Emmett Leith和Juris Upatnieks实现了他们的离轴方案,将Gabor的全息原理与侧视雷达的载频技术巧妙地结合起来。他们著名的出版物出版于61年前的1961年。这样可以有效地消除双象问题。然而,这导致了对时间相干性的要求增加,只有使用强大的相干光源才能满足这一要求。这样的消息来源很快就得到了。1958年,哥伦比亚大学的查尔斯·汤斯(Charles Townes)和莫斯科列别捷夫物理研究所的尼古拉·巴索夫(Nicolay Basov)和亚历山大·普罗霍罗夫(Aleksandr Prokhorov)领导的俄罗斯研究小组同时独立地分析了将微波受激辐射放大(MASER)原理应用于电磁波谱光学区域的可能性。第一台可操作的光学微波激射器,现在被称为激光器,是由梅曼建造的,并于1960年在加利福尼亚州马里布的休斯研究实验室进行了演示。全息和激光原理的共生为光学成像、信息处理和计量学中的各种新技术和应用打开了大门。20世纪60年代充满了各种成功的实际应用和创新,如显示或体全息、计算机生成全息、全息干涉测量、全息无损检测、全息模式识别和全息存储技术。Gabor积极参与了这一发展。50年前,1971年他在帝国理工学院发表诺贝尔奖演讲时,他也试图展望全息术的未来。Gabor说:“然而,在一些重要的领域我们可以做得更多,在这些领域我们急需改进。这是用于存储和显示微全息图的区域。一个更雄心勃勃的计划,可能在更远的未来,是三维电影摄影,不需要像宝丽来这样的观看辅助工具。”基本的
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引用次数: 2
Phase microscopy and surface profilometry by digital holography 数字全息相显微镜和表面轮廓术
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.019
Myung K. Kim
Quantitative phase microscopy by digital holography is a good candidate for high-speed, high precision profilometry. Multi-wavelength optical phase unwrapping avoids difficulties of numerical unwrapping methods, and can generate surface topographic images with large axial range and high axial resolution. But the large axial range is accompanied by proportionately large noise. An iterative process utilizing holograms acquired with a series of wavelengths is shown to be effective in reducing the noise to a few micrometers even over the axial range of several millimeters. An alternate approach with shifting of illumination angle, instead of using multiple laser sources, provides multiple effective wavelengths from a single laser, greatly simplifying the system complexity and providing great flexibility in the wavelength selection. Experiments are performed demonstrating the basic processes of multi-wavelength digital holography (MWDH) and multi-angle digital holography (MADH). Example images are presented for surface profiles of various types of surface structures. The methods have potential for versatile, high performance surface profilometry, with compact optical system and straightforward processing algorithms.
数字全息定量相显微术是高速、高精度轮廓测量的理想选择。多波长光学相位展开避免了数值展开方法的困难,可以生成轴向范围大、轴向分辨率高的地表地形图像。但轴向范围大,噪声也相应大。利用一系列波长全息图的迭代过程被证明可以有效地将噪声降低到几微米,甚至在几毫米的轴向范围内。另一种替代方法是改变照明角度,而不是使用多个激光源,从单个激光中提供多个有效波长,大大简化了系统的复杂性,并在波长选择方面提供了很大的灵活性。实验证明了多波长数字全息(MWDH)和多角度数字全息(MADH)的基本过程。给出了各种类型表面结构的表面轮廓的示例图像。该方法具有多功能、高性能表面轮廓测量的潜力,具有紧凑的光学系统和简单的处理算法。
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引用次数: 5
Towards in-situ diagnostics of multi-photon 3D laser printing using optical coherence tomography 光学相干层析成像用于多光子三维激光打印的原位诊断
Pub Date : 2022-01-01 DOI: 10.37188/lam.2022.039
R. Zvagelsky, Frederik Mayer, D. Beutel, C. Rockstuhl, G. Gomard, M. Wegener
In recent years, multi-photon 3D laser printing has become a widely used tool for the fabrication of micro- and nanostructures for a large variety of applications. Typically, thorough sample characterisation is key for an efficient optimisation of the printing process. To date, three-dimensional microscopic inspection has usually been carried out on finished 3D printed microstructures, that is, using ex-situ approaches. In contrast, in-situ 3D characterization tools are desirable for quickly assessing the quality and properties of 3D printed microstructures. Along these lines, we present and characterise a Fourier-domain optical coherence tomography (FD-OCT) system that can be readily integrated into an existing 3D laser lithography setup. We demonstrate its capabilities by examining different 3D printed polymer microstructures immersed in a liquid photoresist. In such samples, local reflectivity arises from the (refractive-index) contrasts between the polymerised and non-polymerised regions. Thus, the refractive index of the printed material can be extracted. Furthermore, we demonstrate that the reflectivity of polymer-monomer transitions exhibits time-dependent behaviour after printing. Supported by transfer-matrix calculations, we explain this effect in terms of the time-dependent graded-index transition originating from monomer diffusion into the polymer matrix. Finally, we show exemplary 3D reconstructions of printed structures that can be readily compared with 3D computer designs.
近年来,多光子3D激光打印已成为一种广泛应用于微纳米结构制造的工具。通常,彻底的样品表征是有效优化印刷过程的关键。迄今为止,三维显微检查通常是在成品3D打印微观结构上进行的,即使用非原位方法。相比之下,原位3D表征工具对于快速评估3D打印微结构的质量和性能是可取的。沿着这些思路,我们提出并描述了一个傅立叶域光学相干层析成像(FD-OCT)系统,该系统可以很容易地集成到现有的3D激光光刻装置中。我们通过检查浸泡在液体光刻胶中的不同3D打印聚合物微结构来展示其功能。在这些样品中,局部反射率来自聚合区和非聚合区之间的(折射率)对比。因此,可以提取打印材料的折射率。此外,我们证明了聚合物-单体过渡的反射率在印刷后表现出时间依赖的行为。在转移矩阵计算的支持下,我们用源于单体扩散到聚合物基体的随时间变化的梯度指数转变来解释这种效应。最后,我们展示了打印结构的典型3D重建,可以很容易地与3D计算机设计进行比较。
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引用次数: 7
期刊
光:先进制造(英文)
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